CN108720962A - A kind of syringe for establishing animal encephalic Hemorrhage Model - Google Patents
A kind of syringe for establishing animal encephalic Hemorrhage Model Download PDFInfo
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- CN108720962A CN108720962A CN201810687831.9A CN201810687831A CN108720962A CN 108720962 A CN108720962 A CN 108720962A CN 201810687831 A CN201810687831 A CN 201810687831A CN 108720962 A CN108720962 A CN 108720962A
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- syringe
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- thread
- fixed block
- core
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- 241001465754 Metazoa Species 0.000 title claims abstract description 31
- 208000032843 Hemorrhage Diseases 0.000 title claims abstract description 29
- 238000002347 injection Methods 0.000 claims abstract description 14
- 239000007924 injection Substances 0.000 claims abstract description 14
- 239000011521 glass Substances 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 2
- 238000002474 experimental method Methods 0.000 abstract description 21
- 238000010171 animal model Methods 0.000 abstract description 13
- 239000008280 blood Substances 0.000 abstract description 11
- 210000004369 blood Anatomy 0.000 abstract description 11
- 238000005086 pumping Methods 0.000 abstract description 7
- 238000013461 design Methods 0.000 abstract description 5
- 238000007917 intracranial administration Methods 0.000 abstract description 4
- 238000010276 construction Methods 0.000 abstract description 2
- 201000010099 disease Diseases 0.000 description 12
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 12
- 238000010586 diagram Methods 0.000 description 11
- 230000001105 regulatory effect Effects 0.000 description 7
- 238000011160 research Methods 0.000 description 6
- 238000011161 development Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 208000019553 vascular disease Diseases 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 2
- 206010018985 Haemorrhage intracranial Diseases 0.000 description 1
- 208000008574 Intracranial Hemorrhages Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 230000002008 hemorrhagic effect Effects 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 238000004088 simulation Methods 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
- A61M5/31505—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
- A61M5/31528—Dosing by means of rotational movements, e.g. screw-thread mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
- A61M5/31505—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
- A61M2005/31506—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit formed as a single piece, e.g. moulded
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M2005/3152—Piston or piston-rod constructions, e.g. connection of piston with piston-rod including gearings to multiply or attenuate the piston displacing force
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The invention discloses a kind of syringes for establishing animal encephalic Hemorrhage Model, belong to field of experiment equipment.Piston pushes away core and is connected by screw-thread fit with core fixed block is pushed away, and piston pushes away core and the upper end for pushing away core fixed block and piston is passed through to connect；Piston is located in syringe outer barrel, and piston is in close contact with syringe outer tube inner wall；Syringe outer barrel includes top thread segment, middle part tube body section and lower thread section, pushes away core fixed block and is connected by screw-thread fit with top thread segment, and needle height adjusts bottom cylinder and is connected by screw-thread fit with lower thread section；Needle height adjusts bottom cylinder lower end lug boss and is connect with pumping needle.The syringe construction reasonable design has reached in animal model experiment is intracranialed hemorrhage in foundation according to experiment demand with different rates slowly to intracranial injection blood, while the purpose of blutpunkte position is accurately positioned.
Description
Technical field
The invention belongs to animal experiment device fields, and in particular to a kind of injection for establishing animal encephalic Hemorrhage Model
Device.
Background technology
Human diseases type is various, and occurrence and development process is usually extremely complex, so needing to carry out medical experiment to visit
The pathogenesis and curative effect of the various diseases of rope are judged, and to reach control disease, extend human longevity, promote medical research into
Step.But various medical experiments are directly applied to human body may bring risk to people, and due to certain diseases be not easy it is common
Or incubation period is long, strongly limits the development of medical research.Zoopery is the important component of medical research field, largely
Medical research shows that the animal model experiment for simulating human diseases can effectively overcome and medical experiment is directly applied to human body
Shortcomings contribute to the generation of more convenient and efficient understanding human diseases, explore the rule of development of disease.
Animal model is the premise for carrying out zoopery, and accurate animal model experiment is capable of the spy of Efficient Characterization human diseases
Point, and animal experiment device usually plays highly important effect during establishing animal model.Due to human body and experiment
Zootomy structure is extremely complex, so for accurate simulation mankind's specified disease, it is desirable that animal experiment device has good
Accuracy.In addition, since experimental animal type is various, while also requiring experimental animal device that there is considerable flexibility.
Cranial vascular disease occupies the third position in the fatal disease of the mankind, it has also become national the first dead big disease in China
Disease, so, cranial vascular disease research is the important directions of Medical research, and it is important in cranial vascular disease to intracranial hemorrhage
Branch and common type.Currently, animal model experiment of intracranialing hemorrhage largely is carried out, wherein self blood injection mode makes
Model of intracranialing hemorrhage is that most commonly seen model production method selects micro syringe or common during modelling
Blood is injected encephalic by fluid injector.But using micro syringe or common liq syringe it is difficult to ensure that slowly by blood
Inject encephalic, true human brain hemorrhagic processes can not be simulated, easily lead to model foundation failure, moreover, using micro syringe or
Common liq syringe is not easy to accurately control the position of blutpunkte, it is difficult to ensure that the consistency and repeatability of Animal Model.
Therefore, in carrying out the animal model experiment intracranialed hemorrhage, need it is a kind of it is easy, effectively establish animal encephalic Hemorrhage Model
Injection device.
Invention content
Go out for establishing animal encephalic in view of the above-mentioned drawbacks of the prior art, the purpose of the present invention is to provide one kind
The injection device of blood model, the injection device is reasonable in design, can ensure slow with different rates according to experiment demand
Slow injection, while blutpunkte position can be accurately controlled.
The present invention is to be achieved through the following technical solutions：
It is disclosed by the invention a kind of for establishing the syringe of animal encephalic Hemorrhage Model, including by top thread segment, in
Portion's tube body section and lower thread section composition syringe outer barrel, in syringe outer barrel be equipped be close to its inner wall and can straight line fortune
Dynamic piston, the upper end of piston are connected with piston and push away core；
It is equipped at the top thread segment of syringe outer barrel and pushes away core fixed block, push away to offer pushing away core for piston on core fixed block
The through-hole passed through, through-hole wall are equipped with internal thread, and piston pushes away core core bar and is equipped with external screw thread, and piston pushes away core and pushes away core fixed block
Screw thread is connected；Scale is equipped on the middle part tube body section outer wall of syringe outer barrel；It is set at the lower thread section of syringe outer barrel
There is needle height to adjust bottom cylinder, needle height adjusts bottom cylinder and is connected by screw-thread fit with lower thread section, and needle height is adjusted
Bottom cylinder lower part is equipped with the lug boss being connected with pumping needle.
Preferably, top thread segment uses internal thread, pushes away the outer spiral shell being equipped on the outside of core fixed block with the screw-internal thread fit
Line.
Preferably, top thread segment uses internal thread, annular groove is offered on pushing away core fixed block, on annular groove inner wall
Equipped with the external screw thread with the screw-internal thread fit.
Preferably, top thread segment uses external screw thread, and annular groove is offered on pushing away core fixed block, is set on annular groove outer wall
There is the internal thread coordinated with the external screw thread.
Preferably, lower thread section uses internal thread, and needle height adjusts bottom drum outer wall and is equipped with matches with the internal thread
The external screw thread of conjunction.
Preferably, lower thread section uses external screw thread, and needle height adjusts bottom cylinder inner wall and is equipped with matches with the external screw thread
The internal thread of conjunction.
Preferably, piston includes piston main body and the piston jacket that is wrapped in outside piston main body, piston jacket and syringe
Outer tube inner wall is close to.
It is further preferred that piston main body is made of organic glass, piston jacket is made of rubber.
Preferably, further include syringe fixed frame, syringe fixed frame is equipped with the card slot for fixing syringe, injection
The mounting hole being connect with experimental facilities is further opened on device fixed frame.
Preferably, piston pushes away core, pushes away core fixed block, syringe outer barrel, needle height adjusting bottom cylinder, lug boss and syringe
Fixed frame is made of organic glass.
Preferably, it is adjusted in needle height and is additionally provided with adjusting knob on the cylinder of bottom.
Compared with prior art, the present invention has technique effect beneficial below：
A kind of syringe for establishing animal encephalic Hemorrhage Model provided by the invention, will use between main components
Helicitic texture is attached, and on the one hand can be simplified each component connection type in syringe, be reduced the complexity of practical operation；
On the other hand, the design of helicitic texture can achieve the purpose that be needed to adjust injection rate and height according to experiment, and the present invention is logical
It crosses three-level threaded adjusting and realizes and injection rate and blutpunkte position are precisely controlled, be in particular in：The first order passes through spiral shell
Line cooperation regulating piston pushes away core and pushes away core fixed block, the fltting speed of regulating piston；The second level pushes away core by screw-thread fit adjusting
Cooperation distance between fixed block and top thread segment is slowly noted to encephalic according to experiment demand with different rates to realize
Penetrate the purpose of blood；The third level since the middle part tube body section of syringe outer barrel is equipped with scale, thus passes through screw-thread fit metering needle
Grease head highness adjusts the cooperation distance between bottom cylinder and lower thread section, you can know the specific distance that lug boss declines, so as to
The pumping needle that enough determinations are connected with lug boss enters the depth of encephalic, so that it is guaranteed that obtaining accurate blutpunkte position and amount
Change the position of piston, moreover it is possible to the accurate volume for reading injection.The syringe construction setting of the present invention is reasonable, easy to operate, makes
With simplicity, for smoothly establishing animal encephalic Hemorrhage Model provides reliable guarantee；Using split-type design, convenient for each component
Cleaning, to ensure that the repeatability and accuracy of model foundation, especially suitable for animal of intracranialing hemorrhage in animal experiment study
The structure of model, easy to operation and accurate modeling.
Further, the top thread segment of syringe outer barrel is connect by screw thread with core fixed block is pushed away, and top thread segment and is pushed away
Screw thread matching setting on core fixed block can guarantee by three kinds of combining forms and push away core fixed block opposing syringe outer barrel
It is threaded in or out, and then core movement is pushed away with piston.
Further, lower thread section adjusts bottom cylinder with needle height by screw thread and connect, and passes through threaded adjusting needle height
The height of bottom cylinder is adjusted, and then adjusts the depth that the pumping needle being connected with lug boss enters encephalic.
Further, piston includes piston main body and the piston jacket that is wrapped in outside piston main body, and piston main body is pushed away with piston
Core connects, and piston jacket is in close contact with syringe outer barrel, not only meets piston and pushes away the connection of core with piston, it can also be ensured that
Piston well moves in syringe outer barrel.
Further, syringe fixed frame is fixed on experimental facilities by mounting hole, is fixed syringe by card slot
On syringe fixed frame, it is ensured that stability of syringe during injecting blood.
Further, it can also be adjusted in needle height and adjusting knob is set on the drum outer wall of bottom, it can by rotation of adjustment knob
Easily turn needle height adjusting knob, depth of the adjusting syringe needle in encephalic.
Description of the drawings
Fig. 1 is the structural schematic diagram of the syringe of the present invention；
Fig. 2 is to push away core fixed block lateral wall to use externally threaded structural schematic diagram；
Fig. 3 is to push away core fixed block to use the externally threaded structural schematic diagram of annular groove；
Fig. 4 is the structural schematic diagram for pushing away core fixed block and using annular groove internal thread；
Fig. 5 is piston structure schematic diagram；
Fig. 6 is the first structural schematic diagram of syringe outer barrel；
Fig. 7 is second of structural schematic diagram of syringe outer barrel；
Fig. 8 is the third structural schematic diagram of syringe outer barrel；
Fig. 9 is the 4th kind of structural schematic diagram of syringe outer barrel；
Figure 10 is the structural schematic diagram that needle height adjusts that outer barrel uses internal thread；
Figure 11 is that needle height adjusts outer barrel using externally threaded structural schematic diagram；
Figure 12 is the front view of syringe fixed frame；
Figure 13 is the attached view of syringe fixed frame.
In figure：1 pushes away core for piston；2 be to push away core fixed block；21 be through-hole；22 be annular groove；3 be piston；31 be piston master
Body；32 be piston jacket；4 be syringe outer barrel；41 be top thread segment；41a is upper internal threaded；41b is upper external thread；
42 be middle part tube body section；43 be lower thread section；43a is lower internal thread；43b is lower external thread；5 are adjusted for needle height
Bottom cylinder；51a is bottom cylinder internal thread；51b is bottom cylinder external screw thread；52 connect card slot for syringe needle；53 be adjusting knob；6 be lug boss；
7 be syringe fixed frame；71 be mounting hole；72 be card slot；.
Specific implementation mode
With reference to specific embodiment, the present invention is described in further detail, it is described be explanation of the invention and
It is not to limit.
As shown in Figure 1, the syringe for establishing animal encephalic Hemorrhage Model of disclosure of the invention, including piston push away core
1, core fixed block 2, piston 3, syringe outer barrel 4, needle height are pushed away and adjusts bottom cylinder 5 and lug boss 6.Piston push away core 1 pass through push away core
Fixed block 2 is connect with the upper end of piston 3, and piston pushes away core 1 and is connected with core fixed block 2 is pushed away by screw thread；Pushing away core fixed block 2
Center offers a through-hole 21, and the inner wall of through-hole 21 is equipped with internal thread, piston push away core 1 outer wall be equipped with on through-hole 21 in
The adaptable external screw thread of screw thread allows piston to push away core 1 and be threaded in or out and pushes away core fixed block 2 by screw-thread fit.
Syringe outer barrel 4 includes 43 three parts of top thread segment 41, middle part tube body section 42 and lower thread section, top screw thread
Section 41 is connected with core fixed block 2 is pushed away, and middle part tube body section 42 is in close contact with piston 3, lower thread section 43 and needle height tune
Section bottom cylinder 5 is connected.
It pushes away core fixed block 2 by screw thread to be connected with the top thread segment 41 of syringe outer barrel 4, including following three kinds of cooperations
Form：
The first：Top thread segment 41 uses upper internal threaded 41a, push away the outside of core fixed block 2 be equipped with it is adaptable therewith
External screw thread；
Second：Top thread segment 41 uses upper internal threaded 41a, and an annular groove 22 is offered on pushing away core fixed block 2,
External screw thread adaptable therewith is equipped on 22 madial wall of annular groove；
The third：Top thread segment 41 uses upper external thread 41b, and an annular groove 22 is offered on pushing away core fixed block 2,
Internal thread adaptable therewith is equipped on 22 lateral wall of annular groove.
Above-mentioned three kinds of fit forms can meet the relative rotary motion for pushing away core fixed block 2 and syringe outer barrel 4, preferably
Using the first fit form, because its is simple in structure.
Piston 3 is located in syringe outer barrel 4, and piston 3 is close to 4 inner wall of syringe outer barrel, when piston 3 is pushed by external force
It can be moved in a straight line along 4 inner wall of syringe outer barrel, when regulating piston pushes away the height of core 1, since piston pushes away the lower end of core 1
It is connected with the upper end of piston 3, to the mobile height of regulating piston 3.
Needle height adjusts bottom cylinder 5 and is connected with the lower thread section 43 of syringe outer barrel 4 by screw thread, and connection includes
Following two fit forms：
The first：When lower part thread segment 43 is using lower internal thread 43a, needle height adjusts bottom 5 outer walls of cylinder and is equipped with
Adaptable bottom cylinder external screw thread 51b therewith；
Second：When lower part thread segment 43 is using lower external thread 43b, needle height adjusts bottom 5 inner walls of cylinder and is equipped with
Adaptable bottom cylinder internal thread 51a therewith.
Preferably, when needle height adjusts bottom cylinder 5 using internal thread, bottom 5 outer walls of cylinder can also be adjusted in needle height
Upper setting adjusting knob 53 can easily turn needle height adjusting bottom cylinder 5 by rotating adjusting knob 53, needle height is made to adjust
Bottom 5 opposing syringe outer barrels 4 of cylinder rotate movement and are easier, and then conveniently adjust syringe needle 6 in encephalic by screw thread
Depth.
Lug boss 6 is equipped with syringe needle and connects card slot 52, the pumping needle for connecting various models.
As illustrated by figs. 12-13, stability and convenience when considering to use, the present invention are also provided with syringe fixed frame 7,
It is equipped with card slot 72 on syringe fixed frame 7, syringe of the present invention is fixed in card slot 72, syringe fixed frame 7
On be additionally provided with mounting hole 71, it is real that syringe fixed frame 7 is fixed on animal experimental table or stereotaxic instrument etc. by mounting hole 71
It tests in equipment, it is ensured that stability of syringe during injecting blood.
Preferably, piston pushes away core 1, pushes away core fixed block 2, syringe outer barrel 4, needle height adjusting bottom cylinder 5,6 and of lug boss
Syringe fixed frame 7 is commonly called as organic glass by there is polymethyl methacrylate to be made；As shown in figure 5, piston 3 includes piston
32 two parts of main body 21 and piston jacket, piston main body 31 are made of organic glass, and piston jacket 32 is made of rubber.
The syringe for establishing animal encephalic Hemorrhage Model of the present invention, when in use：
First, syringe is fixed in the card slot 72 of syringe fixed frame 7, secondly, syringe fixed frame 7 is passed through solid
Determine hole 71 to be fixed on experimental facilities, then, the self blood of animal is injected into the middle part tube body section 42 of syringe outer barrel 4, is waited for
After animal sphenotresia, the pumping needle being connected with lug boss 6 is entered into encephalic along skull hole, and pass through syringe needle height
The depth that the pumping needle connected on 5 adjusting lug boss 6 of degree adjusting bottom cylinder enters encephalic finally pushes away core 1 by regulating piston,
According to certain rate slowly to intracranial injection blood.
The adjustment that is threaded in or out by pushing away core fixed block 2 pushes away the depth that core fixed block 2 enters syringe outer barrel 4, quite
Core 1 is pushed away into 4 depth of syringe outer barrel in having adjusted piston, and core 1 can be pushed away with regulating piston and enters the depth for pushing away core fixed block 2
Degree, the depth for pushing away core 1 into syringe to piston are further adjusted, and are pushed away core 1 by regulating piston and are pushed away core fixed block
2, realize the different fltting speeds of piston 3.
Each component after having used, can be dismantled, be cleaned, convenient for cleaning each component by each section independent design
Totally, to ensure that the repeatability and accuracy of model foundation.
In conclusion the syringe provided by the present invention for establishing animal encephalic Hemorrhage Model, realizes and is establishing cranium
It can be simultaneously accurately positioned with different rates slowly to intracranial injection blood according to experiment demand in internal haemorrhage animal model experiment
Blutpunkte position can accurately control the making for animal model of intracranialing hemorrhage, especially suitable in animal experiment study
It intracranials hemorrhage the structure of animal model, easy to operation and accurate modeling.
Claims (10)
1. a kind of for establishing the syringe of animal encephalic Hemorrhage Model, which is characterized in that including by top thread segment (41), in
The syringe outer barrel (4) of portion's tube body section (42) and lower thread section (43) composition, is equipped with and its inner wall in syringe outer barrel (4)
The piston (3) be close to and can moved along a straight line, the upper end of piston (3) are connected with piston and push away core (1)；
It is equipped at the top thread segment (41) of syringe outer barrel (4) and pushes away core fixed block (2), pushed away and offered on core fixed block (2)
The through-hole (21) that core (1) passes through is pushed away for piston, through-hole (21) inner wall is equipped with internal thread, and piston pushes away core (1) core bar equipped with outer
Screw thread, piston push away core (1) and are connected with core fixed block (2) screw thread is pushed away；On middle part tube body section (42) outer wall of syringe outer barrel (4)
Equipped with scale；It is equipped with needle height at the lower thread section (43) of syringe outer barrel (4) and adjusts bottom cylinder (5), needle height tune
Section bottom cylinder (5) is connected with lower thread section (43) by screw-thread fit, and needle height adjusting bottom cylinder (5) lower part is equipped with and injection
The connected lug boss (6) of needle.
2. the syringe as described in claim 1 for establishing animal encephalic Hemorrhage Model, which is characterized in that top thread segment
(41) internal thread is used, the external screw thread being equipped on the outside of core fixed block (2) with the screw-internal thread fit is pushed away.
3. the syringe as described in claim 1 for establishing animal encephalic Hemorrhage Model, which is characterized in that top thread segment
(41) use internal thread, annular groove (22) is offered on pushing away core fixed block (2), on annular groove (22) inner wall be equipped with it is described
The external screw thread of screw-internal thread fit.
4. the syringe as described in claim 1 for establishing animal encephalic Hemorrhage Model, which is characterized in that top thread segment
(41) use external screw thread, offer annular groove (22) on pushing away core fixed block (2), annular groove (22) outer wall be equipped with it is described outer
The internal thread of screw-thread fit.
5. the syringe as described in claim 1 for establishing animal encephalic Hemorrhage Model, which is characterized in that lower thread section
(43) internal thread, needle height is used to adjust bottom cylinder (5) outer wall equipped with the external screw thread with the screw-internal thread fit.
6. the syringe as described in claim 1 for establishing animal encephalic Hemorrhage Model, which is characterized in that lower thread section
(43) external screw thread, needle height is used to adjust bottom cylinder (5) inner wall and be equipped with the internal thread coordinated with the external screw thread.
7. the syringe for establishing animal encephalic Hemorrhage Model as described in any one of claim 1~6, feature exist
Include piston main body (31) in, piston (3) and be wrapped in the piston jacket (32) of piston main body (31) outside, piston jacket (32) with
Syringe outer barrel (4) inner wall is close to.
8. the syringe as claimed in claim 7 for establishing animal encephalic Hemorrhage Model, which is characterized in that piston main body
(31) it is made of organic glass, piston jacket (32) is made of rubber.
9. the syringe for establishing animal encephalic Hemorrhage Model as described in any one of claim 1~6, feature exist
In further including syringe fixed frame (7), syringe fixed frame (7) is equipped with the card slot (72) for fixing syringe, syringe
The mounting hole (71) being connect with experimental facilities is further opened on fixed frame (7).
10. the syringe as claimed in claim 9 for establishing animal encephalic Hemorrhage Model, which is characterized in that piston pushes away core
(1), core fixed block (2), syringe outer barrel (4), needle height are pushed away and adjusts bottom cylinder (5), lug boss (6) and syringe fixed frame
(7) it is made of organic glass.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810687831.9A CN108720962A (en) | 2018-06-28 | 2018-06-28 | A kind of syringe for establishing animal encephalic Hemorrhage Model |
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| CN201810687831.9A CN108720962A (en) | 2018-06-28 | 2018-06-28 | A kind of syringe for establishing animal encephalic Hemorrhage Model |
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| CN201022887Y (en) * | 2007-03-17 | 2008-02-20 | 马群山 | Screw propelling syringe |
| CN203235097U (en) * | 2013-04-01 | 2013-10-16 | 中国人民解放军总医院第一附属医院 | Injector |
| CN203663176U (en) * | 2014-01-08 | 2014-06-25 | 朱珂 | Anaesthetic needle |
| CN205108585U (en) * | 2015-10-21 | 2016-03-30 | 成都青山利康药业有限公司 | Area sterilization protection device's preliminary filling formula syringe |
| CN205163824U (en) * | 2015-11-24 | 2016-04-20 | 中国人民解放军第四军医大学 | Infusion device is assisted in angiocardiography |
| CN205698739U (en) * | 2016-05-13 | 2016-11-23 | 刘俊英 | A kind of cardioangiography syringe |
| CN210811732U (en) * | 2018-06-28 | 2020-06-23 | 中国人民解放军第四军医大学 | Injector for establishing animal intracranial hemorrhage model |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201022887Y (en) * | 2007-03-17 | 2008-02-20 | 马群山 | Screw propelling syringe |
| CN203235097U (en) * | 2013-04-01 | 2013-10-16 | 中国人民解放军总医院第一附属医院 | Injector |
| CN203663176U (en) * | 2014-01-08 | 2014-06-25 | 朱珂 | Anaesthetic needle |
| CN205108585U (en) * | 2015-10-21 | 2016-03-30 | 成都青山利康药业有限公司 | Area sterilization protection device's preliminary filling formula syringe |
| CN205163824U (en) * | 2015-11-24 | 2016-04-20 | 中国人民解放军第四军医大学 | Infusion device is assisted in angiocardiography |
| CN205698739U (en) * | 2016-05-13 | 2016-11-23 | 刘俊英 | A kind of cardioangiography syringe |
| CN210811732U (en) * | 2018-06-28 | 2020-06-23 | 中国人民解放军第四军医大学 | Injector for establishing animal intracranial hemorrhage model |
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