CN103622761A - Binding device for small animal - Google Patents

Binding device for small animal Download PDF

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Publication number
CN103622761A
CN103622761A CN201310689253.XA CN201310689253A CN103622761A CN 103622761 A CN103622761 A CN 103622761A CN 201310689253 A CN201310689253 A CN 201310689253A CN 103622761 A CN103622761 A CN 103622761A
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CN
China
Prior art keywords
restraint device
toy
connecting device
tail cover
headgear
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Granted
Application number
CN201310689253.XA
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Chinese (zh)
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CN103622761B (en
Inventor
王涛
任小宝
孙溦
熊建琼
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Third Military Medical University TMMU
First Affiliated Hospital of TMMU
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First Affiliated Hospital of TMMU
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Priority to CN201310689253.XA priority Critical patent/CN103622761B/en
Publication of CN103622761A publication Critical patent/CN103622761A/en
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Publication of CN103622761B publication Critical patent/CN103622761B/en
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Abstract

The invention discloses a binding device of a small animal. The binding device comprises a binding device, a head sleeve and a tail sleeve, wherein the binding device is barrel-shaped, one end of the binding device is closed and the other end of the binding device is provided with an opening; the head sleeve is sheathed with one closed end of the binding device and is provided with a first connecting device; the tail cover is sheathed with one end, with the opening, of the binding device and is provided with a second connecting device matched with the first connecting device, and the bottom of the tail sleeve covering the opening is provided with a through hole through which the tail of the small animal passes. The binding device disclosed by the invention has the advantages that the rear legs can be prevented from pedaling out of the binding device when the experiment animal flounders, and when the binding device is matched with a non-invasive blood pressure monitoring system for use, the purpose of binding the experimental animal is effectively achieved, so that the benefit to shortening the monitoring time and improving the monitoring accuracy is achieved.

Description

A kind of toy restraint device
Technical field
The present invention relates to medical experiment device technique field, particularly a kind of toy restraint device.
Background technology
Animal blood pressure is detected, in medical experiment, have very important significance, traditional animal blood pressure monitoring need to be anaesthetized animal before detection, then animal is cut to the operation technique that skin, muscle separation and vascular catheterization etc. have wound, these have the operation technique of wound to make the fluctuation of monitoring of blood pressure result of animal larger, and the result that causes detection is not the legitimate reading that empirical factor causes; Meanwhile, due to after an animal surgery, can not carry out continuous several times, long monitoring of blood pressure, thereby a large amount of wastes laboratory animal resource, do not meet the animal welfare principle of scientific experiments requirement yet.In recent years, along with scientific and technical development, noninvasive physiological and pathological detection technique is widely used in medical scientific.Wherein, toy Non-invasive blood pressure monitoring systems, owing to laboratory animal is not had to wound evil in operating process, has effectively been avoided testing bias and the interference that other factor causes monitoring result, thereby has been made experimental result more genuine and believable.
Although the toy Non-invasive blood pressure monitoring systems that prior art Zhong, U.S. DSI company produces can effectively be avoided the drawback of above-mentioned traditional monitoring of blood pressure, accomplishes non-invasive monitoring.Yet, it usually occurs that for fettering three separated sticky tie rods of constraint bag tail end of clear-headed laboratory animal animal constraint is tight, it is not firm to fix and animal back leg is very easily pedaled out uropore when intersecting bonding constraint animal, thereby cause monitoring of blood pressure data unstable, extend monitoring time, reduce the degree of accuracy of monitoring.
Therefore, how a kind of toy restraint device is provided, can effectively fetter laboratory animal, prevent that laboratory animal back leg from pedaling out restraint device, when supporting the use with Non-invasive blood pressure monitoring systems, contribute to shorten monitoring time, improve monitoring accuracy, become those skilled in the art's important technological problems urgently to be resolved hurrily.
Summary of the invention
In view of this, the invention provides a kind of toy restraint device, to reach, can effectively fetter laboratory animal, prevent that laboratory animal back leg from pedaling out restraint device, when supporting the use with Non-invasive blood pressure monitoring systems, shorten monitoring time, improve the object of monitoring accuracy.
For achieving the above object, the invention provides following technical scheme:
A toy restraint device, for non-invasive blood pressure monitoring, comprising:
Restraint device, is tubular, one end sealing, and the other end is provided with opening;
Headgear, is set in one end that described restraint device seals, and is provided with the first connecting device on it;
Tail cover, is set in one end that described restraint device is provided with opening, is provided with the second connecting device coordinating with described the first connecting device on it, and described tail cover covers and on the bottom on described opening, is provided with the through hole passing for toy tail.
Preferably, described restraint device is columniform steel mesh.
Preferably, described headgear front end is provided with taper and closes up, and closes up and coordinate with described taper in one end of described restraint device sealing.
Preferably, described the first connecting device is provided with a plurality of, is evenly distributed on described headgear, corresponding, described tail puts and is provided with described second connecting device corresponding with described the first connecting device quantity.
Preferably, described the first connecting device is nylon hook strip, and described the second connecting device is nylon floss band; Or described the first connecting device is nylon floss band, described the second connecting device is nylon hook strip.
Preferably, described the first connecting device is provided with two, is distributed in symmetrically the end outside of described headgear, corresponding, described the second connecting device is provided with two, is distributed in symmetrically the front end inner side of described tail cover.
Preferably, the front end of described tail cover is provided with two symmetrical connecting portions, and described the second connecting device is arranged on the inner side of described connecting portion.
Preferably, the front end of described tail cover is provided with slide fastener.
Preferably, described slide fastener is provided with two, is distributed in symmetrically the front end of described tail cover.
Preferably, described headgear and described tail cover are made by cloth.
From technique scheme, can find out, toy restraint device provided by the invention, comprises restraint device, headgear and tail cover, and wherein, restraint device is tubular, one end sealing, and the other end is provided with opening, headgear is set in one end of restraint device sealing, is provided with the first connecting device on it, tail cover is set in one end that restraint device is provided with opening, on it, be provided with the second connecting device coordinating with the first connecting device, tail cover covers and on the bottom on opening, is provided with the through hole passing for toy tail, in use, first one end of restraint device sealing is fitted in headgear, then laboratory animal head is positioned in restraint device towards headgear direction, the tail of laboratory animal is passed from the through hole of tail cover, and tail cover is enclosed within to the other end of restraint device, the second connecting device that tail puts and the first connecting device on headgear are connected, with this, realize the constraint to laboratory animal, finally oversleeve type pressure transducer is set in to the proximal part of the laboratory animal tail passing from through hole, after animal peace and quiet are stable, measure its blood pressure.When the restraint device of this structure can prevent laboratory animal struggle, back leg is pedaled out restraint device, effectively reaches the object of constraint laboratory animal, when supporting the use with Non-invasive blood pressure monitoring systems, contributes to shorten monitoring time, improves the precision of monitoring.
Accompanying drawing explanation
In order to be illustrated more clearly in the embodiment of the present invention or technical scheme of the prior art, to the accompanying drawing of required use in embodiment or description of the Prior Art be briefly described below, apparently, accompanying drawing in the following describes is only some embodiments of the present invention, for those of ordinary skills, do not paying under the prerequisite of creative work, can also obtain according to these accompanying drawings other accompanying drawing.
The perspective view of the toy restraint device that Fig. 1 provides for the embodiment of the present invention;
Top view after the toy restraint device that Fig. 2 provides for the embodiment of the present invention coordinates;
Side view after the toy restraint device that Fig. 3 provides for the embodiment of the present invention coordinates;
Front view after the toy restraint device that Fig. 4 provides for the embodiment of the present invention coordinates;
Rearview after the toy restraint device that Fig. 5 provides for the embodiment of the present invention coordinates;
The structural representation of the restraint device of the toy restraint device that Fig. 6 provides for the embodiment of the present invention;
The structural representation of the headgear of the toy restraint device that Fig. 7 provides for the embodiment of the present invention;
The structural representation of the tail cover of the toy restraint device that Fig. 8 provides for the embodiment of the present invention.
The specific embodiment
The invention provides a kind of toy restraint device, to reach, can effectively fetter laboratory animal, prevent that laboratory animal back leg from pedaling out restraint device, shorten monitoring time, improve the object of monitoring accuracy.
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described, obviously, described embodiment is only the present invention's part embodiment, rather than whole embodiment.Embodiment based in the present invention, those of ordinary skills, not making the every other embodiment obtaining under creative work prerequisite, belong to the scope of protection of the invention.
Refer to Fig. 1-Fig. 5, the perspective view of the toy restraint device that Fig. 1 provides for the embodiment of the present invention; Top view after the toy restraint device that Fig. 2 provides for the embodiment of the present invention coordinates; Side view after the toy restraint device that Fig. 3 provides for the embodiment of the present invention coordinates; Front view after the toy restraint device that Fig. 4 provides for the embodiment of the present invention coordinates; Rearview after the toy restraint device that Fig. 5 provides for the embodiment of the present invention coordinates.
A kind of toy restraint device provided by the invention, comprises restraint device 7, headgear 8 and tail cover 4.
Wherein, restraint device 7, for holding laboratory animal, is tubular, one end sealing, and the other end is provided with opening, by opening, laboratory animal is put into or taken out restraint device 7; Headgear 8 is set in one end of restraint device 7 sealings, is provided with the first connecting device 1 on it; Tail cover 4 is set in one end that restraint device 7 is provided with opening, is provided with the second connecting device 3 coordinating with the first connecting device 1 on it, and tail cover is provided with the through hole 5 passing for toy tail on 4 bottoms that cover on opening.
Compared with prior art, toy restraint device provided by the invention, in use, first one end of restraint device 7 sealings is fitted in headgear 8, then laboratory animal head is positioned in restraint device 7 towards headgear 8 directions, the tail of laboratory animal is passed from the through hole 5 of tail cover 4, and tail cover 4 is enclosed within to the other end of restraint device 7, the second connecting device 3 on tail cover 4 is connected with the first connecting device 1 on headgear 8, with this, realize the constraint to laboratory animal, finally oversleeve type pressure transducer is set in to the proximal part of the laboratory animal tail passing from through hole 5, after animal peace and quiet are stable, measure its blood pressure.
The restraint device 7 of this structure, by headgear 8 and tail cover 4, can protect operator by laboratory animal, not bitten, after the first connecting device 1 and the second connecting device 3 are connected simultaneously, restraint device 7 is wrapped completely by headgear 8 and tail cover 4, by laboratory animal and isolation, reduce the stimulation of external environment to laboratory animal, avoid laboratory animal frightened struggle in observation process; In addition, on tail cover 4, be provided with the manhole that only can make laboratory animal tail pass through, laboratory animal other body parts except tail are all strapped in restraint device completely, when this design can effectively prevent laboratory animal struggle, back leg is pedaled out restraint device 7, effectively reach the object of constraint laboratory animal, when supporting the use with Non-invasive blood pressure monitoring systems, contribute to shorten monitoring time, improve the precision of monitoring.
Restraint device 7 can adopt various structures, various shape to realize, such as plastic barrel, glass infuser etc., in embodiments of the present invention, refer to Fig. 6, the structural representation of the restraint device of the toy restraint device that Fig. 6 provides for the embodiment of the present invention, restraint device 7 is columniform steel mesh, and steel mesh price is low, easily obtains, be convenient to make, compare easy cleaning simultaneously.
For fear of in operating process, before headgear 8 coordinates with tail cover 4, restraint device 7 slippage from headgear 8, in the embodiment of the present invention, refer to Fig. 7, the structural representation of the headgear of the toy restraint device that Fig. 7 provides for the embodiment of the present invention, headgear 8 front ends are provided with taper and close up, close up and coordinate with described taper in one end of restraint device 7 sealings, this structure can make fastening being enclosed within on restraint device 7 of headgear 8, avoids restraint device 7 slippages.
In order to guarantee that headgear 8 and tail overlap 4 secure fit, avoid coming off in use procedure, in the embodiment of the present invention, the first connecting device 1 is provided with a plurality of, is evenly distributed on headgear 8, corresponding, on tail cover 4, be provided with described second connecting device 3 corresponding with the first connecting device 1 quantity, by the connecting device of many assembly cover is set, can make headgear 8 and tail overlap 4 be connected more fastening, avoid coming off.
The first connecting device 1 and the second connecting device 3 can adopt various ways to realize, and in embodiments of the present invention, the first connecting device 1 is nylon hook strip, and the second connecting device 3 is nylon floss band; Or the first connecting device 1 is nylon floss band, the second connecting device 3 is nylon hook strip.Adopt nylon floss band and nylon hook strip to use as connecting device simple, they are combined and are slightly gently pressed, just can produce larger fastening power and tear-off power, save time, fast, nylon floss band and nylon hook strip are convenient to be fixed on headgear 8 and tail cover 4 simultaneously.
In operating process, need first headgear 8 to be enclosed within on restraint device 7, in the end tail cover 4 is being enclosed within on restraint device 7 and by connecting device and is being connected with headgear 8, therefore, preferably, the first connecting device 1, one in nylon floss band and nylon hook strip namely, on headgear 8, be provided with two, be distributed in symmetrically the end outside of headgear 8, corresponding with it, the second connecting device 3, namely another in nylon floss band and nylon hook strip, is provided with two, is distributed in symmetrically the front end inner side of tail cover 4.The first connecting device 1 is provided with to headgear 8 end outsides, and the second connecting device 3 is arranged on the front end inner side of tail cover 4, is convenient to headgear 8 and overlaps being connected between 4 with tail.
The second connecting device 3 is arranged on to tail and overlaps 4 front end inner sides, in tail cover 4 processes of advancing along restraint device 7, than the impact that is easier to be subject to the first connecting device 1, cause advancing not smooth, extend the time of monitoring preparation, therefore, in order to be further convenient to the first connecting device 1, be connected with the second connecting device 3, in the embodiment of the present invention, refer to Fig. 8, the structural representation of the tail cover of the toy restraint device that Fig. 8 provides for the embodiment of the present invention, the front end of tail cover 4 is provided with two symmetrical connecting portions 2, the second connecting device 3 is arranged on the inner side of connecting portion 2, like this, the second connecting device 3 is arranged on to tail and overlaps 4 front ends independently on connecting portion 2, in operating process, when tail cover 4 is enclosed within on restraint device 7, can first the connecting portion with the second connecting device 32 upwards be dug, after tail cover 4 moves into place, turning down flicking, make it to be connected with the first connecting device 1.
For the ease of be convenient to observation experiment animal state in observation process, or after having monitored, be convenient to tail cover 4 to back off, in the embodiment of the present invention, the front end of tail cover 4 is provided with slide fastener 6, in operating process, can at any time slide fastener 6 be opened or closure, meet operator's instructions for use.Further, slide fastener 6 is provided with two, is distributed in symmetrically the front end of tail cover 4.
Headgear 8 and tail cover 4 can adopt multiple material to make, in embodiments of the present invention, headgear 8 and tail cover 4 are made by cloth, the headgear 8 that cloth is made and tail cover 4 can be good at being wrapped on restraint device 7, make toy restraint device provided by the invention play better constraint effect.
The present invention also provides the animal constraint bag of Liao Yizu DSI company and contrast experiment's data of toy restraint device provided by the invention.In experiment, adopt 10 experimental rats as experimental subject, use respectively animal constraint bag and the toy restraint device provided by the invention constraint experimental rat of DSI company, then measure its blood pressure, and record each animal and be fixedly accomplished to the interval between monitoring of blood pressure success, and both difference relatively.Entered replication 10 times, use the animal constraint bag of DSI company, it is (14.0 ± 4.3) min that animal blood pressure is measured average consuming time, and toy restraint device provided by the invention, it is (7.9 ± 2.5) min that animal blood pressure is measured average consuming time, as can be seen here, use toy restraint device provided by the invention fixedly during animal its monitoring of blood pressure consuming time significantly lower than the like product (P < 0.01) of DSI company.
In this description, each embodiment adopts the mode of going forward one by one to describe, and each embodiment stresses is the difference with other embodiment, between each embodiment identical similar part mutually referring to.
Above-mentioned explanation to the disclosed embodiments, makes professional and technical personnel in the field can realize or use the present invention.To the multiple modification of these embodiment, will be apparent for those skilled in the art, General Principle as defined herein can, in the situation that not departing from the spirit or scope of the present invention, realize in other embodiments.Therefore, the present invention will can not be restricted to these embodiment shown in this article, but will meet the widest scope consistent with principle disclosed herein and features of novelty.

Claims (10)

1. a toy restraint device, for non-invasive blood pressure monitoring, is characterized in that, comprising:
Restraint device (7), is tubular, one end sealing, and the other end is provided with opening;
Headgear (8), is set in one end that described restraint device (7) seals, and is provided with the first connecting device (1) on it;
Tail cover (4), be set in one end that described restraint device (7) is provided with opening, on it, be provided with the second connecting device (3) coordinating with described the first connecting device (1), described tail cover (4) covers and on the bottom on described opening, is provided with the through hole (5) passing for toy tail.
2. toy restraint device according to claim 1, is characterized in that, described restraint device (7) is columniform steel mesh.
3. toy restraint device according to claim 1, is characterized in that, described headgear (8) front end is provided with taper and closes up, and closes up and coordinate with described taper in one end of described restraint device (7) sealing.
4. toy restraint device according to claim 1, it is characterized in that, described the first connecting device (1) is provided with a plurality of, be evenly distributed on described headgear (8), corresponding, on described tail cover (4), be provided with described second connecting device (3) corresponding with described the first connecting device (1) quantity.
5. toy restraint device according to claim 4, is characterized in that, described the first connecting device (1) is nylon hook strip, and described the second connecting device (3) is nylon floss band; Or described the first connecting device (1) is nylon floss band, described the second connecting device (3) is nylon hook strip.
6. toy restraint device according to claim 5, it is characterized in that, described the first connecting device (1) is provided with two, be distributed in symmetrically the end outside of described headgear (8), corresponding, described the second connecting device (3) is provided with two, is distributed in symmetrically the front end inner side of described tail cover (4).
7. toy restraint device according to claim 6, is characterized in that, the front end of described tail cover (4) is provided with two symmetrical connecting portions (2), and described the second connecting device (3) is arranged on the inner side of described connecting portion (2).
8. toy restraint device according to claim 1, is characterized in that, the front end of described tail cover (4) is provided with slide fastener (6).
9. toy restraint device according to claim 8, is characterized in that, described slide fastener (6) is provided with two, is distributed in symmetrically the front end of described tail cover (4).
10. toy restraint device according to claim 1, is characterized in that, described headgear (8) and described tail cover (4) are made by cloth.
CN201310689253.XA 2013-12-16 2013-12-16 A kind of toy restraint device Expired - Fee Related CN103622761B (en)

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Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
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CN103622761A true CN103622761A (en) 2014-03-12
CN103622761B CN103622761B (en) 2016-01-20

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104720923A (en) * 2015-01-16 2015-06-24 宁波大学 Mouse binding device
CN105613333A (en) * 2014-10-29 2016-06-01 刘一敏 Pet headgear
CN105796205A (en) * 2016-03-10 2016-07-27 济南大学 Fixing device for collecting blood of jugular venous sinus of rattus norvegicus
CN108245149A (en) * 2018-01-19 2018-07-06 成都泰盟软件有限公司 A kind of mouse rat-tail pulse non-invasive blood pressure rapid measurement device
CN111317590A (en) * 2020-02-27 2020-06-23 中国人民解放军疾病预防控制中心 Adjustable rat restraint device for noninvasive blood pressure monitoring

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5975028A (en) * 1998-06-12 1999-11-02 St. Jude Children's Research Hospital Comfortable animal restraint
US20080168948A1 (en) * 2007-01-11 2008-07-17 Starr Life Sciences Corp. Small animal restraining device with non-traumatic animal loading device
CN202458772U (en) * 2012-03-13 2012-10-03 黑龙江八一农垦大学 Device for fixing experimental mouse
CN202821707U (en) * 2012-10-22 2013-03-27 上海市杨浦区中心医院 Fixed device of experimental rat
CN202920409U (en) * 2012-12-16 2013-05-08 常陆林 A mouse fixer

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5975028A (en) * 1998-06-12 1999-11-02 St. Jude Children's Research Hospital Comfortable animal restraint
US20080168948A1 (en) * 2007-01-11 2008-07-17 Starr Life Sciences Corp. Small animal restraining device with non-traumatic animal loading device
CN202458772U (en) * 2012-03-13 2012-10-03 黑龙江八一农垦大学 Device for fixing experimental mouse
CN202821707U (en) * 2012-10-22 2013-03-27 上海市杨浦区中心医院 Fixed device of experimental rat
CN202920409U (en) * 2012-12-16 2013-05-08 常陆林 A mouse fixer

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105613333A (en) * 2014-10-29 2016-06-01 刘一敏 Pet headgear
CN104720923A (en) * 2015-01-16 2015-06-24 宁波大学 Mouse binding device
CN105796205A (en) * 2016-03-10 2016-07-27 济南大学 Fixing device for collecting blood of jugular venous sinus of rattus norvegicus
CN108245149A (en) * 2018-01-19 2018-07-06 成都泰盟软件有限公司 A kind of mouse rat-tail pulse non-invasive blood pressure rapid measurement device
CN108245149B (en) * 2018-01-19 2020-11-24 成都泰盟软件有限公司 Mouse tail pulse noninvasive blood pressure rapid measuring device
CN111317590A (en) * 2020-02-27 2020-06-23 中国人民解放军疾病预防控制中心 Adjustable rat restraint device for noninvasive blood pressure monitoring

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