CN108607079A - 平正理肠制剂 - Google Patents

平正理肠制剂 Download PDF

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CN108607079A
CN108607079A CN201611190213.0A CN201611190213A CN108607079A CN 108607079 A CN108607079 A CN 108607079A CN 201611190213 A CN201611190213 A CN 201611190213A CN 108607079 A CN108607079 A CN 108607079A
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董早霞
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
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    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Abstract

本发明公开了一种用于治疗慢性溃疡性结肠炎内服中药制剂，其特征在于，选择的中药原料及重量份分别是：葛根35克、车前子25克、党参25克、木香10克、藿香10克、苏梗10克、干姜9克、苍术10克、白术10克、厚朴10克、陈皮10克、补骨脂12克、炙甘草9克。本发明所选用的原料药材药性效互补，规避了药物之间配伍的相恶、相畏、相杀之选，使药物相须、相使作用显著，具有温补脾肾、理气燥湿的功效。内服治疗慢性溃疡性结肠炎，具有确切疗效。

Description

平正理肠制剂
技术领域
本发明涉及中药领域，具体涉及一种平正理肠制剂，用于治疗慢性溃疡性结肠炎内服中药制剂，具有温补脾肾、理气燥湿的功效。
背景技术
溃疡性结肠炎的最初表现可有许多形式。血性腹泻是最常见的早期症状。其他症状依次有腹痛、便血、体重减轻、里急后重、呕吐等。偶尔主要表现为关节炎，虹膜睫状体炎，肝功能障碍和皮肤病变。发热则相对是一个不常见的征象，在大多数病人中本病表现为慢性、低恶性，在少数病人中呈急性、灾难性暴发的过程。这些病人表现为频繁血性粪便，可多达30次/天，和高热、腹痛。体征与病期和临床表现直接相关，病人往往有体重减轻和面色苍白，在疾病活动期腹部检查时结肠部位常有触痛。可能有急腹症征象伴发热和肠鸣音减少，在急性发作或暴发型病例尤为明显。中毒性巨结肠时可有腹胀、发热和急腹症征象。由于频繁腹泻，肛周皮肤可有擦伤、剥脱。还可发生肛周炎症如肛裂或肛瘘，虽然后者在Crohn病中更为常见。直肠指检感疼痛。皮肤、黏膜、舌、关节和眼部的检查极为重要。
发明内容
本发明涉及中药领域，具体涉及一种用于治疗慢性溃疡性结肠炎内服中药制剂，具有温补脾肾、理气燥湿的功效。内服，可以用于慢性溃疡性结肠炎治疗，具有确切疗效。
为实现上述目的本发明采用了如下的技术方案：本发明所述中药制剂选择的药材及重量份分别是：葛根35克、车前子25克、党参25克、木香10克、藿香10克、苏梗10克、干姜9克、苍术10克、白术10克、厚朴10克、陈皮10克、补骨脂12克、炙甘草9克。
本发明选择的中药原料中：葛根：具有滋身健体、抗衰老、降压、降糖、降脂、增加皮肤弹性、润肤等功效。葛根中所含异黄酮具有滋润皮肤、恢复皮肤弹性的作用，还可以减缓骨骼组织细胞的老化，有助于钙质的吸收，减少骨钙丢失，增加骨密度并阻止骨骼的中空消溶，从而远离骨质疏松。葛根中的活性成分能够预防心脑血管等疾病以及有效缓解更年期综合症，又能延年益寿、增进健康，是中年女性日常保健、提高生活质量的理想选择。最值得推荐的是，女性常吃葛根，可以促使胸部发育增大，这主要就是异黄酮的功劳。化学成分：葛根主要含异黄酮类之葛根素和三萜类葛皂醇等成分。
车前子：性味：甘；淡；性微寒。归经：归肺经；肝经；肾经；膀胱经。功能：清热利尿；渗湿止泻；明目；祛痰。主治：主小便不利；淋浊带下；水肿胀满；暑湿泻痢；目赤障翳；痰热咳喘。
党参：具有补中益气，健脾益肺的功效。用于脾肺虚弱，气短心悸，食少便溏，虚喘咳嗽，内热消渴等。性味归经：性平，味甘、微酸。归脾、肺经。
木香：【功效分类】：理气药；行气药；温里药。【功效】：行气止痛；调中导滞。【主治】：胞胁胀满足；脘腹胀痛；哎吐泄泻；痢疾后重。
藿香：性微温，味辛甘，具有芳香化湿、发表解暑、解表散邪、利湿除风、清热止渴、和胃止呕、快气和中、健胃祛湿等功效。用于治疗头痛发热、风寒感冒、胸闷腹胀、胃寒疼痛、呕吐、泻痢、口臭等症，但阴虚火旺者忌食。藿香有杀菌功能，口含一叶可除口臭，预防传染病，并能用作防腐剂。夏季用藿香煮粥或泡茶饮服，对暑湿重症，脾胃湿阻，脘腹胀满，肢体重困，恶心呕吐有效。
苏梗：性味：辛，温。归经：归肺、脾经。功能主治：理气宽中，止痛，安胎。用于胸膈痞闷，胃脘疼痛，嗳气呕吐，胎动不安。
干姜：【性味、归经】味辛，性热。归脾、胃、心、肺经。【功效】温中散寒，回阳通脉，燥湿消痰，温肺化饮。【主治】脘腹冷痛；呕吐；泄泻，亡阳厥逆；寒饮喘咳；寒湿痹痛。
苍术：入药部位，植物的干燥根茎。性味：味辛、苦，性温。归经、归脾、胃、肝经。功效：燥湿健脾，祛风散寒，明目。主治：用于湿阻中焦，脘腹胀满，泄泻，水肿，脚气痿蹙，风湿痹痛，风寒感冒，夜盲，眼目昏涩。
白术：【性味归经】苦、甘，温。归脾、胃经。功效：健脾益气，燥湿利水，止汗，安胎。用于脾虚食少，腹胀泄泻，痰饮眩悸，水肿，自汗，胎动不安。
厚朴：【性味】：苦；辛；性温【归经】：脾经；胃经；大肠经。【功能】：行气消积；燥湿除满；降逆平喘【主治】：食积气滞；腹胀便秘；湿阻中焦，脘痞吐泻；痰壅气逆；胸满喘咳。
陈皮：陈皮含橙皮甙约8.4％，川陈皮素(nobiletin)约0。15％.另含辛弗林(对羟福林)0.28％-2。54％。【性味】苦、辛，温。【归经】归肺、脾经。【主治功效】：理气健脾，调中，燥湿，化痰。主治脾胃气滞之脘腹胀满或疼痛、消化不良。湿浊阻中之胸闷腹胀、纳呆便溏。痰湿壅肺之咳嗽气喘。用于胸脘胀满，食少吐泻，咳嗽痰多。
补骨脂：补肾助阳；纳气平喘；温脾止泻。主肾阳不足；下元虚冷；腰膝冷痛；阳痿遗精；尿频；遗尿；肾不纳气；虚喘不止；脾肾两虚；大便久泻。
炙甘草：含有甘草甜素、甘草次酸、甘草多糖等多种化学成分，具有抗炎及抗变态反应作用，可调节机体免疫功能，抗肿瘤和止痛作用。因此炙甘草的主要功效是和中缓急，润肺，解毒，调和诸药。常用于脾胃虚弱，倦怠乏力，心动悸，脉结代，可解附子毒。
本发明所选用的原料药材药性效互补，规避了药物之间配伍的相恶、相畏、相杀之选，使药物相须、相使作用显著，具有提高免疫力，温补脾肾、理气燥湿的功效。内服治疗慢性溃疡性结肠炎，具有确切疗效。
利用本发明所述用于治疗慢性溃疡性结肠炎内服中药制剂，通过临床应用，取得了意想不到的满意效果；
本发明药物治疗慢性溃疡性结肠炎临床观察：
1.一般资料
收治门诊患者共30例，其中男15例，女15例，男女之比为1∶1年龄20～30岁3例，31～40岁4例，41～50岁12例，50岁以上11例。
2.具体实施病例如下：白XX，女，49岁，1990年5月21日初诊。自1989年11月起腹痛，里急后重，下痢便血，日3-4次，甚则6次，某医院诊断为慢性溃疡性结肠炎，屡治不效。1990年5月20日来我处诊治，届时已便血半年有余。患者面黄肢冷，两胁胀痛，脘闷纳呆，心悸时烦，夜寐不宁，舌质淡润，脉象弦细而濡、此乃脾肾虚寒，肝郁气滞，横克脾土，脾不能藏，故便血不止。随投以本发明方剂6剂，日服1剂，早晚分2次温服。为一疗程做汤剂内服治疗，日后再诊时，便血止，下痢减轻，日1-2行，脘胁胀痛大减，纳食转好，夜以能寐。继服12个疗程，诸症皆除。嘱咐其，继续治疗一疗程巩固疗效。服数剂即愈。
具体实施方式
所述用于治疗慢性溃疡性结肠炎内服中药制剂，其特征在于，选择的中药原料及重量份分别是：葛根35克、车前子25克、党参25克、木香10克、藿香10克、苏梗10克、干姜9克、苍术10克、白术10克、厚朴10克、陈皮10克、补骨脂12克、炙甘草9克；
制备方法：葛根35克、车前子25克、党参25克、木香10克、藿香10克、苏梗10克、干姜9克、苍术10克、白术10克、厚朴10克、陈皮10克、补骨脂12克、炙甘草9克；分别制成饮片，经过高压锅蒸煮杀菌50-70分钟，晾干，获得无菌原材料，进行密封包装，获得商品中药制剂饮品。

Claims (2)

1.用于治疗慢性溃疡性结肠炎内服中药制剂，其特征在于，选择的中药原料及重量份分别是：葛根35克、车前子25克、党参25克、木香10克、藿香10克、苏梗10克、干姜9克、苍术10克、白术10克、厚朴10克、陈皮10克、补骨脂12克、炙甘草9克。
2.根据权利要求1所述的治疗慢性溃疡性结肠炎内服中药制剂，其特征在于：其制备方法为以下步骤：
步骤一：称取原料药材：葛根35克、车前子25克、党参25克、木香10克、藿香10克、苏梗10克、干姜9克、苍术10克、白术10克、厚朴10克、陈皮1O克、补骨脂12克、炙甘草9克；
步骤二：将所获的饮片，经过高压锅蒸煮杀菌50-70分钟，晾干，获得无菌原材料；
步骤三：将所获的无菌原材料，进行密封包装，获得商品中药制剂饮品。
CN201611190213.0A 2016-12-12 2016-12-12 平正理肠制剂 Pending CN108607079A (zh)

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