CN108248029A - A kind of special ultrasonic 3D printing equipment of artificial trachea and complex machining process - Google Patents

A kind of special ultrasonic 3D printing equipment of artificial trachea and complex machining process Download PDF

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Publication number
CN108248029A
CN108248029A CN201810208935.7A CN201810208935A CN108248029A CN 108248029 A CN108248029 A CN 108248029A CN 201810208935 A CN201810208935 A CN 201810208935A CN 108248029 A CN108248029 A CN 108248029A
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CN
China
Prior art keywords
artificial trachea
artificial
printing
printer
trachea
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810208935.7A
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Chinese (zh)
Inventor
张国智
赵婷
高鑫洋
刘常辉
刘嘉鑫
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Xinxiang University
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Xinxiang University
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Publication date
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Priority to CN201810208935.7A priority Critical patent/CN108248029A/en
Publication of CN108248029A publication Critical patent/CN108248029A/en
Pending legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00Processes of additive manufacturing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y30/00Apparatus for additive manufacturing; Details thereof or accessories therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y70/00Materials specially adapted for additive manufacturing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29LINDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00Other particular articles
    • B29L2031/753Medical equipment; Accessories therefor
    • B29L2031/7532Artificial members, protheses

Abstract

The invention discloses a kind of special ultrasonic 3D printing equipment of artificial trachea and combined machining methods, belong to man-made organ manufacture field.The present invention is improved 3D printer, printer includes print head, feeding roller, guide rail, design 3 print heads, print three layers of artificial trachea respectively simultaneously, inner layer material is collagen, intermediate layer material is carbon fiber, and cladding material is silica gel, promotes the combination of three interlayers and the formation of the bionical micro-structure of internal layer surface by ultrasonic vibration.Ultrasound and compound prepare of 3D printing are processed artificial trachea by the present invention, and the artificial organ mass of gained is light, and intensity is good, good toughness, and good biocompatibility is not likely to produce biocompatible.Application prospect is had a vast market in related fields such as manufacture of intraocular tracheaes.

Description

A kind of special ultrasonic 3D printing equipment of artificial trachea and complex machining process
Technical field
The present invention relates to a kind of special ultrasonic 3D printing equipment of artificial trachea and combined machining methods, belong to man-made organ and add Work field.
Background technology
Tracheae because tumour, physics and chemistry when factors cause it is narrow influence tracheae function due to have to trachea resection rebuild.When excision is grown For degree more than 6cm, then previous anastomotic tension is high, easily generates the severe complications such as anastomotic leakage.At this moment it needs to borrow the generations such as artificial trachea Articles for use rebuild tracheae.Since nineteen forty-six, some external scholars have been devoted to the zoopery of artificial trachea, but study hair There is local infection, previous anastomotics after existing above-mentioned artificial trachea implantation to split, the multiple complications such as granulation formation, trachea displacement, So as to limit the clinical practice of artificial trachea.To solve these problems, more preferably artificial trachea, domestic and foreign scholars are sought It does a lot of work.It with the development of 3D technology, not only played an important role in manufacturing field, and led in biological medicine Domain is widely used, such as:The success obtained clinically based on 3D printing technique manufacture of intraocular blood vessel in recent years should With, it can be seen that, 3D printing technique has broad application prospects in the manufacture of artificial trachea.However, artificial trachea into Material gain carries out clinical application with 3D printing technique, it is necessary to solve the problems, such as three aspects:First, biocompatible phenomenon is not generated; Second, the mechanical property with person's windpipe is needed to match and has good mechanical property;Third can complete the special of 3D printing Biomaterial.As can be seen that using 3D printing technique manufacture, convenient for the artificial trachea of application, in addition to the materials, 3D is beaten Print machine equipment and corresponding 3D printing technique are to improve the quality assurance of artificial trachea mechanical property.
Invention content
To ensure artificial trachea quality, improve and control its mechanical property, the present invention propose it is a kind of it is rational in infrastructure, suitable for facing The artificial tracheae 3D printing equipment that bed promotes and applies;Another object is to provide its 3D printing technique.
Purpose to realize the present invention is improved 3D printer, and 3 printings are set in the 3D printer of artificial trachea Head, while printing artificial trachea internal layer, artificial trachea middle layer, artificial trachea outer layer, the material of artificial trachea internal layer are respectively Collagen, the material of artificial trachea middle layer is carbon fibre material, and the material of artificial trachea outer layer is silica gel, also, beating During print, workbench planar can carry out ultrasound conjunction vibration by any direction, promote three layers of combination, print similar biology The surface texture of structure.
Specific technical solution is as follows:
Artificial tracheae 3D printing equipment of the present invention is made of electronic section, printer and software, printer include print head, Feeding roller, guide rail, which is characterized in that X, Y, Z three-dimensional guide rail are set on printer body, and Y guide rail is along Y-direction and body It is connected, X guide rails connect Y guide rail by sliding block, and Z guide rails connect X guide rails by sliding block;X, Y, Z-direction guide rail are respectively along respective side It is arranged to being arranged in order into three.
Three print heads of printer setup, three print heads are separately fixed at by sliding block on three Z guide rails, along Z-direction Movement.
Each print head connects respective feeding roller by conveying pipeline, and feeding roller is fixed on printing body.
Printer organism bottom is equipped with excusing from death wave working plate, and excusing from death wave working plate is by active operation platen, Liang Tai Or more ultrasonic vibration installation compositions, ultrasonic vibration installation is fixed on active operation platen by upper and lower pressing plate and screw, Also, it has arc groove in direction in length and breadth in active operation platen upper edge pallet, the installation position of ultrasonic vibration installation is adjusted It puts, thus, ultrasonic movable table can carry out the conjunction ultrasonic vibration of horizontal any direction.
Manufacture of intraocular tracheae technical process of the present invention is as follows:
Step 1 establishes the three-dimensional digital printer model of artificial trachea:It is calculated according to mechanical property and experiment test, it is and right Than the mechanical property of popularity pipe, material composition, three layers of structure, concrete shape and size according to artificial trachea, design is artificial The thickness ratio of three interlayer of tracheae.
Step 2 prepares three kinds of 3D printing materials of collagen, carbon fiber, silica gel for 3D printing.
Step 3 adjusts the installation site of two ultrasonic vibration installations of ultrasonic movable table and fixes, adjusts it Oscillation Amplitude and vibration frequency, preferably vibration amplitude are 0.1-0.2 millimeters, vibration frequency 20-25kHz.
The three-dimensional digitalization model of artificial trachea is imported printer apparatus, printing flow is set, using needle by step 4 Diameter print head of different sizes is printed.It is preferred that the outer layer of 0.3 millimeter of printhead prints artificial trachea, with 0.2 milli The middle layer of the printhead prints artificial trachea of rice, with the internal layer of 0.1 millimeter of printhead prints artificial trachea.Inner layer material is Collagen, intermediate layer material are carbon fiber, and cladding material is silica gel.
The invention has the advantages that:The 1st, 3 print heads are set, print head is transported freely in guide rail upper edge X, Y, Z three-dimensional It is dynamic, artificial trachea internal layer, artificial trachea middle layer, artificial trachea outer layer can be printed respectively simultaneously, can control and improve well The mechanical property of people's person's windpipe.2nd, 3D printing and ultrasonic vibration are subjected to compound prepare and process artificial trachea, in print procedure In promote three layers of combination due to ultrasonic vibration, and the internal layer of artificial trachea is by adjusting the conjunction direction of vibration of workbench And bionical surface micro-structure is formed, there is good body mechanics' sexual function.3rd, the internal layer of artificial trachea of the present invention uses Collagen is carbon fiber without generating biocompatible, good biocompatibility, middle layer, light and intensity, and high outer layer is silicon Glue, good toughness are suitble to human body requirements, and printing effect is high, production cost is low, convenient for manufacture.In manufacture of intraocular tracheae field Have a vast market application prospect.
Description of the drawings
Fig. 1 is the artificial trachea structure diagram that prints of the present invention, in figure, 24-artificial trachea internal layer;In 25-artificial trachea Interbed;
26-artificial trachea outer layer;
Fig. 2 vibrates 3D printer structure diagrams for three composite ultraphonics of the present invention, in figure, 1-print head;2-feeding roller
3—YGuide rail;4—XGuide rail;5—YGuide rail;6—XGuide rail;7-feeding roller;8—YGuide rail;9—XGuide rail;10-print head;11—ZGuide rail;12—ZGuide rail;13-print head;14-feeding roller; 15-body;16-active operation platen;17-ultrasonic vibration installation;18-ultrasonic vibration installation;19—ZGuide rail;
Fig. 3 is the adjustable ultrasonic movable table structure diagram of the present invention, in figure, 16-active operation platen;20-push Plate;21-attachment screw;22-top board;23-attaching nut;17-ultrasonic vibration installation;18-ultrasonic vibration installation; Fig. 4 is the artificial trachea scanning electron microscope (SEM) photograph for preparing of the present invention, in figure, a-internal layer micro-structure b-middle layer micro-structure c-outer Layer micro-structure.
Specific embodiment
It is as follows for embodiment for the present invention is better described:
Embodiment 1
Artificial tracheae 3D printing equipment of the present invention is made of electronic section, printer and software, and wherein electronic section includes System board, mainboard, motor driving plate, temperature control panel, heating tube, thermocouple, hott bed;Printer includes print head, feed roll Cylinder, guide rail, which is characterized in that X, Y, Z three-dimensional guide rail are set on printer body 15, and X, Y, Z-direction guide rail are respectively along each Three row are arranged in order into from direction, X guide rails are respectively 4,6,9;Y guide rail is respectively 3,5,8;Z guide rails are respectively 11,12,19.Often A Y guide rail is connected respectively along Y-direction with body, and each X guide rails connect Y guide rail by sliding block;Each Z guide rails are connected by sliding block Connect X guide rails.
Y guide rail 5, Y guide rail 8, Y guide rail 3 are moved along Y-direction, and X guide rails 6, X guide rails 9, X guide rails 4 are by sliding block respectively in Y Guide rail 5, Y guide rail 8, Y guide rail 3 are moved along Y-direction, and Z guide rails 19, Z guide rails 11, Z guide rails 12 are led by sliding block in X guide rails 6, X respectively Rail 9, X guide rails 4 are along X to moving.
Three print heads of printer setup 1,10,13, three print heads by sliding block be separately fixed at three Z guide rails 11, 12nd, it on 19, is moved along Z-direction.
Each print head 1,10,13 connects respective feeding roller 2 by conveying pipeline, and 7,14, feeding roller, which is fixed on, to be beaten It prints on body 15.
Printer organism bottom is equipped with excusing from death wave working plate, and excusing from death wave working plate is by active operation platen 16, two Platform ultrasonic vibration installation 17,18 forms, and every excusing from death device is fixed on work by upper and lower pressing plate 20,22 and screw 21, nut 22 On dynamic working plate 16, also, arc groove is had in direction in length and breadth in active operation platen upper edge pallet face, ultrasound is adjusted The installation site of vibrating device makes ultrasonic movable table that can carry out the conjunction ultrasonic vibration of horizontal any direction.
Embodiment 2
Manufacture of intraocular tracheae technical process of the present invention is as follows:
Step 1 establishes the three-dimensional digital printer model of artificial trachea:It is calculated according to mechanical property and experiment test, it is and right Than the mechanical property of popularity pipe, material composition, three layers of structure, concrete shape and size according to artificial trachea, design is artificial The thickness ratio of three interlayer of tracheae.
Step 2 prepares three kinds of 3D printing materials of collagen, carbon fiber, silica gel for 3D printing.
Step 3 adjusts the installation site of two ultrasonic vibration installations of ultrasonic movable table and fixes, adjusts it Oscillation Amplitude is 0.1 millimeter, vibration frequency 20kHz.
The three-dimensional digitalization model of artificial trachea is imported printer apparatus, printing flow is set, with 0.3 by step 4 The outer layer of the printhead prints artificial trachea of millimeter, with the middle layer of 0.2 millimeter of printhead prints artificial trachea, with 0.1 milli The internal layer of the printhead prints artificial trachea of rice.Inner layer material is collagen, and intermediate layer material is carbon fiber, and cladding material is Silica gel.
Application examples 3
The artificial trachea of printing is removed, carries out mechanical property tests, and mechanical property comparative analysis is carried out with popularity pipe, if It needs, redesigns the thickness ratio of three interlayers of artificial trachea.
The interior wall tissue structural experiment of artificial trachea is done, and is compared and analyzed with popularity inside pipe wall structure, determines ultrasound The installation direction of vibrating device, vibration frequency, amplitude ultrasonic vibration relevant parameter.
Duplicate printing optimizes the structure and process parameter optimizing of artificial trachea, and manufacture is suitable for clinical practice and popularity pipe The artificial trachea of Performance Match.
The artificial tracheal energy index such as following table in part prepared by the present invention:(It is compared with existing commercially available product)
Sample ID Stretch condition Breaking state Radial crushing strength
Sell artificial trachea in existing market Linearly Brittle fracture 65% crushing of compression
Artificial trachea prepared by the present invention It is non-linear Ductile rupture 76% crushing of compression
As can be seen that compared with conventional printing apparatus, the mechanical property of artificial trachea produced by the present invention, the fingers such as toughness, intensity Mark is superior to artificial trachea made from conventional printing apparatus, and have good bionic surface micro-structure, is conducive to clinical practice.

Claims (3)

1. a kind of special ultrasonic 3D printing equipment of artificial trachea, is made of, printer includes beating electronic device, printer and software Print head, feeding roller, guide rail, which is characterized in that X, Y, Z three-dimensional guide rail, X, Y guide rail edge respectively are set on printer body X, Y-direction is connected with body, and Z guide rails connect X guide rails by sliding block, and X guide rails connect Y guide rail by sliding block;X, Y, Z-direction are led Rail is arranged in order into three row along respective direction respectively;
Three print heads of printer setup, three print heads are separately fixed on three Z guide rails by sliding block, are transported along Z-direction It is dynamic;
Each print head connects respective feeding roller by conveying pipeline, and feeding roller is fixed on printing body;
Printer organism bottom be equipped with excusing from death wave working plate, excusing from death wave working plate by active operation platen, two or more Platform ultrasonic vibration installation forms, and ultrasonic vibration installation is fixed on active operation platen by upper and lower pressing plate and screw, and And have arc groove in direction in length and breadth in active operation platen upper edge pallet, adjust the installation site of ultrasonic vibration installation.
It is 2. special using the special ultrasonic 3D printing equipment Compound Machining artificial trachea technique of artificial trachea described in claim 1 Sign is, is achieved by the steps of:
Step 1 establishes the three-dimensional digital printer model of artificial trachea:It is calculated according to mechanical property and experiment test, it is and right Than the mechanical property of popularity pipe, material composition, three layers of structure, concrete shape and size according to artificial trachea, design is artificial The thickness ratio of three interlayer of tracheae;
Step 2 prepares three kinds of 3D printing materials of collagen, carbon fiber, silica gel for 3D printing;
Step 3 adjusts the installation site of the ultrasonic vibration installation of ultrasonic movable table and fixes, adjusts its Oscillation Amplitude, Vibration frequency;
The three-dimensional digitalization model of artificial trachea is imported printing device, sets printing flow, three print heads are adopted by step 4 It is printed with needle diameter print head of different sizes;Inner layer material is collagen, and intermediate layer material is carbon fiber, outer layer Material is silica gel.
3. the special ultrasonic 3D printing equipment Compound Machining artificial trachea technique of artificial trachea is utilized as claimed in claim 2, It is characterized in that, selects the outer layer of 0.3 millimeter of printhead prints artificial trachea, with 0.2 millimeter of printhead prints artificial trachea Middle layer, with the internal layer of 0.1 millimeter of printhead prints artificial trachea.
CN201810208935.7A 2018-03-14 2018-03-14 A kind of special ultrasonic 3D printing equipment of artificial trachea and complex machining process Pending CN108248029A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810208935.7A CN108248029A (en) 2018-03-14 2018-03-14 A kind of special ultrasonic 3D printing equipment of artificial trachea and complex machining process

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Application Number Priority Date Filing Date Title
CN201810208935.7A CN108248029A (en) 2018-03-14 2018-03-14 A kind of special ultrasonic 3D printing equipment of artificial trachea and complex machining process

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113524662A (en) * 2021-07-08 2021-10-22 吉林大学 Jet polishing assisted electric arc ultrasonic composite multi-material 3D printing device and method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104085111A (en) * 2014-07-11 2014-10-08 东莞中国科学院云计算产业技术创新与育成中心 Multi-nozzle 3D printer and method for controlling speed and precision of multi-nozzle 3D printer
CN105172135A (en) * 2015-07-23 2015-12-23 南京师范大学 Printing method of multi-sprayer high-speed FDM model
CN106985385A (en) * 2017-04-16 2017-07-28 吉林大学 Compound material ultrasound deposits increasing material manufacturing device and method

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104085111A (en) * 2014-07-11 2014-10-08 东莞中国科学院云计算产业技术创新与育成中心 Multi-nozzle 3D printer and method for controlling speed and precision of multi-nozzle 3D printer
CN105172135A (en) * 2015-07-23 2015-12-23 南京师范大学 Printing method of multi-sprayer high-speed FDM model
CN106985385A (en) * 2017-04-16 2017-07-28 吉林大学 Compound material ultrasound deposits increasing material manufacturing device and method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113524662A (en) * 2021-07-08 2021-10-22 吉林大学 Jet polishing assisted electric arc ultrasonic composite multi-material 3D printing device and method

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Application publication date: 20180706

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