CN108712913B - 内体g蛋白-偶联的受体的三部分调节剂 - Google Patents

内体g蛋白-偶联的受体的三部分调节剂 Download PDF

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CN108712913B
CN108712913B CN201680074910.1A CN201680074910A CN108712913B CN 108712913 B CN108712913 B CN 108712913B CN 201680074910 A CN201680074910 A CN 201680074910A CN 108712913 B CN108712913 B CN 108712913B
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endosomal
formula
optionally
compound
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CN108712913A (zh
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N.W.邦尼特
C.J.H.波特
D.科尔
G.希克斯
J.希赖
G.赫斯特
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Takeda Pharmaceutical Co Ltd
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    • A—HUMAN NECESSITIES
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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CN201680074910.1A 2015-12-22 2016-12-21 内体g蛋白-偶联的受体的三部分调节剂 Active CN108712913B (zh)

Priority Applications (1)

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CN202210637197.4A CN115531553A (zh) 2015-12-22 2016-12-21 内体g蛋白-偶联的受体的三部分调节剂

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AU2015905333A AU2015905333A0 (en) 2015-12-22 Modulators of Endosomal G Protein-Coupled Receptors
AU2015905333 2015-12-22
US201662291161P 2016-02-04 2016-02-04
US62/291,161 2016-02-04
PCT/US2016/068075 WO2017112792A1 (en) 2015-12-22 2016-12-21 Tripartite modulators of endosomal g protein-coupled receptors

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CN108712913B true CN108712913B (zh) 2022-06-24

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CN202210637197.4A Pending CN115531553A (zh) 2015-12-22 2016-12-21 内体g蛋白-偶联的受体的三部分调节剂

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US (3) US11324832B2 (https=)
EP (1) EP3393519A1 (https=)
JP (3) JP7074673B2 (https=)
CN (2) CN108712913B (https=)
AU (3) AU2016377658B2 (https=)
CA (1) CA3009325A1 (https=)
EA (1) EA201891472A1 (https=)
WO (1) WO2017112792A1 (https=)

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CA2978736C (en) 2015-03-04 2023-11-07 Vanda Pharmaceuticals Inc. Dosing regimen of tradipitant
WO2017112792A1 (en) * 2015-12-22 2017-06-29 Takeda Pharmaceutical Company Limited Tripartite modulators of endosomal g protein-coupled receptors
CN109152777A (zh) * 2016-05-20 2019-01-04 武田药品工业株式会社 疼痛的治疗
KR20250140655A (ko) * 2017-11-17 2025-09-25 반다 파마슈티칼즈, 인코퍼레이티드. 트라디피탄트를 이용한 위장 질환의 치료 방법
IT202200018780A1 (it) * 2022-09-14 2024-03-14 Alberto Chiarugi Modulatori degli effetti della chemioterapia
IT202200018768A1 (it) * 2022-09-14 2024-03-14 Alberto Chiarugi Trattamento della nausea e vomito da chemioterapia

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WO2005097199A1 (en) * 2004-04-08 2005-10-20 Jadolabs Gmbh Tripartite conjugates containing a structure interacting with cell membrane rafts and their use
WO2006004195A1 (en) * 2004-07-02 2006-01-12 Tanabe Seiyaku Co., Ltd. Piperidine compound and process for preparing the same

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US11324832B2 (en) 2022-05-10
JP2019503356A (ja) 2019-02-07
AU2016377658A1 (en) 2018-06-21
US20190000981A1 (en) 2019-01-03
US20230119819A1 (en) 2023-04-20
AU2025201136A1 (en) 2025-03-06
CA3009325A1 (en) 2017-06-29
JP2024073581A (ja) 2024-05-29
AU2022291659A1 (en) 2023-02-02
EP3393519A1 (en) 2018-10-31
BR112018012425A2 (pt) 2018-12-18
EA201891472A1 (ru) 2018-12-28
CN115531553A (zh) 2022-12-30
JP7458681B2 (ja) 2024-04-01
JP7074673B2 (ja) 2022-05-24
WO2017112792A1 (en) 2017-06-29
US20250235544A1 (en) 2025-07-24
AU2016377658B2 (en) 2022-09-29
CN108712913A (zh) 2018-10-26
JP2022113164A (ja) 2022-08-03

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