CN108245149A - A kind of mouse rat-tail pulse non-invasive blood pressure rapid measurement device - Google Patents

A kind of mouse rat-tail pulse non-invasive blood pressure rapid measurement device Download PDF

Info

Publication number
CN108245149A
CN108245149A CN201810055633.0A CN201810055633A CN108245149A CN 108245149 A CN108245149 A CN 108245149A CN 201810055633 A CN201810055633 A CN 201810055633A CN 108245149 A CN108245149 A CN 108245149A
Authority
CN
China
Prior art keywords
cercoids
tail
rat
pulse
mouse
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201810055633.0A
Other languages
Chinese (zh)
Other versions
CN108245149B (en
Inventor
杨波
徐尔夫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chengdu Techman Software Co Ltd
Original Assignee
Chengdu Techman Software Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chengdu Techman Software Co Ltd filed Critical Chengdu Techman Software Co Ltd
Priority to CN201810055633.0A priority Critical patent/CN108245149B/en
Publication of CN108245149A publication Critical patent/CN108245149A/en
Application granted granted Critical
Publication of CN108245149B publication Critical patent/CN108245149B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021Measuring pressure in heart or blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00Evaluating a particular growth phase or type of persons or animals
    • A61B2503/40Animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • A61D2003/003Appliances for supporting or fettering animals for operative purposes with head or neck restraining means

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Pathology (AREA)
  • Physiology (AREA)
  • Animal Husbandry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Catching Or Destruction (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

The invention discloses a kind of mouse rat-tail pulse non-invasive blood pressure rapid measurement devices, including system host, experiment pallet and the mouse cage being arranged on experiment pallet, mouse cephalostat, rat-tail fixator are equipped in mouse cage, the adjustable plate being arranged on experiment pallet is further included, pulse block device is equipped on adjustable plate successively, pressure cercoids, pulse transducer, draws cercoids.Adjustable plate rear end is fixed on using shaft on experiment pallet, is followed closely by the hand for screwing front end and is realized the lifting of front end around fixing axle rotation, highly consistent so as to adjust block device axle center and rat-tail;Draw cercoids that can be moved forward and backward, while draw the pressing plate on cercoids that can also be moved forward and backward, the rat-tail that the two combination is suitable for different length is fixed;Draw cercoids that will integrally be pulled back after compressing rat-tail by rolling the knob of tail end, so that it is guaranteed that rat-tail is in smooth exceptionally straight state;Eventually by adjustment rat-tail height and stretch rat-tail and realize the accurate blood pressure for measuring rat-tail.

Description

A kind of mouse rat-tail pulse non-invasive blood pressure rapid measurement device
Technical field
The present invention relates to medical experiment apparatus fields, and in particular to a kind of mouse rat-tail pulse non-invasive blood pressure quickly measures dress It puts.
Background technology
Rat-tail pulse non-invasive blood pressure measuring system is used using the tail sleeve method no-invasive measurement of blood pressure principle of current prevalence in the world The observation of animal artery blood pressure in chronic experiment, animal are not required to anesthesia, hurtless measure, easy to use.Measuring system includes host With measuring device two large divisions, host mainly plays control and data dissection, and measuring device mainly plays execution and data acquisition Effect.Measuring device is made of experiment pallet, rat-tail pulse block device, rat-tail pulse transducer, several big components of mouse cage, due to big The mouse build measuring device that differs greatly is divided into as rat measuring device and mouse measuring device.Rat build is bigger than normal to be easy to Control, so rat rat-tail Woundless blood pressure measuring device is comparative maturity at present.And mouse build is less than normal, active, body is clever It is living not easy to control, it is difficult to collect effective pulse signal in experiment.
Invention content
It is an object of the invention to overcome the deficiencies of the prior art and provide a kind of mouse rat-tail pulse non-invasive blood pressures quickly to survey Measure device.By adjusting rat-tail height and stretch rat-tail and realize the accurate blood pressure for measuring rat-tail.
The purpose of the present invention is achieved through the following technical solutions:A kind of mouse rat-tail pulse non-invasive blood pressure is quickly surveyed Device is measured, including system host, pallet and the mouse cage being arranged on the experiment pallet is tested, mouse head is equipped in the mouse cage Fixator, rat-tail fixator, it is characterised in that:The adjustable plate being arranged on experiment pallet is further included, on the adjustable plate successively Equipped with pulse block device, pressure cercoids, pulse transducer, cercoids is drawn, adjustable plate is fixed far from pulse block device side equipped with shaft Seat, the shaft fixing block are equipped with shaft, and adjustable plate is equipped with hand screw II close to pulse block device side.
Preferably, the mouse cephalostat, rat-tail fixator top be equipped with and notch and twisted with the matched hand of notch Screw I, mouse cephalostat, rat-tail fixator are connected by hand screw I with mouse cage.
Preferably, mouse cage deck is fixed on the experiment pallet, the mouse cage, the mouse cephalostat, rat-tail are fixed Device is arranged on mouse cage deck, the material of mouse cage using transparent acrylic, the mouse cephalostat, rat-tail fixator material adopt It is aoxidized with aluminum component.
Preferably, the pulse block device structure annular in shape is arranged with natural rubber, pulse on pulse block device internal ring wall Block device lateral surface is equipped with a gas nozzle, and the gas nozzle is connected with the cavity volume that natural rubber wraps up.
Preferably, the pressure cercoids include pressure cercoids housing, the pressure cercoids soft rubber cushion being arranged in pressure cercoids housing and And pressure cercoids handwheel, pressure cercoids screw rod on the cercoids housing are arranged on, the both sides of the pressure cercoids housing are equipped with groove, The pressure cercoids handwheel lifts to adjust pressure cercoids screw rod.
Preferably, the pulse transducer includes pulse transducer housing, is equipped in the pulse transducer housing high-precision Pulse transducer module and suitable electronic device are spent, the high-precision pulse sensor assembly and suitable electronic device are respectively with being System host Electricity Federation.
Preferably, the pulse transducer housing includes pulse transducer upper cover, pulse transducer lower cover, and the pulse passes The upper surface of sensor upper cover is covered on pulse transducer in concave and to place mouse rat-tail and is equipped with a through-hole, pulse senses Device upper cover forms a circular cavity with pulse transducer lower cover, and sensor pressing plate, the sensor are equipped in the circular cavity The lower end of pressing plate is connect with sensor, and the upper end of sensor pressing plate is equipped with sensor soft rubber cushion, and the sensor soft rubber cushion passes through Through-hole and to place rat-tail;The side wall of the pulse transducer housing be equipped with positioning convex platform, the positioning convex platform with it is described The fit depressions of cercoids housing both sides are pressed, the bottom of pulse transducer housing is equipped with buckle.
Preferably, the drawing cercoids includes slide, guide rod, draws cercoids pressing plate, and the slide both sides are provided with mounting hole, The guide rod is mounted in mounting hole, and slide upper surface is coated with slide soft rubber cushion, and the slide soft rubber cushion upper surface is in cone Connected in star, the end face of slide soft rubber cushion, which is equipped with, draws cercoids screw rod and draws the matched pressing handwheel of cercoids screw rod with described, slides Slide screw rod is additionally provided on seat, the slide screw rod is equipped with the slip handwheel coordinated with it;The drawing cercoids pressing plate is mounted on On guide rod, the bottom of cercoids pressing plate is drawn to be provided with and draws cercoids soft rubber cushion.
Preferably, the adjustable plate is equipped with height limit block, card slot, wire casing, sliding slot, mounting groove, the height limit Block is arranged on adjustable plate far from drawing cercoids side, and the card slot is to fixed pulse transducer housing, and the wire casing is fettering Cable, the sliding slot to realize draw cercoids slide, the mounting groove to place slide screw rod and slide handwheel.
The beneficial effects of the invention are as follows:
1. the mouse cage of three kinds of specifications covers the mouse of different weight size, it can ensure that mouse body by comprehensive package, fixed effect Fruit is more preferable.
2. the mouse cage outer diameter of three kinds of specifications is identical, using same mouse cage deck, dress takes convenient and efficient.
3. adjustable plate rear end using shaft be fixed on experiment pallet on, by screw front end hand follow closely around fixing axle rotation come Realize the lifting of front end, it is highly consistent so as to adjust block device axle center and rat-tail.
4. drawing cercoids that can be moved forward and backward, while draw the pressing plate on cercoids that can also be moved forward and backward, the two combination is suitable for The rat-tail of different length is fixed.
5. draw cercoids that will integrally be pulled back after compressing rat-tail by rolling the knob of tail end, so that it is guaranteed that rat-tail is in flat Whole exceptionally straight state.
6. draw the rubber cushion shape wrapped up on cercoids slide that pre-large post-small conical socket, the change with rat-tail geomery is presented Change unanimously, covered effect is good.
7. mouse cephalostat is made of aluminum component, thermal conductivity is high, good heat dissipation effect, and mouse head is not easy raw sweat in experiment.
8. the device is integrally-regulated flexibly, bound strong, adaptable for the mouse of different building shape.
9. mouse body posture is naturally, comfort is good, experimental efficiency is high, can quickly obtain experimental waveform data.
Description of the drawings
Fig. 1 is the overall structure diagram of the present invention;
Fig. 2 is the A-A sectional views in Fig. 1;
Fig. 3 is the partial enlarged view of part B in Fig. 2;
Fig. 4 is the vertical view of the present invention;
Fig. 5 is the left view of the present invention;
Fig. 6 is the right view of the present invention;
In figure, 1- experiment pallets, 2- mouse cage decks, 31- mouse cages, 32- mouse cephalostats, 33- rat-tail fixators, 34- hands twist spiral shell Follow closely I, 4- height limit blocks, 5- shaft fixing blocks, 51- shafts, 6- adjustable plates, 61- hand screws II, 62- tension discs, 71- arteries and veins It fights sensor lower cover, 72- pulse transducer upper covers, 73- sensor pressing plates, 74- sensor soft rubber cushions, 81- pressure cercoids housings, 82- pressure cercoids screw rods, 83- pressure cercoids handwheels, 84- pressure cercoids soft rubber cushions, 9- pulse block devices, 101- slides, 102- slides are soft Rubber cushion, 103- guide rods, 104- draw cercoids pressing plate, and 105- draws cercoids soft rubber cushion, 106- pressing handwheels, and 107- draws cercoids screw rod, 108- slides handwheel, 101-1- slide screw rods.
Specific embodiment
Technical scheme of the present invention is described in further detail below in conjunction with the accompanying drawings, but protection scope of the present invention is not limited to It is as described below.
Embodiment
As shown in figures 1 to 6, a kind of mouse rat-tail pulse non-invasive blood pressure rapid measurement device, including system host, experiment support Disk 1 and the mouse cage 31 being arranged on experiment pallet 1, mouse cage 31 is interior to be equipped with mouse cephalostat 32, rat-tail fixator 33, further includes The adjustable plate 6 being arranged on experiment pallet 1, be equipped with successively on adjustable plate 6 pulse block device 9, pressure cercoids 8, pulse transducer 7, Draw cercoids 10.By pulse block device 9, pressure cercoids 8, pulse transducer 7, cercoids 10 is drawn to be sequentially fixed on adjustable plate 6, it adjusts Plate 6 is equipped with shaft fixing block 5 far from 9 side of pulse block device, and shaft fixing block 5 is equipped with shaft 51, and adjustable plate 6 is close to pulse 9 side of block device is equipped with hand screw II 61, by adjusting adjustable plate 6, that is, adjust hand screw II 61 make 6 front end of adjustable plate around Shaft fixing block 5 moves up and down, to cause the axle center of pulse block device 9 and rat-tail highly consistent, meanwhile, pressure cercoids 8 makes pulse Sensor 7 is close to rat-tail, and cercoids 10 is drawn to also ensure that entire rat-tail is in smooth exceptionally straight state while rat-tail is compressed, So as to ensure the accuracy of pressure value measured using the device.
It is highly preferred that the top of mouse cephalostat 32, rat-tail fixator 33 be equipped with notch and with the matched hand of notch Screw 34 is twisted, mouse cephalostat 32, rat-tail fixator 33 are connected by hand screw I 34 with mouse cage 31.Spiral shell is twisted by adjusting hand I 34 are followed closely to realize the adjustment of mouse cephalostat 32,33 position of rat-tail fixator,
It is highly preferred that being fixed with mouse cage deck 2 on experiment pallet 1, mouse cage 31, mouse cephalostat 32, rat-tail fixator 33 are set On mouse cage deck 2, the material of mouse cage 31 is using transparent acrylic, the material use of mouse cephalostat 32, rat-tail fixator 33 Aluminum component aoxidizes, and 31 outer diameter of mouse cage is unified for φ 32mm in the present invention, and internal diameter has tri- kinds of φ 23mm, φ 25mm, φ 27mm specifications, right The length difference tri- kinds of specifications of 80mm, 85mm, 90mm answered, wherein internal diameter φ 23mm are suitable for 15-25g mouse, internal diameter φ 25mm Suitable for 25-35g mouse, internal diameter φ 27mm are suitable for 35-45g mouse;32 outer diameter of mouse cephalostat has φ 22.5mm, φ Tri- kinds of 24.5mm, φ 26.5mm specifications, match respectively with 31 internal diameter of the mouse cage of three kinds of specifications.Inside is taper circular hole, corresponds to three Kind outer diameter is respectively φ 9- φ 19mm, φ 9- φ 21mm, φ 9- φ 23mm, and the notch size of rat-tail fixator 33 is respectively Long 16mm wide 6mm, long 15mm wide 5.5mm, long 14mm wide 5mm correspond to the mouse cage 31 of three kinds of specifications respectively.The mouse cage of three kinds of specifications 31, cover the mouse of different weight size, can ensure that mouse body by comprehensive package, fixed effect is more preferable.Three kinds of specifications 31 outer diameter of mouse cage is identical, and using same mouse cage deck 2, dress takes convenient and efficient.
It is highly preferred that 9 structure annular in shape of pulse block device, natural rubber, pulse are arranged on 9 internal ring wall of pulse block device 9 lateral surface of block device is equipped with a gas nozzle, and gas nozzle is connected with the cavity volume that natural rubber wraps up.
It is highly preferred that pressure cercoids 8 includes pressure cercoids housing 81, the pressure cercoids soft rubber cushion 84 being arranged in pressure cercoids housing 81 And pressure cercoids handwheel 83, pressure cercoids screw rod 82 on cercoids housing 81 are arranged on, the both sides of pressure cercoids housing 81 are equipped with groove, Pressure cercoids handwheel 83 lifts to adjust pressure cercoids screw rod 82.
It is highly preferred that pulse transducer 7 includes pulse transducer housing, high-precision pulse is equipped in pulse transducer housing Sensor assembly and suitable electronic device, high-precision pulse sensor assembly and suitable electronic device are electric with system host respectively Connection.
It is highly preferred that pulse transducer housing includes pulse transducer upper cover 72, pulse transducer lower cover 71, the pulse In concave and to place mouse rat-tail, pulse transducer upper cover 72 is equipped with a through-hole, arteries and veins for the upper surface of sensor upper cover 72 Sensor upper cover 72 of fighting forms a circular cavity 75 with pulse transducer lower cover 71, and 75 are equipped with sensor pressure in the circular cavity Plate 73, the lower end of the sensor pressing plate 73 are connect with sensor, and the upper end of sensor pressing plate 73 is equipped with sensor soft rubber cushion 74, The sensor soft rubber cushion 74 passes through through-hole and to place rat-tail;The side wall of pulse transducer housing is equipped with positioning convex platform, Positioning convex platform and the fit depressions of 81 both sides of pressure cercoids housing, the bottom of pulse transducer housing are equipped with buckle.Experiment mice Rat-tail passes through pulse block device 9, is then caught in pulse block device 9 in the card slot of pulse transducer lower cover 71.Adjustment hand twists spiral shell Following closely II 61 makes 6 front end of adjustable plate fixed seat 5 moves up and down around the shaft, until pulse block device 9 is located substantially with experiment mice rat-tail In sustained height;Meanwhile make the rat-tail of experiment mice in order, and it is made to keep straight in pulse transducer upper cover 72, it then will pressure Cercoids 8 is slipped into along the positioning convex platform of pulse transducer upper cover 72, slides into the front end of pulse transducer upper cover 72, is revolved counterclockwise Turning pressure cercoids handwheel 83 makes pressure cercoids screw rod 82 be moved down with dynamic pressure cercoids soft rubber cushion 84 by the front end appropriateness pressure of experiment mice Tightly.During rat-tail is compressed, sensor soft rubber cushion 74 supports rat-tail, sensor soft rubber cushion together with pulse transducer upper cover 72 74 main support points, as rat-tail is compacted so that sensor soft rubber cushion 74, sensor pressing plate 73 and cell pressure sense It is sensitiveer, the accuracy of detection data is improved, meanwhile, sensor soft rubber cushion 74 plays cushioning effect, eliminates the uneasiness of mouse Sense improves the accuracy of detection data.
It is highly preferred that cercoids 10 is drawn to include slide 101, guide rod 103, draws cercoids pressing plate 104, the setting of 101 both sides of slide There is mounting hole, guide rod 103 is mounted in mounting hole, and 101 upper surface of slide is coated with slide soft rubber cushion 102, and the slide is soft The tapered groove in 102 upper surface of rubber cushion, the end face of slide soft rubber cushion 102, which is equipped with, draws cercoids screw rod 107 and with drawing cercoids screw rod 107 matched pressing handwheels 106 are additionally provided with slide screw rod 101-1 on slide 101, and slide screw rod 101-1 is equipped with to be matched with it The slip handwheel 108 of conjunction;Cercoids pressing plate 104 is drawn to be mounted on guide rod 103, the bottom of cercoids pressing plate 104 is drawn to be provided with drawing tail Device soft rubber cushion 105.
It is highly preferred that adjustable plate 6 is equipped with height limit block 4, card slot, wire casing, sliding slot, mounting groove, height limit block 4 is set It puts in adjustable plate 6 far from drawing cercoids 10 side, card slot is to fixed pulse transducer housing, and wire casing is fettering cable, sliding slot To realize draw cercoids 10 slide, mounting groove to place slide screw rod 101-1 and slide handwheel 108.
The course of work of the present invention:
1. before experiment, mouse cage 31, mouse cephalostat 32, rat-tail fixator 33 from mouse cage deck 2 are removed, rotate clockwise pressure tail Device handwheel 83 makes pressure cercoids screw rod 82 move on to topmost, and pulse block device 9 and pressure cercoids 8 from pulse transducer 7 are removed, rolled The dynamic handwheel 108 that slides carrys out moving sliding base 101 so as to which cercoids 10 will be drawn to move on to close to pulse transducer 7, rotatably compresses hand counterclockwise Wheel 106 will draw cercoids pressing plate 104 to unclamp.
2. rotation hand screw I 34 is unscrewed counterclockwise, rat-tail fixator 33 is removed, mouse cephalostat 32 is moved on into mouse cage 31 Front end.Experiment mice is headfirst put into mouse cage 31 from the side for removing rat-tail fixator 33, back towards upper abdomen downward, Then rat-tail fixator 33 is attached to mouse cage 31 again, the tail of experiment mice is blocked, tightened by the card slot of rat-tail fixator 33 Hand screw I 34 fastens rat-tail fixator 33.Mouse cephalostat 32 is adjusted to suitable position, it is ensured that experiment mice body quilt Securely limitation, tightens hand screw I 34 and fixes mouse cephalostat 32.
3. mouse cage component 3 is caught in mouse cage deck 2, it is moved forward and backward to the position away from the about 3-6mm of pulse transducer 7, rotation Mouse cage component 3 makes mouse figure keep vertical.
4. experiment mice rat-tail passes through pulse block device 9, pulse block device 9 is then caught in pulse transducer lower cover 71 In card slot.Adjustment hand screw II 61 makes 6 front end of adjustable plate, and fixed seat 5 moves up and down around the shaft, up to pulse block device 9 and in fact It tests mouse rat-tail and is substantially at sustained height.
5. making the rat-tail of experiment mice in order, it is made to keep straight in pulse transducer upper cover 72, it then will 8 edge of pressure cercoids The positioning convex platform of pulse transducer upper cover 72 slips into, and slides into the front end of pulse transducer upper cover 72, counterclockwise rotation pressure tail Device handwheel 83 makes pressure cercoids screw rod 82 be moved down with dynamic pressure cercoids soft rubber cushion 84 by the front end appropriateness compression of experiment mice.
Cercoids pressing plate 104 is drawn 6. opening, the rear end of experiment mice rat-tail is lain in the slide soft rubber cushion 102 for drawing cercoids 10 On, it rolls slip handwheel 108 and carrys out moving sliding base 101 so that the rear end of experiment mice rat-tail is completely disposed in slide soft rubber cushion 102. Drawing cercoids pressing plate 104 on mobile guide bar 103 slides into experiment mice rat-tail tail end on slide 101, will draw cercoids screw rod 107 are moved to and cercoids pressing plate 104 are drawn to slot corresponding position, close and draw cercoids pressing plate 104 by the tail end of experiment mice rat-tail It covers, rotates clockwise pressing handwheel 106 with cercoids pressing plate 104 is drawn moderately to compress experiment mice rat-tail, roll and slide handwheel 108 to carry out moving sliding base 101 exceptionally straight by experiment mice rat-tail.
7. experiment pallet 1 is put into the Laboratory Module of system host, connection pulse block device 9 and 7 cable of pulse transducer To system host, open host and start data acquisition.Can cercoids handwheel 83 and pressing handwheel be pressed by rotation in experimentation 106 come that the crush of regulation experiment mouse rat-tail and rolling slides that handwheel 108 carrys out regulation experiment mouse rat-tail draw in journey Degree, so as to adjust the size waveforms of measurement data.
The above is only the preferred embodiment of the present invention, it should be understood that the present invention is not limited to described herein Form is not to be taken as the exclusion to other embodiment, and available for other combinations, modifications, and environments, and can be at this In the text contemplated scope, modifications can be made through the above teachings or related fields of technology or knowledge.And those skilled in the art institute into Capable modifications and changes do not depart from the spirit and scope of the present invention, then all should be in the protection domain of appended claims of the present invention It is interior.

Claims (9)

1. a kind of mouse rat-tail pulse non-invasive blood pressure rapid measurement device, including system host, experiment pallet(1)And it is arranged on The experiment pallet(1)On mouse cage(31), the mouse cage(31)It is interior to be equipped with mouse cephalostat(32), rat-tail fixator(33), It is characterized in that:It further includes and is arranged on experiment pallet(1)On adjustable plate(6), the adjustable plate(6)On successively be equipped with pulse hinder Disconnected device(9), pressure cercoids(8), pulse transducer(7), draw cercoids(10), adjustable plate(6)Far from pulse block device(9)Side is equipped with Shaft fixing block(5), the shaft fixing block(5)It is equipped with shaft(51), adjustable plate(6)Close to pulse block device(9)Side Equipped with hand screw II(61).
2. a kind of mouse rat-tail pulse non-invasive blood pressure rapid measurement device according to claim 1, it is characterised in that:It is described Mouse cephalostat(32), rat-tail fixator(33)Top be equipped with notch and hand screw matched with notch I(34), mouse Cephalostat, rat-tail fixator pass through hand screw I(34)With mouse cage(31)It is connected.
3. a kind of mouse rat-tail pulse non-invasive blood pressure rapid measurement device according to claim 1 or 2, it is characterised in that: The experiment pallet(1)On be fixed with mouse cage deck(2), the mouse cage(31), the mouse cephalostat(32), rat-tail fixator (33)It is arranged on mouse cage deck(2)On, mouse cage(31)Material using transparent acrylic, the mouse cephalostat(32), rat-tail Fixator(33)Material using aluminum component aoxidize.
4. a kind of mouse rat-tail pulse non-invasive blood pressure rapid measurement device according to claim 1, it is characterised in that:It is described Pulse block device(9)Structure annular in shape, pulse block device(9)Natural rubber, pulse block device are arranged on internal ring wall(9)Outside Face is equipped with a gas nozzle, and the gas nozzle is connected with the cavity volume that natural rubber wraps up.
5. a kind of mouse rat-tail pulse non-invasive blood pressure rapid measurement device according to claim 1, it is characterised in that:It is described Press cercoids(8)Including pressure cercoids housing (81), the pressure cercoids soft rubber cushion being arranged in pressure cercoids housing (81)(84)And setting Pressure cercoids handwheel (83), pressure cercoids screw rod (82) on the pressure cercoids housing (81), the two of the pressure cercoids housing (81) Side is equipped with groove, and the pressure cercoids handwheel (83) lifts to adjust pressure cercoids screw rod (82).
6. a kind of mouse rat-tail pulse non-invasive blood pressure rapid measurement device according to claim 5, it is characterised in that:It is described Pulse transducer(7)Including pulse transducer housing, high-precision pulse sensor assembly is equipped in the pulse transducer housing And suitable electronic device, the high-precision pulse sensor assembly and suitable electronic device respectively with system host Electricity Federation.
7. a kind of mouse rat-tail pulse non-invasive blood pressure rapid measurement device according to claim 6, it is characterised in that:It is described Pulse transducer housing includes pulse transducer upper cover(72), pulse transducer lower cover (71), the pulse transducer upper cover (72) in concave and to place mouse rat-tail, pulse transducer upper cover (72) is equipped with a through-hole, pulse sensing for upper surface Device upper cover (72) forms a circular cavity (75) with pulse transducer lower cover (71), and (75) are equipped with sensor in the circular cavity Pressing plate (73), the lower end of the sensor pressing plate (73) are connect with sensor, and the upper end of sensor pressing plate (73) is equipped with sensor Soft rubber cushion (74), the sensor soft rubber cushion (74) is across through-hole and to place rat-tail;The side of the pulse transducer housing Wall is equipped with positioning convex platform, the positioning convex platform and the fit depressions of described pressure cercoids housing (81) both sides, pulse transducer The bottom of housing is equipped with buckle.
8. a kind of mouse rat-tail pulse non-invasive blood pressure rapid measurement device according to claim 1, it is characterised in that:It is described Draw cercoids(10)Including slide(101), guide rod(103), draw cercoids pressing plate(104), the slide(101)Both sides are provided with peace Fill hole, the guide rod(103)In mounting hole, slide(101)Upper surface is coated with slide soft rubber cushion(102), it is described Slide soft rubber cushion(102)The tapered groove in upper surface, slide soft rubber cushion(102)End face be equipped with draw cercoids screw rod(107)And With the drawing cercoids screw rod(107)Matched pressing handwheel(106), slide(101)On be additionally provided with slide screw rod(101-1), The slide screw rod(101-1)It is equipped with the slip handwheel coordinated with it(108);The drawing cercoids pressing plate(104)Mounted on leading To bar(103)On, draw cercoids pressing plate(104)Bottom be provided with draw cercoids soft rubber cushion(105).
9. a kind of mouse rat-tail pulse non-invasive blood pressure rapid measurement device according to claim 1, it is characterised in that:It is described Adjustable plate(6)It is equipped with height limit block(4), card slot, wire casing, sliding slot, mounting groove, the height limit block(4)It is arranged on tune Save plate(6)Far from drawing cercoids(10)Side, the card slot is to fixed pulse transducer housing, and the wire casing is to lashing wire Cable, the sliding slot is realizing drawing cercoids(10)It slides, the mounting groove is placing slide screw rod(101-1)With slip handwheel (108).
CN201810055633.0A 2018-01-19 2018-01-19 Mouse tail pulse noninvasive blood pressure rapid measuring device Active CN108245149B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810055633.0A CN108245149B (en) 2018-01-19 2018-01-19 Mouse tail pulse noninvasive blood pressure rapid measuring device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810055633.0A CN108245149B (en) 2018-01-19 2018-01-19 Mouse tail pulse noninvasive blood pressure rapid measuring device

Publications (2)

Publication Number Publication Date
CN108245149A true CN108245149A (en) 2018-07-06
CN108245149B CN108245149B (en) 2020-11-24

Family

ID=62741916

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810055633.0A Active CN108245149B (en) 2018-01-19 2018-01-19 Mouse tail pulse noninvasive blood pressure rapid measuring device

Country Status (1)

Country Link
CN (1) CN108245149B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111000652A (en) * 2019-12-24 2020-04-14 华中科技大学同济医学院附属协和医院 Experimental mouse rapid fixing device and using method thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1282566A (en) * 1999-08-02 2001-02-07 中国药科大学 Method and equipment for indirectly measuring blood pressure by rat tail pulses
US20080168948A1 (en) * 2007-01-11 2008-07-17 Starr Life Sciences Corp. Small animal restraining device with non-traumatic animal loading device
CN201790807U (en) * 2010-09-21 2011-04-13 河北医科大学 Non-invasive heart-rate monitor for small animals
CN103622761A (en) * 2013-12-16 2014-03-12 中国人民解放军第三军医大学第一附属医院 Binding device for small animal
CN205163304U (en) * 2015-11-26 2016-04-20 西北民族大学 Mouse mount
CN107212871A (en) * 2017-07-18 2017-09-29 成都泰盟软件有限公司 Mouse rat-tail Woundless blood pressure measuring device

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1282566A (en) * 1999-08-02 2001-02-07 中国药科大学 Method and equipment for indirectly measuring blood pressure by rat tail pulses
US20080168948A1 (en) * 2007-01-11 2008-07-17 Starr Life Sciences Corp. Small animal restraining device with non-traumatic animal loading device
CN201790807U (en) * 2010-09-21 2011-04-13 河北医科大学 Non-invasive heart-rate monitor for small animals
CN103622761A (en) * 2013-12-16 2014-03-12 中国人民解放军第三军医大学第一附属医院 Binding device for small animal
CN205163304U (en) * 2015-11-26 2016-04-20 西北民族大学 Mouse mount
CN107212871A (en) * 2017-07-18 2017-09-29 成都泰盟软件有限公司 Mouse rat-tail Woundless blood pressure measuring device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111000652A (en) * 2019-12-24 2020-04-14 华中科技大学同济医学院附属协和医院 Experimental mouse rapid fixing device and using method thereof

Also Published As

Publication number Publication date
CN108245149B (en) 2020-11-24

Similar Documents

Publication Publication Date Title
CN107212871B (en) Mouse tail noninvasive blood pressure measuring device
CN106963376B (en) A kind of Low ESR brain fax sense electrode device based on independent point of circle buffer structure
CN108245149A (en) A kind of mouse rat-tail pulse non-invasive blood pressure rapid measurement device
CN112461514A (en) A withstand voltage testing arrangement for panel computer surface screen
CN109497987A (en) A kind of electrocardioscanner
CN106628393A (en) Bagging tool
CN208065368U (en) A kind of Neurology is with recovery bed
CN210673306U (en) Little white mouse heart rate experiment measuring device
CN208725910U (en) A kind of Breast Surgery postoperative care bracket
CN209154899U (en) Heat lamp is used in a kind of nursing
CN208823813U (en) Multifunctional blood-purifying laser therapeutic instrument
CN208837399U (en) A kind of Intelligent seat
CN207367462U (en) A kind of multifunctional cardiopulmonary recovery pressing model with guiding and limiting device
CN206167299U (en) Novel health detection seat
CN104970782B (en) A set of device that primate blood pressure is measured for waking state
CN206239860U (en) A kind of anesthesia with quantitative feeding is threaded a needle thorn bogey
CN201727509U (en) Elastic electrode cap for electroencephalogram (EEG) examination
CN206434324U (en) Health examination all-in-one with electrocardio monitoring function
CN207745480U (en) A kind of portable racket
CN213891395U (en) Sensor pressing device
CN213373439U (en) Gynaecology and obstetrics is with sheltering from inspection bed board device
CN202801711U (en) Remote ischemic preconditioning training instrument
CN209332607U (en) Gastrocopy pillow
CN215078410U (en) Portable body fat computer
CN221450608U (en) Body fat measurement health scale

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant