CN108355007A - A kind of Chinese medicine composition and preparation method thereof of complex treatment sheep disease - Google Patents

A kind of Chinese medicine composition and preparation method thereof of complex treatment sheep disease Download PDF

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CN108355007A
CN108355007A CN201810166283.5A CN201810166283A CN108355007A CN 108355007 A CN108355007 A CN 108355007A CN 201810166283 A CN201810166283 A CN 201810166283A CN 108355007 A CN108355007 A CN 108355007A
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chinese medicine
medicine composition
complex treatment
sheep
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黄波
黄建
黄玉祥
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Pu An County Construction Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • A61K36/575Magnolia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
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  • Alternative & Traditional Medicine (AREA)
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  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The present invention relates to Technology of Processing Chinese Herbal Medicines fields, more particularly to a kind of Chinese medicine composition and preparation method thereof of complex treatment sheep disease, medicament of the present invention formula composition is simple, and raw material are easy to get, inexpensively, and it is various to prepare dosage form, occupation mode is various, it is safe and non-toxic, the immunity of organisms of sheep can be increased, reduce sheep flu, parasitic infection, the incidence of depilation, therapeutic effect are notable;In addition, during entire sheep cultivates, its appetite of the sheep of cultivation is preferable, and the state of mind is good, digests and assimilates, is newly fast at metabolism, weight is higher than the 10 15% of traditional cultural method when sheep, which reaches, to be delivered for sale, and the quality of mutton also has improvement.

Description

A kind of Chinese medicine composition and preparation method thereof of complex treatment sheep disease
Technical field
The present invention relates to Technology of Processing Chinese Herbal Medicines fields, and in particular to a kind of Chinese medicine composition of complex treatment sheep disease and Preparation method.
Background technology
With China's rapid development of economy and people's living standards continue to improve, aquaculture has become manyly The important industry that side develops the economy, uplifts the people's living standard.Wherein, it is that development aquaculture wants emphasis to carry out mutton sheep production work One content of concern, the cultivation of current mutton sheep have been not limited solely to domestic, carry out mutton sheep raising in mountain area also and have and is non- The development prospect of Chang Keguan.Although the mutton sheep cultivation in mountain area has many advantages, since mountain area ground is rugged and rough, more mountains Mound, gully, or even there are some hazard regions.Traffic of mountain area is undeveloped, and information occlusion understands fresh information in the market Speed is slow, degree is shallow, the transport to sheep product as the problems such as alpine terrain and traffic be affected to some extent.If There can be drought and water shortage in the Northwest, there can be the influence of the extreme natural cause such as cold frost in the Northeast.So this A little factors restrict mountain area mutton sheep and cultivate to form scale, intensive industry.In addition, mountain area sheep raising temperature change is big, weather is multiple Miscellaneous changeable, these all can generate puzzlement to the sound development of mutton sheep.
Therefore, the disease easily sent out of mountain area cultivation sheep has the sheep flu, Sheep Alopecia, Yang Kou that the variation due to season brings Fever aphthous, environment are complicated, the parasitic disease that the germ that moist weather is grown causes.The disease faced is cultivated for mountain area sheep at present It mostly aims at prevention, causes treatment complicated since disease is a variety of, curative effect is slow, and effect is poor.
Invention content
The present invention in order to solve problem above, provides Chinese medicine composition and its preparation side of a kind of complex treatment sheep disease Method.
It is realized especially by following technical scheme:
A kind of Chinese medicine composition of complex treatment sheep disease, includes the raw material of following mass parts meter:35-80 parts of sargentodoxa cuneata, 20-57 parts of cynomorium songaricum, 20-50 parts of matrimony vine, 17-40 parts of hawthorn, 10-28 parts of cloves, 5-20 parts of Cortex Magnoliae Officinalis, 5-20 parts of Radix Glycyrrhizae.
Further, the Chinese medicine composition of the complex treatment sheep disease, includes the raw material of following mass parts meter:Sargentodoxa cuneata 67-74 parts, 35-42 parts of cynomorium songaricum, 30-36 parts of matrimony vine, 24-36 parts of hawthorn, 14-20 parts of cloves, 8-13 parts of Cortex Magnoliae Officinalis, Radix Glycyrrhizae 7-10 Part.
Further, the Chinese medicine composition of the complex treatment sheep disease, including following preparation process:
1) sargentodoxa cuneata, cynomorium songaricum crush, and are soaked in solution 1,50-60 DEG C of heating stirring 4-7h, are left to ferment 5-7 days, obtain Fermentation material 1, the clear water that 1 times of 1 mass of fermentation material is added decoct 4-5 h, and filtering obtains filtrate 1;
2) matrimony vine, cloves, Cortex Magnoliae Officinalis mixing, high-temperature heating are soaked in 20-30 min in hydrochloric acid solution, and low temperature bakes, powder It is broken, it is spare to obtain powder 1;
3) hawthorn, Radix Glycyrrhizae, filtrate 1, powder 1 mix, and the extracting solution 1 of 2-3 times of quality is added in 60-70 DEG C of stirring 3-5h, 30-40 DEG C of standing 3-5h, filtering take filtrate, obtain filtrate 2, filtrate 2 is prepared into dosage form.
Further, the solution 1 is rice wine, tomato, capsicum, sodium chloride, clear water according to mass ratio 5-8:2-3:1- 2:0.5-1.3:15-20 is mixed, ultrasonic extraction, and 4-7 DEG C of standing 3-6h, 80-90 DEG C is heated 20-30min and filtered to obtain the final product.
Further, the fermentation is fermented 3-4 days under the conditions of 23-28 DEG C, is added the milk powder of 3-5%, 30-37 DEG C Fermentation 2-3 days.
Further, the high-temperature heating is to handle 4-5min under 240-300 DEG C, 1.5-2.4MPa.
Further, the extracting solution 1 is pawpaw, clear water according to mass ratio 3-5:40-50 mixing ultrasonications are inoculated with 1- 1.3% bacillus subtilis, normal temperature fermentation 3-5 days and obtain, filtering and obtain.
Further, the Chinese medicine composition of the complex treatment sheep disease, therapeutic effect are not limited by dosage form;User Method includes for oral administration, external application.
Advantageous effect:Compared with prior art, the present invention having progress following prominent
1) reagent combination composition is simple, and raw material are easy to get, inexpensively, and preparation dosage form is various, and occupation mode is various, safe nothing Poison.
2) immunity of organisms of sheep can be increased, reduce sheep flu, parasitic infection, the incidence of depilation, therapeutic effect is shown It writes.
3) in addition, entire sheep cultivate during, its appetite of the sheep of cultivation is preferable, and the state of mind is good, digest and assimilate, newly at Metabolism is fast, and when sheep, which reaches, to be delivered for sale, weight is higher than the 10-15% of traditional cultural method, and the quality of mutton also has improvement, meat table It is now succulence, fresh and tender and surface dry, illustrate to improve muscle is waterpower, improves the succulence of meat, tenderness also obtains It improves.
Specific implementation mode
Specific embodiments of the present invention will be described in further detail below, but the invention is not limited in these realities Mode is applied, it is claimed to still fall within the claims in the present invention for any improvement or replacement on the present embodiment essence spirit Range.
Embodiment 1
A kind of Chinese medicine composition of complex treatment sheep disease, includes the raw material of following mass parts meter:Sargentodoxa cuneata 35g, cynomorium songaricum 20g, matrimony vine 20g, hawthorn 17g, cloves 10g, Cortex Magnoliae Officinalis 5g, Radix Glycyrrhizae 5g.
The Chinese medicine composition of the complex treatment sheep disease, including following preparation process:
1) sargentodoxa cuneata, cynomorium songaricum crush, and are soaked in solution 1,50 DEG C of heating stirring 4h, are left to ferment 5 days, obtain fermentation material 1, The clear water that 1 times of 1 mass of fermentation material is added decocts 4h, and filtering obtains filtrate 1;
2) matrimony vine, cloves, Cortex Magnoliae Officinalis mixing, high-temperature heating are soaked in 20min in hydrochloric acid solution, and low temperature bakes, and crushes, obtains Powder 1 is spare;
3) hawthorn, Radix Glycyrrhizae, filtrate 1, powder 1 mix, 60 DEG C of stirring 3h, and 1,30 DEG C of standings of extracting solution of 2 times of quality are added 3h, filtering, takes filtrate, obtains filtrate 2, filtrate 2 is prepared into dosage form.
The solution 1 is rice wine, tomato, capsicum, sodium chloride, clear water according to mass ratio 5:2:1:0.5:15 mixing, Ultrasonic extraction, 4 DEG C of standing 3h, 80 DEG C are heated 20min and filtered to obtain the final product.
The fermentation is fermented 3 days under the conditions of 23 DEG C, and 3% milk powder is added, and 30 DEG C ferment 2 days.
The high-temperature heating is to handle 4min under 240 DEG C, 1.5MPa.
The extracting solution 1 is pawpaw, clear water according to mass ratio 3:40 mixing ultrasonications, are inoculated with 1% withered grass gemma Bacillus, normal temperature fermentation 3 days and obtain, filtering and obtain.
Embodiment 2
A kind of Chinese medicine composition of complex treatment sheep disease, includes the raw material of following mass parts meter:Sargentodoxa cuneata 67g, cynomorium songaricum 35g, matrimony vine 30g, 24g parts of hawthorn, cloves 14g, 8 g of Cortex Magnoliae Officinalis, Radix Glycyrrhizae 7g.
The Chinese medicine composition of the complex treatment sheep disease, including following preparation process:
1) sargentodoxa cuneata, cynomorium songaricum crush, and are soaked in solution 1,54 DEG C of heating stirring 5h, are left to ferment 5.7 days, obtain fermentation material 1, the clear water that 1 times of 1 mass of fermentation material is added decocts 4.5h, and filtering obtains filtrate 1;
2) matrimony vine, cloves, Cortex Magnoliae Officinalis mixing, high-temperature heating are soaked in 24min in hydrochloric acid solution, and low temperature bakes, and crushes, obtains Powder 1 is spare;
3) hawthorn, Radix Glycyrrhizae, filtrate 1, powder 1 mix, and 1,33 DEG C of the extracting solution of 2.3 times of quality is added in 62 DEG C of stirring 3.5h 3.5h is stood, filtering takes filtrate, obtains filtrate 2, filtrate 2 is prepared into dosage form.
The solution 1 is rice wine, tomato, capsicum, sodium chloride, clear water according to mass ratio 5.8:2.3:1.2:0.7: 16 mixing, ultrasonic extraction, 5 DEG C of standing 3.-6h, 84 DEG C are heated 24min and filtered to obtain the final product.
The fermentation is fermented 3.4 days under the conditions of 24 DEG C, and 3.5% milk powder is added, and 32 DEG C ferment 2.3 days.
The high-temperature heating is to handle 4.5min under 260 DEG C, 1.7MPa.
The extracting solution 1 is pawpaw, clear water according to mass ratio 3.5:44 mixing ultrasonications, are inoculated with 1.1% withered grass Bacillus, normal temperature fermentation 3.5 days and obtain, filtering and obtain.
Embodiment 3
A kind of Chinese medicine composition of complex treatment sheep disease, sargentodoxa cuneata 74g, cynomorium songaricum 42g, matrimony vine 36g, hawthorn 36g, cloves 20g, Cortex Magnoliae Officinalis 13g, Radix Glycyrrhizae 10g.
The Chinese medicine composition of the complex treatment sheep disease, including following preparation process:
1) sargentodoxa cuneata, cynomorium songaricum crush, and are soaked in solution 1,58 DEG C of heating stirring 6h, are left to ferment 6 days, obtain fermentation material 1, The clear water that 1 times of 1 mass of fermentation material is added decocts 4.8h, and filtering obtains filtrate 1;
2) matrimony vine, cloves, Cortex Magnoliae Officinalis mixing, high-temperature heating are soaked in 26min in hydrochloric acid solution, and low temperature bakes, and crushes, obtains Powder 1 is spare;
3) hawthorn, Radix Glycyrrhizae, filtrate 1, powder 1 mix, 68 DEG C of stirring 4h, and 1,36 DEG C of the extracting solution that 2.7 times of quality are added is quiet 4h is set, is filtered, is taken filtrate, obtain filtrate 2, filtrate 2 is prepared into dosage form.
The solution 1 is rice wine, tomato, capsicum, sodium chloride, clear water according to mass ratio 7:2.7:1.6:0.8:17 Mixing, ultrasonic extraction, 6 DEG C of standing 5h, 86 DEG C are heated 25min and filtered to obtain the final product.
The fermentation is fermented 3.6 days under the conditions of 26 DEG C, and 4% milk powder is added, and 35 DEG C ferment 2.6 days.
The high-temperature heating is to handle 4.7min under 280 DEG C, 2.0MPa.
The extracting solution 1 is pawpaw, clear water according to mass ratio 4:46 mixing ultrasonications, are inoculated with 1.2% withered grass bud Spore bacillus, normal temperature fermentation 4 days and obtain, filtering and obtain.
Embodiment 4
A kind of Chinese medicine composition of complex treatment sheep disease, includes the raw material of following mass parts meter:Sargentodoxa cuneata 80g, cynomorium songaricum 57g, matrimony vine 50g, hawthorn 40g, cloves 28g, Cortex Magnoliae Officinalis 20g, Radix Glycyrrhizae 20g.
The Chinese medicine composition of the complex treatment sheep disease, including following preparation process:
1) sargentodoxa cuneata, cynomorium songaricum crush, and are soaked in solution 1,60 DEG C of heating stirring 7h, are left to ferment 7 days, obtain fermentation material 1, The clear water that 1 times of 1 mass of fermentation material is added decocts 5h, and filtering obtains filtrate 1;
2) matrimony vine, cloves, Cortex Magnoliae Officinalis mixing, high-temperature heating are soaked in 30min in hydrochloric acid solution, and low temperature bakes, and crushes, obtains Powder 1 is spare;
3) hawthorn, Radix Glycyrrhizae, filtrate 1, powder 1 mix, 70 DEG C of stirring 5h, and 0 DEG C of standing of extracting solution Isosorbide-5-Nitrae of 3 times of quality is added 5h, filtering, takes filtrate, obtains filtrate 2, filtrate 2 is prepared into dosage form.
The solution 1 is rice wine, tomato, capsicum, sodium chloride, clear water according to mass ratio 8:3:2:1.3:20 mixing, Ultrasonic extraction, 7 DEG C of standing 6h, 90 DEG C are heated 30min and filtered to obtain the final product.
The fermentation is fermented 4 days under the conditions of 28 DEG C, and 5% milk powder is added, and 37 DEG C ferment 3 days.
The high-temperature heating is to handle 5min under 300 DEG C, 2.4MPa.
The extracting solution 1 is pawpaw, clear water according to mass ratio 5:50 mixing ultrasonications, are inoculated with 1.3% withered grass bud Spore bacillus, normal temperature fermentation 5 days and obtain, filtering and obtain.
Embodiment 5
Difference lies in embodiment 5 is to mix all raw materials to embodiment 5, crushes, added water to cook with embodiment example 2 Filter.
Embodiment 6
Embodiment 6 and the difference of embodiment example 2 exist, and embodiment 6 is added without extracting solution 1, other preparations in preparation process Method is all identical.
Experimental example
1, acute toxicity test
1) subjects:Selection health, weight are randomly divided into 7,1-6 groups to embodiment in comparable small white mouse 140 Medicament prepared by 1-6,7 groups as blank control group hello plain boiled water.
2) test method:After the small white mouse of each experimental group is fed 3 days, each experimental group once uses medicament by oral administration, gives Medicine standard be 6g/kg, to observation post administration mouse in 12h, for 24 hours, 48 h, 5 days, 7 days, the situation after 2 weeks.
3) result:Within the observation period, whole small white mouses do not occur any abnormal conditions, the state of mind of small white mouse, food Desire, secretion, breathing, eyes are identical as control group.Each experimental mice is dissected, each histoorgan is not found Lesion takes mouse core, liver, spleen, lung, kidney, intestines to make pathological section, as a result, it has been found that each organ is normal.The experimental results showed that this hair The medicament of bright preparation, median lethal dose>6g/kg.
2, application effect
1) experimental subjects:It is suitable to randomly select 1400 quality, the comparable sheep of age in days is divided into as experimental subjects 7 groups, 1-6 groups apply medicament prepared by embodiment 1-6,7 blank group of experimental group.
2) application method:By medicament and water in mass ratio 1:30 mixing, obtain admixing medical solutions, dosage according to the weight of sheep into Row calculates, and gives 1g admixing medical solutions, 3 times a week, give by per kg, in addition, medicament can be applied to outer affected part as wound occurs in sheep.Often The cultivation situation of group is all identical, count each group sheep flu, parasitic infection, depilation incidence
3) experimental result:Experimental result is as shown in table 2.
1 application effect of table
Catch a cold incidence % Parasitic infection incidence % The incidence % of depilation
Embodiment 1 5.6 3.1 6.3
Embodiment 2 4.7 2.6 5.6
Embodiment 3 5.0 2.5 5.4
Embodiment 4 5.9 3.8 6.4
Embodiment 5 20 16.3 16.1
Embodiment 6 10 12.7 13.4
Control group 25 19.7 18.4
In addition, during entire sheep cultivates, the sheep of embodiment 1-4 cultivation, appetite is preferable, and the state of mind is good, and digestion is inhaled It keeps well, is newly fast at metabolism, the weight of the sheep of embodiment 1-4 is higher than other control groups 10-15%, mutton when sheep, which reaches, to be delivered for sale Quality also there is improvement, meat to show as succulence, fresh and tender and surface dry, illustrate to improve muscle is waterpower, improves meat Succulence, tenderness is also improved.

Claims (7)

1. a kind of Chinese medicine composition of complex treatment sheep disease, which is characterized in that include the raw material of following mass parts meter:Sargentodoxa cuneata 35-80 parts, 20-57 parts of cynomorium songaricum, 20-50 parts of matrimony vine, 17-40 parts of hawthorn, 10-28 parts of cloves, 5-20 parts of Cortex Magnoliae Officinalis, Radix Glycyrrhizae 5-20 Part.
2. the Chinese medicine composition of complex treatment sheep disease as described in claim 1, which is characterized in that including following mass parts meter Raw material:67-74 parts of sargentodoxa cuneata, 35-42 parts of cynomorium songaricum, 30-36 parts of matrimony vine, 24-36 parts of hawthorn, 14-20 parts of cloves, Cortex Magnoliae Officinalis 8-13 Part, 7-10 parts of Radix Glycyrrhizae.
3. the Chinese medicine composition of complex treatment sheep disease as described in claim 1, which is characterized in that the complex treatment sheep The Chinese medicine composition of disease, including following preparation process:
1) sargentodoxa cuneata, cynomorium songaricum crush, and are soaked in solution 1,50-60 DEG C of heating stirring 4-7h, are left to ferment 5-7 days, must ferment Material 1, the clear water that 1 times of 1 mass of fermentation material is added decoct 4-5h, and filtering obtains filtrate 1;
2) matrimony vine, cloves, Cortex Magnoliae Officinalis mixing, high-temperature heating are soaked in 20-30min in hydrochloric acid solution, and low temperature bakes, and crushes, obtains powder End 1 is spare;
3) hawthorn, Radix Glycyrrhizae, filtrate 1, powder 1 mix, and the extracting solution 1,30-40 of 2-3 times of quality is added in 60-70 DEG C of stirring 3-5h DEG C stand 3-5h, filtering, take filtrate, obtain filtrate 2, filtrate 2 is prepared into dosage form.
4. the Chinese medicine composition of complex treatment sheep disease as claimed in claim 3, which is characterized in that the solution 1 is rice Wine, tomato, capsicum, sodium chloride, clear water are according to mass ratio 5-8:2-3:1-2:0.5-1.3:15-20 is mixed, ultrasonic extraction, 4- 7 DEG C of standing 3-6h, 80-90 DEG C is heated 20-30min and filtered to obtain the final product.
5. the Chinese medicine composition of complex treatment sheep disease as claimed in claim 3, which is characterized in that the fermentation, be It ferments 3-4 days under the conditions of 23-28 DEG C, the milk powder of 3-5% is added, 30-37 DEG C ferments 2-3 days.
6. the Chinese medicine composition of complex treatment sheep disease as claimed in claim 3, which is characterized in that the high-temperature heating, It is to handle 4-5min under 240-300 DEG C, 1.5-2.4MPa.
7. the Chinese medicine composition of complex treatment sheep disease as claimed in claim 3, which is characterized in that the extracting solution 1 is Pawpaw, clear water are according to mass ratio 3-5:40-50 mixing ultrasonications are inoculated with the bacillus subtilis of 1-1.3%, normal temperature fermentation 3- 5 days and obtain, filtering and obtain.
CN201810166283.5A 2018-02-28 2018-02-28 A kind of Chinese medicine composition and preparation method thereof of complex treatment sheep disease Pending CN108355007A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106901001A (en) * 2017-01-23 2017-06-30 六安市绿丰牧业科技有限公司 A kind of sheep feed of anti-disease and preparation method thereof
CN107156750A (en) * 2017-05-22 2017-09-15 凯里市田园食品开发有限公司 A kind of formula of Compound-acid soup, Compound-acid soup and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106901001A (en) * 2017-01-23 2017-06-30 六安市绿丰牧业科技有限公司 A kind of sheep feed of anti-disease and preparation method thereof
CN107156750A (en) * 2017-05-22 2017-09-15 凯里市田园食品开发有限公司 A kind of formula of Compound-acid soup, Compound-acid soup and preparation method thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
李兴如等: "平胃散加减治疗马牛羊消化道疾病", 《中兽医医药杂志》 *
杨生勇等: "中药治疗柴达木绒山羊种公羊阳痿", 《中兽医医药杂志》 *
赵年彪: ""消痹汤"治家畜痹证之我见"", 《湖北畜牧兽医》 *

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Application publication date: 20180803