CN108717118B - Tray assembly for fluorescence immunoassay analyzer and reagent card used in cooperation with same - Google Patents

Tray assembly for fluorescence immunoassay analyzer and reagent card used in cooperation with same Download PDF

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Publication number
CN108717118B
CN108717118B CN201810524607.8A CN201810524607A CN108717118B CN 108717118 B CN108717118 B CN 108717118B CN 201810524607 A CN201810524607 A CN 201810524607A CN 108717118 B CN108717118 B CN 108717118B
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tray
reagent card
card
groove
turntable
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CN108717118A (en
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张娟丽
蔡永朋
李伟甲
许泼实
高勇
孙月鹏
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Zhongxiu Technology Co ltd
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Zhongxiu Technology Co ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals

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  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
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  • Urology & Nephrology (AREA)
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  • General Physics & Mathematics (AREA)
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  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

The invention discloses a tray component for a fluorescence immunoassay analyzer and a reagent card matched with the tray component for use, wherein the tray component comprises a tray and a turntable positioned on the tray, the tray is provided with a limiting ring coaxially arranged with the tray, and the limiting ring is provided with a notch for the reagent card to enter and exit; the tray and the turntable are coaxially arranged, and the turntable is connected with a stepping motor capable of driving the turntable to rotate; more than two clamping grooves for clamping reagent cards are radially arranged on the rotary table, the width of each clamping groove gradually increases from the groove bottom to the notch, and a first electromagnet is arranged at the groove bottom of each clamping groove; the limiting ring inner wall and the clamping groove inner wall can be provided with grooves at the positions contacted with the reagent card, and the width of the grooves is matched with the thickness of the edge of the reagent card. This application does not need specific card pushing mechanism just can take out the reagent card that the test finishes, and simple structure improves assembly efficiency and reduce cost.

Description

Tray assembly for fluorescence immunoassay analyzer and reagent card used in cooperation with same
Technical Field
The invention relates to the technical field of fluorescence immunoassay, in particular to a tray component for a fluorescence immunoassay instrument and a reagent card matched with the tray component.
Background
The fluorescence immunoassay technology has the advantages of strong specificity, high sensitivity, good practicability and the like, so the fluorescence immunoassay technology is used for measuring bioactive compounds with low content, such as enzyme, acceptor, antibody, steroid, thyroid hormone, phthalein hormone, medicine, microorganism and the like, and has wide application range and wide application range.
The existing fluorescence immunoassay analyzer is mostly required to be provided with a specific card pushing mechanism when the card is withdrawn so as to take out the tested reagent card, the structure is complex, the assembly efficiency is reduced, and the cost is increased, so that a novel tray component without an additional card pushing mechanism is particularly necessary.
Disclosure of Invention
The invention aims to provide a tray component for a fluorescence immunoassay analyzer and a reagent card matched with the tray component, and solves the problems that the existing fluorescence immunoassay analyzer needs to be provided with a specific card pushing mechanism to take out a tested reagent card when the card is withdrawn, the structure is complex, the assembly efficiency is reduced, and the cost is increased.
In order to solve the technical problems, the invention adopts the following technical scheme:
a tray assembly for a fluorescence immunoassay analyzer comprises a tray and a turntable positioned on the tray,
the tray is provided with a limiting ring which is coaxial with the tray, and the limiting ring is provided with a notch for the reagent card to enter and exit;
the tray and the turntable are coaxially arranged, and the turntable is connected with a stepping motor capable of driving the turntable to rotate;
more than two clamping grooves for clamping reagent cards are radially arranged on the rotary table, the width of each clamping groove gradually increases from the groove bottom to the notch, and a first electromagnet is arranged at the groove bottom of each clamping groove;
the limiting ring inner wall and the clamping groove inner wall can be provided with grooves at the positions contacted with the reagent card, and the width of the grooves is matched with the thickness of the edge of the reagent card.
When the fluorescence immunoassay appearance tray subassembly in this application used, inserted the draw-in groove from the breach with the reagent card, then opened the power of first electro-magnet, magnetism on the reagent card will be fast with first electro-magnet inter attraction, play the effect of location, then step motor drives the carousel and rotates, goes to next draw-in groove and breach and aims at, inserts the reagent card once more to this analogizes. The reagent card rotates along with the rotary table, when the reagent card rotates to a designated position, the code is swept to identify and check the item information on the reagent card, the item information is checked to be correct, the test and the analysis are carried out, then the reagent card continuously rotates and rotates to the notch again, the power supply of the first electromagnet is turned off, and as the width of the clamping groove from the groove bottom to the notch is gradually increased, the rotary table can provide clamping force for the reagent card, the reagent card can be popped out outwards along the radial direction after the attractive force of the first electromagnet and the magnetic block and the supporting force of the limiting ring on the reagent card do not exist, and the card withdrawing is realized.
First electro-magnet in this application can make every draw-in groove be provided with a first electro-magnet single control alone, also can control together because when the reagent card does not aim at the breach, the support reagent card of limit ring also can not take place the displacement.
In addition, the inner wall of the limiting ring and the inner wall of the clamping groove are provided with grooves in positions capable of contacting with the reagent card, and the reagent card can slide along the grooves to prevent the reagent card from inclining or separating from the clamping groove.
Preferably, the outer side of the notch is provided with a card withdrawing sliding groove along the radial direction of the rotating disc.
The outside of the gap is provided with a card withdrawing chute for collecting reagent cards.
Preferably, the top of the groove wall of the card withdrawing chute is bent inwards to form a baffle plate, so that the reagent card is prevented from popping upwards and deviating from a preset track, and the damage rate is reduced.
Preferably, the buffer layer is arranged on the inner side of the groove wall of the card withdrawing chute, so that impact between the reagent card and the groove wall in the sliding process is reduced, and the damage rate is reduced.
Preferably, a U-shaped clamp which is made of magnetic materials and used for clamping the reagent card is arranged below the rotary disc, and the U-shaped clamp is connected with the tray through an elastic piece;
the width of the U-shaped clamp is matched with that of the reagent card, and the rotary disc is provided with a second electromagnet capable of attracting the U-shaped clamp mutually.
When code scanning or testing is carried out, the requirement on the accuracy of the position of the reagent card is higher, so that the U-shaped clamp is arranged to play a role in positioning. In addition, the up-and-down movement frequency of the U-shaped clamp is matched with the rotation frequency of the rotary table, after the test is finished, the second magnet is connected with a power supply, the U-shaped clamp moves downwards, then the rotary table is controlled to rotate, when another reagent card rotates to the position above the U-shaped clamp, the second magnet is disconnected with the power supply, the U-shaped clamp moves upwards, and the reagent card is clamped. The operation can be directly controlled by the single chip microcomputer or provided with a sensor, and the U-shaped clamp is instructed to move upwards after the reagent card is sensed to reach a designated position.
Preferably, the elastic part comprises a telescopic rod and a spring sleeved on the telescopic rod, one end of the spring is fixed at the bottom end of the telescopic rod or on the tray, and the other end of the spring is fixed at the top end of the telescopic rod or on the U-shaped clamp.
The utility model provides a can with fluorescence immunoassay appearance is with tray subassembly cooperation reagent card that uses, the shape of reagent card and the shape looks adaptation of draw-in groove, and be provided with the magnetic block that can attract each other with first electro-magnet on the reagent card with the first electro-magnet position correspondence.
Preferably, the edge of each groove and the edge of each reagent card are provided with polytetrafluoroethylene coatings, so that friction between the grooves and the reagent cards in the sliding process is reduced, and abrasion is reduced.
Compared with the prior art, the invention has the beneficial effects of at least one of the following:
the reagent card after the test can be taken out without a specific card pushing mechanism, the structure is simple, the assembly efficiency is improved, and the cost is reduced.
This application can set up the position of U-shaped clamp and breach as required for when a reagent card of U-shaped clamp centre gripping, another reagent screens that the test finishes just is located breach department, so that move back the card and the test is gone on in step, raises the efficiency.
Drawings
FIG. 1 is a schematic structural diagram of a tray assembly for a fluorescence immunoassay analyzer of the present invention used in combination with a reagent card.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Example 1:
the present embodiment provides a tray assembly for a fluorescence immunoassay analyzer, as shown in fig. 1, comprising a tray 1 and a turntable 2 positioned on the tray 1,
the tray 1 is provided with a limiting ring 4 which is coaxial with the tray 1, and the limiting ring 4 is provided with a notch 41 for the reagent card 3 to enter and exit;
the tray 1 and the turntable 2 are coaxially arranged, and the turntable 2 is connected with a stepping motor capable of driving the turntable 2 to rotate;
more than two clamping grooves 21 for clamping the reagent cards 3 are radially arranged on the rotary table 2, the width of each clamping groove 21 gradually increases from the groove bottom to the groove opening, and a first electromagnet is arranged at the groove bottom of each clamping groove 21;
the inner wall of the limiting ring 4 and the inner wall of the clamping groove 21 are provided with grooves in the places where the inner wall can contact with the reagent card 3, and the width of each groove is matched with the thickness of the edge of the reagent card 3.
When the fluorescence immunoassay appearance tray subassembly in this application used, insert draw-in groove 21 with reagent card 3 from breach 41 department, then open the power of first electro-magnet, magnetism on the reagent card 3 will be fast with first electro-magnet inter attraction, play the effect of location, then step motor drives carousel 2 and rotates, and it aims at with breach 41 to turn to next draw-in groove 21, inserts reagent card 3 once more to this analogizes. The reagent card 3 rotates along with the rotary disc 2, when the reagent card 3 rotates to a designated position, the code is scanned to identify and check the item information on the reagent card 3, the item information is checked, tested and analyzed, then the reagent card continues to rotate, the reagent card 3 rotates to the notch 41 again, the power supply of the first electromagnet is turned off, and as the width of the clamping groove 21 from the groove bottom to the notch is gradually increased, the rotary disc 2 can provide clamping force for the reagent card 3, the reagent card 3 can be ejected outwards along the radial direction after the attractive force of the first electromagnet and the magnetic block and the supporting force of the limiting ring 4 on the reagent card 3 do not exist, and the card withdrawing is realized.
The first electromagnet in the present application can make each card slot 21 individually provided with a first electromagnet to control individually, and also control together, because when the reagent card 3 is not aligned with the notch 41, the reagent card 3 supported by the limiting ring 4 will not be displaced.
In addition, the inner wall of the limiting ring 4 and the inner wall of the clamping groove 21 are provided with grooves at the positions where the inner wall of the limiting ring can contact with the reagent card 3, and the reagent card 3 can slide along the grooves to prevent the reagent card 3 from inclining or separating from the clamping groove 21.
Example 2:
this embodiment further defines, on the basis of embodiment 1: and a card withdrawing sliding groove 5 is arranged on the outer side of the notch 41 along the radial direction of the rotary disc 2.
The card withdrawing chute 5 is arranged outside the notch 41 and is used for collecting the reagent card 3.
Example 3:
this embodiment further defines, on the basis of embodiment 2: the top of the slot wall of the card withdrawing chute 5 is bent inwards to form a baffle plate, so that the reagent card 3 is prevented from popping upwards and deviating from a preset track, and the damage rate is reduced.
Example 4:
this embodiment further defines, on the basis of embodiment 2: the buffer layer is arranged on the inner side of the groove wall of the card withdrawing sliding groove 5, so that the impact between the reagent card 3 and the groove wall in the sliding process is reduced, and the damage rate is reduced.
Example 5:
this embodiment further defines, on the basis of embodiment 1: a U-shaped clamp 6 which is made of magnetic materials and used for clamping a reagent card is arranged below the rotary table 2, and the U-shaped clamp is connected with the tray 1 through an elastic piece;
the width of the U-shaped clamp is matched with that of the reagent card, and the rotary disc is provided with a second electromagnet capable of attracting the U-shaped clamp mutually.
When code scanning or testing is carried out, the requirement on the accuracy of the position of the reagent card is higher, so that the U-shaped clamp is arranged to play a role in positioning. In addition, the up-and-down movement frequency of the U-shaped clamp is matched with the rotation frequency of the rotary table, after the test is finished, the second magnet is connected with a power supply, the U-shaped clamp moves downwards, then the rotary table is controlled to rotate, when another reagent card rotates to the position above the U-shaped clamp, the second magnet is disconnected with the power supply, the U-shaped clamp moves upwards, and the reagent card is clamped. The operation can be directly controlled by the single chip microcomputer or provided with a sensor, and the U-shaped clamp is instructed to move upwards after the reagent card is sensed to reach a designated position.
Example 6:
this example further defines, on the basis of example 5: the elastic piece comprises a telescopic rod and a spring sleeved on the telescopic rod, one end of the spring is fixed at the bottom end of the telescopic rod or on the tray, and the other end of the spring is fixed at the top end of the telescopic rod or on the U-shaped clamp.
Example 7:
the embodiment provides a reagent card that can cooperate with tray subassembly for fluorescence immunoassay appearance and use, the shape of reagent card 3 and the shape looks adaptation of draw-in groove 21, and be provided with the magnetic block that can attract each other with first electro-magnet on the reagent card 3 with the first electro-magnet position correspondence.
Example 8:
this example further defines, on the basis of example 7: the edge of the groove and the edge of the reagent card 3 are both provided with polytetrafluoroethylene coatings, so that the friction between the groove and the reagent card 3 in the sliding process is reduced, and the abrasion is reduced.
Although the invention has been described herein with reference to a number of illustrative embodiments thereof, it should be understood that numerous other modifications and embodiments can be devised by those skilled in the art that will fall within the spirit and scope of the principles of this disclosure. More specifically, various variations and modifications are possible in the component parts and/or arrangements of the subject combination arrangement within the scope of the disclosure, the drawings and the appended claims. In addition to variations and modifications in the component parts and/or arrangements, other uses will also be apparent to those skilled in the art.

Claims (4)

1. A tray component for a fluorescence immunoassay analyzer comprises a tray (1) and a turntable (2) positioned on the tray (1), and is characterized in that,
a limiting ring (4) which is coaxial with the tray (1) is arranged on the tray (1), and a notch (41) for the reagent card (3) to enter and exit is arranged on the limiting ring (4);
the tray (1) and the turntable (2) are coaxially arranged, and the turntable (2) is connected with a stepping motor capable of driving the turntable (2) to rotate;
more than two clamping grooves (21) used for clamping the reagent card (3) are radially arranged on the rotary table (2), the width of each clamping groove (21) from the groove bottom to the notch is gradually increased, and a first electromagnet is arranged at the groove bottom of each clamping groove (21);
grooves are formed in the inner wall of the limiting ring (4) and the inner wall of the clamping groove (21) at positions where the inner wall can be in contact with the reagent card (3), and the width of each groove is matched with the thickness of the edge of the reagent card (3);
a U-shaped clamp (6) which is made of magnetic materials and used for clamping the reagent card (3) is arranged below the rotary disc (2), and the U-shaped clamp is connected with the tray through an elastic piece;
the width of the U-shaped clamp is matched with that of the reagent card (3), and a second electromagnet capable of attracting the U-shaped clamp mutually is arranged on the rotary disc;
the elastic piece comprises a telescopic rod and a spring sleeved on the telescopic rod, one end of the spring is fixed at the bottom end of the telescopic rod or on the tray, and the other end of the spring is fixed at the top end of the telescopic rod or on the U-shaped clamp.
2. The tray assembly for a fluoroimmunoassay analyzer of claim 1, wherein the outside of the notch (41) is provided with a card-withdrawing chute (5) in the radial direction of the turntable (2).
3. The tray assembly for a fluorescence immunoassay analyzer according to claim 2, wherein the top of the groove wall of the card ejection chute (5) is bent inward to form a baffle.
4. The tray assembly for a fluorescence immunoassay analyzer according to claim 2, wherein a buffer layer is provided on the inner side of the groove wall of the card ejection chute (5).
CN201810524607.8A 2018-05-28 2018-05-28 Tray assembly for fluorescence immunoassay analyzer and reagent card used in cooperation with same Active CN108717118B (en)

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CN112924677B (en) * 2021-01-22 2024-01-30 重庆市中医院 Equipment for early screening of tumors
CN114252598A (en) * 2021-12-16 2022-03-29 广州万孚生物技术股份有限公司 Card insertion device, fluorescence immunoassay instrument and control method of card insertion device

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CN206725575U (en) * 2017-05-19 2017-12-08 广州源起健康科技有限公司 A kind of incubation disk device of chemical illumination immunity analysis instrument
CN207007715U (en) * 2017-07-07 2018-02-13 广州蓝勃生物科技有限公司 A kind of analyzer reagent card card feed mechanism and detection rotating disk
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