CN108464814B - Anti-drop experimental animals is with wearable eye stimulation device - Google Patents
Anti-drop experimental animals is with wearable eye stimulation device Download PDFInfo
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- CN108464814B CN108464814B CN201810161113.8A CN201810161113A CN108464814B CN 108464814 B CN108464814 B CN 108464814B CN 201810161113 A CN201810161113 A CN 201810161113A CN 108464814 B CN108464814 B CN 108464814B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/40—Detecting, measuring or recording for evaluating the nervous system
- A61B5/4058—Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
- A61B5/4064—Evaluating the brain
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6802—Sensor mounted on worn items
Abstract
The invention relates to an anti-drop wearable eye stimulation device for experimental animals, which comprises a main body, a first fixing knob, a pulse generator, a current controller, a copper net and an input line joint, wherein eyes are positioned at the inner side of the main body, a skull block is fixed in the main body, the copper net is arranged at the top end of the skull block, a fixing tripod is installed at the top of the copper net, a first bolt penetrates through the top end of the right side of the fixing tripod, a connecting fixing seat is installed at the top of the fixing tripod, a second bolt penetrates through the inner side of the fixing tripod, a screw hole is formed in the top end of the connecting fixing seat, and a second fixing rod penetrates through the top of the screw hole. The invention has the beneficial effects that: this wearable menstruation eye stimulation device for anti-drop experimental animal through being provided with the main part, and the area of the inboard skull piece of main part is greater than the area of copper mesh, under the combined action of copper mesh and fixed horizontal pole, can be to the embedding of experimental animal's intracranial administration pipe, electrode etc..
Description
Technical Field
The invention relates to the technical field of eye stimulation of experimental animals, in particular to an anti-drop wearable eye stimulation device for experimental animals.
Background
With the development of science and technology and the progress of the social era, the realization of higher nerve function depends on the release activity of neurons, the release activity of neuron groups in different brain areas is represented as specific frequency oscillation, the oscillation can be changed by the input of external sensory stimulation, and the execution of higher brain functions is further influenced, and the external sensory stimulation needs to be operated by an eye stimulation device.
The existing ocular stimulation device has the advantages that the position of a luminous source is fixed in the using process, the intensity of the luminous source is insufficient, inconvenience is brought to the ocular stimulation work of free-living animals, the weight of the device is large, the size is large, and the weight of the animal cannot be loaded.
Disclosure of Invention
The invention aims to provide an anti-drop wearable eye stimulation device for experimental animals, and aims to solve the problems that the existing eye stimulation device in the background art is inconvenient for eye stimulation of free living animals due to the fact that a light source is fixed in position and insufficient in intensity in the using process, and the eye stimulation device is heavy in weight and large in size, so that the animals cannot bear weight.
In order to achieve the purpose, the invention provides the following technical scheme: a wearable meridian and gaze stimulation device for an anti-drop experimental animal comprises a main body, a first fixing knob, a pulse generator, a current controller, a copper net and an input line connector, wherein during experiment, eyes are positioned at the inner side of the main body, a skull block is fixed inside the main body, the copper net is arranged at the top end of the skull block, a fixing tripod is installed at the top of the copper net, a first bolt penetrates through the top end of the right side of the fixing tripod, a connecting fixing seat is installed at the top of the fixing tripod, a second bolt penetrates through the inner side of the fixing tripod, a screw hole is formed in the top end of the connecting fixing seat, a second fixing rod penetrates through the top of the screw hole, a second fixing knob is arranged at the inner side of the second fixing rod, a first fixing rod is arranged at the left end of the second fixing rod, the first fixing knob is arranged at the inner side of the first fixing rod, and a light source connector is fixed at the bottom, the inner side of the light source connector is provided with an inner wire, the inside of the light source connector is screwed with a laser tube, the outer side of the upper section of the laser tube is provided with an outer wire, the input wire connector is arranged at the top of the connecting fixing seat, a second connecting wire penetrates through the top end of the input wire connector, the current controller is arranged at the left side of the second connecting wire, the outer wall of the current controller is provided with a first connecting wire, the pulse generator is fixed at one end of the first connecting wire far away from the current controller, the outer side of the second connecting wire is provided with a buckle, the outer wall of the buckle is connected with a thin rope, the bottom of the right side of the thin rope is provided with a weight, the outer wall of the thin rope is provided with a pulley, the inner side of the pulley is provided with a movable groove, a fixing body penetrates through the inside of the movable groove, the, the top of the cross arm joint penetrates through the supporting body, the inner side of the skull block is provided with a fixed cross rod, and the top of the fixed cross rod penetrates through a third bolt.
Preferably, the first fixing rod forms a rotating structure through the first fixing knob, and the inner side of the light source connector at the bottom end of the first fixing rod is attached to the top of the laser tube.
Preferably, the diameter of the circle of the section of the second fixing rod is larger than that of the circle of the section of the first fixing rod, and the bottom of the second fixing rod is vertically connected with the connecting fixing seat.
Preferably, the buckle is located at one third of the outer side of the second connecting line, and the length of the second connecting line is 1 m.
Preferably, the pulley and the fixed body form a movable device through a movable groove, and the diameter of a circle with the section of the pulley is 6 cm.
Preferably, the cross arm is connected with the outer wall of the cross arm joint in a welding mode, and the center line of the cross arm joint is overlapped with the center line of the support body.
Preferably, the area of the copper mesh is smaller than that of the skull block, and the thickness of the copper mesh is 5 mm.
Preferably, there are two sets of first bolts equidistance, and first bolt is symmetrical about the axis of copper mesh.
Preferably, the outer wire and the inner wire form threaded connection, and the central axis of the outer wire is flush with the central axis of the inner wire.
Compared with the prior art, the invention has the beneficial effects that: the anti-drop wearable eye stimulation device for the experimental animal is provided with a main body, the area of a skull block on the inner side of the main body is larger than that of a copper net, the intracranial administration tube, the electrode and the like of the experimental animal can be embedded under the combined action of the copper net and a fixed cross rod, enough position space is provided, two groups of first bolts are arranged at equal intervals, the stability of a fixed tripod and the fixed cross rod on the skull block can be enhanced through the screwing and fixing action of the first bolts, meanwhile, a first fixed rod forms a rotating structure through the first fixed knob, the bending angle of the first fixed rod can be changed through the action of the first fixed knob, so that a light source emitted by a laser tube can better stimulate eyes, the diameter of a circle where the section of a second fixed rod is larger than that of the circle where the section of the first fixed rod is located, under the action of the second fixed knob, can extend the operation to the horizontal direction to the first dead lever, ensure the device to work normally, and the buckle is located the third department outside the second connecting wire, through the effect of buckle to the second connecting wire, can make the second connecting wire difficult to rock, reduce the bearing capacity of the main part in the activity, the pulley passes through the movable groove and constitutes the mobile device with the fixed body, when the main part is moving, drive the string, and the string passes through the effect of pulley, can reduce the resistance, make the activity of the main part not influenced, meanwhile, the connection mode of xarm and xarm joint outer wall is the welding, can strengthen the connectivity between xarm and xarm joint, and under the effect of xarm joint, can make the steadiness between xarm and the support strengthen, and the outer silk forms threaded connection with the inner silk, the laser pipe passes through the combined action of outer silk and inner silk with the light source joint, the laser tubes with different wavelengths can be replaced, the eye stimulation work is more perfect, a pulse generator in the device can send out pulse voltage with specific time and frequency, and the current controller can convey control current.
Drawings
FIG. 1 is a schematic structural view of a wearable eye stimulation device for an anti-drop experimental animal according to the present invention;
FIG. 2 is a schematic side view of a connection fixing seat of the wearable eye stimulation device for an anti-drop experimental animal according to the present invention;
FIG. 3 is a schematic view of the top structure of a copper mesh of a wearable eye stimulation device for an anti-drop experimental animal according to the present invention;
FIG. 4 is a schematic view of the inner side structure of the light source connector of the wearable eye stimulation device for the anti-drop experimental animal of the present invention;
fig. 5 is a schematic side view of a pulley of the wearable eye stimulation device for anti-drop laboratory animals according to the present invention.
In the figure: 1. the laser tube comprises a main body, 2, eyes, 3, a laser tube, 4, a light source connector, 5, a first fixing rod, 6, a first fixing knob, 7, a pulse generator, 8, a first connecting line, 9, a current controller, 10, a second fixing knob, 11, a second fixing rod, 12, a connecting fixing seat, 13, a second connecting line, 14, a buckle, 15, a string, 16, a pulley, 17, a cross arm, 18, a cross arm connector, 19, a weight, 20, a support body, 21, a copper net, 22, a skull block, 23, a first bolt, 24, a fixing tripod, 25, a screw hole, 26, an input line connector, 27, a second bolt, 28, a fixing cross rod, 29, a third bolt, 30, an outer wire, 31, an inner wire, 32, a movable groove, 33 and a fixing body.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-5, the present invention provides a technical solution: an anti-drop wearable transocular stimulation device for experimental animals comprises a main body 1, eyes 2, a laser tube 3, a light source connector 4, a first fixing rod 5, a first fixing knob 6, a pulse generator 7, a first connecting wire 8, a current controller 9, a second fixing knob 10, a second fixing rod 11, a connecting fixing seat 12, a second connecting wire 13, a buckle 14, a string 15, a pulley 16, a cross arm 17, a cross arm connector 18, a weight 19, a support body 20, a copper net 21, a skull block 22, a first bolt 23, a fixing tripod 24, a screw hole 25, an input wire connector 26, a second bolt 27, a fixing cross bar 28, a third bolt 29, an outer wire 30, an inner wire 31, a movable groove 32 and a fixing body 33, wherein the eyes 2 are positioned on the inner side of the main body 1, the skull block 22 is fixed in the main body 1, the copper net 21 is arranged at the top end of the skull block 22, and the fixing tripod 24 is arranged at the top of the copper net 21, the area of the copper mesh 21 is smaller than that of the skull block 22, the thickness of the copper mesh 21 is 5mm, under the combined action of the copper mesh 21 and the fixed cross bar 28, the intracranial administration tube, the electrode and the like of an experimental animal can be embedded, and enough position space is provided, the top end of the right side of the fixed tripod 24 is penetrated with a first bolt 23, the top of the fixed tripod 24 is provided with a connecting fixed seat 12, two groups of the first bolts 23 are arranged at equal intervals, the first bolts 23 are symmetrical about the central axis of the copper mesh 21, the stability of the fixed tripod 24 and the fixed cross bar 28 on the skull block 22 can be enhanced through the screwing action of the first bolt 23, the inner side of the fixed tripod 24 is penetrated with a second bolt 27, the top end of the connecting fixed seat 12 is provided with a screw hole 25, the top of the screw hole 25 is penetrated with a second fixed bar 11, the diameter of the circle where the section of the second fixed bar 11 is larger than that of the section of the first fixed bar, the bottom of the second fixing rod 11 is vertically connected with the connecting fixing seat 12, under the action of the second fixing knob 10, the first fixing rod 11 can be horizontally extended to ensure the normal operation of the device, the second fixing knob 10 is arranged on the inner side of the second fixing rod 11, the left end of the second fixing rod 11 is provided with the first fixing rod 5, the first fixing rod 5 forms a rotating structure through the first fixing knob 6, the inner side of the light source connector 4 at the bottom end of the first fixing rod 5 is attached to the top of the laser tube 3, the bending angle of the first fixing rod 5 can be changed through the action of the first fixing knob 6, so that the light source emitted by the laser tube 3 can better stimulate the eyes 2, the first fixing knob 6 is arranged on the inner side of the first fixing rod 5, the bottom end of the first fixing rod 5 is fixed with the light source connector 4, the inner side of the light source connector 4 is provided with an inner wire 31, the laser tube 3 is screwed in the light source connector 4, the outer wire 30 is arranged on the outer side of the upper section of the laser tube 3, the outer wire 30 and the inner wire 31 form threaded connection, the central axis of the outer wire 30 is level with the central axis of the inner wire 31, the laser tube 3 and the light source connector 4 can replace the laser tubes 3 with different wavelengths through the combined action of the outer wire 30 and the inner wire 31, so that the visual stimulation work is more complete, the input wire connector 26 is arranged at the top of the connecting fixing seat 12, the second connecting wire 13 penetrates through the top end of the input wire connector 26, the current controller 9 is arranged on the left side of the second connecting wire 13, the first connecting wire 8 is arranged on the outer wall of the current controller 9, the pulse generator 7 is fixed at one end of the first connecting wire 8, which is far away from the current controller 9, the buckle 14 is arranged on the outer side of the second connecting wire 13, the outer wall of the buckle 14 is connected with the thin rope 15, the buckle 14, the length of the second connecting line 13 is 1m, the second connecting line 13 is not easy to shake through the action of the buckle 14 on the second connecting line 13, the bearing capacity of the main body 1 in movement is reduced, a weight 19 is installed at the bottom of the right side of the thin rope 15, the pulley 16 is arranged on the outer wall of the thin rope 15, the pulley 16 and the fixed body 33 form a movable device through a movable groove 32, the diameter of a circle where the cross section of the pulley 16 is located is 6cm, when the main body 1 moves, the thin rope 15 is driven, the resistance can be reduced through the action of the pulley 16, the movement of the main body 1 is not affected, a movable groove 32 is arranged on the inner side of the pulley 16, the fixed body 33 penetrates through the movable groove 32, the cross arm 17 is installed on the left side of the fixed body 33, the right end of the cross arm 17 is fixed with the cross arm joint 18, the connection mode of the cross arm 17 and the outer wall of the joint 18 is welding, and the center line of the cross arm, the connection between the cross arm 17 and the cross arm joint 18 can be enhanced, and under the action of the cross arm joint 18, the stability between the cross arm 17 and the support 20 can be enhanced, the support 20 penetrates through the top of the cross arm joint 18, the fixed cross rod 28 is arranged on the inner side of the skull block 22, and the third bolt 29 penetrates through the top of the fixed cross rod 28.
The working principle of the embodiment is as follows: the wearable eye stimulation device for the anti-drop experimental animal comprises a pulse generator 7, a current controller 9, a laser tube 3, a first fixing knob 6, a second fixing knob 10, a second fixing knob 6, a first fixing knob 6, a second fixing knob 6, a first fixing rod 11, a second fixing knob 6, a first fixing rod 5, a second fixing knob 6, a second fixing knob 10 and a third fixing knob 6, wherein the pulse generator 7 is started to send out pulse voltage with specific time and frequency, the current controller 9 can convey control current, stimulation with stable angle, light intensity and time is provided by adjusting the magnitude of input current, when current passes through the second connecting wire 13, eye stimulation work is carried out on eyes 2 of the experimental animal under the action of the laser tube 3, meanwhile, the diameter of a circle where the section of the second fixing rod 11 is located is larger than that of the section of the first fixing rod 5, horizontal direction extension operation can be carried out on the first fixing rod, the light source emitted by the laser tube 3 can better stimulate the eyes 2, meanwhile, the area of the copper mesh 21 is smaller than that of the skull block 22, the connectivity between the fixed tripod 24 and the skull block 22 can be enhanced through the arrangement of the first bolt 23, the laser tube 3 and the light source joint 4 can replace the laser tube 3 with different wavelengths through the combined action of the outer wire 30 and the inner wire 31 under the combined action of the copper mesh 21 and the fixed cross bar 28, so that the intracranial administration tube, the electrode and the like of an experimental animal can be embedded, and enough position space is provided, the outer wire 30 and the inner wire 31 form threaded connection, the laser tube 3 and the light source joint 4 can ensure that the eye stimulation work is more perfect, the execution of higher brain functions is influenced, the buckle 14 is positioned at one third of the outer side of the second connecting wire 13, the second connecting wire 13 is not easy to shake through the action of the buckle 14 on the second connecting wire 13, and the bearing capacity of the main body 1 in the movement is reduced, and the pulley 16 and the fixed body 33 form a movable device through the movable groove 32, when the main body 1 moves, the string 15 is driven, and the string 15 can reduce the resistance through the combined action of the pulley 16 and the weight 19, so that the movement of the main body 1 is not influenced.
Although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that various changes in the embodiments and/or modifications of the invention can be made, and equivalents and modifications of some features of the invention can be made without departing from the spirit and scope of the invention.
Claims (9)
1. The utility model provides an anti-drop laboratory animal is with wearable target stimulation device, includes main part (1), first fixed knob (6), pulse generator (7), current controller (9), copper mesh (21) and input line connector (26), its characterized in that: during the experiment, the eyes (2) are positioned on the inner side of the main body (1), the skull block (22) is fixed inside the main body (1), the copper net (21) is arranged at the top end of the skull block (22), the top of the copper net (21) is provided with the fixing tripod (24), the right top end of the fixing tripod (24) is penetrated with the first bolt (23), the top of the fixing tripod (24) is provided with the connecting fixing seat (12), the inner side of the fixing tripod (24) is penetrated with the second bolt (27), the top end of the connecting fixing seat (12) is provided with the screw hole (25), the top of the screw hole (25) is penetrated with the second fixing rod (11), the inner side of the second fixing rod (11) is provided with the second fixing knob (10), the left end of the second fixing rod (11) is provided with the first fixing rod (5), the first fixing knob (6) is arranged on the inner side of the first fixing rod (5), a light source connector (4) is fixed at the bottom end of the first fixing rod (5), an inner wire (31) is arranged on the inner side of the light source connector (4), a laser tube (3) is screwed in the light source connector (4), an outer wire (30) is arranged on the outer side of the upper section of the laser tube (3), the input wire connector (26) is arranged at the top of the connecting fixing seat (12), a second connecting wire (13) penetrates through the top end of the input wire connector (26), the current controller (9) is arranged on the left side of the second connecting wire (13), a first connecting wire (8) is arranged on the outer wall of the current controller (9), the pulse generator (7) is fixed at one end, away from the current controller (9), of the first connecting wire (8), a buckle (14) is arranged on the outer side of the second connecting wire (13), and a string (15) is connected to the outer wall of the buckle (14), weight (19) are installed to the right side bottom of string (15), and the outer wall of string (15) is provided with pulley (16), the inboard of pulley (16) is settled there is activity groove (32), and the inside of activity groove (32) runs through and has fixed body (33), xarm (17) is installed in the left side of fixed body (33), and the right-hand member of xarm (17) is fixed with xarm joint (18), the top that xarm joint (18) runs through has supporter (20), the inboard of skull piece (22) is provided with fixed horizontal pole (28), and the top of fixed horizontal pole (28) runs through has third bolt (29).
2. The anti-drop wearable transocular stimulation device for experimental animals according to claim 1, characterized in that: first dead lever (5) constitute revolution mechanic through first fixed knob (6), and the inboard of light source joint (4) of first dead lever (5) bottom is laminated with the top of laser pipe (3) mutually.
3. The anti-drop wearable transocular stimulation device for experimental animals according to claim 1, characterized in that: the diameter of the circle of the section of the second fixing rod (11) is larger than that of the circle of the section of the first fixing rod (5), and the bottom of the second fixing rod (11) is vertically connected with the connecting fixing seat (12).
4. The anti-drop wearable transocular stimulation device for experimental animals according to claim 1, characterized in that: the buckle (14) is positioned at one third of the outer side of the second connecting line (13), and the length of the second connecting line (13) is 1 m.
5. The anti-drop wearable transocular stimulation device for experimental animals according to claim 1, characterized in that: the pulley (16) and the fixed body (33) form a movable device through a movable groove (32), and the diameter of a circle where the section of the pulley (16) is located is 6 cm.
6. The anti-drop wearable transocular stimulation device for experimental animals according to claim 1, characterized in that: the cross arm (17) and the outer wall of the cross arm joint (18) are connected in a welding mode, and the center line of the cross arm joint (18) is overlapped with the center line of the support body (20).
7. The anti-drop wearable transocular stimulation device for experimental animals according to claim 1, characterized in that: the area of the copper net (21) is smaller than that of the skull block (22), and the thickness of the copper net (21) is 5 mm.
8. The anti-drop wearable transocular stimulation device for experimental animals according to claim 1, characterized in that: the first bolts (23) are arranged in two groups at equal intervals, and the first bolts (23) are symmetrical about the central axis of the copper mesh (21).
9. The anti-drop wearable transocular stimulation device for experimental animals according to claim 1, characterized in that: the outer wire (30) and the inner wire (31) form threaded connection, and the central axis of the outer wire (30) is flush with the central axis of the inner wire (31).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810161113.8A CN108464814B (en) | 2018-02-27 | 2018-02-27 | Anti-drop experimental animals is with wearable eye stimulation device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810161113.8A CN108464814B (en) | 2018-02-27 | 2018-02-27 | Anti-drop experimental animals is with wearable eye stimulation device |
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| CN108464814A CN108464814A (en) | 2018-08-31 |
| CN108464814B true CN108464814B (en) | 2021-02-02 |
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| CN110215204B (en) * | 2019-06-12 | 2023-11-28 | 中国科学院苏州生物医学工程技术研究所 | Laboratory is with mouse heart rate check out test set |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994025857A1 (en) * | 1993-05-04 | 1994-11-10 | Brisalebe Ag | Evaluating animals using eye characteristics |
| CN103033917A (en) * | 2011-10-08 | 2013-04-10 | 耶拿研究有限责任公司 | Flexible nonlinear laser scanning microscope for noninvasive three-dimensional detection |
| CN103976709A (en) * | 2014-04-24 | 2014-08-13 | 中国科学院苏州生物医学工程技术研究所 | Wearable array transducer probe and small animal brain function photoacoustic imaging system |
| CN107693962A (en) * | 2017-08-31 | 2018-02-16 | 深圳先进技术研究院 | A kind of wear-type ultrasonic conducting device |
-
2018
- 2018-02-27 CN CN201810161113.8A patent/CN108464814B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994025857A1 (en) * | 1993-05-04 | 1994-11-10 | Brisalebe Ag | Evaluating animals using eye characteristics |
| CN103033917A (en) * | 2011-10-08 | 2013-04-10 | 耶拿研究有限责任公司 | Flexible nonlinear laser scanning microscope for noninvasive three-dimensional detection |
| CN103976709A (en) * | 2014-04-24 | 2014-08-13 | 中国科学院苏州生物医学工程技术研究所 | Wearable array transducer probe and small animal brain function photoacoustic imaging system |
| CN107693962A (en) * | 2017-08-31 | 2018-02-16 | 深圳先进技术研究院 | A kind of wear-type ultrasonic conducting device |
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