CN108704104A - A kind of Chinese medicine composition and preparation method thereof for treating cervical spondylosis, protrusion of lumber intervertebral disc, osteoproliferation - Google Patents
A kind of Chinese medicine composition and preparation method thereof for treating cervical spondylosis, protrusion of lumber intervertebral disc, osteoproliferation Download PDFInfo
- Publication number
- CN108704104A CN108704104A CN201810858299.2A CN201810858299A CN108704104A CN 108704104 A CN108704104 A CN 108704104A CN 201810858299 A CN201810858299 A CN 201810858299A CN 108704104 A CN108704104 A CN 108704104A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- root
- chinese medicine
- bark
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 31
- 239000000203 mixture Substances 0.000 title claims abstract description 26
- 238000002360 preparation method Methods 0.000 title claims abstract description 24
- 206010041591 Spinal osteoarthritis Diseases 0.000 title claims abstract description 22
- 208000036319 cervical spondylosis Diseases 0.000 title claims abstract description 22
- 208000005801 spondylosis Diseases 0.000 title claims abstract description 22
- 238000011282 treatment Methods 0.000 claims abstract description 32
- 239000002994 raw material Substances 0.000 claims abstract description 27
- 241000241125 Gryllotalpa gryllotalpa Species 0.000 claims abstract description 22
- 244000131316 Panax pseudoginseng Species 0.000 claims abstract description 20
- 241000427159 Achyranthes Species 0.000 claims abstract description 19
- 244000020518 Carthamus tinctorius Species 0.000 claims abstract description 19
- 235000003255 Carthamus tinctorius Nutrition 0.000 claims abstract description 19
- 244000037364 Cinnamomum aromaticum Species 0.000 claims abstract description 19
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims abstract description 19
- 240000004307 Citrus medica Species 0.000 claims abstract description 19
- 240000007311 Commiphora myrrha Species 0.000 claims abstract description 19
- 235000006965 Commiphora myrrha Nutrition 0.000 claims abstract description 19
- 241000218176 Corydalis Species 0.000 claims abstract description 19
- 241001148782 Davallia Species 0.000 claims abstract description 19
- 240000003537 Ficus benghalensis Species 0.000 claims abstract description 19
- 244000153234 Hibiscus abelmoschus Species 0.000 claims abstract description 19
- 244000241872 Lycium chinense Species 0.000 claims abstract description 19
- 235000015468 Lycium chinense Nutrition 0.000 claims abstract description 19
- 241000361919 Metaphire sieboldi Species 0.000 claims abstract description 19
- 235000007265 Myrrhis odorata Nutrition 0.000 claims abstract description 19
- 235000006040 Prunus persica var persica Nutrition 0.000 claims abstract description 19
- 240000004824 Trimezia steyermarkii Species 0.000 claims abstract description 19
- 239000009136 dragon's blood Substances 0.000 claims abstract description 19
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 19
- 244000144730 Amygdalus persica Species 0.000 claims abstract description 18
- 244000189799 Asimina triloba Species 0.000 claims abstract description 18
- 235000006264 Asimina triloba Nutrition 0.000 claims abstract description 18
- 235000003717 Boswellia sacra Nutrition 0.000 claims abstract description 18
- 240000007551 Boswellia serrata Species 0.000 claims abstract description 18
- 235000012035 Boswellia serrata Nutrition 0.000 claims abstract description 18
- 235000009467 Carica papaya Nutrition 0.000 claims abstract description 18
- 241000756943 Codonopsis Species 0.000 claims abstract description 18
- 239000004863 Frankincense Substances 0.000 claims abstract description 18
- 235000003181 Panax pseudoginseng Nutrition 0.000 claims abstract description 18
- 241000157352 Uncaria Species 0.000 claims abstract description 18
- 241000123589 Dipsacus Species 0.000 claims abstract description 17
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims abstract description 17
- 244000197580 Poria cocos Species 0.000 claims abstract description 15
- 235000008599 Poria cocos Nutrition 0.000 claims abstract description 15
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 16
- 235000019441 ethanol Nutrition 0.000 claims description 8
- 239000000047 product Substances 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 7
- 239000000706 filtrate Substances 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 5
- 238000003756 stirring Methods 0.000 claims description 4
- 241000131329 Carabidae Species 0.000 claims description 3
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims description 2
- 235000003140 Panax quinquefolius Nutrition 0.000 claims description 2
- 239000003937 drug carrier Substances 0.000 claims description 2
- 235000008434 ginseng Nutrition 0.000 claims description 2
- 241000345998 Calamus manan Species 0.000 claims 1
- 235000012950 rattan cane Nutrition 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 9
- 238000009472 formulation Methods 0.000 abstract description 3
- 201000010099 disease Diseases 0.000 description 8
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 8
- 241001251949 Xanthium sibiricum Species 0.000 description 4
- 235000015096 spirit Nutrition 0.000 description 4
- 229940079593 drug Drugs 0.000 description 3
- 201000010934 exostosis Diseases 0.000 description 3
- 201000010930 hyperostosis Diseases 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 244000170916 Paeonia officinalis Species 0.000 description 2
- 235000006484 Paeonia officinalis Nutrition 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 244000241257 Cucumis melo Species 0.000 description 1
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 1
- 241000785585 Gryllotalpa africana Species 0.000 description 1
- 241000066370 Gryllotalpa unispina Species 0.000 description 1
- 240000005809 Prunus persica Species 0.000 description 1
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
- 238000001467 acupuncture Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 238000011443 conventional therapy Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 238000003359 percent control normalization Methods 0.000 description 1
- 238000000053 physical method Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 208000029761 vertebral disease Diseases 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/24—Mucus; Mucous glands; Bursa; Synovial fluid; Arthral fluid; Excreta; Spinal fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/55—Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A61K36/12—Filicopsida or Pteridopsida
- A61K36/126—Drynaria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/51—Gentianaceae (Gentian family)
- A61K36/515—Gentiana
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/634—Forsythia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/732—Chaenomeles, e.g. flowering quince
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
- A61K36/855—Clerodendrum, e.g. glorybower
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Insects & Arthropods (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to tcm field, specially a kind of Chinese medicine composition and preparation method thereof for treating cervical spondylosis, protrusion of lumber intervertebral disc, osteoproliferation.The Chinese medicine composition is prepared by following raw material components:Safflower, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, frankincense, Rhizoma Chuanxiong, mole cricket, excrementum pteropi, ground bettle, corydalis tuber, dragon's blood, earthworm, teasel root, the rhizome of davallia, peach kernel, Radix Curcumae, radix paeoniae rubra, the root of bidentate achyranthes, myrrh, the root bark of Chinese wolf-berry, pawpaw, the dried immature fruit of citron orange, Radix Paeoniae Alba, Fructus Forsythiae, pseudo-ginseng, Ramulus Taxilli, uncaria, Radix Angelicae Pubescentis, bark of ash, windproof, Radix Glycyrrhizae, Radix Codonopsis, cassia twig, banyan palpus, Cortex Eucommiae, Poria cocos, radix rehmanniae preparata, Radix zanthoxyli, senior general, Moschus.Inventive formulation is scientific and reasonable, and each component cooperates with compatibility, fine curative effect is all had to cervical spondylosis, protrusion of lumber intervertebral disc, osteoproliferation, total effective rate is obviously shortened treatment cycle up to 95% or more.
Description
【Technical field】
The present invention relates to tcm fields, and in particular to a kind of to treat in cervical spondylosis, protrusion of lumber intervertebral disc, osteoproliferation
Drug composition and preparation method thereof.
【Background technology】
Cervical spondylosis, protrusion of lumber intervertebral disc, osteoproliferation are all current common diseases, and are relatively obstinate diseases,
Disease treatment difficulty is big, treatment cycle is long for these, is easy recurrence, and severe patient's some even causes life-long disabilities, influences patient health
With normal life and work.It treats there are three types of the current conventional therapies of the above illness:First, physical method, this method is used and is pressed
Rub, acupuncture, medical instrument traction therapeutic etc., this method is only applicable to the slight waist dish outstanding patient of symptom;Second is that operation
Treatment, this medical expense is high, risk is big, and is easy recurrence;Third, drug therapy, with some are promoting blood circulation and removing blood stasis currently on the market
Oral medicinal herb washout, impregnate, curative effect has such or such insufficient and less notable, some medication times are long, control
More rate is low, cannot fundamentally dispel illness.
Although can be treated on existing market cervical spondylosis, protrusion of lumber intervertebral disc, osteoproliferation Chinese medicine composition type compared with
It is more, but many effects are not notable.Such as application number CN201711212431.4 treatments cervical spondylosis, protrusion of lumber intervertebral disc, hyperostosis
Raw Chinese medicine composition and its preparation method, although the Chinese medicine composition being prepared is effective, the course for the treatment of is long in practical application, treatment
It is efficient low.
【Invention content】
The goal of the invention of the present invention is:In view of the deficiencies of the prior art, provide that a kind of to treat cervical spondylosis, lumber ertebral disc prominent
Go out, the Chinese medicine composition and preparation method thereof of osteoproliferation;Inventive formulation is scientific and reasonable, and each component cooperates with compatibility, to cervical vertebra
Disease, protrusion of lumber intervertebral disc, osteoproliferation all have fine curative effect, and total effective rate is obviously shortened treatment week up to 95% or more
Phase.
To achieve the goals above, the technical solution adopted by the present invention is as follows:
A kind of Chinese medicine composition for treating cervical spondylosis, protrusion of lumber intervertebral disc, osteoproliferation, by following raw material components preparation
At:Safflower, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, frankincense, Rhizoma Chuanxiong, mole cricket, excrementum pteropi, ground bettle, corydalis tuber, dragon's blood, earthworm, teasel root, the rhizome of davallia,
Peach kernel, Radix Curcumae, radix paeoniae rubra, the root of bidentate achyranthes, myrrh, the root bark of Chinese wolf-berry, pawpaw, the dried immature fruit of citron orange, Radix Paeoniae Alba, Fructus Forsythiae, pseudo-ginseng, Ramulus Taxilli, uncaria, Radix Angelicae Pubescentis, the Qin
Macrophylla, windproof, Radix Glycyrrhizae, Radix Codonopsis, cassia twig, banyan palpus, Cortex Eucommiae, Poria cocos, radix rehmanniae preparata, Radix zanthoxyli, senior general, Moschus.
Further, it is prepared by the raw material components of following weight parts:80-120 parts of safflower, 180-220 parts of Radix Angelicae Sinensis, pellet
Ginseng 20-60 parts, 20-60 parts of frankincense, 180-220 parts of Rhizoma Chuanxiong, 10-30 parts of mole cricket, 20-50 parts of excrementum pteropi, 10-30 parts of ground bettle,
80-120 parts of corydalis tuber, 180-220 parts of dragon's blood, 20-50 parts of earthworm, 20-60 parts of teasel root, 20-50 parts of the rhizome of davallia, peach kernel 20-60
Part, 20-50 parts of Radix Curcumae, 20-60 parts of radix paeoniae rubra, 20-60 parts of the root of bidentate achyranthes, 20-60 parts of myrrh, 20-60 parts of the root bark of Chinese wolf-berry, 5-15 parts of pawpaw,
15-50 parts of the dried immature fruit of citron orange, 5-15 parts of Radix Paeoniae Alba, 10-30 parts of Fructus Forsythiae, 5-20 parts of pseudo-ginseng, 15-50 parts of Ramulus Taxilli, 10-30 parts of uncaria, Radix Angelicae Pubescentis
20-50 parts, 10-30 parts of bark of ash, 10-30 parts windproof, 10-30 parts of Radix Glycyrrhizae, 30-50 parts of Radix Codonopsis, 30-50 parts of cassia twig, banyan must 80-
120 parts, 20-50 parts of Cortex Eucommiae, 5-25 parts of Poria cocos, 5-15 parts of radix rehmanniae preparata, 80-120 parts of Radix zanthoxyli, 30-80 parts of senior general, Moschus
0.01-0.05 parts.
Preferably, it is prepared by the raw material components of following weight parts:100 parts of safflower, 200 parts of Radix Angelicae Sinensis, 40 parts of Radix Salviae Miltiorrhizae, breast
40 parts fragrant, 200 parts of Rhizoma Chuanxiong, 20 parts of mole cricket, 30 parts of excrementum pteropi, 20 parts of ground bettle, 100 parts of corydalis tuber, 200 parts of dragon's blood, earthworm 30
Part, 40 parts of teasel root, 30 parts of the rhizome of davallia, 40 parts of peach kernel, 30 parts of Radix Curcumae, 40 parts of radix paeoniae rubra, 40 parts of the root of bidentate achyranthes, 40 parts of myrrh, the root bark of Chinese wolf-berry 40
Part, 10 parts of pawpaw, 35 parts of the dried immature fruit of citron orange, 10 parts of Radix Paeoniae Alba, 20 parts of Fructus Forsythiae, 15 parts of pseudo-ginseng, 35 parts of Ramulus Taxilli, 20 parts of uncaria, 30 parts of Radix Angelicae Pubescentis,
20 parts of bark of ash, 20 parts windproof, 20 parts of Radix Glycyrrhizae, 40 parts of Radix Codonopsis, 40 parts of cassia twig, banyan must 100 parts, it is 30 parts of Cortex Eucommiae, 15 parts of Poria cocos, ripe
10 parts of ground, 100 parts of Radix zanthoxyli, 50 parts of senior general, 0.025 part of Moschus.
The present invention provides above-mentioned treatment cervical spondylosis, protrusion of lumber intervertebral disc, osteoproliferation Chinese medicine composition preparation side
Method, which is characterized in that include the following steps:
(1) raw material is weighed respectively by parts by weight of raw materials:Safflower, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, frankincense, Rhizoma Chuanxiong, mole cricket, excrementum pteropi, ground beetle
It is worm, corydalis tuber, dragon's blood, earthworm, teasel root, the rhizome of davallia, peach kernel, Radix Curcumae, radix paeoniae rubra, the root of bidentate achyranthes, myrrh, the root bark of Chinese wolf-berry, pawpaw, the dried immature fruit of citron orange, white
Chinese herbaceous peony, Fructus Forsythiae, pseudo-ginseng, Ramulus Taxilli, uncaria, Radix Angelicae Pubescentis, bark of ash, windproof, Radix Glycyrrhizae, Radix Codonopsis, cassia twig, banyan palpus, Cortex Eucommiae, Poria cocos, radix rehmanniae preparata,
Radix zanthoxyli, senior general, Moschus;Mechanical crushing is spare;
(2) by obtained by step (1) product be added volume fraction be 42%-45% ethyl alcohol, stir evenly to get.
The present invention also provides treatment cervical spondylosis, protrusion of lumber intervertebral disc, osteoproliferation Chinese medicine composition preparation method,
It is characterized by comprising the following steps:
(1) raw material is weighed respectively by parts by weight of raw materials:Safflower, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, frankincense, Rhizoma Chuanxiong, mole cricket, excrementum pteropi, ground beetle
It is worm, corydalis tuber, dragon's blood, earthworm, teasel root, the rhizome of davallia, peach kernel, Radix Curcumae, radix paeoniae rubra, the root of bidentate achyranthes, myrrh, the root bark of Chinese wolf-berry, pawpaw, the dried immature fruit of citron orange, white
Chinese herbaceous peony, Fructus Forsythiae, pseudo-ginseng, Ramulus Taxilli, uncaria, Radix Angelicae Pubescentis, bark of ash, windproof, Radix Glycyrrhizae, Radix Codonopsis, cassia twig, banyan palpus, Cortex Eucommiae, Poria cocos, radix rehmanniae preparata,
Radix zanthoxyli, senior general, Moschus;Mechanical crushing is spare;
(2) ethyl alcohol that volume fraction is 42%-45% is added in the product obtained by step (1), stirs evenly, soaks at room temperature
Bubble 20-30 days, filtering, filtrate is concentrated and dried at 70 DEG C, crushing to get.
A kind of Chinese medicine preparation for treating cervical spondylosis, protrusion of lumber intervertebral disc, osteoproliferation, by a effective amount of of the present invention
Chinese medicine composition and pharmaceutically acceptable carrier composition prepared by Chinese medicine composition or the method for the invention.
Further, the Chinese medicine preparation is externally used paste.
Mole cricket of the present invention is Chinese medicine mole cricket, i.e. Gryllotalpidae insect mole cricket Gryllotalpa africana
The adult of Palisot et Beaurois or big mole cricket G.unispina Saussure is all.
In conclusion by adopting the above-described technical solution, the beneficial effects of the invention are as follows:
Inventive formulation is scientific and reasonable, and each component cooperates with compatibility, has to cervical spondylosis, protrusion of lumber intervertebral disc, osteoproliferation
There is fine curative effect, total effective rate is obviously shortened treatment cycle up to 95% or more, and preparation method is simple and easy to do, stable quality,
It is easy to use, it works rapid, is worth clinical application.
【Specific implementation mode】
Embodiment 1
Prescription is prepared by the raw material components of following weight parts:100 parts of safflower, 200 parts of Radix Angelicae Sinensis, 40 parts of Radix Salviae Miltiorrhizae, frankincense
40 parts, 200 parts of Rhizoma Chuanxiong, 20 parts of mole cricket, 30 parts of excrementum pteropi, 20 parts of ground bettle, 100 parts of corydalis tuber, 200 parts of dragon's blood, 30 parts of earthworm,
40 parts of teasel root, 30 parts of the rhizome of davallia, 40 parts of peach kernel, 30 parts of Radix Curcumae, 40 parts of radix paeoniae rubra, 40 parts of the root of bidentate achyranthes, 40 parts of myrrh, 40 parts of the root bark of Chinese wolf-berry,
10 parts of pawpaw, 35 parts of the dried immature fruit of citron orange, 10 parts of Radix Paeoniae Alba, 20 parts of Fructus Forsythiae, 15 parts of pseudo-ginseng, 35 parts of Ramulus Taxilli, 20 parts of uncaria, 30 parts of Radix Angelicae Pubescentis, the Qin
20 parts of Macrophylla, 20 parts windproof, 20 parts of Radix Glycyrrhizae, 40 parts of Radix Codonopsis, 40 parts of cassia twig, 100 parts of banyan palpus, 30 parts of Cortex Eucommiae, 15 parts of Poria cocos, radix rehmanniae preparata
10 parts, 100 parts of Radix zanthoxyli, 50 parts of senior general, 0.025 part of Moschus.
Preparation method:(1) raw material is weighed respectively by parts by weight of raw materials:Safflower, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, frankincense, Rhizoma Chuanxiong, mole cricket, five spirits
Fat, ground bettle, corydalis tuber, dragon's blood, earthworm, teasel root, the rhizome of davallia, peach kernel, Radix Curcumae, radix paeoniae rubra, the root of bidentate achyranthes, myrrh, the root bark of Chinese wolf-berry, pawpaw,
The dried immature fruit of citron orange, Radix Paeoniae Alba, Fructus Forsythiae, pseudo-ginseng, Ramulus Taxilli, uncaria, Radix Angelicae Pubescentis, bark of ash, windproof, Radix Glycyrrhizae, Radix Codonopsis, cassia twig, banyan palpus, Cortex Eucommiae, Fu
Siberian cocklebur, radix rehmanniae preparata, Radix zanthoxyli, senior general, Moschus;Mechanical crushing is spare;
(2) ethyl alcohol that the volume fraction of 5000 parts by weight is 45% is added in the product obtained by step (1), stirred evenly,
To obtain the final product.It is applied with for affected part.
Embodiment 2
Prescription is prepared by the raw material components of following weight parts:80 parts of safflower, 180 parts of Radix Angelicae Sinensis, 20 parts of Radix Salviae Miltiorrhizae, frankincense 20
Part, 10 parts of mole cricket, 20 parts of excrementum pteropi, 10 parts of ground bettle, 80 parts of corydalis tuber, 180 parts of dragon's blood, 20 parts of earthworm, continues at 180 parts of Rhizoma Chuanxiong
20 parts disconnected, 20 parts of the rhizome of davallia, 20 parts of peach kernel, 20 parts of Radix Curcumae, 20 parts of radix paeoniae rubra, 20 parts of the root of bidentate achyranthes, 20 parts of myrrh, 20 parts of the root bark of Chinese wolf-berry, wood
5 parts of melon, 15 parts of the dried immature fruit of citron orange, 5 parts of Radix Paeoniae Alba, 10 parts of Fructus Forsythiae, 5 parts of pseudo-ginseng, 15 parts of Ramulus Taxilli, 10 parts of uncaria, 20 parts of Radix Angelicae Pubescentis, bark of ash 10
Part, 10 parts windproof, 10 parts of Radix Glycyrrhizae, 30 parts of Radix Codonopsis, 30 parts of cassia twig, 80 parts of banyan palpus, 20 parts of Cortex Eucommiae, 5 parts of Poria cocos, 5 parts of radix rehmanniae preparata, two
80 parts of face needle, 30 parts of senior general, 0.01 part of Moschus.
Preparation method:(1) raw material is weighed respectively by parts by weight of raw materials:Safflower, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, frankincense, Rhizoma Chuanxiong, mole cricket, five spirits
Fat, ground bettle, corydalis tuber, dragon's blood, earthworm, teasel root, the rhizome of davallia, peach kernel, Radix Curcumae, radix paeoniae rubra, the root of bidentate achyranthes, myrrh, the root bark of Chinese wolf-berry, pawpaw,
The dried immature fruit of citron orange, Radix Paeoniae Alba, Fructus Forsythiae, pseudo-ginseng, Ramulus Taxilli, uncaria, Radix Angelicae Pubescentis, bark of ash, windproof, Radix Glycyrrhizae, Radix Codonopsis, cassia twig, banyan palpus, Cortex Eucommiae, Fu
Siberian cocklebur, radix rehmanniae preparata, Radix zanthoxyli, senior general, Moschus;Mechanical crushing is spare;
(2) ethyl alcohol that the volume fraction of 4000 parts by weight is 42% is added in the product obtained by step (1), stirred evenly,
It impregnates 20 days at room temperature, filtering, filtrate is concentrated and dried at 70 DEG C, crushes, auxiliary material is then added, externally used paste is made.For
It is applied in disease sites.
Embodiment 3
Prescription is prepared by the raw material components of following weight parts:120 parts of safflower, 220 parts of Radix Angelicae Sinensis, 60 parts of Radix Salviae Miltiorrhizae, frankincense
60 parts, 220 parts of Rhizoma Chuanxiong, 30 parts of mole cricket, 50 parts of excrementum pteropi, 30 parts of ground bettle, 120 parts of corydalis tuber, 220 parts of dragon's blood, 50 parts of earthworm,
60 parts of teasel root, 50 parts of the rhizome of davallia, 60 parts of peach kernel, 50 parts of Radix Curcumae, 60 parts of radix paeoniae rubra, 60 parts of the root of bidentate achyranthes, 60 parts of myrrh, 60 parts of the root bark of Chinese wolf-berry,
15 parts of pawpaw, 50 parts of the dried immature fruit of citron orange, 15 parts of Radix Paeoniae Alba, 30 parts of Fructus Forsythiae, 20 parts of pseudo-ginseng, 50 parts of Ramulus Taxilli, 30 parts of uncaria, 50 parts of Radix Angelicae Pubescentis, the Qin
30 parts of Macrophylla, 30 parts windproof, 30 parts of Radix Glycyrrhizae, 50 parts of Radix Codonopsis, 50 parts of cassia twig, 120 parts of banyan palpus, 50 parts of Cortex Eucommiae, 25 parts of Poria cocos, radix rehmanniae preparata
15 parts, 120 parts of Radix zanthoxyli, 80 parts of senior general, 0.05 part of Moschus.
Preparation method:(1) raw material is weighed respectively by parts by weight of raw materials:Safflower, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, frankincense, Rhizoma Chuanxiong, mole cricket, five spirits
Fat, ground bettle, corydalis tuber, dragon's blood, earthworm, teasel root, the rhizome of davallia, peach kernel, Radix Curcumae, radix paeoniae rubra, the root of bidentate achyranthes, myrrh, the root bark of Chinese wolf-berry, pawpaw,
The dried immature fruit of citron orange, Radix Paeoniae Alba, Fructus Forsythiae, pseudo-ginseng, Ramulus Taxilli, uncaria, Radix Angelicae Pubescentis, bark of ash, windproof, Radix Glycyrrhizae, Radix Codonopsis, cassia twig, banyan palpus, Cortex Eucommiae, Fu
Siberian cocklebur, radix rehmanniae preparata, Radix zanthoxyli, senior general, Moschus;Mechanical crushing is spare;
(2) ethyl alcohol that the volume fraction of 7000 parts by weight is 43% is added in the product obtained by step (1), stirred evenly,
It impregnates 30 days at room temperature, filtering, filtrate is concentrated and dried at 70 DEG C, crushes, auxiliary material is then added, externally used paste is made.For
It is applied in disease sites.
Embodiment 4
Prescription is prepared by the raw material components of following weight parts:100 parts of safflower, 200 parts of Radix Angelicae Sinensis, 40 parts of Radix Salviae Miltiorrhizae, frankincense
40 parts, 200 parts of Rhizoma Chuanxiong, 20 parts of mole cricket, 30 parts of excrementum pteropi, 20 parts of ground bettle, 100 parts of corydalis tuber, 200 parts of dragon's blood, 30 parts of earthworm,
40 parts of teasel root, 30 parts of the rhizome of davallia, 40 parts of peach kernel, 30 parts of Radix Curcumae, 40 parts of radix paeoniae rubra, 40 parts of the root of bidentate achyranthes, 40 parts of myrrh, 40 parts of the root bark of Chinese wolf-berry,
10 parts of pawpaw, 35 parts of the dried immature fruit of citron orange, 10 parts of Radix Paeoniae Alba, 20 parts of Fructus Forsythiae, 15 parts of pseudo-ginseng, 35 parts of Ramulus Taxilli, 20 parts of uncaria, 30 parts of Radix Angelicae Pubescentis, the Qin
20 parts of Macrophylla, 20 parts windproof, 20 parts of Radix Glycyrrhizae, 40 parts of Radix Codonopsis, 40 parts of cassia twig, 100 parts of banyan palpus, 30 parts of Cortex Eucommiae, 15 parts of Poria cocos, radix rehmanniae preparata
10 parts, 100 parts of Radix zanthoxyli, 50 parts of senior general, 0.025 part of Moschus.
Preparation method:(1) raw material is weighed respectively by parts by weight of raw materials:Safflower, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, frankincense, Rhizoma Chuanxiong, mole cricket, five spirits
Fat, ground bettle, corydalis tuber, dragon's blood, earthworm, teasel root, the rhizome of davallia, peach kernel, Radix Curcumae, radix paeoniae rubra, the root of bidentate achyranthes, myrrh, the root bark of Chinese wolf-berry, pawpaw,
The dried immature fruit of citron orange, Radix Paeoniae Alba, Fructus Forsythiae, pseudo-ginseng, Ramulus Taxilli, uncaria, Radix Angelicae Pubescentis, bark of ash, windproof, Radix Glycyrrhizae, Radix Codonopsis, cassia twig, banyan palpus, Cortex Eucommiae, Fu
Siberian cocklebur, radix rehmanniae preparata, Radix zanthoxyli, senior general, Moschus;Mechanical crushing is spare;
(2) ethyl alcohol that the volume fraction of 6000 parts by weight is 44% is added in the product obtained by step (1), stirred evenly,
It impregnates 25 days at room temperature, filtering, filtrate is concentrated and dried at 70 DEG C, crushes, auxiliary material is then added, externally used paste is made.For
It is applied in disease sites.
The effect of 1 present invention treatment cervical spondylosis of experimental example, protrusion of lumber intervertebral disc, osteoproliferation
1. general information:In clinical trial, 500 patients, age 16-70 Sui are selected, average age is 32 years old, wherein
Cervical spondylosis 200, the protrasion of the lumbar intervertebral disci 150, hyperostosis 150 are randomly divided into 5 groups, wherein 4 groups for the treatment of group, right
There is cervical spondylosis 40 in 1 group, every group according to organizing, the protrasion of the lumbar intervertebral disci 30, osteoproliferation 30.
2. case selection:(1) diagnostic criteria:According to State Administration of Traditional Chinese Medicine《Chinese medical disease Standardization of diagnosis and curative effect》Remembered
The cervical spondylosis of load, the protrasion of the lumbar intervertebral disci, hyperostosis.
3. therapy:The Chinese medicine preparation that treatment group 1-4 is prepared using 1-4 of the embodiment of the present invention respectively, is externally applied to
Affected part;
Control group gives Traditional Chinese medicine composition paste disclosed in CN201711212431.4.
Treatment group and control group administration are 2 times a day 10 days courses for the treatment of.
4. efficacy determination:Foundation《Chinese medical disease Standardization of diagnosis and curative effect》,
Recovery from illness:Illness all disappears after treatment, reaches clinical cure standard;
It is effective:State of an illness sign is obviously improved after treatment;
Effectively:State of an illness sign makes moderate progress after treatment;
In vain:It is unchanged before and after treatment.
5. treatment results:After 1 course for the treatment of, treatment results are as shown in table 1:
1 treatment group of table and control group therapeutic effect compare
Group | It fully recovers (example) | Effective (example) | Effectively (example) | (example) in vain | Total effective rate |
Treatment group 1 | 22 | 36 | 42 | 0 | 100.0% |
Treatment group 2 | 29 | 28 | 39 | 4 | 96.0% |
Treatment group 3 | 19 | 31 | 45 | 5 | 95.0% |
Treatment group 4 | 28 | 30 | 40 | 2 | 98.0% |
Control group | 6 | 27 | 48 | 19 | 81% |
Conclusion:(1) prescription of the present invention is scientific and reasonable, and preparation method is simple and easy to do, and stable quality is easy to use;(2) this hair
A bright course for the treatment of only needs to can reach within 10 days 95% or more treated effect, hence it is evident that shortens treatment cycle.
Above description is the detailed description for the present invention preferably possible embodiments, but embodiment is not limited to this hair
Bright patent claim, it is all the present invention suggested by technical spirit under completed same changes or modifications change, should all belong to
In the covered the scope of the claims of the present invention.
Claims (7)
1. a kind of Chinese medicine composition for treating cervical spondylosis, protrusion of lumber intervertebral disc, osteoproliferation, which is characterized in that by following raw materials
Component is prepared:Safflower, Radix Salviae Miltiorrhizae, frankincense, Rhizoma Chuanxiong, mole cricket, excrementum pteropi, ground bettle, corydalis tuber, dragon's blood, earthworm, continues at Radix Angelicae Sinensis
Disconnected, the rhizome of davallia, peach kernel, Radix Curcumae, radix paeoniae rubra, the root of bidentate achyranthes, myrrh, the root bark of Chinese wolf-berry, pawpaw, the dried immature fruit of citron orange, Radix Paeoniae Alba, Fructus Forsythiae, pseudo-ginseng, Ramulus Taxilli, hook
Rattan, Radix Angelicae Pubescentis, bark of ash, windproof, Radix Glycyrrhizae, Radix Codonopsis, cassia twig, banyan palpus, Cortex Eucommiae, Poria cocos, radix rehmanniae preparata, Radix zanthoxyli, senior general, Moschus.
2. Chinese medicine composition according to claim 1, which is characterized in that by the raw material components preparation of following weight parts
At:80-120 parts of safflower, 180-220 parts of Radix Angelicae Sinensis, 20-60 parts of Radix Salviae Miltiorrhizae, 20-60 parts of frankincense, 180-220 parts of Rhizoma Chuanxiong, mole cricket 10-30
Part, 20-50 parts of excrementum pteropi, 10-30 parts of ground bettle, 80-120 parts of corydalis tuber, 180-220 parts of dragon's blood, 20-50 parts of earthworm, teasel root
20-60 parts, 20-50 parts of the rhizome of davallia, 20-60 parts of peach kernel, 20-50 parts of Radix Curcumae, 20-60 parts of radix paeoniae rubra, 20-60 parts of the root of bidentate achyranthes, myrrh 20-
60 parts, 20-60 parts of the root bark of Chinese wolf-berry, 5-15 parts of pawpaw, 15-50 parts of the dried immature fruit of citron orange, 5-15 parts of Radix Paeoniae Alba, 10-30 parts of Fructus Forsythiae, 5-20 parts of pseudo-ginseng,
15-50 parts of Ramulus Taxilli, 10-30 parts of uncaria, 20-50 parts of Radix Angelicae Pubescentis, 10-30 parts of bark of ash, 10-30 parts windproof, 10-30 parts of Radix Glycyrrhizae, party
30-50 parts of ginseng, 30-50 parts of cassia twig, 80-120 parts of banyan palpus, 20-50 parts of Cortex Eucommiae, 5-25 parts of Poria cocos, 5-15 parts of radix rehmanniae preparata, Radix zanthoxyli
80-120 parts, 30-80 parts of senior general, 0.01-0.05 parts of Moschus.
3. Chinese medicine composition according to claim 1 or 2, which is characterized in that prepared by the raw material components of following weight parts
It forms:100 parts of safflower, 200 parts of Radix Angelicae Sinensis, 40 parts of Radix Salviae Miltiorrhizae, 40 parts of frankincense, 200 parts of Rhizoma Chuanxiong, 20 parts of mole cricket, 30 parts of excrementum pteropi, ground beetle
20 parts of worm, 100 parts of corydalis tuber, 200 parts of dragon's blood, 30 parts of earthworm, 40 parts of teasel root, 30 parts of the rhizome of davallia, 40 parts of peach kernel, 30 parts of Radix Curcumae,
40 parts of radix paeoniae rubra, 40 parts of the root of bidentate achyranthes, 40 parts of myrrh, 40 parts of the root bark of Chinese wolf-berry, 10 parts of pawpaw, 35 parts of the dried immature fruit of citron orange, 10 parts of Radix Paeoniae Alba, 20 parts of Fructus Forsythiae, field
7 15 parts, 35 parts of Ramulus Taxilli, 20 parts of uncaria, 30 parts of Radix Angelicae Pubescentis, 20 parts of bark of ash, 20 parts windproof, 20 parts of Radix Glycyrrhizae, 40 parts of Radix Codonopsis, cassia twig
40 parts, banyan must 100 parts, 30 parts of Cortex Eucommiae, 15 parts of Poria cocos, 10 parts of radix rehmanniae preparata, 100 parts of Radix zanthoxyli, 50 parts of senior general, Moschus 0.025
Part.
4. the preparation of the Chinese medicine composition of any one of the claim 1-3 treatment cervical spondylosiss, protrusion of lumber intervertebral disc, osteoproliferation
Method, which is characterized in that include the following steps:
(1) raw material is weighed respectively by parts by weight of raw materials:Safflower, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, frankincense, Rhizoma Chuanxiong, mole cricket, excrementum pteropi, ground bettle,
Corydalis tuber, dragon's blood, earthworm, teasel root, the rhizome of davallia, peach kernel, Radix Curcumae, radix paeoniae rubra, the root of bidentate achyranthes, myrrh, the root bark of Chinese wolf-berry, pawpaw, the dried immature fruit of citron orange, Radix Paeoniae Alba,
Fructus Forsythiae, pseudo-ginseng, Ramulus Taxilli, uncaria, Radix Angelicae Pubescentis, bark of ash, windproof, Radix Glycyrrhizae, Radix Codonopsis, cassia twig, banyan palpus, Cortex Eucommiae, Poria cocos, radix rehmanniae preparata, two
Face needle, senior general, Moschus;Mechanical crushing is spare;
(2) by obtained by step (1) product be added volume fraction be 42%-45% ethyl alcohol, stir evenly to get.
5. the preparation of the Chinese medicine composition of any one of the claim 1-3 treatment cervical spondylosiss, protrusion of lumber intervertebral disc, osteoproliferation
Method, which is characterized in that include the following steps:
(1) raw material is weighed respectively by parts by weight of raw materials:Safflower, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, frankincense, Rhizoma Chuanxiong, mole cricket, excrementum pteropi, ground bettle,
Corydalis tuber, dragon's blood, earthworm, teasel root, the rhizome of davallia, peach kernel, Radix Curcumae, radix paeoniae rubra, the root of bidentate achyranthes, myrrh, the root bark of Chinese wolf-berry, pawpaw, the dried immature fruit of citron orange, Radix Paeoniae Alba,
Fructus Forsythiae, pseudo-ginseng, Ramulus Taxilli, uncaria, Radix Angelicae Pubescentis, bark of ash, windproof, Radix Glycyrrhizae, Radix Codonopsis, cassia twig, banyan palpus, Cortex Eucommiae, Poria cocos, radix rehmanniae preparata, two
Face needle, senior general, Moschus;Mechanical crushing is spare;
(2) ethyl alcohol that volume fraction is 42%-45% is added in the product obtained by step (1), stirs evenly, impregnates at room temperature
20-30 days, filtering, filtrate was concentrated and dried at 70 DEG C, crush to get.
6. a kind of Chinese medicine preparation for treating cervical spondylosis, protrusion of lumber intervertebral disc, osteoproliferation, which is characterized in that by a effective amount of power
Profit requires Chinese medicine composition prepared by any one of 1~3 any one of them Chinese medicine composition or claim 4~5 the method
It is formed with pharmaceutically acceptable carrier.
7. Chinese medicine preparation according to claim 6, which is characterized in that the Chinese medicine preparation is externally used paste.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810858299.2A CN108704104A (en) | 2018-07-31 | 2018-07-31 | A kind of Chinese medicine composition and preparation method thereof for treating cervical spondylosis, protrusion of lumber intervertebral disc, osteoproliferation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810858299.2A CN108704104A (en) | 2018-07-31 | 2018-07-31 | A kind of Chinese medicine composition and preparation method thereof for treating cervical spondylosis, protrusion of lumber intervertebral disc, osteoproliferation |
Publications (1)
Publication Number | Publication Date |
---|---|
CN108704104A true CN108704104A (en) | 2018-10-26 |
Family
ID=63875508
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810858299.2A Pending CN108704104A (en) | 2018-07-31 | 2018-07-31 | A kind of Chinese medicine composition and preparation method thereof for treating cervical spondylosis, protrusion of lumber intervertebral disc, osteoproliferation |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN108704104A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT201800020053A1 (en) * | 2018-12-18 | 2020-06-18 | Shanghai Boling Man Cosmetic Co Ltd | Drug for the treatment of shoulder periarthritis and method for its preparation |
CN112546145A (en) * | 2020-11-19 | 2021-03-26 | 湖南兰嗅生物科技有限公司 | Spur removing paste and preparation method thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102000276A (en) * | 2010-11-15 | 2011-04-06 | 李清珠 | External plaster for promoting blood circulation and removing blood stasis and preparation method thereof |
CN105381417A (en) * | 2015-12-25 | 2016-03-09 | 沙孝银 | Traditional Chinese medicine external-treatment orthopaedic plaster |
-
2018
- 2018-07-31 CN CN201810858299.2A patent/CN108704104A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102000276A (en) * | 2010-11-15 | 2011-04-06 | 李清珠 | External plaster for promoting blood circulation and removing blood stasis and preparation method thereof |
CN105381417A (en) * | 2015-12-25 | 2016-03-09 | 沙孝银 | Traditional Chinese medicine external-treatment orthopaedic plaster |
Non-Patent Citations (1)
Title |
---|
胡宏中: ""加味独活寄生汤为主治疗颈椎病43例"", 《安徽中医学院学报》 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT201800020053A1 (en) * | 2018-12-18 | 2020-06-18 | Shanghai Boling Man Cosmetic Co Ltd | Drug for the treatment of shoulder periarthritis and method for its preparation |
CN112546145A (en) * | 2020-11-19 | 2021-03-26 | 湖南兰嗅生物科技有限公司 | Spur removing paste and preparation method thereof |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN101284121B (en) | Combination medicine for curing the hoary hair | |
CN1315457C (en) | Bath lotion for chilblain nursing and preparation method thereof | |
CN103705878B (en) | One treats migraine Chinese medicine preparation | |
CN108704104A (en) | A kind of Chinese medicine composition and preparation method thereof for treating cervical spondylosis, protrusion of lumber intervertebral disc, osteoproliferation | |
CN101156933B (en) | A medicine for treating cerebrovascular disease | |
CN114177251A (en) | Traditional Chinese medicine composition for preventing and treating rheumatism, health wine and preparation method thereof | |
CN101249184B (en) | Medicine for treating osteoproliferation as well as its preparation method | |
CN102698214B (en) | Traditional Chinese medicine for treating migraine and preparation method thereof | |
CN1089854A (en) | Wet dressing quick-acting antidiarrheal medicine | |
CN103656239B (en) | A kind of Chinese drugs agentia for the treatment of wind syndrome of head and preparation method thereof | |
CN103393954B (en) | A kind of ointment preparation method for rehabilitation after common peroneal nerve injury | |
CN110302269A (en) | A kind of warming and activating meridian foot-soaking liquid | |
CN105617198A (en) | Method for preparing medicinal liquor for treating wind-cold low back pain | |
CN101229224B (en) | Chinese traditional medicine ointment preparation for curing vitligo and preparing method thereof | |
CN109106883A (en) | A kind of pharmaceutical composition for treating eczema | |
CN104288604B (en) | A kind of Chinese medicine composition for treating cerebral infarction | |
CN103432333B (en) | Composition consisting of effective traditional Chinese medicine parts and used for treating hypothyroidism | |
CN101983712A (en) | Novel medicament for treating coronary heart disease | |
CN110251620B (en) | Traditional Chinese medicine composition for treating lumbar disc herniation and preparation method thereof | |
CN101953941B (en) | Chinese medicinal liquor for treating femoral head necrosis | |
CN101658661A (en) | Chinese medicinal composition having effect of promoting blood circulation and removing blood stasis | |
CN108210596B (en) | Traditional Chinese medicine for reducing blood pressure and method for preparing plaster for reducing blood pressure by using traditional Chinese medicine | |
CN105169288A (en) | Traditional Chinese medicine decoction for treating unclear speech of phlegm-damp collateral accumulation type cerebral infarction patient | |
CN105362817A (en) | Pharmaceutical composition for treating eczema | |
US20200046793A1 (en) | Itching water applicable to postoperative wound itching and a process for preparing it |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20181026 |
|
RJ01 | Rejection of invention patent application after publication |