CN108780056B - 用于样品表征的介电感测 - Google Patents

用于样品表征的介电感测 Download PDF

Info

Publication number
CN108780056B
CN108780056B CN201780009585.5A CN201780009585A CN108780056B CN 108780056 B CN108780056 B CN 108780056B CN 201780009585 A CN201780009585 A CN 201780009585A CN 108780056 B CN108780056 B CN 108780056B
Authority
CN
China
Prior art keywords
permittivity
dielectric constant
radio frequency
dielectric
input
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201780009585.5A
Other languages
English (en)
Chinese (zh)
Other versions
CN108780056A (zh
Inventor
M·苏斯特
P·莫希尼
D·马吉
E·斯塔夫罗
U·古尔干
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Case Western Reserve University
Original Assignee
Case Western Reserve University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Case Western Reserve University filed Critical Case Western Reserve University
Publication of CN108780056A publication Critical patent/CN108780056A/zh
Application granted granted Critical
Publication of CN108780056B publication Critical patent/CN108780056B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/026—Dielectric impedance spectroscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/04—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
    • G01N27/06—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
    • G01N27/08—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid which is flowing continuously
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/22—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance
    • G01N27/221—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance by investigating the dielectric properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Ecology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Optics & Photonics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
CN201780009585.5A 2016-01-15 2017-01-17 用于样品表征的介电感测 Active CN108780056B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662279467P 2016-01-15 2016-01-15
US62/279,467 2016-01-15
PCT/US2017/013797 WO2017124104A1 (en) 2016-01-15 2017-01-17 Dielectric sensing for sample characterization

Publications (2)

Publication Number Publication Date
CN108780056A CN108780056A (zh) 2018-11-09
CN108780056B true CN108780056B (zh) 2022-03-25

Family

ID=59311590

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780009585.5A Active CN108780056B (zh) 2016-01-15 2017-01-17 用于样品表征的介电感测

Country Status (9)

Country Link
US (2) US10674931B2 (https=)
EP (1) EP3403080B1 (https=)
JP (1) JP6936235B2 (https=)
KR (1) KR102810749B1 (https=)
CN (1) CN108780056B (https=)
AU (1) AU2017207027B2 (https=)
BR (1) BR112018014522B1 (https=)
CA (1) CA3011661C (https=)
WO (1) WO2017124104A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12019041B2 (en) 2018-11-20 2024-06-25 Xatek, Inc. Portable dielectric spectroscopy device

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6936235B2 (ja) * 2016-01-15 2021-09-15 ケース ウエスタン リザーブ ユニバーシティ サンプル特性評価のための誘電感知
US11275036B2 (en) * 2016-12-09 2022-03-15 Nanyang Technological University Non-destructive testing methods and apparatus
US11016075B2 (en) * 2017-07-20 2021-05-25 Saudi Arabian Oil Company Methods and systems for characterization of geochemical properties of hydrocarbons using microwaves
WO2019023646A2 (en) * 2017-07-27 2019-01-31 Maxim Integrated Products, Inc. ANALYTE SENSOR HOUSING AND METHOD FOR ANALYZING FLUID SAMPLES
JP7173731B2 (ja) * 2017-12-15 2022-11-16 株式会社 堀場アドバンスドテクノ 電磁気センサ
JP7230429B2 (ja) * 2018-10-25 2023-03-01 ソニーグループ株式会社 血小板凝集能解析装置、血小板凝集能解析方法及び血小板凝集能解析システム
EP3884271B1 (en) * 2018-11-20 2023-08-30 Xatek, Inc. Dielectric spectroscopy sensing apparatus and method of use
US11408844B2 (en) * 2019-04-02 2022-08-09 Case Western Reserve University Dielectric sensing to characterize hemostatic dysfunction
US11774388B2 (en) 2019-04-02 2023-10-03 Case Western Reserve University Dielectric sensing to characterize hemostatic dysfunction
CN112294296A (zh) * 2019-08-02 2021-02-02 永健生技医疗器材有限公司 非侵入性血糖测试机系统及方法
CA3147705A1 (en) * 2019-08-29 2021-03-04 Cynthia Kutchko Radio frequency signaling system and curable composition
CN111289583A (zh) * 2020-02-19 2020-06-16 华北电力大学 一种凝胶类材料宽频介电特性的测试装置及方法
EP3940377A1 (en) 2020-07-16 2022-01-19 3M Innovative Properties Company Method, data set and sensor to sense a property of a liquid
DE102021204570A1 (de) 2021-05-06 2022-11-10 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung eingetragener Verein Dosierkopf und Fluidiksystem zur Aufnahme und Dosierung wenigstens eines Mediums
JP7680695B2 (ja) * 2022-01-06 2025-05-21 日本電信電話株式会社 誘電分光センサ
GB2621856B (en) * 2022-08-24 2025-01-08 Africa New Energies Ltd Fluid monitoring
CN120380596A (zh) * 2022-12-22 2025-07-25 深圳华大智造科技股份有限公司 感测系统、芯片封装结构、测序载片及测序方法
US12498341B2 (en) * 2023-09-29 2025-12-16 L'oreal Electronicless accessory recognition using dielectric properties

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5389218A (en) * 1989-01-24 1995-02-14 Gas Research Institute Process for operating a solid-state oxygen microsensor
CN102498201A (zh) * 2009-05-12 2012-06-13 D·伟昌·苏 用于分析和识别分子的方法与装置
CN102680523A (zh) * 2011-03-17 2012-09-19 索尼公司 凝血系统分析方法和凝血系统分析设备
CN103329081A (zh) * 2010-12-09 2013-09-25 阿尔·祺福 用于流体样本分析的微流控装置
CN103712600A (zh) * 2012-10-08 2014-04-09 硕英股份有限公司 液体电容式倾斜微传感器
CN104668003A (zh) * 2015-01-20 2015-06-03 天津农学院 微流控芯片
CN105117085A (zh) * 2015-09-07 2015-12-02 武汉华星光电技术有限公司 内嵌式触控面板及其制造方法

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4686857A (en) 1983-03-04 1987-08-18 Kabushiki Kaisha Toyota Chuo Kenkyusho Method and apparatus for evaluating the performance of dielectric substances
US4765179A (en) * 1985-09-09 1988-08-23 Solid State Farms, Inc. Radio frequency spectroscopy apparatus and method using multiple frequency waveforms
US4884457A (en) 1987-09-30 1989-12-05 Texaco Inc. Means and method for monitoring the flow of a multi-phase petroleum stream
US5042299A (en) 1990-07-23 1991-08-27 Iimorrow, Inc. Capacitive fluid level sensor
US6467358B1 (en) 1997-10-22 2002-10-22 Japan National Oil Corp. Method of measuring flow rates of respective fluids constituting multiphase fluid and flow meter for multiphase flow utilizing same
US6255954B1 (en) 1999-01-29 2001-07-03 Reid Asset Management Company Detection of wear-particles and other impurities in industrial or other fluids
US6362632B1 (en) 2000-05-24 2002-03-26 Becs Technology, Inc. Balanced charge pump capacitive material sensor
GB0030929D0 (en) * 2000-12-19 2001-01-31 Inverness Medical Ltd Analyte measurement
CA2462341C (en) 2001-10-12 2010-12-14 Wisconsin Alumni Research Foundation Microwave dielectric spectroscopy method and apparatus for assays of proteins and other biological molecules
US7291310B2 (en) * 2002-12-17 2007-11-06 The Regents Of The University Of Michigan Microsystem for determining clotting time of blood and low-cost, single-use device for use therein
US6945116B2 (en) * 2003-03-19 2005-09-20 California Institute Of Technology Integrated capacitive microfluidic sensors method and apparatus
US6922064B2 (en) 2003-06-18 2005-07-26 General Motors Corporation Fluid quality test method based on impedance
US20080063566A1 (en) * 2004-09-03 2008-03-13 Mitsubishi Chemical Corporation Sensor Unit and Reaction Field Cell Unit and Analyzer
US7541004B2 (en) * 2004-11-12 2009-06-02 Predict, Inc. MEMS-based sensor for lubricant analysis
USD558086S1 (en) 2005-10-14 2007-12-25 Diana Kathryne Herber Heirloom balloon
BRPI0812391A2 (pt) * 2007-06-20 2015-11-24 Mec Dynamics Corp cartucho e método de determinação do tempo de coagulação do sangue
TWI516601B (zh) 2007-10-26 2016-01-11 環球生物醫療感測器私人有限公司 電化學檢測之裝置及方法
US8578761B2 (en) 2008-03-26 2013-11-12 Denso Corporation Concentration sensor device and concentration detecting method
JP5691168B2 (ja) * 2009-01-08 2015-04-01 ソニー株式会社 血液凝固系解析装置、血液凝固系解析方法及びプログラム
WO2010109317A1 (en) 2009-03-26 2010-09-30 Pricol Limited Capacitive measurement of fuel level and dielectric constant
US8281655B2 (en) 2009-04-03 2012-10-09 Eaton Corporation Fuel gauging system utilizing a digital fuel gauging probe
WO2010138127A1 (en) 2009-05-29 2010-12-02 University Of Miami Solid-state electrochemical sensor
US20110234240A1 (en) * 2010-03-23 2011-09-29 Empire Technology Development, Llc Monitoring dehydration using rf dielectric resonator oscillator
KR101663010B1 (ko) 2010-11-09 2016-10-06 삼성전자주식회사 Ｒｆ용 매칭 세그먼트 회로 및 이를 이용한 ｒｆ통합 소자
US8776246B2 (en) 2011-03-11 2014-07-08 Abbott Point Of Care, Inc. Systems, methods and analyzers for establishing a secure wireless network in point of care testing
US9597149B2 (en) 2011-11-04 2017-03-21 Iogyn, Inc. Tissue extraction devices and methods
US9194859B2 (en) 2011-12-23 2015-11-24 Abbott Point Of Care Inc. Reader devices for optical and electrochemical test devices
US9539389B2 (en) 2012-02-08 2017-01-10 Stmicroelectronics, Inc. Wireless flow sensor using present flow rate data
US8884771B2 (en) 2012-08-01 2014-11-11 Microchip Technology Incorporated Smoke detection using change in permittivity of capacitor air dielectric
US20140114592A1 (en) 2012-10-22 2014-04-24 Custom Electronics, Inc. Operational monitoring of electrochemical capacitors
CN104919309A (zh) 2013-01-18 2015-09-16 索尼公司 电气特性测量装置
EP2975387B1 (en) 2013-03-13 2021-03-31 Sony Corporation Device for analyzing condition of blood, system for analyzing condition of blood, and program for analyzing condition of blood
US9995701B2 (en) 2014-06-02 2018-06-12 Case Western Reserve University Capacitive sensing apparatuses, systems and methods of making same
EP4109095A1 (en) 2014-09-09 2022-12-28 Perosphere Technologies Inc. Microfluid chip-based, universal coagulation assay
JP6936235B2 (ja) * 2016-01-15 2021-09-15 ケース ウエスタン リザーブ ユニバーシティ サンプル特性評価のための誘電感知

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5389218A (en) * 1989-01-24 1995-02-14 Gas Research Institute Process for operating a solid-state oxygen microsensor
CN102498201A (zh) * 2009-05-12 2012-06-13 D·伟昌·苏 用于分析和识别分子的方法与装置
CN103329081A (zh) * 2010-12-09 2013-09-25 阿尔·祺福 用于流体样本分析的微流控装置
CN102680523A (zh) * 2011-03-17 2012-09-19 索尼公司 凝血系统分析方法和凝血系统分析设备
CN103712600A (zh) * 2012-10-08 2014-04-09 硕英股份有限公司 液体电容式倾斜微传感器
CN104668003A (zh) * 2015-01-20 2015-06-03 天津农学院 微流控芯片
CN105117085A (zh) * 2015-09-07 2015-12-02 武汉华星光电技术有限公司 内嵌式触控面板及其制造方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Monitoring Time Course of Human Whole Blood Coagulation Using;Debnath Maji 等;《37th Annual International Conference of the IEEE-Engineering-in-Medicine-and-Biology-Society (EMBC) 会议》;20150831;全文 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12019041B2 (en) 2018-11-20 2024-06-25 Xatek, Inc. Portable dielectric spectroscopy device

Also Published As

Publication number Publication date
EP3403080A4 (en) 2019-09-04
US20200405173A1 (en) 2020-12-31
US11058316B2 (en) 2021-07-13
WO2017124104A1 (en) 2017-07-20
US20190029555A1 (en) 2019-01-31
JP6936235B2 (ja) 2021-09-15
BR112018014522B1 (pt) 2023-05-09
BR112018014522A8 (pt) 2023-05-02
EP3403080A1 (en) 2018-11-21
CA3011661C (en) 2024-04-02
KR20180103944A (ko) 2018-09-19
CA3011661A1 (en) 2017-07-20
JP2019505792A (ja) 2019-02-28
KR102810749B1 (ko) 2025-05-21
BR112018014522A2 (pt) 2019-01-15
CN108780056A (zh) 2018-11-09
AU2017207027B2 (en) 2021-11-18
US10674931B2 (en) 2020-06-09
EP3403080B1 (en) 2025-07-23
AU2017207027A1 (en) 2018-08-16

Similar Documents

Publication Publication Date Title
CN108780056B (zh) 用于样品表征的介电感测
Mondal et al. Microwave assisted non-invasive microfluidic biosensor for monitoring glucose concentration
Feng et al. A microfluidic device integrating impedance flow cytometry and electric impedance spectroscopy for high-efficiency single-cell electrical property measurement
Maji et al. ClotChip: A microfluidic dielectric sensor for point-of-care assessment of hemostasis
ES2804799T3 (es) Aparato y método para medir la cinética de unión y concentración con un sensor resonador
JP2016505850A (ja) 流体を分析するためのシステム
CN102818822B (zh) 利用分析样本中电抗变化以测量凝血酶原时间及血球容积比(hct%)的诊断装置及方法
US20130252319A1 (en) Biosensor for measuring stress based on eletrical device and measurement method thereof, and emotion-on-a-chip and measuring apparatus thereof
TW201202705A (en) Device and method for measuring prothrombin time and hematocrit by analyzing change in reactance in a sample
EP0630471A1 (en) Apparatus for determining the physical and/or chemical properties of a sample, particularly of blood
US11175252B2 (en) Dielectric sensing for blood characterization
Maji et al. Monitoring time course of human whole blood coagulation using a microfluidic dielectric sensor with a 3D capacitive structure
Punter-Villagrasa et al. Toward an anemia early detection device based on 50-μL whole blood sample
Sherif et al. Integration of tri-polar microelectrodes for performance enhancement of an impedance biosensor
US12072310B2 (en) Dielectric sensing to characterize properties of a sample under test
US11408844B2 (en) Dielectric sensing to characterize hemostatic dysfunction
Maji et al. A PMMA microfluidic dielectric sensor for blood coagulation monitoring at the point-of-care
Delianides et al. A multichannel miniaturized dielectric blood coagulometer for point-of-care assessment of hemostasis
Jao et al. Electrical characterization of single cell in microfluidic device
SE521208C2 (sv) System och förfarande för blodanalys
Shahri Microwave-based microfluidic biosensors: from the design and implementation to real-time sensing.
US20250264452A1 (en) A system for in-vitro determination of a parameter of a sample
Zhao et al. Integrated microfluidic multiple electrode aggregometry for point-of-care platelet function analysis
Potti et al. Conformal Microwave Sensor for Noninvasive Sweat Analysis to Predict Electrolyte Imbalances: P. Devisowjanya et al.
EP3578973A1 (en) A method for evaluation of the oxidative stress in biological samples and device for achieving such method

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant