CN108421133A - Drug delivery device and its transmission mechanism - Google Patents

Drug delivery device and its transmission mechanism Download PDF

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Publication number
CN108421133A
CN108421133A CN201810129822.8A CN201810129822A CN108421133A CN 108421133 A CN108421133 A CN 108421133A CN 201810129822 A CN201810129822 A CN 201810129822A CN 108421133 A CN108421133 A CN 108421133A
Authority
CN
China
Prior art keywords
transmission body
transmission
rotation axis
rotation
rotated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810129822.8A
Other languages
Chinese (zh)
Inventor
黄霖
李鑫
罗志华
刘宇程
沈玉娟
刘智勇
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medtronic Inc
Original Assignee
Medtronic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic Inc filed Critical Medtronic Inc
Priority to CN201810129822.8A priority Critical patent/CN108421133A/en
Publication of CN108421133A publication Critical patent/CN108421133A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006Having specific accessories
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • A61M2205/3334Measuring or controlling the flow rate

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The invention discloses a kind of drug delivery device and its transmission mechanisms.Wherein, the transmission mechanism includes:Rotation axis, for being rotated under the action of driving force;First transmission body coordinates with the rotation axis and is rotated with the rotation of the rotation axis;Second transmission body coordinates with first transmission body and is rotated with the rotation of the first transmission body;Wherein, first transmission body is configured as with the rotation axis:In the case where not applying the driving force, first transmission body responds the rotation of second transmission body and along the axial movement of the rotation axis.Related embodiment using the present invention is conducive to improve precision in drug administration.

Description

Drug delivery device and its transmission mechanism
Technical field
The present invention relates to the fluid delivery fields being administered to user, more particularly, be related to a kind of drug delivery device and its Transmission mechanism.
Background technology
Diabetes are a kind of metabolic diseases characterized by hyperglycemia.Hyperglycemia is typically due to defect of insulin secretion Or its biological effect is impaired, or both comprehensive function cause.Long-standing hyperglycemia can cause multiple in diabetic's body The chronic lesion of organ (for example, eye, kidney, heart, blood vessel, nervous system etc.), dysfunction.
Diabetes clinical diagnosis can be divided into type 1 diabetes and diabetes B.Type 1 diabetes, also referred to as insulin-dependent Diabetes, patient condition typically occur in child or adolescent's period, are a kind of diseases by congenital familial inheritance.1 type glycosuria Disease belongs to a kind of autoimmune disease, and the immune system of body is made attack to the β cells for producing insulin in vivo, finally led Cause can not produce insulin in vivo.This kind of patient needs the insulin of injection of exogenous to carry out the blood glucose level in control volume.1 type sugar Urine patient generally requires 24 hours carrying electronic formula insulin pump in treatment, for example, Medtronic Minimed series insulin pumps.2 Patients with type Ⅰ DM, also referred to as Non-Insulin Dependent Diabetes Mellitus, general patient are adult, especially obese people, and illness can be led Cause is become thin.The possible cause of disease includes:Insulin resistance prevents body from insulin is efficiently used;The reduction of insulin secretion, It cannot be satisfied needed for body.The diabetes B patient of early stage can be by the mode of making the life better (for example, healthy diet, appropriate fortune Dynamic, safe fat-reducing gives up smoking and avoids secondhand smoke etc.) it controls, or even cure diabetes.Most of diabetes B patient Ke Tong Oral hypoglycemic agents help is crossed to control body blood glucose level or control blood glucose level by interim insulin injection.
Traditional drug delivery device generally comprises reusable part and consumable portion for attaching and pump (patch pump) (that is, not reusable part).Gear-box in the reusable part via output gear output from driver in future driving force to Rack transmits, and the rack belongs to the consumable portion.Before assembling the reusable part and consumable portion, Yi Shenghuo Liquid reservoir in consumable portion is full of liquid by patient, and piston and rack are pushed into setting position.However, the attaching pump is in group After the completion of dress, output gear and rack are generally difficult to perfect engagement, this results in the incorrect deliveries of liquid even to deliver failure.
Invention content
In order to solve the defect present in existing drug delivery device, a kind of drug delivery device of embodiment of the present invention offer and its biography Motivation structure is conducive to accurately controlling for administration.
On the one hand, a kind of transmission mechanism of drug delivery device is provided according to an embodiment of the invention, including:
Rotation axis, for being rotated under the action of driving force;
First transmission body coordinates with the rotation axis and is rotated with the rotation of the rotation axis;
Second transmission body coordinates with first transmission body and is rotated with the rotation of the first transmission body;
Wherein, first transmission body is configured as with the rotation axis:In the case where not applying the driving force, institute It states the first transmission body and responds the rotation of second transmission body and along the axial movement of the rotation axis.
On the other hand, a kind of transmission mechanism of drug delivery device is provided according to an embodiment of the invention, including:
Rotation axis, for being rotated under the action of driving force;
First transmission body coordinates with the rotation axis and is rotated with the rotation of the rotation axis;
It is driven clamp mechanism, is coordinated with first transmission body, and has and is rotated with the rotation of first transmission body Output gear;
Piston impeller coordinates with the output gear and is moved along its length with the rotation of the output gear To push piston;
Wherein, first transmission body can respond the output gear and the piston impeller from non-engagement state to The variation of meshing state and along the axial movement of the rotation axis.
Correspondingly, a kind of drug delivery device is provided according to an embodiment of the invention, including:
Drive system, for providing driving force;
Transmission system, for transmitting the driving force under the driving of the drive system;
Liquid reservoir is used for fluid storage;
Piston is located in the liquid reservoir, is used under the action of the driving force that the transmission system is transmitted, by institute State the fluid discharge in liquid reservoir;
Wherein, the transmission system includes the transmission mechanism provided such as aforementioned any aspect.
Using various embodiments of the present invention, along described turn by responding the rotation of second transmission body by making the first transmission body The axial movement of moving axis can be reduced or eliminated gap caused by the incomplete engagement between tooth, be conducive to the accurate of administration Control.
Description of the drawings
Fig. 1 shows a kind of structural schematic diagram of the transmission mechanism of according to embodiments of the present invention 1 drug delivery device;
Fig. 2 shows a kind of structural schematic diagrams of the transmission mechanism of according to embodiments of the present invention 2 drug delivery device;
Fig. 3 shows a kind of structural schematic diagram of the transmission mechanism of drug delivery device according to inventive embodiments 2;
Fig. 4 shows a kind of structural schematic diagram of according to embodiments of the present invention 3 drug delivery device.
Specific implementation mode
It is described in detail to various aspects of the present invention below in conjunction with the drawings and specific embodiments.Wherein, many institute's weeks Structure, component and its mutual connection, link or the operation known are not shown or do not elaborate.Also, it is described Component, structure or function can in any way combine in one or more embodiments.Those skilled in the art answer Work as understanding, following various embodiments are served only for the protection domain for example, and is not intended to limit the present invention.It can also hold Readily understood, component, structure, unit or step in each embodiment described herein and shown in the drawings can be matched by various differences It sets and is combined and designs.It can also be readily appreciated that, although may be only in some embodiments to specific names, term, range Etc. explaining, but the explanation is equally applicable to other embodiments, unless stated otherwise.
【Embodiment 1】
The present embodiment provides a kind of transmission system of drug delivery device, which for example can be applied to inject to patient In the attaching pump (patch pump) of liquid.Generally speaking, the transmission system includes rotation axis, the first transmission body and the second biography Kinetoplast.It is specifically described below.
In the present embodiment, rotation axis under the action of driving force for rotating, and illustratively, the driving force is by motor It provides.First transmission body coordinates with the rotation axis and is rotated with the rotation of the rotation axis.Second transmission body and first Transmission body coordinates and is rotated with the rotation of the first transmission body.Wherein, first transmission body is configured with the rotation axis For:In the case where not applying the driving force, first transmission body responds the rotation of second transmission body and along described The axial movement of rotation axis.
Fig. 1 shows the structural schematic diagram of according to embodiments of the present invention 1 transmission system.Referring to Fig.1, as of the invention real A kind of realization method of example 1 is applied, rotation axis 10 rotates under the action of driving force, and the first transmission body 20 has worm screw, and second passes Kinetoplast 30 then has the worm gear coordinated with the worm screw.
As shown in Figure 1, the first transmission body 20 in the rotation with the rotation axis 10 can rotate while can be along described The mode of the axial movement of rotation axis is socketed on rotation axis 10.In this way, in response to by 30 lateral first transmission body of the second transmission body The power that 20 sides apply, the first transmission body 20 can be along the axial movement of rotation axis 10.
In fluid delivery field, existing drug delivery device is susceptible to wheel and rack (for pushing piston) and not exclusively nibbles The case where conjunction, being administered can cause dosage to control the defects of inaccurate at this time.And the biography for using the embodiment of the present invention 1 to provide Motivation structure can then eliminate the state that wheel and rack not exclusively engages automatically, to improve the accuracy of administration control.
【Embodiment 2】
Fig. 2 provides the structural schematic diagram of according to embodiments of the present invention 2 transmission mechanism for drug delivery device.With reference to figure 2, the transmission mechanism in addition to including rotation axis 10 as described in example 1 above, the first transmission body 20, the second transmission body 30 it Outside, further include structure described below.
As depicted in figs. 1 and 2, at least one end setting in first transmission body 20 in itself axial both ends is useful Restore after the axial movement of the rotation axis 10 to the return unit 40 of setting position in making first transmission body 20.Using this Design, when the power applied by 30 lateral first transmission body, 20 side of the second transmission body disappears, under the action of return unit 40, first Transmission body 20 is restored to setting position to facilitate the reuse of the transmission mechanism.
Illustratively, the return unit 40 is elastic component (for example, spring or tension spring).One end position of the elastic component 40 It is fixed, for example, the one end is maintained at the circumference residing for fixed position or fixed position in the axial direction of rotation axis 10;The elastic component 40 other end is then abutted or is connect with the first transmission body 20.
As shown in Figures 2 and 3, the transmission mechanism includes output gear 50 and piston impeller 60 (for example, rack).Its In, the output gear 50 is rotated with the second transmission body 30 with merging with the rotation of the second transmission body 30;The piston pushes Part 60 coordinates with the output gear 50 and is moved along its length to push piston with the rotation of the output gear 50 P.Illustratively, the output gear 50 and second transmission body 30 rotate synchronously, the two can be fixedly connected or one at Type, combination can be as subordinate's transmission mechanism of first transmission body, and is properly termed as transmission clamp mechanism.It is exemplary Ground, the piston impeller 60 are rack, the transmission for engaging and carrying out power with the output gear 50.
Optionally, in a kind of realization method of the present embodiment 2, first transmission body 20 is axial along rotation axis 10 Displacement distance is slightly larger than the tooth pitch of the piston impeller 60.
Optionally, in a kind of realization method of the present embodiment, as shown in figure 3, in output gear 50 and piston impeller Being arranged in 60 the two makes the unilateral chamfering A of 50 directional rotating of the output gear when the two not exclusively engages.Based on described defeated Go out the directional rotating of gear 50, can elastic component 40 only correspondingly be set in one end of the first transmission body 20, and by described the One transmission body 20 is limited to smaller along the moving range of the rotation axis 10.Using the transmission mechanism of this design, output gear 50 under the action of piston impeller 60 happens is that directional rotating rather than the uncertain rotation in direction, this not only contributes to keep away Accidentally laxative is to improve the safety of administration for fault-avoidance, in addition, also helping the densification for realizing the transmission mechanism.
The transmission mechanism provided using the present embodiment 2 is not exclusively engaged in piston impeller 60 with 50 the two of output gear The power applied from the second impeller 30 to the first impeller 20 generated under (there is gap) state, passes through the first impeller 20 It is eliminated along the axial movement of rotation axis 10, to eliminate the gap.In other words, the first transmission body 20 can respond described Output gear 50 is with the piston impeller 50 from non-engagement state to the variation of meshing state and along the axis of the rotation axis 10 It is advantageously implemented to movement to eliminate existing gap when both piston impeller 60 and output gear 50 not exclusively engage Dosage accurately controls.
【Embodiment 3】
The embodiment of the present invention also provides a kind of drug delivery device, and with reference to Fig. 4, the drug delivery device includes that drive system (is not schemed Show), transmission system 410, liquid reservoir 420 and piston.Wherein, the drive system is for providing driving force, for example, the driving System is motor-driven system.The transmission system 410 then transmits driving force under the driving of the drive system.The reservoir Device 420 is used for fluid storage.The piston is located in the liquid reservoir 420, described in being transmitted in the transmission system 410 Under the action of driving force, the fluid in the liquid reservoir 420 is discharged.
In the present embodiment, the transmission system 410 includes embodiment described previously or the biography that its realization method is provided Motivation structure, relevant gear, Zhou Deng mechanisms can be set in gear-box (not shown), and use can also be integrally arranged in drug delivery device In the shell for protecting and being attached at human body.About the detailed description of the transmission mechanism, please refer to above, it is no longer superfluous herein It states.And the drug delivery device for using the embodiment of the present invention 3 to provide, the accuracy of administration control can be improved, is also not repeated herein Explanation.
Multiple embodiments according to the present invention are described in detail above in association with attached drawing.Those skilled in the art should Understand, component, mechanism in various embodiments etc. may be used reasonable manner and be combined.Certainly, pass through dependency structure Combination, the drive system and fluid infusion apparatus of other embodiments of the present invention can also have above-mentioned multiple advantages simultaneously. Those skilled in the art are based on technology provided by the invention and design philosophy, carry out combination, increase and replacement of feature etc., This is all belonged to the scope of protection of the present invention.
The term and wording used in description of the invention is just to for example, be not intended to constitute restriction.Ability Field technique personnel should be appreciated that under the premise of not departing from the basic principle of disclosed embodiment, to the above embodiment In each details can carry out various change.Therefore, the scope of the present invention is only determined by claim, in the claims, unless It is otherwise noted, all terms should be understood by the broadest rational meaning.

Claims (10)

1. a kind of transmission mechanism of drug delivery device, which is characterized in that including:
Rotation axis, for being rotated under the action of driving force;
First transmission body coordinates with the rotation axis and is rotated with the rotation of the rotation axis;
Second transmission body coordinates with first transmission body and is rotated with the rotation of the first transmission body;
Wherein, first transmission body is configured as with the rotation axis:In the case where not applying the driving force, described One transmission body responds the rotation of second transmission body and along the axial movement of the rotation axis.
2. transmission mechanism as described in claim 1, which is characterized in that
First transmission body has worm screw;
Second transmission body has the worm gear for coordinating with the worm screw.
3. transmission mechanism as described in claim 1, which is characterized in that
First transmission body be socketed on the rotation axis enable first transmission body with the rotation of the rotation axis and Rotate and can be along the axial movement of the rotation axis.
4. transmission mechanism as described in claim 1, which is characterized in that
It is provided in at least one end of first transmission body in itself axial both ends for making first transmission body edge Restore after the axial movement of the rotation axis to the return unit of setting position.
5. transmission mechanism as claimed in claim 4, which is characterized in that
The return unit is elastic component.
6. transmission mechanism as claimed in claim 5, which is characterized in that
One end position of the elastic component is fixed, and the other end is abutted or connect with first transmission body.
7. the transmission mechanism as described in any one of claim 1-6, which is characterized in that further include:
Output gear coordinates with second transmission body and is rotated with the rotation of the second transmission body;
Piston impeller coordinates with the output gear and is moved along its length to push away with the rotation of the output gear Piston.
8. a kind of transmission mechanism of drug delivery device, including:
Rotation axis, for being rotated under the action of driving force;
First transmission body coordinates with the rotation axis and is rotated with the rotation of the rotation axis;
It is driven clamp mechanism, is coordinated with first transmission body, and with the output rotated with the rotation of first transmission body Gear;
Piston impeller coordinates with the output gear and is moved along its length to push away with the rotation of the output gear Piston;
Wherein, first transmission body can respond the output gear and the piston impeller from non-engagement state to engaging The variation of state and along the axial movement of the rotation axis.
9. transmission mechanism as claimed in claim 8, which is characterized in that
First transmission body has worm screw;
The transmission clamp mechanism has the worm gear coordinated with the worm screw.
10. a kind of drug delivery device, which is characterized in that including:
Drive system, for providing driving force;
Transmission system, for transmitting the driving force under the driving of the drive system;
Liquid reservoir is used for fluid storage;
Piston is located in the liquid reservoir, is used under the action of the driving force that the transmission system is transmitted, by the storage Fluid discharge in liquid device;
Wherein, the transmission system includes transmission mechanism as claimed in any one of claims 1-9 wherein.
CN201810129822.8A 2018-02-08 2018-02-08 Drug delivery device and its transmission mechanism Pending CN108421133A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810129822.8A CN108421133A (en) 2018-02-08 2018-02-08 Drug delivery device and its transmission mechanism

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810129822.8A CN108421133A (en) 2018-02-08 2018-02-08 Drug delivery device and its transmission mechanism

Publications (1)

Publication Number Publication Date
CN108421133A true CN108421133A (en) 2018-08-21

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Country Status (1)

Country Link
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108939203A (en) * 2018-08-23 2018-12-07 苏州新生命医疗科技有限公司 A kind of driving structure and high-precision drug infusion system of drug infusion system
CN109172934A (en) * 2018-08-23 2019-01-11 苏州新生命医疗科技有限公司 A kind of driving structure and drug infusion system of compact drug infusion system
CN110694146A (en) * 2019-10-25 2020-01-17 刘苏衡 Needleless injector

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006121921A2 (en) * 2005-05-06 2006-11-16 Medtronic Minimed, Inc. Infusion device and method with disposable portion
US20080097328A1 (en) * 2006-08-23 2008-04-24 Medtronic Minimed, Inc. Systems and methods allowing for reservoir filling and infusion medium delivery
US20080319394A1 (en) * 2007-06-11 2008-12-25 Medingo, Ltd. Portable infusion device with reduced level of operational noise
US20120172804A1 (en) * 2009-03-31 2012-07-05 Sanofi-Aventis Deutschland Gmbh Medicament delivery devices
CN102762241B (en) * 2009-12-30 2014-04-02 美敦力迷你迈德公司 Engagement and sensing systems and methods
CN209075720U (en) * 2018-02-08 2019-07-09 美敦力公司 Drug delivery device and its transmission mechanism

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006121921A2 (en) * 2005-05-06 2006-11-16 Medtronic Minimed, Inc. Infusion device and method with disposable portion
US20080097328A1 (en) * 2006-08-23 2008-04-24 Medtronic Minimed, Inc. Systems and methods allowing for reservoir filling and infusion medium delivery
US20080319394A1 (en) * 2007-06-11 2008-12-25 Medingo, Ltd. Portable infusion device with reduced level of operational noise
US20120172804A1 (en) * 2009-03-31 2012-07-05 Sanofi-Aventis Deutschland Gmbh Medicament delivery devices
CN102762241B (en) * 2009-12-30 2014-04-02 美敦力迷你迈德公司 Engagement and sensing systems and methods
CN209075720U (en) * 2018-02-08 2019-07-09 美敦力公司 Drug delivery device and its transmission mechanism

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108939203A (en) * 2018-08-23 2018-12-07 苏州新生命医疗科技有限公司 A kind of driving structure and high-precision drug infusion system of drug infusion system
CN109172934A (en) * 2018-08-23 2019-01-11 苏州新生命医疗科技有限公司 A kind of driving structure and drug infusion system of compact drug infusion system
CN110694146A (en) * 2019-10-25 2020-01-17 刘苏衡 Needleless injector

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Application publication date: 20180821