CN108721291A - 一种减少创面渗液、促进伤口愈合的产品 - Google Patents
一种减少创面渗液、促进伤口愈合的产品 Download PDFInfo
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- CN108721291A CN108721291A CN201710370995.4A CN201710370995A CN108721291A CN 108721291 A CN108721291 A CN 108721291A CN 201710370995 A CN201710370995 A CN 201710370995A CN 108721291 A CN108721291 A CN 108721291A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
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Abstract
本发明是一种减少创面渗液、促进伤口和创面愈合的产品(粉剂),本发明涉及医药医疗领域,尤其是一种减少创面渗液、促进伤口愈合的粉剂产品配方及其制备方法。该产品主要通过药粉直接作用于创面(伤口),与渗液组织形成膜性保护作用、与外界建立通透屏障,抑制耐药菌的活性,阻断菌的生长和繁殖,导致细菌死亡。生物结晶糖吸收组织渗液后与药物和杀灭的细菌快速形成结痂,为新生肉芽组织提供良好的生长环境。主要用途:该发明广泛用于陈旧性创面(伤口)、术后切口脂肪液化、皮肤软组织化脓性感染创面(伤口)、褥疮的愈合;最终解决了组织渗液和创面环境问题,为新生肉芽组织提供良好的生存环境。
Description
技术领域
本发明涉及产品配方和医疗领域,尤其是一种减少创面渗液、促进伤口愈合的产品配方及其制备方法。
技术背景
陈旧性创伤(伤口),是指创伤后换药超过7天甚至达数月不能愈合的伤口.这类伤口多伴肉芽组织增生、水肿合并感染而经久不愈。
脂肪液化是手术伤口愈合不良的主要原因之一。特别是切口处脂肪较多并采用电刀手术时,其发生机制可能是由于电刀所产生的高温造成皮下脂肪组织的浅表烧伤及部分脂肪细胞因热损伤发生变性, 同时脂肪组织内毛细血管由于凝固作用而栓塞, 使本身血运较差的肥厚脂肪组织血液供应进一步发生障碍, 术后脂肪组织发生无菌性坏死, 形成较多渗液, 影响切口愈合。
创面化脓性感染常见于烧烫伤创面、物理治疗(激光等)创面、以及皮肤软组织炎症引起的化脓性感染创面。临床常伴随有黄色或透明的组织渗液、以及创面组织坏死等症状,迟迟不能结痂。
以上病例,随着生活水平的提高,和现代医疗技术水平的进步,其发病率逐年增长。在治疗过程中,对其患者的康复心理和医院的住院周转率也有着非常大的影响。目前没有产品直接或间接靶向该领域;也没有产品能够改善其治疗效果、缩短治疗周期。临床常见的治疗方式为通过烤灯物理改善渗液来进行治疗,其效果并不明显。因此,该类产品需求是必须的,为患者减轻心里负担,为医院提高住院周转率。
发明内容
本发明的目的是提供一种具有抗菌消炎,抑制细菌繁殖,减少渗液,干燥创面,去腐生肌,促进伤口愈合的产品。来弥补上述领域治疗的缺陷。
为达到上述目的,本发明的配方组成及份量:喹诺酮10-40份,磺胺4-16份,生物结晶糖5-20份;
一种减少创面渗液、促进伤口愈合的产品,其制备方法是:将上述原料制成微细粉末,混合搅匀即可。
有益效果
本发明所述的一种减少创面渗液、促进伤口愈合的产品,可广泛应用于陈旧性创伤(伤口)、术后脂肪液化、皮肤软组织化脓性感染等创面。
本发明所述的一种减少创面渗液、促进伤口愈合的产品,其组方科学精炼,制备工艺简单,能有效的消炎抗菌,抑制细菌繁殖,干燥创面,减少创面渗液,去腐生肌,促进伤口和创面愈合。安全性高,无毒副作用。
具体实施方式
一种减少创面渗液、促进伤口愈合的产品组方及份量:喹诺酮10份,磺胺4份,生物结晶糖5份;
一种减少创面渗液、促进伤口愈合的产品制备方法,将上述原料药制成微细粉末,同时置入同一搅拌混匀设备,搅拌混匀2小时,抽样检查成分含量比例是否均匀,均匀后再进行最小单位灌装,成品包装,最后成品灭菌处理即出产品。
Claims (1)
1.一种减少创面渗液、促进伤口愈合的产品,其特征在于配方组成及份量:喹诺酮10-40份,磺胺4-16份,生物结晶糖5-20份。
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Citations (1)
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CN1660442A (zh) * | 2004-12-29 | 2005-08-31 | 中国海洋大学 | 含海藻糖和透明质酸的烧伤用药传递系统及其制备方法 |
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Patent Citations (1)
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CN1660442A (zh) * | 2004-12-29 | 2005-08-31 | 中国海洋大学 | 含海藻糖和透明质酸的烧伤用药传递系统及其制备方法 |
Non-Patent Citations (2)
Title |
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SHANTA M. MODAK ET AL.: "Combined Topical Use of Silver Sulfadiazine and Antibiotics as a Possilbe Solution to Bacterial Resistance in Burn Wounds", 《THE JOURNAL OF BURN CARE & REHABILITATION》 * |
孙云霞: "对慢性难愈合伤口使用白砂糖换药的护理探讨", 《航空航天医学杂志》 * |
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