CN108210984A - A kind of diaper for detecting calcium constituent and preparation method thereof - Google Patents
A kind of diaper for detecting calcium constituent and preparation method thereof Download PDFInfo
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- CN108210984A CN108210984A CN201810088568.1A CN201810088568A CN108210984A CN 108210984 A CN108210984 A CN 108210984A CN 201810088568 A CN201810088568 A CN 201810088568A CN 108210984 A CN108210984 A CN 108210984A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/56—Wetness-indicators or colourants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/20—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/24—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N2021/775—Indicator and selective membrane
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Abstract
The invention discloses a kind of diapers for detecting calcium constituent and preparation method thereof, belong to body trace element detection technique field.Coated with urine present gum on the counterdie inner surface of the diaper of the present invention；Urine present gum is prepared by the constant volume agent of 150 parts by weight of biological adhesion agent and 125 parts by weight of the biological buffer of 5 parts by weight, 15 parts by weight, the activating agent of 50 parts by weight, 100 parts by weight, the anti-interference agent of 3 parts by weight, 8 parts by weight, the complexant of 2 parts by weight, 6 parts by weight, the color developing agent of 0.1 parts by weight, 3 parts by weight, 5 parts by weight, 10 parts by weight.The diaper of the present invention can be detected the calcium constituent in urine, and detection method is simple and practicable, and of low cost, and detection speed is fast, may occur in which that color developing effect, result are accurate within 15 seconds.Diaper of the present invention is suitable for detection human calcium's element information.
Description
Technical field
The present invention relates to a kind of diapers for detecting calcium constituent and preparation method thereof, belong to body trace element detection technique
Field.
Background technology
Human body is an organic life entity, during all vital movements, needs the participation of various substances, this
The type and quantity of a little substances and the element composition of earth surface are basically identical.At present in the human body that can measure it is micro- about
There are more than 20 to plant, calcium constituent is the most one kind of people's in-vivo content.Calcium constituent enjoys the title of " biological element ", it is participated in human body
Various physiological functions and metabolic process influence the activity of each organ-tissue.Such as：Calcium constituent is more than 200 kinds of enzyme in human body
Activator；Calcium constituent can carry out hormone control in human body；Calcium constituent can promote the blood clotting on wound；Calcium member
Element can adjust the rhythm of the heart, reduce cardiovascular permeability, control inflammation and oedema；The soda acid that calcium constituent can remain internal is put down
Weighing apparatus；The contraction movement of muscle and the release of neurotransmission are also required for the participation of calcium constituent.
In daily life, if the intake of calcium is insufficient, human body just will appear the overdraw of physiological calcium, cause under calcium level
Drop.Usually there is bad, hypoimmunity of sleep terror fright at night, the morbid night crying of babies, agitation, night sweat, apocleisis, rickets, skeleton development etc. in children's calcium deficiency
Symptom.Teenager's calcium deficiency usually show leg it is soft, knot, energy do not concentrate, agitation, partial eclipse, decayed tooth, easy allergy, tooth development
The symptoms such as bad.Between twenty and fifty calcium deficiency usually shows the symptoms such as weak, cramp, easy allergy, easy catching a cold.Pregnant and lying-in women's calcium deficiency usually table
It is now the symptoms such as arthralgia, crus spasm, edema, the hypertension of pregnancy.It is soft that person in middle and old age's calcium deficiency often appears as osteoporosis, sclerotin
Change, hypertension, cardiovascular and cerebrovascular diseases, calculus etc..If the intake of calcium can at most influence other trace element absorption, simultaneously
Increase the danger for suffering from kidney stone.For children, the intake of excessive calcium constituent can make it is skeletogenous be closed in advance, influence body
Development.
For baby, calcium is a kind of indispensable important substance in developmental process, since infant's skeleton development is fast
Speed needs more calcium, slightly not note that the phenomenon that not will appear calcium deficiency or excessive calcium intake infant.During baby's calcium deficiency,
It will appear soft skull, the bald, pigeon breast of pillow, rickets, " O " shape leg or X-shaped leg.Calcium intake is excessive, can accelerate infant's fontanel
The symptoms such as closure, higher urinary calcium ahead of time.Therefore the calcium constituent in real time monitoring infant urine is one of guarantee infantile health important
Means.In daily life most people can only by by the urine of baby send to hospital or specialized agency detection just will appreciate that baby
Whether internal calcium element content is normal, and clinically common calcium detection method has spectrophotometry, complexometry at present
Method, atomic absorption method etc., these methods needs operate special instrument and equipment by professional and are detected, and therefore, go to hospital
Or special testing agency's testing cost is higher, if it is desired to which long-term monitoring is also a no small expense, and is detected every time
Be required for band baby go in person hospital or testing agency or be collect infant urine inspection, this mode is time-consuming and laborious to take
Money, it is extremely inconvenient.Diaper is the indispensable indispensable daily necessities of current infant.The dosage of the daily diaper of infant can
To reach 7-8 pieces.Therefore the content trend of calcium constituent in infants is detected by diaper, was not only facilitated, but also can be baby
Parents of infants provides referential data, is a kind of very easy and effective method.
Urine present gum is that a kind of hot melt adhesive is acted with combining to substance of the pH value with Color-sensitive characteristic
's.It urinates present gum and one side of the counterdie towards sandwich layer is coated in the form of lines, when urine soaks sandwich layer, be transmitted to the table of urine present gum
Face makes its pH value change, and variation is generated so as to cause color, reaches the aobvious vision monitoring effect of urine, is usually used in diaper
The wet display function of urine.The urine present gum of calcium constituent can be detected by being had no in existing urine present gum.
The urine present gum for detecting calcium constituent is introduced into the daily necessities diaper of infant, can realize infants
The implementation of interior calcium element content monitors, and in existing diaper, does not find the diaper of the urine present gum containing detection calcium constituent.
Invention content
To solve the problems, such as that existing urine present gum does not have detection calcium constituent, the present invention provides a kind of detection calcium constituents
Diaper and preparation method thereof, the technical solution of use are as follows：
The purpose of the present invention is to provide a kind of diaper for detecting calcium constituent, applied on the counterdie inner surface of the diaper
There is urine present gum；The urine present gum is biological buffer, the activity of -100 parts by weight of 50 parts by weight by -15 parts by weight of 5 parts by weight
Agent, the colour developing of the anti-interference agent of -8 parts by weight of 3 parts by weight, the complexant of -6 parts by weight of 2 parts by weight, -3 parts by weight of 0.1 parts by weight
What the constant volume agent of -150 parts by weight of agent, the biological adhesion agent of -10 parts by weight of 5 parts by weight and 125 parts by weight was prepared.
Preferably, the biological buffer is the combination of any one or more in arginine, lysine and histidine.
Preferably, the activating agent is made of polyethylene glycol and polyvinylpyrrolidone, wherein polyethylene glycol
Mass ratio with polyvinylpyrrolidone is 1:3.
Preferably, the anti-interference agent is by citric acid, tartaric acid and acetylacetone,2,4-pentanedione composition, wherein citric acid, tartaric acid and
The mass ratio of acetylacetone,2,4-pentanedione is 1:1:1.
Preferably, the complexant is tetramethyl-ring pentadiene.
Preferably, the color developing agent is erichrome blue black R, azo sulphur III or calred.
Preferably, the biological adhesion agent is aerosil.Especially biogas aerosil.Institute of the present invention
The biogas aerosil stated is existing product, can be obtained by buying.
Preferably, the constant volume agent is made of deionized water and absolute ethyl alcohol, wherein the quality of ionized water and absolute ethyl alcohol
Than being 1:1.
As the present invention most preferably scheme, the urine present gum be arginine by 10 parts by weight, 100 parts by weight activity
Agent, the anti-interference agent of 7.5 parts by weight, the tetramethyl-ring pentadiene of 4 parts by weight, the erichrome blue black Rs of 1.5 parts by weight, 10 parts by weight
What the constant volume agent of aerosil and 140 parts by weight was prepared；Wherein：Activating agent is by polyethylene glycol and polyethylene pyrrole
Pyrrolidone forms, and wherein the mass ratio of polyethylene glycol and polyvinylpyrrolidone is 1:3；Anti-interference agent is by citric acid, wine
The mass ratio of stone acid and acetylacetone,2,4-pentanedione composition, wherein citric acid, tartaric acid and acetylacetone,2,4-pentanedione is 1:1:1；Constant volume agent is by deionization
Water and absolute ethyl alcohol composition, the wherein mass ratio of ionized water and absolute ethyl alcohol are 1:1.
Preferably, the urine present gum is prepared in accordance with the following steps：
1) by the biological buffer of -15 parts by weight of 5 parts by weight, the activating agent of -100 parts by weight of 50 parts by weight, 3 parts by weight -8
The color developing agent mixing of -3 parts by weight of the anti-interference agent of parts by weight, the complexant of -6 parts by weight of 2 parts by weight and 0.1 parts by weight；
2) the constant volume agent of -150 parts by weight of 125 parts by weight and then into the mixture that step 1) obtains is added in, and 30
DEG C~35 DEG C under conditions of be mixed；
3) the biological adhesion agent of -10 parts by weight of 5 parts by weight is added in after the mixture cooling obtained step 2), is carried out again
Stirring obtains urine present gum.
The present invention also provides a kind of preparation method of above-mentioned diaper, calcium is detected urine present gum by this method using knife coating
It is compound coated in the counterdie and water suction cotton progress lamination that on counterdie inner surface, then will pass through drying process, then lamination is answered
It closes film to be combined with water absorption factor and non-woven fabrics, is finally shaped with hot melt structure glue sticking, diaper is made；The diaper be by
It is prepared according to following steps；
1) urine present gum is scratched on counterdie surface, 5s-10s is dried at 40 DEG C -45 DEG C；
2) it is counterdie and water suction cotton progress lamination is compound, then lamination composite membrane and water absorption factor and non-woven fabrics are mutually tied
It closes；
3) lamination composite membrane, water absorption factor layer and non-woven fabrics are bonded with hot melt structure adhensive and shaped, diaper is made.
Preferably, which prepares in accordance with the following steps；
1) by the biological buffer of -15 parts by weight of 5 parts by weight, the activating agent of -100 parts by weight of 50 parts by weight, 3 parts by weight -8
The color developing agent mixing of -3 parts by weight of the anti-interference agent of parts by weight, the complexant of -6 parts by weight of 2 parts by weight and 0.1 parts by weight；
2) the constant volume agent of -150 parts by weight of 125 parts by weight and then into the mixture that step 1) obtains is added in, and 30
DEG C~35 DEG C under conditions of be mixed；
3) the biological adhesion agent of -10 parts by weight of 5 parts by weight is added in after the mixture cooling obtained step 2), is carried out again
Stirring obtains urine present gum；
4) the urine present gum for obtaining step 3) is scratched on counterdie surface, and 5s-10s is dried at 40 DEG C -45 DEG C；
5) it is counterdie and water suction cotton progress lamination is compound, then lamination composite membrane and water absorption factor and non-woven fabrics are mutually tied
It closes；
6) lamination composite membrane, water absorption factor layer and non-woven fabrics are bonded with hot melt structure adhensive and shaped, diaper is made.
Further, the counterdie includes polythene PE film and hydrophobic nonwoven.
Further, the method for the drying is heated-air drying or truck dryer.
In the method for the present invention constant volume agent need under conditions of 30 DEG C~35 DEG C with biological buffer, activating agent, anti-interference
Agent, complexant and color developing agent mixing, can accelerate the dissolving of reagent, while reduce the volatilization of ethyl alcohol under the temperature condition.
The present invention detection calcium constituent urine present gum by biological buffer, activating agent, anti-interference agent, complexant, color developing agent,
Biological adhesion agent and constant volume agent composition, wherein：
Biological buffer can select one or more combinations in arginine, lysine and histidine, the buffer
It can make the pH value of urine present gum not less than 7.5, therefore biological buffer main function is to provide a kind of reaction environment of alkalinity, and
And arginine, lysine and histidine are safe and non-toxic；
Activating agent is made of polyethylene glycol and polyvinylpyrrolidone, and polyethylene glycol and polyvinylpyrrolidine
The mass ratio of ketone is 1:3, the main function of polyethylene glycol and polyvinylpyrrolidone, which is to provide divergent function and extends, to be made
With the time so that colloid reacts abundant with urine；
Anti-interference agent is made of citric acid, tartaric acid and acetylacetone,2,4-pentanedione, the quality of citric acid, tartaric acid and acetylacetone,2,4-pentanedione
Than being 1:1:1, anti-interference agent of the invention mainly uses hard ligand and organic synthesis intermediate, provides the Gao Xuan of calcium constituent
Sexual function is selected, reduces the influence factor of other elements in urine, improves the accuracy of test result；
Complexant uses tetramethyl-ring pentadiene, has larger steric hindrance and stronger electronic capability, avoids
Complex easily occur it is neat poly and poly and the characteristics of insoluble in usual vehicle, can be further improved using tetramethyl-ring pentadiene
The stability of complex；
The main function used of being to provide colour developing of color developing agent, color developing agent can be shown after being combined with the calcium constituent in urine
Colour response.Due to present invention employs anti-interference agent and complexant, thus other elements in urine on color developing agent without influence, because
Erichrome blue black R, azo sulphur III or calred may be used in this color developing agent.
Biological adhesion agent be aerosil, especially biogas aerosil (safer), biological adhesion agent
Main function is the mobile performance for reducing solution, improves the adhesion property of urine present gum and counterdie inner surface；
Constant volume agent is made of deionized water and absolute ethyl alcohol, and the mass ratio of the two is 1:1, constant volume agent main function is dilution
Dissolving.
Biological buffer provides alkaline test environment for urine in the present invention, activating agent increase urine dispersibility and
Action time, anti-interference agent be complexed with metal ion as calcium phase, such as magnesium ion, eliminate a large amount of anti-interference element.
Complexant then according to stronger electronic capability, solve in test process occur complex oligomerisation or it is insoluble the phenomenon that.Colour developing
Mainly with calcium constituent chromogenic reaction occurs for agent, judges calcium content trend.Aerosil mainly increases toughness and hydrophilic viscous
Attached property.
The urine present gum of the present invention can realize qualitative detection, can be judged in the affiliated person's body of urine according to the variation of color
The content of calcium constituent whether lack or whether exceeded.The priming color of the urine present gum of the present invention is ecru, is being actually used
Urine present gum with urine is contacted 15 seconds in the process, then observes color change, if urine present gum is constant after being contacted with urine 15 seconds
Color shows calcium deficiency in faint yellow or display yellow green or the light blue expression user's body of display, represents to use if colour developing is blue
Calcium content is normal in person's body, if colour developing aubergine represents excessive calcium level in user's body.The urine present gum of the present invention can be with
Color shown by after touching urine present gum according to the urine of different calcium contents establishes database (big data), by color and calcium
Content establishes correspondence, and user only needs the photo after colour developing being uploaded to backstage by mobile phone terminal, from the background by counting greatly
The substantially content of calcium is analyzed according to the comparison of (database) combination algorithm.
Advantageous effect of the present invention：
1st, the present invention provides one kind for the first time can detect calcium constituent urine present gum, be judged by the variation of the urine present gum color
Whether the content for whether lacking calcium constituent and the calcium constituent in user's body in user's body is exceeded, present invention urine present gum detection
Urine can easily obtain the information of calcium constituent in user's body, can find that calcium constituent is abnormal in user's body in time, energy
Enough treatments in time.
2nd, urine present gum is introduced into diaper counterdie structure (on counterdie inner surface) by the present invention, by means of urinating the viscous of present gum
Performance and calcium detectability are tied, increases the micro- test function of diaper so that diaper has the survey of trace element
Function is tried, increases the function value of wet diaper.
3rd, the application method of diaper of the present invention is simple, and user only needs to can determine whether by the color change for urinating present gum
The contents level of calcium constituent in human body, it may be convenient to obtain the information of calcium constituent in human body, which can realize in real time
The calcium in infant urine is monitored, and then understands the health status of baby in real time.
4th, present invention urine present gum and diaper are of low cost, are greatly reduced compared to professional institution (such as hospital) detection is gone
Testing cost can realize calcium constituent information in the implementation monitoring infants of low cost by using diaper of the present invention.
5th, diaper detection speed of the present invention is fast, may occur in which color developing effect, and result is accurate within 15 seconds, accuracy is high
Up to 85%.
Specific embodiment
With reference to specific embodiment, the present invention will be further described, but the present invention should not be limited by the examples.
Embodiment 1：
It present embodiments provides a kind of urine present gum for detecting calcium constituent and diaper, specific method is as follows：
1st, the urine present gum is by 5 parts by weight biological buffers (arginine), 50 parts by weight of activated doses of (poly- second of 12.5 parts by weight
+ 37.5 weight account polyethylene pyrrolidones of allyl diglycol), 3 parts by weight anti-interference agents (1 parts by weight of lemon acid+1 parts by weight winestone
Sour+1 parts by weight acetylacetone,2,4-pentanedione), 2 parts by weight complexants (tetramethyl-ring pentadiene), 0.1 parts by weight color developing agent (erichrome blue black R), 5
(+62.5 parts by weight of 62.5 parts by weight absolute alcohol are gone for parts by weight biology adhesion agent (aerosil) and 125 parts by weight constant volume agent
Ionized water) be prepared, specific preparation process is as follows：
First, by 5 parts by weight arginine, 12.5 weight account polyethylene ethylene glycol, 37.5 parts of polyvinylpyrrolidones, 1 weight
Part citric acid, 1 parts by weight tartaric acid, 1 parts by weight acetylacetone,2,4-pentanedione, 2 parts by weight tetramethyl-ring pentadienes, 0.1 parts by weight erichrome blue black R
It is put into beaker, is simply mixed with glass bar；
2nd, 62.5 parts by weight absolute alcohols and 62.5 parts by weight of deionized water are separately added into beaker, using magnetic agitation
Device is mixed at 30 DEG C -35 DEG C；
3rd, after being cooled to room temperature, 5 parts by weight aerosils is added in mixed solution, are stirred again, be configured
Into urine present gum.
2nd, urine present gum prepared by the above method is used to prepare diaper, preparation method is as follows：
1) the urine present gum for preparing the above method is scratched in counterdie surface, the heated-air drying 5s-10s at 40 DEG C -45 DEG C；
2) it is counterdie and water suction cotton progress lamination is compound, then lamination composite membrane and water absorption factor and non-woven fabrics are mutually tied
It closes；
3) lamination composite membrane, water absorption factor layer and non-woven fabrics are bonded with hot melt structure adhensive and shaped, be made to detection calcium
The diaper of element.
Truck dryer may be used instead of heated-air drying in the method dried in the present embodiment.
Embodiment 2
It present embodiments provides a kind of urine present gum for detecting calcium constituent and diaper, specific method is as follows：
1st, the urine present gum is by 15 parts by weight biological buffers (arginine), 100 parts by weight of activated doses of (poly- second of 25 parts by weight
+ 75 weight account polyethylene pyrrolidones of allyl diglycol), 8.1 parts by weight anti-interference agents (2.7 parts by weight of lemon acid+2.7 parts by weight
+ 2.7 parts by weight acetylacetone,2,4-pentanedione of tartaric acid), 6 parts by weight complexants (tetramethyl-ring pentadiene), 3 parts by weight color developing agent (eriochrome blue blacks
R), 10 parts by weight biology adhesion agents (aerosil) and 150 parts by weight constant volume agent (+75 parts by weight of 75 parts by weight absolute alcohol
Deionized water) be prepared, specific preparation process is as follows：
First, by 15 parts by weight arginine, 25 weight account polyethylene ethylene glycol, 75 parts of polyvinylpyrrolidones, 2.5 parts by weight
Citric acid, 2.5 parts by weight tartaric acid, 2.5 parts by weight acetylacetone,2,4-pentanediones, 6 parts by weight tetramethyl-ring pentadienes, 3 parts by weight erichrome blue black Rs
It is put into beaker, is simply mixed with glass bar；
2nd, 75 parts by weight absolute alcohols and 75 parts by weight of deionized water are separately added into beaker, are existed using magnetic stirring apparatus
It is mixed at 30 DEG C -35 DEG C；
3rd, after being cooled to room temperature, 10 parts by weight aerosils is added in mixed solution, is stirred, matches again
It is set to urine present gum.
2nd, urine present gum prepared by the above method is used to prepare diaper, preparation method is as follows：
1) the urine present gum for preparing the above method is scratched on counterdie surface, and 5s-10s are dried in 40 DEG C of -45 DEG C of bottom rollers；
2) it is counterdie and water suction cotton progress lamination is compound, then lamination composite membrane and water absorption factor and non-woven fabrics are mutually tied
It closes；
3) lamination composite membrane, water absorption factor layer and non-woven fabrics are bonded with hot melt structure adhensive and shaped, be made to detection calcium
The diaper of element.
Hot air drying may be used instead of dry truck dryer in the method dried in the present embodiment.
Embodiment 3
It present embodiments provides a kind of urine present gum for detecting calcium constituent and diaper, specific method is as follows：
1st, the urine present gum is by 10 parts by weight biological buffers (arginine), 100 parts by weight of activated doses of (poly- second of 25 parts by weight
+ 75 weight account polyethylene pyrrolidones of allyl diglycol), 7.5 parts by weight anti-interference agents (2.5 parts by weight of lemon acid+2.5 parts by weight
+ 2.5 parts by weight acetylacetone,2,4-pentanedione of tartaric acid), 4 parts by weight complexants (tetramethyl-ring pentadiene), 1.5 parts by weight color developing agent (chrome blues
Black R), 10 parts by weight biology adhesion agents (aerosil) and 140 parts by weight constant volume agent (+70 weight of 70 parts by weight absolute alcohol
Part deionized water) be prepared, specific preparation process is as follows：
First, by 10 parts by weight arginine, 25 weight account polyethylene ethylene glycol, 75 parts of polyvinylpyrrolidones, 2.5 parts by weight
Citric acid, 2.5 parts by weight tartaric acid, 2.5 parts by weight acetylacetone,2,4-pentanediones, 4 parts by weight tetramethyl-ring pentadienes, 1.5 parts by weight chrome blues
Black R is put into beaker, is simply mixed with glass bar；
2nd, 70 parts by weight absolute alcohols and 70 parts by weight of deionized water are separately added into beaker, are existed using magnetic stirring apparatus
It is mixed at 30 DEG C -35 DEG C；
3rd, after being cooled to room temperature, 10 parts by weight aerosils is added in mixed solution, is stirred, matches again
It is set to urine present gum.
2nd, urine present gum prepared by the above method is used to prepare diaper, preparation method is as follows：
1) the urine present gum for preparing the above method is scratched on counterdie surface, and 5s-10s are dried in 40 DEG C of -45 DEG C of bottom rollers；
2) it is counterdie and water suction cotton progress lamination is compound, then lamination composite membrane and water absorption factor and non-woven fabrics are mutually tied
It closes；
3) lamination composite membrane, water absorption factor layer and non-woven fabrics are bonded with hot melt structure adhensive and shaped, be made to detection calcium
The diaper of element.
Hot air drying may be used instead of dry truck dryer in the method dried in the present embodiment.
Embodiment 4
The present embodiment and embodiment 3 difference lies in：Biological buffer uses 10 parts by weight lysines.
Embodiment 5
The present embodiment and embodiment 3 difference lies in：Biological buffer uses 10 parts by weight histidines.
Embodiment 6
The present embodiment and embodiment 3 difference lies in：Color developing agent uses 2 parts by weight azo sulphurs III.Idol is found through experiments that
Color developing effect is good when nitrogen sulphur III is 2 parts by weight.
Embodiment 7
The present embodiment and embodiment 3 difference lies in：Color developing agent uses 2 parts by weight calred.It is 2 that calred, which is found through experiments that,
Color developing effect and sensitivity are good during parts by weight.
Embodiment 8
To investigate influence of the activating agent for color developing effect, by the way that following experiment is set to illustrate：
1st, control group 1：Individually using 100 weight account polyethylene ethylene glycol as activating agent, other steps and parameter are same real
Apply example 3；
2nd, control group 2：Individually using 100 weight account polyethylene pyrrolidones as activating agent, other steps and parameter are same
Embodiment 3；
3rd, experimental group 1：Using 100 parts by weight of activated doses of (+50 weight account polyethylene pyrroles of 50 weight account polyethylene ethylene glycol
Alkanone), other steps and parameter are the same as embodiment 3；
4th, experimental group 2：It is carried out according to embodiment 3；
5th, experimental group 3：Using 100 parts by weight of activated doses (:+ 25 weight account polyethylene pyrrole of 75 weight account polyethylene ethylene glycol
Pyrrolidone), other steps and parameter are the same as embodiment 3；
It is being urinated one by one on the diaper (being coated with urine present gum) that can detect calcium constituent prepared according to above-mentioned experiment packet
Present gum position is added dropwise urine and is detected, and urine present gum observes color after contacting 15 seconds with the urine of calcic.Experiment display, it is single
Solely using polyethylene glycol or polyvinylpyrrolidone as activating agent, color developing effect unobvious.And the mixed type used is lived
Property agent (polyethylene glycol+polyvinylpyrrolidone) color developing effect be substantially better than individually using polyethylene glycol or poly- second
Alkene pyrrolidone finds mixed type activating agent polyethylene second two by comparing as the control group 1 of activating agent and control group 2
The ratio of alcohol and polyvinylpyrrolidone is 1:Color developing effect is the most apparent when 3.
Illustrate that the present invention detects the effect that the diaper of calcium constituent can obtain by testing as follows：
The first, the diaper that can detect calcium constituent prepared by embodiment 1-7 is carried out to the detection of calcium constituent in urine, specifically
Method is as follows：
1st, detection method：A clinical urine is divided into 7 parts, then the urine on diaper prepared by embodiment 1-7
Urine is added dropwise in present gum position, and urine is made to be contacted with the urine present gum on diaper, and urine present gum is observed after 15 seconds are contacted with urine
Color change, according to urine present gum color change judge corresponding urine corresponding to human body in calcium content it is whether normal.
2nd, color judgment method：
The priming color for urinating present gum is ecru, and urine present gum with urine is contacted 15 seconds, then observes color change, if
Urine present gum is non-discolouring after being contacted with urine 15 seconds or display is faint yellow or shows yellow green or the light blue expression user's body of display
Interior calcium deficiency, if colour developing blue represents that calcium content is normal in user's body, if colour developing aubergine represents that calcium contains in user's body
Amount is excessive.
3rd, verification method：
The clinical urine detected in 1 is sent to hospital simultaneously and is detected.
4th, result：Diaper (urine present gum) color developing effect of embodiment 3 is best in embodiment 1-7, therefore embodiment 3 is most
Excellent embodiment.The testing result of the diaper prepared using the present invention is compared discovery with hospital's testing result：Two kinds of sides
The goodness of fit of method result is up to 100%, it can thus be appreciated that the diaper of the present invention disclosure satisfy that the daily monitoring requirements to baby.
2nd, the accuracy in detection for urinating present gum further to investigate the present invention implements 50 parts of clinical urines for the present invention
Then diaper prepared by example 3 takes the blood of the corresponding 50 experiment participants of 50 parts of clinic urines, 50 parts of clinical urines are used
It is compared with 50 blood calcium detection samples in the result of urine present gum, as a result shows：The calcium content testing result of present invention urine present gum
85% is up to the testing result goodness of fit of 50 blood calcium, i.e. the accuracy of present invention urine present gum is up to 85%.
Although the present invention is disclosed as above with preferred embodiment, it is not limited to the present invention, any to be familiar with this
The people of technology without departing from the spirit and scope of the present invention, can do various changes and modification, therefore the protection of the present invention
Range should be subject to what claims were defined.
Claims (10)
1. a kind of diaper for detecting calcium constituent, which is characterized in that coated with urine present gum on the counterdie inner surface of the diaper；
The urine present gum is by the biological buffer of -15 parts by weight of 5 parts by weight, the activating agent of -100 parts by weight of 50 parts by weight, 3 weight
Part anti-interference agent of -8 parts by weight, the complexant of -6 parts by weight of 2 parts by weight, the color developing agent of -3 parts by weight of 0.1 parts by weight, 5 weight
What the constant volume agent of -150 parts by weight of biological adhesion agent and 125 parts by weight of -10 parts by weight of part was prepared.
2. diaper according to claim 1, which is characterized in that the biological buffer is arginine, lysine and group
The combination of any one or more in propylhomoserin.
3. diaper according to claim 1, which is characterized in that the activating agent is by polyethylene glycol and polyethylene pyrrole
Pyrrolidone forms, and wherein the mass ratio of polyethylene glycol and polyvinylpyrrolidone is 1:3.
4. diaper according to claim 1, which is characterized in that the anti-interference agent is by citric acid, tartaric acid and acetyl
Acetone forms, wherein citric acid, and the mass ratio of tartaric acid and acetylacetone,2,4-pentanedione is 1:1:1.
5. diaper according to claim 1, which is characterized in that the complexant is tetramethyl-ring pentadiene.
6. diaper according to claim 1, which is characterized in that the color developing agent is erichrome blue black R, azo sulphur III or calcium
It is red.
7. diaper according to claim 1, which is characterized in that the biology adhesion agent is aerosil.
8. diaper according to claim 1, which is characterized in that the constant volume agent is by deionized water and absolute ethyl alcohol group
Into wherein the mass ratio of ionized water and absolute ethyl alcohol is 1:1.
9. diaper according to claim 1, which is characterized in that the urine present gum is prepared in accordance with the following steps：
1) by the biological buffer of -15 parts by weight of 5 parts by weight, the activating agent of -100 parts by weight of 50 parts by weight, -8 weight of 3 parts by weight
The color developing agent mixing of the anti-interference agent of part, -3 parts by weight of complexant and 0.1 parts by weight of -6 parts by weight of 2 parts by weight；
2) and then into the mixture that step 1) obtains add in the constant volume agent of -150 parts by weight of 125 parts by weight, and 30 DEG C~
It is mixed under conditions of 35 DEG C；
3) the biological adhesion agent of -10 parts by weight of 5 parts by weight is added in after the mixture cooling obtained step 2), is stirred again
It mixes, obtains urine present gum.
10. the preparation method of diaper described in a kind of claim 1, which is characterized in that the diaper is in accordance with the following steps
It prepares；
1) urine present gum is scratched on counterdie surface, 5s-10s is dried at 40 DEG C -45 DEG C；
2) it is counterdie and water suction cotton progress lamination is compound, then lamination composite membrane is combined with water absorption factor and non-woven fabrics；
3) lamination composite membrane, water absorption factor layer and non-woven fabrics are bonded with hot melt structure adhensive and shaped, diaper is made.
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| US6263102B1 (en) * | 1997-07-15 | 2001-07-17 | U.S. Philips Corporation | Color and contour signal generation |
| CN202235941U (en) * | 2011-06-30 | 2012-05-30 | 上海护理佳实业有限公司 | Incontinence pad for adults |
| CN105181689A (en) * | 2015-09-21 | 2015-12-23 | 济南大学 | Preparation method for eriochrome black T test paper for urinary calcium ions |
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