CN108324650A - A kind of ingredient and preparation method thereof of skin care whitening cream - Google Patents
A kind of ingredient and preparation method thereof of skin care whitening cream Download PDFInfo
- Publication number
- CN108324650A CN108324650A CN201810352652.XA CN201810352652A CN108324650A CN 108324650 A CN108324650 A CN 108324650A CN 201810352652 A CN201810352652 A CN 201810352652A CN 108324650 A CN108324650 A CN 108324650A
- Authority
- CN
- China
- Prior art keywords
- cream
- vacuum
- stirring
- skin care
- extract
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/066—Clavicipitaceae
- A61K36/068—Cordyceps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/51—Gentianaceae (Gentian family)
- A61K36/515—Gentiana
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/748—Oldenlandia or Hedyotis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8994—Coix (Job's tears)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Medical Informatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Alternative & Traditional Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of ingredients and preparation method thereof of skin care whitening cream, are prepared by the following method：（1）Prepare cream dispensing；（2）Configure cream：Contain according to every 100ml creams：Felwort 2%, adlay 1%, the bletilla striata 1%, oldenlandia diffusa 2%, ginkgo leaf 2%, Radix Angelicae Sinensis 1%, radix ampelopsis 1%, Korean ginseng 3%, cordyceps sinensis 3%, essence 0.03%, preservative 0.5~1.5%, thickener 0.5~1.5%, cream matrix 60%, surplus are deionized water.The skin care whitening cream of the present invention is mildly non-stimulated, and skin resistance can be made to enhance naturally, have effects that nature whitening effect can improve skin metabolism and moisturizing, the moisture barrier for reinforcing skin, prevents the generation of the following pigementation.
Description
Technical field
The present invention relates to the ingredients and its preparation side of a kind of skin care whitening cream more particularly to a kind of skin care whitening cream
Method.
Background technology
Skin Cell aging is the basis of skin disease morbidity, therefore anti-aging is both the root problem of beauty, and skin
The key of skin health care.The characteristics of skin care skin-lightening cosmetic is aiming at aging skin and Crack cause, on moisturizing, sun-proof basis
On, addition active nutrients further smooth skin to reinforce skin-nourishing absorption, reach and bag is delayed to remove wrinkle always
Purpose.Have the shortcomings that wrinkle, anti-aging performance are insufficient in existing cosmetics, while there is also various work in cosmetics
The problem that property component goes wrinkle, anti-aging effects unstable caused by storage stability is bad.
The kind of alternative skin whitener is countless on the market, also many as the skin whitener of characteristic using plants herb,
But the Shortcomings such as its stability, whitening effect.
The present invention is intended to provide a kind of ingredient and preparation method thereof of skin care whitening cream, mild non-stimulated, Ke Yiyou
Effect inhibits inflammatory reaction, promotes the reparation of vagina mucosa damage, and has very strong inhibiting effect to candida albicans, to vagina memory
Probiotics then without obvious inhibiting effect, it is possible to prevente effectively from destroying vagina environment.
Invention content
Technical problems based on background technology, the present invention in view of the shortcomings of the current prior art, provide a kind of shield
The ingredient and preparation method thereof of skin whitening cream, it is mild non-stimulated, skin resistance can be made to enhance naturally, there is nature whitening
Effect can improve the effect of skin metabolism and moisturizing, the moisture barrier for reinforcing skin, prevent the following pigementation
Occur.
The extractive matter of adlay, which is added in cosmetics, also can reach sun-proof and antiultraviolet effect, have nature whitening effect
The function of skin metabolism and moisturizing can be improved.Moisture barrier for reinforcing skin prevents the generation of the following pigementation.
Angelica extract, radix ampelopsis extracting solution, with Korean ginseng extracting solution, the cordyceps extracting liquid perfection for improving skin vigor
Ground is combined together, and is effectively excited skin vigor, is kept the health status of skin.
Radix Gentianae extract can be such that skin resistance enhances naturally, while the effect of have both whitening and moisturizing, have releive,
The effect of calm and moisturizing.
The present inventor, by continuously improving formula, develops a kind of skin care whitening cream on a large amount of practical basis
Ingredient.
Technical scheme is as follows：
A kind of ingredient and preparation method thereof of skin care whitening cream, is prepared by the following method：
（1）Prepare cream dispensing：
A, Chinese medicine is weighed into raw material by weight ratio；
The Chinese medicine is by weight ratio：Felwort 10~30%, adlay 10~30%, the bletilla striata 10~20%, oldenlandia diffusa 10~
30%, ginkgo leaf 10~20%, Radix Angelicae Sinensis 10~30%, radix ampelopsis 10~30%, Korean ginseng 10~30%, cordyceps sinensis 10~30%, sterilizing
It is spare；
B, Chinese medical extract is prepared, extract liquor is obtained；
Extraction process：Percent by volume is that 75%~80% ethyl alcohol extracts twice, extracts bulk pharmaceutical chemicals and ethyl alcohol quality volume for the first time
It is 1 than g/ml：10~1：20,60 DEG C~70 DEG C heating stirrings 1~2 hour, filter to obtain first time filtrate；Second of extraction raw material
Medicine is 1 with ethyl alcohol mass volume ratio g/ml：10~1：20,60 DEG C~70 DEG C heating stirring 30min~60min, filter second
Secondary filtrate；First time filtrate and second of filtrate mixing, are concentrated into 0.2~0.5g/ml, obtain concentrate；
Fermentation parameter：38 DEG C, control starting pH:6.5, ferment pH:5.0, speed of agitator：100r/min；It ferments after 2h, is cooled to
10 DEG C, 100~120min is kept, then proceedes to appreciate and continues 5~8h of fermentation to 40 DEG C；
C, Chinese medicine extract liquor is mixed and is added in cream matrix, obtain mixing cream：
The cream matrix component weight percent composition：Hexadecanyl phosphate potassium 0.5~2%, niacinamide 0.1~0.2%,
Methyl hydroxybenzoate 0.05~0.1%, hydrogenated coco 0.03~0.35%, polyglycereol~10 6~10, butanediol 0.35~0.9%, meat
Cardanol 0.05~0.4%, Sodium Hyaluronate 0.01~0.08, stearine 0.04~0.25%, cetostearyl alcohol
0.04~0.25%, stearyl alcohol 0.04~0.3%, dimethyl silicone polymer 0.03~0.35%, dimethicone 0.5~1.5,
Xylitol 0.06~0.45%, hydroxyacetic acid 0.05~0.3%, xanthans 0.12~0.45%, cholesterine 0.03~0.4%,
Hydrolytic collagen 0.03~0.3%, soluble elastin 0.025~0.4%, heartsease extract 0.12~0.3%, plant ammonia
Base acids 0.06~0.4%, pentapeptide~1 0.02~0.2%, methylisothiazolinone 0.1%；Propolis extract 0.1~0.3%,
Imidazolidinyl urea 0.02~0.35%, essence 0.02~0.04%, preservative 0.5~1.5%, thickener 0.5~1.5%, it is remaining
Amount is deionized water；
D, mixing cream is sufficiently stirred, mixed：
Chinese medicine extract liquor, cream matrix are separately added into deionized water, are stirring evenly and then adding into essence 0.02~0.04%, thickening
0.5~1.5% mixture of agent, successively puts into corresponding reaction kettle, then begins to warm up, and is opened when reaching certain flowing shape
Stirring, heats while stirring, is slowly heated to 80 DEG C -85 DEG C, stops heating when raw material being made to be completely dissolved, is slowly stirred to cold
But；
Mixing parametric：Speed of agitator：2000-3000 revs/min, mixing time：5min-10min, stirring cooling, rate
30-50 revs/min, rate of temperature fall is 1-2 DEG C/min；
E, it emulsifies：
The vacuum system for opening vacuum emulsification pot, makes vacuum emulsification pot be in the vacuum state of vacuum degree -0.07MPa, will react
Raw material in kettle is emulsified by vacuum suck in pot, keeps the temperature in vacuum emulsification pot at 80 DEG C -85 DEG C, is then turned on true
Sky emulsification pot blender carries out homogeneous stirring, and homogeneous speed of agitator 2500r/min stirs 4min；
（2）Configure cream：
Contain according to every 100ml creams：It is felwort 2%, adlay 1%, the bletilla striata 1%, oldenlandia diffusa 2%, ginkgo leaf 2%, Radix Angelicae Sinensis 1%, white
Liana 1%, Korean ginseng 3%, cordyceps sinensis 3%, essence 0.03%, preservative 0.5~1.5%, thickener 0.5~1.5%, cream base
Matter 60%, surplus are deionized water.
The thickener ingredients include polyacrylamide, the isoparaffins of C13~14, the Pareths -6 of C9~11.
2%~6% emulsifier is added in the vacuum emulsification pot, carries out co-emulsifier.
The Chinese medical extract ingredient include product felwort, adlay, the bletilla striata, oldenlandia diffusa, ginkgo leaf, Radix Angelicae Sinensis, radix ampelopsis,
The relative density of Korean ginseng, cordyceps extracting liquid, the Chinese medical extract of the extraction is 0.9-1.1.
Preferably, continuing stirring cooling, the vacuum system of vacuum emulsification pot is opened simultaneously, vacuum emulsification pot is made to be in true
The vacuum state of reciprocal of duty cycle -0.07MPa.Bubble in material is extracted.When material temperature is down to 35 DEG C, stops stirring and put vacuum breast
Change the vacuum degree of pot, discharging obtains cream.
The invention has the beneficial effects that：
A kind of ingredient and preparation method thereof of skin care whitening cream is provided, it is mild non-stimulated, skin resistance can be made to increase naturally
By force, have effects that nature whitening effect can improve skin metabolism and moisturizing, the moisture barrier for reinforcing skin prevents
The generation of the following pigementation.
Specific implementation mode
The extracting solution that all embodiments of the invention are used is purchased from arbitrary company, and many producers are in stock.
The experiment of the present invention is completed in laboratory.
Embodiment 1：
Prepare cream dispensing：
A, Chinese medicine is weighed into raw material by weight ratio；
The Chinese medicine is by weight ratio：Felwort 15%, adlay 10%, the bletilla striata 10%, oldenlandia diffusa 15%, ginkgo leaf 10%, when
Return 10%, radix ampelopsis 10%, Korean ginseng 10%, cordyceps sinensis 10%, sterilizing spare；
B, Chinese medical extract is prepared, extract liquor is obtained；
Extraction process：Percent by volume is that 75%~80% ethyl alcohol extracts twice, extracts bulk pharmaceutical chemicals and ethyl alcohol quality volume for the first time
It is 1 than g/ml：10~1：20,60 DEG C~70 DEG C heating stirrings 1~2 hour, filter to obtain first time filtrate；Second of extraction raw material
Medicine is 1 with ethyl alcohol mass volume ratio g/ml：10~1：20,60 DEG C~70 DEG C heating stirring 30min~60min, filter second
Secondary filtrate；First time filtrate and second of filtrate mixing, are concentrated into 0.2~0.5g/ml, obtain concentrate；
Fermentation parameter：38 DEG C, control starting pH:6.5, ferment pH:5.0, speed of agitator：100r/min；It ferments after 2h, is cooled to
10 DEG C, 100~120min is kept, then proceedes to appreciate and continues 5~8h of fermentation to 40 DEG C；
C, Chinese medicine extract liquor is mixed and is added in cream matrix, obtain mixing cream：
The cream matrix component weight percent composition：Hexadecanyl phosphate potassium 0.5~2%, niacinamide 0.1~0.2%,
Methyl hydroxybenzoate 0.05~0.1%, hydrogenated coco 0.03~0.35%, polyglycereol~10 6~10, butanediol 0.35~0.9%, meat
Cardanol 0.05~0.4%, Sodium Hyaluronate 0.01~0.08, stearine 0.04~0.25%, cetostearyl alcohol
0.04~0.25%, stearyl alcohol 0.04~0.3%, dimethyl silicone polymer 0.03~0.35%, dimethicone 0.5~1.5,
Xylitol 0.06~0.45%, hydroxyacetic acid 0.05~0.3%, xanthans 0.12~0.45%, cholesterine 0.03~0.4%,
Hydrolytic collagen 0.03~0.3%, soluble elastin 0.025~0.4%, heartsease extract 0.12~0.3%, plant ammonia
Base acids 0.06~0.4%, pentapeptide~1 0.02~0.2%, methylisothiazolinone 0.1%；Propolis extract 0.1~0.3%,
Imidazolidinyl urea 0.02~0.35%, essence 0.02~0.04%, preservative 0.5~1.5%, thickener 0.5~1.5%, it is remaining
Amount is deionized water；
D, mixing cream is sufficiently stirred, mixed：
Chinese medicine extract liquor, cream matrix are separately added into deionized water, are stirring evenly and then adding into essence 0.02~0.04%, thickening
0.5~1.5% mixture of agent, successively puts into corresponding reaction kettle, then begins to warm up, and is opened when reaching certain flowing shape
Stirring, heats while stirring, is slowly heated to 80 DEG C -85 DEG C, stops heating when raw material being made to be completely dissolved, is slowly stirred to cold
But；
Mixing parametric：Speed of agitator：2000-3000 revs/min, mixing time：5min-10min, stirring cooling, rate
30-50 revs/min, rate of temperature fall is 1-2 DEG C/min；
E, it emulsifies：
The vacuum system for opening vacuum emulsification pot, makes vacuum emulsification pot be in the vacuum state of vacuum degree -0.07MPa, will react
Raw material in kettle is emulsified by vacuum suck in pot, keeps the temperature in vacuum emulsification pot at 80 DEG C -85 DEG C, is then turned on true
Sky emulsification pot blender carries out homogeneous stirring, and homogeneous speed of agitator 2500r/min stirs 4min；
Embodiment 2：
Prepare cream dispensing：
A, Chinese medicine is weighed into raw material by weight ratio；
The Chinese medicine is by weight ratio：Felwort 10%, adlay 10%, the bletilla striata 10%, oldenlandia diffusa 10%, ginkgo leaf 10%, when
Return 15%, radix ampelopsis 15%, Korean ginseng 10%, cordyceps sinensis 10%, sterilizing spare；
B, Chinese medical extract is prepared, extract liquor is obtained；
Extraction process：Percent by volume is that 75%~80% ethyl alcohol extracts twice, extracts bulk pharmaceutical chemicals and ethyl alcohol quality volume for the first time
It is 1 than g/ml：10~1：20,60 DEG C~70 DEG C heating stirrings 1~2 hour, filter to obtain first time filtrate；Second of extraction raw material
Medicine is 1 with ethyl alcohol mass volume ratio g/ml：10~1：20,60 DEG C~70 DEG C heating stirring 30min~60min, filter second
Secondary filtrate；First time filtrate and second of filtrate mixing, are concentrated into 0.2~0.5g/ml, obtain concentrate；
Fermentation parameter：38 DEG C, control starting pH:6.5, ferment pH:5.0, speed of agitator：100r/min；It ferments after 2h, is cooled to
10 DEG C, 100~120min is kept, then proceedes to appreciate and continues 5~8h of fermentation to 40 DEG C；
C, Chinese medicine extract liquor is mixed and is added in cream matrix, obtain mixing cream：
The cream matrix component weight percent composition：Hexadecanyl phosphate potassium 0.5~2%, niacinamide 0.1~0.2%,
Methyl hydroxybenzoate 0.05~0.1%, hydrogenated coco 0.03~0.35%, polyglycereol~10 6~10, butanediol 0.35~0.9%, meat
Cardanol 0.05~0.4%, Sodium Hyaluronate 0.01~0.08, stearine 0.04~0.25%, cetostearyl alcohol
0.04~0.25%, stearyl alcohol 0.04~0.3%, dimethyl silicone polymer 0.03~0.35%, dimethicone 0.5~1.5,
Xylitol 0.06~0.45%, hydroxyacetic acid 0.05~0.3%, xanthans 0.12~0.45%, cholesterine 0.03~0.4%,
Hydrolytic collagen 0.03~0.3%, soluble elastin 0.025~0.4%, heartsease extract 0.12~0.3%, plant ammonia
Base acids 0.06~0.4%, pentapeptide~1 0.02~0.2%, methylisothiazolinone 0.1%；Propolis extract 0.1~0.3%,
Imidazolidinyl urea 0.02~0.35%, essence 0.02~0.04%, preservative 0.5~1.5%, thickener 0.5~1.5%, it is remaining
Amount is deionized water；
D, mixing cream is sufficiently stirred, mixed：
Chinese medicine extract liquor, cream matrix are separately added into deionized water, are stirring evenly and then adding into essence 0.02~0.04%, thickening
0.5~1.5% mixture of agent, successively puts into corresponding reaction kettle, then begins to warm up, and is opened when reaching certain flowing shape
Stirring, heats while stirring, is slowly heated to 80 DEG C -85 DEG C, stops heating when raw material being made to be completely dissolved, is slowly stirred to cold
But；
Mixing parametric：Speed of agitator：2000-3000 revs/min, mixing time：5min-10min, stirring cooling, rate
30-50 revs/min, rate of temperature fall is 1-2 DEG C/min；
E, it emulsifies：
The vacuum system for opening vacuum emulsification pot, makes vacuum emulsification pot be in the vacuum state of vacuum degree -0.07MPa, will react
Raw material in kettle is emulsified by vacuum suck in pot, keeps the temperature in vacuum emulsification pot at 80 DEG C -85 DEG C, is then turned on true
Sky emulsification pot blender carries out homogeneous stirring, and homogeneous speed of agitator 2500r/min stirs 4min；
Embodiment 3：
Prepare cream dispensing：
A, Chinese medicine is weighed into raw material by weight ratio；
The Chinese medicine is by weight ratio：Felwort 10%, adlay 10%, the bletilla striata 10%, oldenlandia diffusa 10%, ginkgo leaf 10%, when
Return 10%, radix ampelopsis 10%, Korean ginseng 15%, cordyceps sinensis 15%, sterilizing spare；
B, Chinese medical extract is prepared, extract liquor is obtained；
Extraction process：Percent by volume is that 75%~80% ethyl alcohol extracts twice, extracts bulk pharmaceutical chemicals and ethyl alcohol quality volume for the first time
It is 1 than g/ml：10~1：20,60 DEG C~70 DEG C heating stirrings 1~2 hour, filter to obtain first time filtrate；Second of extraction raw material
Medicine is 1 with ethyl alcohol mass volume ratio g/ml：10~1：20,60 DEG C~70 DEG C heating stirring 30min~60min, filter second
Secondary filtrate；First time filtrate and second of filtrate mixing, are concentrated into 0.2~0.5g/ml, obtain concentrate；
Fermentation parameter：38 DEG C, control starting pH:6.5, ferment pH:5.0, speed of agitator：100r/min；It ferments after 2h, is cooled to
10 DEG C, 100~120min is kept, then proceedes to appreciate and continues 5~8h of fermentation to 40 DEG C；
C, Chinese medicine extract liquor is mixed and is added in cream matrix, obtain mixing cream：
The cream matrix component weight percent composition：Hexadecanyl phosphate potassium 0.5~2%, niacinamide 0.1~0.2%,
Methyl hydroxybenzoate 0.05~0.1%, hydrogenated coco 0.03~0.35%, polyglycereol~10 6~10, butanediol 0.35~0.9%, meat
Cardanol 0.05~0.4%, Sodium Hyaluronate 0.01~0.08, stearine 0.04~0.25%, cetostearyl alcohol
0.04~0.25%, stearyl alcohol 0.04~0.3%, dimethyl silicone polymer 0.03~0.35%, dimethicone 0.5~1.5,
Xylitol 0.06~0.45%, hydroxyacetic acid 0.05~0.3%, xanthans 0.12~0.45%, cholesterine 0.03~0.4%,
Hydrolytic collagen 0.03~0.3%, soluble elastin 0.025~0.4%, heartsease extract 0.12~0.3%, plant ammonia
Base acids 0.06~0.4%, pentapeptide~1 0.02~0.2%, methylisothiazolinone 0.1%；Propolis extract 0.1~0.3%,
Imidazolidinyl urea 0.02~0.35%, essence 0.02~0.04%, preservative 0.5~1.5%, thickener 0.5~1.5%, it is remaining
Amount is deionized water；
D, mixing cream is sufficiently stirred, mixed：
Chinese medicine extract liquor, cream matrix are separately added into deionized water, are stirring evenly and then adding into essence 0.02~0.04%, thickening
0.5~1.5% mixture of agent, successively puts into corresponding reaction kettle, then begins to warm up, and is opened when reaching certain flowing shape
Stirring, heats while stirring, is slowly heated to 80 DEG C -85 DEG C, stops heating when raw material being made to be completely dissolved, is slowly stirred to cold
But；
Mixing parametric：Speed of agitator：2000-3000 revs/min, mixing time：5min-10min, stirring cooling, rate
30-50 revs/min, rate of temperature fall is 1-2 DEG C/min；
E, it emulsifies：
The vacuum system for opening vacuum emulsification pot, makes vacuum emulsification pot be in the vacuum state of vacuum degree -0.07MPa, will react
Raw material in kettle is emulsified by vacuum suck in pot, keeps the temperature in vacuum emulsification pot at 80 DEG C -85 DEG C, is then turned on true
Sky emulsification pot blender carries out homogeneous stirring, and homogeneous speed of agitator 2500r/min stirs 4min；
Embodiment 4：
It is not added with Cordyceps extract：
A, Chinese medicine is weighed into raw material by weight ratio；
The Chinese medicine is by weight ratio：Felwort 10~30, adlay 10~30, the bletilla striata 10~20, oldenlandia diffusa 10~30,
Ginkgo leaf 10~20, Radix Angelicae Sinensis 10~30, radix ampelopsis 10~30, Korean ginseng 10~30, sterilizing are spare；
B, Chinese medical extract is prepared, extract liquor is obtained；
Extraction process：Percent by volume is that 75%~80% ethyl alcohol extracts twice, extracts bulk pharmaceutical chemicals and ethyl alcohol quality volume for the first time
It is 1 than g/ml：10~1：20,60 DEG C~70 DEG C heating stirrings 1~2 hour, filter to obtain first time filtrate；Second of extraction raw material
Medicine is 1 with ethyl alcohol mass volume ratio g/ml：10~1：20,60 DEG C~70 DEG C heating stirring 30min~60min, filter second
Secondary filtrate；First time filtrate and second of filtrate mixing, are concentrated into 0.2~0.5g/ml, obtain concentrate；
Fermentation parameter：38 DEG C, control starting pH:6.5, ferment pH:5.0, speed of agitator：100r/min；It ferments after 2h, is cooled to
10 DEG C, 100~120min is kept, then proceedes to appreciate and continues 5~8h of fermentation to 40 DEG C；
C, Chinese medicine extract liquor is mixed and is added in cream matrix, obtain mixing cream：
The cream matrix component weight percent composition：Hexadecanyl phosphate potassium 0.5~2%, niacinamide 0.1~0.2%,
Methyl hydroxybenzoate 0.05~0.1%, hydrogenated coco 0.03~0.35%, polyglycereol~10 6~10, butanediol 0.35~0.9%, meat
Cardanol 0.05~0.4%, Sodium Hyaluronate 0.01~0.08, stearine 0.04~0.25%, cetostearyl alcohol
0.04~0.25%, stearyl alcohol 0.04~0.3%, dimethyl silicone polymer 0.03~0.35%, dimethicone 0.5~1.5,
Xylitol 0.06~0.45%, hydroxyacetic acid 0.05~0.3%, xanthans 0.12~0.45%, cholesterine 0.03~0.4%,
Hydrolytic collagen 0.03~0.3%, soluble elastin 0.025~0.4%, heartsease extract 0.12~0.3%, plant ammonia
Base acids 0.06~0.4%, pentapeptide~1 0.02~0.2%, methylisothiazolinone 0.1%；Propolis extract 0.1~0.3%,
Imidazolidinyl urea 0.02~0.35%, essence 0.02~0.04%, preservative 0.5~1.5%, thickener 0.5~1.5%, it is remaining
Amount is deionized water；
D, mixing cream is sufficiently stirred, mixed：
Chinese medicine extract liquor, cream matrix are separately added into deionized water, are stirring evenly and then adding into essence 0.02~0.04%, thickening
0.5~1.5% mixture of agent, successively puts into corresponding reaction kettle, then begins to warm up, and is opened when reaching certain flowing shape
Stirring, heats while stirring, is slowly heated to 80 DEG C -85 DEG C, stops heating when raw material being made to be completely dissolved, is slowly stirred to cold
But；
Mixing parametric：Speed of agitator：2000-3000 revs/min, mixing time：5min-10min, stirring cooling, rate
30-50 revs/min, rate of temperature fall is 1-2 DEG C/min；
E, it emulsifies：
The vacuum system for opening vacuum emulsification pot, makes vacuum emulsification pot be in the vacuum state of vacuum degree -0.07MPa, will react
Raw material in kettle is emulsified by vacuum suck in pot, keeps the temperature in vacuum emulsification pot at 80 DEG C -85 DEG C, is then turned on true
Sky emulsification pot blender carries out homogeneous stirring, and homogeneous speed of agitator 2500r/min stirs 4min；
Embodiment 5：
It is not added with Radix Gentianae extract：
Prepare cream dispensing：
A, Chinese medicine is weighed into raw material by weight ratio；
The Chinese medicine is by weight ratio：Adlay 10~30, the bletilla striata 10~20, oldenlandia diffusa 10~30, ginkgo leaf 10~20,
Radix Angelicae Sinensis 10~30, radix ampelopsis 10~30, Korean ginseng 10~30, cordyceps sinensis 10~30, sterilizing are spare；
B, Chinese medical extract is prepared, extract liquor is obtained；
Extraction process：Percent by volume is that 75%~80% ethyl alcohol extracts twice, extracts bulk pharmaceutical chemicals and ethyl alcohol quality volume for the first time
It is 1 than g/ml：10~1：20,60 DEG C~70 DEG C heating stirrings 1~2 hour, filter to obtain first time filtrate；Second of extraction raw material
Medicine is 1 with ethyl alcohol mass volume ratio g/ml：10~1：20,60 DEG C~70 DEG C heating stirring 30min~60min, filter second
Secondary filtrate；First time filtrate and second of filtrate mixing, are concentrated into 0.2~0.5g/ml, obtain concentrate；
Fermentation parameter：38 DEG C, control starting pH:6.5, ferment pH:5.0, speed of agitator：100r/min；It ferments after 2h, is cooled to
10 DEG C, 100~120min is kept, then proceedes to appreciate and continues 5~8h of fermentation to 40 DEG C；
C, Chinese medicine extract liquor is mixed and is added in cream matrix, obtain mixing cream：
The cream matrix component weight percent composition：Hexadecanyl phosphate potassium 0.5~2%, niacinamide 0.1~0.2%,
Methyl hydroxybenzoate 0.05~0.1%, hydrogenated coco 0.03~0.35%, polyglycereol~10 6~10, butanediol 0.35~0.9%, meat
Cardanol 0.05~0.4%, Sodium Hyaluronate 0.01~0.08, stearine 0.04~0.25%, cetostearyl alcohol
0.04~0.25%, stearyl alcohol 0.04~0.3%, dimethyl silicone polymer 0.03~0.35%, dimethicone 0.5~1.5,
Xylitol 0.06~0.45%, hydroxyacetic acid 0.05~0.3%, xanthans 0.12~0.45%, cholesterine 0.03~0.4%,
Hydrolytic collagen 0.03~0.3%, soluble elastin 0.025~0.4%, heartsease extract 0.12~0.3%, plant ammonia
Base acids 0.06~0.4%, pentapeptide~1 0.02~0.2%, methylisothiazolinone 0.1%；Propolis extract 0.1~0.3%,
Imidazolidinyl urea 0.02~0.35%, essence 0.02~0.04%, preservative 0.5~1.5%, thickener 0.5~1.5%, it is remaining
Amount is deionized water；
D, mixing cream is sufficiently stirred, mixed：
Chinese medicine extract liquor, cream matrix are separately added into deionized water, are stirring evenly and then adding into essence 0.02~0.04%, thickening
0.5~1.5% mixture of agent, successively puts into corresponding reaction kettle, then begins to warm up, and is opened when reaching certain flowing shape
Stirring, heats while stirring, is slowly heated to 80 DEG C -85 DEG C, stops heating when raw material being made to be completely dissolved, is slowly stirred to cold
But；
Mixing parametric：Speed of agitator：2000-3000 revs/min, mixing time：5min-10min, stirring cooling, rate
30-50 revs/min, rate of temperature fall is 1-2 DEG C/min；
E, it emulsifies：
The vacuum system for opening vacuum emulsification pot, makes vacuum emulsification pot be in the vacuum state of vacuum degree -0.07MPa, will react
Raw material in kettle is emulsified by vacuum suck in pot, keeps the temperature in vacuum emulsification pot at 80 DEG C -85 DEG C, is then turned on true
Sky emulsification pot blender carries out homogeneous stirring, and homogeneous speed of agitator 2500r/min stirs 4min；
Embodiment 6：
Using ferment at constant temperature：
Prepare cream dispensing：
A, Chinese medicine is weighed into raw material by weight ratio；
The Chinese medicine is by weight ratio：Felwort 10~30%, adlay 10~30%, the bletilla striata 10~20%, oldenlandia diffusa 10~
30%, ginkgo leaf 10~20%, Radix Angelicae Sinensis 10~30%, radix ampelopsis 10~30%, Korean ginseng 10~30%, cordyceps sinensis 10~30%, sterilizing
It is spare；
B, Chinese medical extract is prepared, extract liquor is obtained；
Extraction process：Percent by volume is that 75%~80% ethyl alcohol extracts twice, extracts bulk pharmaceutical chemicals and ethyl alcohol quality volume for the first time
It is 1 than g/ml：10~1：20, it stirs 1~2 hour, filters to obtain first time filtrate；Second of extraction bulk pharmaceutical chemicals and ethyl alcohol mass body
Product is 1 than g/ml：10~1：20,30min~60min is stirred, second of filtrate is filtered to obtain；First time filtrate and second of filtrate
Mixing, is concentrated into 0.2~0.5g/ml, obtains concentrate；
Fermentation parameter：38 DEG C, control starting pH:6.5, ferment pH:5.0, speed of agitator：100r/min；It ferments after 2h, keeps
100~120min continues 5~8h of fermentation；
C, Chinese medicine extract liquor is mixed and is added in cream matrix, obtain mixing cream：
The cream matrix component weight percent composition：Hexadecanyl phosphate potassium 0.5~2%, niacinamide 0.1~0.2%,
Methyl hydroxybenzoate 0.05~0.1%, hydrogenated coco 0.03~0.35%, polyglycereol~10 6~10, butanediol 0.35~0.9%, meat
Cardanol 0.05~0.4%, Sodium Hyaluronate 0.01~0.08, stearine 0.04~0.25%, cetostearyl alcohol
0.04~0.25%, stearyl alcohol 0.04~0.3%, dimethyl silicone polymer 0.03~0.35%, dimethicone 0.5~1.5,
Xylitol 0.06~0.45%, hydroxyacetic acid 0.05~0.3%, xanthans 0.12~0.45%, cholesterine 0.03~0.4%,
Hydrolytic collagen 0.03~0.3%, soluble elastin 0.025~0.4%, heartsease extract 0.12~0.3%, plant ammonia
Base acids 0.06~0.4%, pentapeptide~1 0.02~0.2%, methylisothiazolinone 0.1%；Propolis extract 0.1~0.3%,
Imidazolidinyl urea 0.02~0.35%, essence 0.02~0.04%, preservative 0.5~1.5%, thickener 0.5~1.5%, it is remaining
Amount is deionized water；
D, mixing cream is sufficiently stirred, mixed：
Chinese medicine extract liquor, cream matrix are separately added into deionized water, are stirring evenly and then adding into essence 0.02~0.04%, thickening
0.5~1.5% mixture of agent, successively puts into corresponding reaction kettle, then begins to warm up, and is opened when reaching certain flowing shape
Stirring, heats while stirring, is slowly heated to 80 DEG C -85 DEG C, stops heating when raw material being made to be completely dissolved, is slowly stirred to cold
But；
Mixing parametric：Speed of agitator：2000-3000 revs/min, mixing time：5min-10min, stirring cooling, rate
30-50 revs/min, rate of temperature fall is 1-2 DEG C/min；
E, it emulsifies：
The vacuum system for opening vacuum emulsification pot, makes vacuum emulsification pot be in the vacuum state of vacuum degree -0.07MPa, will react
Raw material in kettle is emulsified by vacuum suck in pot, keeps the temperature in vacuum emulsification pot at 80 DEG C -85 DEG C, is then turned on true
Sky emulsification pot blender carries out homogeneous stirring, and homogeneous speed of agitator 2500r/min stirs 4min；
7 effect of embodiment measures：
1. skin care whitening effect
In-vitro evaluation tests the assessment for being mainly used for new raw material or formula, is convenient for the effect of early detection substance to be evaluated, also may be used
It is measured with understanding its cytotoxic effect size and effect, the blindness of R＆D process and unnecessary throwing can be reduced in this way
Enter.Experiment in vitro answers the committed step of skin care whitening effect to be designed.
After person on probation washes one's face sooner or later daily, face Xu smears and massages 10-15 minutes the said goods, after trying out 2 weeks, assessment
As a result as follows：
Table 1
| It goes to wrinkle anti-oxidant | Whitening spot-removing | |
| Embodiment 1 | Face wrinkles obviously cut down | Color spot obviously weakens |
| Embodiment 2 | Face wrinkles obviously cut down | Color spot obviously weakens |
| Embodiment 3 | Face wrinkles obviously cut down | Color spot obviously weakens |
| Embodiment 4 | Face wrinkles cut down unobvious | The apparent unobvious of color spot |
| Embodiment 5 | Face wrinkles cut down unobvious | The apparent unobvious of color spot |
| Embodiment 6 | Face wrinkles cut down unobvious | The apparent unobvious of color spot |
As it can be seen that Cordyceps extract and Radix Gentianae extract is added, special zymotechnique is set and plays significant collaboration
Effect, greatly strengthens the whitening spot-removing of skin care whitening cream and crease-resistant effect.
Stability：
After placing 3 months, it is subjected to the same test, the skin care white-skinned face function of Examples 1 to 3 has almost no change, this proof can
It is stored with stablizing.
Bacillus acidi lactici fungistatic effect is tested and assessed：
Bacillus acidi lactici bacteriostatic test is carried out using Odontothrips loti.The Oxford cup of a diameter of 8mm is placed, Examples 1 to 6 synthesis is added
Lactobacillus rhamnosus fermentation lysates.It is put into:It is cultivated in 37 DEG C of incubators for 24 hours, with vernier caliper measurement antibacterial circle diameter.
Test result is shown in Table 2：
Table 2
| Antibacterial circle diameter（mm） | |
| Embodiment 1 | 9.9 |
| Embodiment 2 | 3.5 |
| Embodiment 3 | 4.2 |
| Embodiment 4 | 9.9 |
| Embodiment 5 | 10.1 |
| Embodiment 6 | 9.9 |
Can significantly it find out from upper table, after compounding, Lactobacillus rhamnosus fermentation lysates of the invention are to Bacillus acidi lactici
Toxic action very little, it is not easy to cause vagina disruption of ecological balance.
Toxicology is tested：
Mouse is selected to carry out toxicology test, as a result：
Under 25 % aqueous solutions：
Acute oral toxicity：It is nontoxic
Eye irritation：It is resistant to very much
Sensitization test (STT)：Without sensitization
Single epidermis patch test：Fabulous tolerance
To 3T3~NRU 3T3 fibroblast red untakes Phototoxicity experiment (assessment phototoxicity)：Without phototoxicity.
The results show that a kind of skin care whitening cream of the present invention has very excellent skin-tolerant, acceptance nontoxic
Not sensitization.
Embodiment 8：
Configure cream：
Contain according to every 100ml creams：It is felwort 2%, adlay 1%, the bletilla striata 1%, oldenlandia diffusa 2%, ginkgo leaf 2%, Radix Angelicae Sinensis 1%, white
Liana 1%, Korean ginseng 3%, cordyceps sinensis 3%, essence 0.03%, preservative 0.5~1.5%, thickener 0.5~1.5%, cream base
Matter 60%, surplus are deionized water；
The thickener ingredients include polyacrylamide, the isoparaffins of C13~14, the Pareths -6 of C9~11.
2%~6% emulsifier is added in the vacuum emulsification pot, carries out co-emulsifier.
The Chinese medical extract ingredient include product felwort, adlay, the bletilla striata, oldenlandia diffusa, ginkgo leaf, Radix Angelicae Sinensis, radix ampelopsis,
The relative density of Korean ginseng, cordyceps extracting liquid, the Chinese medical extract of the extraction is 0.9-1.1.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto,
Any one skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its
Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.
Claims (5)
1. a kind of ingredient and preparation method thereof of skin care whitening cream, is prepared by the following method：
（1）Prepare cream dispensing：
A, Chinese medicine is weighed into raw material by weight ratio；
The Chinese medicine is by weight ratio：Felwort 10~30%, adlay 10~30%, the bletilla striata 10~20%, oldenlandia diffusa 10~
30%, ginkgo leaf 10~20%, Radix Angelicae Sinensis 10~30%, radix ampelopsis 10~30%, Korean ginseng 10~30%, cordyceps sinensis 10~30%, sterilizing
It is spare；
B, Chinese medical extract is prepared, extract liquor is obtained；
Extraction process：Percent by volume is that 75%~80% ethyl alcohol extracts twice, extracts bulk pharmaceutical chemicals and ethyl alcohol quality volume for the first time
It is 1 than g/ml：10~1：20,60 DEG C~70 DEG C heating stirrings 1~2 hour, filter to obtain first time filtrate；Second of extraction raw material
Medicine is 1 with ethyl alcohol mass volume ratio g/ml：10~1：20,60 DEG C~70 DEG C heating stirring 30min~60min, filter second
Secondary filtrate；First time filtrate and second of filtrate mixing, are concentrated into 0.2~0.5g/ml, obtain concentrate；
Fermentation parameter：38 DEG C, control starting pH:6.5, ferment pH:5.0, speed of agitator：100r/min；It ferments after 2h, is cooled to
10 DEG C, 100~120min is kept, then proceedes to appreciate and continues 5~8h of fermentation to 40 DEG C；
C, Chinese medicine extract liquor is mixed and is added in cream matrix, obtain mixing cream：
The cream matrix component weight percent composition：Hexadecanyl phosphate potassium 0.5~2%, niacinamide 0.1~0.2%,
Methyl hydroxybenzoate 0.05~0.1%, hydrogenated coco 0.03~0.35%, polyglycereol~10 6~10, butanediol 0.35~0.9%, meat
Cardanol 0.05~0.4%, Sodium Hyaluronate 0.01~0.08, stearine 0.04~0.25%, cetostearyl alcohol
0.04~0.25%, stearyl alcohol 0.04~0.3%, dimethyl silicone polymer 0.03~0.35%, dimethicone 0.5~1.5,
Xylitol 0.06~0.45%, hydroxyacetic acid 0.05~0.3%, xanthans 0.12~0.45%, cholesterine 0.03~0.4%,
Hydrolytic collagen 0.03~0.3%, soluble elastin 0.025~0.4%, heartsease extract 0.12~0.3%, plant ammonia
Base acids 0.06~0.4%, pentapeptide~1 0.02~0.2%, methylisothiazolinone 0.1%；Propolis extract 0.1~0.3%,
Imidazolidinyl urea 0.02~0.35%, essence 0.02~0.04%, preservative 0.5~1.5%, thickener 0.5~1.5%, it is remaining
Amount is deionized water；
D, mixing cream is sufficiently stirred, mixed：
Chinese medicine extract liquor, cream matrix are separately added into deionized water, are stirring evenly and then adding into essence 0.02~0.04%, thickening
0.5~1.5% mixture of agent, successively puts into corresponding reaction kettle, then begins to warm up, and is opened when reaching certain flowing shape
Stirring, heats while stirring, is slowly heated to 80 DEG C -85 DEG C, stops heating when raw material being made to be completely dissolved, is slowly stirred to cold
But；
Mixing parametric：Speed of agitator：2000-3000 revs/min, mixing time：5min-10min, stirring cooling, rate
30-50 revs/min, rate of temperature fall is 1-2 DEG C/min；
E, it emulsifies：
The vacuum system for opening vacuum emulsification pot, makes vacuum emulsification pot be in the vacuum state of vacuum degree -0.07MPa, will react
Raw material in kettle is emulsified by vacuum suck in pot, keeps the temperature in vacuum emulsification pot at 80 DEG C -85 DEG C, is then turned on true
Sky emulsification pot blender carries out homogeneous stirring, and homogeneous speed of agitator 2500r/min stirs 4min；
（2）Configure cream：
Preferably, continuing stirring cooling, the vacuum system of vacuum emulsification pot is opened simultaneously, vacuum emulsification pot is made to be in vacuum
The vacuum state of degree -0.07MPa extracts the bubble in material, when material temperature is down to 35 DEG C, stops stirring and puts vacuum emulsification
The vacuum degree of pot, discharging obtain cream.
2. a kind of skin care whitening cream according to claim 1, it is characterised in that：
The thickener ingredients include polyacrylamide, the isoparaffins of C13~14, the Pareths -6 of C9~11.
3. a kind of skin care whitening cream according to claim 1, it is characterised in that：2% is added in the vacuum emulsification pot
~6% emulsifier carries out co-emulsifier.
4. a kind of skin care whitening cream according to claim 1, it is characterised in that：The Chinese medical extract ingredient includes product
Felwort, adlay, the bletilla striata, oldenlandia diffusa, ginkgo leaf, Radix Angelicae Sinensis, radix ampelopsis, Korean ginseng, cordyceps extracting liquid, the extraction
The relative density of Chinese medical extract is 0.9-1.1.
5. a kind of skin care whitening cream according to claim 1, which is characterized in that contain according to every 100ml creams：Felwort
2%, adlay 1%, the bletilla striata 1%, oldenlandia diffusa 2%, ginkgo leaf 2%, Radix Angelicae Sinensis 1%, radix ampelopsis 1%, Korean ginseng 3%, cordyceps sinensis 3%, essence
0.03%, preservative 0.5~1.5%, thickener 0.5~1.5%, cream matrix 60%, surplus are deionized water.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810352652.XA CN108324650A (en) | 2018-04-19 | 2018-04-19 | A kind of ingredient and preparation method thereof of skin care whitening cream |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810352652.XA CN108324650A (en) | 2018-04-19 | 2018-04-19 | A kind of ingredient and preparation method thereof of skin care whitening cream |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108324650A true CN108324650A (en) | 2018-07-27 |
Family
ID=62934351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810352652.XA Pending CN108324650A (en) | 2018-04-19 | 2018-04-19 | A kind of ingredient and preparation method thereof of skin care whitening cream |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108324650A (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103251531A (en) * | 2013-04-28 | 2013-08-21 | 福建省梦娇兰日用化学品有限公司 | Relief propolis cream |
| CN103784368A (en) * | 2014-01-15 | 2014-05-14 | 广东雅丽洁精细化工有限公司 | Skin care composition and cream with relieving and whitening functions and preparation method thereof |
| CN104644507A (en) * | 2015-02-12 | 2015-05-27 | 安婕妤化妆品科技股份有限公司 | Nursing cream composition |
| CN105395467A (en) * | 2015-12-01 | 2016-03-16 | 山东皓尔生物工程有限公司 | Traditional Chinese medicinal composition, skin-care cosmetic and application of skin-care cosmetic |
| CN105541968A (en) * | 2016-01-27 | 2016-05-04 | 安婕妤化妆品科技股份有限公司 | Preparation method and application of pentapeptide |
| CN107789252A (en) * | 2017-10-31 | 2018-03-13 | 广州赛莱拉干细胞科技股份有限公司 | A kind of Skin whitening care cosmeticses |
-
2018
- 2018-04-19 CN CN201810352652.XA patent/CN108324650A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103251531A (en) * | 2013-04-28 | 2013-08-21 | 福建省梦娇兰日用化学品有限公司 | Relief propolis cream |
| CN103784368A (en) * | 2014-01-15 | 2014-05-14 | 广东雅丽洁精细化工有限公司 | Skin care composition and cream with relieving and whitening functions and preparation method thereof |
| CN104644507A (en) * | 2015-02-12 | 2015-05-27 | 安婕妤化妆品科技股份有限公司 | Nursing cream composition |
| CN105395467A (en) * | 2015-12-01 | 2016-03-16 | 山东皓尔生物工程有限公司 | Traditional Chinese medicinal composition, skin-care cosmetic and application of skin-care cosmetic |
| CN105541968A (en) * | 2016-01-27 | 2016-05-04 | 安婕妤化妆品科技股份有限公司 | Preparation method and application of pentapeptide |
| CN107789252A (en) * | 2017-10-31 | 2018-03-13 | 广州赛莱拉干细胞科技股份有限公司 | A kind of Skin whitening care cosmeticses |
Non-Patent Citations (1)
| Title |
|---|
| 宋丽雅，何聪芬: "《化妆品植物功效添加剂的研究与开发》", 30 September 2011, 中国轻工业出版社 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN110731922B (en) | Enhanced hair loss prevention and hair growth promoting composition | |
| CN106265348B (en) | Substrate with skin barrier repairing and anti-aging effects and preparation method and application thereof | |
| WO2021017846A1 (en) | Enhanced anti-aging cosmetic composition | |
| CN101732227B (en) | Composition for nourishing hair follicle, preventing hair drop and fixing hair and manufacturing method thereof | |
| JP2021020886A (en) | Anti-aging cosmetic composition | |
| CN108158931A (en) | A kind of moisturizing whitening cream of the extract containing Flos micheliae Albae and preparation method thereof | |
| CN105168054A (en) | Mask capable of supplementing water, whitening and removing wrinkles and preparation method of mask | |
| CN100558340C (en) | Cucurbitaceae oil is used to suppress the active application of 5 | |
| CN108524406A (en) | A kind of Golden flower facial mask and preparation method thereof | |
| CN109350579B (en) | Whitening cosmetic additive, whitening skin-refreshing lotion and preparation method thereof | |
| CN114632049A (en) | Hair loss prevention and hair growth composition | |
| CN109260116A (en) | It is a kind of containing plant extracts to peptide skin base solution and its production technology | |
| CN110731976A (en) | Hair loss preventing and hair growing composition | |
| CN108836901A (en) | A kind of facial mask essence of the Product filtrate containing saccharomycetes to make fermentation and preparation method thereof | |
| CN106176324A (en) | A kind of Whitening sunscreen cream containing Noni fruit quintessence oil and preparation method thereof | |
| CN101489528B (en) | Cell-activating agent, collagen production-promoting agent, bleaching agent, anti-oxidizing agent, anti-inflammatory agent, aromatase activity-promoting agent, protease activity-promoting agent, skin topical agent and food | |
| CN107536721B (en) | Composition for external skin preparation and use thereof | |
| CN111494286A (en) | Alopecia-stopping and hair-growing shampoo | |
| CN108324650A (en) | A kind of ingredient and preparation method thereof of skin care whitening cream | |
| CN105213270A (en) | Whitening spot-eliminating composition | |
| CN108514529A (en) | A kind of extracting method and application thereof of skin-lightening cosmetic Chinese medical extract | |
| CN112842952B (en) | Yeast fermented birch juice and application thereof in hair growth preventing composition | |
| CN108354891A (en) | One kind is releived creams and preparation method thereof | |
| CN108066189A (en) | There is the anti-ageing ganoderma lucidum skin care compositions for dispelling yellow and its application | |
| CN108078827A (en) | A kind of hair growth accelerating shampoo and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180727 |
|
| RJ01 | Rejection of invention patent application after publication |