CN108680503A - Liquid controls chip and system - Google Patents

Liquid controls chip and system Download PDF

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Publication number
CN108680503A
CN108680503A CN201810477733.2A CN201810477733A CN108680503A CN 108680503 A CN108680503 A CN 108680503A CN 201810477733 A CN201810477733 A CN 201810477733A CN 108680503 A CN108680503 A CN 108680503A
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liquid
layer
hole
communication portion
imaging
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王闯
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Individual
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Solid State Image Pick-Up Elements (AREA)

Abstract

The present invention relates to a kind of liquid control chip and systems.It includes the hyaline layer stacked gradually, imaging layer, electrode layer and supporting layer that liquid, which controls chip,.Hyaline layer is equipped with liquid-entering hole.Liquid control chip is additionally provided with suction hole, and suction hole is used to flow through the air in access for liquid in air-extractor pumping liquid control chip.Liquid communication portion is additionally provided between liquid-entering hole and suction hole.The one end in liquid communication portion is connected to liquid-entering hole, and the other end in liquid communication portion is connected to suction hole.The imaging area being made of hyaline layer and imaging layer is equipped in liquid communication portion.Imaging layer in imaging area is for receiving incident ray, with the corresponding image of the liquid for being formed with flowing through imaging area.After blood is flowed into from liquid-entering hole in liquid control chip, control terminal can analyze the ingredient of blood by the image extracted in imaging area, and realization method is simple, to improve the convenience of blood analysis.

Description

Liquid controls chip and system
Technical field
The present invention relates to technical field of liquid detection, and chip and system are controlled more particularly to a kind of liquid.
Background technology
Blood testing is technology more important in medical domain.Blood includes the cell of three kinds of different function:It is red thin Born of the same parents, leucocyte and blood platelet.By observing quantity variation and the fractions distribution of each cell, the common of the diagnosis state of an illness can be used as One of auxiliary examination methods.Therefore, how to provide it is a kind of convenient for analysis blood chip be always the problem of people more pay close attention to.
Invention content
Based on this, it is necessary to for how to provide a kind of the problem of being convenient for analyzing the chip of blood, provide a kind of liquid control Coremaking piece and system.
A kind of liquid control chip, is controlled by control terminal;Liquid control chip include the hyaline layer stacked gradually, at As layer, electrode layer and supporting layer;
The hyaline layer is equipped with liquid-entering hole;The liquid control chip is additionally provided with suction hole, and the suction hole is used for Liquid in liquid control chip, which is aspirated, for air-extractor flows through air in access;
Liquid communication portion is additionally provided between the liquid-entering hole and the suction hole;The one end in the liquid communication portion and institute Liquid-entering hole connection is stated, and the other end in the liquid communication portion is connected to the suction hole;In the liquid communication portion be equipped with by The imaging area that the hyaline layer is constituted with the imaging layer;The imaging layer in the imaging area is for receiving incident light Line, with the corresponding image of the liquid for being formed with flowing through the imaging area.
In one of the embodiments, the liquid communication portion include the first passage being sequentially communicated, it is filter hole, second logical Road, through-hole and third channel;
The first passage is also connected to the liquid-entering hole, and the first passage is arranged in the imaging layer and the electricity Pole layer, and on the supporting layer;The filter hole is located on the supporting layer;The second channel is located at the supporting layer It is interior;The through-hole is located on the supporting layer, and is arranged in the electrode layer;The third channel is located on the electrode layer, And the imaging area is located in the third channel.
The liquid communication portion further includes the first electrode pair set on the through-hole both ends in one of the embodiments,; The two pairs of electrodes of the first electrode pair are located in the second channel, in the third channel;
The first electrode pair flows through the telecommunications that the through-hole generates for connecting the control terminal, and for detecting liquid Number.
The liquid communication portion further includes being set between the imaging area and the suction hole in one of the embodiments, First electrode unit;The first electrode unit is used to send the second telecommunications to the control terminal after touching the liquid Number, stop aspirating the liquid control so that the control terminal controls the air-extractor after receiving second electric signal Air in coremaking piece.
The liquid communication portion further includes being set to the imaging area and the first electrode list in one of the embodiments, Second electrode unit between member;The second electrode unit is used to send the to the control terminal when touching the liquid Three electric signals are accordingly run so that the control terminal controls the air-extractor after receiving the third electric signal.
The liquid communication portion further includes being set to the first electrode unit and the suction in one of the embodiments, Termination hole between hole and fourth lane, and the termination hole is connected to the fourth lane;
The termination hole is arranged in the electrode layer, and is also connected to the third channel;The fourth lane is located at Below the electrode layer, and also it is connected to the suction hole.
The supporting layer includes the first substrate layer and the second substrate layer in one of the embodiments,;Wherein, described first Substrate layer is between the electrode layer and second substrate layer.
In one of the embodiments, the thickness of the imaging layer between 0.04mm between 0.15mm.
The aperture of the through-hole is between 0.03mm to 0.08mm in one of the embodiments,.
A kind of liquid control system, including control terminal and liquid control chip;The control terminal is for controlling the liquid Control chip operation;The liquid control chip includes the hyaline layer stacked gradually, imaging layer, electrode layer and supporting layer;
The hyaline layer is equipped with liquid-entering hole;The liquid control chip is additionally provided with suction hole, and the suction hole is used for Liquid in liquid control chip, which is aspirated, for air-extractor flows through air in access;
Liquid communication portion is additionally provided between the liquid-entering hole and the suction hole;The one end in the liquid communication portion and institute Liquid-entering hole connection is stated, and the other end in the liquid communication portion is connected to the suction hole;In the liquid communication portion be equipped with by The imaging area that the hyaline layer is constituted with the imaging layer;The imaging layer in the imaging area is for receiving incident light Line, with the corresponding image of the liquid for being formed with flowing through the imaging area.
Aforesaid liquid control chip and system have the advantage that for:The liquid controls in chip, and blood is by entering liquid Hole enters liquid communication portion, and when blood can form corresponding image behind imaging area so that control terminal being capable of basis The image analyzes blood.Therefore, when blood from liquid-entering hole flow into the liquid control chip in after, control terminal by As area extract image the ingredient of blood can be analyzed, realization method is simple, to improve the convenient of blood analysis Property.
Description of the drawings
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below There is attached drawing needed in technology description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this Some embodiments of invention for those of ordinary skill in the art without creative efforts, can be with The attached drawing of other embodiment is obtained according to these attached drawings.
Fig. 1 is the structural schematic diagram for the hyaline layer that the liquid that an embodiment provides controls chip;
Fig. 2 is the structural schematic diagram that the liquid of Fig. 1 illustrated embodiments controls the imaging layer of chip;
Fig. 3 is the positive structure schematic that the liquid of Fig. 1 illustrated embodiments controls the electrode layer of chip;
Fig. 4 is the reverse structure schematic that the liquid of Fig. 1 illustrated embodiments controls the electrode layer of chip;
Fig. 5 is the structural schematic diagram that the liquid of Fig. 1 illustrated embodiments controls the supporting layer of chip.
Specific implementation mode
To facilitate the understanding of the present invention, below with reference to relevant drawings to invention is more fully described.In attached drawing Give presently preferred embodiments of the present invention.But the present invention can realize in many different forms, however it is not limited to this paper institutes The embodiment of description.Keep the understanding to the disclosure more thorough on the contrary, purpose of providing these embodiments is Comprehensively.
Unless otherwise defined, the skill of all of technologies and scientific terms used here by the article and the technical field for belonging to invention The normally understood meaning of art personnel is identical.Description to be intended merely in the term used in the description of invention specific herein The purpose of embodiment, it is not intended that the limitation present invention.Term as used herein "and/or" includes one or more relevant institutes Any and all combinations of list of items.
One embodiment provides a kind of liquid control chip, is controlled by control terminal.Wherein, liquid control chip can be right Blood or other liquid are detected, such as can detect the quantity of blood middle leukocytes.Control terminal is, for example, computer, and is controlled End processed and liquid control chip can transmission datas in a wireless or wired way.
It please refers to Fig.1 to Fig. 5, it includes the hyaline layer 10, imaging layer 20, electrode layer 30 stacked gradually which, which controls chip, And supporting layer 40.Wherein, hyaline layer 10 can be made with light transmission, such as hyaline layer 10 of glass.Imaging layer 20 is used to form It can reflect that the image of fluid characteristics, such as imaging layer 20 can be made of photosensitive material.Specifically, the color of imaging layer 20 can Think black.Specifically, the thickness of imaging layer 20 between 0.04mm between 0.15mm.Electrode layer 30 is used for transmission electric signal, Such as electrode layer 30 is made of an electrically conducting material.Supporting layer 40 plays a supportive role.
Referring to FIG. 1, in present embodiment, hyaline layer 10 is equipped with liquid-entering hole 100.Wherein, liquid-entering hole 100 is used for liquid Body imports in liquid control chip.It please refers to Fig.1 to Fig. 5, liquid control chip is additionally provided with suction hole 200, and suction hole 200 for liquid in air-extractor pumping liquid control chip for flowing through the air in access.Wherein, air-extractor is for example, true Sky pump.Air-extractor can be controlled by control terminal.Under the control of control terminal, air-extractor passes through 200 pumping liquid of suction hole The air in chip is controlled, so that liquid is controlled by 100 influent of liquid-entering hole in chip under the action of negative pressure, and Flow through corresponding access.Wherein, suction hole 200 can be arranged in hyaline layer 10, imaging layer 20, electrode layer 30 successively, as long as protecting Card air-extractor by suction hole 200 can pumping liquid liquid control chip in flow through access in air.
In addition, being additionally provided with liquid communication portion between liquid-entering hole 100 and suction hole 200.Liquid can in liquid communication portion With flowing.The one end in liquid communication portion is connected to liquid-entering hole 100, and the other end in liquid communication portion is connected to suction hole 200.Cause This, liquid is after the inflow of liquid-entering hole 100, you can is flowed in liquid communication portion.Meanwhile referring to FIG. 2, liquid communication portion It is interior to be equipped with the imaging area 310 being made of hyaline layer 10 and imaging layer 20.Imaging layer 20 in imaging area 310 for receive into Light is penetrated, with the corresponding image of the liquid for being formed with flowing through imaging area 310.
Wherein, after liquid enters imaging area 310, liquid is then between hyaline layer 10 and imaging layer 20.When liquid flows through When imaging area 310, ambient will expose to the imaging layer 20 in imaging area 310 by liquid.Therefore, if imaging layer 20 by Photosensitive material is made, then when liquid flows through imaging area 310, if external light source emits light to imaging area 310, light passes through Liquid exposes to imaging layer 20, imaging layer 20 can occur corresponding with liquid chemical reaction (such as:Due to blocking for leucocyte So that the corresponding imaging layer of leucocyte 20 will not chemically react in liquid, and do not have in liquid the position of impurity it is corresponding at As layer 20 then occurs normally to chemically react), so as to form image corresponding with liquid.Control terminal is by extracting imaging area 310 images formed, you can liquid is analyzed, such as:When liquid is blood, control terminal can calculate white thin in blood The quantity of born of the same parents.
In conclusion present embodiment provide aforesaid liquid control chip in, it is assumed that liquid is blood, then when blood from After liquid-entering hole 100 flows into liquid control chip, control terminal can be to the ingredient of blood by the image extracted in imaging area 310 It is analyzed, realization method is simple, to improve the convenience of blood analysis.
Supporting layer 40 includes the first substrate layer and the second substrate layer in one of the embodiments,.Wherein, the first substrate layer Between electrode layer 30 and the second substrate layer.Material identical of first substrate layer for example with imaging layer 20.Second substrate layer example Such as with the material identical of hyaline layer 10.Also, suction hole 200 can be through the first substrate layer, and is located on the second substrate layer.
In the present embodiment, supporting layer 40 is constituted using two-layer substrate, so as to improve the reliability of support.It is appreciated that , the constituted mode of supporting layer 40 is not limited to a kind of above-mentioned situation, such as supporting layer 40 can also use a kind of material to constitute.
It is please referred to Fig.1 in one of the embodiments, to Fig. 5, liquid communication portion includes the first passage being sequentially communicated 320, filter hole 330, second channel 340, through-hole 350 and third channel 360.Therefore, liquid enters the liquid from liquid-entering hole 100 After controlling chip, first passage 320, filter hole 330, second channel 340, through-hole 350 and third channel 360 will be passed through successively.
Wherein, first passage 320 is also connected to liquid-entering hole 100, and first passage 320 is arranged in imaging layer 20, electrode layer 30, and on supporting layer 40.Therefore, the top of first passage 320 is hyaline layer 10, and bottom is supporting layer 40.
Filter hole 330 is located on supporting layer 40.Specifically, filter hole 330 for example includes the several holes arranged by array, from And the impurity that volume is larger in liquid can be filtered out.Second channel 340 is located in supporting layer 30.Therefore, filter hole 330 can be with The liquid flowed out from first passage 320 is filtered, and filtered liquid is made to flow into second channel 340.
Through-hole 350 is located on supporting layer 40, and is arranged in electrode layer 30.Third channel 360 is located on electrode layer 30, and at As area 310 is located in third channel 360.Therefore, by the way that through-hole 350 is arranged, the liquid flowed through in supporting layer 40 can be imported To electrode layer 30, so that liquid can be by imaging area 310.
Wherein, through-hole 350 can also control the flow velocity of liquid, so that liquid flows into third channel with suitable flow velocity In 360, to meet the needs of obtaining electric signal.Since third channel 360 is located on electrode layer 30, third channel is flowed through 360 liquid will touch electrode layer 30, to generate corresponding electric signal, and liquid can also by imaging area 310, with Form corresponding image.Specifically, the aperture of through-hole 350 is between 0.03mm to 0.08mm.
Specifically, in the case where supporting layer 40 includes above-mentioned first substrate layer and the second substrate layer, filter hole 330 can be with Be arranged in the first substrate layer, second channel 340 can be arranged in the first substrate layer, and on the second substrate layer, through-hole 350 according to It is secondary to be arranged in the first substrate layer, electrode layer 30.In this way, the liquid flowed out from first passage 320 enters after filter hole 330 In second channel 340, at this point, the top contact electrode layer 30 of liquid, the bottom of liquid contacts the second substrate layer.Later, liquid It will be flowed into third channel 360 by through-hole 350.
Specifically, in third channel 360 other than 310 corresponding position of imaging area, other positions can be arranged in into As layer 20 and on electrode layer 30, and imaging area 310 is then made of hyaline layer 10 and imaging layer 20.Therefore, when liquid flows into After third channel 360, when being flowed in other positions other than imaging area 310, the top of liquid will touch transparent Layer 10, bottom will touch electrode layer 20, once and liquid flow into imaging area 310, then the top of liquid will touch The bottom of bright layer 10, liquid will touch imaging layer 20.
Further, it please refers to Fig.3, Fig. 4, liquid communication portion further includes the first electrode pair set on 350 both ends of through-hole 371.The two pairs of electrodes of first electrode pair 371 are located at second channel 340, third channel 360.
First electrode pair 371 is for connecting control terminal, and the electric signal for detecting the generation of liquid flow via through holes 350.Cause This, after liquid flows through second channel 340, since the top of liquid can contact electrode layer 20, so as to touch first First plate electrode of electrode pair 371, when liquid flows through third channel 360, since the bottom of liquid can touch electrode layer 20, to can equally touch another plate electrode in first electrode pair 371.
To sum up, in the present embodiment, when the particle (such as leucocyte) in liquid passes through through-hole 350, since particle is logical Instead of the liquid of same volume in hole 350, cause the resistance between 350 two end electrodes of through-hole that transient change has occurred, to Corresponding voltage pulse signal can be generated.After control terminal receives voltage pulse signal, by counting voltage pulse signal The image that number and integrated imaging area 310 obtain, you can determine correlated characteristic of particle in liquid, such as volume, number etc., from And the accuracy of fluid analysis can be improved.
Further, referring to FIG. 3, liquid communication portion further includes first be set between imaging area 310 and suction hole 200 Electrode unit 372.First electrode unit 372 is used to send the second electric signal to control terminal after touching liquid, so that control End processed controls the air in air-extractor stopping pumping liquid control chip after receiving the second electric signal.Specifically, first Electrode unit 372 is located on electrode layer 30.
Therefore, after liquid flows through first electrode unit 372, first electrode unit 372 can be in time by the second of detection Electric signal is sent to control terminal, so that can effectively to control air-extractor out of service for control terminal, is flowed out to avoid liquid.
Further, with continued reference to FIG. 3, liquid communication portion further includes being set to imaging area 310 and first electrode unit 372 Between second electrode unit 373.Second electrode unit 373 is used to send third telecommunications to control terminal when touching liquid Number, it is accordingly run so that control terminal controls air-extractor after receiving third electric signal.Specifically, second electrode unit 373 are located on electrode layer 30.
Wherein, control terminal is, for example, according to the specific implementation that third electric signal control air-extractor is accordingly run:Control System termination receives third electric signal, can control air-extractor and carry out the preparation for stopping suction air, to flow to first in liquid After electrode unit 372 so that air-extractor can be rapid out of service, avoids liquid from flowing out the liquid control to further increase The reliability of coremaking piece;Alternatively, after control terminal receives third electric signal, can control air-extractor reduces pumping speed, to subtract The speed of small liquid flowing.
It is understood that the specific set-up mode in liquid communication portion is not limited to the above situation, such as:According to practical feelings Condition, if only needing to can guarantee that air-extractor can stop aspirating air in time by first electrode unit 372, without setting Second electrode unit 373.
Further, it please refers to Fig.3 to Fig. 5, liquid communication portion further includes being set to first electrode unit 372 and suction hole Termination hole 380 between 200 and fourth lane 390.Also, it terminates hole 380 to be connected to fourth lane 390
Wherein, it terminates hole 380 and is arranged in electrode layer 30, and be also connected to third channel 360.In the present embodiment, terminate Hole 380 is between third channel 360 and fourth lane 390.Fourth lane 390 is located at the lower section of electrode layer 30, and also with pumping Sucker 200 is connected to.Wherein, fourth lane 390 for example can be between electrode layer 30 and supporting layer 40, or is located at supporting layer In 40 (such as:Fourth lane 390 is arranged in the first substrate layer, and on the second substrate layer).
Therefore, in the present embodiment, by the way that fourth lane 390 is arranged, it can prevent liquid trickle from controlling chip, to carry The reliability of high liquid control chip.
Next by taking Fig. 1 to liquid shown in fig. 5 controls the one of which specific implementation of chip as an example, its work is introduced Make principle:Control terminal controls air-extractor and passes through the air in 200 pumping liquid of suction hole control chip.Under the action of negative pressure, Liquid will enter first passage 320 by liquid-entering hole 100.When liquid is after filter hole 330, impurity can be filtered.It crosses Liquid after filter passes through second channel 340, cocurrent via through holes 350.At this point, since liquid passes through first electrode pair 371, the One electrode pair 371 will will produce corresponding electric signal (such as voltage pulse signal), and the electric signal is sent to control terminal.It Afterwards, liquid flowing in the third channel 360, when liquid is behind imaging area 310, if extraneous light is incident to imaging area 310, position Imaging layer 20 in imaging area 310 will form image corresponding with liquid, and control terminal obtains the image, you can in conjunction with above-mentioned Electric signal analyzes liquid with the image synthesis.At the same time, liquid continues to flow in third channel 360, when by second electrode When unit 373, second electrode unit 373 sends third electric signal to control terminal, is controlled after control terminal receives third electric signal Air-extractor processed carries out the preparation before stopping pumping.After liquid continues to flow and reach first electrode unit 372, first Electrode unit 372 sends the second electric signal to control terminal, after control terminal receives the second electric signal, then controls air-extractor stopping Pumping, liquid will stop flowing at this time.
Another embodiment provides a kind of liquid control system, including control terminal and liquid control chip;The control End is for controlling the liquid control chip operation.The liquid control chip includes the hyaline layer, imaging layer, electricity stacked gradually Pole layer and supporting layer.The hyaline layer is equipped with liquid-entering hole.The liquid control chip is additionally provided with suction hole, and the suction hole Air in access is flowed through for aspirating liquid in liquid control chip for air-extractor.
Liquid communication portion is additionally provided between the liquid-entering hole and the suction hole.The one end in the liquid communication portion and institute Liquid-entering hole connection is stated, and the other end in the liquid communication portion is connected to the suction hole.In the liquid communication portion be equipped with by The imaging area that the hyaline layer is constituted with the imaging layer.The imaging layer in the imaging area is for receiving incident light Line, with the corresponding image of the liquid for being formed with flowing through the imaging area.
It should be noted that control terminal, liquid control chip difference in the liquid control system that present embodiment provides Corresponding control terminal, the liquid control operation principle of chip with the above embodiment is identical, just repeats no more here.
Each technical characteristic of embodiment described above can be combined arbitrarily, to keep description succinct, not to above-mentioned reality It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited In contradiction, it is all considered to be the range of this specification record.
Several embodiments of the invention above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the protection of the present invention Range.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.

Claims (10)

1. a kind of liquid controls chip, controlled by control terminal;It is characterized in that, the liquid control chip includes stacking gradually Hyaline layer, imaging layer, electrode layer and supporting layer;
The hyaline layer is equipped with liquid-entering hole;The liquid control chip is additionally provided with suction hole, and the suction hole is used for for taking out Gas equipment aspirates liquid in liquid control chip and flows through air in access;
Liquid communication portion is additionally provided between the liquid-entering hole and the suction hole;The one end in the liquid communication portion with it is described enter Fluid apertures is connected to, and the other end in the liquid communication portion is connected to the suction hole;It is equipped with by described in the liquid communication portion The imaging area that hyaline layer is constituted with the imaging layer;The imaging layer in the imaging area is used to receive incident ray, With the corresponding image of the liquid for being formed with flowing through the imaging area.
2. liquid according to claim 1 controls chip, which is characterized in that the liquid communication portion includes being sequentially communicated First passage, filter hole, second channel, through-hole and third channel;
The first passage is also connected to the liquid-entering hole, and the first passage is arranged in the imaging layer and the electrode Layer, and on the supporting layer;The filter hole is located on the supporting layer;The second channel is located at the supporting layer It is interior;The through-hole is located on the supporting layer, and is arranged in the electrode layer;The third channel is located on the electrode layer, And the imaging area is located in the third channel.
3. liquid according to claim 2 controls chip, which is characterized in that the liquid communication portion further includes set on described The first electrode pair at through-hole both ends;The two pairs of electrodes of the first electrode pair are located in the second channel, the third In channel;
The first electrode pair flows through the electric signal that the through-hole generates for connecting the control terminal, and for detecting liquid.
4. liquid according to claim 2 controls chip, which is characterized in that the liquid communication portion further includes set on described First electrode unit between imaging area and the suction hole;The first electrode unit be used for after touching the liquid to The control terminal sends the second electric signal, so that the control terminal controls the pumping after receiving second electric signal Equipment stops aspirating the air in the liquid control chip.
5. liquid according to claim 4 controls chip, which is characterized in that the liquid communication portion further includes set on described Second electrode unit between imaging area and the first electrode unit;The second electrode unit is for touching the liquid Third electric signal is sent to the control terminal when body, so that the control terminal controls institute after receiving the third electric signal Air-extractor is stated accordingly to run.
6. liquid according to claim 4 controls chip, which is characterized in that the liquid communication portion further includes set on described Termination hole between first electrode unit and the suction hole and fourth lane, and the termination hole connects with the fourth lane It is logical;
The termination hole is arranged in the electrode layer, and is also connected to the third channel;The fourth lane is located at described Below electrode layer, and also it is connected to the suction hole.
7. the liquid according to any one of claim 1 to 6 claim controls chip, which is characterized in that the support Layer includes the first substrate layer and the second substrate layer;Wherein, first substrate layer is located at the electrode layer and second substrate Between layer.
8. the liquid according to any one of claim 1 to 6 claim controls chip, which is characterized in that the imaging The thickness of layer is between 0.04mm between 0.15mm.
9. the liquid according to any one of claim 2 to 6 claim controls chip, which is characterized in that the through-hole Aperture between 0.03mm to 0.08mm.
10. a kind of liquid control system, including control terminal and liquid control chip;The control terminal is for controlling the liquid control Coremaking piece is run;It is characterized in that, the liquid control chip includes the hyaline layer stacked gradually, imaging layer, electrode layer and branch Support layer;
The hyaline layer is equipped with liquid-entering hole;The liquid control chip is additionally provided with suction hole, and the suction hole is used for for taking out Gas equipment aspirates liquid in liquid control chip and flows through air in access;
Liquid communication portion is additionally provided between the liquid-entering hole and the suction hole;The one end in the liquid communication portion with it is described enter Fluid apertures is connected to, and the other end in the liquid communication portion is connected to the suction hole;It is equipped with by described in the liquid communication portion The imaging area that hyaline layer is constituted with the imaging layer;The imaging layer in the imaging area is used to receive incident ray, With the corresponding image of the liquid for being formed with flowing through the imaging area.
CN201810477733.2A 2018-05-18 2018-05-18 Liquid controls chip and system Pending CN108680503A (en)

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Application Number Priority Date Filing Date Title
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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103175950A (en) * 2011-12-20 2013-06-26 中国科学院深圳先进技术研究院 Hemocyte analysis chip and system for using chip thereof
CN103471981A (en) * 2013-08-30 2013-12-25 大连海事大学 High-throughput grain counting device and method based on micro-fluidic chip
CN204116189U (en) * 2014-03-13 2015-01-21 严媚 The imaging of intelligent optical miniflow and detection system
CN107213930A (en) * 2017-07-27 2017-09-29 深圳中科芯海智能科技有限公司 A kind of micro-fluidic chip and particle analysis method for particle analysis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103175950A (en) * 2011-12-20 2013-06-26 中国科学院深圳先进技术研究院 Hemocyte analysis chip and system for using chip thereof
CN103471981A (en) * 2013-08-30 2013-12-25 大连海事大学 High-throughput grain counting device and method based on micro-fluidic chip
CN204116189U (en) * 2014-03-13 2015-01-21 严媚 The imaging of intelligent optical miniflow and detection system
CN107213930A (en) * 2017-07-27 2017-09-29 深圳中科芯海智能科技有限公司 A kind of micro-fluidic chip and particle analysis method for particle analysis

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Application publication date: 20181019