CN108740361B - Coated multivitamin and preparation method and application thereof - Google Patents
Coated multivitamin and preparation method and application thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/174—Vitamins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/105—Aliphatic or alicyclic compounds
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/179—Colouring agents, e.g. pigmenting or dyeing agents
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
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Abstract
The invention relates to a coated multivitamin and a preparation method and application thereof, wherein the coated multivitamin comprises the following components in parts by weight: 11-2 parts of vitamin B, 21-2 parts of vitamin B, 62-4 parts of vitamin B, 120.5-1.5 parts of vitamin B, 20-35 parts of vitamin C, 301-5 parts of povidone K, 1-10 parts of coating agent and 0-100 parts of corn starch; and (2) component: 0.8-2 parts of methionine, 1-2 parts of leucine, 0.5-1.5 parts of arginine, 1-2 parts of lysine, 1.2-2 parts of threonine, 1-2 parts of valine, 301-5 parts of povidone K, 1-10 parts of lemon yellow and 0-100 parts of corn starch; and (3) component: 2-3 parts of vitamin A, 31-1.8 parts of vitamin D, 3-4 parts of vitamin E, 31.2-2 parts of vitamin K, 301-5 parts of povidone K, 1-10 parts of coating agent and 0-100 parts of corn starch. The coating compound vitamin has various components which are compatible with each other, so that the nutrition is comprehensive and the effect is enhanced; can effectively improve the immunity of the livestock and poultry and promote the growth of the livestock and poultry.
Description
Technical Field
The invention relates to a coated multivitamin and a preparation method and application thereof.
Background
Vitamins are a kind of trace organic substances which must be obtained from food for human and animals to maintain normal physiological functions, and play an important role in the growth, metabolism and development processes of human bodies.
During the feeding process of animals such as pigs, cattle, sheep and the like, corresponding vitamins need to be supplemented in different growth periods so as to improve the health state of the animals; effectively improving the digestive system, quickly supplementing beneficial bacteria, inhibiting the proliferation of harmful bacteria and regulating the ecological balance of intestinal flora; reducing or replacing feed antibiotics and reducing drug resistance; enhancing the non-specific immunity of animals, reducing the morbidity by more than 60 percent and the like.
The growth effect of the animals is different when the vitamins are supplemented, the amount of the supplemented vitamins is different, and the proportion of the supplement types is different. The existing vitamin complex is only a simple mixture of several simple vitamins and added carriers. The pig is mixed with feed and drinking water for use, and has poor stability and low bioavailability.
Disclosure of Invention
The first objective of the present invention is to provide a coated vitamin complex, wherein the vitamin B complex, vitamin C and fat-soluble vitamin are granulated and coated respectively, so as to improve the stability of these vitamins against light, heat and oxygen, and have sustained release effect and correspondingly improved bioavailability.
The coated multivitamin comprises the following components 1-3 in parts by weight of 1-2:
component 1: 11-2 parts of vitamin B, 21-2 parts of vitamin B, 62-4 parts of vitamin B, 120.5-1.5 parts of vitamin B, 20-35 parts of vitamin C, 301-5 parts of povidone K, 1-10 parts of coating agent and 0-100 parts of corn starch;
and (2) component: 0.8-2 parts of methionine, 1-2 parts of leucine, 0.5-1.5 parts of arginine, 1-2 parts of lysine, 1.2-2 parts of threonine, 1-2 parts of valine, 301-5 parts of povidone K, 1-10 parts of lemon yellow and 0-100 parts of corn starch;
and (3) component: the coating comprises, by weight, 2-3 parts of vitamin A, 31-1.8 parts of vitamin D, 3-4 parts of vitamin E, 31.2-2 parts of vitamin K, 301-5 parts of povidone K, 1-10 parts of a coating agent and 0-100 parts of corn starch.
The three components are mutually compatible for use, so that the utilization rate and the absorption rate of the coated multivitamin are effectively improved. Especially when the ratio of the three components is 1:1: 1.
Preferably, the coated multivitamin comprises the following components 1-3 in parts by weight in a ratio of 1:1: 1:
component 1: 11.1-1.3 parts of vitamin B, 21.5-1.7 parts of vitamin B, 62.3-2.5 parts of vitamin B, 120.9-1 parts of vitamin B, 27-31 parts of vitamin C, 303-5 parts of povidone K, 4-6 parts of coating agent and 50-70 parts of corn starch;
And (2) component: 1.1-1.5 parts of methionine, 1.2-1.6 parts of leucine, 0.8-1.0 part of arginine, 1.3-1.7 parts of lysine, 1.4-1.8 parts of threonine, 1.2-1.6 parts of valine, 303-5 parts of povidone K, 0.2-0.6 part of lemon yellow and 80-95 parts of corn starch;
and (3) component: 2.1-2.5 parts of vitamin A, 31.1-1.5 parts of vitamin D, 3.5-3.9 parts of vitamin E, 31.5-1.9 parts of vitamin K, 303-5 parts of povidone K, 4-6 parts of coating agent and 70-90 parts of corn starch.
The invention provides a preferable scheme, and the coated multivitamin comprises the following components 1-3 in parts by weight in a ratio of 1:1: 1:
component 1: 11.2 parts of vitamin B, 21.6 parts of vitamin B, 62.4 parts of vitamin B, 120.8 parts of vitamin B, 29 parts of vitamin C, 303-5 parts of povidone K, 4-6 parts of coating agent and 50-70 parts of corn starch;
and (2) component: 1.3 parts of methionine, 1.4 parts of leucine, 0.9 part of arginine, 1.5 parts of lysine, 1.6 parts of threonine, 1.4 parts of valine, 303-5 parts of povidone K, 0.2-0.6 part of lemon yellow and 80-95 parts of corn starch;
and (3) component: 2.3 parts of vitamin A, 31.3 parts of vitamin D, 3.7 parts of vitamin E, 31.7 parts of vitamin K, 303-5 parts of povidone K, 4-6 parts of coating agent and 70-90 parts of corn starch.
The second objective of the invention is to provide a preparation method of the coated multivitamin,
wherein the preparation of the component 1 specifically comprises the following steps: taking 40-60% of corn starch, adding vitamin B1, vitamin B2, vitamin B6, vitamin B12 and vitamin C into the corn starch, adding the rest of corn starch, fully mixing, adding povidone K30, and fully and uniformly mixing; granulating, drying, and sieving with a 20-100-mesh sieve; adding coating agent, and coating.
The method specifically comprises the following steps: adding vitamin B1, vitamin B2, vitamin B6, vitamin B12 and vitamin C into 40-60% of corn starch, adding the rest of corn starch, and stirring at the speed of 20-30 r/min for 5-15 minutes; adding 0.2-0.4 times of purified water for dilution, adding povidone K30, and stirring at the speed of 20-30 r/min for 25-35 minutes; after wet granulation, drying at 50-60 ℃ for 50-70 min, and sieving with a 20-100-mesh sieve; and adding a coating agent, coating at the temperature of 35-45 ℃, and drying to obtain the coating.
Wherein 0.2-0.4 time of purified water is relative to the weight of dry powder, and the dry powder comprises the total weight of vitamin B1, vitamin B2, vitamin B6, vitamin B12, vitamin C and corn starch.
Wherein the preparation of the component 2 specifically comprises the following steps: adding 40-60% of corn starch, adding methionine, leucine, arginine, lysine, threonine and valine, adding the rest of corn starch, fully mixing, adding water for dilution, adding povidone K30 and lemon yellow, and fully and uniformly mixing; granulating and drying to obtain the finished product.
Wherein, the preparation of the component 3 specifically comprises the following steps: adding 40-60% of corn starch, adding vitamin A, vitamin D3, vitamin E and vitamin K3, adding the rest of corn starch, fully mixing, adding water for dilution, adding povidone K30, and fully and uniformly mixing; granulating, drying, and sieving with a 20-100-mesh sieve; adding coating agent, and coating.
The coated multivitamin is applied to livestock and poultry breeding. The coated multivitamins can effectively improve the immunity of livestock and poultry and promote the growth of the livestock and poultry.
During the growth process of pigs, various stresses are too large and nutrition is unbalanced, so that the pigs cannot fully exert genetic potential, and the benefit of a pig farm is seriously influenced. The coated compound vitamin has particularly remarkable effect in the aspect of application to pigs. Especially providing a comprehensive and high-quality nutritional supplement for pigs in the fattening period.
In the feeding process, the components 1, 2 and 3 are mixed according to the proportion of 1: 1: 1, proportioning, mixing into feed and feeding.
Specifically, the coating compound vitamin of the invention has different addition amounts to piglets, replacement/gestation sows, lactating sows, multiparous sows in nonpregnant period and breeding boars.
The specific addition amount per day is as follows:
1) the process of meat-increasing feeding in the continuous period: adding 280-320 g of the coated multivitamins into each ton of feed;
2) replacement/pregnant sow feeding process: 480-520 g of the coated compound vitamin is added into each ton of feed;
3) the feeding process of the sows in the lactation period comprises the following steps: in summer, 950-1050 g of the coated composite vitamin is added into each ton of feed; 480-520 g of the feed is added into each ton of the feed in other seasons;
4) the non-pregnant feeding process of the multiparous sows: adding 950-1050 g of the coated compound vitamin into each ton of feed;
5) the breeding boar feeding process comprises the following steps: adding 950-1050 g of the coated compound vitamin into each ton of feed; when the mating is frequent, 5 grams of the additive is added every day.
The coating compound vitamin provided by the invention has the advantages that various components are compatible with each other, and the nutrition is comprehensive and synergistic. In addition, the invention respectively granulates and coats firstly, thereby avoiding the damage of the vitamin by light, heat and oxygen, avoiding the interaction between the vitamin and amino acid, ensuring that the potency of the vitamin is not damaged and the effective components are complete.
Detailed Description
The following examples are intended to illustrate the invention but are not intended to limit the scope of the invention.
Example 1
The embodiment provides a coated multivitamin which comprises the following components 1:1:1 and 1-3:
component 1: 11.2 parts of vitamin B, 21.6 parts of vitamin B, 62.4 parts of vitamin B, 120.8 parts of vitamin B, 29 parts of vitamin C, 304 parts of povidone K, 5 parts of coating agent (red) and 58 parts of corn starch;
and (2) component: 1.3 parts of methionine, 1.4 parts of leucine, 0.9 part of arginine, 1.5 parts of lysine, 1.6 parts of threonine, 1.4 parts of valine, 304.5 parts of povidone K, 0.4 part of lemon yellow and 89 parts of corn starch;
and (3) component: 2.3 parts of vitamin A, 31.3 parts of vitamin D, 3.7 parts of vitamin E, 31.7 parts of vitamin K, 304 parts of povidone K, 4-6 parts of coating agent (green) and 84 parts of corn starch.
Example 2
The embodiment provides a coated multivitamin which comprises the following components 1:1:1 and 1-3:
component 1: 11.5 parts of vitamin B, 21.4 parts of vitamin B, 62.5 parts of vitamin B, 120.8 parts of vitamin B, 29 parts of vitamin C, 304 parts of povidone K, 5 parts of coating agent (red) and 58 parts of corn starch;
and (2) component: 1.4 parts of methionine, 1.3 parts of leucine, 0.9 part of arginine, 1.5 parts of lysine, 1.6 parts of threonine, 1.4 parts of valine, 304.5 parts of povidone K, 0.4 part of lemon yellow and 89 parts of corn starch;
And (3) component: 2.3 parts of vitamin A, 31.3 parts of vitamin D, 3.7 parts of vitamin E, 31.7 parts of vitamin K, 304 parts of povidone K, 4-6 parts of coating agent (green) and 84 parts of corn starch.
Example 3
The embodiment provides a coated multivitamin which comprises the following components 1:1:1 and 1-3:
component 1: 11.2 parts of vitamin B, 21.6 parts of vitamin B, 62.4 parts of vitamin B, 120.9 parts of vitamin B, 29 parts of vitamin C, 304 parts of povidone K, 5 parts of coating agent (red) and 58 parts of corn starch;
and (2) component: 1.3 parts of methionine, 1.4 parts of leucine, 0.9 part of arginine, 1.5 parts of lysine, 1.5 parts of threonine, 1.4 parts of valine, 304.5 parts of povidone K, 0.4 part of lemon yellow and 89 parts of corn starch;
and (3) component: 2.3 parts of vitamin A, 31.3 parts of vitamin D, 3.7 parts of vitamin E, 31.7 parts of vitamin K, 304 parts of povidone K, 4-6 parts of coating agent (green) and 84 parts of corn starch.
Example 4
Component 1: 11.5 parts of vitamin B, 21.5 parts of vitamin B, 62.1 parts of vitamin B, 120.9 parts of vitamin B, 31 parts of vitamin C, 304 parts of povidone K, 5 parts of coating agent (red) and 56 parts of corn starch;
and (2) component: 1.3 parts of methionine, 1.4 parts of leucine, 0.9 part of arginine, 1.5 parts of lysine, 1.5 parts of threonine, 1.2 parts of valine, 304.5 parts of povidone K, 0.4 part of lemon yellow and 80 parts of corn starch;
And (3) component: 2.3 parts of vitamin A, 31.3 parts of vitamin D, 3.7 parts of vitamin E, 31.7 parts of vitamin K, 304 parts of povidone K, 4-6 parts of coating agent (green) and 84 parts of corn starch.
Example 5
Component 1: 11.2 parts of vitamin B, 21.9 parts of vitamin B, 62.2 parts of vitamin B, 121.9 parts of vitamin B, 28 parts of vitamin C, 304 parts of povidone K, 5 parts of coating agent (red) and 56 parts of corn starch;
and (2) component: 1.3 parts of methionine, 1.4 parts of leucine, 0.9 part of arginine, 1.4 parts of lysine, 1.5 parts of threonine, 1.2 parts of valine, 304.5 parts of povidone K, 0.4 part of lemon yellow and 80 parts of corn starch;
and (3) component: 2.0 parts of vitamin A, 31.2 parts of vitamin D, 3.7 parts of vitamin E, 31.7 parts of vitamin K, 304 parts of povidone K, 4-6 parts of coating agent (green) and 84 parts of corn starch.
Example 6
The embodiment provides a preparation method of the component 1 in the coated multivitamin provided in the embodiment 1-5, which specifically comprises the following steps:
1. mixing: adding 50% corn starch, vitamin B1, vitamin B2, vitamin B6, vitamin B12 and vitamin C, adding the rest corn starch, mixing and stirring for 10 min.
And (3) diluting the dissolved povidone K30 by 0.2-0.4 time of purified water, slowly adding the dissolved povidone K30 into a trough type mixer, stirring while adding at the rotating speed of 24r/min, and mixing and stirring for 30 minutes.
2. Granulating and rounding: carrying out wet granulation on the mixed material in an E-100C axial double-screw spherical extruder to extrude a full strip material; rounding on S-700 rounding machine to obtain good round degree of the pill, and making preparation for next coating.
3. And (3) drying: the spheronized pellets were removed and dried in a WBF-200 fluidized bed system (top-blown) for 1 hour.
4. Sieving: the dried granules were placed in a vibrating sieve and sieved, leaving granules of 24 mesh size.
5. Coating and drying: the sieved granules were placed in a WBF-200 fluidized bed system (bottom-spray), and the red coating agent diluted with purified water and mixed uniformly was slowly introduced into the fluidized bed by a peristaltic pump and coated at a temperature of 40 ℃. And dried at 55 c for 1.5 hours. And (6) detecting the semi-finished product to be qualified, and warehousing.
Example 7
The embodiment provides a preparation method of the component 2 in the coated multivitamin provided in the embodiment 1 to 5, which comprises the following specific steps:
1. mixing: adding 50% corn starch, methionine, leucine, arginine, lysine, threonine and valine, and adding the rest corn starch, mixing and stirring for 10 min.
Dissolving polyvidone K30 in 18 parts of purified water, adding lemon yellow, and mixing; slowly adding into a trough type mixing machine while stirring, and mixing and stirring for 30 minutes.
2. Granulating and rounding: carrying out wet granulation on the mixed material in an E-100C axial double-screw spherical extruder to extrude a full strip material; the plain pills are rounded on an S-700 type rounding machine, so that the rounding degree of the plain pills is good.
3. And (3) drying: the spheronized pellets were removed and dried in a fluid bed system model WBF-200 (top-blown) for 1 hour.
4. Sieving: the dried granules were placed in a vibrating sieve and sieved, leaving granules of 24 mesh size. And (6) detecting the semi-finished product to be qualified, and warehousing.
Example 8
The embodiment provides a preparation method of the component 3 in the coated multivitamin provided in the embodiment 1-5, which specifically comprises the following steps:
1. mixing: adding 48% corn starch, vitamin A, vitamin D3, vitamin E and vitamin K3, and adding the rest corn starch, mixing and stirring for 10 min.
Povidone K30 diluted and dissolved with purified water was slowly added to a tank mixer while stirring, and the mixture was stirred for 30 minutes.
2. Granulating and rounding: carrying out wet granulation on the mixed material in an E-100C axial double-screw spherical extruder to extrude a round strip material; rounding on S-700 rounding machine to obtain good rounding degree, and making preparation for next coating.
3. And (3) drying: the spheronized pellets were removed and dried in a fluid bed system model WBF-200 (top-blown) for 1 hour.
4. Sieving: the dried granules were placed in a vibrating sieve and sieved, leaving granules of 24 mesh size.
5. Coating and drying: the sieved granules were placed in a WBF-200 fluidized bed system (bottom spray), and the green coating agent diluted with purified water and mixed well was slowly introduced into the fluidized bed by a peristaltic pump to coat. The coating temperature was set to 40 ℃ and the coating drying time was set to 1.5 hours. And (6) detecting the semi-finished product to be qualified, and warehousing.
Comparative example 1
This comparative example provides a coated multivitamin differing from example 1 only in that component 1 was replaced with taurine;
comparative example 2
This comparative example provides a coated multivitamin which differs from example 1 only in that component 2 is replaced with taurine.
Comparative example 3
This comparative example provides a coated multivitamin which differs from example 1 only in that component 3 is replaced with taurine.
Experimental example 1
Feeding the coated compound vitamins of examples 1-5 and comparative examples 1-3 to pigs, and carrying out test comparison on the pigs; 90 Du-Dachang three-element hybrid pigs of about 30kg are selected for the test, randomly divided into 9 groups, 10 heads in each group, and subjected to a comparative feeding test for 40 days.
Feeding management: the 9 groups of pigs are all fed in a semi-open pigsty, the ration proportion and the nutrition level of the blank group, the comparative group and the example group are completely the same, and the blank group is fed with the basic ration without any additive. Comparative and example groups the coated multivitamins specified above were added at 30 g/100 kg of feed. Recording the consumption condition of each group of feed; meanwhile, the ingestion, the feces and the health condition of the patient are observed. The weight on empty stomach was measured at the beginning and end of the test, respectively.
The coated multivitamins described in comparative examples 1-3 and examples 1-5 were fed for 40 days, and the test results were as follows:
TABLE 1 average daily gain
TABLE 2 feed consumption and feed/weight gain
| Group of | Average daily consumption of the head (kg) | Feed/weight gain |
| Example 1 | 2.01±0.11 | 3.18 |
| Example 2 | 1.98±0.14 | 3.21 |
| Example 3 | 2.02±0.09 | 3.23 |
| Example 4 | 2.02±0.15 | 3.26 |
| Example 5 | 1.99±0.12 | 3.17 |
| Comparative example 1 | 1.97±0.08 | 3.43 |
| Comparative example 2 | 1.91±0.13 | 3.49 |
| Comparative example 3 | 2.01±0.07 | 3.52 |
| Example of blank group | 1.93±0.10 | 3.87 |
It follows that the average daily gain: example > comparative example > blank example; the ratio of the materials to the meat is as follows: example < comparative example < blank group example
Although the invention has been described in detail hereinabove by way of general description, specific embodiments and experiments, it will be apparent to those skilled in the art that many modifications and improvements can be made thereto based on the invention. Accordingly, such modifications and improvements are intended to be within the scope of the invention as claimed.
Claims (2)
1. The coated multivitamin for pigs is characterized by comprising the following components in parts by weight of 1:1:1, 1-3:
component 1: vitamin B11.2 parts of vitamin B21.6 parts of vitamin B62.4 parts of vitamin B120.8 part of vitamin C, 29 parts of vitamin C, 303-5 parts of povidone K, 4-6 parts of coating agent and 50-70 parts of corn starch;
and (2) component: 1.3 parts of methionine, 1.4 parts of leucine, 0.9 part of arginine, 1.5 parts of lysine, 1.6 parts of threonine, 1.4 parts of valine, 303-5 parts of povidone K, 0.2-0.6 part of lemon yellow and 80-95 parts of corn starch;
and (3) component: 2.3 parts of vitamin A and vitamin D31.3 parts of vitamin E3.7 parts of vitamin K31.7 parts of polyvidone K303-5 parts of coating agent, 4-6 parts of corn starch 70-90 parts;
the preparation of the component 1 is specifically as follows: taking 40-60% of corn starch, adding vitamin B into the corn starch1Vitamin B2Vitamin B6Vitamin B12Adding the rest of corn starch after the vitamin C is added, and stirring for 5-15 minutes at the speed of 20-30 r/min; adding 0.2-0.4 times of purified water for dilution, adding povidone K30, and stirring at the speed of 20-30 r/min for 25-35 minutes; after wet granulation, drying at 50-60 ℃ for 50-70 min, and sieving with a 20-100-mesh sieve; adding a coating agent, coating at the temperature of 35-45 ℃, and drying to obtain the coating; the preparation of the component 2 is specifically as follows: adding 40-60% of corn starch, adding methionine, leucine, arginine, lysine, threonine and valine, adding the rest of corn starch, fully mixing, adding water for dilution, adding povidone K30 and lemon yellow, and fully and uniformly mixing; granulating and drying to obtain the finished product; the preparation of the component 3 is specifically as follows: taking 40-60 percent of corn starch, Adding vitamin A and vitamin D into the extract3Vitamin E and vitamin K3Then adding the rest of corn starch, fully mixing, adding water for dilution, adding povidone K30, and fully and uniformly mixing; granulating, drying, and sieving with a 20-100-mesh sieve; diluting with water, adding coating agent, and coating.
2. The method for adding the coated multivitamin for pigs according to claim 1, wherein the amount of the coated multivitamin added to each pig per day is specifically as follows:
1) the process of meat-increasing feeding in the continuous period: adding 280-320 g of the coated multivitamins into each ton of feed;
2) replacement/pregnant sow feeding process: 480-520 g of the coated compound vitamin is added into each ton of feed;
3) the feeding process of the sows in the lactation period comprises the following steps: in summer, 950-1050 g of the coated composite vitamin is added into each ton of feed; 480-520 g of the feed is added into each ton of the feed in other seasons;
4) the non-pregnant feeding process of the multiparous sows: adding 950-1050 g of the coated compound vitamin into each ton of feed;
5) the breeding boar feeding process comprises the following steps: 950-1050 g of the coated compound vitamin is added into each ton of feed.
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| CN110583942B (en) * | 2019-09-12 | 2022-07-29 | 四川博浩达生物科技有限公司 | Solid beverage containing inositol and glutathione |
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