CN108693011A - A kind of aobvious tape drums of chromosome N - Google Patents
A kind of aobvious tape drums of chromosome N Download PDFInfo
- Publication number
- CN108693011A CN108693011A CN201810455325.7A CN201810455325A CN108693011A CN 108693011 A CN108693011 A CN 108693011A CN 201810455325 A CN201810455325 A CN 201810455325A CN 108693011 A CN108693011 A CN 108693011A
- Authority
- CN
- China
- Prior art keywords
- protected
- light
- slide
- box body
- light box
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000000349 chromosome Anatomy 0.000 title claims abstract description 23
- 239000003153 chemical reaction reagent Substances 0.000 abstract description 9
- 230000000694 effects Effects 0.000 abstract description 8
- 238000000034 method Methods 0.000 description 7
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 6
- SQGYOTSLMSWVJD-UHFFFAOYSA-N silver(1+) nitrate Chemical compound [Ag+].[O-]N(=O)=O SQGYOTSLMSWVJD-UHFFFAOYSA-N 0.000 description 6
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 description 3
- 235000019253 formic acid Nutrition 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 229910001961 silver nitrate Inorganic materials 0.000 description 3
- 230000009466 transformation Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000004043 dyeing Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
- 229910017604 nitric acid Inorganic materials 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 238000007639 printing Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The present invention relates to a kind of chromosome N to show tape drum, including being protected from light box body and being protected from light box cover be protected from light box body fitted seal, it is protected from light box body and is flexibly connected by connector with being protected from light between box cover, multiple slide grooves for placing slide are arranged at intervals in the avoid light box body, one end is additionally provided with convenient for picking and placeing the little groove of slide in slide groove, the avoid light box, which covers, is provided with dripping hole, the quantity of dripping hole is identical as the quantity of slide groove, when being protected from light box cover and being closed, a dripping hole is corresponded to positioned at the top of a slide groove.The present invention has the following advantages:1. light-shading effect is more preferable, experiment success rate higher;2. effective prevent reagent volatilization, splash out, experimenter and environment are preferably protected;3. being spaced apart between slide, mutually it is not in contact with each other, can effectively avoids slide that mutually pollution occurs.
Description
Technical field
The present invention relates to a kind of chromosome N to show tape drum.
Background technology
Chromosome banding is also known as Chromosomes Banding or chromosome point dye, the cell risen since being the 1960s
Learn new technology.Common chromosome banding has Q bands, G bands, C bands, R bands, T bands, N bands, silver-colored band and high explanation band etc..All be by
Special handling procedure makes chromosome show the different colored zone of the depth.The aobvious band methods of N are that chromosome slice, thin piece is put in 60 DEG C of water-baths
In case, it is protected from light a kind of Banded method that the reagent prepared with formic acid and silver nitrate acts on poststaining.
Currently without the auxiliary device for being exclusively used in the aobvious band sample-addings of chromosome N and operating, the prior art be use a lid as
The lid for putting slide is put into water bath and is protected from light by slide carrier, and the reagent prepared with formic acid and silver nitrate drops in slide
On tested.This mode of operation has the following disadvantages:1, light-shading effect is bad, be easy to cause the failure of an experiment;2, reagent
Readily volatilized, spillage, it is unfavorable to the health and environment of experimenter;3, multiple slides are placed in lid together, slide
Between there is no a spacer, mutually pollution is easy between slide.
Invention content
The technical problem to be solved by the present invention is to:A kind of aobvious tape drums of chromosome N are provided, the aobvious tape drum light-shading effect is good, energy
It enough effectively prevent reagent volatilization, splash out, preferably protect experimenter and environment, be less likely to occur mutual dirt between slide
Dye, solves above-mentioned problems of the prior art.
Solving the technical solution of above-mentioned technical problem is:A kind of aobvious tape drums of chromosome N, including it is protected from light box body and and avoid light box
Body fitted seal is protected from light box cover, is protected from light box body and is flexibly connected by connector with being protected from light between box cover, described is protected from light box body
Multiple slide grooves for placing slide are inside arranged at intervals with, one end is additionally provided with convenient for picking and placeing the small of slide in slide groove
Groove, the avoid light box, which covers, is provided with dripping hole, and the quantity of dripping hole is identical as the quantity of slide groove, is protected from light box cover and is in
When closed state, a dripping hole is corresponded to positioned at the top of a slide groove.
It is described to be protected from light box body and avoid light box covers the snap component for being additionally provided with cooperation fastening.
The connector is hinge.
The slide groove is provided with 4-20.
The box body that is protected from light is black box body, and the box cover that is protected from light is black box cover.
Due to the adoption of the above technical scheme, the invention has the advantages that:
1. light-shading effect is more preferable, experiment success rate higher.Using the present invention, slide is positioned in the closed box body being protected from light and carries out
Sample-adding, effectively can avoid light from irradiating, light-shading effect is good, improves experiment success rate.
2. effective prevent reagent volatilization, splash out.Sample-adding process is carried out in closed environment, reagent cannot volatilize,
It splashes out outside box, preferably protects experimenter and environment, it is advantageous to the health and environmental protection of experimenter.
3. the slide groove of the present invention is interval setting, slide is individually positioned in different slide grooves, is loaded process
Slide will not remove slide groove, mutually be not in contact with each other between slide, can effectively avoid slide that mutually pollution occurs, further protect
The accuracy of experiment is demonstrate,proved.
4, the present invention is also provided in slide groove convenient for picking and placeing the little groove of slide, and experimenter's finger is put into small recessed
Slide can be easily put into or taken out in slot, and the loading or unloading operation of slide is very convenient quick.
In the following, the technical characteristic for showing tape drum to a kind of chromosome N of the present invention in conjunction with the accompanying drawings and embodiments is made further
Explanation.
Description of the drawings
Fig. 1:A kind of chromosome N of the present invention shows tape drum stereogram(It is in the open state to be protected from light box cover).
Fig. 2:A kind of chromosome N of the present invention shows tape drum stereogram(Box cover is protected from light to be closed).
Fig. 3:The A-A sectional views of Fig. 2(Amplification).
In figure:1- is protected from light box body, 11- slide grooves, 12- little grooves, 2- connectors, and 3- is protected from light box cover, 31- dripping holes,
4- snap components.
Specific implementation mode
Embodiment 1:A kind of aobvious tape drums of chromosome N as shown in Figure 1-Figure 3, including are protected from light box body 1 and coordinate with box body is protected from light
Sealing is protected from light box cover 3, is protected from light box body and is flexibly connected by connector 2 with being protected from light between box cover, in the avoid light box body between
Every being provided with 6 for placing the slide grooves 11 of slide, one end is additionally provided with convenient for picking and placeing the small recessed of slide in slide groove
Slot 12, the avoid light box, which covers, is provided with dripping hole 31, and the quantity of dripping hole is identical as the quantity of slide groove, is protected from light at box cover
When closed state, a dripping hole 31 is corresponded to positioned at the top of a slide groove 11.
It is described to be protected from light box body and avoid light box covers the snap component 4 for being additionally provided with cooperation fastening in the present embodiment.Described
The buckle structure that any type can fasten box body and box cover in the prior art may be used in snap component.As a kind of change
It changes, snap component can not also be set, the folding for being protected from light box body and being protected from light between box cover is controlled by connector.
In the present embodiment, the connector 2 is hinge.As a kind of transformation, the connector can also use other
Structure, as long as convenient for the folding for being protected from light box body and being protected from light between box cover.
In the present embodiment, the box body that is protected from light is black box body, and the box cover that is protected from light is black box cover, can preferably be played
Light-shading effect, is black after the effect of nitric acid argentum reagent, and printing and dyeing can also seem more clean and tidy up.It, can be with as a kind of transformation
Using the satisfactory box body of other light-shading effects and box cover.
As a kind of transformation of the present embodiment, the quantity of the slide groove can increase or subtract according to actual needs
Few, the quantity of general slide groove is set as 4-20, preferably 6-10.
Use process:Opening is protected from light box cover 3, and the slide with chromosome is sequentially placed into the slide groove for being protected from light box body 1
It in 11, is then shut off and is protected from light box cover, corresponding above slide at this time there are one dripping holes 31, and the present invention is put into 60 DEG C of water baths
In, by dripping hole by formic acid and the reagent dropwise to slide of silver nitrate preparation, completes N and show the operation with method.
Claims (5)
1. a kind of chromosome N shows tape drum, it is characterised in that:Including being protected from light box body(1)Be protected from light being protected from light for box body fitted seal
Box cover(3), it is protected from light box body and is protected from light between box cover and passes through connector(2)Flexible connection, the interior interval setting of the avoid light box body
There are multiple slide grooves for placing slide(11), one end is additionally provided with convenient for picking and placeing the little groove of slide in slide groove
(12), the avoid light box, which covers, is provided with dripping hole(31), the quantity of dripping hole is identical as the quantity of slide groove, is protected from light box cover
When being closed, a dripping hole(31)It is corresponding to be located at a slide groove(11)Top.
2. a kind of chromosome N according to claim 1 shows tape drum, it is characterised in that:It is described to be protected from light box body and be protected from light box cover
On be additionally provided with cooperation fastening snap component(4).
3. a kind of chromosome N according to claim 1 or 2 shows tape drum, it is characterised in that:The connector(2)It is hinge.
4. a kind of chromosome N according to claim 1 or 2 shows tape drum, it is characterised in that:The slide groove is provided with 4-
20.
5. a kind of chromosome N according to claim 1 or 2 shows tape drum, it is characterised in that:The box body that is protected from light is black box
Body, the box cover that is protected from light is black box cover.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810455325.7A CN108693011A (en) | 2018-05-14 | 2018-05-14 | A kind of aobvious tape drums of chromosome N |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810455325.7A CN108693011A (en) | 2018-05-14 | 2018-05-14 | A kind of aobvious tape drums of chromosome N |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108693011A true CN108693011A (en) | 2018-10-23 |
Family
ID=63847417
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810455325.7A Pending CN108693011A (en) | 2018-05-14 | 2018-05-14 | A kind of aobvious tape drums of chromosome N |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108693011A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110907256A (en) * | 2019-12-19 | 2020-03-24 | 广州达安临床检验中心有限公司 | Chromosome N banding method |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2292285Y (en) * | 1997-01-22 | 1998-09-23 | 庄建安 | Single sheet dying box for sample glass sheet |
| CN201930793U (en) * | 2010-12-28 | 2011-08-17 | 苏州浩欧博生物医药有限公司 | Moisturizing box for slide reaction |
| CN202162003U (en) * | 2011-07-26 | 2012-03-14 | 山东省立医院 | Humidor for medical experiments |
| CN203909039U (en) * | 2014-06-04 | 2014-10-29 | 大连医科大学 | Special immunochemistry developing box for cell climbing |
| CN105749995A (en) * | 2016-04-28 | 2016-07-13 | 宁波大学 | Biological chip hybrid device |
| CN205562561U (en) * | 2016-05-03 | 2016-09-07 | 四川农业大学 | Immunohistochemical wet box |
| WO2017076013A1 (en) * | 2015-11-03 | 2017-05-11 | 武汉康昕瑞基因健康科技有限公司 | Multi-channel sequencing reaction chamber and multi-channel sequencing reaction device |
| CN208399240U (en) * | 2018-05-14 | 2019-01-18 | 柳州市妇幼保健院 | A kind of aobvious tape drum of chromosome N |
-
2018
- 2018-05-14 CN CN201810455325.7A patent/CN108693011A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2292285Y (en) * | 1997-01-22 | 1998-09-23 | 庄建安 | Single sheet dying box for sample glass sheet |
| CN201930793U (en) * | 2010-12-28 | 2011-08-17 | 苏州浩欧博生物医药有限公司 | Moisturizing box for slide reaction |
| CN202162003U (en) * | 2011-07-26 | 2012-03-14 | 山东省立医院 | Humidor for medical experiments |
| CN203909039U (en) * | 2014-06-04 | 2014-10-29 | 大连医科大学 | Special immunochemistry developing box for cell climbing |
| WO2017076013A1 (en) * | 2015-11-03 | 2017-05-11 | 武汉康昕瑞基因健康科技有限公司 | Multi-channel sequencing reaction chamber and multi-channel sequencing reaction device |
| CN105749995A (en) * | 2016-04-28 | 2016-07-13 | 宁波大学 | Biological chip hybrid device |
| CN205562561U (en) * | 2016-05-03 | 2016-09-07 | 四川农业大学 | Immunohistochemical wet box |
| CN208399240U (en) * | 2018-05-14 | 2019-01-18 | 柳州市妇幼保健院 | A kind of aobvious tape drum of chromosome N |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110907256A (en) * | 2019-12-19 | 2020-03-24 | 广州达安临床检验中心有限公司 | Chromosome N banding method |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |