CN108452222A - 一种用于骨科疼痛的中药药酒及制备方法 - Google Patents

一种用于骨科疼痛的中药药酒及制备方法 Download PDF

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CN108452222A
CN108452222A CN201810378363.7A CN201810378363A CN108452222A CN 108452222 A CN108452222 A CN 108452222A CN 201810378363 A CN201810378363 A CN 201810378363A CN 108452222 A CN108452222 A CN 108452222A
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余红岗
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Abstract

本发明涉及用于骨科疼痛的中药药酒及制备方法。所述药酒包括：木香5‑15份，鸡血藤5‑13份，白术13‑15份，赤芍8‑12份，香附5‑10份，茯苓13‑20份，木通5‑10份，淫霍13‑20份，狗脊3‑10份，桑枝13‑20份，宽根藤5‑10份，桑寄生15‑20份，羌活8‑15份，三棱2‑10份，海桐6‑8份，当归8‑10份，防风5‑10份，黄芪13‑20份，丝木13‑15份，草乌2‑5份，五加皮6‑8份，杜仲13‑15份，威灵仙8‑10份，秦艽8‑20份，防已13‑15份，千年健13‑15份，伸筋草5‑10份，川芎1‑5份，生地13‑15份，桂枝13‑20份。上述药酒可软坚散结活血化瘀。

Description

一种用于骨科疼痛的中药药酒及制备方法
技术领域
本发明涉及中医药领域，具体涉及一种用于骨科疼痛的中药药酒及制备方法。
背景技术
近年来，在临床中颈腰椎病、肩周炎、骨性关节病、风湿性关节病、滑膜炎、足跟痛、跌打损伤及骨折等骨科疼痛疾病发病率逐年上升，尤其是颈肩腰腿疼疾病向年轻化发展。目前对该类疾病治疗方法多元化，以药物镇痛、物理治疗、传统理疗以及中医中药的治疗为主。而中医中药的治疗标本兼治，无毒副作用，深受广大患者的接受。基于对治疗效果的追求，发明一种疗效更好，更确切，治愈率高的中药势在必行。
专利CN101168041公开了一种治疗风湿病的药物，以下按重量比计算，它包括野西瓜1-50、黑附子1-30、白芥子1-28、干姜1-30、辣椒1-30、威灵仙1-10、淫羊藿1-10、肉桂1-30、川乌1-10、花椒1-28、防风1-10、桂枝1-10、独活1-10、麻黄1-10、川芎1-12、甘草1-7、当归2-10、大蒜1-23和葱白1-23。其主治病症：风湿、类风湿、肩周炎、颈椎病、骨质增生引起的颈椎、腰椎骨刺、腰腿痛、椎间盘突出、关节劳损等无菌性炎症，妇女月经不调、胃寒、气管炎、痢疾、大便软硬、脘腹胀满胀痛、气不顺、手脚麻木疼痛、肌肉痛、中风半身不遂、偏头痛等因风湿风寒引起的病症。但在临床实践中发现，该处方虽然用来治疗皮肤病比较好，但是，处方中含有刺激性较强的白芥子、干姜、辣椒、大蒜，患者在外用时容易出现患处起泡、组织液外流的现象，并且起泡组织液外流的患处容易留下色素沉着，病人不容易接受。
发明内容
基于上述缺陷，本发明提供一种用于骨科疼痛的中药药酒及其制备方法。
所述中药药酒的活性成分按照重量份计，包括(由以下组分组成)：
木香5-15份，鸡血藤5-13份，白术13-15份、赤芍8-12份、香附5-10份，茯苓13-20份、木通5-10份，淫霍13-20份，狗脊3-10份，桑枝13-20份、宽根藤5-10份，桑寄生15-20份、羌活8-15份，三棱2-10份，海桐6-8份，当归8-10份、防风5-10份，黄芪13-20份、丝木13-15份、草乌2-5份，五加皮6-8份，杜仲13-15份、威灵仙8-10份，秦艽8-20份、防已13-15份、千年健13-15份、伸筋草5-10份，川芎1-5份、生地13-15份、桂枝13-20份。
还可进一步包括辅料：樟脑粉15-25份，以及乙醇。
优选地，所述活性成分与乙醇的比例为(256-332)/2500(g/mL)；
或，所述所述樟脑粉与乙醇的比例为(15-25)/2500(g/mL)。
本发明所述的中药药酒，优选地，所述中药药酒的活性成分按照重量份计，包括(由以下组分组成)：
木香5-8份，鸡血藤5-8份，白术13-15份、赤芍8-10份、香附5-7份，茯苓13-15份、木通5-8份，淫霍13-15份，狗脊3-6份，桑枝13-15份、宽根藤5-8份，桑寄生15-20份、羌活8-10份，三棱2-6份，海桐6-8份，当归8-10份、防风5-10份，黄芪13-15份、丝木13-15份、草乌2-5份，五加皮6-8份，杜仲13-15份、威灵仙8-10份，秦艽8-10份、防已13-15份、千年健13-15份、伸筋草5-10份，川芎1-5份、生地13-15份、桂枝13-15份。
作为本发明的进一步优选技术方案，所述中药药酒由以下成分组成：
木香5-6份，鸡血藤7-8份，白术13-14份、赤芍8-10份、香附5-7份，茯苓13-14份、木通5-6份，淫霍13-15份，狗脊4-6份，桑枝13-15份、宽根藤5-8份，桑寄生16-20份、羌活8-10份，三棱4-6份，海桐6-8份，当归8-10份、防风8-10份，黄芪13-15份、丝木13-15份、草乌3-5份，五加皮6-8份，杜仲13-15份、威灵仙8-10份，秦艽8-10份、防已13-15份、千年健13-15份、伸筋草8-10份，川芎3-5份、生地13-15份、桂枝13-15份、樟脑粉15-25份，以及乙醇。
本发明中药药酒主治：肩周炎、颈椎病、关节炎、腰椎间盘突出、陈年老伤、风湿肿痛、关节疼痛、关节积液、筋骨拉伤、关节麻木、淤伤肿痛、骨折骨裂、肌肉拉伤、新伤、关节麻木无力、骨头坏死、软组织损伤等常见骨科及疼痛疾病。
中医、中药外治，可以标本兼治、祛邪扶正，并且无副作用、无过敏、无感染，深受患者的接受和信任。
本发明中药药酒配方设计合理，使用方便，不影响患者日常生活和工作，且无痛苦和副作用，用于治疗骨科及疼痛疾病疗效又快又好。本发明的中药药酒有消肿止痛、活血化瘀、祛风燥湿功效，且能软坚散结、扩张血管，促使血液循环，从而消除疼痛麻木，以达到立竿见影的效果。
本发明一并提供上述中药药酒的制备方法，
取所述中药药酒中的活性成分(即除樟脑粉、乙醇以外的全部组分)，烘干后粉碎，过80目筛，以乙醇浸泡，密封后置于避光处保存15-30天。每3天搅动或摇动1至2次，泡制后取液体经过滤后加入樟脑粉，存放30-40小时后即得。
优选地，根据季节不同，所述以乙醇浸泡的时间也不同，春天浸泡25天，夏天浸泡15天，秋天浸泡25天，冬天浸泡30天。
本发明提供上述中药药酒使用方法：
首先将喷剂轻轻摇匀，喷洒在颈肩腰腿痛疼痛部位，(根据经络学原理，气血行于十二经络，)让人体经络气血畅通。在需要“治疗”的部位，(颈肩腰腿疼痛部位)用热毛巾擦拭疼痛部位1分钟，将所述中药药酒摇匀喷于疼痛部位5ml左右，通过经络运行气血原理及物理现象，使药效持续深层渗透皮肤，疏经活络，达到消肿止痛的效果。
喷洒药液时，可配上简单轻揉力度手法，帮助疼痛部位放松，便于药效更好的吸收。
一个疗程6次，每次3-5ml，轻度疼痛者一个疗程，中度疼痛者二个疗程，重度疼痛者三个疗程。
具体实施方式
以下实施例用于说明本发明，但不用来限制本发明的范围。
实施例1
本实施例提供一种中药药酒，由以下组分组成：
木香5克，鸡血藤8克，白术13克、赤芍8克、香附7克，茯苓14克、木通5克，淫霍13克，狗脊5克，桑枝13克、宽根藤5克，桑寄生16克、羌活8克，三棱4克，防风8克，海桐6克，当归8克、黄芪13克、丝木13克、草乌3克，五加皮6克，杜仲13克、威灵仙8克，秦艽8克、防已13克、千年健15克、伸筋草8克，川芎4克、生地13克、桂枝13克、樟脑粉20克，以及乙醇2500ml。
实施例2
本实施例提供一种中药药酒，由以下组分组成：
木香5克，鸡血藤8克，白术13克、赤芍10克、香附6克，茯苓13克、木通6克，淫霍14克，狗脊5克，桑枝15克、宽根藤8克，桑寄生20克、羌活10克，三棱6克，防风8克，海桐8克，当归10克、黄芪15克、丝木13克、草乌3克，五加皮7克，杜仲14克、威灵仙8克，秦艽8克、防已14克、千年健15克、伸筋草10克，川芎4克、生地14克、桂枝15克、樟脑粉20克，以及乙醇2500ml。
实施例3
本实施例提供一种中药药酒，由以下组分组成：
木香15克，鸡血藤12克，白术13克、赤芍12克、香附8克，茯苓20克、木通10克，淫霍13克，狗脊10克，桑枝15克、宽根藤5克，桑寄生20克、羌活15克，三棱10克，防风10克，海桐6克，当归10克、黄芪13克、丝木13克、草乌2克，五加皮8克，杜仲15克、威灵仙10克，秦艽20克、防已15克、千年健15克、伸筋草10克，川芎1克、生地13克、桂枝20克、樟脑粉20克，以及乙醇2500ml。
实施例4
本实施例提供一种中药药酒，由以下组分组成：
木香8克，鸡血藤13克，白术14克、赤芍12克、香附10克，茯苓20克、木通10克，淫霍16克，狗脊9克，桑枝20克、宽根藤10克，桑寄生20克、羌活12克，三棱9克，防风8克，海桐8克，当归8克、黄芪17克、丝木14克、草乌4克，五加皮7克，杜仲15克、威灵仙10克，秦艽16克、防已15克、千年健15克、伸筋草10克，川芎5克、生地14克、桂枝17克、樟脑粉20克，以及乙醇2500ml。
实施例5
本实施例提供一种中药药酒及其制备方法，有如下步骤：
木香5克，鸡血藤8克，白术13克、赤芍8克、香附7克，茯苓14克、木通5克，淫霍13克，狗脊5克，桑枝13克、宽根藤5克，桑寄生16克、羌活8克，三棱4克，防风8克，海桐6克，当归8克、黄芪13克、丝木13克、草乌3克，五加皮6克，杜仲13克、威灵仙8克，秦艽8克、防已13克、千年健15克、伸筋草8克，川芎4克、生地13克、桂枝13克，将上述全部物料烘干后粉碎，过80目筛，以2500ml乙醇浸泡，密封后置于避光处保存20天。每3天搅动或摇动1至2次，泡制后取液体经过滤后加入樟脑粉20克，存放30小时后即得。
对比例1
本对比例提供一种中药药酒，与实施例1的区别仅在于，将狗脊替换为野西瓜，将羌活替换为独活。
对比例2
本对比例提供一种中药药酒，与实施例1的区别仅在于，所述药酒中还包括萆薢5克，菟丝子15克。
对比例3
本对比例提供一种中药药酒，与实施例1的区别仅在于，乙醇的用量为1500ml。
试验例1
本试验例提供几例典型案例如下：
病例一：张X，男，49岁，南京市人，患坐骨神经痛、腰椎突出压迫神经根、腰痛、腿疼痛，行动受限，步行十分钟就无法继续行走，曾去过数家医院求治无效。后经使用本发明所提供的中药药酒三疗程，正常工作生活，目前已3年从未复发。
病例二：李X，女，52岁，南昌市人，患风湿痛，行动受限，无法长距离行走。后经使用本发明所提供的中药药酒两疗程后，2年后回访，发现2年内无复发。
病例三：李X，女，54岁，南昌市人，颈椎病多年，由颈椎病造成的头痛头晕、乏力等症状困扰患者多年。经使用本发明所提供的中药药酒三疗程后，1年后回访，发现1年内症状显著减轻，生活质量明显提高。
上述临床试验证明，本发明是治疗骨科疼痛的有效药物，配伍精当，疗效显著，无毒无副作用，治愈率高达97％，且材料简单易得，制作工艺简单，耗费成本低，主要用于颈腰椎病、肩周炎、骨性关节病、风湿性关节病、滑膜炎、足跟痛、跌打损伤及骨折等骨科疼痛疾病，具有实际的临床意义和良好的推广应用价值。
试验例2
本试验例提供实施例1-4所提供的中药药酒治疗痹病(风关痛、类关炎)的临床试验资料。
试验对象：风关痛、类关炎病人180人。随机分为6组，每组30人。
试验方法：将6组病人分为空白组，对照组，实施例1组，实施例2组，实施例3组，实施例4组。
对照组采用云南白药气雾剂进行治疗，实施例1-4组分别采用实施例1-4所提供的中药药酒进行治疗。共治疗2个月。
空白组为以安慰剂喷施治疗。
试验结果：经2个月治疗后，结果如表1所示：
表1
“无效”为病人无明显改善，疼痛、行动能力均无改变。
“显效”为疼痛症状缓解，行动能力增强，仍存在疼痛情况，但频率降低。
“有效”为彻底缓解疼痛，行动能力大大增强，生活质量显著提高。
有效率＝(显效人数+有效人数)/150×100％。
根据上述试验结果，可明显看出，本发明对于骨科疼痛均具有较好的治疗效果。
虽然实施例3和对比例3的有效率均为90％，但从“显效”和“有效”人数分布来看，实施例3仍优于对比例3。且对比例3成本较高，不利于商业普及。
虽然，上文中已经用一般性说明、具体实施方式及试验，对本发明作了详尽的描述，但在本发明基础上，可以对之作一些修改或改进，这对本领域技术人员而言是显而易见的。因此，在不偏离本发明精神的基础上所做的这些修改或改进，均属于本发明要求保护的范围。

Claims (7)

1.一种中药药酒，其特征在于，所述中药药酒中的活性成分按照重量份计，包括：
木香5-15份，鸡血藤5-13份，白术13-15份，赤芍8-12份，香附5-10份，茯苓13-20份，木通5-10份，淫霍13-20份，狗脊3-10份，桑枝13-20份，宽根藤5-10份，桑寄生15-20份，羌活8-15份，三棱2-10份，海桐6-8份，当归8-10份，防风5-10份，黄芪13-20份，丝木13-15份，草乌2-5份，五加皮6-8份，杜仲13-15份，威灵仙8-10份，秦艽8-20份，防已13-15份，千年健13-15份，伸筋草5-10份，川芎1-5份，生地13-15份，桂枝13-20份。
2.根据权利要求1所述的中药药酒，其特征在于，所述中药药酒中的活性成分按照重量份计，包括：
木香5-8份，鸡血藤5-8份，白术13-15份，赤芍8-10份，香附5-7份，茯苓13-15份，木通5-8份，淫霍13-15份，狗脊3-6份，桑枝13-15份，宽根藤5-8份，桑寄生15-20份，羌活8-10份，三棱2-6份，海桐6-8份，当归8-10份，防风5-10份，黄芪13-15份，丝木13-15份，草乌2-5份，五加皮6-8份，杜仲13-15份，威灵仙8-10份，秦艽8-10份，防已13-15份，千年健13-15份，伸筋草5-10份，川芎1-5份，生地13-15份，桂枝13-15份。
3.根据权利要求1或2所述的中药药酒，其特征在于，还包括：樟脑粉15-25份，乙醇。
4.根据权利要求1-3任一项所述的中药药酒，其特征在于，所述活性成分与乙醇的比例为(256-332)/2500。
5.根据权利要求3或4所述的中药药酒，其特征在于，所述樟脑粉与乙醇的比例为(15-25)/2500。
6.根据权利要求1-5任一项所述的中药药酒，其特征在于，所述中药药酒由以下成分组成：
木香5-6份，鸡血藤7-8份，白术13-14份，赤芍8-10份，香附5-7份，茯苓13-14份，木通5-6份，淫霍13-15份，狗脊4-6份，桑枝13-15份，宽根藤5-8份，桑寄生16-20份，羌活8-10份，三棱4-6份，海桐6-8份，当归8-10份，防风8-10份，黄芪13-15份，丝木13-15份，草乌3-5份，五加皮6-8份，杜仲13-15份，威灵仙8-10份，秦艽8-10份，防已13-15份，千年健13-15份，伸筋草8-10份，川芎3-5份，生地13-15份，桂枝13-15份，樟脑粉15-25份，以及乙醇。
7.制备权利要求1-6任一项所述的中药药酒的方法，其特征在于，取所述中药药酒中的活性成分烘干后粉碎，过80目筛，以乙醇浸泡，密封后置于避光处保存15-30天；
每3天搅动或摇动1至2次，泡制后取液体经过滤后加入樟脑粉，存放30-40小时后即得。
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1628802A (zh) * 2004-10-14 2005-06-22 蔡建平 中药火疗保健舒服液
CN104107338A (zh) * 2013-04-17 2014-10-22 商月波 一种治疗风湿病的药酒

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1628802A (zh) * 2004-10-14 2005-06-22 蔡建平 中药火疗保健舒服液
CN104107338A (zh) * 2013-04-17 2014-10-22 商月波 一种治疗风湿病的药酒

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