CN108578577A - 一种治疗糖尿病的药物及其制备方法 - Google Patents

一种治疗糖尿病的药物及其制备方法 Download PDF

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CN108578577A
CN108578577A CN201810805997.6A CN201810805997A CN108578577A CN 108578577 A CN108578577 A CN 108578577A CN 201810805997 A CN201810805997 A CN 201810805997A CN 108578577 A CN108578577 A CN 108578577A
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朱德胜
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Abstract

本发明公开了一种治疗糖尿病的药物及其制备方法，包括下述重量份的原料：葛根55‑65份、板蓝根25‑35份、山药55‑65份、柴胡25‑35份、生地25‑35份、猪苓25‑35份、苦参55‑65份、银花35‑45份、绿豆28‑32份、丹参18‑22份、玉竹18‑22份、黄芪28‑32份、红花14‑16份、首乌8‑12份、熟地8‑12份、太子参8‑12份、当归8‑12份、仙灵脾8‑12份、菟丝子14‑16份、川芎14‑16份、桔梗14‑16份、白头翁45‑55份。其制备方法是将所有原料药，加总质量7‑9倍水，武火煮沸后，文火继续煎煮25‑35min，取水煎液；将药渣加总质量5‑7倍水，武火煮沸后，文火继续煎煮20‑30min，合并两次水煎液，混匀即得。能有效降低血糖，治疗糖尿病。其起效快、疗效好，无毒副作用，且用药方便快捷。临床治疗病例18例，总有效率88.9%。

Description

一种治疗糖尿病的药物及其制备方法
技术领域
本发明属于中药技术领域，具体来说涉及一种治疗糖尿病的药物，同时还涉及其制备方法。
背景技术
糖尿病（diabetes mellitus）是一组以高血糖为特征的代谢性疾病。高血糖则是由于胰岛素分泌缺陷或其生物作用受损，或两者兼有引起。糖尿病时长期存在的高血糖，导致各种组织，特别是眼、肾、心脏、血管、神经的慢性损害、功能障碍。糖尿病主要病因有两个方面：1）遗传因素：1型或2型糖尿病均存在明显的遗传异质性。糖尿病存在家族发病倾向，1/4～1/2患者有糖尿病家族史。临床上至少有60种以上的遗传综合征可伴有糖尿病。1型糖尿病有多个DNA位点参与发病，其中以HLA抗原基因中DQ位点多态性关系最为密切。在2型糖尿病已发现多种明确的基因突变，如胰岛素基因、胰岛素受体基因、葡萄糖激酶基因、线粒体基因等。2）环境因素：进食过多，体力活动减少导致的肥胖是2型糖尿病最主要的环境因素，使具有2型糖尿病遗传易感性的个体容易发病。1型糖尿病患者存在免疫系统异常，在某些病毒如柯萨奇病毒，风疹病毒，腮腺病毒等感染后导致自身免疫反应，破坏胰岛素β细胞。主要症状:多饮、多尿、多食和消瘦,严重高血糖时出现典型的“三多一少”症状，多见于1型糖尿病。发生酮症或酮症酸中毒时“三多一少”症状更为明显。疲乏无力，肥胖:多见于2型糖尿病。2型糖尿病发病前常有肥胖，若得不到及时诊断，体重会逐渐下降。
目前临床上治疗糖尿病，选用服用西药治疗糖尿病或者注射胰岛素来治疗糖尿病，虽然能对病情产生一定的控制作用，但大都副作用大，且容易产生药物依赖性强，患者需终身服药，而且胰岛素制剂价格昂贵。中医治疗糖尿病注重整体调控，降糖作用温和、稳定，对糖尿病慢性并发症的防治疗效显著。目前市场上所使用的中药也种类繁多，但效果却参差不齐，不胜理想。
发明内容
本发明的目的在于提供一种起效快、疗效好、无毒副作用的治疗糖尿病的药物。
本发明的另一目的在于提供该药物的制备方法。
本发明的一种治疗糖尿病的药物，包括下述重量份的原料：
葛根55-65份、板蓝根25-35份、山药55-65份、柴胡25-35份、生地25-35份、猪苓25-35份、苦参55-65份、银花35-45份、绿豆28-32份、丹参18-22份、玉竹18-22份、黄芪28-32份、红花14-16份、首乌8-12份、熟地8-12份、太子参8-12份、当归8-12份、仙灵脾8-12份、菟丝子14-16份、川芎14-16份、桔梗14-16份、白头翁45-55份。
上述的一种治疗糖尿病的药物，优选各原料重量份如下：
葛根60份、板蓝根30份、山药60份、柴胡30份、生地30份、猪苓30份、苦参60份、银花40份、绿豆30份、丹参20份、玉竹20份、黄芪30份、红花15份、首乌10份、熟地10份、太子参10份、当归10份、仙灵脾10份、菟丝子15份、川芎15份、桔梗15份、白头翁50份。
上述的一种治疗糖尿病的药物，其制备方法包括如下步骤：
（1）筛选原料药，按重量份取样；
（2）将所有原料药，加总质量7-9倍水，武火煮沸后，文火继续煎煮25-35min，取水煎液；将药渣加总质量5-7倍水，武火煮沸后，文火继续煎煮20-30min，合并两次水煎液，混匀即得。
本发明的药物与现有技术相比，具有明显的优点和效果，由以上技术方案可知：本发明选用葛根、板蓝根、山药、柴胡、生地、猪苓、苦参、银花、绿豆、丹参、玉竹、黄芪、红花、首乌、熟地、太子参、当归、仙灵脾、菟丝子、川芎、桔梗、、白头翁为原料，通过各药物的协同作用发挥生津止渴、清热解毒、健脾化湿之功效。能有效降低血糖，治疗糖尿病。其起效快、疗效好，无毒副作用，且用药方便快捷。临床治疗病例18例，总有效率88.9%。
具体实施方式
以下通过试验例来进一步阐述本发明所述药物的有益效果。
试验例：本发明药物的临床观察
1、病例选择
治疗病例18例，其中：年龄40-70岁，男12例，女6例。
2、疾病诊断标准
《中医病症诊断疗效标准》。
3、治疗方法：
口服本发明实施例所制备的药物，每日三次，三天服一剂，饭后服用，服药期间忌酒，牛、羊肉，少喝茶，多锻炼。1个月为1个疗程，连服效果好，1-4个疗程即可。
4、疗效判定标准
显效：全部症状基本消除或主要症状消除。
有效：主要症状基本消除或明显改善。
无效：各种症状及体征无改变。
5、治疗结果：
全部18例患者使用本发明药物，其中显效15例，有效1例，无效2例，总有效率88.9%。
通过以下实施例来阐明本药物的制备方法。
实施例1
一种治疗糖尿病的药物的制备方法，包括如下步骤：
（1）筛选原料药，称取葛根55g、板蓝根35g、山药55g、柴胡35g、生地25g、猪苓35g、苦参55g、银花45g、绿豆28g、丹参22g、玉竹18g、黄芪32g、红花14g、首乌12g、熟地8g、太子参12g、当归8g、仙灵脾12g、菟丝子14g、川芎16g、桔梗14g、白头翁55g；
（2）将所有原料药，加总质量9倍水，武火煮沸后，文火继续煎煮35min，取水煎液；将药渣加总质量5倍水，武火煮沸后，文火继续煎煮20min，合并两次水煎液，混匀即得。
实施例2
一种治疗糖尿病的药物的制备方法，包括如下步骤：
（1）筛选原料药，称取葛根60g、板蓝根30g、山药60g、柴胡30g、生地30g、猪苓30g、苦参60g、银花40g、绿豆30g、丹参20g、玉竹20g、黄芪30g、红花15g、首乌10g、熟地10g、太子参10g、当归10g、仙灵脾10g、菟丝子15g、川芎15g、桔梗15g、白头翁50g；
（2）将所有原料药，加总质量8倍水，武火煮沸后，文火继续煎煮30min，取水煎液；将药渣加总质量6倍水，武火煮沸后，文火继续煎煮25min，合并两次水煎液，混匀即得。
实施例3
一种治疗糖尿病的药物的制备方法，包括如下步骤：
（1）筛选原料药，称取葛根65g、板蓝根25g、山药65g、柴胡25g、生地35g、猪苓25g、苦参65g、银花35g、绿豆32g、丹参18g、玉竹22g、黄芪28g、红花16g、首乌8g、熟地12g、太子参8g、当归12g、仙灵脾8g、菟丝子16g、川芎14g、桔梗16g、白头翁45g；
（2）将所有原料药，加总质量7倍水，武火煮沸后，文火继续煎煮25min，取水煎液；将药渣加总质量7倍水，武火煮沸后，文火继续煎煮30min，合并两次水煎液，混匀即得。
以上所述，仅是本发明的较佳实施例而已，并非对本发明作任何形式上的限制，任何未脱离本发明技术方案内容，依据本发明的技术实质对以上实施例所作的任何简单修改、等同变化与修饰，均仍属于本发明技术方案的范围内。

Claims (3)

1.一种治疗糖尿病的药物，包括下述重量份的原料：
葛根55-65份、板蓝根25-35份、山药55-65份、柴胡25-35份、生地25-35份、猪苓25-35份、苦参55-65份、银花35-45份、绿豆28-32份、丹参18-22份、玉竹18-22份、黄芪28-32份、红花14-16份、首乌8-12份、熟地8-12份、太子参8-12份、当归8-12份、仙灵脾8-12份、菟丝子14-16份、川芎14-16份、桔梗14-16份、白头翁45-55份。
2.如权利要求1所述一种治疗糖尿病的药物，包括下述重量份的原料：
葛根60份、板蓝根30份、山药60份、柴胡30份、生地30份、猪苓30份、苦参60份、银花40份、绿豆30份、丹参20份、玉竹20份、黄芪30份、红花15份、首乌10份、熟地10份、太子参10份、当归10份、仙灵脾10份、菟丝子15份、川芎15份、桔梗15份、白头翁50份。
3.如权利要求1或2所述的一种治疗糖尿病的药物，其制备方法包括如下步骤：
（1）筛选原料药，按重量份取样；
（2）将所有原料药，加总质量7-9倍水，武火煮沸后，文火继续煎煮25-35min，取水煎液；将药渣加总质量5-7倍水，武火煮沸后，文火继续煎煮20-30min，合并两次水煎液，混匀即得。
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