CN108450466A - A kind of composition pesticide containing cyflumetofen and its application in pest control - Google Patents
A kind of composition pesticide containing cyflumetofen and its application in pest control Download PDFInfo
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- CN108450466A CN108450466A CN201810247142.6A CN201810247142A CN108450466A CN 108450466 A CN108450466 A CN 108450466A CN 201810247142 A CN201810247142 A CN 201810247142A CN 108450466 A CN108450466 A CN 108450466A
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing within the same carbon skeleton a carboxylic group or a thio analogue, or a derivative thereof, and a carbon atom having only two bonds to hetero atoms with at the most one bond to halogen, e.g. keto-carboxylic acids
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/24—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms
- A01N43/26—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms five-membered rings
- A01N43/28—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms five-membered rings with two hetero atoms in positions 1,3
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Abstract
The present invention provides a kind of composition pesticide containing cyflumetofen and its applications in pest control.The active ingredient for containing the composition pesticide of cyflumetofen is 1 containing 4 pairs of phenoxy-phenoxy methyl structurals, 3 dioxolane compounds and cyflumetofen, compounded by the two, and it is found by testing detection, the drug effect of the composition pesticide is apparently higher than the preventive effect of single dose insecticide ingredient, so reducing the dosage of composition, significantly reduce the resistance risk of pest, the service efficiency for improving composition pesticide, so as to increase crop yield while significantly reducing the pollution to environment.Therefore, the composition pesticide provided by the present invention containing cyflumetofen has good market potential and wide application prospect in terms of pest control.
Description
Technical field
The invention belongs to composition pesticide technical field, more particularly to a kind of composition pesticide containing cyflumetofen and its
Application in pest control.
Background technology
The use of pesticide has very long history, and huge effect has been played in the process of mankind's nature remodeling,
The great development for promoting agricultural, huge economic benefit is brought to the mankind.China is in B.C. seventh century to B.C. fiveth century
Pest is killed with thick grass, clam charcoal ash, male bring up etc..It is with natural drug and inorganic compound pesticide before the 1940s
Based on natural and inorganic drug epoch；Since early in the twentieth century, into the epoch of synthetic organic pesticide.The hair of pesticide at present
Spread gesture：Developed country has been enter into Cultivar replacing from the seventies in last century and regenerates, and China's pesticide is begun with from the eighties in last century
Large development, but it is most of establish and grow up on the basis of imitated, until the nineties China's pesticide species just start more
Newly.But pesticide is still based on old kind, and be wherein leading, pesticide species ratio reasonability with high poison, persistent pesticide
It is poor, it is relatively low using technical merit, and dosage is big, it is serious so as to cause environmental pollution.It is practical in the 21st century, agricultural production
The pesticide of application is gradually low to toxicity, active high, the good direction of Environmental compatibility is developed.
Toxicity due to pesticide and its side effect so that there is a series of problem in the long-term use in pesticide,
For example, toxicity of pesticide residual, environmental pollution, ecological balance destruction etc..However, pesticide is still essential production money at present
Material, because this is related to and how to solve world population and increase rapidly, to the active demand problem of agricultural product, therefore it is necessary to develop
The agricultural of high-yield and high-efficiency rather than the organic agriculture for taking low yield, and pesticide is the necessary guarantee of high-efficiency agriculture.
Pest resistance to insecticide is one of the important factor in order that Pesticide use effect is influenced in the real process of agricultural production,
Pest resistance to insecticide refers to producing medicine resistance ability to certain insecticide using pest after insecticide, and this due to the use of killing
Medicine resistance ability caused by worm agent hereditary can go down.Due to chemical pesticide it is long-term, be excessively used, in certain a kind of chemistry
Pesticide use for a period of time after, usual pest all can generate resistivity to this kind of medicament to a certain extent.From species of insect pests
From the point of view of class, drug resistance most species that coleoptera, Diptera and lepidopterous insects generate.The drug resistance of pest can lead to agricultural product
The crop yield influences such as yield declines, farm production cost increases, Pest rampancy can also be to the mankind and environment band due to increasing pesticide
Carry out irreversible harm.In order to solve the problems, such as pest resistance to insecticide, need to develop new drug or selection by different insecticides into
Row compounding, to reach required drug effect.
Invention content
In order to overcome various technological deficiencies existing in the prior art, inventor that one kind dexterously being contained 4- to phenoxy group
1,3-dioxolane class compound and the cyflumetofen of phenoxymethyl structure are compounded, as a kind of new composition pesticide
Active ingredient, with solve that drug resistance existing in the prior art is serious, application method is single and the pest species of effect compared with
Few technical problem, and achieve excellent control effect.
Therefore, the first aspect of the present invention provides a kind of composition pesticide containing cyflumetofen, it includes component A and
B component, the component A are to have following structure the compound of formula (I)：
Wherein, R is selected from following any：Alkyl group, naphthenic base, alkenyl and aryl；
The B component is cyflumetofen；
Also, the weight ratio of the component A and the B component is 40：1~1：40.
Preferably, in the above-mentioned composition pesticide containing cyflumetofen, R is selected from following any：The alkyl group of C1-C10,
The naphthenic base of C3-C10, the aryl of C6-C14.On this basis, R is more preferably the alkyl group of C1-C6, the cycloalkanes of C3-C8
Base, the aryl of C6-C10；R still more preferably be methyl, ethyl, n-propyl, isopropyl, normal-butyl, phenyl, benzyl, naphthalene,
Cyclopropyl, cyclopenta, cyclohexyl.Wherein, R is most preferably ethyl；In other words, it is described containing 4- to phenoxy-phenoxy methyl knot
The 1,3- dioxolane compounds of structure are most preferably 4- to phenoxy group Phenoxymethyl -2- ethyl -1,3- dioxolanes.
In addition, the weight ratio of the component A and the B component is preferably 20：1~1：20, further preferably 8：1~1：
20, or further preferably 8：1~1：8, or further preferably 8：1~1：4, or be still more preferably 4：1~
1：4.
Preferably, the above-mentioned composition pesticide containing cyflumetofen also includes：Auxiliary agent or/and carrier.
It is further preferred that in the above-mentioned composition pesticide containing cyflumetofen, the auxiliary agent be selected from it is following any or
It is a variety of：Wetting agent, dispersant, emulsifier, suspending agent, antifoaming agent, antifreezing agent, binder, thixotropic agent, thickener, film forming agent, pH
Conditioning agent.
Wetting agent is also known as bleeding agent, and main function is that solid material in composition is made to be more easy to be soaked in water.It is carried in the present invention
In the composition pesticide of confession, aliphatic alcohol polyether, sodium butylnaphthalenesulfonate, lauryl sodium sulfate, dodecyl can be selected in wetting agent
Benzene sulfonic acid sodium salt, calcium dodecyl benzene sulfonate (agriculture breast 500#), styryl phenyl polyoxyethylene ether (agriculture breast 601#), sulfomethylated lignin
It is one or more in hydrochlorate, isopropyl naphthalene sulfonate, sodium alklyarylsulfonate, MorwetEFW.
Dispersant be for reducing in composition dispersion system solid or liquid particle aggregation, prepare wettable powder,
Dispersant is added when water dispersible granules, aqueous dispersion tablets, suspending agent, oil suspending agent and is easily formed dispersion liquid and suspension, and protects
Hold stablizing relatively for dispersion.In composition pesticide provided by the invention, dispersant can be selected following any one or more：Phosphorus
Acid esters, Sulfonates, alkylnaphthalene sulfonate condensation polymer, carboxylic acid salt high-molecular, polycarboxylate polymeric modified resin, alkylsurfuric acid
Salt, modified alkyl sulfonate, alkyl naphthalene sulfonic acid condensation polymer sodium salt, naphthalene sulfonate (condensation polymer) class, polycarboxylate polymeric dispersion
Agent, multi-styrene phenylate phosphate dispersant, naphthalenesulfonate formaldehyde condensation compound, alkyl phenol polyoxyethylene ether, formaldehyde condensation products sulphur
Hydrochlorate, lignosulfonates, maleic acid-acrylic acid copolymer sodium salt, alkyl sulfo succinate；Such as Atlox Metasperse
550S、Dispersol BB4、Dispersol CBZ、Terwet 1004、Tersperse 2700、Morwet D-450、
Borresperse CA-SA, sodium tripolyphosphate, 200 solvent naphthas, Nekal BX, YUS-FS3000, YUS-TXC, YUS-FS1,
Tamol NN8906, dispersant NNO.
Emulsifier can promote the liquid that two kinds immiscible in composition to form stabilized emulsion, while be also emulsion
Stabilizer.In composition pesticide provided by the invention, emulsifier can be selected following any one or more：Dodecyl benzene sulfonic acid
Calcium, triphenoethyl benzene phenol polyethenoxy ether, alkyl phenol formaldehyde resin polyoxyethylene ether, fatty alcohol polyoxyethylene ether, alkyl phenol are poly-
Ethylene oxide ether, castor oil polyoxyethylene ether, nonylphenol polyoxyethylene ether, octyl phenol polyoxyethylene ether, aliphatic alcohol polyethenoxy are poly-
Oxypropylene ether, fatty alcohol polyoxyethylene ether modifier, aliphatic amine polyoxyethylene ether, alkylaryl polyoxyethylene poly-oxygen propylene aether,
EO-PO block polyethers, oleic acid polyoxyethylene, phenethyl phenol polyoxyethylene ether, nonyl phenol phosphate；Such as YUS-110, YUS-
EP60P, Ethylan NS-500LQ (nonionic hydroxyl polyethylene oxide block copolymer), styrene-maleic anhydride copolymer
Sodium salt, 601-P-T, Termul 3015, Termul 1284.
Suspending agent is used to increase the viscosity of decentralized medium in composition the sinking speed to reduce particle or increases particle parent
It is aqueous.In composition pesticide provided by the invention, suspending agent can be selected from following any one or more：Phosphate, Sulfonates, alkane
Base naphthalene sulphonate, carboxylic acid salt high-molecular, polycarboxylate polymeric modified resin, alkyl sulfate, modified alkyl sulfonic acid
Salt, alkyl naphthalene sulfonic acid condensation polymer sodium salt, naphthalene sulfonate (condensation polymer) class, polycarboxylate polymeric dispersant, multi-styrene phenylate
Phosphate dispersant, naphthalenesulfonate formaldehyde condensation compound, APES formaldehyde condensation product sulfonate, lignin sulfonic acid
Salt, white carbon, aluminium-magnesium silicate；For example, Tersperse2500, Tersperse 4894, soybean oil, SP-3266 etc..
Antifoaming agent is used to remove excessive foam in production process.In composition pesticide provided by the invention, antifoaming agent is optional
With GP types antifoaming agent, PE types antifoaming agent, GPES types antifoaming agent, 1522 type antifoaming agent of SAG, organosilicon, polyether-modified silicon, poly- silicon
It is one or more in oxygen alkane.
Antifreezing agent is the substance for reducing the freezing point of composition liquid, improving freezing tolerance.In agriculture provided by the invention
In drug composition, antifreezing agent is selected from following any one or more：Ethylene glycol, propylene glycol, glycerine, butanol, urea.
Binder is for the substance by homogeneity in composition or heterogeneous body surface bonding connection together.In the present invention
In the composition pesticide of offer, ammonium sulfate, sodium carboxymethylcellulose, polyvinylpyrrolidone, starch, poly- second can be selected in binder
It is one or more in enol, methylcellulose, fructose, such as glucose, cornstarch, cyclohexanone.
Thickener improves combination thing liquid for increasing the viscosity of decentralized medium in composition to reduce the sinking speed of particle
The layering of body.In composition pesticide provided by the invention, thickener is selected from following any one or more：Xanthans, poly- second two
Alcohol 4000, Macrogol 6000, gum arabic, gelatin, epoxidized soybean oil.
Film forming agent is used to active ingredient being adhered to the surface of the seed, forms smooth medicine film.In pesticide provided by the invention
In composition, film forming agent can select polyvinyl alcohol, polyvinyl acetate, carboxymethyl cellulose, Arabic gelatin, gelatin, Huang
It is one or more in virgin rubber, such as film forming agent BF308, Lauryl Alcohol ester, film forming agent CMJ-002-02.
PH adjusting agent is used for the acid-base value of regulation composition.In composition pesticide provided by the invention, pH adjusting agent choosing
From following any one or more：Citric acid, sodium bicarbonate, diethylamine, triisopropanolamine, phosphoric acid, glacial acetic acid.
It is further preferred that in the above-mentioned composition pesticide containing cyflumetofen, the carrier is selected from following any
Or it is a variety of：Aluminium-magnesium silicate, aerosil, ammonium sulfate, diatomite, attapulgite, bentonite, kaolin, calcite, cunning
Stone, montmorillonite, calcium carbonate, tripoli, soluble starch, insolubility starch.
Preferably, the above-mentioned composition pesticide containing cyflumetofen also includes：Pigment.
It is further preferred that in the above-mentioned composition pesticide containing cyflumetofen, the pigment is selected from following any
Or it is a variety of：Cinnabar, indigo, iron oxide yellow, alkermes.
Preferably, the dosage form of the above-mentioned composition pesticide containing cyflumetofen is following any：Water dispersible granules, water and milk
Agent, emulsifiable concentrate, wettable powder, suspending agent, seed treatment, soluble powder, granule, oil suspending agent, microcapsule formulations.
Meanwhile the second aspect of the present invention provides the composition pesticide containing cyflumetofen described in first aspect anti-
Control the application in pest.
Wherein, the composition pesticide containing cyflumetofen can directly act on pest or act on its environment,
In habitat or storage areas.In application process, the composition pesticide containing cyflumetofen can be applied to plant stem,
It is one or more in leaf, seed, fruit, root or soil.
Wherein, the plant is preferably that crops (including cereal, veterinary antibiotics etc.), gardening plant, fruit tree and deep woods are planted
Object, further preferably cereal, vegetable crop, such as rice, wheat, corn, Chinese cabbage.Wherein, contain cyflumetofen using described
The mode of composition pesticide can be one or more in impregnating, spray, evaporating, being atomized, broadcasting sowing, brushing etc..
Preferably, in above application, the pest is citrus red mite, blister mite, root-knot nematode, aphid, plant hopper, Ji
Any one of horse.
In conclusion the composition pesticide provided by the invention containing cyflumetofen is compared with prior art, at least have
Following advantageous effect：The active ingredient of the composition pesticide is containing 4- to the 1,3- dioxies of phenoxy-phenoxy methyl structural
Penta cyclics (structure formula (I) compound represented) and cyflumetofen, i.e., compounded by the two, and is examined by testing
It surveys and finds, the drug effect of the composition pesticide is apparently higher than the preventive effect of single dose insecticide ingredient, so reducing the use of composition
Dosage significantly reduces the resistance risk of pest, improves the service efficiency of composition pesticide, so as to increase farming produce
It measures while significantly reducing the pollution to environment.Therefore, the composition pesticide provided by the present invention containing cyflumetofen is being prevented
There is good market potential and wide application prospect in terms of pest.
Specific implementation mode
The present invention is further elaborated With reference to embodiment, but the present invention is not limited to following embodiment party
Formula.
Embodiment 1
The method for calculating the co-toxicity coefficient of compounding agent according to poison exponent calculates the toxicity index and co-toxicity coefficient of medicament
(CTC)。
Theoretical toxicity index (TTI)=∑ (the toxicity index TI of each single dose × percentage of the single dose in mixture)
Experimental judgment foundation：
When CTC≤80, then composition shows as antagonism, when 80<CTC<120, then composition show as summation action,
When CTC >=120, then composition shows as synergistic effect.
By 4- to phenoxy group Phenoxymethyl -2- ethyl -1,3- dioxolanes and cyflumetofen according to 40：1~1：40 weight
Amount than being mixed to get numerous compositions, choose the corresponding composition measuring of wherein several specific weight ratios its to citrus red mite
Toxicity action, test result are as shown in table 1：
Table 1 compares the virulence test result of citrus red mite
Analysis of experimental results：As can be seen from Table 1：
1) 4- to phenoxy group Phenoxymethyl -2- ethyl -1,3- dioxolanes and cyflumetofen 40：1-1：40 weight ratio
In example range, survey toxicity index (ATI) is above toxicity index (TTI).Especially 4- is to phenoxy group Phenoxymethyl -2- second
Base -1,3- dioxolanes and cyflumetofen are 8：1-1：Within the scope of 8 weight ratio, ATI is far above TTI, illustrates synergistic effect
Obviously.
2) 4- to phenoxy group Phenoxymethyl -2- ethyl -1,3- dioxolanes and cyflumetofen 40：1-1：40 weight ratio
In example range, co-toxicity coefficient (CTC) is all higher than 80, and antagonism is not present；4- is to phenoxy group Phenoxymethyl -2- ethyls -1,3-
Dioxolanes and cyflumetofen are 8：1-1：Within the scope of 40 weight ratio, CTC is above 120, has apparent synergistic effect；
Wherein, 4- to phenoxy group Phenoxymethyl -2- ethyls -1,3-dioxolane and cyflumetofen 4：1-1：4 weight ratio range
Interior, CTC highests, synergistic effect is stronger, especially weight ratio ranging from 1：When 1, CTC has reached 178.44, synergistic effect
It is most strong.
3) 4- to phenoxy group Phenoxymethyl -2- ethyl -1,3- dioxolanes and cyflumetofen 1：4-1：40 weight ratio
In example range, survey toxicity index (ATI) is above the toxicity index 950.94 of cyflumetofen.
4) 4- to phenoxy group Phenoxymethyl -2- ethyl -1,3- dioxolanes and cyflumetofen 4：1-1：40 weight ratio
In example range, with the increase of cyflumetofen ratio, to the half lethal concentration (LC of citrus red mite50) decline obviously；4- pairs
Phenoxy group Phenoxymethyl -2- ethyl -1,3- dioxolanes and cyflumetofen are 8：1-1：Within the scope of 40 weight ratio, 4- is to benzene
The LC of oxygroup Phenoxymethyl -2- ethyl -1,3- dioxolanes and cyflumetofen complex composition50Far below exclusive use 4- to benzene
LC when oxygroup Phenoxymethyl -2- ethyl -1,3- dioxolanes50, with LC when exclusive use cyflumetofen50It is suitable or lower,
4- is to phenoxy group Phenoxymethyl -2- ethyl -1,3- dioxolanes and cyflumetofen 1：4-1：Within the scope of 40 weight ratio, group
Close the LC of object50Significantly lower than the LC of cyflumetofen50。
As can be seen that 4- provided by the invention is to phenoxy group Phenoxymethyl -2- ethyls -1,3-dioxolane and cyflumetofen
Composition, when 4- to phenoxy group Phenoxymethyl -2- ethyls -1,3-dioxolane and cyflumetofen 40：1-1：40 weight ratio
In example range, antagonism is not present, and LC can be reduced50；4- is to phenoxy group Phenoxymethyl -2- ethyl -1,3- dioxolanes
With cyflumetofen 40：1-1：Within the scope of 40 weight ratio, there is synergistic effect, 4- is to phenoxy group Phenoxymethyl -2- ethyls -
1,3- dioxolanes and cyflumetofen are 8：1-1：Within the scope of 8 weight ratio, synergistic effect is the most apparent；4- is to phenoxy group benzene
Oxygen methyl -2- ethyl -1,3- dioxolanes and cyflumetofen are 1：4-1：Within the scope of 40 weight ratio, the LC of composition50It is non-
Often low, safety in utilization is improved.
In summary various factors, 4- is to phenoxy group Phenoxymethyl -2- ethyls -1,3-dioxolane and cyflumetofen
Weight ratio is 1：4-1：In the case of 8, there is optimum efficiency.
Embodiment 2
Experiment effect computational methods and experimental judgment foundation：It is same as Example 1.
By 4- to phenoxy group Phenoxymethyl -2- n-propyl -1,3- dioxolanes and cyflumetofen according to 40：1~1：40
Weight ratio is mixed to get numerous compositions, chooses corresponding its poison to blister mite of composition measuring of wherein several specific weight ratios
Force effect, test result are as shown in table 2：
Table 2 compares the virulence test result of blister mite
Analysis of experimental results：As can be seen from Table 2：
1) 4- to phenoxy group Phenoxymethyl -2- n-propyl -1,3- dioxolanes and cyflumetofen 40：1-1：40 weight
In proportional region, survey toxicity index (ATI) is above toxicity index (TTI).Especially 4- to phenoxy group Phenoxymethyl -2- just
Propyl -1,3- dioxolanes and cyflumetofen are 4：1-1：Within the scope of 4 weight ratio, ATI is far above TTI, shows that synergy is made
With apparent.
2) 4- to phenoxy group Phenoxymethyl -2- n-propyl -1,3- dioxolanes and cyflumetofen 20：1-1：20 weight
In proportional region, co-toxicity coefficient (CTC) is all higher than 120, has apparent synergistic effect；Wherein, 4- is to phenoxy group Phenoxymethyl-
2- n-propyl -1,3- dioxolanes and cyflumetofen are 8：1-1：Within the scope of 8 weight ratio, CTC reaches as high as 212.77, increases
Effect effect is most strong.
3) 4- to phenoxy group Phenoxymethyl -2- n-propyl -1,3- dioxolanes and cyflumetofen 1：1-1：40 weight
In proportional region, survey toxicity index (ATI) is above the toxicity index of cyflumetofen.
4) 4- to phenoxy group Phenoxymethyl -2- n-propyl -1,3- dioxolanes and cyflumetofen 4：1-1：4 weight ratio
In example range, with the increase of cyflumetofen ratio, to the half lethal concentration (LC of blister mite50) decline obviously；4- is to benzene oxygen
Base Phenoxymethyl -2- n-propyl -1,3- dioxolanes and cyflumetofen are 8：1-1：Within the scope of 8 weight ratio, 4- is to benzene oxygen
The LC of base Phenoxymethyl -2- n-propyl -1,3- dioxolanes and cyflumetofen complex composition50Far below exclusive use 4- to benzene
LC when oxygroup Phenoxymethyl -2- n-propyl -1,3- dioxolanes50, with LC when exclusive use cyflumetofen50Quite or more
Low, 4- is to phenoxy group Phenoxymethyl -2- n-propyls -1,3-dioxolane and cyflumetofen 1：1-1：40 weight ratio range
It is interior, the LC of composition50Significantly lower than the LC of cyflumetofen50。
As can be seen that 4- provided by the invention is to phenoxy group Phenoxymethyl -2- n-propyls -1,3-dioxolane and fourth fluorine mite
Ester is 40：1-1：Within the scope of 40 weight ratio, there is synergistic effect, and LC can be reduced50；4- is to phenoxy group Phenoxymethyl-
2- n-propyl -1,3- dioxolanes and cyflumetofen are 4：1-1：Within the scope of 4 weight ratio, synergistic effect is the most apparent；4-
To phenoxy group Phenoxymethyl -2- n-propyl -1,3- dioxolanes and cyflumetofen 1：1-1：Within the scope of 40 weight ratio, group
Close the LC of object50Very low, the safety used is improved.
In summary various factors, 4- is to phenoxy group Phenoxymethyl -2- n-propyls -1,3-dioxolane and cyflumetofen
Weight ratio be 1：1-1：In the case of 4, there is optimum efficiency.
Embodiment 3
Experiment effect computational methods and experimental judgment foundation：It is same as Example 1.
By 4- to phenoxy group Phenoxymethyl -2- ethyl -1,3- dioxolanes and cyflumetofen according to 40：1~1：40 weight
Amount chooses corresponding its poison to root-knot nematode of composition measuring of wherein several specific weight ratios than being mixed to get numerous compositions
Force effect, test result are as shown in table 3：
Table 3 compares the virulence test result of root-knot nematode
Analysis of experimental results：As can be seen from Table 3：
1) 4- to phenoxy group Phenoxymethyl -2- ethyl -1,3- dioxolanes and cyflumetofen 40：1-1：40 weight ratio
In example range, survey toxicity index (ATI) is above toxicity index (TTI).Especially 4- is to phenoxy group Phenoxymethyl -2- second
Base -1,3- dioxolanes and cyflumetofen are 20：1-1：Within the scope of 8 weight ratio, ATI is far above TTI, shows synergistic effect
Obviously.
2) 4- to phenoxy group Phenoxymethyl -2- ethyl -1,3- dioxolanes and cyflumetofen 40：1-1：8 weight ratio
In example range, co-toxicity coefficient (CTC) is all higher than 120, has apparent synergistic effect；Wherein, 4- is to phenoxy group Phenoxymethyl -2-
Ethyl -1,3- dioxolanes and cyflumetofen are 20：1-1：Within the scope of 8 weight ratio, CTC reaches as high as 195.47, synergy
Effect is most strong.
3) 4- to phenoxy group Phenoxymethyl -2- ethyl -1,3- dioxolanes and cyflumetofen 1：4-1：20 weight ratio
In example range, survey toxicity index (ATI) is above the toxicity index of cyflumetofen.
4) 4- to phenoxy group Phenoxymethyl -2- ethyl -1,3- dioxolanes and cyflumetofen 4：1-1：4 weight ratio
In range, with the increase of cyflumetofen ratio, to the half lethal concentration (LC of root-knot nematode50) decline obviously；4- is to benzene oxygen
Base Phenoxymethyl -2- ethyl -1,3- dioxolanes and cyflumetofen are 1：1-1：Within the scope of 20 weight ratio, 4- is to phenoxy group
The LC of Phenoxymethyl -2- ethyl -1,3- dioxolanes and cyflumetofen complex composition50Far below exclusive use 4- to phenoxy group
LC when Phenoxymethyl -2- ethyl -1,3- dioxolanes50, with LC when exclusive use cyflumetofen50It is suitable or lower, 4- pairs
Phenoxy group Phenoxymethyl -2- ethyl -1,3- dioxolanes and cyflumetofen are 1：4-1：Within the scope of 20 weight ratio, composition
LC50Significantly lower than the LC of cyflumetofen50。
As can be seen that 4- provided by the invention is to phenoxy group Phenoxymethyl -2- ethyls -1,3-dioxolane and cyflumetofen
40：1-1：Within the scope of 40 weight ratio, there is synergistic effect, and LC can be reduced50；4- is to phenoxy group Phenoxymethyl -2-
Ethyl -1,3- dioxolanes and cyflumetofen are 20：1-1：Within the scope of 8 weight ratio, synergistic effect is the most apparent；4- is to benzene
Oxygroup Phenoxymethyl -2- ethyl -1,3- dioxolanes and cyflumetofen are 1：4-1：Within the scope of 20 weight ratio, composition
LC50Very low, the safety used is improved.
In summary various factors, 4- is to phenoxy group Phenoxymethyl -2- ethyls -1,3-dioxolane and cyflumetofen
Weight ratio is 1：4-1：In the case of 8, there is optimum efficiency.
It is worth noting that in the composition pesticide of the present invention containing cyflumetofen, it is described containing 4- to benzene oxygen
The 1,3- dioxolane compounds of phenoxyl methyl structural for example can also be 4- to phenoxy group Phenoxymethyl -2- isopropyls
Base -1,3- dioxolanes, 4- are to phenoxy group Phenoxymethyl -2- cyclopenta -1,3- dioxolanes, 4- to phenoxy group Phenoxymethyl -
2- phenyl -1,3- dioxolanes, 4- are to phenoxy group Phenoxymethyl -2- cyclopropyl -1,3- dioxolanes etc..
In addition, specific Formulation Example is as follows：
Embodiment 4
Prepare suspending agent
The 4- that the active constituent content for preparing composition is 30% is to phenoxy group Phenoxymethyl -2- ethyl -1,3- dioxies penta
The suspending agent of ring and cyflumetofen, on the basis of the total weight of suspending agent, including：
Will after the above components are mixed, obtained 30% 4- is to phenoxy group Phenoxymethyl -2- ethyls -1,3-dioxolane fourth
Fluorine mite ester suspending agent.
Embodiment 5
Prepare wettable powder
The 4- that the active constituent content for preparing composition is 60% is to phenoxy group Phenoxymethyl -2- cyclopenta -1,3- dioxies
The wettable powder of penta ring and cyflumetofen, on the basis of the total weight of wettable powder, including：
After mixing the above components evenly, then through air-flow crushing, 60% 4- is obtained to phenoxy group Phenoxymethyl -2- rings
Amyl -1,3- dioxolanes cyflumetofen wettable powders.
Embodiment 6
Prepare missible oil
The 4- that the active constituent content for preparing composition is 30% is to phenoxy group Phenoxymethyl -2- normal-butyl -1,3- dioxies
The missible oil of penta ring and cyflumetofen, on the basis of the total weight of missible oil, including：
Said components are mixed, transparency liquid is stirred until homogeneous, obtain 30% 4- to phenoxy group Phenoxymethyl -2- just
Butyl -1,3- dioxolanes cyflumetofen missible oil.
Embodiment 7
Prepare water dispersible granules
The 4- that the active constituent content for preparing composition is 50% is to phenoxy group Phenoxymethyl -2- ethyl -1,3- dioxies penta
The water dispersible granules of ring and cyflumetofen, on the basis of the total weight of water dispersible granules, including：
After mixing the above components evenly, through air-flow crushing at wettable powder, adds a certain amount of water mixing extruding and make
Grain；Screening is finally dried, obtained 50% 4- is to phenoxy group Phenoxymethyl -2- ethyls -1,3-dioxolane fourth fluorine mite
Ester water dispersible granules.
Embodiment 8
Prepare microcapsule formulations
20% 4- is prepared to phenoxy group Phenoxymethyl -2- ethyls -1,3-dioxolane and cyflumetofen microcapsule formulations,
In, inner core suspending agent includes the component of following weight ratio on the basis of the total weight of microcapsule formulations in the microcapsule formulations：
4- is to phenoxy group Phenoxymethyl -2- ethyl -1,3- dioxolanes 8%, cyflumetofen 12%, methanol 15%, emulsification
Agent 25%；
Wherein, the emulsifier is 25%YUS (D935).
The step of preparation includes：
Step 1, after preparing inner core suspending agent, pollopas is added and is mixed as wall material, the speed of stirring is
The time of 2000r/min, stirring are 30min, wherein the weight ratio of the inner core suspending agent and pollopas is 5：1, (i.e.
Core wall ratio is 5：1)；
Step 2, auxiliary agent and carrier below are added after completing above-mentioned steps 1, wherein the additive amount of auxiliary agent and carrier with
On the basis of the total weight of microcapsule formulations, include the component of following weight ratio：
KY (518) 2.0%, lauryl sodium sulfate 3.0%, glucose 0.5%, xanthans 0.15%, benzoic acid
0.3%, antifoaming agent (SAG 1572) 0.1% and addition pure water supply 100%, obtain 20% required 4- to phenoxy group benzene
Oxygen methyl -2- ethyl -1,3- dioxolanes and cyflumetofen microcapsule formulations.
Embodiment 9
Prepare seed treatment
The 4- of preparation 50% is to phenoxy group Phenoxymethyl -2- isopropyl -1,3- dioxolanes and cyflumetofen seed treatment
Agent, wherein on the basis of the total weight of seed treatment, include the component of following weight ratio：
4- is to phenoxy group Phenoxymethyl -2- isopropyl -1,3- dioxolanes 20%, cyflumetofen 30%, KY (536)
4.0%, KY (555) 2.0%, aluminium-magnesium silicate 0.8%, xanthans 0.2%, triethanolamine 0.5%, propylene glycol 5.0%, film forming agent
0.8%, mill base 3.0%, pure water supply 100%；
Wherein, the film forming agent is BF308；The mill base is FGR131.
50% required 4- is obtained to phenoxy group Phenoxymethyl -2- isopropyls -1,3- two after above-mentioned component is mixed
Butyl oxide link and cyflumetofen seed treatment.
Embodiment 10
Prepare oil suspending agent
The 4- that the active constituent content for preparing composition is 30% is to phenoxy group Phenoxymethyl -2- n-propyl -1,3- dioxies
The oil suspending agent of penta ring and cyflumetofen, on the basis of the total weight of oil suspending agent, including：
Said components are mixed and are sheared, and after sand mill is ground, 30% 4- are made to phenoxy group Phenoxymethyl -2- just
Propyl -1,3- dioxolanes cyflumetofen oil suspending agents.
Embodiment 11
Prepare aqueous emulsion
The 4- that the active constituent content for preparing composition is 20% is to phenoxy group Phenoxymethyl -2- cyclopenta -1,3- dioxies
The aqueous emulsion of penta ring and cyflumetofen, on the basis of the total weight of aqueous emulsion, including：
By after the above components are mixed obtained 20% 4- to phenoxy group Phenoxymethyl -2- cyclopenta -1,3- dioxolanes
Cyflumetofen aqueous emulsion.
Embodiment 12
Field control effectiveness test
Inventor has also carried out the test of pesticide effectiveness respectively, and test result is as shown in the table：
The preventive effect table of comparisons of the table 4 to citrus red mite
The preventive effect table of comparisons of the table 5 to blister mite
In conclusion the present invention by containing 4- to the 1,3-dioxolane class compound of phenoxy-phenoxy methyl structural with
The preventive effect when drug effect for the composition pesticide that cyflumetofen is compounded is apparently higher than using single-dose product, and lasting effect
It is excellent, therefore, it can achieve the effect that desinsection using less dosage, so as to substantially reduce the drug resistance wind of pest
Danger.
Specific embodiments of the present invention are described in detail above, but it is intended only as example, the present invention is simultaneously unlimited
It is formed on particular embodiments described above.To those skilled in the art, it is any to the equivalent modifications that carry out of the present invention and
It substitutes also all among scope of the invention.Therefore, without departing from the spirit and scope of the invention made by impartial conversion and
Modification, all should be contained within the scope of the invention.
Claims (10)
1. a kind of composition pesticide containing cyflumetofen, including component A and B component, which is characterized in that
The component A is to have following structure the compound of formula (I)：
Wherein, R is selected from following any：Alkyl group, naphthenic base, alkenyl and aryl；
The B component is cyflumetofen；
Also, the weight ratio of the component A and the B component is 40：1~1：40.
2. the composition pesticide according to claim 1 containing cyflumetofen, which is characterized in that R is selected from following any：
The alkyl group of C1-C10, the naphthenic base of C3-C10, the aryl of C6-C14.
3. the composition pesticide according to claim 1 containing cyflumetofen, which is characterized in that also include：Auxiliary agent or/and
Carrier.
4. the composition pesticide according to claim 3 containing cyflumetofen, which is characterized in that the auxiliary agent is selected from following
It is any one or more：Wetting agent, dispersant, emulsifier, suspending agent, antifoaming agent, antifreezing agent, binder, thixotropic agent, thickener,
Film forming agent, pH adjusting agent.
5. the composition pesticide according to claim 3 containing cyflumetofen, which is characterized in that the carrier is selected from following
It is any one or more：Aluminium-magnesium silicate, aerosil, ammonium sulfate, diatomite, attapulgite, bentonite, kaolin, Fang Xie
Stone, talcum, montmorillonite, calcium carbonate, tripoli, soluble starch, insolubility starch.
6. the composition pesticide according to claim 1 containing cyflumetofen, which is characterized in that also include：Pigment.
7. the composition pesticide according to claim 6 containing cyflumetofen, which is characterized in that the pigment is selected from following
It is any one or more：Cinnabar, indigo, iron oxide yellow, alkermes.
8. the composition pesticide according to claim 1 containing cyflumetofen, which is characterized in that described to contain cyflumetofen
Composition pesticide dosage form be it is following any：Water dispersible granules, aqueous emulsion, emulsifiable concentrate, wettable powder, suspending agent, kind
Subprocessing agent, soluble powder, granule, oil suspending agent, microcapsule formulations.
9. application of the composition pesticide according to claim 1 containing cyflumetofen in pest control.
10. application according to claim 9, which is characterized in that the pest is citrus red mite, blister mite, root knot line
Any one of worm, aphid, plant hopper, thrips.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810247142.6A CN108450466A (en) | 2018-03-23 | 2018-03-23 | A kind of composition pesticide containing cyflumetofen and its application in pest control |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810247142.6A CN108450466A (en) | 2018-03-23 | 2018-03-23 | A kind of composition pesticide containing cyflumetofen and its application in pest control |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4087581A (en) * | 1974-09-23 | 1978-05-02 | Champion International Corporation | Opacifying super-particles |
| CN1446196A (en) * | 2000-08-11 | 2003-10-01 | 大塚化学控股株式会社 | Acylacetonitriles, process for preparation thereof and miticides containing the same |
| CN104115833A (en) * | 2014-06-12 | 2014-10-29 | 广东中迅农科股份有限公司 | Insect and mite killing composition containing pyriproxyfen and cyflumetofen |
-
2018
- 2018-03-23 CN CN201810247142.6A patent/CN108450466A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4087581A (en) * | 1974-09-23 | 1978-05-02 | Champion International Corporation | Opacifying super-particles |
| CN1446196A (en) * | 2000-08-11 | 2003-10-01 | 大塚化学控股株式会社 | Acylacetonitriles, process for preparation thereof and miticides containing the same |
| CN104115833A (en) * | 2014-06-12 | 2014-10-29 | 广东中迅农科股份有限公司 | Insect and mite killing composition containing pyriproxyfen and cyflumetofen |
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