CN108684665A - 3,3 ', 5,5 '-tetrabromobisphenol of compound, 2 '-'-biphenyl diphenols are in algal control and except the application of algae aspect - Google Patents

3,3 ', 5,5 '-tetrabromobisphenol of compound, 2 '-'-biphenyl diphenols are in algal control and except the application of algae aspect Download PDF

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Publication number
CN108684665A
CN108684665A CN201810456283.9A CN201810456283A CN108684665A CN 108684665 A CN108684665 A CN 108684665A CN 201810456283 A CN201810456283 A CN 201810456283A CN 108684665 A CN108684665 A CN 108684665A
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algae
algal control
application
reagent
compound
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CN201810456283.9A
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CN108684665B (en
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张永雨
解瑞泽
李德海
孙春晓
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Qingdao Institute of Bioenergy and Bioprocess Technology of CAS
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Qingdao Institute of Bioenergy and Bioprocess Technology of CAS
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F1/00—Treatment of water, waste water, or sewage
    • C02F1/50—Treatment of water, waste water, or sewage by addition or application of a germicide or by oligodynamic treatment
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F2103/00—Nature of the water, waste water, sewage or sludge to be treated
    • C02F2103/20—Nature of the water, waste water, sewage or sludge to be treated from animal husbandry
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F2303/00—Specific treatment goals
    • C02F2303/04—Disinfection

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Water Supply & Treatment (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Hydrology & Water Resources (AREA)
  • Environmental & Geological Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention discloses 3,3 ', 5,5 '-tetrabromobisphenol of compound, application of the 2 '-'-biphenyl diphenols in terms of algal control.The present invention by kill algae spectrum experiments have shown that, the compound all has good effect of algae restraint for 11 kinds of algae such as pseudo- short hailian seaweed, Chaetoceros muelleri, prorocentrum minimum, Amphidinium carterae, micro- quasi- ball algae, prochlorococcus, Dunaliella salina, Phaeodactylum tricornutum, chlorella, marine green alga, purple ball algaes, for administering the natural calamities such as red tide, wawter bloom, prevents body eutrophication and be of great significance.

Description

3,3 ', 5,5 '-tetrabromobisphenol of compound, 2 '-'-biphenyl diphenols are in algal control and except algae aspect Using
Technical field
The present invention relates to the new opplication fields of compound, and in particular to 3,3 ', 5,5 '-tetrabromobisphenol of compound, 2 '-biphenyl two Phenol is in algal control and except the application of algae aspect.
Background technology
" red tide ", be otherwise known as " red ghost ", is a kind of abnormal phenomenon in marine ecosystems.With human society Industrialization degree aggravates, and the effluent sewage for largely containing various itrogenous organic substances is discharged into seawater, is promoted seawater eutrophication, is promoted Red tide algae mass propagation.Under the action of various factors, the red tide algae in seaweed family is broken out under certain environmental conditions Caused by being proliferated to property, red tide is caused.As a kind of harmful natural phenomena, the harm that red tide is brought is also very huge:
1. a large amount of red tide planktons are collected in the gill portion of fish, make fish death by suffocation due to anoxic.
2. after red tide plankton death, frond largely consumes the dissolved oxygen in water in decomposable process, lead to fish and other Marine organisms can also release a large amount of pernicious gases and toxin because of hypoxia death, and serious pollution of marine environment makes ocean The normal ecosystem is by serious destruction.
A large amount of toxic algaes 3. fish eat.
Water pollution is set to cause fish dead 4. some algae can secrete noxious material.
After red tide occurs, in addition to seawater becomes red, while the pH value of seawater can also increase, and viscosity increases, non-red tide The planktonic organism of algae can dead, decaying;Red tide algae also mortality due to burst proliferation, excessively aggregation.In the whole world There is more than 260 kinds can form red tide in more than 4000 kinds of marine phytoplankton, wherein there is more than 70 kinds can generate toxin.Its toxin secreted has Marine organisms mortality can be directly resulted in a bit, some can even be transmitted by food chain, and human foods is caused to be poisoned.
In freshwater system, there is also similar natural hazard, it is referred to as " wawter bloom ".Measures of Algae in Water Body mass propagation, water Body starts to be in blue, green or crineous.Enter water body mainly due to the effluent sewage containing a large amount of nitrogen, phosphorus in life and industrial and agricultural production Afterwards, algal bloom becomes the dominant population in water body, and " wawter bloom " phenomenon just occurs therewith.The appearance of this phenomenon can make It will also be seriously threatened at the mortality of existence fish in water body and the safety of drinking water.
Algae-lysing bacterium is the general designation of a kind of bacterium for inhibiting algal grown in a manner of direct or indirect or cracking frustule, In to secrete based on the indirect mode of extracellular anti-algal substance;Micro anti-algal substance can suppress algal grown or cracking algae is thin Born of the same parents." controlling algae by bacterium " is in a manner of a kind of red tide control with important foreground, however at present for the research of anti-algal substance, also Large stretch of blank.Therefore, exploitation is about the product with alga-inhibiting action, the improvement for red tide, wawter bloom, maintains the flat of the ecosystem Scale is significant.
Invention content
The present invention for red tide, wawter bloom etc. natural calamities prevention, pass through research find compound 3,3 ', 5,5 '-four Bromo- 2, new opplication of the 2 '-'-biphenyl diphenols as anti-algal substance all has good suppression for a variety of algae in nature water body Effect processed.
In order to realize that the above technical purpose, the present invention propose following technical scheme:
It is an object of the present invention to provide 3,3 ', 5,5 '-tetrabromobisphenols of compound, and 2 '-'-biphenyl diphenols are in terms of algal control Using.
The compound structure is as shown below:
By killing algae spectrum it is demonstrated experimentally that 3,3 ', 5,5 '-tetrabromobisphenol of compound, 2 '-'-biphenyl diphenols deposit a variety of algal growns In inhibiting effect, to the strong alga-inhibiting action of part algae reality, algal control rate reaches 75% or more.
The second purpose of the present invention is to provide a kind of algal control reagent, which is compound 3,3 ', 5,5 '-four Bromo- 2, the preparation solution of 2 '-'-biphenyl diphenols, wherein further including other bacterial extracts with alga-inhibiting action.
Preferably, above-mentioned 3,3 ', 5,5 '-tetrabromobisphenols, 2 '-'-biphenyl diphenols prepare a concentration of 10 μ g/mL of solution.
The three of the object of the invention are to provide a kind of algal control kit, which is characterized in that trying comprising above-mentioned algal control Agent.
The four of the object of the invention are to provide a kind of algal control method, i.e., mentioned reagent is added into algae solution.
Preferably, above-mentioned algal control reagent is added in 5% ratio in algae solution.
Preferably, the condition of culture of above-mentioned algae solution is 20 DEG C, intensity of illumination 3000lx, light dark period 12h of temperature:12h.
Preferably, the algae that above-mentioned algal control method is directed to is pseudo- short hailian seaweed, Chaetoceros muelleri, prorocentrum minimum, strong Anterior canal algae, micro- quasi- ball algae, prochlorococcus, Dunaliella salina, Phaeodactylum tricornutum, chlorella, marine green alga, purple ball algae.
Further, green for pseudo- short hailian seaweed, Chaetoceros muelleri, prorocentrum minimum, Amphidinium carterae, micro- quasi- ball algae, original Ball algae, Dunaliella salina.
The five of the object of the invention are that provide above-mentioned algal control reagent is administering red tide, wawter bloom with algal control kit and method, Prevent the application of fish pond eutrophication etc..
Beneficial effects of the present invention
3,3 ', 5,5 '-tetrabromobisphenol of compound, 2 '-'-biphenyl diphenols are mostly used to make the intermediate of chemical industry synthesis in the prior art, The research being applied in current research is less.The research of the present invention is found that a kind of completely new application of the compound, for The further exploitation of compound is made that contribution.
Description of the drawings
The accompanying drawings which form a part of this application are used for providing further understanding of the present application, and the application's shows Meaning property embodiment and its explanation do not constitute the improper restriction to the application for explaining the application.
Fig. 1 is 3,3 ', 5,5 '-tetrabromobisphenol of various dose, effect of algae restraint figure of the 2 '-'-biphenyl diphenols to Synechococcus PCC7002;
Wherein, compound 3,3 ', 5,5 '-tetrabromobisphenols, 2 '-'-biphenyl diphenol solution be added algae solution in action time be five days.
Specific implementation mode
It is noted that following detailed description is all illustrative, it is intended to provide further instruction to the application.Unless another It indicates, all technical and scientific terms used herein has usual with the application person of an ordinary skill in the technical field The identical meanings of understanding.
It should be noted that term used herein above is merely to describe specific implementation mode, and be not intended to restricted root According to the illustrative embodiments of the application.As used herein, unless the context clearly indicates otherwise, otherwise singulative It is also intended to include plural form, additionally, it should be understood that, when in the present specification using term "comprising" and/or " packet Include " when, indicate existing characteristics, step, operation, device, component and/or combination thereof.
The present invention a kind of specific implementation mode be to provide compound 3,3 ', 5,5 '-tetrabromobisphenol, 2 '-'-biphenyl diphenols exist Application in terms of algal control.By killing algae spectrum it is demonstrated experimentally that 3,3 ', 5,5 '-tetrabromobisphenol of compound, 2 '-'-biphenyl diphenols are to a variety of algaes There are inhibiting effect for class growth, there is strong alga-inhibiting action, algal control rate to reach 75% or more part algae.
In another specific implementation mode of the present invention, a kind of algal control reagent is provided, which is compound 3,3 ', 5, 5 '-tetrabromobisphenols, the preparation solution of 2 '-'-biphenyl diphenols and other algal control bacterial extracts.
In preferred embodiment, a concentration of 10 μ g/mL of above-mentioned preparation solution.
In another specific implementation mode of the present invention, a kind of algal control kit is provided, which is characterized in that wrapping Containing above-mentioned algal control reagent.
In another specific implementation mode of the present invention, a kind of algal control method is provided, i.e., mentioned reagent is added into algae solution.
In preferred embodiment, above-mentioned algal control reagent is added in 5% ratio in algae solution.
In preferred embodiment, the condition of culture of above-mentioned algae solution is 20 DEG C, intensity of illumination 3000lx of temperature, light dark period 12h:12h。
In preferred embodiment, the algae that above-mentioned algal control method is directed to is pseudo- short hailian seaweed, Chaetoceros muelleri, small original Dinoflagellate, Amphidinium carterae, micro- quasi- ball algae, prochlorococcus, Dunaliella salina, Phaeodactylum tricornutum, chlorella, marine green alga, purple Ball algae.
In the embodiment advanced optimized, for pseudo- short hailian seaweed, Chaetoceros muelleri, prorocentrum minimum, Amphidinium carterae, Micro- quasi- ball algae, prochlorococcus, Dunaliella salina.
In another specific implementation mode of the present invention, above-mentioned algal control reagent is provided and is being controlled with algal control kit and method Red tide, wawter bloom are managed, the application in terms of fish pond eutrophication is prevented.
1 algistatic activity computational methods of embodiment
1. tested algae and condition of culture
It is tested algae to select Synechococcus PCC7002, and in 26 DEG C, intensity of illumination 3000lx, light dark period 12h of temperature: It is cultivated under the conditions of 12h, then culture to exponential phase is dispensed into 50mL triangular flasks, every bottle of packing 20mL algae solution.
2. algal control rate calculates
It takes the component 1mL to be measured of 10 μ g/mL to be added in above-mentioned Synechococcus PCC7002 algae solutions, cultivates 5 days, then glimmering It is counted under light microscope.
Algal control rate calculates as follows
Algal control rate (Algicidal rate)=(NC-NT)/NC× 100%
NCIndicate the viable count in control group, NTIndicate the viable count in experimental group.
Algal control rate is considered as more than 75% strong alga-inhibiting action, and being considered as between 50%~75% has effect of algae restraint, is less than 50% It is considered as no effect of algae restraint.
The algal control range of 2 compound of embodiment
Select pseudo- short hailian seaweed, Chaetoceros muelleri, prorocentrum minimum, Amphidinium carterae, micro- quasi- ball algae, prochlorococcus, salt Raw Du Shi algaes, Phaeodactylum tricornutum, chlorella, marine green alga, purple ball 3,3 ', 5,5 '-tetrabromobisphenol of algae pair, 2 '-'-biphenyl diphenols into Row kills algae spectrum experiment.Condition of culture is:20 DEG C, intensity of illumination 3000lx, light dark period 12h of temperature:12h.The 3 of 10 μ g/mL are taken, 3 ', 5,5 '-tetrabromobisphenols, 2 '-'-biphenyl diphenols are added in 5% ratio in above-mentioned 11 kinds of algae solutions, and by the algal control in embodiment 1 Rate calculation formula calculates algal control rate.
Experimental result shows 3,3 ', 5,5 '-tetrabromobisphenols, and 2 '-'-biphenyl diphenols are to pseudo- short hailian seaweed, Chaetoceros muelleri, small Prorocentrum micans, Amphidinium carterae, micro- quasi- ball algae, prochlorococcus, Dunaliella salina show strong alga-inhibiting action (algal control Shuai > 75%) alga-inhibiting action (algal control rate 50~75%), is shown to Phaeodactylum tricornutum, chlorella, marine green alga, purple ball algae.Knot Fruit is as shown in the table:
The foregoing is merely the preferred embodiments of the application, are not intended to limit this application, for the skill of this field For art personnel, the application can have various modifications and variations.Within the spirit and principles of this application, any made by repair Change, equivalent replacement, improvement etc., should be included within the protection domain of the application.

Claims (10)

1. 3,3 ', 5,5 '-tetrabromobisphenol of compound, application of the 2 '-'-biphenyl diphenols in terms of algal control.
2. application as described in claim 1, which is characterized in that the algae is pseudo- short hailian seaweed, Chaetoceros muelleri, small original Dinoflagellate, Amphidinium carterae, micro- quasi- ball algae, prochlorococcus, Dunaliella salina, Phaeodactylum tricornutum, chlorella, marine green alga, purple Ball algae;Preferably, be pseudo- short hailian seaweed, Chaetoceros muelleri, prorocentrum minimum, Amphidinium carterae, micro- quasi- ball algae, prochlorococcus, Dunaliella salina.
3. a kind of algal control reagent, which is characterized in that the reagent is 3,3 ', 5,5 '-tetrabromobisphenols, and the preparation of 2 '-'-biphenyl diphenols is molten Liquid further includes other algal control bacterial extracts;Preferably, 3,3 ', 5,5 '-tetrabromobisphenols in the reagent, 2 '-'-biphenyl diphenols it is dense Degree is 10 μ g/mL.
4. a kind of algal control kit, which is characterized in that the algal control kit includes reagent described in claim 3.
5. a kind of algal control method, which is characterized in that reagent described in claim 3 is added into algae solution.
6. method as claimed in claim 5, which is characterized in that the reagent is added in 5% ratio in algae solution.
7. method as claimed in claim 5, which is characterized in that the algae solution condition of culture is:20 DEG C of temperature, intensity of illumination 3000lx, light dark period 12h:12h.
8. method as claimed in claim 5, which is characterized in that the algae is pseudo- short hailian seaweed, Chaetoceros muelleri, small original Dinoflagellate, Amphidinium carterae, micro- quasi- ball algae, prochlorococcus, Dunaliella salina, Phaeodactylum tricornutum, chlorella, marine green alga, purple Ball algae;Preferably, be pseudo- short hailian seaweed, Chaetoceros muelleri, prorocentrum minimum, Amphidinium carterae, micro- quasi- ball algae, prochlorococcus, Dunaliella salina.
9. algal control kit described in algal control reagent as claimed in claim 3, claim 4 is administering red tide, wawter bloom, prevent fish pond The application of body eutrophication.
10. the method described in claim 5-8 is administering red tide, wawter bloom, is preventing the application in terms of fish pond eutrophication.
CN201810456283.9A 2018-05-14 2018-05-14 Application of compound 3,3 ', 5,5 ' -tetrabromo-2, 2 ' -biphenol in inhibiting and removing algae Active CN108684665B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2346001A1 (en) * 1975-03-11 1977-10-28 Dick Pierre Pharmaceutical compsn. contg. tetra:halo di:phenol - for treatment of fasciola hepatica and fasciola gigantica in mammals
US20090163692A1 (en) * 2007-12-21 2009-06-25 General Electric Company Aromatic polyethers

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2346001A1 (en) * 1975-03-11 1977-10-28 Dick Pierre Pharmaceutical compsn. contg. tetra:halo di:phenol - for treatment of fasciola hepatica and fasciola gigantica in mammals
US20090163692A1 (en) * 2007-12-21 2009-06-25 General Electric Company Aromatic polyethers

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