CN108210657A - A kind of Chinese medicine composition for preventing and treating lung cancer - Google Patents

Abstract

The present invention provides a kind of Chinese medicine compositions for preventing and treating lung cancer, include the raw material of following weight：1 30 parts of turnip, 10 40 parts of excrementum pteropi, 20 60 parts of myrobalan, 1 30 parts of rheum officinale, 1 30 parts of rhodiola root, 1 30 parts of Rhizoma Acori Calami, 1 30 parts of cordyceps sinensis, 0.1 15 parts of west safflower, 0.1 10 parts of long sunglo, 0.1 10 parts of Fructus Hippophae extractum, 0.1 10 parts of younghusband jerusalemsage root, 0.1 15 parts of Radix Glycyrrhizae and selected from least one of 0.1 20 parts of Chinese prickly ash, 0.1 20 parts of ganoderma lucidum, 0.1 2 parts of muscone.The present invention can effectively inhibit, eliminate tumour, improve the life quality of patient.

Description

A kind of Chinese medicine composition for preventing and treating lung cancer

Technical field：

The present invention relates to a kind of Chinese medicine preparations for treating lung tumors, belong to technical field of traditional Chinese medicines.

Background technology

At present, lung cancer is that morbidity and mortality growth is most fast, the life and health of serious threat people, lung in global range The incidence of cancer remains high, and is the highest disease of morbidity and mortality in tumour.Because lung cancer morbidity is fast, many patients are true Operation excision is unconditionally carried out after examining.And use transmitting sex therapy and chemotherapy larger to the side effect of human body, patient Generally require to suffer exquisite pain, and treat after along with body immunity decline, after treatment life quality decline the problems such as, The compliance of patient is bad.

This year, country increase the input to traditional Chinese medicine, more and more prescriptions of traditional Chinese medicine for having good efficacy for tumour It is found.For the medicine that compares, traditional Chinese medicine such as stablizes knurl stove, elongated strap knurl life span, increases body and exempt from all various aspects Epidemic disease function, the life quality for improving patient, improvement clinical condition etc. have certain advantage.

The present invention is to use Chinese medicine as raw material, according to the Chinese prescription of traditional medicine theoretical informatics, with reference to modern system Traditional Chinese medicine lozenge is made in agent technique.

Tibetanmedicine thinks that human body is made of " grand, red bar, Baconic " three big basis.The root of all diseases is all " grand, red bar, Baconic's " is unbalance and disorderly.Under normal circumstances, it is grand to occupy bone；Red bar occupy blood, sweat；Baconic, which occupy, to be removed Other positions except bone, blood, sweat, i.e. essence, muscle, fat, marrow, sperm, stool, urine etc..Tibetan medicine thinks Under normal condition, object of ingesting supports " first liquid ", first liquid nutrition blood, hemotrophic nutrition soft tissue meat, meat nutrient fat tissue, fat Fat nutrition bone tissue, osteotrophy marrow.The disorder being formed as between three of tumour causes ingested object to fail to turn to " just Liquid ", and be turned into " dislike liquid " and intravascular enters whole body and respectively organizes, and at the weak position of a certain immunity function, by grand knot Structure element shakes, hard, thin, cold, light, thick reverse action shrinks the lump built up and disappeared for hard difficulty.This lump like as blueness shoulders fruit stone Tibetan medicine is referred to as " stagnant cancer ", can be translated as " core " from literal, and i.e. modern medicine is referred to as the disease of tumour for this.

Patient's pulse condition string is thin, power is small and micro-, and the general arteries and veins up and down that controls is other than micro- show, and unobvious are hollow pulse, and ruffian knurl exists The dirty specific pulse condition unobvious at which of each internal organs but into a piece of bounce；Go out the point of present situation such as fish purpose ruffian knurl in urine Drop；Occur different color in up and down before this, be Baconic when having the position white of ruffian knurl, when yellow is red bar, is when red Blood etc.；Any part of body with ruffian knurl, at this above slightly contamination dirt.

Invention content

The present invention provides a kind of compound preparations being made of traditional herbal medicines.Said preparation can effectively inhibit patients with lung cancer The growth of tumour improves the life quality of patient.

A kind of Chinese medicine composition for treating lung cancer includes the raw material of following weight：1-30 parts of turnip, excrementum pteropi 10-40 parts, it is 20-60 parts of myrobalan, 1-30 parts of rheum officinale, 1-30 parts of rhodiola root, 1-30 parts of Rhizoma Acori Calami, 1-30 parts of cordyceps sinensis, western red 0.1-15 parts of flower, 0.1-10 parts of younghusband jerusalemsage root, 0.1-15 parts of Radix Glycyrrhizae and is selected from sunglo 0.1-10 parts long, 0.1-10 parts of Fructus Hippophae extractum At least one of 0.1-20 parts of Chinese prickly ash, 0.1-20 parts of ganoderma lucidum, 0.1-2 parts of muscone.

Further, the Chinese medicine composition includes the raw material of following weight：1-30 parts of turnip, excrementum pteropi 10- 40 parts, 20-60 parts of myrobalan, 1-30 parts of rheum officinale, 1-30 parts of rhodiola root, 1-30 parts of Rhizoma Acori Calami, 1-30 parts of cordyceps sinensis, west safflower 0.1-15 parts, sunglo 0.1-10 parts long, 0.1-10 parts of Fructus Hippophae extractum, 0.1-10 parts of younghusband jerusalemsage root, 0.1-15 parts of Radix Glycyrrhizae and selected from flower At least two in 0.1-20 parts of green pepper, 0.1-20 parts of ganoderma lucidum, 0.1-2 parts of muscone.

Further, the Chinese medicine composition includes the raw material of following weight：1-30 parts of turnip, excrementum pteropi 10- 40 parts, 20-60 parts of myrobalan, 1-30 parts of rheum officinale, 1-30 parts of rhodiola root, 1-30 parts of Rhizoma Acori Calami, 1-30 parts of cordyceps sinensis, west safflower 0.1-15 parts, sunglo 0.1-10 parts long, 0.1-10 parts of Fructus Hippophae extractum, 0.1-10 parts of younghusband jerusalemsage root, 0.1-15 parts of Radix Glycyrrhizae, Chinese prickly ash 0.1-20 Part, 0.1-20 parts of ganoderma lucidum, 0.1-2 parts of muscone.

Further, the Chinese medicine composition includes the raw material of following weight：10-20 parts of turnip, excrementum pteropi 20- 35 parts, 35-50 parts of myrobalan, 1-15 parts of rheum officinale, 1-10 parts of rhodiola root, 1-10 parts of Rhizoma Acori Calami, 1-10 parts of cordyceps sinensis, west safflower 0.1-5 parts, sunglo 0.1-5 parts long, 0.1-5 parts of Fructus Hippophae extractum, 0.1-7 parts of younghusband jerusalemsage root, 0.1-6 parts of Radix Glycyrrhizae, 0.1-5 parts of Chinese prickly ash, spirit 0.1-5 parts of sesame, 0.1-2 parts of muscone.

The present invention furthermore provides a kind of Chinese medicine composition, which includes A drugs and B drugs, preferably by A Drug and B drugs composition, wherein A drugs are made of the Chinese medicine material of following weight：1-30 parts of turnip, excrementum pteropi 10- 40 parts, 20-60 parts of myrobalan, 1-30 parts of rheum officinale, 1-30 parts of rhodiola root, 1-30 parts of Rhizoma Acori Calami, 1-30 parts of cordyceps sinensis, west safflower 0.1-15 parts, sunglo 0.1-10 parts long, 0.1-10 parts of Fructus Hippophae extractum, 0.1-10 parts of younghusband jerusalemsage root, 0.1-15 parts of Radix Glycyrrhizae, Chinese prickly ash 0.1-20 Part, 0.1-20 parts of ganoderma lucidum, 0.1-2 parts of muscone.Further preferred 10-20 parts of turnip, 20-35 parts of excrementum pteropi, myrobalan 35-50 Part, 1-15 parts of rheum officinale, 1-10 parts of rhodiola root, 1-10 parts of Rhizoma Acori Calami, 1-10 parts of cordyceps sinensis, 0.1-5 parts of west safflower, long sunglo 0.1-5 parts, it is 0.1-5 parts of Fructus Hippophae extractum, 0.1-7 parts of younghusband jerusalemsage root, 0.1-6 parts of Radix Glycyrrhizae, 0.1-5 parts of Chinese prickly ash, 0.1-5 parts of ganoderma lucidum, artificial 0.1-2 parts of Moschus.

Wherein B drugs are one or more in rhodiola root, Swertia patens, emblic, Radix Astragali, matrimony vine, preferably rhodiola root, Radix Astragali and matrimony vine or preferably Swertia patens, emblic and Radix Astragali.

It is big ministerial drug that side, which selects west safflower, myrobalan, Radix Glycyrrhizae, turnip, younghusband jerusalemsage root, rhodiola root, muscone,.Safflower be many medicines it This, controls the medicine of all heat symptom-complexs.Myrobalan has 17 effects that can control 20 attributes disease.Safflower, myrobalan share, and can promote patient's muscle power, together When king's medicine and queens and princesses' medicine is assisted to strengthen therapeutic effect.Side selects younghusband jerusalemsage root to control swollen core sore, and control tuberculosis throat and do, mild-natured.Fang Xuan Radix Glycyrrhizae is mild-natured, and change taste is cool, can all clear lung heat.Side selects rhodiola root serum lung, cough-relieving to bring down a fever, relieve pain, for treating pneumonia.Fang Xuan The effects that resuscitation with aromatics, degrading the channel, swelling and pain relieving.Younghusband jerusalemsage root, Radix Glycyrrhizae, rhodiola root, muscone all have auxiliary king's medicine in side The effect for the treatment of tuberculosis, while has both subdhing swelling and detoxicating, adjust Baconic, red bar with grand balance the effect of.Select turnip acrid flavour, property in side Temperature controls Baconic's disease, grand disease, red bar raw, treats grand disease and adjusts red bar, red bar of balance with it is grand.

Rheum officinale, Rhizoma Acori Calami, Chinese prickly ash, cordyceps sinensis, ganoderma lucidum is selected to be allowed to medicine for assistant in side.Rheum officinale, which has, rushes down toxic thermal organs heat.Rhizoma Acori Calami Effect helping digestion is dispelled grand, promotes stomach sun, and control and do not digest disease.Four medicines act all medicines in the side of drawing, and to reach lesion, simultaneously coordinating the drug actions of a prescription is made With.All medicine compatibilities to cure mainly red bar, based on red Ba Long complication, have the effect of clearing lung-heat is hot, annex and adjust red bar, is grand with training Balance between root makes just to liquefy and not given birth into each internal organs, tissue and blood, evil liquid for nutrition, reinvigoration, subdhing swelling and detoxicating.

For strengthen this prescription compages object wherein one side the effect of.Rhodiola root, Swertia patens, emblic may be selected to add in In above-mentioned prescription.Rhodiola root is cold in nature, sweet in flavor, puckery.It is distributed in lung channel.Promoting blood circulation and hemostasis, removing heat from the lung to relieve cough.Belong to the work classified under drug for invigorating blood circulation and eliminating stasis Blood emmenagogue.Swertia patens bitter is cold in nature, heat-clearing, stomach invigorating, dampness removing.Control indigestion, gastritis, jaundice, pinkeye, toothache, aphtha.It is remaining Sweet son is cool in nature, sweet in flavor, sour, puckery.Distributed in lung channel, stomach, effect clearing heat and cooling blood, food digesting stomach fortifying, cough-relieving of promoting the production of body fluid.More than three medicines can be with There is removing heat from the lung to relieve cough, food digesting stomach fortifying, cancer can be treated with ancillary drug.In clinical practice, there is part trouble The physically weak gas of person is weak, and taste is caused to be damaged, and product dyspepsia, loss of appetite affects the intake of food and nutrition, exacerbates the state of an illness. Nourishing and conditioning of this Chinese medicine composition to spleen, stomach can be enhanced by adding in these drugs, treated taste lesion, can be improved digestion Road function, whets the appetite, and improves nutrition intake, increases the ability that body itself resists the disease.

Likewise, to strengthen therapeutic effect of this prescription to lung cancer, can also increase including Radix Glycyrrhizae, Radix Astragali, matrimony vine in prescription Son.Said medicine has one of invigorating the spleen, qi-regulating or antitussive action.Promote object confession of ingesting during said medicine invigorating the spleen qi-regulating Foster " first liquid " transports parts of body to and does not change evil liquid.

On the other hand, with Chinese medicine composition provided by the invention, optionally addition is suitable pharmaceutically acceptable auxiliary Material, can prepare the Chinese medicine preparation that can adjust immune system, and method can be the Chinese medicine preparation production method of any conventional, Produce any conventional dosage form.In view of the compliance and drug effect of patient, the preparation is preferably peroral dosage form, is more preferably dissipated Agent, capsule or oral liquid, more preferably powder, oral liquid, most preferably powder.

The method of preparation can be：

1）Each raw material through choose it is miscellaneous after, weigh, grouping put well it is spare；

2）Each group raw material segment, pulverizes respectively, crosses No. 2 standard screens；

3）Powder is mixed to get the active constituents of medicine composition；

4）By 3）Obtained active ingredient compositions, by standard preparation process, different according to made dosage form add pharmaceutic adjuvants, It is processed and preparation is made.

Such as, it will thus provide the Chinese medicine composition method that is prepared into powder be：The Chinese medicine composition of offer, Jiang Geyuan are provided The segment of material medicine is pulverized, and mixing is up to powder.

For another example the Chinese medicine composition provided is prepared into the method for oral liquid：The composition provided is decocted through water, it After concentrate decocting liquid, then add pharmaceutically acceptable corrigent, odor mask, diluent, such as sucrose, refined honey are arranged in pairs or groups therewith, Oral liquid is made, it is filling into bottle after sterilized.How to be decocted, it then follows the general guide principle and customary means of this field, Such as needed in prescription addition nutmeg, then decoct when, nutmeg should afterwards under.

For another example the Chinese medicine composition provided is prepared into the method for buccal tablet：By the Chinese medicine composition powder provided with Prepare the suitable additive of tablet of buccal tablet, such as mannitol, magnesium stearate, dextrin, mixing granulation, whole grain, tabletting to obtain the final product.

In the case of no traditional Chinese medicine extraction condition, powder and buccal tablet preferably is made in the composition provided.In use, The powder or buccal tablet by dosage standard are got it filled, are placed in sublingual administration, is at least being swallowed after ten minutes, 30 points after swallowing Clock can drink water.

Preferably, composition each component dosage used in the present invention is：1-20 parts of turnip, 10-35 parts of excrementum pteropi, myrobalan 20-50 parts, it is 1-20 parts of rheum officinale, 1-20 parts of rhodiola root, 1-20 parts of Rhizoma Acori Calami, 1-20 parts of cordyceps sinensis, 0.1-10 parts of west safflower, long 0.1-8 parts of sunglo, 0.1-8 parts of Fructus Hippophae extractum, 0.1-7 parts of younghusband jerusalemsage root, 0.1-10 parts of Radix Glycyrrhizae, 0.1-15 parts of Chinese prickly ash, ganoderma lucidum 0.1-15 Part, 0.1-2 parts of muscone；

It is furthermore preferred that composition each component dosage used in the present invention is：10-20 parts of turnip, 20-35 parts of excrementum pteropi, myrobalan 35-50 parts, it is 1-15 parts of rheum officinale, 1-10 parts of rhodiola root, 1-10 parts of Rhizoma Acori Calami, 1-10 parts of cordyceps sinensis, 0.1-5 parts of west safflower, long 0.1-5 parts of sunglo, 0.1-5 parts of Fructus Hippophae extractum, 0.1-7 parts of younghusband jerusalemsage root, 0.1-6 parts of Radix Glycyrrhizae, 0.1-5 parts of Chinese prickly ash, 0.1-5 parts of ganoderma lucidum, 0.1-2 parts of muscone；

Involved in the present invention program to Chinese medicine be described as follows：

Turnip：Alias turnip, Orychophragmus violaceus, circle turnip, circle root, assorted cold dishes, people from northeast claim brassica napobrassica, kohlrabi, and people from Xinjiang claims Qamgur, Latin literary fame Brassica rapa, Brassica genus Vegetable Crops of Brassica turnip subspecies can form the biennial herb plant of fleshy root.It is loose Fleshy root is edible, and fleshy root is tender, fine and close, for stir-frying and eating, cooking.There is cultivation in Europe, Asia and America.Acrid flavour, it is warm-natured, it controls Baconic's disease, grand disease, red bar raw, preventable disease poison.

Research shows that turnip contains following chemical composition:Saponin(e, flavonoids, carbohydrate and its glycosides, alkaloids, volatilization Oil, phenols, tannin, amino acid, protein, sitosterol, hexadecane, β-daucosterol, Quercetin, n-dotriacontanol, oil The aliphatic acid such as acid, linoleic acid, erucic acid, eicosenoic acid, palmitic acid and stearic acid, butyl isothiocyanate, allyl isothiocyanate, Thio glucose glucosides etc..Turnip has effects that related with above-mentioned active ingredient.

Excrementum pteropi：Excrementum pteropi：Flying squirrel section animal trogopterus xanthipes Milne-Edwards Trogopterus xanthipes Milne-Edwards' Excrement.Sweet in flavor and slight bitter, it is sweet in flavor after change；Cool in nature, flat, for heat-clearing, body is mended in removing toxic substances.Resin, urea, uric acid containing volume and Retinoid substance.Animal experiments show that this product has inhibition platelet aggregation；Increase coronary blood flow effect and improve Microcirculation；And there are resisting stress damage, enhancing immune function, gastric acid secretion inhibiting and antioxidation.

Rhizoma Acori Calami：For aroid Rhizoma Acori Calami（Acorus calamus L）Dry rhizome, there is warm stomach, anti-inflammatory The effect of analgesic.Rhizoma Acori Calami is also known as rhizoma calami, calamus, smelly Pu, mud calamus, big calamus.Rhizoma Acori Calami complete stool containing it is a variety of effectively into Point, rhizome contains volatile oil, and main component is α-asarone, beta-Asarone in oil, and volatile oil is also contained at other positions of herb.Separately Still contain vitamin, palmitic acid, acorin fatty acid mixed and sugar.Modern pharmacology result of the test shows that Rhizoma Acori Calami has tranquilizing the mind town The effects that quiet, anticonvulsion and cooling.In addition, still there are the pharmacological actions such as solution smooth muscle spasm.

Cordyceps sinensis：Section ergot fungus cordyceps sinensis colonizes in stroma and larva corpse on Hepialidae insect larvae Complex.It is warm-natured, it is lightly seasoned.Gas is special, and mildly bitter flavor is puckery.Containing crude protein, amino acid, fat, PEARLITOL 25C, cordycepin, worm Oxalic acid, ergosterol, Cordyceps sinensis polysaccharide, alkaloid, uracil, adenine, adenosine, vitamin B12 and lot of trace member Element.Cordycepic acid and cordycepin are the main active substances of cordyceps sinensis.With bacteriostasis；Cytophagy can be improved, is enhanced Cardiovascular and human body immune function, also has the function of anticancer and anti-arrhythmia etc..

West safflower：West safflower is Iridaceae crocus plant safflower（Crocus sativus L.）Drying column cap, The crocetin contained（Crocitin）, west safflower aldehyde (safranal), crocin (Crocin) and west safflower bitter principle (Protocrocin), there is promoting blood circulation and removing blood stasis, removing pattogenic heat from the blood and toxic material from the body, resolving stagnation for tranquilization.In addition, modern technologies research shows that, west safflower has Inhibit cancer, adjust immunity, oxidation resistant function.

Long sunglo：Long sunglo is unique national medicine medicine resource, is formed by fungi and with the algae of its symbiosis steady Fixed symbiosis complex is referred to as lichens (Lichens), and main biological property is embodied by fungal component, because of symbiosis Fungi dominates in relationship, therefore lichens is divided into Lichenized fungi (lichen- on taxology formingfungi).The type of lichens is more, resists cold drought-enduring, extremely strong to the adaptability of environment, at the earth's surface with wide life Long field, other biological is difficult to the place survived (including south and north poles) lichens can growth and breeding.Slight bitter, puckery, taste after change It is bitter；It is cool.Effect is clearing heat and detoxicating.For lung heat, liver heat, arteries and veins is warm, the illnesss such as scorchingly hot.It can return according to the long sunglo secondary metabolite of document Class expects that class, the cruel class of contracting, dibenzo are muttered class, the body class that continues, three Shao classes, polysaccharide and other constituents for substitution, these substances have each The bioactivity of kind various kinds, including antibiotic, antibacterium, antiviral, anti-inflammatory, analgesia, antipyretic, antitumor, cytotoxicity, anti-good fortune It penetrates, plant growth inhibits and insect antifeedant etc..Including such as suberone, β-amyrin, cupreol (4), 2,4- dihydroxy -3, 6- dimethylbenzoate methyl esters, barbatic acid, damp room terpene, ethyl orsellinate, beta-hydroxy-viscous mould -5- alkene, oleanolic acid (10), (+)-usnic acid, methyl orsellinate and 4- methyl -2,6- 4-dihydroxy benzaldehydes.

Fructus Hippophae extractum：Take fructus hippophae（The ripening fruits of Elaeangnaceae plant sea-buckthorn Hippophae thamnoides L..）It is real It after decontamination, adds water to cook, leaching supernatant liquor, residue is decocted again with a small amount of water, and filtering merges filtrate twice, is concentrated into cream Shape.This product is dark brown brown solid or flowing soaking paste, and micro- tool gloss, solids is hard and crisp, and section is irregular.After water infiltration It is tried with hand, it can be by hand stained yellow.Gas micro-perfume, taste are extremely sour.Containing several physiological active substances.Mainly have vitamin, protein, Amino acid, acyl ammonia, flavonoids, carbohydrate, organic acid, steroid acid, aliphatic acid, lipid and trace element.Fructus Hippophae extractum have effects that with Above-mentioned active ingredient is related.

Younghusband jerusalemsage root：Root tuber for labiate younghusband jerusalemsage root.9 ~ October takes root tuber, cleans, and slice dries.It is sweet in flavor;Property It is flat, wind and heat dispersing;It is relieving cough and reducing sputum;Myogenic sore.Main anemopyretic cold;Coughing with a lot of sputum;Sore burst for a long time and does not holds back.

Radix Glycyrrhizae：Glycyrrhizic legume Glycyrrhiza uralensis Fisch., swollen fruit Radix Glycyrrhiza The drying root and rhizome of inflata Bat. or glycyrrhiza glabra Glycyrrhiza glabra L..It is mild-natured, it is sweet in flavor.Thoughts of returning home warp, Stomach, the spleen channel, lung channel.Invigorate the spleen and benefit qi, cough-relieving apophlegmatic, emergency analgesic therapy, mediation property of medicine.This product is mainly containing liquiritin, glycyrrhizic acid, sweet Careless glucin, sub- cloves olefinic oxide, glycyrrhetol, 18 а-hydroxyl enoxolone, different enoxolone, Radix Glycyrrhizae coumarin, thorn awns handle Florigen, new Licochalcone D, glycyrrhiza glabra aglycon, isolicoflavonol, triterpenoid saponin, Ingredients Such As Coumarin.Radix Glycyrrhizae in prescription With the effect of it is related with above-mentioned active ingredient.

Chinese prickly ash：The ripe pericarp of rutaceae Chinese prickly ash Zanthoxylum bungeanum Maxim..Acrid flavour, property is rough, It controls grand disease and enters the heart, the top grade medicine for train of thought of relaxing.Containing volatile oil, contain limonene, cumic alcohol, Geraniol etc. in oil.Pharmacological evaluation Show that pericarp parenteral solution has analgesic, anesthetic effect；Geraniol can cause intestine in vitro to be wriggled in a small amount, largely then be allowed to inhibit； Water decoction is to streptococcus, staphylococcus, pneumococcus, bacillus anthracis, hay bacillus, comma bacillus, paratyphosum Bacterium and green pus Bacillus has inhibiting effect.Chinese prickly ash has effects that related with above-mentioned active ingredient in prescription.

Ganoderma lucidum：Polyporaceae plant fungi purple sesame Ganoderma sinense Zhao, Xu et Zhang or Polyporaceae Fungi red sesame Gan.The fructification of derma lucidum (Ley-ss.ex Fr.) Karst..It is sweet in flavor, property and.Invigorating qi for tranquilization, only Cloperastine is breathed heavily.For having no peace of mind, palpitaition of having a sleepless night, deficiency syndrome of the lung cough and asthma, consumptive disease loses heart, do not feel like eating.Containing ergot, sterol, fungi lyase Bacterium, acidic protein, water soluble protein, amino acid, polypeptide, alkaloid and polysaccharide, triterpenoid etc..To nervous system There is sedation；Play the role of enhancing its function to angiocarpy；There are antibechic, phlegm-dispelling functions to respiratory system；It can also improve generation It thanks, enhances immune function；There is inhibiting effect to pneumococcus, alpha streptococcus, staphylococcus albus and Bacillus influenzae.Ganoderma lucidum has The effect of having, is related with above-mentioned active ingredient.Ganoderma lucidum has effects that related with above-mentioned active ingredient in prescription.

Muscone：Containing muskone, and containing muscopyridine, still 11 kinds of androstane derivatives, alcohols containing cholesteric, fat, albumen Matter, wax and inorganic salts.Experiment shows that this product has stimulating central nervous system and revival effect, can excited breathing, acceleration heartbeat, raising Blood pressure；Effect of the adrenaline to beta receptors can be increased, and have cool in nature to the increasing action of beta- catecholamines, removing toxic substances is controlled The effects that parasitosis, resuscitation with aromatics, degrading the channel, swelling and pain relieving.

Rhodiola root：The herb of crassulaceae plants rhodiola root Rhodiola roseaL..It is cold in nature, it is sweet in flavor, puckery.It is distributed in lung channel.Property It is cold, it is sweet in flavor, puckery.It is distributed in lung channel.Promoting blood circulation and hemostasis, removing heat from the lung to relieve cough.Mainly containing rhodioside, tyrosol, dendrolasin, Zang Honghua aldehyde, 17 kinds of amino acid, 21 kinds of trace elements and the ingredients such as multivitamin, volatile oil, flavones, sterol, organic acid that human body needs. Rhodiola root has effects that related with above-mentioned active ingredient in prescription.

Swertia patens：The drying herb of gentianaceae plant knurl hair Swertia patens Swertia pseudochinensis Hara.Property It is cold, bitter.Return liver warp, stomach, large intestine channel.Clearing away damp-heat, stomach invigorating.Herb contains when medicine hardship glycosides 2%~4%, gentiamarin, and erythricine is Bark of ash alkali, rough gentian anthraquinone, oleanolic acid, swertisin, homo-orientin, isovitexin, Folium daisy gentisin, when medicine xanthone, first Base works as medicine xanthone, and methyl Folium daisy gentisin, to leaf when medicine xanthone, Norbellidifodin, demethyl is as medicine Xanthones Ton ketone.Also contain chiratin, hardship is when medicine ester glycosides, amarogentin.Swertia patens have effects that related with above-mentioned active ingredient in prescription.

Emblic：(medicine is commonly used to the ripening fruits of euphorbia plant emblic Phyllan-thus emblica L. by Tibetan Material).It is cool in nature, it is sweet in flavor, sour, puckery.Distributed in lung channel, stomach.Clearing heat and cooling blood, food digesting stomach fortifying, cough-relieving of promoting the production of body fluid.Containing tannin, wherein there is grape Sugared nutgall tan glucoside, gallic acid, benzoaric acid, corilagin, terchebin, Chebulagic acid, chebulinic acid, He Zici Acid, 3,6- digalloylglucoses, dry fruit 4%-9% containing glactaric acid.Pericarp contains gallic acid, phyllemblic acid, emblic phenol.Seed contains Fixing oil about 26% contains leukotrienes 8.8%, linoleic acid 44%, 28.4 % of oleic acid, stearic acid 2.2%, palmitic acid 3.0%, Pork and beans in oily Cool sour 1% etc..Emblic has effects that related with above-mentioned active ingredient in prescription.

Radix Astragali：Legume astragalus mongolicus Astragalus membranaceus Bge. var.mongholicus (Bge.) root of Hsiao and Astragalus membranacus A.membranaceus (Fisch.) Bge..Slightly warm in nature, it is sweet in flavor.Converge to the spleen channel, lung Through.Invigorating qi for strengthening superficies, diuresis, pus draining and toxin expelling, myogenic.Mainly containing ingredients such as triterpenoid saponin, flavones and polysaccharide.Water decoction tool, which is adjusted, exempts from Epidemic disease, anti-aging and anti-stress effect.Radix Astragali has effects that related with above-mentioned active ingredient in prescription.

The fruit of Chinese wolfberry：The ripening fruits of plant of Solanaceae lycium barbarum Lycium barbarum L..It is mild-natured, it is sweet in flavor, return liver warp, Kidney channel, nourishing liver and kidney, benefiting shrewd head.Containing polysaccharide, aliphatic acid, glycine betaine, carrotene, riboflavin, niacin, amino acid, vitamin C and various trace elements etc..There is anti-fatty liver, anti-aging, improve immunity.The fruit of Chinese wolfberry has effects that in prescription It is related with above-mentioned active ingredient.

The invention has the advantages that：A kind of herbal mixture buccal tablet disclosed by the invention, can effectively inhibit, Tumour is eliminated, improves the life quality of patient.

Specific embodiment：

It is further illustrated the present invention below by way of several embodiments.It should be appreciated that cited all embodiments are to help this Field technology personnel understand and implement the present invention, not any type of any limitation of the invention.All are in base of the present invention The simple modifications carried out on plinth and adjustment and raw material therein is carried out to equivalent or equivalent replacement, and fail to generate new Substantive distinguishing features and marked improvement, it should all be within protection scope of the present invention.

1 composition prescription example of embodiment

Several example prescriptions are given below, and indicate each prescription scope of application and object.It is noted that listed prescription is not Any restriction to composition, only concrete example purposes of discussion.The card that those skilled in the art can show according to disease Shape is different, and the constitution difference of patient is adjusted prescription, these adjustment should be equally included within protection scope of the present invention.

Prescription 1

Turnip 72g, excrementum pteropi 145g, rheum officinale 7g, rhodiola root 7g, Rhizoma Acori Calami 14g, west safflower 4g,

It is myrobalan 218g, long sunglo 4g, Fructus Hippophae extractum 4g, younghusband jerusalemsage root 4g, Radix Glycyrrhizae 4g, Chinese prickly ash 4g, cordyceps sinensis 7g, ganoderma lucidum 4g, artificial Moschus 2g；

Prescription 2

Turnip 72g, excrementum pteropi 145g, rheum officinale 7g, rhodiola root 7g, Rhizoma Acori Calami 14g, west safflower 4g,

Myrobalan 218g, long sunglo 4g, Fructus Hippophae extractum 4g, younghusband jerusalemsage root 4g, Radix Glycyrrhizae 4g, cordyceps sinensis 7g, muscone 2g, ganoderma lucidum 30g；

Prescription 3

Turnip 72g, excrementum pteropi 145g, rheum officinale 7g, rhodiola root 7g, Rhizoma Acori Calami 14g, west safflower 4g,

Myrobalan 218g, long sunglo 4g, Fructus Hippophae extractum 4g, younghusband jerusalemsage root 4g, Radix Glycyrrhizae 4g, cordyceps sinensis 7g, muscone 2g；

Prescription 4

Turnip 72g, excrementum pteropi 145g, rheum officinale 7g, rhodiola root 7g, Rhizoma Acori Calami 14g, west safflower 4g,

It is myrobalan 218g, long sunglo 4g, Fructus Hippophae extractum 4g, younghusband jerusalemsage root 4g, Radix Glycyrrhizae 4g, Chinese prickly ash 4g, cordyceps sinensis 7g, ganoderma lucidum 4g, artificial Moschus 2g, rhodiola root 15g, fruit of Chinese wolfberry 10g；

Prescription 5

Turnip 72g, excrementum pteropi 145g, rheum officinale 7g, rhodiola root 7g, Rhizoma Acori Calami 14g, west safflower 4g,

It is myrobalan 218g, long sunglo 4g, Fructus Hippophae extractum 4g, younghusband jerusalemsage root 4g, Radix Glycyrrhizae 4g, Chinese prickly ash 4g, cordyceps sinensis 7g, ganoderma lucidum 4g, artificial Moschus 2g, Radix Astragali 35g, Swertia patens 8g, emblic 20g；

Prescription 6

Turnip 72g, excrementum pteropi 120g, rheum officinale 30g, rhodiola root 40g, Rhizoma Acori Calami 25g, west safflower 8g,

Myrobalan 200g, long sunglo 15g, Fructus Hippophae extractum 10g, younghusband jerusalemsage root 20g, Radix Glycyrrhizae 30g, Chinese prickly ash 4g, cordyceps sinensis 10g, ganoderma lucidum 30g, muscone 2g；

Embodiment 2

By mice lung cancer Lewis knurl pillar cells cultures, 37 DEG C, routine culture under 5% carbon dioxide, passage in average every two days is primary, To exponential phase density 3.0*10 is prepared into physiological saline⁷/ ml single cell suspensions, with 75% alcohol disinfecting animal knurl table Face and surrounding skin, aseptically remove knurl, with 0.9% sodium chloride injection with 1：1（V:V）Living cells is made in ratio It is counted as 10⁷The knurl tissue homogenate of/mL is inoculated on the right side of normal nude mice under armpit, every animal inoculation pvaccination 0.2mL, observation The growing state of knurl, treats tumor volume>100mm³When, same treatment operation carry out passage inoculation, with reach 2 generations and more than Knurl tissue homogenate operates by the same method is inoculated in oxter on the right side of formal experiment nude mice.

It is 100mm to take tumor volume³Above nude mice is grouped at random by tumor volume, every group 10, and experiment sets model pair According to group, positive controls, prescription group administration group, by 20mL/kg gastric infusions, 1 times/day, continuous 28 days.It is seen daily during experiment Examine the situation of the diet of animal, drinking-water, behavioral activity and knurl, the every 5 days length and widths and the weight of animals for measuring and recording knurl, Animal is put to death at the end of experiment, knurl is removed, weighs.

Gross tumor volume and Relative tumor proliferation rate：Using the length and width of vernier caliper measurement tumour, calculate gross tumor volume T and resist Tumor promotion evaluation index is Relative tumor proliferation rate：The standard of curative effect evaluation：T/C % >40 % are invalid；T/C %≤40% is Effectively.

It can be obtained from experimental result, by being set up with setting up blank control group and positive drug control group and the drug of the present invention Experimental group carry out contrast experiment.Number of animals of the administration group tumor control rate of the present invention more than 40% is significantly more than positive control Group and blank administration group, it was demonstrated that drug has apparent inhibiting effect to the proliferation of tumour cell.

Embodiment 2

Therapy：It is buccal, once a day, one time 4, a month as a course for the treatment of.

Curative effect judging standard：

It cures：Symptom all disappears, and 2 years and does not recur above；

It is effective：The disappearance or substantially reduced of affected area pain, CT show that affected area tumour is obviously reduced；

Effectively：Affected area pain relief, CT show that affected area tumour does not continue to increase, other positions have no new tumour；

In vain：Affected area pain is not alleviated, and tumour continues to increase or shift.

Prescription 6 uses patient：Patient Tang, man, 55 years old.Main suit：It was found that lung cancer 2 months, corpus carcinosus product is 3.0*3.8cm, Without diffusion.Patient is uncomfortable in chest, pectoralgia, cough.After receiving 6 drug treatment in June of prescription in December, 2013, Tang's state of mind is apparent It improves, uncomfortable in chest, cough symptom is reduced.In July, 2014, hospital is gone to recheck, cancer cell object diffusion, corpus carcinosus product is contracted to 3.0* 2.5cm.Patient mental is in good condition at present, and the symptoms such as uncomfortable in chest have significantly reduced, with ordinary person's life indifference.

Prescription 3 uses patient：Wu, man, 45 years old.Long-term smoking, after appearance does not stop cough, chest pain, weight loss, symptom Admission examination, Small Cell Lung Cancer, after receiving the treatment of prescription 33 months, the appetite of patient improves weight and rises, and cancer cell does not occur Transfer, after the treatment of 5 months, the area of lung tumors is contracted to 3.2*3.8cm from 3.5*4.2cm.

Treatment results：10 malign lung knurl patient's symptom after taking medicine are alleviated in various degree, and symptom can significantly change after six months It is kind, at present wherein 7 patients with knurl life span more than 3 years.

Claims (10)

1. a kind of Chinese medicine composition for preventing and treating lung cancer, which is characterized in that include the bulk pharmaceutical chemicals of following weight：It is climing 1-30 parts of cyanines, 10-40 parts of excrementum pteropi, 20-60 parts of myrobalan, 1-30 parts of rheum officinale, 1-30 parts of rhodiola root, 1-30 parts of Rhizoma Acori Calami, winter worm Grass 1-30 parts of summer, 0.1-15 parts of west safflower, sunglo 0.1-10 parts long, 0.1-10 parts of Fructus Hippophae extractum, 0.1-10 parts of younghusband jerusalemsage root, Radix Glycyrrhizae 0.1-15 parts and selected from least one of 0.1-20 parts of Chinese prickly ash, 0.1-20 parts of ganoderma lucidum, 0.1-2 parts of muscone.

2. Chinese medicine composition according to claim 1, which is characterized in that include the bulk pharmaceutical chemicals of following weight：It is climing 1-30 parts of cyanines, 10-40 parts of excrementum pteropi, 20-60 parts of myrobalan, 1-30 parts of rheum officinale, 1-30 parts of rhodiola root, 1-30 parts of Rhizoma Acori Calami, winter worm Grass 1-30 parts of summer, 0.1-15 parts of west safflower, sunglo 0.1-10 parts long, 0.1-10 parts of Fructus Hippophae extractum, 0.1-10 parts of younghusband jerusalemsage root, Radix Glycyrrhizae 0.1-15 parts and at least two in 0.1-20 parts of Chinese prickly ash, 0.1-20 parts of ganoderma lucidum, 0.1-2 parts of muscone.

3. Chinese medicine composition according to claim 1, which is characterized in that include the bulk pharmaceutical chemicals of following weight：It is climing 1-30 parts of cyanines, 10-40 parts of excrementum pteropi, 20-60 parts of myrobalan, 1-30 parts of rheum officinale, 1-30 parts of rhodiola root, 1-30 parts of Rhizoma Acori Calami, winter worm Grass 1-30 parts of summer, 0.1-15 parts of west safflower, sunglo 0.1-10 parts long, 0.1-10 parts of Fructus Hippophae extractum, 0.1-10 parts of younghusband jerusalemsage root, Radix Glycyrrhizae 0.1-15 parts, 0.1-20 parts of Chinese prickly ash, 0.1-20 parts of ganoderma lucidum, 0.1-2 parts of muscone.

4. according to the Chinese medicine composition described in claim 1-3 any one, which is characterized in that raw material further includes at least one choosing From rhodiola root, Swertia patens, emblic.

5. according to the Chinese medicine composition described in claim 1-3 any one, which is characterized in that raw material further includes at least one choosing From Radix Astragali, the fruit of Chinese wolfberry.

6. Chinese medicine composition according to claim 3, it is characterised in that bulk pharmaceutical chemicals weight consumption is：1-20 parts of turnip, five Clever fat 10-35 parts, 20-50 parts of myrobalan, 1-20 parts of rheum officinale, 1-20 parts of rhodiola root, 1-20 parts of Rhizoma Acori Calami, 1-20 parts of cordyceps sinensis, 0.1-10 parts of west safflower, sunglo 0.1-8 parts long, 0.1-8 parts of Fructus Hippophae extractum, 0.1-7 parts of younghusband jerusalemsage root, 0.1-10 parts of Radix Glycyrrhizae, Chinese prickly ash 0.1-15 parts, 0.1-15 parts of ganoderma lucidum, 0.1-2 parts of muscone.

7. Chinese medicine composition according to claim 3, it is characterised in that each bulk pharmaceutical chemicals weight consumption is：10-20 parts of turnip, 20-35 parts of excrementum pteropi, 35-50 parts of myrobalan, 1-15 parts of rheum officinale, 1-10 parts of rhodiola root, 1-10 parts of Rhizoma Acori Calami, cordyceps sinensis 1-10 Part, 0.1-5 parts of west safflower, sunglo 0.1-5 parts long, 0.1-5 parts of Fructus Hippophae extractum, 0.1-7 parts of younghusband jerusalemsage root, 0.1-6 parts of Radix Glycyrrhizae, Chinese prickly ash 0.1-5 parts, 0.1-5 parts of ganoderma lucidum, 0.1-2 parts of muscone.

A kind of 8. Chinese medicine preparation, which is characterized in that the Chinese medicine composition and pharmacy provided by claim 1-7 any one Upper acceptable auxiliary material is made.

9. a kind of health food, which is characterized in that the Chinese medicine composition that claim 1-7 any one is provided, as addition One of agent or ingredient are made.

10. the Chinese medicine composition described in claim 1-7 any one is preparing the application in treating lung-cancer medicament.