CN108743976B - 基于低-z原子的肠ct造影材料 - Google Patents

基于低-z原子的肠ct造影材料 Download PDF

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CN108743976B
CN108743976B CN201810611475.2A CN201810611475A CN108743976B CN 108743976 B CN108743976 B CN 108743976B CN 201810611475 A CN201810611475 A CN 201810611475A CN 108743976 B CN108743976 B CN 108743976B
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contrast
contrast material
materials
poly
particles
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CN108743976A (zh
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B·M·耶
付雁军
T·德塞
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University of California San Diego UCSD
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University of California San Diego UCSD
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0409—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is not a halogenated organic compound
    • A61K49/0414—Particles, beads, capsules or spheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0409—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is not a halogenated organic compound
    • A61K49/0414—Particles, beads, capsules or spheres
    • A61K49/0419—Microparticles, microbeads, microcapsules, microspheres, i.e. having a size or diameter higher or equal to 1 micrometer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461—Dispersions, colloids, emulsions or suspensions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computed tomography [CT]
    • A61B6/032—Transmission computed tomography [CT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/48—Diagnostic techniques
    • A61B6/481—Diagnostic techniques involving the use of contrast agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Pulmonology (AREA)
  • Theoretical Computer Science (AREA)
CN201810611475.2A 2013-03-15 2014-03-17 基于低-z原子的肠ct造影材料 Active CN108743976B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361790734P 2013-03-15 2013-03-15
US201361798392P 2013-03-15 2013-03-15
US61/790,734 2013-03-15
US61/798,392 2013-03-15
CN201480022822.8A CN105142680A (zh) 2013-03-15 2014-03-17 基于低-z原子的肠ct造影材料

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CN108743976A CN108743976A (zh) 2018-11-06
CN108743976B true CN108743976B (zh) 2021-10-29

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CN201480022822.8A Pending CN105142680A (zh) 2013-03-15 2014-03-17 基于低-z原子的肠ct造影材料

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US (1) US11033640B2 (https=)
EP (2) EP3984560A1 (https=)
JP (3) JP2016516072A (https=)
CN (2) CN108743976B (https=)
ES (1) ES2897624T3 (https=)
WO (1) WO2014145509A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11033640B2 (en) 2013-03-15 2021-06-15 The Regents Of The University Of California Enteric CT contrast material based on low-z atoms
US20160193366A1 (en) 2013-08-16 2016-07-07 The Regents Of The University Of California Silicone-based enteric ct contrast material
EP3960159A1 (en) 2015-04-20 2022-03-02 The Regents of the University of California Encapsulated gas or partial vacuum ct contrast material
WO2017223343A1 (en) * 2016-06-22 2017-12-28 Board Of Regents, The University Of Texas System Contrast agents and methods of making the same for spectral ct that exhibit cloaking and auto-segmentation
CN110382010A (zh) 2016-12-08 2019-10-25 布里格姆妇女医院 铋-钆纳米颗粒
CN109100775B (zh) * 2018-07-06 2020-05-29 郑州云海信息技术有限公司 一种双层探测器的能量谱校正方法与装置
JP2020103571A (ja) * 2018-12-27 2020-07-09 キヤノンメディカルシステムズ株式会社 医用処理装置及びｘ線診断システム
WO2022235830A1 (en) * 2021-05-05 2022-11-10 The Regents Of The University Of California Low x-ray attenuation change hard shelled oral contrast material
WO2024086131A1 (en) * 2022-10-18 2024-04-25 The Johns Hopkins University Systems and methods for angiography using multi-energy detectors

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US3592185A (en) * 1967-04-18 1971-07-13 Yeda Res & Dev Ferromagnetic contrast media and method of use
WO1992017514A1 (en) * 1991-04-05 1992-10-15 Unger Evan C Low density microspheres and their use as contrast agents for computed tomography
CN1215342A (zh) * 1996-02-20 1999-04-28 耐克麦德英梅金公司 造影剂
CN1303273A (zh) * 1998-04-09 2001-07-11 奈科姆成像有限公司 微粒造影剂在研究生理参数的诊断成像中的应用
EP2127682A1 (en) * 2008-05-28 2009-12-02 Deutsches Krebsforschungszentrum X-ray contrast agent based on bismuth oxide-nanoparticles

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JPS6238172A (ja) 1985-08-12 1987-02-19 株式会社　高研 抗血栓性医用材料の製造方法
DE3709851A1 (de) * 1987-03-24 1988-10-06 Silica Gel Gmbh Adsorptions Te Nmr-diagnostische fluessigkeitszusammensetzungen
IL82834A (en) 1987-06-09 1990-11-05 Yissum Res Dev Co Biodegradable polymeric materials based on polyether glycols,processes for the preparation thereof and surgical artiicles made therefrom
GB9006671D0 (en) 1990-03-24 1990-05-23 Univ Manchester Diagnostic method and compositions
SE9101709L (sv) * 1991-06-03 1992-12-04 Karlshamns Lipidteknik Ab Lipidderivat som diagnostikum eller kontrastmedel
US5323780A (en) 1992-08-07 1994-06-28 University Of Florida Research Foundation, Inc. Artifact-free imaging contrast agent
US5318769A (en) 1993-03-31 1994-06-07 Sterling Winthrop Inc. Compositions of iodophenyl esters for X-ray visualization of the gastrointestinal tract
US5472682A (en) 1993-03-31 1995-12-05 Sterling Winthrop Inc. Compositions of iodophenyl esters and iodophenyl sulfonates and pharmaceutically acceptable clays for visualization of the gastrointestinal tract
CA2184089A1 (en) 1994-02-25 1995-08-31 Carl R. Illig X-ray contrast compositions containing cellulose derivatives
JPH09512029A (ja) 1994-04-21 1997-12-02 ニコメド イマギング アクスイェ セルスカプ 薬理学的に許容される粘土を含むｘ線造影組成物
US5736121A (en) 1994-05-23 1998-04-07 Imarx Pharmaceutical Corp. Stabilized homogenous suspensions as computed tomography contrast agents
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US20160193366A1 (en) 2013-08-16 2016-07-07 The Regents Of The University Of California Silicone-based enteric ct contrast material

Patent Citations (5)

* Cited by examiner, † Cited by third party
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US3592185A (en) * 1967-04-18 1971-07-13 Yeda Res & Dev Ferromagnetic contrast media and method of use
WO1992017514A1 (en) * 1991-04-05 1992-10-15 Unger Evan C Low density microspheres and their use as contrast agents for computed tomography
CN1215342A (zh) * 1996-02-20 1999-04-28 耐克麦德英梅金公司 造影剂
CN1303273A (zh) * 1998-04-09 2001-07-11 奈科姆成像有限公司 微粒造影剂在研究生理参数的诊断成像中的应用
EP2127682A1 (en) * 2008-05-28 2009-12-02 Deutsches Krebsforschungszentrum X-ray contrast agent based on bismuth oxide-nanoparticles

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Publication number Publication date
CN105142680A (zh) 2015-12-09
JP2020193223A (ja) 2020-12-03
EP2968619A1 (en) 2016-01-20
JP2016516072A (ja) 2016-06-02
EP2968619B1 (en) 2021-08-11
JP2018090624A (ja) 2018-06-14
US11033640B2 (en) 2021-06-15
EP2968619A4 (en) 2016-11-02
WO2014145509A1 (en) 2014-09-18
CN108743976A (zh) 2018-11-06
ES2897624T3 (es) 2022-03-02
US20140276021A1 (en) 2014-09-18
EP3984560A1 (en) 2022-04-20
JP6843787B2 (ja) 2021-03-17

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