CN108680623A - A kind of portable electrochemical determining fingerprint pattern instrument - Google Patents
A kind of portable electrochemical determining fingerprint pattern instrument Download PDFInfo
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- CN108680623A CN108680623A CN201811027818.7A CN201811027818A CN108680623A CN 108680623 A CN108680623 A CN 108680623A CN 201811027818 A CN201811027818 A CN 201811027818A CN 108680623 A CN108680623 A CN 108680623A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
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Abstract
The invention belongs to instrument analysis technology fields, specially a kind of portable electrochemical determining fingerprint pattern instrument, including pretreating device, integrated reformer and signal pickup assembly, the input terminal of the integrated reformer is connected with the pretreating device, the signal pickup assembly is connected on the integrated reformer, the pretreating device includes grinding device and device for storing liquid, and the grinding device and device for storing liquid are respectively positioned on the input terminal of the integrated reformer；Integrated reformer is equipped with agitating device, attemperator and atmosphere protection device, and reactor is realized stirring, kept the temperature, the function of atmosphere protection, three substitution constant temperature system, magnetic stirring apparatus, reactor components；And data are obtained by Sensitive Detector, signal acquisition module and signal processing module；It is equipped with grinding device and device for storing liquid in pretreating device, material is simply anticipated, the use of tool is saved, is convenient for carrying, is conducive to field operation.
Description
Technical field
The invention belongs to instrument analysis technology fields, and in particular to a kind of portable electrochemical determining fingerprint pattern instrument.
Background technology
Electrochemistry finger-print：I.e. in BrO3-—Mn2+—H+In-acetone oscillation system, each substance in oscillation system is adjusted
Concentration, Chinese medicine participate in electrochemical oscillation reaction and as oscillation dissipation substrate, the characteristic oscillation waveform of acquisition, keep vibrate
Under conditions of each material concentration of system is constant, only change the type of Chinese medicine, obtainable difference Chinese medicine characteristic oscillation waveform is different
Chinese medicine is because the chemical analysis that contains is different, and with the totally different electrochemistry finger-print of shape, Chinese medicine of the same race, ingredient is identical
But relative amount is different, and electrochemistry finger-print shape is similar, but characteristic parameter is different, and electrochemistry finger-print has fingerprint
Property, specificity and characteristic.
The Chinese patent of Publication No. CN101995422B proposes a kind of scheme：A kind of nonlinear chemical fingerprint point
Analyzer is based on nonlinear chemical fingerprint analysis method, in scheme：Computer, instrument, reactor, electrode, constant temperature system,
Magnetic stirring apparatus waits multi-parts to connect, and uses, occupies bigger, for some in-site measurements in fixed laboratory, hence it is evident that
Be inconvenient to move, for the substance measured, there is liquid phase, need to be quantitatively adding, needs to carry corresponding liquid shifting equipment；For
Solid matter（Such as Chinese medicine）, it needs to crush, it is dry, it is measured after weighing, pre-treatment is also required to some task equipments, and field measuring is not
It is convenient, in detection process, which directly contacts with air, also surveyed without the operation except oxygen in preceding processing
Potential error is easy tod produce when some fixed active stronger raw materials, influences measurement accuracy.
Invention content
The purpose of the present invention is to provide a kind of portable electrochemical determining fingerprint pattern instrument, to solve above-mentioned background technology
In be proposed for some in-site measurements, hence it is evident that be inconvenient to move, pre-treatment is also required to some task equipments, field measuring not side
Just, also without the operation except oxygen in preceding processing, the problem of influencing measurement accuracy.
To achieve the above object, the present invention provides the following technical solutions：A kind of portable electrochemical determining fingerprint pattern instrument,
Including pretreating device, integrated reformer and signal pickup assembly, the input terminal of the integrated reformer is connected with described
Pretreating device, the signal pickup assembly is connected on the integrated reformer, and the pretreating device includes crushing to fill
It sets and device for storing liquid, the grinding device and device for storing liquid are respectively positioned on the input terminal of the integrated reformer, the integrated form
Reactor includes stirring box, agitating device, attemperator and atmosphere protection device, and the stirring box is internally provided with stirring dress
It sets, the attemperator is located at the inner wall of the stirring box, is additionally provided with atmosphere protection device in the stirring box, the signal is adopted
Acquisition means include Sensitive Detector, signal acquisition module and signal processing module, and the Sensitive Detector stretches to the stirring
The inside of box, the Sensitive Detector are connect with the signal acquisition module input terminal, the output end of the signal acquisition module
It is connected with the signal processing module.
Preferably, the grinding device includes crush box, sawtooth roller, crank, miniature title, pallet, inlet port and outlet port,
The side of the crush box is fixed with the miniature title, and the miniature side of being much of is equipped with the pallet, the crush box it is interior
Portion is rotatably connected to the sawtooth roller, is sequentially connected with the crank on the outside of the sawtooth roller, and up and down the two of the crush box
End is respectively equipped with the feed inlet and the discharge port, and the discharge port is connected to the input terminal of the stirring box.
Preferably, the device for storing liquid includes the first buffering liquid storage ball, the second buffering liquid storage ball, fixed plate, ingress pipe, degree
The bottom of buret and switch valve, the first buffering liquid storage ball and the second buffering liquid storage ball is respectively connected with ingress pipe, and described solid
Fixed board is fixed on the outer wall of two ingress pipes, and the ingress pipe is described in and extends to the inside, and described first is slow
The measurement that is fixedly arranged above for rushing liquid storage ball and the second buffering liquid storage ball is managed, and is set there are three measurement pipe on the first buffering liquid storage ball,
It is connected by switch valve between the measurement pipe and the first buffering liquid storage ball and the second buffering liquid storage ball.
Preferably, the agitating device includes stirring motor, connecting shaft and agitating paddle, and the stirring motor is fixed on described
The upper cover middle position of box is stirred, the output end of the stirring motor is connected with the connecting shaft, the stirring motor and institute
Agitating paddle is stated to be sequentially connected by the connecting shaft.
Preferably, the attemperator includes temperature sensor, temperature controller and heater, the temperature sensor position
In the bottom of the stirring box, and the inside of the stirring box is extended to, the temperature sensor is connected to the temperature control
The input terminal of device, the heater are located at the inner wall of the stirring box, and the heater is connected to the defeated of the temperature controller
Outlet.
Preferably, the atmosphere protection device include gas tube and breather cheek valve and be mounted on the stirring box head cover
On unidirectional air outlet valve, the gas tube is connected to the input terminal of the breather cheek valve, and the breather cheek valve is located at described
The inside of box is stirred, the gas tube has the interface of Pagoda-shaped.
Preferably, the outer wall of the inner wall smooth of the crush box, the sawtooth roller slidably connects cleaning brush, the cleaning
Brush is fixed on the inner wall of the crush box, and the crush box is equipped with clean-out door close to the outside of the sawtooth roller.
Preferably, the Sensitive Detector includes working electrode and reference electrode, and the working electrode and the reference are electric
Pole is each attached to the head cover of the stirring box and extends to the inside of the stirring box, and the working electrode and reference electrode pass through
A/D circuits are connected in the signal acquisition module.
Preferably, thermal insulation layer is equipped between the stirring box and the heater, the thermal insulation layer is by heat insulation foam and stone
Cotton forms.
Compared with prior art, the beneficial effects of the invention are as follows：Integrated reformer be equipped with agitating device, attemperator and
Atmosphere protection device, make reactor realize stirring, heat preservation, atmosphere protection function, substitution constant temperature system, magnetic stirring apparatus,
Three components of reactor；And data are obtained by Sensitive Detector, signal acquisition module and signal processing module, mainly sometimes
Between ~ relational graph of current potential；In pretreating device be equipped with grinding device and device for storing liquid, can experiment carry out before, to material into
Row is simply anticipated, and is saved the use of tool, is convenient for carrying, and field operation is conducive to.
Description of the drawings
Fig. 1 is the structural diagram of the present invention；
Fig. 2 is the crush box structural schematic diagram of the present invention；
Fig. 3 is the device for storing liquid structural schematic diagram of the present invention；
Fig. 4 is the structure composition block diagram of the present invention；
Fig. 5 is the structure composition block diagram of the present invention；
Fig. 6 is 2 attached drawing of the embodiment of the present invention；
Fig. 7 is 3 attached drawing of the embodiment of the present invention；
In figure：1, pretreating device；11, grinding device；111, crush box；112, sawtooth roller；113, crank；114, miniature title；
115, pallet；116, feed inlet；117, discharge port；12, device for storing liquid；121, the first buffering liquid storage ball；122, the second buffering storage
Liquid ball；123, fixed plate；124, ingress pipe；125, measurement pipe；126, switch valve；2, integrated reformer；21, agitating device；
201, box is stirred；211, stirring motor；212, connecting shaft；213, agitating paddle；22, attemperator；221, temperature sensor；222、
Temperature controller；223, heater；23, atmosphere protection device；231, gas tube；232, breather cheek valve；3, signal acquisition fills
It sets；31, Sensitive Detector；311, working electrode；312, reference electrode；32, signal acquisition module；33, signal processing module.
Specific implementation mode
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation describes, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
Embodiment 1：
- 5 are please referred to Fig.1, the present invention provides a kind of technical solution：A kind of portable electrochemical determining fingerprint pattern instrument, including it is preceding
Processing unit 1, integrated reformer 2 and signal pickup assembly 3, the input terminal of integrated reformer 2 are connected with pretreating device
1, signal pickup assembly 3 is connected on integrated reformer 2, pretreating device 1 includes grinding device 11 and device for storing liquid 12, powder
Crushing device 11 and device for storing liquid 12 are respectively positioned on the input terminal of integrated reformer 2, and integrated reformer 2 includes stirring box 201, stirs
Device 21, attemperator 22 and atmosphere protection device 23 are mixed, stirring box 201 is internally provided with agitating device 21, attemperator 22
It positioned at the inner wall of stirring box 201, stirs and is additionally provided with atmosphere protection device 23 in box 201, signal pickup assembly 3 includes sensing detection
Device 31, signal acquisition module 32 and signal processing module 33, Sensitive Detector 31 stretch to the inside of stirring box 201, sensing inspection
It surveys device 31 to connect with 32 input terminal of signal acquisition module, the output end of signal acquisition module 32 is connected with signal processing module 33.
In the present embodiment, Sensitive Detector 31 stretches to the inside of stirring box 201, Sensitive Detector 31 and signal acquisition mould
32 input terminal of block connects, and the output end of signal acquisition module 32 is connected with signal processing module 33, and Sensitive Detector 31 is for examining
Survey the electrode potential signal during nonlinear chemical reaction；Signal acquisition module 32 is used for acquisition electrode electric potential signal, signal
Processing module 33 generates nonlinear chemical fingerprint according to electrode potential signal, and carries out atlas analysis, obtains analysis result.
Further, grinding device 11 include crush box 111, sawtooth roller 112, crank 113, miniature title 114, pallet 115,
The side of feed inlet 116 and discharge port 117, crush box 111 is fixed with miniature title 114, and the top of miniature title 114 is equipped with pallet
115, the inner rotation of crush box 111 is connected with sawtooth roller 112, and the outside of sawtooth roller 112 is sequentially connected with crank 113, crushes
The upper and lower ends of case 111 are respectively equipped with feed inlet 116 and discharge port 117, and discharge port 117 is connected to the input terminal of stirring box 201.
In the present embodiment, grinding device 11 includes crush box 111, sawtooth roller 112, crank 113, miniature title 114, pallet
115, the side of feed inlet 116 and discharge port 117, crush box 111 is fixed with miniature title 114, and the top of miniature title 114 is equipped with support
Disk 115 can weigh a certain amount of Chinese medicinal material that experiment needs by miniature title 114 and pallet 115, reduce medicinal material and handling
When, it needs separately experiment equipment to be taken to be weighed on testing stand, the inner rotation of crush box 111 is connected with sawtooth roller 112, sawtooth
The outside of roller 112 is sequentially connected with crank 113, drives the gear in gear-box to engage by crank 113, drives two sawtooth rollers
112 rotations, crush Chinese medicinal material, more preferably realize that effect, the upper and lower ends of crush box 111 are respectively equipped with to realize
Feed inlet 116 and discharge port 117, discharge port 117 are connected to the input terminal of stirring box 201, can be by the Chinese medicinal material after crushing
It is sent in stirring box 201 by discharge port 117.
Further, device for storing liquid 12 include the first buffering liquid storage ball 121, second buffer liquid storage ball 122, fixed plate 123,
The bottom of ingress pipe 124, measurement pipe 125 and switch valve 126, the first buffering liquid storage ball 121 and the second buffering liquid storage ball 122 connects
It is connected to ingress pipe 124, and fixed plate 123 is fixed on the outer wall of two ingress pipes 124, ingress pipe 124 is through 201 and extends to
Inside 201, the first buffering liquid storage ball 121 and being fixedly arranged above for the second buffering liquid storage ball 122 measure pipe 125, optimal, and first
It buffers connection on liquid storage ball 121 and buffers liquid storage ball 121 and the second buffering storage there are three pipe 125, measurement pipe 125 and first is measured
It is connected by switch valve 126 between liquid ball 122.
In the present embodiment, device for storing liquid 12 includes that the first buffering liquid storage ball 121, second buffers liquid storage ball 122, fixed plate
123, ingress pipe 124, measurement pipe 125 and switch valve 126, the bottom of the first buffering liquid storage ball 121 and the second buffering liquid storage ball 122
It is respectively connected with ingress pipe 124, and fixed plate 123 is fixed on the outer wall of two ingress pipes 124, device for storing liquid 12 is set as synchronous
Two, can liquid be imported according to step in operation, ingress pipe 124 is through 201 and extends to inside 201, first
Buffering liquid storage ball 121 and being fixedly arranged above for the second buffering liquid storage ball 122 measure pipe 125, optimal, the first buffering liquid storage ball
Connection can be used for importing sulfuric acid, acetone and the sulfuric acid acid manganese mixed liquor being added at one time, degree there are three pipe 125 is measured on 121
Buret 125 and first buffers to be connected by switch valve 126 between liquid storage ball 121 and the second buffering liquid storage ball 122, facilitates control
The importing of liquid processed.
Further, agitating device 21 includes stirring motor 211, connecting shaft 212 and agitating paddle 213, and stirring motor 211 is solid
It is scheduled on the upper cover middle position of stirring box 201, the output end of stirring motor 211 is connected with connecting shaft 212, stirring motor 211
It is sequentially connected by connecting shaft 212 with agitating paddle 213.
In the present embodiment, agitating device 21 includes stirring motor 211, connecting shaft 212 and agitating paddle 213, stirring motor 211
It is fixed on the upper cover middle position of stirring box 201, the output end of stirring motor 211 is connected with connecting shaft 212, stirring motor
211 and agitating paddle 213 be sequentially connected by connecting shaft 212, stirring motor 211 can be with according to the temperature feedback in stirring box 201
Different rotating speeds is set, to ensure during the reaction, can be controlled agitating paddle 213 by different rotating speeds and reach suitable
Stirring extent makes reaction reach more preferably effect.
Further, attemperator 22 includes temperature sensor 221, temperature controller 222 and heater 223, and temperature passes
Sensor 221 is located at the bottom of stirring box 201, and extends to the inside of stirring box 201, and temperature sensor 221 is connected to temperature control
The input terminal of device 222 processed, heater 223 are located at the inner wall of stirring box 201, and heater 223 is connected to the defeated of temperature controller 222
Outlet.
In the present embodiment, attemperator 22 includes temperature sensor 221, temperature controller 222 and heater 223, temperature
Sensor 221 is located at the bottom of stirring box 201, and extends to the inside of stirring box 201, is stirred by the detection of temperature sensor 221
The temperature of 201 internal-response liquid of box is mixed, and with electric signal transmission to temperature controller 222, temperature sensor 221 is connected to temperature
The input terminal of controller 222, heater 223 are located at the inner wall of stirring box 201, and heater 223 is connected to temperature controller 222
Output end when detecting that temperature is high, then stops the heating of heater 223 by the advance setting value of temperature controller 222,
When the temperature is low, then the heating for improving heater 223 makes the temperature of reaction solution reach suitable temperature.
Further, atmosphere protection device 23 is including gas tube 231 and breather cheek valve 232 and mounted on stirring box
Unidirectional air outlet valve on 201 head covers, gas tube 231 are connected to the input terminal of breather cheek valve 232, and breather cheek valve 232 is located at
The inside of box 201 is stirred, gas tube 231 has the interface of Pagoda-shaped.
In the present embodiment, atmosphere protection device 23 is including gas tube 231 and breather cheek valve 232 and mounted on stirring box
Unidirectional air outlet valve on 201 head covers, gas tube 231 are connected to the input terminal of breather cheek valve 232, pass through gas tube 231 and list
Cooperation to intake valve 232, may be implemented, and before experiment carries out, indifferent gas is poured into stirring box 201 by gas tube 231
Body, and will not be leaked by the guarantee of breather cheek valve 232, and when air pressure is high, gas can be by stirring on 201 head cover of box
Unidirectional air outlet valve discharge, ensure discharge stirring box 201 in oxygen, prevent oxygen reaction when participate in reaction, one-way air inlet
Valve 232 is located at the inside of stirring box 201, and gas tube 231 has the interface of Pagoda-shaped, when ensureing inflation, what gas tube 231 connected
Reliability.
Further, the outer wall of the inner wall smooth of crush box 111, sawtooth roller 112 slidably connects cleaning brush, and cleaning brush is solid
It is scheduled on the inner wall of crush box 111, and crush box 111 is equipped with clean-out door close to the outside of sawtooth roller 112.
In the present embodiment, the inner wall smooth of crush box 111 reduces the herb powder that 111 inner wall of crush box is detained, sawtooth roller
112 outer wall slidably connects cleaning brush, and cleaning brush is fixed on the inner wall of crush box 111, to the remaining powder on sawtooth roller 112
End is cleaned, and reduces hold-up of the powder on sawtooth roller 112, and crush box 111 is equipped with clearly close to the outside of sawtooth roller 112
Door is swept, can be opened the clean-out door in 112 outside of sawtooth roller if necessary, be cleaned manually.
Further, Sensitive Detector 31 includes working electrode 311 and reference electrode 312, and working electrode 311 and reference are electric
Pole 312 is each attached to the head cover of stirring box 201 and extends to the inside of stirring box 201, working electrode 311 and reference electrode 312
It is connected in signal acquisition module 32 by A/D circuits.
In the present embodiment, Sensitive Detector 31 includes working electrode 311 and reference electrode 312, working electrode 311 and reference
Electrode 312 is each attached to the head cover of stirring box 201 and extends to the inside of stirring box 201, working electrode 311 and reference electrode
312 are connected to by A/D circuits in signal acquisition module 32, and working electrode 311 and reference electrode 312 are detected box 201 is stirred
To signal be connected in signal acquisition module 32 by A/D acquisition modules and by amplifying circuit, pass through signal processing module
Data import unit, collection of illustrative plates processing unit, parameter in 33 are asked and calculate unit, quantitative analysis unit carries out analysis calculating, and will knot
Fruit exports.
Further, it stirs and is equipped with thermal insulation layer between box 201 and heater 223, thermal insulation layer is by heat insulation foam and asbestos group
At.
In the present embodiment, stirs and be equipped with thermal insulation layer between box 201 and heater 223, thermal insulation layer is by heat insulation foam and asbestos
Composition, can increase the thermal energy input efficiency of heater 223, reduce the loss of heat.
The operation principle and process for using of the present invention：It is 300 r/ in 211 rotating speed of stirring motor after the present invention installs
Under the magnetic agitation of min, 37 DEG C of reaction temperature is controlled by temperature controller 222, before experiment carries out, passes through gas tube
231 pour nitrogen into stirring box 201 and continue five minutes, and will not be leaked by the guarantee of breather cheek valve 232, and gas
When pressing high, gas can be discharged by the unidirectional air outlet valve stirred on 201 head cover of box, ensure the oxygen in discharge stirring box 201,
It prevents oxygen from participating in reaction in reaction, is separately added into 1.0000 g Milkvetch Roots, after instrument grinding device 11 directly crushes, into
Enter into stirring box 201, by being separately added into three measurement pipes 125 of the device for storing liquid 12 on the first buffering liquid storage ball 121
Manganese sulfate solution 5mL and 1mol/L the sulfuric acid solution 10ml of acetone soln 5mL, 0.04mol/L of 0.4mol/L are slow second
Rush the bromic acid potassium solution 10mL that 0.2mol/L is added in the measurement pipe 125 of the top of liquid storage ball 122, and by switch valve 126 by third
Ketone solution, manganese sulfate solution and sulfuric acid solution are imported into stirring box 201, open signal harvester 3, after 10min, open the
The switch valve 126 of two buffering liquid storage balls, 122 top, is rapidly added the bromic acid potassium solution 10mL of 0.2mol/L, immediately begins to record
Data, measure response voltage and time graph to oscillating reactions terminates, that is, obtain electrochemistry finger-print, as shown in Figure 5.
Referring to Fig. 6, the present invention provides a kind of technical solution：After the present invention installs, it is in 211 rotating speed of stirring motor
Under the magnetic agitation of 300 r/min, 37 DEG C of reaction temperature is controlled by temperature controller 222, before experiment carries out, multiple
Helium is poured into stirring box 201 by gas tube 231 respectively in experiment（Neon, argon gas）And continue five minutes, and pass through list
It will not be leaked to the guarantee of intake valve 232, and when air pressure is high, gas can pass through the unidirectional outlet stirred on 201 head cover of box
Valve is discharged, and ensures the oxygen in discharge stirring box 201, prevents oxygen from participating in reaction in reaction, is separately added into 1.0000 g Huangs
Stilbene medicinal material after instrument grinding device 11 directly crushes, enters in stirring box 201, is stored up in the first buffering by device for storing liquid 12
The manganese sulfate of acetone soln 5mL, 0.04mol/L for being separately added into 0.4mol/L in three measurement pipes 125 on liquid ball 121 are molten
Liquid 5mL and 1mol/L sulfuric acid solution 10ml is added 0.2mol/L's in the measurement pipe 125 above the second buffering liquid storage ball 122
Bromic acid potassium solution 10mL, and acetone soln, manganese sulfate solution and sulfuric acid solution are imported by stirring box 201 by switch valve 126
In, open signal harvester 3 after 10min, is opened the switch valve 126 of 122 top of the second buffering liquid storage ball, is rapidly added
The bromic acid potassium solution 10mL of 0.2mol/L immediately begins to record data, measures response voltage and time graph to oscillating reactions knot
Beam obtains electrochemistry finger-print, obtain data such as Fig. 6, it can be deduced that, obtaining seven characteristics includes（Induction time shakes
Swing service life, peak swing, cycle of oscillation, maximum potential, potential minimum, equilibrium potential）RSD be respectively 3.62%, 4.22%,
4.89%, 4.25%, 0.225%, 3.45%, 1.61%, it can be seen that its relative standard's standard deviation is respectively less than 5%, it was demonstrated that obtains
There is Radix Astragali finger-print good reproducibility, collection of illustrative plates to meet the requirement that traditional Chinese medicine fingerprint must satisfy.
Referring to Fig. 7, the present invention provides a kind of technical solution：After the present invention installs, it is in 211 rotating speed of stirring motor
Under the magnetic agitation of 300 r/min, 37 DEG C of reaction temperature is controlled by temperature controller 222, before experiment carries out, by filling
Tracheae 231 pours nitrogen into stirring box 201 and continues five minutes, and will not be leaked by the guarantee of breather cheek valve 232,
And air pressure it is high when, gas can by stir 201 head cover of box on unidirectional air outlet valve be discharged, ensure discharge stirring box 201 in
Oxygen prevents oxygen from participating in reaction in reaction, 1.0000 g Rabdosia rubescens medicinal materials is separately added into many experiments（RADIX PAEONIAE ALBA
Material）, after instrument grinding device 11 directly crushes, enter in stirring box 201, liquid storage ball buffered first by device for storing liquid 12
The manganese sulfate solution 5mL of acetone soln 5mL, 0.04mol/L of 0.4mol/L are separately added into three measurement pipes 125 on 121
With 1mol/L sulfuric acid solution 10ml, the bromic acid of 0.2mol/L is added in the measurement pipe 125 above the second buffering liquid storage ball 122
Potassium solution 10mL, and acetone soln, manganese sulfate solution and sulfuric acid solution are imported into stirring box 201 by switch valve 126, it opens
It opens signal pickup assembly 3, after 10min, opens the switch valve 126 of 122 top of the second buffering liquid storage ball, be rapidly added 0.2mol/L
Bromic acid potassium solution 10mL, immediately begin to record data, measure response voltage and time graph to oscillating reactions and terminate, while can
To find out the similarity of Rabdosia rubescens and Radix Paeoniae Alba and Radix Astragali all 90% hereinafter, illustrate that Radix Astragali has unique finger-print, therefore,
It can be used for identifying the true and false of Radix Astragali.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
Understanding without departing from the principles and spirit of the present invention can carry out these embodiments a variety of variations, modification, replace
And modification, the scope of the present invention is defined by the appended.
Claims (9)
1. a kind of portable electrochemical determining fingerprint pattern instrument, it is characterised in that：Including pretreating device（1）, integrated form reaction
Device（2）And signal pickup assembly（3）, the integrated reformer（2）Input terminal be connected with the pretreating device（1）, institute
State integrated reformer（2）On be connected with the signal pickup assembly（3）, the pretreating device（1）Including grinding device
（11）And device for storing liquid（12）, the grinding device（11）And device for storing liquid（12）It is respectively positioned on the integrated reformer（2）'s
Input terminal, the integrated reformer（2）Including stirring box（201）, agitating device（21）, attemperator（22）And atmosphere protection
Device（23）, the stirring box（201）Be internally provided with agitating device（21）, the attemperator（22）Positioned at the stirring box
（201）Inner wall, the stirring box（201）Inside it is additionally provided with atmosphere protection device（23）, the signal pickup assembly（3）Including passing
Feel detector（31）, signal acquisition module（32）And signal processing module（33）, the Sensitive Detector（31）It stretches to described
Stir box（201）Inside, the Sensitive Detector（31）With the signal acquisition module（32）Input terminal connects, the signal
Acquisition module（32）Output end be connected with the signal processing module（33）.
2. a kind of portable electrochemical determining fingerprint pattern instrument according to claim 1, it is characterised in that：The crushing dress
It sets（11）Including crush box（111）, sawtooth roller（112）, crank（113）, miniature title（114）, pallet（115）, feed inlet（116）
And discharge port（117）, the crush box（111）Side be fixed with the miniature title（114）, the miniature title（114）It is upper
Side is equipped with the pallet（115）, the crush box（111）Inner rotation be connected with the sawtooth roller（112）, the sawtooth roller
（112）Outside be sequentially connected with the crank（113）, the crush box（111）Upper and lower ends be respectively equipped with the charging
Mouthful（116）With the discharge port（117）, the discharge port（117）It is connected to the stirring box（201）Input terminal.
3. a kind of portable electrochemical determining fingerprint pattern instrument according to claim 1, it is characterised in that：The liquid storage dress
It sets（12）Including the first buffering liquid storage ball（121）, second buffering liquid storage ball（122）, fixed plate（123）, ingress pipe（124）, degree
Buret（125）And switch valve（126）, the first buffering liquid storage ball（121）With the second buffering liquid storage ball（122）Bottom connect
It is connected to ingress pipe（124）, and the fixed plate（123）It is fixed on two ingress pipes（124）Outer wall, the ingress pipe
（124）Through described（201）And it extends to described（201）Inside, the first buffering liquid storage ball（121）With the second buffering liquid storage
Ball（122）Be fixedly arranged above measurement pipe（125）, the measurement pipe（125）With the first buffering liquid storage ball（121）And the
Two buffering liquid storage balls（122）Between pass through switch valve（126）Connection.
4. a kind of portable electrochemical determining fingerprint pattern instrument according to claim 1, it is characterised in that：The stirring dress
It sets（21）Including stirring motor（211）, connecting shaft（212）And agitating paddle（213）, the stirring motor（211）It is fixed on described
Stir box（201）Upper cover middle position, the stirring motor（211）Output end be connected with the connecting shaft（212）, institute
State stirring motor（211）With the agitating paddle（213）Pass through the connecting shaft（212）It is sequentially connected.
5. a kind of portable electrochemical determining fingerprint pattern instrument according to claim 1, it is characterised in that：The heat preservation dress
It sets（22）Including temperature sensor（221）, temperature controller（222）And heater（223）, the temperature sensor（221）Position
In the stirring box（201）Bottom, and extend to the stirring box（201）Inside, the temperature sensor（221）Connection
In the temperature controller（222）Input terminal, the heater（223）Positioned at the stirring box（201）Inner wall, it is described plus
Hot device（223）It is connected to the temperature controller（222）Output end.
6. a kind of portable electrochemical determining fingerprint pattern instrument according to claim 1, it is characterised in that：The atmosphere is protected
Protection unit（23）Including gas tube（231）And breather cheek valve（232）And it is mounted on the stirring box（201）List on head cover
To air outlet valve, the gas tube（231）It is connected to the breather cheek valve（232）Input terminal, the breather cheek valve（232）
Positioned at the stirring box（201）Inside, the gas tube（231）Interface with Pagoda-shaped.
7. a kind of portable electrochemical determining fingerprint pattern instrument according to claim 2, it is characterised in that：The crush box
（111）Inner wall smooth, the sawtooth roller（112）Outer wall slidably connect cleaning brush, the cleaning brush is fixed on the powder
Broken case（111）Inner wall, and the crush box（111）Close to the sawtooth roller（112）Outside be equipped with clean-out door.
8. a kind of portable electrochemical determining fingerprint pattern instrument according to claim 1, it is characterised in that：The sensing inspection
Survey device（31）Including working electrode（311）And reference electrode（312）, the working electrode（311）With the reference electrode（312）
It is each attached to the stirring box（201）Head cover and extend to the stirring box（201）Inside, the working electrode（311）
And reference electrode（312）It is connected to the signal acquisition module by A/D circuits（32）On.
9. a kind of portable electrochemical determining fingerprint pattern instrument according to claim 5, it is characterised in that：The stirring box
（201）With the heater（223）Between be equipped with thermal insulation layer, the thermal insulation layer is made of heat insulation foam and asbestos.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811027818.7A CN108680623B (en) | 2018-09-05 | 2018-09-05 | Portable electrochemical fingerprint spectrum tester |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811027818.7A CN108680623B (en) | 2018-09-05 | 2018-09-05 | Portable electrochemical fingerprint spectrum tester |
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| CN108680623A true CN108680623A (en) | 2018-10-19 |
| CN108680623B CN108680623B (en) | 2020-06-30 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201811027818.7A Active CN108680623B (en) | 2018-09-05 | 2018-09-05 | Portable electrochemical fingerprint spectrum tester |
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| CN111579621A (en) * | 2020-05-27 | 2020-08-25 | 四川国康药业有限公司 | Method for detecting astragalus membranaceus tablets by chemical oscillation fingerprint spectrum |
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| CN108680623B (en) | 2020-06-30 |
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