CN108434154A - 用于治疗疾病的唑来膦酸或相关化合物的经口施用组合物 - Google Patents

用于治疗疾病的唑来膦酸或相关化合物的经口施用组合物 Download PDF

Info

Publication number
CN108434154A
CN108434154A CN201810150156.6A CN201810150156A CN108434154A CN 108434154 A CN108434154 A CN 108434154A CN 201810150156 A CN201810150156 A CN 201810150156A CN 108434154 A CN108434154 A CN 108434154A
Authority
CN
China
Prior art keywords
zoledronic acid
oral
dosage
purposes according
disodium salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810150156.6A
Other languages
English (en)
Chinese (zh)
Inventor
赫里奥特·塔布提奥
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Antecip Bioventures II LLC
Original Assignee
Antecip Bioventures II LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US14/063,979 external-priority patent/US8802658B2/en
Application filed by Antecip Bioventures II LLC filed Critical Antecip Bioventures II LLC
Publication of CN108434154A publication Critical patent/CN108434154A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN201810150156.6A 2013-10-25 2014-08-08 用于治疗疾病的唑来膦酸或相关化合物的经口施用组合物 Pending CN108434154A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US14/063,979 2013-10-25
US14/063,979 US8802658B2 (en) 2012-05-14 2013-10-25 Compositions for oral administration of zoledronic acid or related compounds for treating disease
US14/279,241 2014-05-15
US14/279,241 US20140249317A1 (en) 2012-05-14 2014-05-15 Compositions for oral administration of zoledronic acid or related compounds for treating disease
CN201480069491.3A CN105960240B (zh) 2013-10-25 2014-08-08 用于治疗疾病的唑来膦酸或相关化合物的经口施用组合物

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201480069491.3A Division CN105960240B (zh) 2013-10-25 2014-08-08 用于治疗疾病的唑来膦酸或相关化合物的经口施用组合物

Publications (1)

Publication Number Publication Date
CN108434154A true CN108434154A (zh) 2018-08-24

Family

ID=52993341

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201810150156.6A Pending CN108434154A (zh) 2013-10-25 2014-08-08 用于治疗疾病的唑来膦酸或相关化合物的经口施用组合物
CN201480069491.3A Active CN105960240B (zh) 2013-10-25 2014-08-08 用于治疗疾病的唑来膦酸或相关化合物的经口施用组合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201480069491.3A Active CN105960240B (zh) 2013-10-25 2014-08-08 用于治疗疾病的唑来膦酸或相关化合物的经口施用组合物

Country Status (12)

Country Link
EP (1) EP3060220A4 (ko)
JP (6) JP6166471B2 (ko)
KR (3) KR101739244B1 (ko)
CN (2) CN108434154A (ko)
AU (2) AU2014340649C1 (ko)
CA (1) CA2928350C (ko)
HK (1) HK1257400A1 (ko)
IL (2) IL245287A0 (ko)
MX (1) MX2016005396A (ko)
MY (1) MY176246A (ko)
SG (3) SG10201609548UA (ko)
WO (1) WO2015060924A1 (ko)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11654152B2 (en) 2012-05-14 2023-05-23 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating disease
US10493085B2 (en) 2012-05-14 2019-12-03 Antecip Bioventures Ii Llc Neridronic acid and other bisphosphonates for treating complex regional pain syndrome and other diseases
US10413561B2 (en) 2012-05-14 2019-09-17 Antecip Bioventures Ii Llc Neridronic acid and other bisphosphonates for treating complex regional pain syndrome and other diseases
US9999629B2 (en) 2012-05-14 2018-06-19 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US10413560B2 (en) 2012-05-14 2019-09-17 Antecip Bioventures Ii Llc Dosage forms for oral administration of zoledronic acid or related compounds for treating disease
US10463682B2 (en) 2012-05-14 2019-11-05 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating low back pain
US10350227B2 (en) 2012-05-14 2019-07-16 Antecip Bioventures Ii Llc Neridronic acid for treating complex regional pain syndrome
US10016445B2 (en) 2012-05-14 2018-07-10 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US9956238B2 (en) 2014-05-15 2018-05-01 Antecip Bioventures Ii Llc Compositions for administration of zoledronic acid or related compounds for treating low back pain
AU2014340649C1 (en) * 2013-10-25 2017-05-18 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating disease
EP3533923B1 (en) 2016-10-28 2024-05-15 Mitsubishi Chemical Corporation Sizing agent for carbon fibers, aqueous dispersion of sizing agent for carbon fibers, and sizing agent-adhered carbon fiber bundle

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104349781A (zh) * 2012-05-14 2015-02-11 安泰赛普生物风投二代有限责任公司 用于减轻炎性疼痛或相关病症的包含唑来膦酸或相关化合物的组合物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000038693A1 (fr) * 1998-12-25 2000-07-06 Toray Industries, Inc. Inhibiteurs de la production d'interleukine-6
GB0029111D0 (en) * 2000-11-29 2001-01-10 Novartis Ag Organic compounds
PL363507A1 (en) * 2001-05-02 2004-11-29 Novartis Ag Pharmaceutical uses of bisphosphonates
US7875597B2 (en) * 2002-07-24 2011-01-25 New York University Treatment of spinal mechanical pain
CA2501381A1 (en) * 2002-10-15 2004-04-29 Novartis Ag Method of administering bisphosphonates
ES2322592T3 (es) * 2003-07-03 2009-06-23 Teva Pharmaceutical Industries Ltd. Formas cristalinas de acido zoledronico, formas cristlinas de la sal sodica de zoledronato, sal sodica de zoledronato amorfa y procedimientos para su preparacion.
AR046773A1 (es) * 2003-12-23 2005-12-21 Novartis Ag Formulaciones farmaceuticas de bisfosfonatos
AU2010278860B2 (en) * 2009-07-31 2016-05-26 Thar Pharma, Llc Crystallization method and bioavailability
ES2638072T3 (es) * 2010-02-06 2017-10-18 Grünenthal GmbH Método de cristalización y biodisponibilidad
US9340565B2 (en) * 2010-11-24 2016-05-17 Thar Pharmaceuticals, Inc. Crystalline forms
AU2014340649C1 (en) * 2013-10-25 2017-05-18 Antecip Bioventures Ii Llc Compositions for oral administration of zoledronic acid or related compounds for treating disease

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104349781A (zh) * 2012-05-14 2015-02-11 安泰赛普生物风投二代有限责任公司 用于减轻炎性疼痛或相关病症的包含唑来膦酸或相关化合物的组合物

Also Published As

Publication number Publication date
JP6802245B2 (ja) 2020-12-16
CA2928350A1 (en) 2015-04-30
JP2016534081A (ja) 2016-11-04
IL254123A0 (en) 2017-10-31
JP2021028343A (ja) 2021-02-25
EP3060220A4 (en) 2017-05-31
CN105960240A (zh) 2016-09-21
AU2014340649C1 (en) 2017-05-18
JP2017200941A (ja) 2017-11-09
IL245287A0 (en) 2016-06-30
AU2017200832A1 (en) 2017-03-02
HK1257400A1 (zh) 2019-10-18
JP2024040304A (ja) 2024-03-25
KR20160062177A (ko) 2016-06-01
MX2016005396A (es) 2017-03-01
SG10201800001VA (en) 2018-02-27
JP2019059771A (ja) 2019-04-18
SG11201603042TA (en) 2016-05-30
CA2928350C (en) 2018-01-09
AU2014340649B2 (en) 2016-11-17
JP6166471B2 (ja) 2017-07-19
KR101975687B1 (ko) 2019-05-07
JP7136487B2 (ja) 2022-09-13
KR20170058444A (ko) 2017-05-26
WO2015060924A1 (en) 2015-04-30
JP6453387B2 (ja) 2019-01-16
MY176246A (en) 2020-07-24
KR101739244B1 (ko) 2017-05-23
CN105960240B (zh) 2018-04-20
KR20190009428A (ko) 2019-01-28
EP3060220A1 (en) 2016-08-31
JP2022162105A (ja) 2022-10-21
SG10201609548UA (en) 2016-12-29

Similar Documents

Publication Publication Date Title
CN105960240B (zh) 用于治疗疾病的唑来膦酸或相关化合物的经口施用组合物
AU2018214132B2 (en) Compositions comprising zoledronic acid or related compounds for relieving inflammatory pain and related conditions
US9616077B2 (en) Dosage forms for oral administration of zoledronic acid or related compounds for treating disease
US20150057250A1 (en) Inhibitors of osteoclast activity for treating arthritis
AU2014340649A1 (en) Compositions for oral administration of zoledronic acid or related compounds for treating disease
CN106456610A (zh) 用于疼痛的破骨细胞抑制剂
WO2016172453A1 (en) Pharmacodynamic effects after oral administration of zoledronic acid or related compounds

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1257400

Country of ref document: HK

WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20180824