CN108671095A

CN108671095A - A kind of preparation method and Chinese medicine preparation patch for alleviating the Chinese medicine composition of ophthalmic uncomfortable disease, herb liquid

Info

Publication number: CN108671095A
Application number: CN201810827585.2A
Authority: CN
Inventors: 晁楚杰; 王峰
Original assignee: Individual
Current assignee: Individual
Priority date: 2018-07-25
Filing date: 2018-07-25
Publication date: 2018-10-19

Abstract

The present invention relates to eye health protection articles for use fields, in particular to the preparation method and Chinese medicine preparation patch of a kind of Chinese medicine composition for alleviating ophthalmic uncomfortable disease, herb liquid.The Chinese medicine composition includes：In parts by weight, 10~14 parts of monarch drug in a prescription and 8~12 parts of ministerial drug；The monarch drug in a prescription is made of butterflybush flower, climbing groundsel, pipewort, the butterflybush flower, climbing groundsel, pipewort mass ratio be 0.8~1.2：0.8~1.2：0.8~1.2, the ministerial drug is made of cassia seed, the coptis, chamomile, holy basil, the cassia seed, the coptis, chamomile, holy basil mass ratio be 0.8~1.2：0.8~1.2：0.8~1.2：0.8~1.2.The present invention is formulated reasonable design using science of TCM formulas as theoretical foundation, and preferable mitigation is played to diseases such as the eye of eye is dry, eye is puckery, asthenopia, itch, eye-blurred, redness, muscae volitantes, rainbow conjunctivitis, it is curative for effect, take effect it is rapid.

Description

It is a kind of alleviate the Chinese medicine composition of ophthalmic uncomfortable disease, herb liquid preparation method and in Medicine preparation patch

Technical field

The present invention relates to eye health protection articles for use fields, in particular to a kind of Chinese traditional medicine composition for alleviating ophthalmic uncomfortable disease Object, the preparation method of herb liquid and Chinese medicine preparation patch.

Background technology

In recent years, with the fast development of electronic science and technology, high-tech electronic class product and video class electronic equipment are deep Enter each corner lived to people.It is that reading is read newspaper that people, which obtained information mostly, in the past, and the influence to eyesight is smaller.Present people Obtain information it is mostly be by seeing the mobile phone, computer or television, and due to the attractability of content, most people eye closes for a long time The time for noting a certain electrical type equipment is longer compared with reading is seen and calls time, then 20 minutes short, it is long then up to 180 minutes or so, very It is longer to the time, optic nerve fatigue is resulted in, the eyesight of people is horizontal whole on a declining curve in the course of time.

Chinese medicine is early finalized the thing for crossing pole, is meaning general debility, impairment of blood by looking for a long time, Lao Yuxin.Concern electrical type for a long time Product not only results in visual impairment, meanwhile, have certain influence again on the motive.Present not only young man, even a middle-aged person is Have to stay up late to see the mobile phone and play the custom of computer, occurs 25 years old patient for occurring as soon as palpitation and short breath in clinical example, this kind of people plays computer expert 1 point of Chang Lingchen just rests, and declines within eyesight 1 year apparent.

It to the treatment of eye and releives in the prior art and common are oral medicine, eye drops and eye ointment, and eye sticker, mostly send out Heat is releived eye sticker, or rich in eye nutritional ingredient such as glycerine, water etc., is more closely similar to be the outer patch with eye drops, product Effect is mostly also not fully up to expectations.

In view of this, special propose the present invention.

Invention content

The first object of the present invention is to provide a kind of Chinese medicine composition for alleviating ophthalmic uncomfortable disease, the Chinese traditional medicine composition Object is made of monarch drug in a prescription and ministerial drug, can be to the eye of eye is dry, eye is puckery, asthenopia, itches, eye-blurred, redness, muscae volitantes, rainbow knot The diseases such as film inflammation play preferable mitigation, it is curative for effect, take effect it is rapid.

The second object of the present invention is to provide a kind of preparation method of herb liquid that alleviating ophthalmic uncomfortable disease, the herb liquid Using above-mentioned Chinese medicine composition as raw material, the preparation method is easy to operate, safe.

The third object of the present invention is to provide a kind of Chinese medicine preparation patch that ophthalmic uncomfortable disease is effectively relieved, and the patch is steady Dingan County is complete, it is easy to use, be readily produced.

In order to realize that the above-mentioned purpose of the present invention, spy use following technical scheme：

A kind of Chinese medicine composition for alleviating ophthalmic uncomfortable disease, the Chinese medicine composition include：In parts by weight, 10~14 parts Monarch drug in a prescription and 8~12 parts of ministerial drug；The monarch drug in a prescription is made of butterflybush flower, climbing groundsel, pipewort, the butterflybush flower, climbing groundsel, paddy The mass ratio of smart grass is 0.8~1.2：0.8~1.2：0.8~1.2；The ministerial drug is by cassia seed, the coptis, chamomile, holy basil Composition；The cassia seed, the coptis, chamomile, holy basil mass ratio be 0.8~1.2：0.8~1.2：0.8~1.2：0.8~ 1.2。

All raw materials are all in inventive formulation《Chinese Pharmacopoeia》Upper contained kind, is national essential drugs, matches Side is studied by galenic pharmacy, to the eye of eye is done, eye is puckery, asthenopia, itches, eye-blurred, redness, muscae volitantes, rainbow knot The common ophthalmic uncomfortable problem such as film inflammation plays preferable mitigation, it is curative for effect, take effect it is rapid.

Monarch drug in a prescription of the present invention is made of butterflybush flower, climbing groundsel, pipewort, the butterflybush flower, climbing groundsel, pipewort mass ratio It is 0.8~1.2：0.8~1.2：0.8~1.2.Monarch drug in a prescription is the noun in science of TCM formulas, is risen mainly for main disease or main symptom The drug of therapeutic effect.It is indispensable in the side of being, and the drug that the efficacy of a drug tops the list.Such as in some embodiments, the group of the monarch drug in a prescription At can also be 0.8 part of butterflybush flower, 0.8 part of climbing groundsel, 0.8 part of pipewort；0.8 part of butterflybush flower, 1.0 parts of climbing groundsel, pipewort 0.8 part；1.0 parts of butterflybush flower, 0.8 part of climbing groundsel, 1.2 parts of pipewort；1.0 parts of butterflybush flower, 1.0 parts of climbing groundsel, pipewort 1.0 Part；1.0 parts of butterflybush flower, 1.2 parts of climbing groundsel, 1.0 parts of pipewort；0.8 part of butterflybush flower, 1.0 parts of climbing groundsel, 1.2 parts of pipewort；It is close Illiteracy spend 1.2 parts, 1.2 parts of climbing groundsel, 1.2 parts of pipewort；1.2 parts of butterflybush flower, 1.0 parts of climbing groundsel, 0.8 part of pipewort etc. (this Result is almost the same in range).

Butterflybush flower also known as：It contaminates meal flower, kamuning, native brocade flower, cover flower, yellow meal flower, pimple skin tree, chicken bone flower, be horse Qian Ke, Lindley Butterflybush Herb category shrub.It is medicinal effects that it, which dries flower or bud, plays the role of wind-dispelling, cool blood, profit liver, improving eyesight, can control mesh Red swelling and pain, more tear photophobia, glaucoma ocular, the rotten eye of wind string.

Climbing groundsel also known as nine inner bright, Herba Senecionis Scandentis, HERBA SENECIONIS SCANDENTIS, bright stroke of eye, sweet vernal grass Broomjutre Sida Herb, Kowloon light, nine ridge light.For chrysanthemum Section herbaceous plant, cold in nature, bitter have clearing heat and detoxicating, improving eyesight, antipruritic and other effects.

Pipewort (scientific name：Eriocaulon buergerianum) also known as Dai Xingcao, Wen Xingcao, meteor grass, TianXing grass. Chinese most areas are used as medicine with the plant herb as pipewort, are harvested, are dried when fall flowering beads up.Can dispelling wind and heat from the body, improving eyesight Move back screen.For wind-heat of liver channel, red eye, swell pain, mesh life ocular, headache due to pathogenic wind-heat.

For the application with butterflybush flower, climbing groundsel, pipewort altogether for monarch drug in a prescription, red and swollen ocular, red puckery more can be moved back by entering the liver channel of foot-Jueyin Tear.

Ministerial drug of the present invention is made of cassia seed, the coptis, chamomile, holy basil, the cassia seed, the coptis, chamomile, zero mound Fragrant mass ratio is 0.8~1.2：0.8~1.2：0.8~1.2；0.8~1.2.Ministerial drug be auxiliary monarch drug in a prescription reinforce treatment it is main disease or Main symptom or the drug that therapeutic effect is played for simultaneous disease or accompanying symptoms, the efficacy of a drug in prescription are less than monarch drug in a prescription.Such as in some implementations Example in, the cassia seed, the coptis, chamomile, holy basil composition can also be：0.8 part of cassia seed, 0.8 part of the coptis, chamomile 0.8 part, 0.8 part of holy basil；0.8 part of cassia seed, 1.0 parts of the coptis, 0.8 part of chamomile, 1.0 parts of holy basil；1.0 parts of cassia seed, 1.0 parts of the coptis, 1.0 parts of chamomile, 1.0 parts of holy basil；1.0 parts of cassia seed, 0.8 part of the coptis, 1.2 parts of chamomile, holy basil 1.2 Part；1.2 parts of cassia seed, 1.2 parts of the coptis, 1.2 parts of chamomile, 1.2 parts of holy basil；1.2 parts of cassia seed, 1.0 parts of the coptis, chamomile 1.2 parts, 1.2 parts of holy basil etc. (result is almost the same within the scope of this).

Cassia seed, Chinese medicine name also known as horseshoe Cassia, blunt leaf Cassia, false mung bean, Cassia occidentalis.It is legume Cassia or small The dry mature seed of Cassia, with its have improving eyesight work(and name it.Cassia seed bitter, sweet, salty, cold nature enters liver, kidney, large intestine Through；It relaxes bowel, constipation and hyperlipidemia, hypertension are treated in lipid-loweringing improving eyesight.

The coptis, (scientific name：Coptis chinensis Franch.) alias：Taste connects, river connects, Rhizoma Coptidis, belongs to Ranunculaceae, Huang Even belong to herbaceos perennial.Coptis major function is heat-clearing and damp-drying drug, purging intense heat and detonicating, for damp and hot feeling of fullness, vomiting, rush down dysentery, Huang Subcutaneous ulcer unconsciousness due to high fever, heart-fire hyperactivity, dysphoria and insomnia, hot eyes acid regurgitation, has a toothache, quenches one's thirst and carbuncle swells furunculosis, control eczema, wet sore, duct outside It suppurates.

Chamomile is feverfew also known as Rome chamomile, German chamomile.Its mildly bitter flavor, Gan Xiang, materials for improving vision move back liver Fire, treatment have a sleepless night and reduce blood pressure.

Holy basil also known as smoked grass, swallow grass, a species of orchid grass, vanilla, bell bell perfume, bell perfume, yellow zero grass, stacte, mound grass, are dicotyledonous The whole herb with root of autonomic drug Ofthe Primulaceae Lysimachia foenum-graecum, main improving eyesight stop tear, treat and let out essence, deodorizing bad odor, cold headache, upper gas, Pain in the back.

The present invention using cassia seed, the coptis, chamomile, holy basil as ministerial drug, can heat-clearing and damp-drying drug, purging intense heat and detonicating, anti-inflammatory.

Monarch drug in a prescription is to play the drug of primary treatment for main disease or main symptom in science of TCM formulas, and principal drug assistance adds supplemented by ministerial drug Main disease or main symptom are treated by force or the drug of therapeutic effect is played for simultaneous disease or accompanying symptoms.Therefore, the dosage of monarch drug in a prescription should be greater than ministerial drug. For example, in some embodiments, the composition of the Chinese medicine composition can also be 11 parts of monarch drug in a prescription, 8 parts of ministerial drug；12 parts of monarch drug in a prescription, 8 parts of ministerial drug；12 parts of monarch drug in a prescription, 9 parts of ministerial drug；13 parts of monarch drug in a prescription, 10 parts of ministerial drug；14 parts of monarch drug in a prescription, 8 parts of ministerial drug；14 parts of monarch drug in a prescription, ministerial drug 11 Part；14 parts of monarch drug in a prescription, 12 parts of ministerial drug；14 parts of monarch drug in a prescription, 13 parts of ministerial drug；13 parts of monarch drug in a prescription, 9 parts of ministerial drug etc..

Preferably, the Chinese medicine composition further includes 6~10 parts of adjutant, and the adjutant is one kind of moutan bark, Radix Salviae Miltiorrhizae Or it is a variety of；The mass ratio of the moutan bark and Radix Salviae Miltiorrhizae is 0.8~1.2：0.8~1.2.

Adjutant, i.e. assistance monarch, ministerial drug is to reinforce therapeutic effect, or directly treats the drug of secondary accompanying symptoms, and adjutant is in side The efficacy of a drug be less than ministerial drug, general dosage is lighter.As in some embodiments, the composition of the adjutant further include 0.8 part of moutan bark, 0.8 part of Radix Salviae Miltiorrhizae；0.8 part of tree peony, 1.0 parts of Radix Salviae Miltiorrhizae；1.0 parts of moutan bark, 1.0 parts of Radix Salviae Miltiorrhizae；1.2 parts of moutan bark, 1.2 parts of Radix Salviae Miltiorrhizae；It is male (result are almost the same within the scope of this) such as 1.2 parts of the root bark of tree peony, 0.8 part of Radix Salviae Miltiorrhizaes.

Moutan bark is ranunculaceae peony dry root skin also known as moutan root bark, the root bark of tree peony, red root.It is its bitter, pungent, it is slightly cold, The thoughts of returning home, liver and kidney channel have clearing heat and cooling blood, activate blood circulation and disperse blood clots, reducing the asthenic fever and other effects.

Dry root and rhizome also known as red root that Radix Salviae Miltiorrhizae is labiate Radix Salviae Miltiorrhizae Salvia miltiorrhiza Bge., Clovershrub, blood join root.It is inducing meastruation to relieve menalgia with promoting blood circulation, the effect of relieving restlessness that clears away heart-fire, cool blood to disappear carbuncle.For chest impediment and cardialgia, gastral cavity abdomen Hypochondriac pain, the accumulation of lump in the abdomen lump in the abdomen, hot numbness pain, dysphoria and insomnia, irregular menstruation, dysmenorrhoea Amenorrhea, sore swell and ache curative.

Moutan bark, Radix Salviae Miltiorrhizae are adjutant, coordinate main pharmacological property, and can enliven the blood of part.

Adjutant assists monarch, ministerial drug to reinforce therapeutic effect, by Chinese medicine pharmacy, the dosage of monarch drug in a prescription should be greater than ministerial drug, minister The dosage of medicine should be greater than adjutant.In some embodiments, the monarch drug in a prescription, ministerial drug, adjutant composition can also be 10 parts of monarch drug in a prescription, minister 8 parts of medicine, 6 parts of adjutant；14 parts of monarch drug in a prescription, 12 parts of ministerial drug, 10 parts of adjutant；11 parts of monarch drug in a prescription, 9 parts of ministerial drug, 7 parts of adjutant；12 parts of monarch drug in a prescription, 10 parts of ministerial drug, 8 parts of adjutant；13 parts of monarch drug in a prescription, 8 parts of ministerial drug, 7 parts of adjutant；14 parts of monarch drug in a prescription, 11 parts of ministerial drug, 9 parts of adjutant；Monarch drug in a prescription 13 Part, 8 parts of ministerial drug, 6 parts of adjutant；12 parts of monarch drug in a prescription, 9 parts of ministerial drug, 7 parts of adjutant；11 parts of monarch drug in a prescription, 10 parts of ministerial drug, 7 parts of adjutant；Monarch drug in a prescription 10 Part, 8 parts of ministerial drug, 7 parts of adjutant；12 parts of monarch drug in a prescription, 9 parts of ministerial drug, 6 parts of adjutant etc..

Preferably, the Chinese medicine composition further includes 3~6 parts of the medicine that makes, described that medicine is made to be ginseng, grass-leaved sweetflag, Radix Codonopsis, stone Dry measure used in former times, pearl, menthol, borneol, the ginseng, grass-leaved sweetflag, Radix Codonopsis, the stem of noble dendrobium, pearl, menthol, borneol mass ratio be 0.8~ 1.2：0.8~1.2：0.8~1.2：0.8~1.2：0.8~1.2：0.8~1.2：0.8~1.2.

It is guiding drug to make medicine, can in the side of drawing all medicines with up to disease drug；Or harmonizing drug, i.e., with coordinating the drug actions of a prescription effect Drug.As in some embodiments, ginseng, grass-leaved sweetflag, Radix Codonopsis, the stem of noble dendrobium, pearl, menthol, borneol composition can also be：People 0.8 part of ginseng, 0.8 part of grass-leaved sweetflag, 0.8 part of Radix Codonopsis, 0.8 part of the stem of noble dendrobium, 0.8 part of pearl, 0.8 part of menthol, 0.8 part of borneol；Ginseng 1.0 parts, 1.0 parts of grass-leaved sweetflag, 1.0 parts of Radix Codonopsis, 1.0 parts of the stem of noble dendrobium, 1.0 parts of pearl, 1.0 parts of menthol, 1.0 parts of borneol；Ginseng 1.2 parts, 1.2 parts of grass-leaved sweetflag, 1.2 parts of Radix Codonopsis, 1.2 parts of the stem of noble dendrobium, 1.2 parts of pearl, 1.2 parts of menthol, 1.2 parts of borneol；Ginseng 0.8 Part, 1.2 parts of grass-leaved sweetflag, 1.2 parts of Radix Codonopsis, 1.0 parts of the stem of noble dendrobium, 1.0 parts of pearl, 0.8 part of menthol, 1.2 parts of borneol；Ginseng 1.0 (this range such as part, 1.0 parts of grass-leaved sweetflag, 1.0 parts of Radix Codonopsis, 0.8 part of the stem of noble dendrobium, 0.8 part of pearl, 1.2 parts of menthol, 1.0 parts of borneol Interior result is almost the same).

Ginseng (scientific name：Panax ginseng) it is herbaceos perennial, the weather of shady and cool moistening is liked, is also known as Huang Ginseng, Goblin, god grass, King of Herbs, main tonifying five zang organs, soothe the nerves, stop palpitate with fear, remove pathogenic factor, improving eyesight, happy intelligence development can reinforce vital energy, Veins takes off admittedly reinforces the spleen to benefit the lung, and promotes the production of body fluid to quench thirst.

Grass-leaved sweetflag (Classification system：Acorus tatarinowii), belong to Araeceae, Acorus graminoid perennial herb Plant, rhizome have smell.Also known as acorus graminens soland, mountain calamus, medicine calamus, money Pu, grassleaf sweetflag leaf, water sword grass, white flag.Acrid flavour It is warm-natured, have the gas of fragrance, the scattered power of row is stronger, for the good merchantable brand for declaring gas sensible, can remove dampness by means of aromatics, activating spleen and strengthening stomach and change turbid Eliminating the phlegm has one's ideas straightened out and allays excitement.

Radix Codonopsis (scientific name；Codonopsis pilosula (Franch.) Nannf.) Campanulaceae Codonopsis also known as windproof party Ginseng, kurarinone, preventing lanceolata, upper Radix Codonopsis, SHITOUSEN, middle spirit grass, Huang Dang, for the common traditional tonic of China, ancient times are on Shanxi The Radix Codonopsis that party area produces is top grade, has the effect of tonifying middle-Jiao and Qi, strengthening spleen and tonifying lung.Radix Codonopsis have strengthen immunity, expansion blood vessel, Decompression improves the effects that microcirculation, enhancing hematopoiesis function.

The stem of noble dendrobium (scientific name：Dendrobium nobile Lindl), also known as celestial dry measure used in former times orchid rhythm, not dead grass, whorlleaf stonecrop herb, purple entangle celestial being Strain, bracketplant, Lin Lan, prohibition of life, nobile flower etc..Medicinal plant, property slightly sweet flavor is micro- salty, trembles with fear, returns stomach, kidney, lung channel.Reinforcing stomach reg fluid is grown Cloudy heat-clearing.For impairment of yin body fluid deficiency, dry polydipsia, deficiency of food is retched, and abnormal heat, mesh are secretly unknown after being ill.

Pearl also known as natural pearls, pearl inside the body of a freshwater mussel, natural pearls, medicine pearl, pearl, Lian pearl belong to animal medicinal material, Pteriidae animal pearl The nothing formed in the shell-fishes pearl sac such as shellfish, Pinctada martensii or Unionidae animal hydriopsis cumingii, cristaria plicata, anodonta woodiana pacifica Nucleus pearl can be used as medicine.With arresting convulsion of calming the nerves, shade removing, solution taking poison and growing muscle due and other effects, modern study also shows that pearl is improving people Body immunity, anti-aging, freckle removing and whitening, supplement calcium etc. all have unique effect.

Menthol, Chinese medicine name, for the crystallization extracted in labiate peppermint herb.The entitled Mentha of Latin plant canadaensis L.Major function is：Dispelling wind and heat, main anemopyretic cold, headache, hot eyes, abscess of throat, dentalgia, skin scabies Itch.

Borneol also known as piece brain, orange slices, L-Borneol, kapur, MEIHUA BINGPIAN, Dipterocarpus pilosus, plum blossom brain, borneol brain, Mei Bing Deng through steam distillation and being recrystallized and obtained by composite family Blumea balsamifera cauline leaf or canella borneol camphor tree branches and leaves.Borneol acrid flavour, Hardship is slightly cold；The thoughts of returning home, liver, lung channel；Delicate fragrance a surname dissipate has the effect of inducing resuscitation of having one's ideas straightened out, heat-clearing dissipates poison, removing nebula, cures mainly pyreticosis height Hot coma, apoplexy coma due to blocking of the respiratory system shies epilepsy, summer-heat and damp blinds clear key, throat deafness, aphtha tooth swells, sore carbuncle infantile malnutrition due to digestive disturbances or intestinalparasites hemorrhoid, red eye, swell pain, screen film hide Eyeball.

Menthol and borneol collective effect, to dissipate inducing resuscitation of having one's ideas straightened out medicine.Menthol is volatile, is not suitable for decocting for a long time, It should be eventually adding when being used in conjunction with other medicinal materials.Borneol is drugs of causing resuscitation by administering aromatic drugs, and active ingredient is volatile when decoction, decocts When should also be eventually adding.

Ginseng, grass-leaved sweetflag, Radix Codonopsis, the stem of noble dendrobium, pearl, menthol, borneol be make medicine, when resuscitation with aromatics, draw all medicines enter through, The drug that all medicines guide drugs to illness station in the side of drawing, second is that harmonizing drug, the i.e. effect of coordinating the drug actions of a prescription, make its resultant force eliminating evil.

In some embodiments, the monarch drug in a prescription, ministerial drug, adjutant and make the composition of medicine that can also be：10 parts of monarch drug in a prescription, ministerial drug 8 Part, makes 3 parts of medicine at 6 parts of adjutant；14 parts of monarch drug in a prescription, 10 parts of adjutant, makes 6 parts of medicine at 12 parts of ministerial drug；11 parts of monarch drug in a prescription, 9 parts of ministerial drug, adjutant 7 Part makes 5 parts of medicine；12 parts of monarch drug in a prescription, 8 parts of adjutant, makes 4 parts of medicine at 10 parts of ministerial drug；13 parts of monarch drug in a prescription, 7 parts of adjutant, makes medicine 5 at 8 parts of ministerial drug Part；14 parts of monarch drug in a prescription, 9 parts of adjutant, makes 3 parts of medicine at 11 parts of ministerial drug；13 parts of monarch drug in a prescription, 6 parts of adjutant, makes 4 parts of medicine at 8 parts of ministerial drug；Monarch drug in a prescription 12 Part, makes 6 parts of medicine at 9 parts of ministerial drug, 7 parts of adjutant；11 parts of monarch drug in a prescription, 7 parts of adjutant, makes 4 parts of medicine at 10 parts of ministerial drug；10 parts of monarch drug in a prescription, ministerial drug 8 Part, 7 parts of adjutant make 5 parts of medicine etc..

Monarch theory is seen earliest《Interior warp》.He Baizhai《Medicine my humble opinion》Cloud：" on the whole curing the disease for medicine is respectively led. Main patient, monarch；The auxiliary person of controlling, minister；With monarch mutually help person instead, assistant；Tying-in and draw the medicine cured the disease as sick institute person, makes ." ZHANG Jie bin《Class is through three products above and below prescription the monarch and his subjects》Meaning：" main patient, the key medicine of verification, therefore the monarch of meaning, monarch person's taste number are few And it is point double, rely based on.The minister of monarch person's meaning is helped, taste number is slightly more and is divided to two slightly gently, so the monarch's that rectifies does not wait till.Ying Chenzhe Meaning makes, and number can come in and go out and be divided to two gentlier, and institute is in case current guide makes.The justice of this then monarch.”

Prescription is made of drug, and drug enhances by orderly compatibility or change its own function, it is adjusted to win partially, Its toxicity is made, the adverse reaction eliminated or slow down it to human body is played and is complemented each other between drug or equal comprehensive functions of opposing each other and yet also complement each other, The pharmaceutical composition of each tool characteristic is set to become an entirety, to play the effect of better prevention and treatment disease.Monarch It is the principles of formulating prescriptions of prescription.

Primary and secondary in the monarch side of explanation in position and treatment of the drug in side cooperates with the antagonism relationship, is that drug is matched 5 basic principle.In general, the monarch drug in a prescription in a prescription is indispensable, and minister, helps, keeps medicine not complete.

A kind of preparation method of herb liquid that alleviating ophthalmic uncomfortable disease, the herb liquid are original with above-mentioned Chinese medicine composition Material, includes the following steps：

(a) Chinese medicine composition except menthol, borneol is soaked in water, it is first then to boil to water and Chinese medicine total volume Stop when the half of beginning water and Chinese medicine total volume, taking liquid is up to first time liquid；

(b) plus water continues to boil, and boils the water and Chinese medicine total volume being added into water and Chinese medicine total volume thus step Stop when 30%, taking liquid is up to second of liquid；

(c) the first time liquid and second of liquid are mixed, then precipitated impurities take supernatant, boil and peppermint is added Piece and borneol to get.

Preferably, in step (a), the dosage of water when being soaked in water is the 42~65 of the Chinese traditional medicine composition amount of substance Times, the soaking time is 18~25min.

The fully expansion of medicinal material moistening can be made by fully impregnating, and be dissolved convenient for effective ingredient when decocting.In some implementations In example, the dosage of water when being soaked in water is that the multiple of the Chinese traditional medicine composition amount of substance can also be 45,50,55,60,62 times Deng result is almost the same within this range.

Preferably, in step (a), described boil turns to be cooked by medium heat again first to boil 35~45min with high heat.

Infusion temperature has a great impact to the precipitation of effective component of chinese medicine, and different endure is selected according to medicament characteristic difference Boil temperature, general inducing diaphoresis, heat-clearing formula should not small fire decoct long, and the savoury nourishing suitable small fire of class medicament is decocted long.Intense fire refers to big fire, the intensity of a fire Anxious, firepower is violent, and temperature rise is fast, a kind of decoction more than moisture evaporation.The application is suitble to the mode being cooked by medium heat after first intense fire, first uses Intense fire, which boils 35~45min, makes each medicinal material pharmacological property discharge as early as possible, reuses the steady infusion of moderate heat.In some embodiments, the use The time that intense fire boils can also be 38min, 40min, 42min etc., and result is almost the same within this range.

It boils to water and Chinese medicine total volume to stop when initial water and the half of Chinese medicine total volume, taking liquid is up to first time medicine Liquid.Stop when adding water to continue to boil, and boiling the 30% of the water and Chinese medicine total volume that are added into water and Chinese medicine total volume thus step, Taking liquid is up to second of liquid.

In step (b), described plus water amount is 45%~55% of the dosage of water described in step (a).

Infusion is divided into twice, and such infusion can endure out 80% of active ingredient or so, and primary endure long cannot replace two Secondary point is endured, so the number decocted medicinal herbs to be advisable twice.Add water when second of infusion again, it is about first time addition to add the amount of water Half.In some embodiments, the amount of described plus water can also be the dosage of water described in step (a) 48%, 50%, 52% etc., result is almost the same within this range.

Preferably, in step (c), the precipitated impurities are to stand 14~18h.

The first time liquid and second of liquid are uniformly mixed, about 14~18h is stood and waits for contamination precipitation, then take Supernatant, boil and be added Herba Menthae slice and borneol to get.In some embodiments, the time of the standing can also be 15h, 16h Deng result is almost the same within this range.

A kind of Chinese medicine preparation patch that ophthalmic uncomfortable disease is effectively relieved, the patch include above-mentioned herb liquid and eye mask paper Patch；The herb liquid is impregnated on the eye mask paper patch.

Preferably, the material of the eye mask paper patch can be the one or more of non-woven fabrics, cotton or silk.

Preferably, the patch further includes protective layer, described to protect the both sides for being placed on the eye mask paper patch.

In some embodiments, Chinese medicine drop can directly be used on eye mask paper patch using preceding.

Eye mask patch made of the herb liquid can be to the eye of eye is dry, eye is puckery, eye is tired under the action of said medicine Labor, itch, the diseases such as redness, muscae volitantes, rainbow conjunctivitis play preferable mitigation.

Compared with prior art, beneficial effects of the present invention are：

(1) using science of TCM formulas as theoretical foundation, using monarch as the principles of formulating prescriptions, very to the selection of prescription Chinese medicine object It is fastidious, select suitable Chinese medicine and by orderly compatibility to enhance the effect of it alleviates eye common uncomfortable diseases.

(2) it needs to consider different medicinal properties during infusion prepares herb liquid, through studying for many years, herb liquid of the present invention Preparation method technical maturity, be very suitable for the Chinese medicine composition of the application.

(3) Chinese medicine preparation patch of the present invention, stablize it is safe, easy to use, be readily produced.

Specific implementation mode

Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will Understand, the following example is merely to illustrate the present invention, and is not construed as limiting the scope of the invention.It is not specified in embodiment specific Condition person carries out according to conventional conditions or manufacturer's recommended conditions.Reagents or instruments used without specified manufacturer is It can be with conventional products that are commercially available.

Embodiment 1

Weigh butterflybush flower 3.4g, climbing groundsel 3.3g, pipewort 3.3g, cassia seed 2g, coptis 2g, chamomile 2g, holy basil 2g, moutan bark 3g, Radix Salviae Miltiorrhizae 3g, ginseng 0.4g, grass-leaved sweetflag 0.4g, Radix Codonopsis 0.4g, stem of noble dendrobium 0.45g, pearl 0.45g, menthol Remaining medicinal material in addition to menthol and borneol is put into stainless-steel pan by 0.45g, borneol 0.45g, adds clear water 1.2L, is impregnated 18min.Then turn to be cooked by medium heat after intense fire boils 35 minutes to water and Chinese medicine total volume when being the half of initial water and Chinese medicine total volume Stop, pouring out in liquid to a clean glass container, this is first time liquid.The clear water for adding 0.6L again continues to be cooked by medium heat, And stop when boiling the 1/3 of the water and Chinese medicine total volume that are added into water and Chinese medicine total volume thus step, liquid is poured out and first Secondary medicinal liquid agitating mixing, stands 14h, waits for contamination precipitation.Liquid after staticly settling is boiled, tripping in menthol and borneol, i.e., Obtain this liquid.By 5g liquids drop in i.e. usable on eye mask paper patch.

Embodiment 2

Weigh butterflybush flower 4.6g, climbing groundsel 4.7g, pipewort 4.7g, cassia seed 3g, coptis 3g, chamomile 3g, holy basil 3g, moutan bark 5g, Radix Salviae Miltiorrhizae 5g, ginseng 0.85g, grass-leaved sweetflag 0.85g, Radix Codonopsis 0.85g, stem of noble dendrobium 0.85g, pearl 0.85g, menthol Remaining medicinal material in addition to menthol and borneol is put into stainless-steel pan by 0.85g, borneol 0.9g, adds clear water 2.2L, is impregnated 18min.Then intense fire, which boils, turns to be cooked by medium heat after forty minutes to water and Chinese medicine total volume when being the half of initial water and Chinese medicine total volume Stop, pouring out in liquid to a clean glass container, this is first time liquid.The clear water for adding 1.1L again continues to be cooked by medium heat, And stop when boiling the 1/3 of the water and Chinese medicine total volume that are added into water and Chinese medicine total volume thus step, liquid is poured out and first Secondary medicinal liquid agitating mixing, stands 15h, waits for contamination precipitation.Liquid after staticly settling is boiled, tripping in menthol and borneol, i.e., Obtain this liquid.By 5g liquids drop in i.e. usable on eye mask paper patch.

Embodiment 3

Weigh butterflybush flower 4g, climbing groundsel 4g, pipewort 4g, cassia seed 2.5g, coptis 2.5g, chamomile 2.5g, holy basil 2.5g, moutan bark 4g, Radix Salviae Miltiorrhizae 4g, ginseng 0.55g, grass-leaved sweetflag 0.55g, Radix Codonopsis 0.55g, stem of noble dendrobium 0.55g, pearl 0.6g, peppermint Remaining medicinal material in addition to menthol and borneol is put into stainless-steel pan by brain 0.6g, borneol 0.6g, adds clear water 2L, is impregnated 18min.Then turn to be cooked by medium heat after intense fire boils 45 minutes to water and Chinese medicine total volume when being the half of initial water and Chinese medicine total volume Stop, pouring out in liquid to a clean glass container, this is first time liquid.The clear water for adding 1L again continues to be cooked by medium heat, and Boil the water and Chinese medicine total volume that are added into water and Chinese medicine total volume thus step 1/3 when stop, liquid pour out with for the first time Medicinal liquid agitating mixes, and stands 18h, waits for contamination precipitation.Liquid after staticly settling is boiled, tripping in menthol and borneol to get This liquid.By 5g liquids drop in i.e. usable on eye mask paper patch.

Embodiment 4

Weigh butterflybush flower 3.6g, climbing groundsel 3.7g, pipewort 3.7g, cassia seed 2.5g, coptis 2.5g, chamomile 2.0g, Holy basil 2.0g, medicinal material is put into stainless-steel pan, adds clear water 1.1L, impregnates 18min.Then intense fire boils turns after forty minutes Fire is boiled to water and Chinese medicine total volume to stop when initial water and the half of Chinese medicine total volume, is poured out liquid to a clean glass and is held In device, this is first time liquid.The clear water for adding 0.6L again continues to be cooked by medium heat, and boils to water and Chinese medicine total volume step thus The water of middle addition and Chinese medicine total volume 1/3 when stop, liquid is poured out to be mixed with first time medicinal liquid agitating, is stood 15h, is waited for impurity Precipitation.Liquid after staticly settling is boiled to get this liquid.By 5g liquids drop in i.e. usable on eye mask paper patch.

Experimental example 1

Influence of the different Traditional Chinese medicine composition formulas to ophthalmic uncomfortable disease remission effect.

Comparative example is set based on embodiment 3, wherein：

Comparative example 1：Without monarch drug in a prescription, i.e. cassia seed 2.5g, coptis 2.5g, chamomile 2.5g, holy basil 2.5g, moutan bark 4g, Radix Salviae Miltiorrhizae 4g, ginseng 0.55g, grass-leaved sweetflag 0.55g, Radix Codonopsis 0.55g, stem of noble dendrobium 0.55g, pearl 0.6g, menthol 0.6g, borneol 0.6g, the water of addition are the water of weight ratio same as Example 3；

Comparative example 2：Without monarch drug in a prescription, ensures ministerial drug, adjutant, the ratio of medicine is made still to be 10：8：4, make foot of building up one's health by taking tonic with ministerial drug adjutant Quality to same as Example 3, weigh cassia seed 3.8g, coptis 3.9g, chamomile 3.8g, holy basil 3.9g, moutan bark 6.2g, Radix Salviae Miltiorrhizae 6.2g, ginseng 0.88g, grass-leaved sweetflag 0.88g, Radix Codonopsis 0.88g, stem of noble dendrobium 0.88g, pearl 0.89g, menthol 0.89g, borneol 0.89g, the water of addition are the water of weight ratio same as Example 3.

Remaining operation is same as Example 3.

Crowd between 4 years old to 75 years old is using having found allergy and bad phenomenon at random, embodiment at 200, wherein It is muscae volitantes patient to have 3, remaining for it is long-term in face of computer, see for a long time TV, drive vehicle, writing crowd, have eye it is dry, Eye is puckery, the symptoms such as eye-blurred, shed tears, itch it is one or more.

Each 5g of liquid in Example 1~4 and comparative example 1~2, drop on the eye mask scraps of paper, be then affixed to subject eye On eyeball, so that eye mask patch is fitted in circumference of eyes completely, removed after 15~20min and record use feeling.

Use feeling and statistics are shown in Table 1.

Influence statistical form of the different Traditional Chinese medicine composition formulas of table 1 to ophthalmic uncomfortable disease remission effect

From table 1 it follows that the Examples 1 to 4 of application scheme has preferable effect for alleviating ophthalmic uncomfortable, It can feel that the bright eyesight of eyes understands using being removed after 15~20min.Wherein about 90% tested crowd indicates that eye is bright Bright salubrious, about 60%~85% indicates to alleviate feeling of fatigue and disease of itching, and 85%~90% experiencer indicates that fuzzy sense weakens, About 6%~11% in addition to refrigerant sense is without other improvement, and three muscae volitantes patients have 2 patients to be improved.

From analysis in embodiment and comparative example result it is found that being included at least in the formula of Examples 1 to 4 has the monarch and his subjects two Side, effect is more close, and better than the formula of other comparative examples, only embodiment 4 is because of no adjutant and the addition for making medicine, Chinese medicine Irritation is larger, and uncomfortable experience is caused to subject.Comparative example 1 is substantially reduced that ministerial drug, effect is not added, and if Quality same as Example 3, i.e. comparative example 2 are complemented to other medicines, effect is risen, but still obviously is inferior to implement Example.It these results suggest that, Chinese medicine composition of the invention setting is reasonable, has obvious effect to alleviating the various uncomfortable diseases of eye, especially It is the setting of ministerial drug, has the effect of that other medicines are incomparable, if being removed effect can substantially reduce.Illustrate the application with Science of TCM formulas is theoretical foundation, and using monarch as the principles of formulating prescriptions, each medicament complements each other, by orderly compatibility to enhance it The effect of alleviating eye common uncomfortable diseases.

Finally it should be noted that：The above embodiments are only used to illustrate the technical solution of the present invention., rather than its limitations；To the greatest extent Present invention has been described in detail with reference to the aforementioned embodiments for pipe, but it will be understood by those of ordinary skill in the art that：Its It still can be with technical scheme described in the above embodiments is modified, either to which part or all technical features Carry out equivalent replacement；And these modifications or replacements, various embodiments of the present invention skill that it does not separate the essence of the corresponding technical solution The range of art scheme.

Claims

1. a kind of Chinese medicine composition for alleviating ophthalmic uncomfortable disease, which is characterized in that the Chinese medicine composition includes：With parts by weight Meter, 10~14 parts of monarch drug in a prescription and 8~12 parts of ministerial drug；

The monarch drug in a prescription is made of butterflybush flower, climbing groundsel, pipewort, the butterflybush flower, climbing groundsel, pipewort mass ratio be 0.8 ~1.2：0.8~1.2：0.8~1.2；

The ministerial drug is made of cassia seed, the coptis, chamomile, holy basil；The cassia seed, the coptis, chamomile, holy basil matter Amount is than being 0.8~1.2：0.8~1.2：0.8~1.2：0.8~1.2.

2. the Chinese medicine composition according to claim 1 for alleviating ophthalmic uncomfortable disease, which is characterized in that the Chinese medicine composition Further include 6~10 parts of adjutant, the adjutant is moutan bark and Radix Salviae Miltiorrhizae；The mass ratio of the moutan bark and Radix Salviae Miltiorrhizae be 0.8~ 1.2：0.8~1.2.

3. the Chinese medicine composition according to claim 1 or 2 for alleviating ophthalmic uncomfortable disease, which is characterized in that the Chinese medicine group The medicine that makes that object further includes 3~6 parts is closed, it is described to make medicine for ginseng, grass-leaved sweetflag, Radix Codonopsis, the stem of noble dendrobium, pearl, menthol, borneol, it is described Ginseng, grass-leaved sweetflag, Radix Codonopsis, the stem of noble dendrobium, pearl, menthol, borneol mass ratio be 0.8~1.2：0.8~1.2：0.8~1.2： 0.8~1.2：0.8~1.2：0.8~1.2：0.8~1.2.

4. it is a kind of alleviate ophthalmic uncomfortable disease herb liquid preparation method, which is characterized in that the herb liquid with claim 1~ 3 any one of them Chinese medicine compositions are prepared by raw material, are included the following steps：

(a) Chinese medicine composition is soaked in water, it is initial water and Chinese medicine total volume then to boil to water and Chinese medicine total volume Stop when half, taking liquid is up to first time liquid；

(b) plus water continues to boil, and when boiling the 30% of the water and Chinese medicine total volume that are added into water and Chinese medicine total volume thus step Stop, taking liquid is up to second of liquid；

(c) the first time liquid and second liquid are mixed, precipitated impurities then take supernatant to get；

If containing Herba Menthae slice and borneol in the Chinese medicine composition, the supernatant obtained in step (c) is boiled, peppermint is added Piece and borneol.

5. the preparation method of the herb liquid according to claim 4 for alleviating ophthalmic uncomfortable disease, which is characterized in that in step (a) in, the dosage of water when being soaked in water is 42~65 times of the Chinese traditional medicine composition amount of substance, the soaking time is 18~ 25min。

6. the preparation method of the herb liquid according to claim 4 for alleviating ophthalmic uncomfortable disease, which is characterized in that in step (a) in, described boil turns to be cooked by medium heat again first to boil 35~45min with high heat.

7. the preparation method of the herb liquid according to claim 4 for alleviating ophthalmic uncomfortable disease, which is characterized in that in step (b) in, described plus water amount is 45%~55% of the dosage of water described in step (a).

8. the preparation method of the herb liquid according to claim 4 for alleviating ophthalmic uncomfortable disease, which is characterized in that in step (c) in, the precipitated impurities are to stand 14h~18h.

9. a kind of Chinese medicine preparation patch that ophthalmic uncomfortable disease is effectively relieved, which is characterized in that the patch include claim 4~ 8 any one of them herb liquids and eye mask paper patch；The herb liquid is impregnated on the eye mask paper patch.

10. the Chinese medicine preparation patch according to claim 9 that ophthalmic uncomfortable disease is effectively relieved, which is characterized in that the eye The material of film paper patch can be the one or more of non-woven fabrics, cotton or silk；