CN108671416B - A kind of medical laser thermotherapy target head based on graphite-based composite heat conducting material - Google Patents

A kind of medical laser thermotherapy target head based on graphite-based composite heat conducting material Download PDF

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CN108671416B
CN108671416B CN201810530615.3A CN201810530615A CN108671416B CN 108671416 B CN108671416 B CN 108671416B CN 201810530615 A CN201810530615 A CN 201810530615A CN 108671416 B CN108671416 B CN 108671416B
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graphite
target head
conducting material
heat conducting
thermal conductive
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CN108671416A (en
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李静
雷汝白
黄邹琴
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South China University of Technology SCUT
Zhuhai Institute of Modern Industrial Innovation of South China University of Technology
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Zhuhai Institute of Modern Industrial Innovation of South China University of Technology
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    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0625—Warming the body, e.g. hyperthermia treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/067—Radiation therapy using light using laser light
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    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/515—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxide ceramics
    • C04B35/52—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxide ceramics based on carbon, e.g. graphite
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    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
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    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2235/00—Aspects relating to ceramic starting mixtures or sintered ceramic products
    • C04B2235/70—Aspects relating to sintered or melt-casted ceramic products
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    • C04B2235/9607—Thermal properties, e.g. thermal expansion coefficient

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Abstract

The medical laser thermotherapy target head based on graphite-based composite heat conducting material that the invention discloses a kind of；Including protection overcoat, internal insulation, thermal conductive belt and outer heat insulation layer；Protection overcoat front end is equipped with end, and rear end is equipped with connector, and the side and connector rear end center of connector are respectively equipped with opening, and two openings are connected to by channel, and the opening at optic fibre linker rear end center is protruded into, entered at the side mouth of end；Internal insulation is wrapped in the optical fiber periphery of connector rear end, thermally conductive to have multilayer, and Spaced is arranged in internal insulation periphery, each layer of thermally conductive spaced setting；Outer heat insulation layer is wrapped in thermal conductive belt periphery；Thermal conductive belt is made of a plurality of long arc shape sheet；Thermal conductive belt is made of graphite base heat conducting material；It solves the problems, such as the flexible of burning problems as caused by heat deposition in target head use process and target head, is conducive to the power for improving medical laser thermotherapy target head, reduces target head quality and reduce target head quality.

Description

A kind of medical laser thermotherapy target head based on graphite-based composite heat conducting material
Technical field
The present invention relates to a kind of laserthermia target heads, more particularly to a kind of based on the medical of graphite-based composite heat conducting material Laserthermia target head belongs to medical thermotherapy instrument field.
Background technique
Thermotherapy is to kill cancer cell in the way of external heat source heating tumor tissues, while not damaging normal tissue cells, It is applied in accurate tumor thermotherapy as operative treatment, chemotherapy, radiotherapy and the supplement of biological therapy.Due to swashing Light has high brightness, the characteristics such as directionality and monochromaticjty, so that its good heat source for becoming thermotherapy is led to using optical fiber laser It crosses and the optical fiber equipped with laser head is inserted into tumor tissues in need for the treatment of, guidance laser irradiation corresponds to tissue heat production and reaches accurate Therapeutic effect.Existing laser therapeutic head often by way of water cooling, such as uses rigid all-metal water cooling target head, the metal water-cooling Target head is due to needing fluid conveying machine, thus target head volume is big, is unfavorable for reducing wound wound area；And water cooling is micro- logical Road processing difficulties, the capacity of heat transmission is limited, leads to the easy scaling loss of optical fiber head, the easy adhesion between tissue；Rigid all-metal water cooled target simultaneously For head due to being rigid structure, the flexibility that target head uses is poor, it is difficult to the big blood vessel of human body or vitals are avoided in use, Operative risk is big.
Summary of the invention
In view of the deficiency of the prior art, the present invention provides a kind of heat-conducting effects to continue well, light weight, body Product is small, with good flexibility, it can reduce wound wound area to avoid tissue of burn and avoid the big blood vessel of human body or important device The medical laser thermotherapy target head based on graphite-based composite heat conducting material of official.
Graphite is a kind of raw mineral materials being widely present in nature, there are unformed shape (crystallite), flakey crystal and Three kinds of highly crystalline state.Flake graphite be carbon atom composition hexagonal reticular structure overlapping body, formed the carbon atom of hexagonal ring with sp2The σ key that hybridized orbit electronically forms is connected with the pi bond that orbital electron is formed, C-C bond distance 0.142nm, average bond energy 627kJ/mol, hexgonal net interlayer are combined with Van der Waals force, and interlamellar spacing is about 0.335nm, are had and thermal conductivity similar in metal Rate, and since graphite layers are without chemical bond composition, longitudinal thermal conductivity between layers becomes the main of limitation graphite thermal conductivity Factor.Traditional Heat Conduction Material is based on metal, and thermal coefficient is hundred grades of W/ (mk), using graphite-based as the NEW TYPE OF COMPOSITE of representative Material, has multiple use in engineering field, and the thermal coefficient of relevant report has thousand grades of W/ (mk) or more.Single layer or few layer Graphite-based material made of graphene is constructed has excellent heating conduction, but since thermal reduction graphene oxide process generates gas Body causes piece lamellar spacing to become larger, and influences the heating conduction duration of graphite-based material；The content of present invention is with existing graphite material Basis fills up modification intralayer defects by adding filler, obtains light weight, low-cost, has lasting height preferably flexible Heating conduction graphite-base composite material.
In order to achieve the above object, the present invention adopts the following technical scheme:
A kind of medical laser thermotherapy target head based on graphite-based composite heat conducting material, including protection overcoat, internal insulation, lead Tropical and outer heat insulation layer；
The protection overcoat front end is equipped with end, and rear end is equipped with connector, in the side and connector rear end of connector The heart is respectively equipped with opening, and two openings are connected to by channel, and optical fiber is protruded into from the opening at connector rear end center, the company of entering At the side mouth of junctor；
The internal insulation and outer heat insulation layer are all hollow thin-wall cylinder, and thermal conductive belt is long arc shape sheet by a plurality of shape Structure composition；
The internal insulation is wrapped in the optical fiber periphery of connector rear end, thermally conductive to have multilayer, including Spaced setting Heat insulation layer periphery, each layer of thermally conductive spaced setting；Outer heat insulation layer is wrapped in thermal conductive belt periphery；
Internal insulation 3 is made with outer heat insulation layer 5 of flexible insulant material；Thermal conductive belt is made of graphite base heat conducting material；
The graphite base heat conducting material is prepared via a method which: first being added in suction funnel graphene oxide solution and is taken out Filter obtains graphene oxide membrane, and graphene oxide membrane is dry (molding of graphite base heat conducting material)；By the oxidation stone after drying Black alkene film, which immerses in filling solution, keeps 1~2h to take out dry (modification of graphite base heat conducting material)；Gained graphene oxide membrane It is clipped between two pieces of smooth graphite plates, applies pressure and be placed in tube furnace, 200 are first warming up in the case where CO is atmosphere~ 250 DEG C of 2~3h of holding cut off CO gas, with N2To protect gas, being warming up to 1200~1400 DEG C of 2~3h of holding, (graphite-based is thermally conductive The heat treatment of material)；For the solution of filling for the carbon tetrachloride solution of chromic formate, the mass ratio of chromic formate and carbon tetrachloride is 1: 10-20；In terms of mass fraction, 20~30 parts of solution, 70~80 parts of graphene oxide solution are filled；The graphene oxide solution Concentration be 4~6mg/ml.
To further realize the object of the invention, it is preferable that the connector rear end face of the protection overcoat is equipped with multiple tracks hole One end of slot, internal insulation, thermal conductive belt and outer heat insulation layer is all inserted into hole slot, is connect with connector.
Preferably, the internal insulation and outer heat insulation layer are all made of glass fibre, asbestos or aeroge.
Preferably, the thermal conductive belt is equipped with 2-6 layers.
Preferably, thermal conductive belt is formed by the graphite-based thermally-conductive sheet system of cutting.
Preferably, each interval of the thermal conductive belt is uniformly arranged at 4-20 item.
Preferably, the end of the protection overcoat front end is hemispherical dome structure, and the connector is column structure.
Preferably, the column rear end is circular flat.
Preferably, described by graphene oxide membrane drying is placed in graphene oxide membrane in 50~70 DEG C of vacuum drying ovens Dry 2~3h.
Preferably, it is by graphite oxide that the graphene oxide membrane, which immerses 1~2h of holding taking-up drying in filling solution, Alkene film, which is completely immersed in filling solution, keeps 1~2h to take out, dry 3~4h in 40~60 DEG C of vacuum ovens.
The present invention is based on the medical laser thermotherapy target heads of graphite-based composite heat conducting material to pass through graphite-based composite heat conducting material Heat is directed at separate optical fiber by conduction of heat, to prevent optical fiber head overheat even scaling loss.
Compared with the existing technology, the invention has the advantages that and the utility model has the advantages that
1) graphite-based material made of single layer or few layer graphene are constructed has excellent heating conduction, due to heat-treating oxygen Graphite alkene process, which generates gas, causes piece lamellar spacing to become larger, and during thermal reduction, the present invention is using carbon tetrachloride as carbon source, first Sour chromium generates chromium as catalyst during high temperature reduction, along chromium surrounding growth carbon nanotubes and filler piece lamellar spacing, thus Thermal conductivity between raising graphite flake layer, and then the entirety for improving graphite substrate continues heat-conducting effect.
2) conventional laser thermotherapy target head completes the heat dissipation of protection overcoat by water-cooling pattern, since laserthermia target head is whole Small in size, water flow velocity and limited flow in microchannel, heat exchange amount is few, carries out heat transfer using graphite-based composite heat conducting material Mode is significantly improved than traditional water-cooling pattern radiating efficiency, and graphite-based composite heat conducting material has high heat conductance, can will be protected Shield housing heat quickly exports to avoid protection overcoat overheat, and the one kind being prepared with graphite-based composite heat conducting material is medical to swash Photo-thermal treats target head, compares water-cooling pattern, does not need fluid conveying machine and transfer pipeline, reduce the complexity of structure, mitigates The total quality of target head is conducive to reduce wound wound area.
3) internal insulation of the present invention separates thermal conductive belt and optical fiber, prevents optical fiber side scaling loss, and outer heat insulation layer is by thermal conductive belt It is separated with tissue, prevents tissue of burn.
4) internal insulation of the present invention, outer heat insulation layer and optical fiber are all made of flexible materials, to torrid zone interval multilayer, every layer of warp Super-interval setting realizes flexible design, and medical laser thermotherapy target head of the present invention may be implemented bending and use, and is using target head The big blood vessel of human body or vitals can be avoided in the process, reduce Operative risk.
Detailed description of the invention:
Fig. 1 is the section SEM figure for heat-treating few layer graphene.
Fig. 2 is the section SEM figure obtained by embodiment based on graphite-based composite heat conducting material.
Fig. 3 is the Raman spectrogram of graphite-based composite heat conducting material obtained by embodiment.
Fig. 4 is that optical fiber in the medical laser thermotherapy target head based on graphite-based composite heat conducting material, internal insulation and protection are outer Connection figure between set.
Fig. 5 is to connect between thermal conductive belt and protection overcoat in the medical laser thermotherapy target head based on graphite-based composite heat conducting material Map interlinking.
Fig. 6 is for medical laser thermotherapy target head China and foreign countries' heat insulation layer based on graphite-based composite heat conducting material and between protection overcoat Connection figure.
Fig. 7 is protection overcoat facing groove distribution map.
It is shown in figure: protection overcoat 1, optical fiber 2, internal insulation 3, thermal conductive belt 4, outer heat insulation layer 5.
Specific embodiment
To keep the technical problem to be solved in the present invention, technical solution and advantage clearer, below in conjunction with specific implementation Example is described in detail, but embodiments of the present invention are unlimited so.
Such as Fig. 4-7, a kind of medical laser thermotherapy target head based on graphite-based composite heat conducting material, including it is protection overcoat 1, interior Heat insulation layer 3, thermal conductive belt 4 and outer heat insulation layer 5.
1 front end of protection overcoat is equipped with end, and rear end is equipped with connector, the side and connector rear end center point of connector It She You not be open, two openings are connected to by channel, and optical fiber 2 is protruded into from the opening at connector rear end center, enter connection At the side mouth of body；
Optical fiber 2 is cylinder, and when into column front end, optical fiber 2 is bent.Internal insulation 3 and outer heat insulation layer 5 are all hollow Thin walled cylindrical.Thermal conductive belt 4 is that long arc shape laminated structure forms by a plurality of shape.Internal insulation 3 is wrapped in connector rear end 2 periphery of optical fiber, thermal conductive belt 4 have multilayer, and Spaced setting is spaced setting in 3 periphery of internal insulation, each layer of thermal conductive belt 4； Outer heat insulation layer 5 is wrapped in 4 periphery of thermal conductive belt；
It is equipped with multiple tracks hole slot at the connector rear end face of protection overcoat 1, internal insulation 3, thermal conductive belt 4 and outer heat insulation layer 5 One end is all inserted into hole slot, is connect with connector.The connector rear end face of specifically protection overcoat 1 is equipped at intervals with outward from center 2 annular grooves, internal insulation 3 and outer heat insulation layer 5 are connected on connector by 2 annular grooves respectively；Twice annular groove it Between, the connector rear end face interval of protection overcoat 1 is provided with multiple tracks arc groove, thermal conductive belt 4 by spaced apart arc groove with Connector connection.
Internal insulation 3 is made with outer heat insulation layer 5 of flexible insulant material；Thermal conductive belt is made of graphite base heat conducting material；
Preferably, internal insulation 3 and outer heat insulation layer 5 are all made of glass fibre, asbestos or aeroge.Thermal conductive belt is equipped with 2- 6 layers.Thermal conductive belt is formed by the graphite-based thermally-conductive sheet system of cutting.The each interval of thermal conductive belt is uniformly arranged at 4-20 item.Protection overcoat The end of front end is hemispherical dome structure, and the connector is column structure.Column rear end is circular flat.
Since graphite-based composite heat-conducting fin has the characteristics of thermal conductivity is high, good mechanical properties, stabilization, light weight, and lead to It crosses cutting and in such a way that interval is wrapped to form the passage of heat, improves the radiating efficiency of target head, reduce target head quality and volume, simultaneously Be intervally arranged can, make target head have higher bending degree, make target head when in use can by bending avoid vitals or Big blood vessel improves therapeutic effect.
Cooperate Medical Imaging Technology when medical laser thermotherapy target head use of the invention, is guided target head to phase by puncturing Answer treatment position.
Embodiment 1
One kind being based on graphite-based composite heat conducting material, is made of the component of following parts by weight: 80 parts of graphene oxide (concentration 4mg/ml), (solute is chromic formate to 20 parts of filling agent solutions, and solvent is carbon tetrachloride, wherein the matter of chromic formate and carbon tetrachloride Amount is than being 1:15).
A kind of preparation method based on graphite-based composite heat conducting material, comprising the following steps:
1) 6ml graphene oxide solution is added dropwise to suction filtration 2h in suction funnel and obtains graphene oxide membrane, stone will be aoxidized Black alkene film is placed in 70 DEG C of vacuum drying ovens dry 2h.
2) graphene oxide membrane after drying is completely immersed in filling agent solution keeps 1h to take out, and is dried in vacuo at 50 DEG C Dry 4h obtains modified graphite piece in case.
3) modified graphite flake is clipped between two pieces of smooth graphite plates, applies 10MPa pressure and is placed in pipe In formula furnace, it is first warming up to 200 DEG C of holding 3h under CO atmosphere, then cuts off CO gas supply, is passed through N2And it is warming up to 1200 DEG C of holdings 3h。
Test results are shown in figure 3 for 1 Raman of the gained based on graphite-based composite heat conducting material of embodiment, wherein the peak D and the peak G Ratio be used to characterize the defect concentration of graphite, be worth smaller, show that its defect is fewer, the peak D of graphite flake is lower than the peak G in figure, Intensity rate is about 0.9, lower than directly heat-treating obtained redox graphene, about 1.5.The peak Raman analysis D and the peak G point Cloth illustrates that the defect of modified graphite piece is reduced, and filler, which is added, can also reduce the defect of graphite flake layer.
Graphite-based composite heat conducting material and only do not pass through suction funnel suction filtration in the immersion of filling agent solution prepared by embodiment 1 And the thermal diffusion coefficient for the thermal reduction graphite flake being prepared with identical thermal reduction technique is obtained by laser heat conducting instrument measurement, than Heat is obtained by differential scanning calorimetry instrument measurement, and tensile strength is obtained by universal testing machine measurement.Thermal diffusion coefficient, specific heat with Tensile strength is as shown in table 1.
Table 1
Type Thermal diffusion coefficient (mm2·s-1) Specific heat (J/g-1·k-1) Tensile strength (MPa)
Heat-treat graphite flake 1147.6 0.68 7.4
Graphite-based composite heat conducting material 1856.4 0.71 10.8
According to Determination of conductive coefficients standard ASTM E14061-01, the thermal conductivity of material is equal to thermal diffusion under its corresponding temperature The product of coefficient, specific heat and density calculates separately to obtain graphite-based composite heat conducting material thermal conductivity to be 874Wm-1k-1, heat is also Former graphite flake thermal conductivity is 412Wm-1k-1。
1 scanning electron microscope result of the gained based on graphite-based composite heat conducting material of embodiment is as shown in Fig. 2, comparison diagram 1 is direct Obtained graphene is heat-treated, between graphite flake layer since the carbon dioxide gas that reduction generates is discharged after high-temperature heat treatment So that longitudinal thermal conductivity of interlayer is substantially reduced in contrast, the modification stone of filler is added in the existing biggish phenomenon of piece interlamellar spacing Black alkene, since while piece interlamellar spacing increases during thermal reduction, using carbon tetrachloride as carbon source, chromic formate obtains for catalyst growth It is filled with piece lamellar spacing to carbon nanotubes, to form passage of heat in piece interlayer, hence it is evident that improve interlayer thermal conductivity, also from heat Former graphite flake thermal conductivity is 412Wm-1k-1Being increased to the present embodiment graphite-based composite heat conducting material thermal conductivity is 874Wm-1k-1。
A kind of medical laser thermotherapy target head based on graphite-based composite heat conducting material, thermal conductive belt 4 are that the present embodiment is resulting It is prepared based on graphite-based composite heat conducting material, by about 80 millimeters of the diameter of preparation, with a thickness of 0.5mm graphite-based composite heat-conducting material Material is formed as a length of 60mm, width is the strip of 30~35mm, and protection overcoat 1 is titanium alloy material, and optical fiber 2 is stone by cutting English material, internal insulation 3 and outer heat insulation layer 5 are aerogel material.
Thermal conductive belt 4 is prolonged width direction and is bent and respectively corresponds in insertion by the resulting medical laser thermotherapy target head of embodiment 1 Arc groove between 5 annular groove of 3 annular groove of heat insulation layer and outer heat insulation layer, the arrangement of arc groove are prolonged radial direction and are shared from inside to outside Four layers, each interlayer is every being uniformly distributed four identical arc grooves.
Compared with the rigid all-metal water cooling target head that the prior art mostly uses, since the thermal conductivity of thermal conductive belt is copper, silver etc. Twice of metal, is 35W by heat exchange pattern heat exchange amount, and the same terms water cooling heat exchange amount is 15W, and passes through heat compared to water cooling The mode of conduction, which radiates, avoids metal water-cooling there are target head volume is big, and microchannel processing difficulties need to configure fluid conveyer The problems such as tool.The graphite-base composite material that thermal conductive belt 4 uses, the materials such as aerogel material that internal insulation 3, outer heat insulation layer 5 use Material, quality is all very light, reduces target head weight.Due to the optical fiber 2 being connected with protection overcoat, internal insulation 3, outer heat insulation layer 5 is For flexible material, and 4 preparation method of thermal conductive belt and material combination, and by way of being intervally arranged, be conducive to improve it is flexible, The medical laser thermotherapy target head being prepared can be tightly attached to the cylindrical side that diameter is 80mm, and the medical thermotherapy of multilayer package Target head tensile strength is 10MPa, meets requirement.The resulting medical laser thermotherapy target head light structure of the present embodiment 1, favorably In reducing wound wound area, simultaneously as having good bending performance, make target head that can avoid human body in use Big blood vessel or vitals, reduce Operative risk.
Embodiment 2
One kind being based on graphite-based composite heat conducting material, is made of the component of following parts by weight: 75 parts of graphene oxide (concentration 4mg/ml), (solute is chromic formate to 25 parts of filling agent solutions, and solvent is carbon tetrachloride, wherein the matter of chromic formate and carbon tetrachloride Amount is than being 1:10).
A kind of preparation method based on graphite-based composite heat conducting material, comprising the following steps:
1) 8ml graphene oxide solution is added dropwise to suction filtration 2h in suction funnel and obtains graphene oxide membrane, stone will be aoxidized Black alkene film is placed in 60 DEG C of vacuum drying ovens dry 2h.
2) graphene oxide membrane after drying is completely immersed in filling agent solution keeps 2h to take out, and is dried in vacuo at 40 DEG C Dry 3h obtains modified graphite piece in case.
3) modified graphite flake is clipped between two pieces of smooth graphite plates, applies 10MPa pressure and is placed in pipe In formula furnace, it is first warming up to 250 DEG C of holding 3h under CO atmosphere, then cuts off CO gas supply, is passed through N2And it is warming up to 1400 DEG C of holdings 2h。
The test result for the graphite-based composite heat conduction film that embodiment 2 is prepared is substantially the same manner as Example 1.
A kind of medical laser thermotherapy target head based on graphite-based composite heat conducting material, thermal conductive belt 4 are that the present embodiment is resulting Based on graphite-based composite heat conducting material prepare, by preparation be cut to a thickness of 0.6mm graphite-based composite heat conducting material it is a length of 60mm, width be 30~40mm strip, protection overcoat 1 be titanium alloy material, optical fiber 2 be quartz material, internal insulation 3 and it is outer absolutely Thermosphere 5 is asbestos material.
Thermal conductive belt 4 is prolonged width direction and is bent and respectively corresponds in insertion by the resulting medical laser thermotherapy target head of embodiment 2 Arc groove between 5 annular groove of 3 annular groove of heat insulation layer and outer heat insulation layer, the arrangement of arc groove are prolonged radial direction and are shared from inside to outside Five layers, each interlayer is every being uniformly distributed five identical arc grooves.
Compared with the rigid all-metal water cooling target head that the prior art mostly uses, since the thermal conductivity of thermal conductive belt is copper, silver etc. Twice of metal, is 41W by heat exchange pattern heat exchange amount, and the same terms water cooling heat exchange amount is 15W, and passes through heat compared to water cooling The mode of conduction, which radiates, avoids metal water-cooling there are target head volume is big, and microchannel processing difficulties need to configure fluid conveyer The problems such as tool.The asbestos material quality of graphite-base composite material and internal insulation 3, the use of outer heat insulation layer 5 that thermal conductive belt 4 uses is very Gently, target head weight is reduced.Due to the optical fiber 2 being connected with protection overcoat, internal insulation 3, thermal conductive belt 4, outer heat insulation layer 5 is soft Property material, and 4 preparation method of thermal conductive belt and material combination, and be conducive to improve flexible, preparation by way of being intervally arranged Obtained medical laser thermotherapy target head can be tightly attached to the cylindrical side that diameter is 70mm, and the medical thermotherapy target head of multilayer package Tensile strength is 9MPa, meets requirement.Therefore, the resulting medical laser thermotherapy target head light structure of embodiment, is conducive to Reduce wound wound area, simultaneously as having good bending performance, makes target head that can avoid human body in use big Blood vessel or vitals reduce Operative risk.
Embodiment 3
One kind being based on graphite-based composite heat conducting material, is made of the component of following parts by weight: 70 parts of graphene oxide (concentration 6mg/ml), (solute is chromic formate to 30 parts of filling agent solutions, and solvent is carbon tetrachloride, wherein the matter of chromic formate and carbon tetrachloride Amount is than being 1:20).
A kind of preparation method based on graphite-based composite heat conducting material, comprising the following steps:
1) 6ml graphene oxide solution is added dropwise to suction filtration 2h in suction funnel and obtains graphene oxide membrane, stone will be aoxidized Black alkene film is placed in 50 DEG C of vacuum drying ovens dry 3h.
2) graphene oxide membrane after drying is completely immersed in filling agent solution keeps 2h to take out, and is dried in vacuo at 50 DEG C Dry 4h obtains modified graphite piece in case.
3) modified graphite flake is clipped between two pieces of smooth graphite plates, applies 10MPa pressure and is placed in pipe In formula furnace, it is first warming up to 250 DEG C of holding 3h under CO atmosphere, then cuts off CO gas supply, is passed through N2And it is warming up to 1300 DEG C of holdings 3h。
The test result for the graphite-based composite heat conduction film that embodiment 3 obtains is substantially the same manner as Example 1.
A kind of medical laser thermotherapy target head based on graphite-based composite heat conducting material, thermal conductive belt 4 are that the present embodiment is resulting Based on graphite-based composite heat conducting material prepare, by preparation be cut to a thickness of 0.4mm graphite-based composite heat conducting material it is a length of 60mm, width be 25~30mm strip, protection overcoat 1 be titanium alloy material, optical fiber 2 be quartz material, internal insulation 3 and it is outer absolutely Thermosphere 5 is glass fiber material.
Thermal conductive belt 4 is prolonged width direction and is bent and respectively corresponds in insertion by the resulting medical laser thermotherapy target head of embodiment 3 Arc groove between 5 annular groove of 3 annular groove of heat insulation layer and outer heat insulation layer, the arrangement of arc groove are prolonged radial direction and are shared from inside to outside Three layers, each interlayer is every being uniformly distributed five identical arc grooves.
Compared with the rigid all-metal water cooling target head that the prior art mostly uses, since the thermal conductivity of thermal conductive belt is copper, silver etc. Twice of metal, is 25W by heat exchange pattern heat exchange amount, and the same terms water cooling heat exchange amount is 15W, and passes through heat compared to water cooling The mode of conduction, which radiates, avoids metal water-cooling there are target head volume is big, and microchannel processing difficulties need to configure fluid conveyer The problems such as tool.The glass fiber material matter of graphite-base composite material and internal insulation 3, the use of outer heat insulation layer 5 that thermal conductive belt 4 uses Amount is very light, reduces target head weight.Due to the optical fiber 2 being connected with protection overcoat, internal insulation 3, thermal conductive belt 4, outer heat insulation layer 5 is For flexible material, and 4 preparation method of thermal conductive belt and material combination, and by way of being intervally arranged be conducive to improve it is flexible, The medical laser thermotherapy target head being prepared can be tightly attached to the cylindrical side that diameter is 85mm, and the medical thermotherapy of multilayer package Target head tensile strength is 7MPa, meets requirement.Therefore, the resulting medical laser thermotherapy target head light structure of embodiment, has Conducive to wound wound area is reduced, simultaneously as having good bending performance, make target head that can avoid people in use The big blood vessel of body or vitals reduce Operative risk.

Claims (10)

1. a kind of medical laser thermotherapy target head based on graphite-based composite heat conducting material, which is characterized in that including protection overcoat, interior Heat insulation layer, thermal conductive belt and outer heat insulation layer；
The protection overcoat front end is equipped with end, and rear end is equipped with connector, the side and connector rear end center point of connector It She You not be open, two openings are connected to by channel, and optical fiber is protruded into from the opening at connector rear end center, enter connector Side mouth at；
The internal insulation and outer heat insulation layer are all hollow thin-wall cylinder, and thermal conductive belt is long arc shape laminated structure by a plurality of shape Composition；
The internal insulation is wrapped in the optical fiber periphery of connector rear end, thermally conductive to have multilayer, and Spaced setting is insulated inside Layer periphery, each layer of thermally conductive spaced setting；Outer heat insulation layer is wrapped in thermal conductive belt periphery；
Internal insulation is made with outer heat insulation layer of flexible insulant material；Thermal conductive belt is made of graphite base heat conducting material；
The graphite base heat conducting material is prepared via a method which: first being added in suction funnel graphene oxide solution and is filtered It is to graphene oxide membrane, graphene oxide membrane is dry；By after drying graphene oxide membrane immerse filling solution in keep 1~ 2h takes out drying；Gained graphene oxide membrane is clipped between two pieces of smooth graphite plates, is applied pressure and is placed in tube furnace, 200~250 DEG C of 2~3h of holding are first warming up in the case where CO is atmosphere, CO gas are cut off, with N2To protect gas, it is warming up to 1200~ 1400 DEG C of 2~3h of holding；For the carbon tetrachloride solution of chromic formate, the mass ratio of chromic formate and carbon tetrachloride is the solution of filling 1:10-20；In terms of mass fraction, 20~30 parts of solution, 70~80 parts of graphene oxide solution are filled；The graphene oxide is molten The concentration of liquid is 4~6mg/ml.
2. the medical laser thermotherapy target head according to claim 1 based on graphite-based composite heat conducting material, it is characterised in that: The connector rear end face of the protection overcoat is equipped with multiple tracks hole slot, and one end of internal insulation, thermal conductive belt and outer heat insulation layer is all inserted Enter in hole slot, is connect with connector.
3. the medical laser thermotherapy target head according to claim 1 based on graphite-based composite heat conducting material, it is characterised in that: The internal insulation and outer heat insulation layer are all made of glass fibre, asbestos or aeroge.
4. the medical laser thermotherapy target head according to claim 1 based on graphite-based composite heat conducting material, it is characterised in that: The thermal conductive belt is equipped with 2-6 layers.
5. the medical laser thermotherapy target head according to claim 1 based on graphite-based composite heat conducting material, it is characterised in that: Thermal conductive belt is formed by the graphite-based thermally-conductive sheet system of cutting.
6. the medical laser thermotherapy target head according to claim 1 based on graphite-based composite heat conducting material, it is characterised in that: The each interval of the thermal conductive belt is uniformly arranged at 4-20 item.
7. the medical laser thermotherapy target head according to claim 1 based on graphite-based composite heat conducting material, it is characterised in that: The end of the protection overcoat front end is hemispherical dome structure, and the connector is column structure.
8. the medical laser thermotherapy target head according to claim 7 based on graphite-based composite heat conducting material, it is characterised in that: The column rear end is circular flat.
9. the medical laser thermotherapy target head according to claim 1 based on graphite-based composite heat conducting material, it is characterised in that: Described is that graphene oxide membrane is placed in in 50~70 DEG C of vacuum drying ovens dry 2~3h by graphene oxide membrane drying.
10. the medical laser thermotherapy target head according to claim 1 based on graphite-based composite heat conducting material, feature exist In: it is to be completely immersed in graphene oxide membrane that the graphene oxide membrane, which immerses 1~2h of holding taking-up drying in filling solution, Filling in solution keeps 1~2h to take out, dry 3~4h in 40~60 DEG C of vacuum ovens.
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