CN108272687A - A kind of desalination wrinkle face mask of traditional Chinese medicine - Google Patents
A kind of desalination wrinkle face mask of traditional Chinese medicine Download PDFInfo
- Publication number
- CN108272687A CN108272687A CN201810282737.5A CN201810282737A CN108272687A CN 108272687 A CN108272687 A CN 108272687A CN 201810282737 A CN201810282737 A CN 201810282737A CN 108272687 A CN108272687 A CN 108272687A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- extract
- radix
- face mask
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/82—Preparation or application process involves sonication or ultrasonication
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
Abstract
The invention discloses a kind of desalination wrinkle face mask of traditional Chinese medicine, contain compound Chinese medicine ingredient in the face mask of traditional Chinese medicine；The compound Chinese medicine ingredient is prepared by following parts by weight raw material：12 20 parts of the fleece-flower root, 10 15 parts of Radix Notoginseng, 15 20 parts of ginkgo leaf, 10 15 parts of sophora flower, 9 14 parts of tealeaves, 6 10 parts of radix scrophulariae, 5 10 parts of campanulaceae；Synergy that the compound Chinese medicine ingredient has, good penetrability and the advantages that easily absorb, can quickly penetrate into and be absorbed by Skin Cell, promote the metabolism of Skin Cell, and Skin Cell is made to get well state, and moisture content of skin increases, wrinkle of skin desalination；The facial mask drug effect is gentle, and desalination wrinkle effect is good, and has no toxic side effect.
Description
Technical field
The present invention relates to cosmetic field, more particularly to a kind of face mask of traditional Chinese medicine with desalination wrinkle function.
Background technology
With the development of economy, improvement of living standard, people increasingly focus on the protection to skin.And facial mask is also shield
A primary and important skin care step in skin product.Facial mask was temporarily isolating using the of short duration time for being covered in face
Extraneous air and pollution, improves skin temperature, and the pore expansion of skin promotes sweat gland secretion and metabolism, makes skin
Oxygen content rises, and is conducive to a kind of product that skin excludes the product of epidermal cell metabolism and the oil substances of accumulation,
Moisture in facial mask penetrates into the cuticula of epidermis, and skin becomes soft, and skin is naturally bright flexible.
Medical research show the corrugated most basic reason of human skin be skin keep moisture ability with the growth at age and
Decline, most directly reaction is skin corrugation to the loss of moisture, and this point is especially apparent on the face people's.Current anti-wrinkle cosmetic
Product be based on this principle research and development, hot application, fumigating system from beauty parlor, facial mask all the fashion till now be from
The angle of moisturizing keeps the skin wet for facial skin, is allowed to restore elasticity, achievees the purpose that smooth away wrinkles, tender skin.With the age
Increase, skin fibroblasts and keratinocyte synthesis hyaluronic acid ability be gradually reduced, corium and epidermis hyalomitome
Acid concentration can all continuously decrease, and by Fick laws, the hyaluronic acid concentration of cutin layer surface also reduces, when skin surface hyalomitome
When acid is less than certain level, surface moisture can be caused to decrease.Numerous studies show that human skin surface's humidity is 15%-
30%, it makes one uncomfortable below or above this range, is less than this value for a long time, chapped skin, coarse, generation wrinkle will be made to lose
It is elastic, smooth and moist, coarse aging.Although there are more can desalinate wrinkle mask product, desalination wrinkle on market today
The effect of line is numerous.
Invention content
It is an object of the invention to overcome the shortcomings of that desalination wrinkle effect present in existing facial mask is poor, side effect is big, carry
For a kind of desalination wrinkle face mask of traditional Chinese medicine.The advantages that absorption synergistic, without side-effects and easy having is added in the facial mask
Compound Chinese medicine ingredient can increase moisture content of skin, restore skin elasticity and gloss, to make wrinkle desalinate or disappear, the present invention
Facial mask has excellent desalination wrinkle effect, and without side-effects.
In order to achieve the above-mentioned object of the invention, the present invention provides a kind of desalination wrinkle face mask of traditional Chinese medicine, which contains compound
Traditional Chinese medicine ingredients；The compound Chinese medicine ingredient is prepared by following parts by weight raw material：12-20 parts of the fleece-flower root, Radix Notoginseng 10-15
Part, 15-20 parts of ginkgo leaf, 10-15 parts of sophora flower, 9-14 parts of tealeaves, 6-10 parts of radix scrophulariae, 5-10 parts of campanulaceae.Raw materials meet
The relevant regulations of national cosmetic raw material.
Above-mentioned a kind of desalination wrinkle face mask of traditional Chinese medicine, it is preferred that the compound Chinese medicine ingredient is by the original of following weight
What material was prepared：15-18 parts of the fleece-flower root, 11-13 parts of Radix Notoginseng, 16-18 parts of ginkgo leaf, 11-14 parts of sophora flower, 10-13 parts of tealeaves,
7-9 parts of radix scrophulariae, 6-8 parts of campanulaceae；It is further preferred that the compound Chinese medicine ingredient be by following weight raw material prepare and
At：17 parts of the fleece-flower root, 12 parts of Radix Notoginseng, 17 parts of ginkgo leaf, 13 parts of sophora flower, 12 parts of tealeaves, 8 parts of radix scrophulariae, 7 parts of campanulaceae.By upper
Stating can preferably make the synergistic function of compound Chinese medicine ingredient maximum, desalinate wrinkle best results.
Above-mentioned a kind of desalination wrinkle face mask of traditional Chinese medicine, wherein the compound Chinese medicine ingredient is prepared by following preparation method
It obtains：
（1）Raw material disposal：After the fleece-flower root, radix scrophulariae and Radix Notoginseng are crushed respectively with papain and subtilopeptidase A into
Row hydrolysis process carries out separating-purifying to hydrolysate respectively and obtains radix-polygoni multiflori extract, the radix scrophulariae that molecular weight is less than 3000Da
Extract and Notogineng Extract；
Tealeaves is crushed, after sterilizing, carries out fermentation process with saccharomycete, Zygosaccharomyces rouxii and lactic acid bacteria, tunning is divided
The tea extract that molecular weight is less than 3000Da is obtained from purification；
After ginkgo leaf is crushed with 95% alcohol solution dipping, be used in combination ultrasonic wave to be handled, filtering collect filtrate, to filtrate
It carries out concentration purification and obtains ginkgo biloba p.e；
After sophora flower is crushed with 50% alcohol solution dipping, be used in combination ultrasonic wave to be handled, filtering collect filtrate, to filtrate into
Row concentration purification obtains Flos Sophorae extract；
After campanulaceae is crushed, after being impregnated with ethyl alcohol or water, separating-purifying soak obtains Radix Platycodonis extract；
（2）The preparation of compound Chinese medicine ingredient：By radix-polygoni multiflori extract, Flos Sophorae extract, ginkgo biloba p.e, Notogineng Extract,
Tea extract, Radix Scrophulariae extract and Radix Platycodonis extract in the ethanol solution of 50% volume ratio after mixing, with homogenizer into
Row homogenization, again purification obtain compound Chinese medicine ingredient.
Wherein, it is preferred that papain and subtilopeptidase A when the fleece-flower root, radix scrophulariae and Radix Notoginseng hydrolyze in step 1
Weight ratio be 1-3 ︰ 1-3；By preferred, protease can be quickly by the macromolecular egg in the fleece-flower root, radix scrophulariae and Radix Notoginseng
White matter is hydrolyzed to micromolecule polypeptide, it is easier to be absorbed by the skin, desalination wrinkle effect is more preferable.
Wherein, it is preferred that papain and subtilopeptidase A when the fleece-flower root, radix scrophulariae and Radix Notoginseng hydrolyze in step 1
Addition total amount be respectively the fleece-flower root, radix scrophulariae or Radix Notoginseng quality 0.001-0.01%；Additive amount is excessive, of high cost, and small molecule is more
Hydrolase polypeptide transition, desalination wrinkle effect reduce, and additive amount is too small, and high molecular weight protein hydrolysis is incomplete, hydrolysate small molecular
Content of peptides is low, and the desalination wrinkle effect of compound Chinese medicine ingredient reduces.
Wherein, it is preferred that the fleece-flower root, radix scrophulariae and the hydrolysis temperature of Radix Notoginseng are 20-30 DEG C, hydrolysis time 3-6h.
Wherein, it is preferred that saccharomycete, Zygosaccharomyces rouxii and the lactic acid bacteria weight ratio being inoculated with when tea leaf fermentation in step 1
For 2 ︰, 1 ︰ 2；By preferred, tea leaf fermentation product small molecular content of peptides higher, active ingredient be easier skin permeation and by
The absorption of skin, desalination wrinkle effect are more preferable.
Wherein, saccharomycete, Zygosaccharomyces rouxii and the inoculation of lactic acid bacteria total amount are tea quality when tea leaf fermentation in step 1
0.05-0.1%；Inoculum concentration is excessive, transition of fermenting, and protein is decomposed by transition in zymotic fluid, and desalination wrinkle effect is deteriorated；Inoculation
Measure too small, fermentation is incomplete, and zymotic fluid small molecular active constituent content is few, and desalination wrinkle effect equally reduces；Preferably, ferment
The inoculation total amount of female bacterium, Zygosaccharomyces rouxii and lactic acid bacteria is the 0.08% of tea quality.
Wherein, it is preferred that tea leaf fermentation temperature is 25-35 DEG C, fermentation time 10-24h.
Wherein, it is preferred that the frequency of ultrasonic wave is 60-80Hz in the processing procedure of ginkgo leaf in step 1；By preferred,
Active constituent content higher in ginkgo leaf filtrate, by-products content is less, and desalination wrinkle effect is more preferable.
Wherein, it is preferred that it is 70-85 DEG C that ginkgo leaf, which is ultrasonically treated temperature, processing time 0.5-2h；By preferred, silver
Active constituent content higher in apricot leaf filtrate, by-products content is less, and desalination wrinkle effect is more preferable.
Wherein, it is preferred that the frequency of ultrasonic wave is 30-50Hz in the processing procedure of sophora flower in step 1；By preferred, Chinese scholartree
Active constituent content higher in flower filtrate, by-products content is less, and desalination wrinkle effect is more preferable.
Wherein, it is preferred that it is 50-60 DEG C that sophora flower, which is ultrasonically treated temperature, processing time 0.5-2h；By preferred, sophora flower
Active constituent content higher in filtrate, by-products content is less, and desalination wrinkle effect is more preferable.
Wherein, the temperature of homogeneous is 75-80 DEG C in step 2, homogenization pressure 0.2-0.5Mpa；By homogeneous, energy will be each
Raw material extract is uniformly mixed, and macromolecular components therein are decomposed under the action of shearing force relatively small molecular weight at
Point, it is easier to it permeates and is absorbed by the skin, simultaneously, moreover it is possible to the allergic component in extract be inactivated, side effect is reduced and occur generally
Rate.
A kind of desalination wrinkle face mask of traditional Chinese medicine, wherein the compound Chinese medicine ingredient contained is targetedly to use Different Extraction Method
From a variety of natural materials extract needed for active constituent be combined, using the fleece-flower root and Radix Notoginseng as monarch drug in a prescription, ginkgo leaf, sophora flower and
Tealeaves is ministerial drug, and radix scrophulariae is adjutant, and campanulaceae is to make medicine, is made using the synergy between different activities ingredient in each raw material
With, it can quickly penetrate into and be absorbed by Skin Cell, promote the metabolism of Skin Cell, Skin Cell is made to get well state,
Moisture content of skin increases, wrinkle of skin desalination；Facial mask desalination wrinkle effect is good, and drug effect is gentle, and has no toxic side effect.
Above-mentioned a kind of desalination wrinkle face mask of traditional Chinese medicine, wherein the desalination wrinkle face mask of traditional Chinese medicine is in conventional facial mask system
Add what above-mentioned compound Chinese medicine ingredient was prepared during standby；Preferably, the compound Chinese medicine ingredient weight added in the facial mask
Amount percentage is 0.5-5%；Most preferably, the compound Chinese medicine composition by weight percent of addition is 1-2%.
Compared with prior art, beneficial effects of the present invention：
1, the compound Chinese medicine ingredient contained in facial mask of the present invention is by the synergistic function of different active constituent in each raw material,
It can quickly penetrate into and be absorbed by Skin Cell, promote the metabolism of Skin Cell, so that Skin Cell is got well state, skin
Water content increases, wrinkle of skin desalination.
2, processing of the compound Chinese medicine ingredient contained in facial mask of the present invention Jing Guo different process method, containing small point more
Sub- active material, it is more preferable to the permeability of skin, it is easier to be absorbed by the skin, desalination wrinkle effect is more preferable.
3, the compound Chinese medicine ingredient contained in facial mask of the present invention by homogenization by the easy allergy object in raw extract
Matter is inactivated, and anaphylaxis and chance of side effect are reduced, and improves the adaptability of facial mask.
Specific implementation mode
With reference to test example and specific implementation mode, the present invention is described in further detail.But this should not be understood
It is only limitted to embodiment below for the range of the above-mentioned theme of the present invention, it is all that this is belonged to based on the technology that the content of present invention is realized
The range of invention.
Embodiment 1
A kind of desalination wrinkle face mask of traditional Chinese medicine, the compound Chinese medicine ingredient for being 2% containing weight percent；
The compound Chinese medicine ingredient is prepared by following parts by weight raw material：17 parts of the fleece-flower root, 12 parts of Radix Notoginseng, 17 parts of ginkgo leaf,
13 parts of sophora flower, 12 parts of tealeaves, 8 parts of radix scrophulariae, 7 parts of campanulaceae；
Above-mentioned raw material are prepared the compound Chinese medicine ingredient by following preparation method：
（1）Raw material disposal：With 0.005% that total amount is fleece-flower root amount, the wood that weight ratio is 1 ︰ 1 after the fleece-flower root is crushed
Melon protease and subtilopeptidase A hydrolyze 4h at a temperature of 25 DEG C, and carrying out separating-purifying to hydrolysate obtains molecular weight
Radix-polygoni multiflori extract less than 3000Da；
With 0.005% that total amount is Radix Notoginseng amount, the papain that weight ratio is 1 ︰ 1 and hay bacillus after radix scrophulariae is crushed
Protease hydrolyzes 4h at a temperature of 25 DEG C, and obtaining radix scrophulariae of the molecular weight less than 3000Da to hydrolysate progress separating-purifying carries
Take object；
With 0.005% that total amount is Radix Notoginseng amount, the papain that weight ratio is 1 ︰ 1 and hay bacillus after Radix Notoginseng is crushed
Protease hydrolyzes 4h at a temperature of 25 DEG C, and obtaining Radix Notoginseng of the molecular weight less than 3000Da to hydrolysate progress separating-purifying carries
Take object；
Tealeaves is crushed, after sterilizing, inoculation total amount is the 0.08% of tea quality, weight ratio is the saccharomycete of 2 ︰, 1 ︰ 2, Shandong
Family name Mucor and lactic acid bacteria, ferment 18h at a temperature of 30 DEG C, and obtaining molecular weight to tunning progress separating-purifying is less than
The tea extract of 3000Da；
After ginkgo leaf is crushed, 95% ethanol solution is added, the ultrasonic wave that frequency is 70Hz is used in combination to be handled at a temperature of 78 DEG C
Filtrate is collected in 1h, filtering, and carrying out concentration purification to filtrate obtains ginkgo biloba p.e；
After sophora flower is crushed, 50% ethanol solution is added, the ultrasonic wave that frequency is 40Hz is used in combination to be handled at a temperature of 55 DEG C
Filtrate is collected in 1h, filtering, and carrying out concentration purification to filtrate obtains Flos Sophorae extract；
After campanulaceae is crushed, after being impregnated with ethyl alcohol or water, separating-purifying soak obtains Radix Platycodonis extract；
（2）The preparation of compound Chinese medicine ingredient：By radix-polygoni multiflori extract, Flos Sophorae extract, tea extract, ginkgo biloba p.e,
Notogineng Extract, Radix Scrophulariae extract and Radix Platycodonis extract in the ethanol solution of 50% volume ratio after mixing, in 78 DEG C of temperature
It spends, carry out homogenization under the pressure of 0.4Mpa, purification again obtains compound Chinese medicine ingredient.
Embodiment 2
A kind of desalination wrinkle face mask of traditional Chinese medicine, the compound Chinese medicine ingredient for being 2% containing weight percent；
The compound Chinese medicine ingredient is prepared by following parts by weight raw material：12 parts of the fleece-flower root, 15 parts of Radix Notoginseng, 20 parts of ginkgo leaf,
10 parts of sophora flower, 14 parts of tealeaves, 6 parts of radix scrophulariae, 5 parts of campanulaceae；
Above-mentioned raw material are prepared the compound Chinese medicine ingredient by following preparation method：
（1）Raw material disposal：With 0.001% that total amount is fleece-flower root amount, the wood that weight ratio is 3 ︰ 1 after the fleece-flower root is crushed
Melon protease and subtilopeptidase A hydrolyze 6h at a temperature of 20 DEG C, and carrying out separating-purifying to hydrolysate obtains molecular weight
Radix-polygoni multiflori extract less than 3000Da；
The papain and hay bacillus egg for being 1 ︰ 3 with total amount is Radix Notoginseng amount 0.01%, weight ratio after radix scrophulariae is crushed
White enzyme hydrolyzes 3h at a temperature of 30 DEG C, and carrying out separating-purifying to hydrolysate obtains radix scrophulariae extraction of the molecular weight less than 3000Da
Object；
The papain and hay bacillus egg for being 1 ︰ 3 with total amount is Radix Notoginseng amount 0.01%, weight ratio after Radix Notoginseng is crushed
White enzyme hydrolyzes 3h at a temperature of 30 DEG C, and carrying out separating-purifying to hydrolysate obtains Radix Notoginseng extraction of the molecular weight less than 3000Da
Object；
By tealeaves crush, sterilizing after, inoculation total amount be the 0.1% of tea quality, saccharomycete, the Lu Shi that weight ratio is 2 ︰, 1 ︰ 2
Mucor and lactic acid bacteria, ferment 10h at a temperature of 35 DEG C, and carrying out separating-purifying to tunning obtains molecular weight less than 3000Da
Tea extract；
After ginkgo leaf is crushed, 95% ethanol solution is added, the ultrasonic wave that frequency is 80Hz is used in combination to be handled at a temperature of 70 DEG C
Filtrate is collected in 0.5h, filtering, and carrying out concentration purification to filtrate obtains ginkgo biloba p.e；
After sophora flower is crushed, 50% ethanol solution is added, the ultrasonic wave that frequency is 30Hz is used in combination to be handled at a temperature of 50 DEG C
Filtrate is collected in 2h, filtering, and carrying out concentration purification to filtrate obtains Flos Sophorae extract；
After campanulaceae is crushed, after being impregnated with ethyl alcohol or water, separating-purifying soak obtains Radix Platycodonis extract；
（2）The preparation of compound Chinese medicine ingredient：By radix-polygoni multiflori extract, Flos Sophorae extract, tea extract, ginkgo biloba p.e,
Notogineng Extract, Radix Scrophulariae extract and Radix Platycodonis extract in the ethanol solution of 50% volume ratio after mixing, in 80 DEG C of temperature
It spends, carry out homogenization under the pressure of 0.2Mpa, purification again obtains compound Chinese medicine ingredient.
Embodiment 3
A kind of desalination wrinkle face mask of traditional Chinese medicine, the compound Chinese medicine ingredient for being 2% containing weight percent；
The compound Chinese medicine ingredient is prepared by following parts by weight raw material：20 parts of the fleece-flower root, 10 parts of Radix Notoginseng, 15 parts of ginkgo leaf,
10 parts of sophora flower, 9 parts of tealeaves, 10 parts of radix scrophulariae, 10 parts of campanulaceae；
Above-mentioned raw material are prepared the compound Chinese medicine ingredient by following preparation method：
（1）Raw material disposal：With 0.01% that total amount is fleece-flower root amount, the pawpaw that weight ratio is 3 ︰ 1 after the fleece-flower root is crushed
Protease and subtilopeptidase A hydrolyze 3h at a temperature of 30 DEG C, and it is small to obtain molecular weight to hydrolysate progress separating-purifying
In the radix-polygoni multiflori extract of 3000Da；
With 0.001% that total amount is Radix Notoginseng amount, the papain that weight ratio is 1 ︰ 3 and hay bacillus after radix scrophulariae is crushed
Protease hydrolyzes 6h at a temperature of 20 DEG C, and obtaining radix scrophulariae of the molecular weight less than 3000Da to hydrolysate progress separating-purifying carries
Take object；
With 0.001% that total amount is Radix Notoginseng amount, the papain that weight ratio is 1 ︰ 3 and hay bacillus after Radix Notoginseng is crushed
Protease hydrolyzes 6h at a temperature of 20 DEG C, and obtaining Radix Notoginseng of the molecular weight less than 3000Da to hydrolysate progress separating-purifying carries
Take object；
Tealeaves is crushed, after sterilizing, inoculation total amount is the 0.05% of tea quality, weight ratio is the saccharomycete of 2 ︰, 1 ︰ 2, Shandong
Family name Mucor and lactic acid bacteria, ferment for 24 hours at a temperature of 25 DEG C, and obtaining molecular weight to tunning progress separating-purifying is less than
The tea extract of 3000Da；
After ginkgo leaf is crushed, 95% ethanol solution is added, the ultrasonic wave that frequency is 60Hz is used in combination to be handled at a temperature of 85 DEG C
Filtrate is collected in 2h, filtering, and carrying out concentration purification to filtrate obtains ginkgo biloba p.e；
After sophora flower is crushed, 50% ethanol solution is added, the ultrasonic wave that frequency is 50Hz is used in combination to be handled at a temperature of 60 DEG C
Filtrate is collected in 0.5h, filtering, and carrying out concentration purification to filtrate obtains Flos Sophorae extract；
After campanulaceae is crushed, after being impregnated with ethyl alcohol or water, separating-purifying soak obtains Radix Platycodonis extract；
（2）The preparation of compound Chinese medicine ingredient：By radix-polygoni multiflori extract, Flos Sophorae extract, tea extract, ginkgo biloba p.e,
Notogineng Extract, Radix Scrophulariae extract and Radix Platycodonis extract in the ethanol solution of 50% volume ratio after mixing, in 75 DEG C of temperature
It spends, carry out homogenization under the pressure of 0.5Mpa, purification again obtains compound Chinese medicine ingredient.
Comparative example 1
A kind of desalination wrinkle face mask of traditional Chinese medicine, the compound Chinese medicine ingredient for being 2% containing weight percent；
The compound Chinese medicine ingredient is prepared by following parts by weight raw material：17 parts of the fleece-flower root, 17 parts of ginkgo leaf, 13 parts of sophora flower,
12 parts of tealeaves, 8 parts of radix scrophulariae, 7 parts of campanulaceae；
The compound Chinese medicine ingredient is that above-mentioned raw material are prepared according to the preparation method of embodiment 1.
Comparative example 2
A kind of desalination wrinkle face mask of traditional Chinese medicine, the compound Chinese medicine ingredient for being 2% containing weight percent；
The compound Chinese medicine ingredient is that Radix Notoginseng is prepared according to the preparation method of the compound Chinese medicine ingredient in embodiment 1.
Comparative example 3
A kind of desalination wrinkle face mask of traditional Chinese medicine, the compound Chinese medicine ingredient for being 2% containing weight percent；
The compound Chinese medicine ingredient is prepared by following parts by weight raw material：10 parts of the fleece-flower root, 5 parts of Radix Notoginseng, 17 parts of ginkgo leaf, Chinese scholartree
Spend 13 parts, 20 parts of tealeaves, 15 parts of radix scrophulariae, 7 parts of campanulaceae；
The compound Chinese medicine ingredient is that above-mentioned raw material are prepared according to the preparation method of embodiment 1.
Comparative example 4
A kind of desalination wrinkle face mask of traditional Chinese medicine, the compound Chinese medicine ingredient for being 2% containing weight percent；
The compound Chinese medicine ingredient raw material are same as Example 1；
Above-mentioned raw material are prepared the compound Chinese medicine ingredient by following preparation method：
（1）Raw material disposal：After the fleece-flower root, sophora flower, tealeaves, ginkgo leaf, Radix Notoginseng, campanulaceae and tealeaves are crushed respectively, ethyl alcohol is used
Or after water is impregnated, separating-purifying soak obtains radix-polygoni multiflori extract, Flos Sophorae extract, tea extract, ginkgo leaf and carries
Take object, Notogineng Extract, Radix Platycodonis extract and Radix Scrophulariae extract；
（2）The preparation of compound Chinese medicine ingredient：By radix-polygoni multiflori extract, Flos Sophorae extract, tea extract, ginkgo biloba p.e,
Notogineng Extract, Radix Scrophulariae extract and Radix Platycodonis extract in the ethanol solution of 50% volume ratio after mixing, in 78 DEG C of temperature
It spends, carry out homogenization under the pressure of 0.4Mpa, purification again obtains compound Chinese medicine ingredient.
Comparative example 5
A kind of desalination wrinkle face mask of traditional Chinese medicine, the compound Chinese medicine ingredient for being 2% containing weight percent；
The compound Chinese medicine ingredient raw material are same as Example 1；
Above-mentioned raw material are prepared the compound Chinese medicine ingredient by following preparation method：
（1）Raw material disposal：It is handled according to the method for embodiment 1；
（2）The preparation of compound Chinese medicine ingredient：By radix-polygoni multiflori extract, Flos Sophorae extract, tea extract, ginkgo biloba p.e,
Notogineng Extract, Radix Scrophulariae extract and Radix Platycodonis extract after mixing, purify again in the ethanol solution of 50% volume ratio
To compound Chinese medicine ingredient.
Comparative example 6
A kind of desalination wrinkle face mask of traditional Chinese medicine, the compound Chinese medicine ingredient for being 2% containing weight percent；
The compound Chinese medicine ingredient raw material are same as Example 1；
Above-mentioned raw material are prepared the compound Chinese medicine ingredient by following preparation method：
（1）Raw material disposal：With 0.005% that total amount is fleece-flower root amount, the wood that weight ratio is 1 ︰ 1 after the fleece-flower root is crushed
Melon protease and subtilopeptidase A hydrolyze 4h at a temperature of 25 DEG C, and carrying out separating-purifying to hydrolysate obtains molecular weight
Radix-polygoni multiflori extract less than 3000Da；
With 0.005% that total amount is Radix Notoginseng amount, the papain that weight ratio is 1 ︰ 1 and hay bacillus after radix scrophulariae is crushed
Protease hydrolyzes 4h at a temperature of 25 DEG C, and obtaining radix scrophulariae of the molecular weight less than 3000Da to hydrolysate progress separating-purifying carries
Take object；
With 0.005% that total amount is Radix Notoginseng amount, the papain that weight ratio is 1 ︰ 1 and hay bacillus after Radix Notoginseng is crushed
Protease hydrolyzes 4h at a temperature of 25 DEG C, and obtaining Radix Notoginseng of the molecular weight less than 3000Da to hydrolysate progress separating-purifying carries
Take object；
By tealeaves crush, sterilizing after, inoculation total amount be the 0.08% of tea quality, the saccharomycete and lactic acid that weight ratio is 1 ︰ 1
Bacterium, ferment 18h at a temperature of 30 DEG C, and carrying out separating-purifying to tunning obtains radix scrophulariae extraction of the molecular weight less than 3000Da
Object；
After ginkgo leaf is crushed, 95% ethanol solution is added, the ultrasonic wave that frequency is 70Hz is used in combination to be handled at a temperature of 78 DEG C
Filtrate is collected in 1h, filtering, and carrying out concentration purification to filtrate obtains ginkgo biloba p.e；
After sophora flower is crushed, 50% ethanol solution is added, the ultrasonic wave that frequency is 60Hz is used in combination to be handled at a temperature of 55 DEG C
Filtrate is collected in 1h, filtering, and carrying out concentration purification to filtrate obtains Flos Sophorae extract；
After campanulaceae is crushed, after being impregnated with ethyl alcohol or water, separating-purifying soak obtains Radix Platycodonis extract；
（2）The preparation of compound Chinese medicine ingredient：By radix-polygoni multiflori extract, Flos Sophorae extract, tea extract, ginkgo biloba p.e,
Notogineng Extract, Radix Scrophulariae extract and Radix Platycodonis extract in the ethanol solution of 50% volume ratio after mixing, in 78 DEG C of temperature
It spends, carry out homogenization under the pressure of 0.4Mpa, purification again obtains compound Chinese medicine ingredient.
The desalination wrinkle face mask of traditional Chinese medicine that above-described embodiment 1-3 and comparative example 1-6 are prepared is tried out, is randomly choosed
200 volunteers（Each half of men and women, the age is between 40-50 Sui）, be divided into 10 groups, wherein 1-9 try out respectively embodiment 1-3 and
The facial mask that comparative example 1-6 is prepared, the best desalination wrinkle face mask of traditional Chinese medicine of the 10th group of selection commercial type, uses 60 days
Afterwards, skin is detected and is compared, obtain following data：
| Test group | Allergy number | Skin elasticity | Wrinkle is reduced（%） | Skin gloss | Water content（%） |
| 1（Embodiment 1） | 0 | ++++ | 22.6 | ++++ | 25.2 |
| 2（Embodiment 2） | 0 | ++++ | 21.8 | ++++ | 24.6 |
| 3（Embodiment 3） | 0 | ++++ | 21.5 | ++++ | 25.0 |
| 4（Comparative example 1） | 0 | ++ | 12.7 | ++ | 21.6 |
| 5（Comparative example 2） | 0 | + | 3.6 | + | 20.5 |
| 6（Comparative example 3） | 0 | +++ | 18.7 | +++ | 24.3 |
| 7（Comparative example 4） | 0 | ++ | 16.8 | ++ | 19.7 |
| 8（Comparative example 5） | 1 | +++ | 18.6 | +++ | 21.2 |
| 9（Comparative example 6） | 0 | +++ | 20.5 | +++ | 24.5 |
| 10（Commercially available facial mask） | 0 | +++ | 19.8 | +++ | 23.4 |
Note："+" is more, then skin condition indicates better.
By the above proof test data it is found that the facial mask that the on probation embodiment 1-3 of 1-3 groups is prepared, in facial mask
Compound Chinese medicine ingredient is readily permeable and is absorbed by the skin, and desalinates wrinkle significant effect, without side-effects；4th group is in comparative example 1
The facial mask being prepared lacks Radix Notoginseng in raw material, and compound Chinese medicine ingredient loses synergistic function, to the desalination wrinkle of skin
Significant effect reduces；5th group is the facial mask being prepared in comparative example 3, only used Radix Notoginseng as raw material, obtained facial mask
Desalinate wrinkle poor effect, and comparative example 1 is combined with comparative example 2, it is known that between each ingredient of compound Chinese medicine ingredient of the present invention
With synergistic function；6th group is the facial mask being prepared in comparative example 3, is adjusted to raw material usage, not in this hair
In bright range, compatibility in compound Chinese medicine ingredient is caused to change, synergistic function disappears, and the desalination wrinkle effect of facial mask is aobvious
Writing reduces；The 7th group of facial mask obtained for preparation method in comparative example 4, the 8th group of facial mask obtained for preparation method in comparative example 5,
In the preparation process of compound Chinese medicine ingredient, method not using the present invention, active ingredient molecular weight is larger, and small component is effective
Ingredient is less, is unfavorable for the infiltration and absorption of skin, and desalination wrinkle significant effect reduces；9th group is preparation method in comparative example 6
The facial mask being prepared, in the preparation process of compound Chinese medicine ingredient, the extracting parameters of bulk pharmaceutical chemicals be not it is given to this invention,
The desalination wrinkle effect for extracting obtained compound Chinese medicine ingredient is caused to reduce, the desalination wrinkle effect of facial mask reduces.
Claims (10)
1. a kind of desalination wrinkle face mask of traditional Chinese medicine, which is characterized in that contain compound Chinese medicine ingredient；The compound Chinese medicine ingredient is by following
Parts by weight raw material are prepared：12-20 parts of the fleece-flower root, 10-15 parts of Radix Notoginseng, 15-20 parts of ginkgo leaf, 10-15 parts of sophora flower, tealeaves
9-14 parts, 6-10 parts of radix scrophulariae, 5-10 parts of campanulaceae；
The compound Chinese medicine ingredient is prepared by following preparation method：
（1）Raw material disposal：After the fleece-flower root, radix scrophulariae and Radix Notoginseng are crushed respectively with papain and subtilopeptidase A into
Row hydrolysis process carries out separating-purifying to hydrolysate respectively and obtains radix-polygoni multiflori extract, the radix scrophulariae that molecular weight is less than 3000Da
Extract and Notogineng Extract；
Tealeaves is crushed, after sterilizing, carries out fermentation process with saccharomycete, Zygosaccharomyces rouxii and lactic acid bacteria, tunning is divided
The tea extract that molecular weight is less than 3000Da is obtained from purification；
After ginkgo leaf is crushed with 95% alcohol solution dipping, be used in combination ultrasonic wave to be handled, filtering collect filtrate, to filtrate
It carries out concentration purification and obtains ginkgo biloba p.e；
After sophora flower is crushed with 50% alcohol solution dipping, be used in combination ultrasonic wave to be handled, filtering collect filtrate, to filtrate into
Row concentration purification obtains Flos Sophorae extract；
After campanulaceae is crushed, after being impregnated with ethyl alcohol or water, separating-purifying soak obtains Radix Platycodonis extract；
（2）The preparation of compound Chinese medicine ingredient：By radix-polygoni multiflori extract, Flos Sophorae extract, ginkgo biloba p.e, Notogineng Extract,
Tea extract, Radix Scrophulariae extract and Radix Platycodonis extract in the ethanol solution of 50% volume ratio after mixing, with homogenizer into
Row homogenization, again purification obtain compound Chinese medicine ingredient.
2. face mask of traditional Chinese medicine according to claim 1, which is characterized in that the compound Chinese medicine ingredient is by following parts by weight raw material
It is prepared：15-18 parts of the fleece-flower root, 11-13 parts of Radix Notoginseng, 16-18 parts of ginkgo leaf, 11-14 parts of sophora flower, 10-13 parts of tealeaves, radix scrophulariae
7-9 parts, 6-8 parts of campanulaceae.
3. face mask of traditional Chinese medicine according to claim 2, which is characterized in that the compound Chinese medicine ingredient is by following weight
Raw material be prepared：17 parts of the fleece-flower root, 12 parts of Radix Notoginseng, 17 parts of ginkgo leaf, 13 parts of sophora flower, 12 parts of tealeaves, 8 parts of radix scrophulariae, tangerine
7 parts of stalk.
4. face mask of traditional Chinese medicine according to claim 1, which is characterized in that step（1）When the middle fleece-flower root, radix scrophulariae and Radix Notoginseng hydrolyze,
The papain of addition and the weight ratio of subtilopeptidase A are 1-3 ︰ 1-3.
5. face mask of traditional Chinese medicine according to claim 1, which is characterized in that step（1）When middle tea leaf fermentation, the saccharomycete of inoculation,
Zygosaccharomyces rouxii and lactic acid bacteria weight ratio are 2 ︰, 1 ︰ 2.
6. face mask of traditional Chinese medicine according to claim 1, which is characterized in that step（1）Ultrasonic wave in the processing procedure of middle ginkgo leaf
Frequency be 60-80Hz.
7. face mask of traditional Chinese medicine according to claim 1, which is characterized in that step（1）It is 70-85 that middle ginkgo leaf, which is ultrasonically treated temperature,
DEG C, processing time 0.5-2h.
8. face mask of traditional Chinese medicine according to claim 1, which is characterized in that step（1）Ultrasonic wave in the processing procedure of middle sophora flower
Frequency is 30-50Hz.
9. face mask of traditional Chinese medicine according to claim 1, which is characterized in that step（1）It is 50-60 that middle sophora flower, which is ultrasonically treated temperature,
DEG C, processing time 0.5-2h.
10. face mask of traditional Chinese medicine according to claim 1, which is characterized in that step（2）The temperature of middle homogeneous is 75-80 DEG C, homogeneous
Pressure is 0.2-0.5Mpa.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810282737.5A CN108272687A (en) | 2018-04-02 | 2018-04-02 | A kind of desalination wrinkle face mask of traditional Chinese medicine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810282737.5A CN108272687A (en) | 2018-04-02 | 2018-04-02 | A kind of desalination wrinkle face mask of traditional Chinese medicine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108272687A true CN108272687A (en) | 2018-07-13 |
Family
ID=62810837
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810282737.5A Withdrawn CN108272687A (en) | 2018-04-02 | 2018-04-02 | A kind of desalination wrinkle face mask of traditional Chinese medicine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108272687A (en) |
-
2018
- 2018-04-02 CN CN201810282737.5A patent/CN108272687A/en not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104546532B (en) | Essence containing chitosan oligomer and jellyfish collagen albumen and its facial mask being made | |
| CN108653035B (en) | Whitening and moisturizing small-molecule peptide mask and preparation method thereof | |
| CN110592151B (en) | Fermentation liquor with high content of gamma-aminobutyric acid produced by lactic acid bacteria and application of fermentation liquor in cosmetics | |
| CN111534455B (en) | Preparation of lactobacillus sporolysis product and application of lactobacillus sporolysis product in cosmetics | |
| CN107802543B (en) | Roxburgh rose element skin-refreshing biological fiber mask and preparation method thereof | |
| CN111643389A (en) | Anti-wrinkle whitening repair mask containing marine bioactive peptide and preparation method thereof | |
| CN114557927B (en) | Yeast essence water composition, yeast essence water, and preparation method and application thereof | |
| CN107233295A (en) | A kind of sponge gourd enzyme liquid acted on skin whitening, moisturizing and its mask product | |
| CN108309851A (en) | A kind of face cream with anti-senescence function | |
| CN108324665A (en) | A kind of face mask of traditional Chinese medicine with pore refining function | |
| CN113663051A (en) | Composition of skipjack elastin peptide and collagen oligopeptide and preparation method thereof | |
| CN111329784A (en) | Wrinkle-removing essence cream and preparation method thereof | |
| CN108324602A (en) | A kind of face cream that can increase resisting skin allergy | |
| CN108324613A (en) | A kind of face cream and preparation method thereof of desalination wrinkle | |
| CN114469817B (en) | Pore-shrinking composition and preparation method and application thereof | |
| CN108272687A (en) | A kind of desalination wrinkle face mask of traditional Chinese medicine | |
| CN108338960A (en) | A kind of tender skin face mask of traditional Chinese medicine | |
| CN107536780A (en) | A kind of removing acne and eliminating mark shin moisturizer and preparation method thereof | |
| CN108451811A (en) | A kind of delay aging drug facial mask | |
| KR20010090063A (en) | Mud omitted | |
| CN108451849A (en) | A kind of face mask of traditional Chinese medicine of prevention dark sore | |
| CN108324640A (en) | One kind lightening the stain face mask of traditional Chinese medicine | |
| CN111568799A (en) | Application of holothurian glycolysis element in whitening products | |
| CN111714399A (en) | Whitening, antibacterial and cutin-removing hand sanitizer and preparation method thereof | |
| CN108403581A (en) | A kind of face cream and preparation method thereof lightened the stain |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20180713 |
|
| WW01 | Invention patent application withdrawn after publication |