CN108236681A - A kind of medicament for treating rhinitis - Google Patents

A kind of medicament for treating rhinitis Download PDF

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Publication number
CN108236681A
CN108236681A CN201611210771.9A CN201611210771A CN108236681A CN 108236681 A CN108236681 A CN 108236681A CN 201611210771 A CN201611210771 A CN 201611210771A CN 108236681 A CN108236681 A CN 108236681A
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CN
China
Prior art keywords
parts
grams
medicament
root
rhizoma
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CN201611210771.9A
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Chinese (zh)
Inventor
樊万军
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Individual
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Individual
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Priority to CN201611210771.9A priority Critical patent/CN108236681A/en
Publication of CN108236681A publication Critical patent/CN108236681A/en
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
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Abstract

The present invention relates to a kind of medicaments for treating rhinitis, it includes the substance of following weight proportioning：50 120 parts of the flower bud of lily magnolia, 50 120 parts of the root of Dahurain angelica, 50 120 parts of Rhizoma Atractylodis Macrocephalae, 20 50 parts of asarum, 50 120 parts of wrinkled giant hyssop, 100 200 parts of Radix Astragali, 50 80 parts of cicada slough, 20 70 parts of peppermint, windproof 50 70 parts, 100 120 parts of campanulaceae, 100 120 parts of grass-leaved sweetflag, 30 70 parts of the achene of Siberian cocklebur, 100 120 parts of honeysuckle, 100 120 parts of coix seed, 100 150 parts of Poria cocos, 100 120 parts of Fructus Forsythiae, 100 150 parts of lily, 100 120 parts of Rhizoma Chuanxiong, 100 120 parts of root of Chinese trichosanthes, 100 150 parts of dried orange peel, 100 120 parts of Fructus Aurantii, 1.2 2.0 parts of 1.0 1.6 parts of anarexol and chlorphenamine maleate.The medicament for the treatment of rhinitis of the present invention has the characteristics that at low cost, preparation is easy, toxic side effect is small, significant curative effect.

Description

A kind of medicament for treating rhinitis
Technical field
The present invention relates to tcm field, specifically, being related to a kind of medicament for treating rhinitis.
Background technology
Allergic rhinitis (allergic rhinitis, AR) is a kind of allergic disease, also known as " allergy Property rhinitis " is the allergic disease of nasal membrane, can cause multiple complications.Mostly with ictal rhiocnesmus, nasal obstruction, sneeze, flowing water Sample nasal mucus is cardinal symptom.Clinical classical symptom is presented with rhiocnesmus, sneeze, water sample nasal mucus, nasal obstruction.Rhiocnesmus and continuous spray It sneezes, frequent paroxysmal breaking-out, then nasal obstruction and nasal mucus, heavier with night from morning.Rhiocnesmus sees most patient, sometimes nose it is outer, Soft palate, face, external auditory canal etc. are itched, and Seasonal Incidence person's eye itching is more apparent.A large amount of clear water sample nasal mucus, but acute reaction becomes During to decrease or disappearance, it can reduce or retrogradation is turbid, secondary infection person becomes viscous purulence sample secretion.
Invention content
The object of the present invention is to provide a kind of medicaments for treating rhinitis.
In order to achieve the object of the present invention, a kind of medicament for treating rhinitis of present invention offer, a kind of medicament for treating rhinitis, It includes the substance of following weight proportioning：50-120 parts of the flower bud of lily magnolia, 50-120 parts of the root of Dahurain angelica, 50-120 parts of Rhizoma Atractylodis Macrocephalae, 20-50 parts of asarum, 50-120 parts of wrinkled giant hyssop, 100-200 parts of Radix Astragali, 50-80 parts of cicada slough, 20-70 parts of peppermint, 50-70 parts windproof, 100-120 parts of campanulaceae, 100-120 parts of grass-leaved sweetflag, 30-70 parts of the achene of Siberian cocklebur, 100-120 parts of honeysuckle, 100-120 parts of coix seed, 100-150 parts of Poria cocos, 100-120 parts of Fructus Forsythiae, 100-150 parts of lily, 100-120 parts of Rhizoma Chuanxiong, 100-120 parts of root of Chinese trichosanthes, 100-150 parts of dried orange peel, Fructus Aurantii 1.2-2.0 parts of 100-120 parts, 1.0-1.6 parts of anarexol and chlorphenamine maleate.
Preferably, the medicament for the treatment of rhinitis of the present invention includes the substance of following weight proportioning：80 parts of the flower bud of lily magnolia, the root of Dahurain angelica 80 Part, 80 parts of Rhizoma Atractylodis Macrocephalae, 30 parts of asarum, 80 parts of wrinkled giant hyssop, 150 parts of Radix Astragali, 60 parts of cicada slough, 50 parts of peppermint, 60 parts windproof, 110 parts of campanulaceae, 110 parts of grass-leaved sweetflag, 50 parts of the achene of Siberian cocklebur, 110 parts of honeysuckle, 110 parts of coix seed, 120 parts of Poria cocos, 110 parts of Fructus Forsythiae, 120 parts of lily, 110 parts of Rhizoma Chuanxiong, 110 parts of root of Chinese trichosanthes, 120 parts of dried orange peel, 110 parts of Fructus Aurantii, 1.2 parts of anarexol and chlorphenamine maleate 1.5 Part.
It is highly preferred that the medicament for the treatment of rhinitis of the present invention also includes the substance of following weight proportioning：Ten liang of leaves 150 Part, 150 parts of fourth last of the ten Heavenly stems grass, 150 parts of annual fleabane herb, 900 parts of garlic, 300 parts of aspongopus, 500 parts of rhizoma homalonemae, 900 parts of sargentodoxa cuneata, sword bean 600 parts, 150 parts of saururus chinensis, 600 parts of Honeysuckle flower, 900 parts of folium isatidis, 500 parts of the rhizoma bolbostemmae, 150 parts of climbing groundsel, bigleafbeautyberry root or leaf 150 Part, 600 parts of kaempferia galanga, 600 parts of the fruit of glossy privet, 600 parts of small-leaf bonesetting, 300 parts of Rhizoma Gastrodiae, 700 parts of radix semiaquilegiae, 800 parts of rainbow conk, scouring rush 300 Part, 500 parts of cortex acanthopanacis, 300 parts of Orostachys fimbriatus, 500 parts of great burdock achene, 300 parts of China rose, 500 parts of dark plum, 150 parts of fructus polygoni orientalis, radix polygonati officinalis 600 parts and 900 parts of lysiontus pauciflorus.
Most preferably, the medicament can be tablet, dispersible tablet, powder or capsule.
Ten liang of leaves
Medicine elementary source：Complete stool for Rhamnaceae Genus Chaydaia plant Herba Rednerved Chaydaiae.
Former plant：Herba Rednerved Chaydaiae Chaydaia rubrinervis (Levl.) C.Y.Wu ex Y.L.Chen [C.crenulata Hand.Mazz.]
Fourth last of the ten Heavenly stems grass Classification system Zornia gibbosa Spanoghe
The medicament for the treatment of rhinitis of the present invention have it is at low cost, prepare easily, toxic side effect is small, spy of significant curative effect Point.
Specific embodiment
Embodiment 1：
Weigh 80 grams of the flower bud of lily magnolia, 80 grams of the root of Dahurain angelica, 80 grams of Rhizoma Atractylodis Macrocephalae, 30 grams of asarum, 80 grams of wrinkled giant hyssop, 150 grams of Radix Astragali, 60 grams of cicada slough, 50 grams of peppermint, 60 grams windproof, 110 grams of campanulaceae, 110 grams of grass-leaved sweetflag, 50 grams of the achene of Siberian cocklebur, 110 grams of honeysuckle, 110 grams of coix seed, Fu 120 grams of Siberian cocklebur, 110 grams of Fructus Forsythiae, 120 grams of lily, 110 grams of Rhizoma Chuanxiong, 110 grams of root of Chinese trichosanthes, 120 grams of dried orange peel, 110 grams of Fructus Aurantii, hydrochloric acid match 1.5 grams of 1.2 grams of pyridine in heptan and chlorphenamine maleate are crushed, are sieved with 100 mesh sieve, and are uniformly mixed, are then dispensed into 1000 capsule shells In to get capsule of the present invention.
Embodiment 2：
Weigh 80 grams of the flower bud of lily magnolia, 80 grams of the root of Dahurain angelica, 80 grams of Rhizoma Atractylodis Macrocephalae, 30 grams of asarum, 80 grams of wrinkled giant hyssop, 150 grams of Radix Astragali, 60 grams of cicada slough, 50 grams of peppermint, 60 grams windproof, 110 grams of campanulaceae, 110 grams of grass-leaved sweetflag, 50 grams of the achene of Siberian cocklebur, 110 grams of honeysuckle, 110 grams of coix seed, Fu 120 grams of Siberian cocklebur, 110 grams of Fructus Forsythiae, 120 grams of lily, 110 grams of Rhizoma Chuanxiong, 110 grams of root of Chinese trichosanthes, 120 grams of dried orange peel, 110 grams of Fructus Aurantii, hydrochloric acid match 1.2 grams of pyridine in heptan, 1.5 grams, ten liang 150 grams of leaves of chlorphenamine maleate, the fourth last of the ten Heavenly stems grass 150 grams, 150 grams of annual fleabane herb, 900 grams of garlic, 300 grams of aspongopus, 500 grams of rhizoma homalonemae, 900 grams of sargentodoxa cuneata, 600 grams of sword bean, 150 grams of saururus chinensis, 600 grams of Honeysuckle flower, folium isatidis 900 grams, 500 grams of the rhizoma bolbostemmae, 150 grams of climbing groundsel, 150 grams of bigleafbeautyberry root or leaf, 600 grams of kaempferia galanga, 600 grams of the fruit of glossy privet, small-leaf bonesetting 600 Gram, 300 grams of Rhizoma Gastrodiae, 700 grams of radix semiaquilegiae, 800 grams of rainbow conk, 300 grams of scouring rush, 500 grams of cortex acanthopanacis, 300 grams of Orostachys fimbriatus, great burdock achene 500 Gram, 300 grams of China rose, 500 grams of dark plum, 150 grams of fructus polygoni orientalis, 900 grams of 600 grams of radix polygonati officinalis and lysiontus pauciflorus, crush, sieve with 100 mesh sieve, It is uniformly mixed, is then dispensed into 1000 capsule shells to get capsule of the present invention.
Experimental example
100 diagnosing patient standard references《Diseases of eye, ear, nose and throat section Disease Diagnosis Standard》(Bei Zhengping, Shu Huai, all beam ear noses Laryngeal disease diagnostic criteria [M] Beijing:Science Press, 2001；Allergia nose's inflammation diagnostic criteria in 295-296)；The traditional Chinese medical science Diagnose reference《Tcm clinical practice disease Standardization of diagnosis and curative effect》(State Administration of Traditional Chinese Medicine Chinese medical diseases Standardization of diagnosis and curative effect [S] south Capital:Publishing house of Nanjing University, 1994；124), clinical symptoms with rhiocnesmus, nasal obstruction, stream clear water tears, to seasonal variations sensitivity.It is clinical Bilateral meatus nasi inferior mucoid object, middle concha nasalis inferior mucosal pallor oedema are shown in sign inspection, to vasoconstrictor sensitivity.There to be typical case Symptom is simultaneously divided into two groups (each 50) through 100 patients that training inspection is made a definite diagnosis, wherein first group of man 25, female 25, age It is 18-60 Sui, 36.5 years old average；- 1 year March of the course of disease.Second group of man 25, female 25 are age 17-61 Sui, 37.2 years old average；Disease Journey -1 year 2 months.Two groups gender, the age, the course of disease, etc. the (P that compares that there was no significant difference>0.05) it, is comparable.
First group of patient takes orally the capsule of the preparation of embodiment 1,1 time a day, 1 oral every time, continuous treatment 7 days.
Second group of patient takes orally the capsule of the preparation of embodiment 2,1 time a day, 1 oral every time, continuous treatment 7 days.
Criterion of therapeutical effect
Reference《Clinical disease diagnosis is according to healing improvement standard》With《Tcm clinical practice disease Standardization of diagnosis and curative effect》(in country Drug Administration Chinese medical diseases Standardization of diagnosis and curative effect [S] Nanjing:Publishing house of Nanjing University, 1994；124) curative effect is evaluated.It is clinical It cures：Symptom all disappears, and does not recur within continuous 1 year or more；It is effective:Symptom all disappears, and is recurred, but symptom significantly subtracts in 1 year Gently；Effectively:The symptoms were significantly improved, is recurred again in half a year；In vain:Symptom, which is not improved or is discontinued, to be recurred
Treatment results
In first group of patient, clinical cure 20, effective 13, effective 17.In second group of patient, clinical cure 42 Example, effective 8.Do not occur serious adverse reaction in observation, blood, urine, stool routine and the liver kidney function of two groups of patients after treatment end It can check and be showed no exception.

Claims (4)

1. a kind of medicament for treating rhinitis, it is characterised in that it includes the substance of following weight proportioning：50-120 parts of the flower bud of lily magnolia, the root of Dahurain angelica 50-120 parts, 50-120 parts of Rhizoma Atractylodis Macrocephalae, 20-50 parts of asarum, 50-120 parts of wrinkled giant hyssop, 100-200 parts of Radix Astragali, 50-80 parts of cicada slough, peppermint 20-70 parts, 50-70 parts windproof, 100-120 parts of campanulaceae, 100-120 parts of grass-leaved sweetflag, 30-70 parts of the achene of Siberian cocklebur, honeysuckle 100-120 Part, 100-120 parts of coix seed, 100-150 parts of Poria cocos, 100-120 parts of Fructus Forsythiae, 100-150 parts of lily, 100-120 parts of Rhizoma Chuanxiong, day 100-120 parts of pollen, 100-150 parts of dried orange peel, 100-120 parts of Fructus Aurantii, 1.0-1.6 parts of anarexol and chlorphenamine maleate 1.2-2.0 part.
2. the medicament for the treatment of rhinitis according to claim 1, it is characterised in that it includes the substance of following weight proportioning：It is pungent 80 parts smooth, 80 parts of the root of Dahurain angelica, 80 parts of Rhizoma Atractylodis Macrocephalae, 30 parts of asarum, 80 parts of wrinkled giant hyssop, 150 parts of Radix Astragali, 60 parts of cicada slough, 50 parts of peppermint, windproof 60 Part, 110 parts of campanulaceae, 110 parts of grass-leaved sweetflag, 50 parts of the achene of Siberian cocklebur, 110 parts of honeysuckle, 110 parts of coix seed, 120 parts of Poria cocos, Fructus Forsythiae 110 Part, 120 parts of lily, 110 parts of Rhizoma Chuanxiong, 110 parts of root of Chinese trichosanthes, 120 parts of dried orange peel, 110 parts of Fructus Aurantii, 1.2 parts of anarexol and Malaysia Sour 1.5 parts of chlorphenamine.
3. the medicament for the treatment of rhinitis according to claim 1 or 2, it is characterised in that also include the object of following weight proportioning Matter：Ten liang of 150 parts of leaves, 150 parts of fourth last of the ten Heavenly stems grass, 150 parts of annual fleabane herb, 900 parts of garlic, 300 parts of aspongopus, 500 parts of rhizoma homalonemae, big blood 900 parts of rattan, 600 parts of sword bean, 150 parts of saururus chinensis, 600 parts of Honeysuckle flower, 900 parts of folium isatidis, 500 parts of the rhizoma bolbostemmae, climbing groundsel 150 Part, 150 parts of bigleafbeautyberry root or leaf, 600 parts of kaempferia galanga, 600 parts of the fruit of glossy privet, 600 parts of small-leaf bonesetting, 300 parts of Rhizoma Gastrodiae, 700 parts of radix semiaquilegiae, rainbow conk 800 parts, it is 300 parts of scouring rush, 500 parts of cortex acanthopanacis, 300 parts of Orostachys fimbriatus, 500 parts of great burdock achene, 300 parts of China rose, 500 parts of dark plum, bright pink 900 parts of 150 parts of beggar, 600 parts of radix polygonati officinalis and lysiontus pauciflorus.
4. the medicament for the treatment of rhinitis according to any one of claim 1 to 3, which is characterized in that the medicament can be Tablet, dispersible tablet, powder or capsule.
CN201611210771.9A 2016-12-24 2016-12-24 A kind of medicament for treating rhinitis Pending CN108236681A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103877440A (en) * 2014-04-09 2014-06-25 樊万军 Medicine for treating rhinitis

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103877440A (en) * 2014-04-09 2014-06-25 樊万军 Medicine for treating rhinitis

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