CN108378271A - A kind of nutraceutical and preparation method thereof and application - Google Patents
A kind of nutraceutical and preparation method thereof and application Download PDFInfo
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- CN108378271A CN108378271A CN201810205494.5A CN201810205494A CN108378271A CN 108378271 A CN108378271 A CN 108378271A CN 201810205494 A CN201810205494 A CN 201810205494A CN 108378271 A CN108378271 A CN 108378271A
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- 239000002417 nutraceutical Substances 0.000 title claims abstract description 56
- 235000021436 nutraceutical agent Nutrition 0.000 title claims abstract description 56
- 238000002360 preparation method Methods 0.000 title abstract description 8
- 238000000855 fermentation Methods 0.000 claims abstract description 107
- 230000004151 fermentation Effects 0.000 claims abstract description 107
- 239000000843 powder Substances 0.000 claims abstract description 93
- 235000012149 noodles Nutrition 0.000 claims abstract description 64
- 235000007164 Oryza sativa Nutrition 0.000 claims abstract description 62
- 235000009566 rice Nutrition 0.000 claims abstract description 62
- 241000894006 Bacteria Species 0.000 claims abstract description 61
- 241000235342 Saccharomycetes Species 0.000 claims abstract description 60
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 49
- 240000005373 Panax quinquefolius Species 0.000 claims abstract description 48
- 239000000463 material Substances 0.000 claims abstract description 43
- 235000007215 black sesame Nutrition 0.000 claims abstract description 37
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 34
- 235000008434 ginseng Nutrition 0.000 claims abstract description 34
- 241000219784 Sophora Species 0.000 claims abstract description 27
- 208000002874 Acne Vulgaris Diseases 0.000 claims abstract description 25
- 206010000496 acne Diseases 0.000 claims abstract description 25
- 235000013305 food Nutrition 0.000 claims abstract description 20
- 239000002994 raw material Substances 0.000 claims abstract description 16
- 238000001035 drying Methods 0.000 claims abstract description 9
- 230000001954 sterilising effect Effects 0.000 claims abstract description 8
- 230000036541 health Effects 0.000 claims abstract description 6
- 235000016709 nutrition Nutrition 0.000 claims abstract description 6
- 241000209094 Oryza Species 0.000 claims description 61
- 235000013312 flour Nutrition 0.000 claims description 25
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 23
- 238000002156 mixing Methods 0.000 claims description 17
- 239000002002 slurry Substances 0.000 claims description 13
- 239000008223 sterile water Substances 0.000 claims description 13
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims description 10
- 210000000582 semen Anatomy 0.000 claims description 10
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 9
- 239000007788 liquid Substances 0.000 claims description 9
- 238000004519 manufacturing process Methods 0.000 claims description 9
- 235000021329 brown rice Nutrition 0.000 claims description 5
- 235000013402 health food Nutrition 0.000 claims description 4
- 230000035764 nutrition Effects 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 20
- 230000003115 biocidal effect Effects 0.000 abstract description 7
- 230000008030 elimination Effects 0.000 abstract description 3
- 238000003379 elimination reaction Methods 0.000 abstract description 3
- 241000208340 Araliaceae Species 0.000 abstract 1
- 240000007594 Oryza sativa Species 0.000 abstract 1
- 239000000243 solution Substances 0.000 description 48
- 239000000047 product Substances 0.000 description 7
- 230000004048 modification Effects 0.000 description 5
- 238000012986 modification Methods 0.000 description 5
- 238000011084 recovery Methods 0.000 description 5
- 108090000765 processed proteins & peptides Proteins 0.000 description 4
- 210000002784 stomach Anatomy 0.000 description 4
- 230000000052 comparative effect Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 239000000706 filtrate Substances 0.000 description 3
- 230000031700 light absorption Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 241001494479 Pecora Species 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 2
- OUUQCZGPVNCOIJ-UHFFFAOYSA-M Superoxide Chemical compound [O-][O] OUUQCZGPVNCOIJ-UHFFFAOYSA-M 0.000 description 2
- 238000002835 absorbance Methods 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 235000015895 biscuits Nutrition 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000007853 buffer solution Substances 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 230000001815 facial effect Effects 0.000 description 2
- 238000011049 filling Methods 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 230000002000 scavenging effect Effects 0.000 description 2
- 150000003384 small molecules Chemical class 0.000 description 2
- 235000019698 starch Nutrition 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- 238000010025 steaming Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000004577 thatch Substances 0.000 description 2
- QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 description 1
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 1
- 241000282693 Cercopithecidae Species 0.000 description 1
- 240000000588 Hericium erinaceus Species 0.000 description 1
- 235000007328 Hericium erinaceus Nutrition 0.000 description 1
- 206010033733 Papule Diseases 0.000 description 1
- 244000046101 Sophora japonica Species 0.000 description 1
- 235000010586 Sophora japonica Nutrition 0.000 description 1
- 208000000260 Warts Diseases 0.000 description 1
- 244000126002 Ziziphus vulgaris Species 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000009246 food effect Effects 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229940127249 oral antibiotic Drugs 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 235000020265 peanut milk Nutrition 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 150000003232 pyrogallols Chemical class 0.000 description 1
- 235000020095 red wine Nutrition 0.000 description 1
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- 231100000444 skin lesion Toxicity 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof
- A23L7/10—Cereal-derived products
- A23L7/104—Fermentation of farinaceous cereal or cereal material; Addition of enzymes or microorganisms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L25/00—Food consisting mainly of nutmeat or seeds; Preparation or treatment thereof
- A23L25/30—Mashed or comminuted products, e.g. pulp, pastes, meal, powders; Products made therefrom, e.g. blocks, flakes, snacks; Liquid or semi-liquid products
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L25/00—Food consisting mainly of nutmeat or seeds; Preparation or treatment thereof
- A23L25/40—Fermented products; Products treated with microorganisms or enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/065—Microorganisms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
- A23L5/10—General methods of cooking foods, e.g. by roasting or frying
- A23L5/13—General methods of cooking foods, e.g. by roasting or frying using water or steam
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Polymers & Plastics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Noodles (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to technical field of nutritional food, and in particular to a kind of nutraceutical and preparation method thereof and application.The nutraceutical is made of the raw material components of following parts by weight：50 100 parts of fermentation rice-flour noodles, 20 50 parts of black sesame powder, 15 parts of ginseng powder, 5 10 parts of sophora flower, 0.3 0.5 parts of saccharomycete bacterium solution A；Rice material is cleaned, dries rear grinds, obtained after saccharomycete bacterium solution B fermentation, sterilizing, drying by the fermentation rice-flour noodles, and the dosage of wherein saccharomycete bacterium solution B is the 35 ‰ of fermentation rice-flour noodles total weight parts.The present invention produces the nutraceutical with elimination whelk and acne, and raw material is free of antibiotic, not will produce antibiotic resistance problem using the low American Ginseng of common natural materials and side effect, health products can be used as to be used for a long time.
Description
Technical field
The invention belongs to technical field of nutritional food, and in particular to a kind of nutraceutical and preparation method thereof and application.
Background technology
With the continuous improvement of living standards, requirement of the people to food function is not only limited to full abdomen, more to pay close attention to
Point is nutrition and health.In the prior art, there are diversified health products, such as Hericium erinaceus biscuit, great thatch medicinal liquor etc., monkeys
Head mushroom biscuit has the function of that stomach invigorating nourishing the stomach, great thatch medicinal liquor can be with wind-damp dispelling, raising immunity etc., and different health products have not
Same healthcare function.
Whelk, acne etc. are a kind of chronic inflammatory skins of pilosebaceous unit, are mainly apt to occur in teenager,
Clinical manifestation is the pleomorphism skin lesions such as acne, papule, warts, tubercle, larger to teen-age psychology and social influence.Study table
Bright, the generation of whelk is related with hypersteatosis, after adolescing, since hormone in vivo level increases rapidly, so
Easily growth whelk, acne etc..The therapeutic modality of oral antibiotic, this treatment are used to whelk and acne in the prior art
Mode is although quick-acting, but the problem of easy to produce antibiotic resistance, is unfavorable for being used for a long time.Therefore it needs to develop a kind of pair
Act on the low nutraceutical with treatment whelk, acne.
Invention content
In order to solve the above technical problem, the present invention provides a kind of nutraceutical and preparation method thereof and application, exploitation
A kind of side effect is low and has effects that treat the nutraceutical of whelk, acne, solves and uses antibiotic in the prior art
Body caused by treatment whelk and acne leads to the problem of antibiotic resistance.
The first purpose of the invention is to provide a kind of nutraceutical, are made of the raw material components of following parts by weight：Fermentation
50-100 parts of rice flour, 20-50 parts of black sesame powder, 1-5 parts of ginseng powder, 5-10 parts of sophora flower, A0.3-0.5 parts of saccharomycete bacterium solution；
The fermentation rice-flour noodles are to clean rice material, dry rear grinds, after saccharomycete bacterium solution B fermentation, sterilizing, drying
It obtains, the dosage of wherein saccharomycete bacterium solution B is the 3-5 ‰ of fermentation rice-flour noodles total weight parts.
Preferably, in above-mentioned nutraceutical, 80 parts of fermentation rice-flour noodles, 35 parts of black sesame powder, 3 parts of ginseng powder, 8 parts of sophora flower,
A0.4 parts of saccharomycete bacterium solution.
Preferably, in above-mentioned nutraceutical, the rice material is brown rice or polished rice.
Preferably, in above-mentioned nutraceutical, the saccharomycete bacterium solution A and the saccharomycete bacterium solution B are expanded by saccharomyces cerevisiae
It cultivates greatly, the living bacteria count in the saccharomycete bacterium solution A and the saccharomycete bacterium solution B is >=107CFU/ml。
The present invention also provides a kind of production methods of above-mentioned nutraceutical, include the following steps：
S1 makes fermentation rice-flour noodles
Rice material is cleaned, dries rear grinds, obtains rice flour by S11；
Rice flour is mixed with yeast liquid B, adds the sterile water for being equivalent to rice flour quality 35%, wherein saccharomycete by S12
The dosage of bacterium solution B is the 3-5 ‰ of fermentation rice-flour noodles total weight parts, mixing, 20 ± 1 DEG C of fermentation 18-24h, finally dry to moisture≤
12%, obtain fermentation rice-flour noodles；
S2 makes black sesame powder, ginseng powder
Semen sesami nigrum is cleaned, fries rear grinds, obtains black sesame powder；
By American Ginseng grinds, ginseng powder is obtained；
S3 makes nutraceutical
S31 weighs each component by following parts by weight：50-100 parts of fermentation rice-flour noodles, 20-50 parts of black sesame powder, ginseng powder
1-5 parts, 5-10 parts of sophora flower, A0.3-0.5 parts of saccharomycete bacterium solution；
S32, the fermentation rice-flour noodles that S31 is weighed, black sesame powder, ginseng powder and the A mixing of saccharomycete bacterium solution, addition are equivalent to
The sterile water that 1.5 times of fermentation rice-flour noodles quality, is sufficiently mixed；Entering tank, tank mouth is sealed with two layers of gauze, after 15-20 DEG C of fermentation 4-6d,
It mixes thoroughly once, continues to be sealed with two layers of gauze, 15-25 DEG C of fermentation, stop fermentation after 5-10d, filter, collect filter residue；
The sophora flower that S31 is weighed is cleaned and drained away the water, colored slurry is ground into；
S33, it is the material bed of 5-10cm that the S32 filter residues collected, which are paved into thickness, steams 60-90min, is cooled to room temperature, adds
Enter the flower slurry that S32 is obtained, mix thoroughly, obtained material is dried to moisture≤5% through 40-50 DEG C, and regrinding completes battalion at powder
Support the making of food.
The present invention also provides a kind of above-mentioned nutraceutical as auxiliary treatment whelk, the application of acne health food.
The present invention also provides a kind of production methods of the nutraceutical to make for auxiliary treatment whelk, Cuo
Application in sore health food.
Compared with prior art, a kind of nutraceutical of the invention and preparation method thereof and application have below beneficial to effect
Fruit：
(1) rice is the staple food in people's diet, wherein containing abundant amino acid；Semen sesami nigrum can be with filling liver kidney, sheep blood, profit
The five internal organs；American Ginseng has the function of boosting qi and nourishing yin and clearing heat and promoting fluid；The effect of sophora flower is clearing liver-fire and anti-inflammatory.The present invention provides
A kind of nutraceutical above-mentioned several raw materials are used in combination for the first time, produce with the nutrition food for eliminating whelk and acne
Product, raw material are free of antibiotic, not will produce antibiotic resistance and ask using the low American Ginseng of common natural materials and side effect
Topic can be used as health products to be used for a long time.
The molecular weight of the nutraceutical small molecular peptide is in 1000Da hereinafter, be the small-molecule substance easily absorbed, reduction
Body stomach burden.It is found through application test, the nutraceutical is to the treated effect of whelk and acne up to 62% or more.
(2) influence of the raw material to food is not had to：Due to containing more starch in glutinous rice, viscosity is larger after steaming, is unfavorable for
The mixing starched with flower, thus it is preferable using brown rice and polished rice as rice material.
Influence of the different preparation methods to food curative effect：The product curative effect that different fermentation methods is made is different, sophora flower
Whether health-care effect that fermentation process influence whether entire food is participated in.
Specific implementation mode
With reference to specific example, the present invention is described in detail, but should not be construed as the limitation of the present invention.It is real below
Test method without specific conditions in example is carried out according to the conventional method of this field and condition.
In following embodiment and comparative examples, the saccharomycete bacterium solution A and the saccharomycete bacterium solution B by purchase wine of the same race
Brewer yeast is cultivated according to the standard expansion of food service industry, and the living bacteria count in saccharomycete bacterium solution A and saccharomycete bacterium solution B is equal
≥107CFU/ml；Culture medium when above-mentioned Spawn incubation is polished rice and water according to 1:2h is boiled after 20 mass ratio mixing, is taken advantage of
The Rice ＆ peanut milk that filtrate obtains is collected after heat filtering.
The present invention provides a kind of nutraceutical, are made of the raw material components of following parts by weight：50-100 parts of fermentation rice-flour noodles,
20-50 parts of black sesame powder, 1-5 parts of ginseng powder, 5-10 parts of sophora flower, A0.3-0.5 parts of saccharomycete bacterium solution；The fermentation rice-flour noodles are
Rice material is cleaned, rear grinds are dried, is obtained after saccharomycete bacterium solution B fermentation, sterilizing, drying, wherein saccharomycete bacterium solution B
Dosage be fermentation rice-flour noodles total weight parts 3-5 ‰.
Based on same inventive concept, the present invention also provides a kind of production method of above-mentioned nutraceutical, including it is following
Step：
S1 makes fermentation rice-flour noodles
Rice material is cleaned, dries rear grinds, obtains rice flour by S11；
S12 mixes rice flour with yeast liquid B, and the dosage of wherein saccharomycete bacterium solution B is the 3- of fermentation rice-flour noodles total weight parts
5 ‰, add the sterile water for being equivalent to rice flour quality 35%, mixing, 20 ± 1 DEG C of fermentation 18-24h, finally dry to moisture≤
12%, obtain fermentation rice-flour noodles；
S2 makes black sesame powder, ginseng powder
Semen sesami nigrum is cleaned, fries rear grinds, obtains black sesame powder；
By American Ginseng grinds, ginseng powder is obtained；
S3 makes nutraceutical
S31 weighs each component by following parts by weight：50-100 parts of fermentation rice-flour noodles, 20-50 parts of black sesame powder, ginseng powder
1-5 parts, 5-10 parts of sophora flower, 0.3-0.5 parts of saccharomycete bacterium solution A；
S32, the fermentation rice-flour noodles that S31 is weighed, black sesame powder, ginseng powder and the A mixing of saccharomycete bacterium solution, addition are equivalent to
The sterile water that 1.5 times of fermentation rice-flour noodles quality, is sufficiently mixed；Entering tank, tank mouth is sealed with two layers of gauze, after 15-20 DEG C of fermentation 4-6d,
It mixes thoroughly once, continues to be sealed with two layers of gauze, 15-25 DEG C of fermentation, stop fermentation after 5-10d, filter, collect filter residue；
The sophora flower that S31 is weighed is cleaned and drained away the water, colored slurry is ground into；
S33, it is the material bed of 5-10cm that the S32 filter residues collected, which are paved into thickness, steams 60-90min, is cooled to room temperature, adds
Enter the flower slurry that S32 is obtained, mix thoroughly, obtained material is dried to moisture≤5% through 40-50 DEG C, and regrinding completes battalion at powder
Support the making of food.
Specifically include following embodiment.
Embodiment 1
A kind of nutraceutical is made of the raw material components of following parts by weight：80 parts of fermentation rice-flour noodles, 35 parts of black sesame powder, west
3 parts of American ginseng powder, 8 parts of sophora flower, A0.4 parts of saccharomycete bacterium solution；The fermentation rice-flour noodles are to clean rice material, dry rear grinds, warp
It is obtained after saccharomycete bacterium solution B fermentation, sterilizing, drying, the dosage of wherein saccharomycete bacterium solution B is fermentation rice-flour noodles total weight parts
3‰。
The production method of above-mentioned nutraceutical, includes the following steps：
S1 makes fermentation rice-flour noodles
S11, rice material is cleaned, dry after wear into 200 mesh powder, obtain rice flour, the rice material is polished rice；
S12 mixes rice flour with yeast liquid B, and the dosage of wherein saccharomycete bacterium solution B is fermentation rice-flour noodles total weight parts
3 ‰, add the sterile water for being equivalent to rice flour quality 35%, mixing, 20 ± 1 DEG C of fermentation 20h, finally dry to moisture≤
12%, obtain fermentation rice-flour noodles；
S2 makes black sesame powder, ginseng powder
Semen sesami nigrum is cleaned, fry after wear into 200 mesh powder, obtain black sesame powder；
The Chinese medicinal material American Ginseng of purchase is worn into 200 mesh powder, obtains ginseng powder；
S3 makes nutraceutical
S31 weighs each component by following parts by weight：80 parts of fermentation rice-flour noodles, 35 parts of black sesame powder, 3 parts of ginseng powder, sophora flower
8 parts, 0.4 part of saccharomycete bacterium solution A；
S32, the fermentation rice-flour noodles that S31 is weighed, black sesame powder, ginseng powder and the A mixing of saccharomycete bacterium solution, addition are equivalent to
The sterile water that 1.5 times of fermentation rice-flour noodles quality, is sufficiently mixed；Enter tank, tank mouth is sealed with two layers of hospital gauze, 15-20 DEG C of fermentation 5d
Afterwards, it mixes thoroughly once, continues to be sealed with two layers of hospital gauze, 15-25 DEG C of fermentation, stop fermentation after 7d, filter, collect filter residue；
The sophora flower that S31 is weighed is cleaned and drained away the water, colored slurry is ground into；
S33, it is the material bed of 10cm that the S32 filter residues collected, which are paved into thickness, steams 90min, is cooled to room temperature, S32 is added
Obtained flower slurry, is mixed thoroughly, and obtained material is dried to moisture≤5% through 50 DEG C, and regrinding is completed at evengranular powder
The making of nutraceutical.
Embodiment 2
A kind of nutraceutical is made of the raw material components of following parts by weight：50 parts of fermentation rice-flour noodles, 50 parts of black sesame powder, west
5 parts of American ginseng powder, 10 parts of sophora flower, A0.3 parts of saccharomycete bacterium solution；The fermentation rice-flour noodles be rice material is cleaned, dry rear grinds,
It is obtained after saccharomycete bacterium solution B fermentation, sterilizing, drying, the dosage of wherein saccharomycete bacterium solution B is fermentation rice-flour noodles total weight parts
5‰。
The production method of above-mentioned nutraceutical, includes the following steps：
S1 makes fermentation rice-flour noodles
S11, rice material is cleaned, dry after wear into 200 mesh powder, obtain rice flour, the rice material is polished rice；
S12 mixes rice flour with yeast liquid B, and the dosage of wherein saccharomycete bacterium solution B is fermentation rice-flour noodles total weight parts
5 ‰, the sterile water for being equivalent to rice flour quality 35% is added, mixing, 20 ± 1 DEG C ferment for 24 hours, finally drying to moisture≤
12%, obtain fermentation rice-flour noodles；
S2 makes black sesame powder, ginseng powder
Semen sesami nigrum is cleaned, fry after wear into 200 mesh powder, obtain black sesame powder；
The Chinese medicinal material American Ginseng of purchase is worn into 200 mesh powder, obtains ginseng powder；
S3 makes nutraceutical
S31 weighs each component by following parts by weight：50 parts of fermentation rice-flour noodles, 50 parts of black sesame powder, 5 parts of ginseng powder, sophora flower
10 parts, 0.3 part of saccharomycete bacterium solution A；
S32, the fermentation rice-flour noodles that S31 is weighed, black sesame powder, ginseng powder and the A mixing of saccharomycete bacterium solution, addition are equivalent to
The sterile water that 1.5 times of fermentation rice-flour noodles quality, is sufficiently mixed；Enter tank, tank mouth is sealed with two layers of hospital gauze, 15-20 DEG C of fermentation 4d
Afterwards, it mixes thoroughly once, continues to be sealed with two layers of hospital gauze, 15-20 DEG C of fermentation, stop fermentation after 5d, filter, collect filter residue；
The sophora flower that S31 is weighed is cleaned and drained away the water, colored slurry is ground into；
S33, it is the material bed of 5cm that the S32 filter residues collected, which are paved into thickness, steams 60min, is cooled to room temperature, and S32 is added and obtains
The flower slurry arrived, is mixed thoroughly, and obtained material is dried to moisture≤5% through 40 DEG C, and regrinding completes battalion at evengranular powder
Support the making of food.
Embodiment 3
A kind of nutraceutical is made of the raw material components of following parts by weight：100 parts of fermentation rice-flour noodles, 20 parts of black sesame powder, west
1 part of American ginseng powder, 5 parts of sophora flower, 0.5 part of saccharomycete bacterium solution A；The fermentation rice-flour noodles be rice material is cleaned, dry rear grinds,
It is obtained after saccharomycete bacterium solution B fermentation, sterilizing, drying, the dosage of wherein saccharomycete bacterium solution B is fermentation rice-flour noodles total weight parts
4‰。
The production method of above-mentioned nutraceutical, includes the following steps：
S1 makes fermentation rice-flour noodles
S11, rice material is cleaned, dry after wear into 300 mesh powder, obtain rice flour, the rice material is brown rice；
S12 mixes rice flour with yeast liquid B, and the dosage of wherein saccharomycete bacterium solution B is fermentation rice-flour noodles total weight parts
4 ‰, add the sterile water for being equivalent to rice flour quality 35%, mixing, 20 ± 1 DEG C of fermentation 18h, finally dry to moisture≤
12%, obtain fermentation rice-flour noodles；
S2 makes black sesame powder, ginseng powder
Semen sesami nigrum is cleaned, fry after wear into 300 mesh powder, obtain black sesame powder；
The Chinese medicinal material American Ginseng of purchase is worn into 300 mesh powder, obtains ginseng powder；
S3 makes nutraceutical
S31 weighs each component by following parts by weight：100 parts of fermentation rice-flour noodles, 20 parts of black sesame powder, 1 part of ginseng powder, Chinese scholartree
Spend 5 parts, 0.5 part of saccharomycete bacterium solution A；
S32, the fermentation rice-flour noodles that S31 is weighed, black sesame powder, ginseng powder and the A mixing of saccharomycete bacterium solution, addition are equivalent to
The sterile water that 1.5 times of fermentation rice-flour noodles quality, is sufficiently mixed；Enter tank, tank mouth is sealed with two layers of hospital gauze, 15-20 DEG C of fermentation 6d
Afterwards, it mixes thoroughly once, continues to be sealed with two layers of hospital gauze, 20-25 DEG C of fermentation, stop fermentation after 10d, filter, collect filter residue；
The sophora flower that S31 is weighed is cleaned and drained away the water, colored slurry is ground into；
S33, it is the material bed of 7cm that the S32 filter residues collected, which are paved into thickness, steams 80min, is cooled to room temperature, and S32 is added and obtains
The flower slurry arrived, is mixed thoroughly, and obtained material is dried to moisture≤5% through 45 DEG C, and regrinding completes battalion at evengranular powder
Support the making of food.
Rice is the staple food in people's diet, wherein containing abundant amino acid；Semen sesami nigrum can be with filling liver kidney, sheep blood, profit five
It is dirty；American Ginseng has the function of boosting qi and nourishing yin and clearing heat and promoting fluid；The effect of sophora flower is clearing liver-fire and anti-inflammatory.It is provided by the invention
Above-mentioned several raw materials are used in combination for the first time for a kind of nutraceutical, produce with the nourishing and health food for eliminating whelk and acne
Product.Illustrate the effect of the present invention by taking embodiment 1-3 as an example below.
One, the molecular weight of nutraceutical small molecular peptide
The molecular weight of embodiment 1-3 small molecular peptides is in 1000Da hereinafter, explanation is after saccharomycetes to make fermentation, in raw material
Macromolecular substances are changed into the small-molecule substance easily absorbed, reduce body stomach and absorb burden.
Two, superoxide anion (O2-) Scavenging activity measurement
Using riboflavin-light-nitroblue tetrazolium system of determination.By 4.5mL Tris-HCl buffer solutions (25 DEG C, pH8.2,
25 DEG C of water-bath 20min 50mmol/L) are put into, 1mg embodiments 1 are added spends fine peptide solid beverage, adds 0.4mL pyrogallols
Solution (25mmol/L), 25 DEG C of water-bath 5min of mixing are added 1mL HCl solutions (8mmol/L) and survey absorbance A at 325nm, steam
Distilled water does blank, surveys absorbance A0, it is As that 4.5mLTris-HCl buffer solutions, which are added 1mL sample liquids and measure control light absorption value,.
Clearance rate (%)=[A- (AS-A0)]/A × 100%
Wherein A is sample liquid light absorption value, ASTo compare light absorption value, A0For blank absorbency.
After measured, nutraceutical made from embodiment 1,2,3 has certain Scavenging activity to superoxide anion, removes energy
Power is respectively 51.1%, 45.6% and 44.2%.
Three, application example
1, subjects
Choose whelk of the age at 13-18 Sui, patients with acne crowd 100, wherein 55 people of male, 45 people of women.
2, instructions of taking
Above-mentioned patient takes nutraceutical made from embodiment 1, is taken for early, middle and late 3 times per bu, takes 20g every time,
It is drunk after being reconstituted with warm water；30 are even served, result is observed and recorded.Wherein, whelk and acne area elimination factor >=50% are
Effectively；It completely disappears as recovery from illness.
3, test result
The health-care effect of nutraceutical provided by the invention：After 15 days, male suffers from the continuous nutraceutical for taking embodiment 1
Effective treatment number of whelk and acne is 15 people in person, and effective treatment number of whelk and acne is 16 in female patient
People；The continuous nutraceutical for taking embodiment 1 is after 21 days, and effective treatment number of whelk and acne is 20 in male patient
People, recovery from illness number are 2 people, and effective treatment number of whelk and acne is 21 people in female patient, and recovery from illness number is 3 people.Even
The continuous nutraceutical for taking embodiment 1 is after 30 days, and effective treatment number of whelk and acne is 36 people, recovery from illness in male patient
Number is 15 people, and treated effect 65.5%, effective treatment number of whelk and acne is 28 people in female patient, is fully recovered
Number is 15 people；Treated effect is 62.2%.
Four, influence of the different material to food
We prepare fermentation rice-flour noodles using glutinous rice as rice material, and nutraceutical is prepared according to the method for embodiment 1, due to
Containing more starch in glutinous rice, viscosity is larger after steaming, is unfavorable for the mixing with flower slurry, therefore using brown rice and polished rice as rice material
Preferably.
Five, influence of the different preparation methods to food curative effect
We have found that different raw materials is suitable for different processing modes, while we have found that rice flour, Semen sesami nigrum, the West
The nutraceutical that ginseng, sophora flower and saccharomycete are made jointly has effects that treat whelk and acne, but is different fermentation side
The product curative effect that formula is made is different.A comparative example is set forth below：
A kind of nutraceutical, it is made of the raw material components of following parts by weight：80 parts of fermentation rice-flour noodles, 35 parts of black sesame powder, west
3 parts of American ginseng powder, 8 parts of sophora flower, 0.4 part of saccharomycete bacterium solution A；The fermentation rice-flour noodles be rice material is cleaned, dry rear grinds,
It is obtained after saccharomycete bacterium solution B fermentation, sterilizing, drying, the dosage of wherein saccharomycete bacterium solution B is fermentation rice-flour noodles total weight parts
3‰。
The production method of above-mentioned jujube glutinous rice red wine, includes the following steps：
S1 makes fermentation rice-flour noodles
S11, rice material is cleaned, dry after wear into 200 mesh powder, obtain rice flour；
S12 mixes rice flour with yeast liquid B, and the dosage of wherein saccharomycete bacterium solution B is fermentation rice-flour noodles total weight parts
3 ‰, add the sterile water for being equivalent to rice flour quality 35%, mixing, 20 ± 1 DEG C of fermentation 20h, finally dry to moisture≤
12%, obtain fermentation rice-flour noodles；
S2 makes black sesame powder, ginseng powder
Semen sesami nigrum is cleaned, fry after wear into 200 mesh powder, obtain black sesame powder；
The Chinese medicinal material American Ginseng of purchase is worn into 200 mesh powder, obtains ginseng powder；
S3 makes nutraceutical
S31 weighs each component by following parts by weight：80 parts of fermentation rice-flour noodles, 35 parts of black sesame powder, 3 parts of ginseng powder, sophora flower
8 parts, 0.4 part of saccharomycete bacterium solution A；
The each component that S31 is weighed is sufficiently mixed by S32；Enter tank, tank mouth is sealed with two layers of hospital gauze, 15-20 DEG C of fermentation
It after 5d, mixes thoroughly once, continues to be sealed with two layers of gauze, 15-25 DEG C of fermentation, stop fermentation after 7d, filter, collect filter residue；It obtains
Filter residue to be paved into thickness be the material bed of 10cm, steam 90min, be then dried to moisture≤5% through 50 DEG C, regrind into particle
Uniform powder completes the making of nutraceutical.
Application test is carried out with the nutraceutical that above-mentioned comparative example is made, instructions of taking is：Early, middle and late 3 clothes per bu
With taking 20g every time, drunk after being reconstituted with warm water；30 are even served, result is observed and recorded.Wherein whelk and acne elimination factor
>=50%, it is effective；It completely disappears as recovery from illness.The result shows that either male or women, the treated effect of food are
30% or so, illustrate whether sophora flower participates in the health-care effect that fermentation process influences whether entire food.
It should be noted that in the S32 of 1-3 of the embodiment of the present invention, filters the filter residue collected later and be used to prepare nutrition food
Product, for the filtrate of collection after flame filter press filters, the filtrate collected again can also be directly as facial cleaning solution, Huo Zhetian
Appropriate additive is added to prepare other facial cleaning solutions, it may have the effect of antibacterial is with whelk, acne is prevented.
It should be noted that involved in the present invention when numberical range, it is thus understood that two endpoints of each numberical range with
And any one numerical value can be selected between two endpoints, since the step method of use is identical as embodiment, go to live in the household of one's in-laws on getting married in order to prevent
It stating, the present invention describes preferred embodiment, although preferred embodiments of the present invention have been described, but technology people in the art
Member is once know basic creative concept, then additional changes and modifications may be made to these embodiments.So appended right
It is required that being intended to be construed to include preferred embodiment and fall into all change and modification of the scope of the invention.
Obviously, various changes and modifications can be made to the invention without departing from essence of the invention by those skilled in the art
God and range.In this way, if these modifications and changes of the present invention belongs to the range of the claims in the present invention and its equivalent technologies
Within, then the present invention is also intended to include these modifications and variations.
Claims (7)
1. a kind of nutraceutical, which is characterized in that be made of the raw material components of following parts by weight：It is 50-100 parts of fermentation rice-flour noodles, black
20-50 parts of black sesame powder, 1-5 parts of ginseng powder, 5-10 parts of sophora flower, A0.3-0.5 parts of saccharomycete bacterium solution；
The fermentation rice-flour noodles are to clean rice material, dry rear grinds, obtained after saccharomycete bacterium solution B fermentation, sterilizing, drying
, the dosage of wherein saccharomycete bacterium solution B is the 3-5 ‰ of fermentation rice-flour noodles total weight parts.
2. nutraceutical according to claim 1, which is characterized in that be made of the raw material components of following parts by weight：Fermentation
80 parts of rice flour, 35 parts of black sesame powder, 3 parts of ginseng powder, 8 parts of sophora flower, A0.4 parts of saccharomycete bacterium solution.
3. nutraceutical according to claim 1, which is characterized in that the rice material is brown rice or polished rice.
4. nutraceutical according to claim 1, which is characterized in that the saccharomycete bacterium solution A and saccharomycete bacterium solution B
By saccharomyces cerevisiae expansion cultivate, and the living bacteria count in the saccharomycete bacterium solution A and the saccharomycete bacterium solution B >=
107CFU/ml。
5. the production method of nutraceutical according to claim 1, which is characterized in that include the following steps：
S1 makes fermentation rice-flour noodles
Rice material is cleaned, dries rear grinds, obtains rice flour by S11；
S12 mixes rice flour with yeast liquid B, and the dosage of wherein saccharomycete bacterium solution B is the 3-5 ‰ of fermentation rice-flour noodles total weight parts,
The sterile water for being equivalent to rice flour quality 35%, mixing are added, 20 ± 1 DEG C of fermentation 18-24h are finally dried to moisture≤12%,
Obtain fermentation rice-flour noodles；
S2 makes black sesame powder, ginseng powder
Semen sesami nigrum is cleaned, fries rear grinds, obtains black sesame powder；
By American Ginseng grinds, ginseng powder is obtained；
S3 makes nutraceutical
S31 weighs each component by following parts by weight：50-100 parts of fermentation rice-flour noodles, 20-50 parts of black sesame powder, ginseng powder 1-5
Part, 5-10 parts of sophora flower, A0.3-0.5 parts of saccharomycete bacterium solution；
S32, the fermentation rice-flour noodles that S31 is weighed, black sesame powder, ginseng powder and the A mixing of saccharomycete bacterium solution, addition are equivalent to fermentation
The sterile water that 1.5 times of rice flour quality, is sufficiently mixed；Enter tank, tank mouth is sealed with two layers of gauze, after 15-20 DEG C of fermentation 4-6d, is mixed thoroughly
Once, continue to be sealed with two layers of gauze, 15-25 DEG C of fermentation, stop fermentation after 5-10d, filter residue is collected in filtering；
The sophora flower that S31 is weighed is cleaned and drained away the water, colored slurry is ground into；
S33, it is the material bed of 5-10cm that the S32 filter residues collected, which are paved into thickness, steams 60-90min, is cooled to room temperature, S32 is added
Obtained flower slurry, is mixed thoroughly, and obtained material is dried to moisture≤5% through 40-50 DEG C, and regrinding completes nutrition food at powder
The making of product.
6. nutraceutical according to claim 1 is as auxiliary treatment whelk, the application of acne health food.
7. the production method of nutraceutical according to claim 5 is making for auxiliary treatment whelk, acne health care
Application in food.
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