CN107212871A - Mouse rat-tail Woundless blood pressure measuring device - Google Patents

Mouse rat-tail Woundless blood pressure measuring device Download PDF

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Publication number
CN107212871A
CN107212871A CN201710585675.0A CN201710585675A CN107212871A CN 107212871 A CN107212871 A CN 107212871A CN 201710585675 A CN201710585675 A CN 201710585675A CN 107212871 A CN107212871 A CN 107212871A
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CN
China
Prior art keywords
mouse
tail
rat
blood pressure
screw
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Granted
Application number
CN201710585675.0A
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Chinese (zh)
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CN107212871B (en
Inventor
杨波
徐尔夫
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Chengdu Techman Software Co Ltd
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Chengdu Techman Software Co Ltd
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Priority to CN201710585675.0A priority Critical patent/CN107212871B/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021Measuring pressure in heart or blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021Measuring pressure in heart or blood vessels
    • A61B5/02141Details of apparatus construction, e.g. pump units or housings therefor, cuff pressurising systems, arrangements of fluid conduits or circuits
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00Evaluating a particular growth phase or type of persons or animals
    • A61B2503/40Animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • A61D2003/003Appliances for supporting or fettering animals for operative purposes with head or neck restraining means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • A61D2003/006Appliances for supporting or fettering animals for operative purposes with leg or foot restraining means

Abstract

The invention discloses a kind of mouse rat-tail Woundless blood pressure measuring device, including experiment pallet, also include the mouse body fixation kit and pulse detection component being arranged on experiment pallet, wherein mouse body fixation kit is used for the body for limiting mouse, it is set to keep tranquil, pulse detection component is used to measure rat-tail blood pressure.The device can effectively limit the body and rat-tail of different size mouse, especially for small mouse, it is kept quite, be convenient for rat-tail blood pressure measurement, effectively improve the degree of accuracy of measurement.

Description

Mouse rat-tail Woundless blood pressure measuring device
Technical field
The present invention relates to medical experiment apparatus field, and in particular to a kind of mouse rat-tail Woundless blood pressure measuring device.
Background technology
Rat-tail pulse non-invasive blood pressure measuring system is used using the tail sleeve method no-invasive measurement of blood pressure principle of current prevalence in the world The observation of animal artery blood pressure in chronic experiment, animal is not required to anesthesia, hurtless measure, easy to use.Measuring system includes main frame With measurement apparatus two large divisions, main frame mainly plays control and data dissection, and measurement apparatus mainly plays execution and data acquisition Effect.Measurement apparatus is made up of experiment pallet, rat-tail pulse block device, rat-tail pulse transducer, several big parts of mouse cage, due to big The mouse build measurement apparatus that differs greatly is divided into rat with measurement apparatus and mouse measurement apparatus again.Rat build is bigger than normal to be easy to Control, so rat rat-tail Woundless blood pressure measuring device is comparative maturity at present.And mouse build is less than normal, active, body is clever It is living whard to control, it is difficult to collect effective pulse signal in experiment.
The content of the invention
In order to solve the above-mentioned technical problem, the present invention discloses a kind of mouse rat-tail Woundless blood pressure measuring device, the device energy Enough bodies and rat-tail for effectively limiting different size mouse, especially for small mouse, make it keep quite, are convenient for Rat-tail blood pressure measurement, effectively improves the degree of accuracy of measurement.
The present invention is achieved through the following technical solutions:
Mouse rat-tail Woundless blood pressure measuring device, including experiment pallet, in addition to the mouse body being arranged on experiment pallet are consolidated Determine component and pulse detection component, wherein mouse body fixation kit is used for the body for limiting mouse, it is kept tranquil, pulse detection Component is used to measure rat-tail blood pressure.
The mouse body fixation kit include mouse cage, mouse cephalostat, rat-tail fixator and mouse body pressing plate, mouse cephalostat and Rat-tail fixator position in mouse cage can freely be adjusted, and height of the mouse body pressing plate in mouse cage can be adjusted freely, and mouse cage is The strip through-hole of two genesis analysis is provided with the top of the cylinder of accumbency, mouse cage, two strip through-holes are distributed in both sides at the top of mouse cage.
In the present invention, mouse cephalostat and rat-tail fixator are respectively used to limit head and the afterbody of mouse, mouse body pressing plate For aiding in mouse cage to limit mouse body position, mouse cephalostat and rat-tail the fixator position in mouse cage can freely be adjusted, Height of the mouse body pressing plate in mouse cage can be adjusted freely, therefore mouse body fixation kit of the present invention can be used in limiting different length With the mouse body of size, it is remained stationary as, beneficial to rat-tail blood pressure measurement is carried out, improve accuracy of measurement.
The taper circular hole matched with mouse head is provided with the inside of the mouse cephalostat, mouse cephalostat uses dark-coloured opaque material Expect, and mouse cephalostat is matched with mouse cage.
The rat-tail fixator is matched with mouse cage, and rat-tail fixator inner side end is inclined-plane, is provided with rat-tail fixator Bar hole, the inner side end and end face outside of bar hole connection rat-tail fixator.
Mouse cephalostat is provided with taper circular hole, is easy to fix mouse head, using dark-coloured opaque material, when mouse head When portion is placed in mouse cephalostat, keeps tranquil because visual field dark can be beneficial to mouse, make the physiology of mouse and keep at heart Calmness, thus the rat-tail blood pressure data measured is more authentic and valid, improves accuracy of measurement.
Rat-tail fixator inner side end is inclined-plane, is just consistent with mouse body tail end profile, improves mouse tail end and fixes Effect, while also lifting the comfort level of rat tail, is more favorable for mouse and quickly calms down, and improves testing efficiency, bar hole For rat-tail to be stretched out, it is placed in pulse detection component and carries out blood pressure measurement.
The mouse cephalostat and rat-tail retainer top are equipped with screw, the screw of mouse cephalostat and twist spiral shell provided with hand Hand screw two is provided with nail one, the screw of rat-tail fixator, the top of hand screw one passes through the strip through-hole on front side of mouse cage, hand The top of screw two is twisted through the strip through-hole on rear side of mouse cage.
Mouse cephalostat and rat-tail fixator are fixed in mouse cage by hand screw one and hand screw two, are passed through simultaneously The cooperation of hand screw one and hand screw two and two strip through-holes, realizes mouse cephalostat and rat-tail fixator in mouse cage Move freely.
The mouse body pressing plate is in the inner chamber of mouse cage, mouse cephalostat and the formation of rat-tail fixator, mouse body pressing plate following table Face is to carry on the back to be fixed with one layer of elastic cord breaker on the downside of the cambered surface matched, cambered surface with mouse, and the elastic cord breaker is specially medical silicon Rubber layer.
Mouse body pressing plate is used to limit position of the mouse in mouse cage, and its is Height Adjustable, is particularly suitable for use in small flexible The high mouse of degree, mouse body pressing plate lower surface is cambered surface, is fixed beneficial to fitting for mouse back, elastic cord breaker can be avoided always Mouse back is damaged, and improves mouse comfort level, makes it easier to keep tranquil.
The pulse detection component includes tail binder, pulse block device, pulse transducer and pulse transducer housing, described Pulse transducer housing is strip, and top is provided with rat-tail groove, and the pulse block device is solid close to mouse body located at rat-tail groove Determine the side of component, the pulse transducer is arranged in pulse transducer housing.
The pulse transducer housing of the rat-tail groove both sides is provided with positioning boss, and the tail binder is two and set Above rat-tail groove, tail binder includes housing, handwheel and screw rod, and housing bottom both sides are provided with the cunning matched with positioning boss Groove, the housing that housing bottom is provided with the middle part of strip groove, strip groove is provided with through hole, and screw rod is arranged in through hole, screw rod bottom Portion is connected with rat-tail pressing plate, and resilient material is wrapped up in rat-tail pressing plate periphery, and elastomeric material is medical grade silicon rubber, and the handwheel is located at Screwed hole is provided with the middle part of case top, handwheel, handwheel is located at screw rod upper end by screw thread borehole jack.
Tail binder is two, can preferably fix rat-tail, it is to avoid the rat-tail on its Bending Influence blood pressure measurement, tail binder Pressing plate can limit rat-tail position, therefore tail binder can be used in fixing various sizes of rat-tail.
The pulse block device is annular in shape, and inside is fixed with ring and sets pneumatic natural rubber ring, in pulse block device Outside is provided with valve, and valve is connected with the air cavity in natural rubber ring.
Two pilot holes and a screw are provided with the top of the mouse cage, screw is between two strip through-holes, the mouse body It is provided with the middle part of pressing plate in circular hole, circular hole and wears a threaded rod, threaded rod bottom is provided with limited block, limited block diameter is more than circular hole And limited block is placed in mouse body pressing plate and elastic buffer interlayer, the threaded rod upper end is through the screw at the top of mouse cage, in mouse body pressure Plate upper surface is additionally provided with two leads, and lead upper end passes through pilot hole.
The height of mouse body pressing plate is adjusted by rotating threaded rod, lead is used to limit mouse body pressing plate, it is to avoid it is with spiral shell Bar is rotated and rotated.
The mouse cage and mouse cephalostat side wall are provided with ordered series of numbers passage, a diameter of 4-5mm of passage.
The mouse cage is installed on pallet by mouse cage deck, provided with the card matched with mouse cage external diameter in the middle of mouse cage deck Groove, stopper slot of the experiment pallet both sides provided with fixed test cable.
The mouse cage and rat-tail fixator use transparent acrylic material.
The pulse transducer housing is provided with pulse block device neck, pulse block device card close to mouse body fixation kit one end In pulse block device neck.
The present invention compared with prior art, has the following advantages and advantages:
1st, mouse rat-tail Woundless blood pressure measuring device of the present invention, mouse cephalostat and rat-tail fixator are respectively used to limit always The head of mouse and afterbody, mouse body pressing plate are used to aid in mouse cage to limit mouse body position, and mouse cephalostat and rat-tail fixator exist Position can freely be adjusted in mouse cage, and height of the mouse body pressing plate in mouse cage can be adjusted freely, therefore mouse body of the present invention is fixed Component can be used in limiting different length and the mouse body of size, remain stationary as it, beneficial to rat-tail blood pressure measurement is carried out, carry The high measurement degree of accuracy;
2nd, mouse rat-tail Woundless blood pressure measuring device of the present invention, mouse cephalostat is provided with taper circular hole, is easy to fixed old Mouse head, using dark-coloured opaque material, when mouse head is placed in mouse cephalostat, because visual field dark can be beneficial to always Mouse keeps tranquil, makes the physiology of mouse and keeps tranquil at heart, thus the rat-tail blood pressure data measured is more authentic and valid, improves Accuracy of measurement.
Brief description of the drawings
Accompanying drawing described herein is used for providing further understanding the embodiment of the present invention, constitutes one of the application Point, do not constitute the restriction to the embodiment of the present invention.In the accompanying drawings:
Fig. 1 is schematic structural view of the invention;
Fig. 2 is top view of the present invention;
Fig. 3 is sectional view of the present invention;
Fig. 4 is rearview of the present invention;
Fig. 5 is tail binder of the present invention and pulse block device schematic diagram;
Fig. 6 is mouse body pressing plate schematic diagram of the present invention.
Mark and corresponding parts title in accompanying drawing:
1- tests pallet, 11- stopper slots, 2- mouse cages, 21- strip through-holes, 3- mouse cephalostats, 31- taper circular holes, 32- Hand screw one, 4- rat-tail fixators, 41- bar holes, 42- hand screws two, 5- mouse body pressing plates, 51- elastic cord breakers, 52- Threaded rod, 53- limited blocks, 54- leads, 6- tail binders, 61- housings, 611- chutes, 612- strip grooves, 62- handwheels, 63- Screw rod, 64- rat-tail pressing plates, 7- pulse block devices, 71- natural rubber rings, 72- valves, 8- pulse transducer housings, 81- rat-tails Groove, 82- positioning boss, 9- passages, 10- mouse cage decks, 101- necks.
Embodiment
For the object, technical solutions and advantages of the present invention are more clearly understood, with reference to embodiment and accompanying drawing, to this Invention is described in further detail, and exemplary embodiment and its explanation of the invention is only used for explaining the present invention, does not make For limitation of the invention.
As shown in figures 1 to 6, mouse rat-tail Woundless blood pressure measuring device of the present invention, including experiment pallet 1, in addition to be arranged at The mouse body fixation kit and pulse detection component on pallet 1 are tested, wherein mouse body fixation kit is used for the body for limiting mouse, made It keeps tranquil, and pulse detection component is used to measure rat-tail blood pressure.
The mouse body fixation kit includes mouse cage 2, mouse cephalostat 3, rat-tail fixator 4 and mouse body pressing plate 5, and mouse head is fixed Device 3 and rat-tail fixator 4 position in mouse cage 2 can freely be adjusted, and 5 height in mouse cage 2 of mouse body pressing plate can be adjusted freely Section, mouse cage 2 is the cylinder of accumbency, and the top of mouse cage 2 is provided with the strip through-hole 21 of two genesis analysis, and two strip through-holes 21 are distributed In the top both sides of mouse cage 2.
The inner side of mouse cephalostat 3 is provided with the taper circular hole 31 matched with mouse head, and mouse cephalostat 3 is using dark-coloured impermeable Bright material, mouse cephalostat 3 is matched with mouse cage 2 and can moved freely in mouse cage 2.
The rat-tail fixator 4 is matched with mouse cage 2 and can moved freely in mouse cage 2, the inner side end of rat-tail fixator 4 For inclined-plane, bar hole 41, the inner side end and outboard end of the connection rat-tail of bar hole 41 fixator 4 are provided with rat-tail fixator 4 Face.
The top of mouse cephalostat 3 and rat-tail fixator 4, which is equipped with screw, the screw of mouse cephalostat 3, is provided with hand Twist and hand screw 2 42 is provided with screw 1, the screw of rat-tail fixator 4, the top of hand screw 1 passes through the front side of mouse cage 2 Strip through-hole 21, strip through-hole 21 of the top of hand screw 2 42 through the rear side of mouse cage 2.
The mouse body pressing plate 5 is in the inner chamber of mouse cage 2, mouse cephalostat 3 and the formation of rat-tail fixator 4, mouse body pressing plate 5 Lower surface is to carry on the back to be fixed with one layer of elastic cord breaker 51 on the downside of the cambered surface matched, cambered surface with mouse, and the elastic cord breaker 51 is specific For medical grade silicon rubber layer.
Embodiment 2
As shown in figures 1 to 6, mouse rat-tail Woundless blood pressure measuring device of the present invention, including experiment pallet 1, in addition to be arranged at The mouse body fixation kit and pulse detection component on pallet 1 are tested, wherein mouse body fixation kit is used for the body for limiting mouse, made It keeps tranquil, and pulse detection component is used to measure rat-tail blood pressure.
The mouse body fixation kit includes mouse cage 2, mouse cephalostat 3, rat-tail fixator 4 and mouse body pressing plate 5, and mouse cage 2 is The cylinder of accumbency, the top of mouse cage 2 is provided with the strip through-hole 21 of two genesis analysis, and two strip through-holes 21 are distributed in mouse cage 2 and pushed up Portion both sides.
The inner side of mouse cephalostat 3 is provided with the taper circular hole 31 matched with mouse head, and mouse cephalostat 3 is using dark-coloured impermeable Bright material, mouse cephalostat 3 is matched with mouse cage 2 and can moved freely in mouse cage 2.
The rat-tail fixator 4 is matched with mouse cage 2 and can moved freely in mouse cage 2, the inner side end of rat-tail fixator 4 For inclined-plane, bar hole 41, the inner side end and outboard end of the connection rat-tail of bar hole 41 fixator 4 are provided with rat-tail fixator 4 Face.
The top of mouse cephalostat 3 and rat-tail fixator 4, which is equipped with screw, the screw of mouse cephalostat 3, is provided with hand Twist and hand screw 2 42 is provided with screw 1, the screw of rat-tail fixator 4, the top of hand screw 1 passes through the front side of mouse cage 2 Strip through-hole 21, strip through-hole 21 of the top of hand screw 2 42 through the rear side of mouse cage 2.
The mouse body pressing plate 5 is in the inner chamber of mouse cage 2, mouse cephalostat 3 and the formation of rat-tail fixator 4, mouse body pressing plate 5 Lower surface is to carry on the back to be fixed with one layer of elastic cord breaker 51 on the downside of the cambered surface matched, cambered surface with mouse, and the elastic cord breaker 51 is specific For medical grade silicon rubber layer.
The pulse detection component includes tail binder 6, pulse block device 7, pulse transducer and pulse transducer housing 8, The pulse transducer housing 8 is strip, and top is provided with rat-tail groove 81, and the pulse block device 7 is located at rat-tail groove 81 Close to the side of mouse body fixation kit, the pulse transducer is arranged in pulse transducer housing 8.
The pulse transducer housing 8 of the both sides of rat-tail groove 81 is provided with positioning boss 82, and the tail binder 6 is two And be arranged at the top of rat-tail groove 81, tail binder 6 includes housing 61, handwheel 62 and screw rod 63, the two bottom sides of housing 61 be provided with The chute 611 that positioning boss 82 is matched, the bottom of housing 61 is provided with strip groove 612, the housing 61 at the middle part of strip groove 612 and set There is through hole, screw rod 63 is arranged in through hole, the bottom of screw rod 63 is connected with rat-tail pressing plate 64, the periphery of rat-tail pressing plate 64 parcel is flexible Material, elastomeric material is medical grade silicon rubber, and the handwheel 62 is provided with screwed hole, handwheel located at the top of housing 61, the middle part of handwheel 62 62 are located at the upper end of screw rod 63 by screw thread borehole jack.
The pulse block device 7 is annular in shape, and inside is fixed with ring and sets pneumatic natural rubber ring 71, is blocked in pulse The outside of device 7 is provided with valve 72, and valve 72 is connected with the air cavity in natural rubber ring 71.
The top of mouse cage 2 is provided with two pilot holes and a screw, and screw is between two strip through-holes 21, the mouse The middle part of body pressing plate 5, which is provided with circular hole, circular hole, wears a threaded rod 52, and the bottom of threaded rod 52 is provided with limited block 53, limited block 53 Diameter is more than circular hole and limited block 53 is placed in mouse body pressing plate 5 and elastic buffer interlayer 51, and the upper end of threaded rod 52 passes through mouse cage 2 The screw at top, two leads 54 are additionally provided with the upper surface of mouse body pressing plate 5, and the upper end of lead 54 passes through pilot hole.
The side wall of mouse cage 2 and mouse cephalostat 3 is provided with ordered series of numbers passage 9, a diameter of 4-5mm of passage 9.
The mouse cage 2 is installed on pallet 1 by mouse cage deck 10, is provided with and the external diameter of mouse cage 2 in the middle of mouse cage deck 10 The neck 101 matched somebody with somebody, stopper slot 11 of experiment pallet 1 both sides provided with fixed test cable.
The mouse cage 2 and rat-tail fixator 4 use transparent acrylic material.
The pulse transducer housing 8 is provided with pulse block device neck, pulse block device 7 close to mouse body fixation kit one end It is arranged in pulse block device neck.
When carrying out blood pressure measurement to mouse, concrete operations are as follows:
Hand screw 2 42 is unscrewed, rat-tail fixator 4 is removed, rotating threaded rod 52 makes mouse body pressing plate 5 rise to highest, Unscrew hand screw 1, mouse cephalostat 3 is moved on into mouse cage 2 foremost;
The tail end of experiment mice from mouse cage 2 is put into, head is towards front, and upward, adjustment mouse cephalostat 3, which is arrived, to be closed at back Suitable position, tightens hand screw 1 and fixes whole mouse cephalostat 3;
Rat-tail fixator 4 is then placed in, is adjusted to behind suitable position tighten hand screw 2 42;
Rotating threaded rod 52 moves down mouse body pressing plate 5 to push down mouse body again;
Mouse body fixation kit is caught in mouse cage deck 10, movable mouse cage 2 is at distance away from pulse detection component Suitable position, rotation mouse cage 2 makes mouse figure keep vertical;
Rat-tail is passed through into pulse block device 7, then pulse block device 7 is caught in pulse block device neck;
Make rat-tail in order, it is unfolded in rat-tail groove 81,1 tail binder 6 is then snapped onto into pulse transducer housing 8 On, one end close to pulse block device 7 is slided into along positioning boss 82, rotation hand wheel 62 makes screw rod 63 move down before rat-tail End appropriateness is compressed;
Another tail binder 6 is caught in, the rear end appropriate location of pulse transducer housing 8 is slided into, rotation hand wheel 62 makes Screw rod 63, which is moved down, fixes rat-tail tail end;
Experiment pallet 1 is put into the Laboratory Module of system host, connection cables to system host, open system main frame starts It can move up and down screw rod 63 by rotating forward tail binder handwheel 62 in data acquisition, experimentation and adjust compression Amount, so as to adjust the waveform of measurement data.
Above-described embodiment, has been carried out further to the purpose of the present invention, technical scheme and beneficial effect Describe in detail, should be understood that the embodiment that the foregoing is only the present invention, be not intended to limit the present invention Protection domain, within the spirit and principles of the invention, any modification, equivalent substitution and improvements done etc. all should be included Within protection scope of the present invention.

Claims (10)

1. mouse rat-tail Woundless blood pressure measuring device, including experiment pallet (1), it is characterised in that also including being arranged at experiment support Mouse body fixation kit and pulse detection component on disk (1), wherein mouse body fixation kit are used for the body for limiting mouse, protect it Maintain an equal level quiet, pulse detection component is used to measure rat-tail blood pressure.
2. mouse rat-tail Woundless blood pressure measuring device according to claim 1, it is characterised in that the mouse body fixation kit Including mouse cage (2), mouse cephalostat (3), rat-tail fixator (4) and mouse body pressing plate (5), mouse cephalostat (3) and rat-tail are fixed Device (4) can be adjusted freely in mouse cage (2) interior position, and height of the mouse body pressing plate (5) in mouse cage (2) can be adjusted freely, mouse Cage (2) is the strip through-hole (21) that two genesis analysis are provided with the top of the cylinder of accumbency, mouse cage (2), two strip through-holes (21) It is distributed in both sides at the top of mouse cage (2).
3. mouse rat-tail Woundless blood pressure measuring device according to claim 2, it is characterised in that the mouse cephalostat (3) inner side is provided with the taper circular hole (31) matched with mouse head, and mouse cephalostat (3) is using dark-coloured opaque material, and mouse head is solid Determine device (3) to match with mouse cage (2).
4. mouse rat-tail Woundless blood pressure measuring device according to claim 2, it is characterised in that the rat-tail fixator (4) matched with mouse cage (2), rat-tail fixator (4) inner side end is inclined-plane, bar hole (41) be provided with rat-tail fixator (4), The inner side end and end face outside of bar hole (41) connection rat-tail fixator (4).
5. mouse rat-tail Woundless blood pressure measuring device according to claim 2, it is characterised in that the mouse cephalostat (3) and at the top of rat-tail fixator (4) it is equipped with screw, the screw of mouse cephalostat (3) and is provided with hand screw one (32), rat-tail It is provided with the top of hand screw two (42), hand screw one (32) through the bar shaped on front side of mouse cage (2) and leads in the screw of fixator (4) Through the strip through-hole (21) on rear side of mouse cage (2) at the top of hole (21), hand screw two (42).
6. mouse rat-tail Woundless blood pressure measuring device according to claim 2, it is characterised in that the mouse body pressing plate (5) In the inner chamber of mouse cage (2), mouse cephalostat (3) and rat-tail fixator (4) formation, mouse body pressing plate (5) lower surface is and mouse Carry on the back and be fixed with one layer of elastic cord breaker (51) on the downside of the cambered surface of matching, cambered surface.
7. mouse rat-tail Woundless blood pressure measuring device according to claim 1, it is characterised in that the pulse detection component Including tail binder (6), pulse block device (7), pulse transducer and pulse transducer housing (8), the pulse transducer housing (8) it is strip, top is consolidated provided with rat-tail groove (81), the pulse block device (7) located at rat-tail groove (81) close to mouse body Determine the side of component, the pulse transducer is arranged in pulse transducer housing (8).
8. mouse rat-tail Woundless blood pressure measuring device according to claim 7, it is characterised in that the rat-tail groove (81) The pulse transducer housing (8) of both sides is provided with positioning boss (82), and the tail binder (6) is two and is arranged at rat-tail groove (81) top, tail binder (6) includes housing (61), handwheel (62) and screw rod (63), and housing (61) two bottom sides are provided with and positioning The chute (611) of boss (82) matching, housing (61) bottom is provided with the housing in the middle part of strip groove (612), strip groove (612) Through hole is provided with, screw rod (63) is arranged in through hole, and screw rod (63) bottom is connected with rat-tail pressing plate (64), and rat-tail pressing plate (64) is outside Wrap up resilient material week, the handwheel (62) is provided with screwed hole, handwheel (62) at the top of housing (61) in the middle part of handwheel (62) Screw rod (63) upper end is located at by screw thread borehole jack.
9. mouse rat-tail Woundless blood pressure measuring device according to claim 7, it is characterised in that the pulse block device (7) annularly, inside is fixed with ring and sets pneumatic natural rubber ring (71), valve is provided with the outside of pulse block device (7) (72), valve (72) is connected with the air cavity in natural rubber ring (71).
10. mouse rat-tail Woundless blood pressure measuring device according to claim 6, it is characterised in that at the top of the mouse cage (2) Provided with two pilot holes and a screw, screw is between two strip through-holes (21), provided with circle in the middle part of the mouse body pressing plate (5) A threaded rod (52) is worn in hole, circular hole, threaded rod (52) bottom is provided with limited block (53), and limited block (53) diameter is more than circle Hole and limited block (53) is placed between mouse body pressing plate (5) and elastic cord breaker (51), threaded rod (53) upper end passes through mouse cage (2) The screw at top, two leads (54) are additionally provided with mouse body pressing plate (5) upper surface, and lead (54) upper end passes through pilot hole.
CN201710585675.0A 2017-07-18 2017-07-18 Mouse tail noninvasive blood pressure measuring device Active CN107212871B (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107928831A (en) * 2017-12-20 2018-04-20 中国科学院深圳先进技术研究院 Inject auxiliary fixing device
CN108186154A (en) * 2017-12-20 2018-06-22 中国科学院深圳先进技术研究院 Inject auxiliary fixing device
CN108245149A (en) * 2018-01-19 2018-07-06 成都泰盟软件有限公司 A kind of mouse rat-tail pulse non-invasive blood pressure rapid measurement device
CN108888381A (en) * 2018-06-27 2018-11-27 中国科学院微生物研究所 A kind of mouse tail vein fixing device for sampling blood
CN117547232A (en) * 2024-01-12 2024-02-13 成都泰盟软件有限公司 Method and system for calculating cardiac output of rat based on impedance method

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CN2689910Y (en) * 2004-01-18 2005-04-06 陈立 Hydraulic operation table for animal
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CN107928831A (en) * 2017-12-20 2018-04-20 中国科学院深圳先进技术研究院 Inject auxiliary fixing device
CN108186154A (en) * 2017-12-20 2018-06-22 中国科学院深圳先进技术研究院 Inject auxiliary fixing device
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CN108888381A (en) * 2018-06-27 2018-11-27 中国科学院微生物研究所 A kind of mouse tail vein fixing device for sampling blood
CN117547232A (en) * 2024-01-12 2024-02-13 成都泰盟软件有限公司 Method and system for calculating cardiac output of rat based on impedance method

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