CN108578728A - Blood-plasma virus killing instrument - Google Patents
Blood-plasma virus killing instrument Download PDFInfo
- Publication number
- CN108578728A CN108578728A CN201810368896.7A CN201810368896A CN108578728A CN 108578728 A CN108578728 A CN 108578728A CN 201810368896 A CN201810368896 A CN 201810368896A CN 108578728 A CN108578728 A CN 108578728A
- Authority
- CN
- China
- Prior art keywords
- blood
- virus killing
- shell
- killing instrument
- plasma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000002381 plasma Anatomy 0.000 title claims abstract description 58
- 241000700605 Viruses Species 0.000 title claims abstract description 47
- 239000011324 bead Substances 0.000 claims abstract description 27
- 230000002779 inactivation Effects 0.000 claims abstract description 25
- 239000011159 matrix material Substances 0.000 claims abstract description 9
- 238000001816 cooling Methods 0.000 claims description 11
- 239000012780 transparent material Substances 0.000 claims description 3
- 239000004744 fabric Substances 0.000 claims 1
- 230000000415 inactivating effect Effects 0.000 abstract description 11
- 239000003504 photosensitizing agent Substances 0.000 abstract description 9
- 230000000694 effects Effects 0.000 abstract description 7
- 230000000638 stimulation Effects 0.000 abstract description 4
- 238000000034 method Methods 0.000 description 9
- 241000725303 Human immunodeficiency virus Species 0.000 description 6
- 238000002679 ablation Methods 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 3
- 238000005286 illumination Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 230000009849 deactivation Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000017525 heat dissipation Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0029—Radiation
- A61L2/0058—Infrared radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0029—Radiation
- A61L2/0076—Radiation using a photocatalyst or photosensitiser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/22—Blood or products thereof
Abstract
The invention discloses a kind of blood-plasma virus killing instrument, including shell, inactivation cabin and luminescent screen；The inactivation cabin can be passed in and out the shell by the side of the shell, and have supporting plate, and the supporting plate has the loading surface for carrying blood plasma；The luminescent screen is fixed on the enclosure interior, and opposite with the loading surface；The side of the luminescent screen towards the supporting plate is provided with the LED matrix being made of multiple LED lamp beads.The blood-plasma virus killing instrument that the embodiment of the present invention is provided has high stimulation effect to photosensitizer, to greatly improve inactivating efficacy.
Description
Technical field
The present embodiments relate to field of medical technology more particularly to a kind of blood-plasma virus killing instrument.
Background technology
AIDS virus is widely present in the blood plasma of human body, currently, is either infected from prevention because of blood transfusion,
Or vaccine is prepared by the virus in blood plasma, is required to fully inactivate the virus in blood plasma.
Inactivation of virus refers to the side killed virus with physically or chemically means, but do not damage their internal useful antigens
Method.And physical deactivation method and chemical ablation method can respectively be subdivided into various ways, such as physical deactivation method can
Including ultrasonic wave inactivation, ultraviolet inactivation, ray inactivation, high pressure inactivation etc..Chemical ablation method may include photoinactivation, enzyme
Chemical ablation etc..Each ablation method has the scope of application of its own, it is impossible to be played to all virus, bacterium identical
Effect.Therefore, inactivation mode is reasonably selected to be very important.By many experiments, it has been found that photoinactivation for
The inactivating efficacy of inhibition of HIV is better than other ablation methods.
Photoinactivation method refers to that photosensitizer is added in the blood plasma for carrying AIDS virus, then carries out light to blood plasma
According to making light excite photosensitizer, and the method for inactivation of viruses.Therefore, photosensitizer is to parameters poles such as wavelength, the intensities of illumination of light
For sensitivity, the inactivating efficacy of AIDS virus can be largely influenced.
However, blood-plasma virus killing equipment in the related technology, which usually relies on incandescent lamp, carries out light irradiation, due to white heat
The light that lamp is sent out is continuous spectrum, therefore limited for the stimulation effect of photosensitizer, bad so as to cause inactivating efficacy.
Invention content
The embodiment of the present invention provides a kind of blood-plasma virus killing instrument, to solve the problems, such as that inactivating efficacy is bad.
The embodiment of the present invention uses following technical proposals：
The embodiment of the present invention provides a kind of blood-plasma virus killing instrument, including shell, inactivation cabin and luminescent screen；
The inactivation cabin can be passed in and out the shell by the side of the shell, and have supporting plate, and the supporting plate, which has, to be used
In the loading surface of carrying blood plasma；
The luminescent screen is fixed on the enclosure interior, and opposite with the loading surface；
The side of the luminescent screen towards the supporting plate is provided with the LED matrix being made of multiple LED lamp beads.
Preferably, in blood-plasma virus killing instrument above-mentioned, the supporting plate manufactures for transparent material, the quantity of the luminescent screen
It is two, is located at the both sides up and down of the supporting plate.
Preferably, further include cooling fin in blood-plasma virus killing instrument above-mentioned, the cooling fin is located in the shell
Portion, and the cooling fin covers the side that the luminescent screen deviates from the supporting plate, and the position of the cooling fin is corresponded on the shell
It installs and is equipped with heat emission hole.
Preferably, further include controller and operation panel in blood-plasma virus killing instrument above-mentioned, the controller is located at
The enclosure interior, and being communicated to connect with the luminescent screen, the operation panel is arranged on the surface of the shell, and with it is described
Controller communicates to connect.
Preferably, further include printer, the printer is laid in the shell in blood-plasma virus killing instrument above-mentioned
Inside, and exposed by the shell, the printer is communicated to connect with the controller.
Preferably, further include alarm, the alarm is arranged in the shell in blood-plasma virus killing instrument above-mentioned
Surface.
Preferably, in blood-plasma virus killing instrument above-mentioned, between the two neighboring LED lamp bead between be divided into 15-16mm.
Preferably, in blood-plasma virus killing instrument above-mentioned, the light angle of emergence of the LED lamp bead is 120 °.
Preferably, in blood-plasma virus killing instrument above-mentioned, the spacing between the LED lamp bead and the loading surface is
50mm。
Preferably, in blood-plasma virus killing instrument above-mentioned, the wavelength of light that each LED lamp bead is sent out is 610-
650nm。
Above-mentioned at least one technical solution used in the embodiment of the present invention can reach following advantageous effect：
Light source is used as by the LED matrix being made of LED lamp bead in blood-plasma virus killing instrument disclosed by the embodiments of the present invention,
Since LED lamp bead is monochromatic source, the irradiation optical wavelength range launched is concentrated, therefore has high excitation to photosensitizer
Effect, to greatly improve inactivating efficacy.
Description of the drawings
Fig. 1 is the external structure schematic diagram of blood-plasma virus killing instrument disclosed by the embodiments of the present invention；
Fig. 2 is the interior section structural schematic diagram of blood-plasma virus killing instrument disclosed by the embodiments of the present invention；
Fig. 3 is the structural schematic diagram of luminescent screen disclosed by the embodiments of the present invention；
Fig. 4 is the illumination range schematic diagram of LED lamp bead disclosed by the embodiments of the present invention.
Reference sign：
10- shells, 100- heat emission holes, 11- inactivations cabin, 110- supporting plates, 12- luminescent screens, 120-LED lamp beads, 13- heat dissipations
Piece, 14- operation panels, 15- printers, 16- alarms, the electrical power supply of 17- constant currents.
Specific implementation mode
To make the object, technical solutions and advantages of the present invention clearer, below in conjunction with the specific embodiment of the invention and
Technical solution of the present invention is clearly and completely described in corresponding attached drawing.Obviously, described embodiment is only the present invention one
Section Example, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art are not doing
Go out the every other embodiment obtained under the premise of creative work, shall fall within the protection scope of the present invention.
The technical solution provided below in conjunction with attached drawing, each embodiment that the present invention will be described in detail.
The embodiment of the invention discloses a kind of blood-plasma virus killing instrument, as shown in Figures 1 to 4, blood-plasma virus killing instrument
Critical piece includes shell 10, inactivation cabin 11 and luminescent screen 12.In addition to this, blood-plasma virus killing instrument may also include cooling fin
13, the components such as controller (not shown), operation panel 14, printer 15, alarm 16 and electrical power supply of constant current 17.
Shell 10 be blood-plasma virus killing instrument support and protection structure, other components be respectively positioned on shell 10 inside or
Person's appearance.Specifically, the side of shell 10 is provided with opening (being label in figure), and inactivation cabin 11 can pass in and out shell by the opening
10, inactivating has supporting plate 110 on cabin 11, and the upper surface of supporting plate 110 is the loading surface (being label in figure) for carrying blood plasma.Hair
Tabula rasa 12 is fixed on inside shell 10, and opposite with loading surface, is provided with by multiple in the side of luminescent screen 12 towards supporting plate 110
The LED matrix that LED lamp bead 120 forms.
When carrying out inactivation operation, inactivation cabin 11 is extracted out by opening, the collecting bag for filling blood plasma is placed on supporting plate 110
On loading surface, inactivation cabin 11 is pushed into inside shell 10 later.Luminescent screen 12 is opened, makes LED matrix towards loading surface and puts
The blood plasma set on loading surface sends out irradiation light, to complete the inactivation of blood plasma.Since LED lamp bead 120 is monochromatic source, sent out
The irradiation optical wavelength range of injection is concentrated, therefore has high stimulation effect to photosensitizer, to greatly improve inactivating efficacy.
AIDS virus and photosensitizer can be uniformly distributed substantially in collecting bag, but since the blood plasma in collecting bag has
Certain thickness, therefore irradiate to the light of blood plasma and can gradually weaken with the degree for stretching into blood plasma from collecting bag side, to
The part far from 12 side of luminescent screen in plasma bags may be caused to be unable to fully inactivate.
In order to keep inactivation more abundant, as shown in Fig. 2, the both sides up and down in the present embodiment in supporting plate 110 are respectively set one
A luminescent screen 12, while supporting plate 110 being manufactured using transparent material.In this way, the blood plasma being placed on loading surface can simultaneously by
To the irradiation of upper and lower both direction, keep inactivation more abundant.The light that LED lamp bead 120 is sent out is right within the scope of 610-650nm
The best results of the inactivation of AIDS virus are more recommended using the LED lamp bead 120 that can send out 630nm light.
Exposure intensity will ensure inactivating efficacy also to inactivating efficacy important, just need LED matrix can
Have enough exposure intensities.As shown in Figure 3 and Figure 4, on the basis of the LED lamp bead 120 of current general size, LED lamp bead 120
Light angle of emergence be preferably kept in 120 ° or so, the interval in LED matrix between two adjacent LEDs lamp bead 120 will be maintained at
Within the scope of 15-16mm, and the spacing between LED lamp bead and loading surface may remain in 50mm or so.These measures can ensure
The intensity of illumination that loading surface is received can reach 40000lx.Wherein, the LED lamp bead 120 positioned at 110 downside of supporting plate is penetrated
The light gone out can arrive at loading surface due to needing across supporting plate 110, and the thickness for considering supporting plate 110 is needed when calculating.
LED lamp bead 120 also will produce certain heat when emitting beam, if this partial heat conducts not in time
In the service life that LED lamp bead 120 can not only be influenced, it will also result in security risk.Therefore, in the inside of shell 10, setting dissipates the present embodiment
Backing 13 come cover luminescent screen 12 deviate from supporting plate 110 side, correspond on the housing 10 cooling fin 13 position be additionally provided with it is scattered
Hot hole 100, the heat that LED lamp bead 120 is dissipated can be transferred to cooling fin 13 rapidly by luminescent screen 12, and finally by radiating
Hole 100 is transferred to outside shell 10.In order to improve radiating rate, the good material of the heat conductivilitys such as aluminum substrate may be used in luminescent screen
Matter.
In order to allow users to facilitate the unlatching of control LED matrix and duration time, or control or monitoring blood plasma
The working condition of other components in virus inactivation instrument, the blood-plasma virus killing instrument in the present embodiment are provided with controller and operation
Panel 14.Wherein, controller is located inside shell 10, and is communicated to connect with luminescent screen 12, and operation panel is arranged in shell 10
Surface, and communicated to connect with controller.Certainly, controller can also be communicated to connect with other components or sensor, to send out control
Signal or receiving device parameter information processed.For example, the embodiment of the present invention can also lay printer 15 in the inside of shell 10, beat
Print machine 15 is exposed by the surface of shell 10, and at this time for the ease of controlling printer 15, controller just needs to communicate with printer 15
Connection, in this way, can directly control printer 15 by operation interface 14 prints material requested, for patient or medical worker
It uses.
This point is even more important for portable blood-plasma virus killing instrument, since portable blood-plasma virus killing instrument is frequent
Need in the wild, the conditions such as disaster area it is relatively incomplete area it is interim use, therefore be difficult to be equipped with independent printing device, and lead to
The mode for crossing the integrated printer 15 in blood-plasma virus killing instrument then can be good at solving the problems, such as this.
In addition to this, can also alarm 16 be set on the surface of shell 10.Alarm 16 can be used for reminding operating personnel
Inactivation is completed, or prompt equipment fault, the excessively high abnormal conditions of temperature.Sound, optics or other may be used in prompting mode
The mode that human body can receive.
If above-mentioned component can not directly use alternating current, the blood-plasma virus killing instrument in the present embodiment that constant current can also be arranged
Electrical power supply 17 is powered, and the electrical power supply of the constant current 17 is also disposed in shell 10, and when being worked due to the electrical power supply 17 of constant current
Also it will produce heat, therefore can some heat emission holes can also be set in the position of the electrical power supply of corresponding constant current 17.
The blood-plasma virus killing instrument that the embodiment of the present invention is provided has high stimulation effect to photosensitizer, to substantially
Improve inactivating efficacy.
Emphasis describes the difference between each embodiment in foregoing embodiments of the present invention, different between each embodiment
As long as optimization feature non-contradiction, can combine to form more preferably embodiment, it is contemplated that style of writing is succinct, then no longer superfluous at this
It states.
It these are only the embodiment of the present invention, be not intended to restrict the invention.To those skilled in the art,
The invention may be variously modified and varied.It is all within spirit and principles of the present invention made by any modification, equivalent replacement,
Improve etc., it should be included within scope of the presently claimed invention.
Claims (10)
1. a kind of blood-plasma virus killing instrument, which is characterized in that including shell, inactivation cabin and luminescent screen；
The inactivation cabin can be passed in and out the shell by the side of the shell, and have supporting plate, and the supporting plate has for holding
Carry the loading surface of blood plasma；
The luminescent screen is fixed on the enclosure interior, and opposite with the loading surface；
The side of the luminescent screen towards the supporting plate is provided with the LED matrix being made of multiple LED lamp beads.
2. blood-plasma virus killing instrument according to claim 1, which is characterized in that the supporting plate manufactures for transparent material, institute
The quantity for stating luminescent screen is two, is located at the both sides up and down of the supporting plate.
3. blood-plasma virus killing instrument according to claim 1 or 2, which is characterized in that further include cooling fin, the cooling fin
Positioned at the enclosure interior, and the cooling fin covers the side that the luminescent screen deviates from the supporting plate, is corresponded on the shell
The position of the cooling fin is provided with heat emission hole.
4. blood-plasma virus killing instrument according to claim 1 or 2, which is characterized in that further include controller and operating surface
Plate, the controller is located at the enclosure interior, and is communicated to connect with the luminescent screen, and the operation panel is arranged in the shell
The surface of body, and communicated to connect with the controller.
5. blood-plasma virus killing instrument according to claim 4, which is characterized in that further include printer, the printer cloth
It is located at the inside of the shell, and is exposed by the shell, the printer is communicated to connect with the controller.
6. blood-plasma virus killing instrument according to claim 1 or 2, which is characterized in that further include alarm, the alarm
It is arranged on the surface of the shell.
7. blood-plasma virus killing instrument according to claim 1 or 2, which is characterized in that between the two neighboring LED lamp bead
Between be divided into 15-16mm.
8. blood-plasma virus killing instrument according to claim 7, which is characterized in that the light angle of emergence of the LED lamp bead is
120°。
9. blood-plasma virus killing instrument according to claim 7, which is characterized in that the LED lamp bead and the loading surface it
Between spacing be 50mm.
10. blood-plasma virus killing instrument according to claim 1 or 2, which is characterized in that each LED lamp bead is sent out
Wavelength of light be 610-650nm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810368896.7A CN108578728A (en) | 2018-04-23 | 2018-04-23 | Blood-plasma virus killing instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810368896.7A CN108578728A (en) | 2018-04-23 | 2018-04-23 | Blood-plasma virus killing instrument |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108578728A true CN108578728A (en) | 2018-09-28 |
Family
ID=63614121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810368896.7A Pending CN108578728A (en) | 2018-04-23 | 2018-04-23 | Blood-plasma virus killing instrument |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108578728A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110124140A (en) * | 2019-05-24 | 2019-08-16 | 博心(北京)生物技术开发有限公司 | AIDS therapeutic equipment |
| CN110974984A (en) * | 2019-12-03 | 2020-04-10 | 中国人民解放军总医院第三医学中心 | Inactivation device and inactivation method for riboflavin photochemical blood product |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2497791Y (en) * | 2001-09-03 | 2002-07-03 | 中国人民解放军军事医学科学院野战输血研究所 | Plasma virus inactivator |
| CN102458485A (en) * | 2009-04-21 | 2012-05-16 | 肯尼思·卡姆帕格纳 | Portable antimicrobial ultra violet sterilizer |
| CN203017432U (en) * | 2013-01-21 | 2013-06-26 | 中国人民解放军总医院 | Flow type blood plasma virus inactivation equipment |
| CN205322836U (en) * | 2016-02-02 | 2016-06-22 | 汪相伯 | Blood products treatment facility based on riboflavin photochemistry method |
-
2018
- 2018-04-23 CN CN201810368896.7A patent/CN108578728A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2497791Y (en) * | 2001-09-03 | 2002-07-03 | 中国人民解放军军事医学科学院野战输血研究所 | Plasma virus inactivator |
| CN102458485A (en) * | 2009-04-21 | 2012-05-16 | 肯尼思·卡姆帕格纳 | Portable antimicrobial ultra violet sterilizer |
| CN203017432U (en) * | 2013-01-21 | 2013-06-26 | 中国人民解放军总医院 | Flow type blood plasma virus inactivation equipment |
| CN205322836U (en) * | 2016-02-02 | 2016-06-22 | 汪相伯 | Blood products treatment facility based on riboflavin photochemistry method |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110124140A (en) * | 2019-05-24 | 2019-08-16 | 博心(北京)生物技术开发有限公司 | AIDS therapeutic equipment |
| CN110974984A (en) * | 2019-12-03 | 2020-04-10 | 中国人民解放军总医院第三医学中心 | Inactivation device and inactivation method for riboflavin photochemical blood product |
| CN110974984B (en) * | 2019-12-03 | 2021-10-12 | 中国人民解放军总医院第三医学中心 | Inactivation method of riboflavin photochemical blood product |
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Application publication date: 20180928 |
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