CN108421003A - A kind of antibacterial ointment and preparation method thereof for treating flat wart - Google Patents

A kind of antibacterial ointment and preparation method thereof for treating flat wart Download PDF

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CN108421003A
CN108421003A CN201810535985.6A CN201810535985A CN108421003A CN 108421003 A CN108421003 A CN 108421003A CN 201810535985 A CN201810535985 A CN 201810535985A CN 108421003 A CN108421003 A CN 108421003A
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flat wart
oil
antibacterial ointment
oyster
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郑和国
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Wuhan Runhe Biological Medical Co Ltd
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Wuhan Runhe Biological Medical Co Ltd
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Abstract

The present invention relates to a kind of antibacterial ointment and preparation method thereof for treating flat wart, belong to treatment flat wart technical field of pharmaceuticals, the parts by weight of each component are 3 ~ 7 parts of scouring rush, 2 ~ 5 parts of isatis root, 1 ~ 3 part of safflower, 2 ~ 5 parts of corter pseudolaricis, 2 ~ 5 parts of rhizoma cyperi, 1 ~ 4 part of crow courage, 1 ~ 4 part in one's early teens, 1 ~ 4 part of curcuma zedoary, 2 ~ 5 parts of Asian puccoon, 2 ~ 5 parts of oyster, 20 ~ 40 parts of castor oil, 2 ~ 5 parts of acetic acid chlorhexidine, 1 ~ 2 part of lauryl sodium sulfate, 2 ~ 5 parts of vitamin E oil, 1 ~ 3 part of glycerin monostearate；The antibacterial ointment is clearing heat and detoxicating, promoting blood circulation and removing blood stasis, softening and resolving hard mass, has preferable therapeutic effect for flat wart, and product contains traditional Chinese medicine ingredients, is free from side effects, is not easy repeatedly, curative effect is satisfactory.

Description

A kind of antibacterial ointment and preparation method thereof for treating flat wart
Technical field
The present invention relates to a kind of ointment and preparation method thereof, and in particular to a kind of antibacterial ointment and its system for treating flat wart Preparation Method belongs to treatment flat wart technical field of pharmaceuticals.
Background technology
Flat wart is a kind of common viral neoformation, and main hair is in teenager's face, the back of the hand and forearm, also known as youth Flat wart.Motherland's medicine is belonged to wart class, and someone is known as verruca plana in recent years, is caused by a kind of human papilloma virus, it It is to be infected by being in direct contact, also has and think through pollutant such as needle, brush etc. and indirect infection.Flat wart is in skin disease Common disease and frequently-occurring disease are not cured year in year out due to its recurrent exerbation, are brought great pain to patients.Chinese medicine thinks：This disease mostly by Skin interspaces of skin and muscles being loose, in wind-heat cult poison intrusive body, or liver void blood is dry in vivo, and muscle gas is not flourish, derangement of Qi and blood, and heat toxin outgoing smoulders skin Skin forms.Clinical manifestation is mainly in teenager, is apt to occur in face, the back of the hand, forearm etc.；Protuberance is put down for the grain of rice to big win of soya bean Papule, surface is smooth, and matter is hard, light brown or normal skin tone, and round, ellipse or polygonal, number is more, most intensive, more No conscious sympton, occasionally have it is micro- itch, the course of disease is slow, when or die away suddenly, it is also sustainable not to be cured for many years.
At present no matter at home, it is external very low to the cure rate of flat wart, only 25% or so, Mean treatment duration needs 3 A month or so, wart basal part often occurred inflammatory reaction before subsiding, and scratch exacerbation, but can recur, and only a few patient, which also has, occurs canceration Possibility.Medical field can not directly kill flat wart virus at present, so the method for the treatment of flat wart is all exempted from using raising human body Flat wart is suppressed and eliminated to epidemic disease function；It is treated using Loratadine, curative effect is not satisfactory enough, and corticosteroid swashs Extract for treating has certain side effect again, therefore the present invention proposes a kind of antibacterial ointment for treating flat wart, easy to use, and due to adopting It with traditional Chinese medicine ingredients, is free from side effects, uneasy to recur, curative effect is satisfactory.
Invention content
The present invention is and to propose a kind of antibacterial ointment for treating flat wart to solve the problems, such as the treatment of current flat wart. The antibacterial ointment can effectively treat flat wart, be free from side effects, uneasy to recur, be used multiple times, use is very convenient.
To achieve the above object, the present invention adopts the following technical scheme that：
A kind of antibacterial ointment for treating flat wart, which is characterized in that the parts by weight of each component are：
3 ~ 7 parts of scouring rush, 2 ~ 5 parts of isatis root, 1 ~ 3 part of safflower, 2 ~ 5 parts of corter pseudolaricis, 2 ~ 5 parts of rhizoma cyperi, 1 ~ 4 part of crow courage, in one's early teens 1 ~ 4 Part, 1 ~ 4 part of curcuma zedoary, 2 ~ 5 parts of Asian puccoon, 2 ~ 5 parts of oyster, 20 ~ 40 parts of castor oil, 2 ~ 5 parts of acetic acid chlorhexidine, lauryl sodium sulfate 1 ~ 2 part, 2 ~ 5 parts of vitamin E oil, 1 ~ 3 part of glycerin monostearate；
3 ~ 5 parts of scouring rush, 3 ~ 5 parts of isatis root, 2 ~ 3 parts of safflower, 2 ~ 5 parts of corter pseudolaricis, 2 ~ 5 parts of rhizoma cyperi, 1 ~ 4 part of crow courage, in one's early teens 1 ~ 4 Part, 1 ~ 4 part of curcuma zedoary, 2 ~ 5 parts of Asian puccoon, 2 ~ 5 parts of oyster, 20 ~ 40 parts of castor oil, 2 ~ 5 parts of acetic acid chlorhexidine, lauryl sodium sulfate 1 ~ 2 part, 2 ~ 5 parts of vitamin E oil, 1 ~ 3 part of glycerin monostearate；
4 ~ 7 parts of scouring rush, 2 ~ 4 parts of isatis root, 1 ~ 3 part of safflower, 2 ~ 4 parts of corter pseudolaricis, 2 ~ 4 parts of rhizoma cyperi, 1 ~ 4 part of crow courage, in one's early teens 1 ~ 4 Part, 1 ~ 4 part of curcuma zedoary, 2 ~ 5 parts of Asian puccoon, 2 ~ 5 parts of oyster, 20 ~ 40 parts of castor oil, 2 ~ 5 parts of acetic acid chlorhexidine, lauryl sodium sulfate 1 ~ 2 part, 2 ~ 5 parts of vitamin E oil, 1 ~ 3 part of glycerin monostearate.
A kind of antibacterial ointment preparation method for treating flat wart, which is characterized in that including following preparation process：
（1）It crushes：By scouring rush, isatis root, safflower, corter pseudolaricis, rhizoma cyperi, crow courage, in one's early teens, curcuma zedoary, Asian puccoon, the Chinese medicines such as oyster it is former Material is ground into fine powder with pulverizer；
（2）Decoction filtering：The purified water of 20 times of amounts of raw material gross weight is added in fine powder, decocts 2 ~ 3h, filtrate is collected in filtering； The water that 8 ~ 15 times of amounts of medicinal material weight are added in the dregs of a decoction again decocts 1 ~ 2h, and filtrate is collected in filtering, filtrate will merge twice；
（3）Concentration：The heating of above-mentioned filtrate is concentrated into the medicinal extract of semisolid；
（4）Drying and crushing：It by medicinal extract freeze-drying at solid, crushes, crosses 200 mesh sieve, obtain Chinese medicinal powder；
（5）Melt emulsification：It takes castor oil and acetic acid chlorhexidine to be heated in 70~80 DEG C of water-baths, melts, stir evenly, then Lauryl sodium sulfate, vitamin E oil and glycerin monostearate is added, heating fusing stirs evenly, obtains emulsion；
（6）Mixing：Chinese medicinal powder is added in above-mentioned emulsion, stirs evenly and cools down to get the antibacterial ointment.
The pharmacological property of the raw materials used in the present invention is as follows：
Scouring rush：Wind-dispelling heat-dissipating, expelling pathogenic factors from muscles and skin move back screen；
Radix Isatidis：It is clearing heat and detoxicating, cool blood relieving sore-throat；
Safflower：Invigorate blood circulation, stasis eliminatings analgesic；
Corter pseudolaricis：Dispelling wind and eliminating dampness, desinsection are antipruritic；
Rhizoma cyperi：Soothing liver-qi stagnation, regulating the flow of QI to ease the stomach, menstruction regulating and pain relieving；
Crow courage：It kills virus pest-resistant；
In one's early teens：Eliminating dampness promoting the circulation of qi, warming middle energizer to arrest vomiting；
Curcuma zedoary：Blood-breaking, Xiao Ji Zhi Tong；
Asian puccoon：Cool blood, promoting blood circulation, heat-clearing, removing toxic substances；
Castor oil：Bitter, cool in nature, purging intense heat, except steaming, detoxification sore treatment；
Oyster：Former animal contains glycogen, taurine, 10 kinds of essential amino acids, glutathione, vitamin A, B1.B2.D, inanimate matter Such as copper, zinc, manganese, barium, phosphorus and calcium, leucine contained therein, arginine, citrulling content are most abundant, are people so far The content that class is found one of marine species the highest；
Chlorhexidine acetate：Also it is Robenidine Roripa, chlorhexidine acetate, Chlorhexidine, double benzyl chloride chlorhexidine, for cation Surfactant, has a broad antifungal spectrum have killing effect to most Grain-positives and negative bacteria, also effective to Pseudomonas aeruginosa, use In operation remote holder, skin, planing surface and sterilization of instruments.
The invention has the advantages that and advantageous effect：
The present invention is based on modern Chinese medicines and doctor trained in Western medicine to the pathogenetic understanding of flat wart and principle of reatment, and selected traditional Chinese and western medicine drug is former Material, is formulated using unique formula；When treatment, takes this appropriate ointment to be applied to affected part, once a day or twice, be within one month One course for the treatment of；It takes effect within usual one month, can cure within 1~3 month, control difficulty in relapse after healing, have no toxic side effect.
Specific implementation mode
Product of the present invention is further described below in conjunction with the embodiment of the present invention, the description of embodiment is only for ease of understanding With with the application of the invention, rather than to the limitation protected of the present invention.Unless stated otherwise, preparation process under room temperature, normal pressure state into Row；Unless stated otherwise, the reagent that is used in the present invention, method and apparatus is the art conventional reagent, method and apparatus； Unless stated otherwise, the experimental condition used in the present invention is the art normal test conditions；Unless stated otherwise, this hair Bright middle agents useful for same is purchased in market.
Embodiment 1
A kind of antibacterial ointment for treating flat wart, the weight of each component are：
3 parts of scouring rush, 5 parts of isatis root, 3 parts of safflower, 5 parts of corter pseudolaricis, 5 parts of rhizoma cyperi, 4 parts of crow courage, 4 parts in one's early teens, 4 parts of curcuma zedoary is purple 5 parts of grass, 5 parts of oyster, 40 parts of castor oil, 5 parts of acetic acid chlorhexidine, 2 parts of lauryl sodium sulfate, 3 parts of vitamin E oil are single stearic 2 parts of acid glyceride；
A kind of antibacterial ointment preparation method for treating flat wart, including following preparation process：
（1）It crushes：By scouring rush, isatis root, safflower, corter pseudolaricis, rhizoma cyperi, crow courage, in one's early teens, curcuma zedoary, Asian puccoon, the Chinese medicines such as oyster it is former Material is ground into fine powder with pulverizer；
（2）Decoction filtering：The purified water of 20 times of amounts of raw material gross weight is added in fine powder, decocts 2 ~ 3h, filtrate is collected in filtering； The water that 8 ~ 15 times of amounts of medicinal material weight are added in the dregs of a decoction again decocts 1 ~ 2h, and filtrate is collected in filtering, filtrate will merge twice；
（3）Concentration：The heating of above-mentioned filtrate is concentrated into the medicinal extract of semisolid；
（4）Drying and crushing：It by medicinal extract freeze-drying at solid, crushes, crosses 200 mesh sieve, obtain Chinese medicinal powder；
（5）Melt emulsification：It takes castor oil and acetic acid chlorhexidine to be heated in 70~80 DEG C of water-baths, melts, stir evenly, then Lauryl sodium sulfate, vitamin E oil and glycerin monostearate is added, heating fusing stirs evenly, obtains emulsion；
（6）Mixing：Chinese medicinal powder is added in above-mentioned emulsion, stirs evenly and cools down to get the antibacterial ointment.
Embodiment 2
A kind of antibacterial ointment for treating flat wart, the weight of each component are：
5 parts of scouring rush, 3 parts of isatis root, 3 parts of safflower, 4 parts of corter pseudolaricis, 5 parts of rhizoma cyperi, 4 parts of crow courage, 4 parts in one's early teens, 3 parts of curcuma zedoary is purple 4 parts of grass, 4 parts of oyster, 35 parts of castor oil, 4 parts of acetic acid chlorhexidine, 2 parts of lauryl sodium sulfate, 3 parts of vitamin E oil are single stearic 2 parts of acid glyceride；
A kind of antibacterial ointment preparation method for treating flat wart, including following preparation process：
（1）It crushes：By scouring rush, isatis root, safflower, corter pseudolaricis, rhizoma cyperi, crow courage, in one's early teens, curcuma zedoary, Asian puccoon, the Chinese medicines such as oyster it is former Material is ground into fine powder with pulverizer；
（2）Decoction filtering：The purified water of 20 times of amounts of raw material gross weight is added in fine powder, decocts 2 ~ 3h, filtrate is collected in filtering； The water that 8 ~ 15 times of amounts of medicinal material weight are added in the dregs of a decoction again decocts 1 ~ 2h, and filtrate is collected in filtering, filtrate will merge twice；
（3）Concentration：The heating of above-mentioned filtrate is concentrated into the medicinal extract of semisolid；
（4）Drying and crushing：It by medicinal extract freeze-drying at solid, crushes, crosses 200 mesh sieve, obtain Chinese medicinal powder；
（5）Melt emulsification：It takes castor oil and acetic acid chlorhexidine to be heated in 70~80 DEG C of water-baths, melts, stir evenly, then Lauryl sodium sulfate, vitamin E oil and glycerin monostearate is added, heating fusing stirs evenly, obtains emulsion；
（6）Mixing：Chinese medicinal powder is added in above-mentioned emulsion, stirs evenly and cools down to get the antibacterial ointment.
Embodiment 3
A kind of antibacterial ointment for treating flat wart, the weight of each component are：
7 parts of scouring rush, 2 parts of isatis root, 2 parts of safflower, 2 parts of corter pseudolaricis, 2 parts of rhizoma cyperi, 2 parts of crow courage, 2 parts in one's early teens, 2 parts of curcuma zedoary is purple 3 parts of grass, 3 parts of oyster, 30 parts of castor oil, 3 parts of acetic acid chlorhexidine, 2 parts of lauryl sodium sulfate, 3 parts of vitamin E oil are single stearic 2 parts of acid glyceride；
A kind of antibacterial ointment preparation method for treating flat wart, including following preparation process：
（1）It crushes：By scouring rush, isatis root, safflower, corter pseudolaricis, rhizoma cyperi, crow courage, in one's early teens, curcuma zedoary, Asian puccoon, the Chinese medicines such as oyster it is former Material is ground into fine powder with pulverizer；
（2）Decoction filtering：The purified water of 20 times of amounts of raw material gross weight is added in fine powder, decocts 2 ~ 3h, filtrate is collected in filtering； The water that 8 ~ 15 times of amounts of medicinal material weight are added in the dregs of a decoction again decocts 1 ~ 2h, and filtrate is collected in filtering, filtrate will merge twice；
（3）Concentration：The heating of above-mentioned filtrate is concentrated into the medicinal extract of semisolid；
（4）Drying and crushing：It by medicinal extract freeze-drying at solid, crushes, crosses 200 mesh sieve, obtain Chinese medicinal powder；
（5）Melt emulsification：It takes castor oil and acetic acid chlorhexidine to be heated in 70~80 DEG C of water-baths, melts, stir evenly, then Lauryl sodium sulfate, vitamin E oil and glycerin monostearate is added, heating fusing stirs evenly, obtains emulsion；
（6）Mixing：Chinese medicinal powder is added in above-mentioned emulsion, stirs evenly and cools down to get the antibacterial ointment.
Clinical trial is reported：
One, situation of the antibacterial ointment of the present invention for clinical is as follows：In June, 2015 is to patient 223 during in May, 2017 Example, wherein man 130, female 93.
Two, diagnosis basis：According to《People's Republic of China's traditional Chinese medicine industry standard --- Chinese medical disease Standardization of diagnosis and curative effect （ZY/T001.1 ~ 94）》Regulation, with reference to " the judgement foundation of verruca plana ", in the grain of rice to the jowar grain flat papule of size at skin lesion, Surface is smooth, isolated to be dispersed in, and khaki or normal skin color or micro- itches；It is mainly in exposure portion, such as face, the back of the hand；Have certainly The characteristics of family's inoculation, it is seen that isomorphic effect；It sends out in teenager；Knit pathologic finding：Spinous layer of epidermis is plump, papillomatous hyperplasia and angle Change excessive, companion's parakeratosis.Spinous layer top and stratum granulosum have Empity veside cell, nuclear hyperchromatism, basophilla.
Three, efficacy evaluation：According to《People's Republic of China's traditional Chinese medicine industry standard --- Chinese medical disease Standardization of diagnosis and curative effect （ZY/T001.1 ~ 94）》Regulation cure with reference to " the effect of verruca plana evaluates "：Skin lesion is subsided, and nothing newly goes out fash；It improves：Fash It flattens earlier above, subsiding 30% or more or has individual new rash to occur；It is not cured：Fash is unchanged or recession is less than 30%.
Four, therapy：Patient take daily in right amount the ointment made of the present embodiment 2 be applied to affected part, once a day or Twice, a month as a course for the treatment of, and 2 course for the treatment of observation curative effects are used in conjunction.
Five, treatment results：Healing person 170 accounts for 76%, and improvement person 49 accounts for 22%, and more 4 do not account for 2%, and total effective rate reaches 98%, using other embodiments of the invention, there was no significant difference with 2 medication effect of the present embodiment is used.
Model case
1. Wu, man, 26 years old, Hubei people from Wuhan.Two the back of the hand papule of cause 3 years, went to see a doctor on January 22nd, 2016.Patient Because finding both hands dorsal stylet head after anger to the flat papule of sorghum size before 4 years, brown, surface is smooth, slightly higher for skin Surface, feel slightly itch, do not draw attention, after a few days skin lesion progressive aggravate, once repeatedly took antiviral drugs, take orally in Medicine treatment is showed no improvement.Found that papule increases, and expands, goes to see a doctor before January.Hospital checks display：36.3 DEG C of body temperature, just Normal face.The no positive sign of cardiopulmonary abdomen, the flat papule of both hands dorsal stylet head to sorghum size, brown, surface is smooth, slightly higher than In skin surface, diagnosis is flat wart.2 ointment of the embodiment of the present invention is used later, and fash all subsides after March, clinical Recovery from illness, follow-up are not recurred so far.
2. Zhao, women, 32 years old, Hubei people from Wuhan.Double upper limb papules 2 years were gone to see a doctor on April 23rd, 2016. There is flat papule of the both hands dorsal stylet head to sorghum size without obvious cause in patient's two years ago, and surface is smooth, slightly higher for skin table Feel and slightly itch, do not draw attention that skin lesion progressive aggravates after a few days, and once multiple antiviral therapy was showed no improvement in face.1 Find that double forearms have similar papule to occur before month.Above-mentioned symptom aggravates medical again.Hospital checks display：37.6 DEG C of body temperature, just The papule of normal face, the no positive sign of cardiopulmonary abdomen, the filbert sorghum in double upper limb mounds or bigger, rounded, partial fusion, slight scabies Itch, diagnosis is flat wart.1 ointment of the embodiment of the present invention is used later, and fash all subsides after March, clinical recovery, follow-up So far it does not recur.
3. it is sweet certain, male, 6 years old, Hubei people from Wuhan.Face, both hands back ofs the body papule March, hospital is arrived on May 2nd, 20116 It is medical.Patient suffered from cold before March after occur face, both hands dorsal stylet head to sorghum size flat papule, surface is smooth, it is slightly higher for Skin surface feels and slightly itches, do not draw attention that skin lesion progressive aggravates after a few days, without any treatment.It was found before 3 days Double forearms have similar papule occur above-mentioned symptom aggravate again it is medical.Hospital checks display：37.7 DEG C of body temperature, normal face, the heart The no positive sign of lung abdomen, blee, both hands carry on the back filbert syringe needle to the flat papule of sorghum size, oval, surface light It is sliding, it is slightly higher for skin surface, it feels and slightly itches, diagnosis is flat wart.Later use 3 ointment of the embodiment of the present invention, 2 Fash all subsides after month, and clinical recovery, follow-up is not recurred so far.
The above is only the application implementation mode of the present invention, it is noted that for the ordinary skill people of the art For member, without departing from the technical principles of the invention, several improvements and modifications can also be made, these improvements and modifications Also it should be regarded as protection scope of the present invention.

Claims (4)

1. a kind of antibacterial ointment for treating flat wart, which is characterized in that the parts by weight of each component are：
3 ~ 7 parts of scouring rush, 2 ~ 5 parts of isatis root, 1 ~ 3 part of safflower, 2 ~ 5 parts of corter pseudolaricis, 2 ~ 5 parts of rhizoma cyperi, 1 ~ 4 part of crow courage, in one's early teens 1 ~ 4 Part, 1 ~ 4 part of curcuma zedoary, 2 ~ 5 parts of Asian puccoon, 2 ~ 5 parts of oyster, 20 ~ 40 parts of castor oil, 2 ~ 5 parts of acetic acid chlorhexidine, lauryl sodium sulfate 1 ~ 2 part, 2 ~ 5 parts of vitamin E oil, 1 ~ 3 part of glycerin monostearate.
2. a kind of antibacterial ointment for treating flat wart, which is characterized in that the parts by weight of each component are：
3 ~ 5 parts of scouring rush, 3 ~ 5 parts of isatis root, 2 ~ 3 parts of safflower, 2 ~ 5 parts of corter pseudolaricis, 2 ~ 5 parts of rhizoma cyperi, 1 ~ 4 part of crow courage, in one's early teens 1 ~ 4 Part, 1 ~ 4 part of curcuma zedoary, 2 ~ 5 parts of Asian puccoon, 2 ~ 5 parts of oyster, 20 ~ 40 parts of castor oil, 2 ~ 5 parts of acetic acid chlorhexidine, lauryl sodium sulfate 1 ~ 2 part, 2 ~ 5 parts of vitamin E oil, 1 ~ 3 part of glycerin monostearate.
3. a kind of antibacterial ointment for treating flat wart, which is characterized in that the parts by weight of each component are：
4 ~ 7 parts of scouring rush, 2 ~ 4 parts of isatis root, 1 ~ 3 part of safflower, 2 ~ 4 parts of corter pseudolaricis, 2 ~ 4 parts of rhizoma cyperi, 1 ~ 4 part of crow courage, in one's early teens 1 ~ 4 Part, 1 ~ 4 part of curcuma zedoary, 2 ~ 5 parts of Asian puccoon, 2 ~ 5 parts of oyster, 20 ~ 40 parts of castor oil, 2 ~ 5 parts of acetic acid chlorhexidine, lauryl sodium sulfate 1 ~ 2 part, 2 ~ 5 parts of vitamin E oil, 1 ~ 3 part of glycerin monostearate.
4. a kind of antibacterial ointment preparation method for treating flat wart, which is characterized in that including following preparation process：
（1）It crushes：By scouring rush, isatis root, safflower, corter pseudolaricis, rhizoma cyperi, crow courage, in one's early teens, curcuma zedoary, Asian puccoon, the Chinese medicines such as oyster it is former Material is ground into fine powder with pulverizer；
（2）Decoction filtering：The purified water of 20 times of amounts of raw material gross weight is added in fine powder, decocts 2 ~ 3h, filtrate is collected in filtering； The water that 8 ~ 15 times of amounts of medicinal material weight are added in the dregs of a decoction again decocts 1 ~ 2h, and filtrate is collected in filtering, filtrate will merge twice；
（3）Concentration：The heating of above-mentioned filtrate is concentrated into the medicinal extract of semisolid；
（4）Drying and crushing：It by medicinal extract freeze-drying at solid, crushes, crosses 200 mesh sieve, obtain Chinese medicinal powder；
（5）Melt emulsification：It takes castor oil and acetic acid chlorhexidine to be heated in 70~80 DEG C of water-baths, melts, stir evenly, then Lauryl sodium sulfate, vitamin E oil and glycerin monostearate is added, heating fusing stirs evenly, obtains emulsion；
（6）Mixing：Chinese medicinal powder is added in above-mentioned emulsion, stirs evenly and cools down to get the antibacterial ointment.
CN201810535985.6A 2018-05-30 2018-05-30 A kind of antibacterial ointment and preparation method thereof for treating flat wart Withdrawn CN108421003A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110251553A (en) * 2019-07-31 2019-09-20 刘银生 A kind of traditional Chinese medicinal ointment and preparation method thereof for treating thorn monkey

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101461938A (en) * 2008-12-31 2009-06-24 泰安诺和诺泰生物制药有限公司 Preparation for treating flat wart and preparation method thereof
CN102716421A (en) * 2012-06-21 2012-10-10 中国人民解放军第三军医大学第一附属医院 Chinese medicine oral liquid for treating flat wart and preparation method of Chinese medicine oral liquid
CN105477446A (en) * 2015-12-17 2016-04-13 郭伟新 Traditional Chinese medicinal composition for treating verruca plana
CN105770593A (en) * 2016-03-23 2016-07-20 李王贻 Chinese-western integrated medicine for treating verruca vulgaris

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101461938A (en) * 2008-12-31 2009-06-24 泰安诺和诺泰生物制药有限公司 Preparation for treating flat wart and preparation method thereof
CN102716421A (en) * 2012-06-21 2012-10-10 中国人民解放军第三军医大学第一附属医院 Chinese medicine oral liquid for treating flat wart and preparation method of Chinese medicine oral liquid
CN105477446A (en) * 2015-12-17 2016-04-13 郭伟新 Traditional Chinese medicinal composition for treating verruca plana
CN105770593A (en) * 2016-03-23 2016-07-20 李王贻 Chinese-western integrated medicine for treating verruca vulgaris

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
王焕爱,等: "木贼汤治疗扁平疣60例", 《中医外治杂志》 *
郭永瑞: "中药治疗扁平疣48例疗效观察", 《菏泽医学专科学校学报》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110251553A (en) * 2019-07-31 2019-09-20 刘银生 A kind of traditional Chinese medicinal ointment and preparation method thereof for treating thorn monkey

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Application publication date: 20180821