CN108186949A - Intervertebral prescription - Google Patents

Intervertebral prescription Download PDF

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Publication number
CN108186949A
CN108186949A CN201810206563.4A CN201810206563A CN108186949A CN 108186949 A CN108186949 A CN 108186949A CN 201810206563 A CN201810206563 A CN 201810206563A CN 108186949 A CN108186949 A CN 108186949A
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Prior art keywords
parts
radix
root
intervertebral
smilax
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CN201810206563.4A
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CN108186949B (en
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朱怀宇
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Chongqing Zheng Gang Traditional Chinese Medicine Department Of Orthopedics Hospital Co Ltd
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Chongqing Zheng Gang Traditional Chinese Medicine Department Of Orthopedics Hospital Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/90Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/46Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716Clematis (leather flower)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
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  • Pharmacology & Pharmacy (AREA)
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Abstract

The present invention relates to intervertebral treatment technical field of pharmaceuticals, disclose intervertebral prescription, and material composition includes aconiti preparata,radix, wild aconite root, the root of Chinese clematis, Radix Astragali, smilax, Radix Paeoniae Alba, Cortex Eucommiae and radix achyranthis bidentatae.The present invention solves the problem of traditional intervertebral medication effect is undesirable, and pharmacy efficiency is low and toxic side effect is big.

Description

Intervertebral prescription
Technical field
The present invention relates to intervertebral treatment technical field of pharmaceuticals, and in particular to intervertebral prescription.
Background technology
The protrasion of the lumbar intervertebral disci is one of relatively conventional illness, is primarily due to lumber ertebral disc each section (nucleus pulposus, fiber Ring and cartilage plate), especially nucleus pulposus, after having different degrees of degenerative change, under the action of external force factor, the fibre of interverbebral disc Ring breakage is tieed up, nucleus pulposus in rear or intraspinal tube, causes adjacent spinal nerve root to be pierced from rupture part prominent (or abjection) Swash or oppress, so as to generate flank pain, a series of clinical symptoms such as side lower limb or double lower limb numbness, pain.
Sciatica is the syndrome based on sciatic nerve pathway and distributed areas pain.Sciatica it is exhausted big The stimulation compressing and damage that majority of cases is the lesion secondary to sciatic nerve part and surrounding structure to sciatic nerve, referred to as after Send out sciatica;Minority is primary, i.e. ischiatitis.
Two above symptom two symptoms common for intervertebral disease, at present, when medical institutions face above-mentioned disease, often to suffering from Person opens some Yaotongning capsules, muscle relaxing waist strengthening ball, unblocking collaterals to treat arthritis patch etc., although these drugs can play certain treatment and make With, but these drugs are mostly the swelling and pain relieving played the role of, relaxing tendons and activating collaterals, are not very for the effect for treating intervertebral disease Ideal, as long as not only the packaging efficiency of process is relatively low, and it is also larger to take toxic side effect for a long time.
Invention content
The invention is intended to provide intervertebral prescription, pay no attention to that think of pharmacy efficiency low to solve traditional intervertebral medication effect, The problem of toxic side effect is big.
In order to achieve the above objectives, technical scheme is as follows:Intervertebral prescription, material composition include aconiti preparata,radix, system grass Crow, the root of Chinese clematis, Radix Astragali, smilax, Radix Paeoniae Alba, Cortex Eucommiae and radix achyranthis bidentatae.
The principle and advantageous effect of the technical program are:Aconiti preparata,radix, meridian distribution of property and flavor:It is pungent, bitter, heat;It is toxic.The thoughts of returning home, liver, Kidney, the spleen channel.Major function:Dispelling wind and eliminating dampness, antalgic.For wind-cold-dampness arthralgia, breast pain, chest pain with distension sensation, arthralgia, the heart Abdomen crymodynia, cold hernia are had a pain, narcotic analgesic.
Wild aconite root, nature and flavor:Acrid flavour, hardship, property heat, channel tropism:The heart, liver,kidney,spleen warp.Major function:Dispelling wind and eliminating dampness, Wen Jingzhi Bitterly, for wind-cold-dampness arthralgia, arthralgia, the cool pain of trusted subordinate, cold hernia analgesic.
The root of Chinese clematis, it is acrid flavour, salty, it is warm-natured;Enter bladder warp;Attending effectiveness:Variety identification root is used as medicine, and energy wind-damp dispelling, leads at diuresis Through, analgesia, control damp and hot chill, migraines, jaundice edema, fish-bone fishbone larynx, waist and knee legs and feet crymodynia.
Radix Astragali, sweet in flavor, slightly warm in nature;Channel tropism:Return lung, spleen, liver and kidney channel;Attending effectiveness:1. exterior deficiency spontaneous perspiration:It is chiefly used in physically weak Spontaneous perspiration caused by table is weak;2. night sweat due to yin deficiency:It can together be used with drugs for nourishing yin such as Radix Rehmanniae, Radix Ophiopogonis.3. acute nephritis edema:For yang-energy not Void oedema caused by foot, and often close and uses with tetrandra root, Poria cocos, Rhizoma Atractylodis Macrocephalae etc., side's such as Tetrandra and Astragalus Decoction.4. oedema due to chronic nephritis, Spleen kidney deficiency:Often with Radix Codonopsis, Rhizoma Atractylodis Macrocephalae, Poria cocos with use.5. yang-energy is weak:Invaginate for sore not diabrosis long, have promote diabrosis and Limitation acts on.Ulcer not penetrator long, often with pangolin, spina gleditsiae, Radix Angelicae Sinensis, Rhizoma Chuanxiong with using.6. sore diabrosis:It does not close up, has long The effect of promoting granulation and wound healing, often with honeysuckle flower, spina gleditsiae, Chinese violet etc..Fester cleans, and is equal with Radix Codonopsis, Chinese cassia tree and uses.7. syndrome of deficiency of lung qi:Cough With the passing of time, shortness of breath and tired spirit, phlegm harmony is brought up in lung is powerless for asthma.Chang Peiwu asters, coltsfoot etc., warm lung Dingchuan, the product of strong lung qi.Spleen is given birth to Phlegm, lung storage phlegm, so strong lunar with eliminating the phlegm, Radix Astragali tonifying Qi is so outstanding be apt to control the deficiency of vital energy.8. the deficiency of vital energy is weak:Lassitude hypodynamia or middle gas Sagging, rectal prolapse, the prolapse of uterus.Air making-up and spleen enlivening, often with the compatibilities such as Radix Codonopsis, Rhizoma Atractylodis Macrocephalae;Lifted for benefiting qi and raising yang it is sunken, often with Radix Codonopsis, Cimicifugae foetidae, radix bupleuri, honey-fried licorice root etc. share.
Smilax, property is sweet, light, puts down;Return liver, stomach;Attending effectiveness:1. controlling blood-head to have a headache, abscess of throat, menses are dripping etc. Women's mass formed by blood stasis;2. syphilis is controlled, gonorrhoea:Smilax and honeysuckle, shellac, madder, loguat leaf, radix aconiti agrestis (system), myrobalan, cape jasmine, RESINA LIQUIDAMBARIS FORMOSANAE, semen abutili, safflower, dianthus superbus, black cloud incense compatibility.
Radix Paeoniae Alba, acrid flavour are warm-natured;Enter lung, spleen, stomach;Attending effectiveness:Wind-dispelling, eliminating dampness are subsided a swelling, analgesic.Control headache, eyebrow rib Ostalgia, dentalgia, nasosinusitis, cold-dampness stomachache, intestines wind anal fistula, leukorrhea with reddish discharge, ulcer sores, skin itchy, mange.
Cortex Eucommiae cures mainly waist and knee, bowl spares, strengthening the essence gas, hard muscles and bones, except wet, dribbling urination of itching under the moon.Long term usage is made light of one's life by commiting suicide resistance to old.
Radix achyranthis bidentatae, picric acid are put down.Major function:Promoting blood circulation to remove blood stasis, clearing damp diuresis are clearing heat and detoxicating.Control gonorrhoea, hematuria, Fu Nvjing It closes, abdominal mass, rheumatic arthritis, tinea pedis, oedema, dysentery, malaria, diphtheria, carbuncle swells, traumatic injury.
Compatibility of the present invention meets Chinese medicine " monarch " principle, and prescription is scientific and reasonable, and each raw medicinal material effect is different But complement each other, by the collocation of aconiti preparata,radix and Radix Astragali motor Radix Paeoniae Alba etc., wind-dispelling detumescence is reached while dehumidifying and easing pain Effect, and intervertebral medicine material combination of the present invention is simple, toxic side effect is small, is suitble to protrusion of lumber intervertebral disc and sciatica patient long Phase takes.
Preferably, as an improvement, material composition component includes 1.5-3 parts of aconiti preparata,radix, 1.5-3 parts of wild aconite root, Wheeling 15-25 parts of 6-9 parts celestial, 9-30 parts of Radix Astragali, 15-60 parts of smilax, 10-20 parts of Radix Paeoniae Alba, 15-25 parts of Cortex Eucommiae and radix achyranthis bidentatae.
Preferably, as an improvement, material composition component include 1.5-2.5 parts of aconiti preparata,radix, 1.5-2.5 parts of wild aconite root, 15-20 parts of 6-8 parts of the root of Chinese clematis, 9-20 parts of Radix Astragali, 15-35 parts of smilax, 10-15 parts of Radix Paeoniae Alba, 15-20 parts of Cortex Eucommiae and radix achyranthis bidentatae.
Preferably, as an improvement, material composition component includes 1.5 parts of aconiti preparata,radix, 1.5 parts of wild aconite root, the root of Chinese clematis 6 15 parts of part, 9 parts of Radix Astragali, 15 parts of smilax, 10 parts of Radix Paeoniae Alba, 15 parts of Cortex Eucommiae and radix achyranthis bidentatae.
Preferably, as an improvement, material composition component includes 2 parts of aconiti preparata,radix, 2 parts of wild aconite root, 7 parts of the root of Chinese clematis, Huang 17 parts of 15 parts of stilbene, 20 parts of smilax, 12 parts of Radix Paeoniae Alba, 17 parts of Cortex Eucommiae and radix achyranthis bidentatae.
Preferably, as an improvement, material composition component includes 2.5 parts of aconiti preparata,radix, 2.5 parts of wild aconite root, the root of Chinese clematis 8 Part, 20 parts of Radix Astragali, 35 parts of smilax, 15 parts of Radix Paeoniae Alba, 20 parts of Cortex Eucommiae, 20 parts of radix achyranthis bidentatae.
Preferably, as an improvement, material composition component includes 3 parts of aconiti preparata,radix, 3 parts of wild aconite root, 9 parts of the root of Chinese clematis, Huang 22 parts of 25 parts of stilbene, 45 parts of smilax, 17 parts of Radix Paeoniae Alba, 22 parts of Cortex Eucommiae and radix achyranthis bidentatae.
Preferably, as an improvement, material composition component includes 3 parts of aconiti preparata,radix, 3 parts of wild aconite root, 9 parts of the root of Chinese clematis, Huang 25 parts of 30 parts of stilbene, 60 parts of smilax, 20 parts of Radix Paeoniae Alba, 25 parts of Cortex Eucommiae and radix achyranthis bidentatae.
Preferably, it as an improvement, being prepared by a kind of preparation method, the preparation method includes the following steps, (1) raw material is crushed with pulverizer;(2) aconiti preparata,radix, wild aconite root after crushing add clear water, and after impregnating 1 hour, vigorous fire boils, and Slow boiling boils 3 hours afterwards;(3) liquid in step (2), which removes slag, takes juice spare;(4) remaining drug adds clear water, impregnates 1 hour, suddenly After fire boils, aconiti preparata,radix, wild aconite root concoction are added in, slow boiling boils 1 hour, removes slag and take juice, be condensed into 600ml;It (5) will be above-mentioned dense The laggard luggage bag sealing of medicament is made in contracting liquid, and medicament can be decoction, pill, powder, spray or tablet, pack seal process Using automatic packer.
Description of the drawings
Fig. 1 is the structure diagram of automatic packaging machine in the embodiment of the present invention 1.
Specific embodiment
Below by specific embodiment, the present invention is described in further detail:
Reference numeral in Figure of description includes:Storage bin 1, inlet 2, outlet tube 3, gear ring 4, agitating shaft 5, active Gear 6, supporting rack 8, driven gear 9, transverse slat 10, scraper plate 11, U-type groove 12, conduit 13, backing roll 14, is fixed stirring blade 7 Bolt 15, nut 16, guide roller 17, Bidirectional-screw 18, bearing holder (housing, cover) 19, supporting rod 20, the first nut 21, the second nut 22, first Electric heating cutter 23, the second electric heating cutter 24, connecting rod 25, collecting box 26.
Embodiment 1:It is made of following components medicinal material, aconiti preparata,radix 1.5g, wild aconite root 1.5g, root of Chinese clematis 6g, Radix Astragali 9g, soil Fu Siberian cocklebur 15g, Radix Paeoniae Alba 10g, Cortex Eucommiae 15g and radix achyranthis bidentatae 15g.
In the present embodiment, preparation method during practical application includes the following steps:
(1) each raw material is pulverized and sieved respectively with pulverizer, and the medicinal material collection after crushing is spare;
(2) aconiti preparata,radix, the wild aconite root after crushing are added into clear water, after impregnating 1 hour, vigorous fire boils, and then slow boiling tanning 3 is small When;
(3) liquid of gained in step (2) removes slag takes juice spare, removes slag and juice process is taken to be completed using filter device, mistake Filter device is needed before use through sterilization processing;
(4) remaining drug adds clear water, impregnates 1 hour, after vigorous fire boils, adds in aconiti preparata,radix, wild aconite root concoction, slow boiling tanning It 1 hour, removes slag and takes juice, be condensed into the concentrated medicament of 600ml, remove slag and juice process is taken to be completed using filter device, filter device exists It is needed before use through sterilization processing, concentration process is completed using Rotary Evaporators;
(5) above-mentioned concentrated medicament is made the laggard luggage bag of medicament to seal, manufactured medicament can be decoction, pill, powder, Spray, tablet or other different types of medicaments are that concentrated medicament is put into progress boiling system in boiling pot when making decoction ;It makes pill and carries out general ball using general ball machine;It is that concentrated medicament is dried to make powder, and powder is made after dry;System It is that concentrated medicament is added in into solvent dilution as spray, is then fitted into spray bottle;Making tablet is after concentrated medicament is dried, Tabletting is carried out with tablet press machine;
(6) for concentrated medicament directly is carried out pack sealing, used is automatic packer, and structure is substantially as schemed Shown in 1, automatic packer, including rack and material storage mechanism, material storage mechanism is storage bin 1, and 1 top of storage bin is equipped with inlet 2, The bottom of storage bin 1 is equipped with liquid outlet, and liquid outlet is connected with outlet tube 3, rack gear is fixedly connected in the inner top wall of storage bin 1 4, the inner top wall of storage bin 1 is rotatably connected to agitating shaft 5, and agitating shaft 5 is connected with the first motor, and the top of agitating shaft 5 is coaxial Driving gear 6 is fixedly connected with, the bottom end of agitating shaft 5 is hinged with stirring blade 7, and be fixedly connected with supporting rack on agitating shaft 5 8, the one end of supporting rack 8 far from agitating shaft 5 is rotatably connected to driven gear 9, and driven gear 9 is engaged in driving gear 6 and gear ring 4 Between, transverse slat 10 is also fixedly connected on supporting rack 8, transverse slat 10 is fixedly connected with scraper plate 11, scraper plate 11 and 1 inner wall phase of storage bin It cuts;Filter mechanism is further included, filter mechanism includes the U-type groove 12 being fixedly connected in rack, and U-type groove 12 is equipped with lower liquid Mouthful, filtering gauze is equipped at lower liquid mouth, lower liquid mouth is fixedly connected with conduit 13;Supporting mechanism is further included, supporting mechanism includes two A backing roll 14 for being used to support packaging bag reel symmetrically arranged centered on conduit 13 is respectively equipped with fixation on backing roll 14 Bolt 15, the both ends of fixing bolt 15 are threaded with nut 16, two groups of guide roller groups are arranged between two backing rolls 14, are led Include three guide rollers 17 to roller group;The lower section of guide roller 17 is equipped with packaging mechanism, and packaging mechanism includes Bidirectional-screw 18, two-way Screw 18 is connected with the second motor, and 18 both ends of Bidirectional-screw are respectively connected with bearing holder (housing, cover) 19, and bearing holder (housing, cover) 19 has been fixedly connected with support Bar 20 is connected with the first nut 21 at 18 left side screw thread of Bidirectional-screw, and the first nut 21 is fixedly connected with the first electric heating and cuts Cutter 23;The second nut 22 is connected at 18 right side screw thread of Bidirectional-screw, the second nut 22 is fixedly connected with the second electric heating Cutter 24, the first heating cutter are oppositely arranged with the second heating cutter;First nut 21 and the second nut 22 rotate Connecting rod 25 is connected with, the bottom end of connecting rod 25 is rotatably connected in rack;The lower section of Bidirectional-screw 18 is equipped with the collection of upper opening Case 26.
In use, concentrated medicament obtained by above-mentioned steps (4) is placed in storage bin 1, the first motor is opened, agitating shaft 5 exists It is rotated under the drive of first motor, the rotation of agitating shaft 5 drives stirring blade 7 to rotate, to storage bin in 7 rotation process of stirring blade Concentrated medicament in 1 is stirred, and prevents concentrated medicament from precipitating, in addition, the rotation of agitating shaft 5 drives co-axial be fixedly connected Driving gear 6 rotates, while the rotation of agitating shaft 5 drives supporting rack 8 affixed therewith to rotate, and the rotation of supporting rack 8 drives driven tooth The engagement rotation between gear ring 4 and driving gear 6 of wheel 9, while scraper plate 11 is driven to rotate by transverse slat 10,11 rotation process of scraper plate In, since scraper plate 11 and 1 inner wall of storage bin are tangent, the concentrated medicament for being adhered to 1 inner wall of storage bin can be scraped, avoids concentrated medicament Waste.
The packaging bag reel of positive and negative is respectively sleeved on backing roll 14, fixing bolt 15 is passed through into backing roll 14, and twist Tight nut 16, is fixed packaging bag reel, and the free end of packaging bag is wrapped in guide roller group so that positive and negative packet Pack is oppositely arranged, and opens the second motor, and Bidirectional-screw 18 rotates forward under the drive of the second motor, and Bidirectional-screw 18, which rotates forward, to be driven First nut 21 and the second nut 22 move toward one another, i.e. the first nut 21 and the second nut 22 are close to each other, 21 He of the first nut Second nut 22 is close to each other so that and the first electric heating cutter 23 and the second electric heating cutter 24 are close to each other, when When the two offsets, heating sealing is carried out, while packaging bag is cut to packaging bag.
Concentrated medicament in storage bin 1 is flow to from liquid outlet along outlet tube 3 in U-type groove 12, the filtered yarn in U-type groove 12 After cloth filters the impurity in concentrated medicament, along conduit 13 downstream to the packaging bag sealed in, packaging bag reel concentration medicine It is rotated under the gravity of liquid so that the packaging bag for being loaded with concentrated medicament moves down, at this point, double laid-off screws are in the second motor Lower rotation is driven, the first nut 21 and the second nut 22 are again adjacent to, the first electric heating cutter 23 and the second electric heating Cutter 24 are close to each other, carry out sealing and cutting to packaging bag again.After sealing cutting, the packaging bag of concentrated medicament is filled It falls in collecting box 26 and is collected.
The present apparatus is rotated by driving gear 4 drives agitating shaft 5 to rotate, and the concentrated medicament in storage bin is stirred, Avoid the deposited phenomenon of concentrated medicament, in addition, the rotation of driving gear 4 drive driven gear 9 gear ring 4 and driving gear 6 it Between engagement rotation, while by transverse slat 10 drive scraper plate 11 rotate, in 11 rotation process of scraper plate, due to scraper plate 11 and storage bin 1 Inner wall is tangent, can scrape the concentrated medicament for being adhered to 1 inner wall of storage bin, avoids the waste of concentrated medicament.Present apparatus packaging process It is rotated by Bidirectional-screw 18 and drives the first electric heating cutter 23 and the second electric heating cutter 24 close to each other, when two When person offsets, heating sealing is carried out, while packaging bag is cut to packaging bag, by packaging bag concentrated medicament itself Gravity realizes the continuity charging of packaging bag, intervenes manually without operating personnel, packaging process high degree of automation, packaging efficiency It is high.
Embodiment 2:The present embodiment is made of with differing only in for embodiment 1 following components medicinal material, aconiti preparata,radix 2g, system grass Black 2g, root of Chinese clematis 7g, Radix Astragali 15g, smilax 20g, Radix Paeoniae Alba 12g, Cortex Eucommiae 17g and radix achyranthis bidentatae 17g.
Embodiment 3:The present embodiment is made of with differing only in for embodiment 1 following components medicinal material, aconiti preparata,radix 2.5g, system Radix aconiti agrestis 2.5g, root of Chinese clematis 8g, Radix Astragali 20g, smilax 35g, Radix Paeoniae Alba 15g, Cortex Eucommiae 20g and radix achyranthis bidentatae 20g.
Embodiment 4:The present embodiment is made of with differing only in for embodiment 1 following components medicinal material, aconiti preparata,radix 3g, system grass Black 3g, root of Chinese clematis 9g, Radix Astragali 25g, smilax 45g, Radix Paeoniae Alba 18g, Cortex Eucommiae 22g and radix achyranthis bidentatae 22g.
Embodiment 5:The present embodiment is made of with differing only in for embodiment 1 following components medicinal material, aconiti preparata,radix 3g, system grass Black 3g, root of Chinese clematis 9g, Radix Astragali 30g, smilax 60g, Radix Paeoniae Alba 20g, Cortex Eucommiae 25g and radix achyranthis bidentatae 25g.
Comparative example 1:Using the Yaotongning capsules in background technology.
Comparative example 2:Using the muscle relaxing waist strengthening ball in the technology of Beijing.
Comparative example 3:Using the common prescription for the treatment of sciatica, aconiti preparata,radix 10g, wild aconite root 10g, asarum 6g, the root of bidentate achyranthes 15g, rhizoma atractylodis 12g, root of fangji 12g, frankincense 10g, myrrh 10g, Rhizoma Chuanxiong 15g, cassia twig 12g and Radix Glycyrrhizae 6g, according to embodiment 1 Preparation method is prepared.
Blank example:Patient is not only compared using any drug therapy.
Drug obtained by embodiment and comparative example and blank example is subjected to clinical test respectively, every group of selection 20 suffers from lumbar vertebrae The patient of disk protrusion and sciatica is taken, and patient is investigated before and after taking, the basic condition of each group processing It is as shown in the table:
Every group of patient takes respectively according to each medicament described in upper table and dose, respectively record patient medication after 3,7,15, 20th, the treatment of 30 days, is as a result expressed as clinic control:Pain symptom disappears after treatment;;It is effective:Mitigate substantially after treatment Pain;Effectively:Slightly mitigate pain after treatment;In vain:Symptom without improvement or aggravates after treatment.As a result it is as follows:
As seen from the above table, embodiment 4 and optimum combination of the 5 corresponding prescription of embodiment for the present invention, take medicine in patient Obvious effective rate accounts for 50% after 15 days, and obvious effective rate is above comparative example 1, comparative example 2 and comparative example 3, illustrates intervertebral prescription of the present invention Preferable therapeutic effect is respectively provided with to protrusion of lumber intervertebral disc and sciatica, each medicinal material dosage of embodiment 4, which is respectively less than, to be implemented Each medicinal material dosage of example 5, but the therapeutic effect reached is close, and the economic input of comprehensive prescription is determined corresponding to embodiment 4 Prescription for the present invention optimal prescription.
Above-described is only the embodiment of the present invention, the common sense such as well known specific technical solution and/or characteristic in scheme It does not describe excessively herein.It should be pointed out that for those skilled in the art, before technical solution of the present invention is not departed from It puts, several modifications and improvements can also be made, these should also be considered as protection scope of the present invention, these all do not interfere with this Invent the effect and practical applicability implemented.The scope of protection required by this application should be based on the content of the claims, The records such as the specific embodiment in specification can be used for explaining the content of claim.

Claims (9)

1. intervertebral prescription, it is characterised in that:Material composition include aconiti preparata,radix, wild aconite root, the root of Chinese clematis, Radix Astragali, smilax, Radix Paeoniae Alba, Cortex Eucommiae and radix achyranthis bidentatae.
2. intervertebral prescription according to claim 1, it is characterised in that:It is made of by mass parts number scale following components, river processed 1.5-3 parts black, 1.5-3 parts of wild aconite root, 6-9 parts of the root of Chinese clematis, 9-30 parts of Radix Astragali, 15-60 parts of smilax, 10-20 parts of Radix Paeoniae Alba, Cortex Eucommiae 15-25 parts and 15-25 parts of radix achyranthis bidentatae.
3. intervertebral prescription according to claim 2, it is characterised in that:It is made of by mass parts number scale following components, river processed 1.5-2.5 parts black, 1.5-2.5 parts of wild aconite root, 6-8 parts of the root of Chinese clematis, 9-20 parts of Radix Astragali, 15-35 parts of smilax, 10-15 parts of Radix Paeoniae Alba, 15-20 parts of 15-20 parts of Cortex Eucommiae and radix achyranthis bidentatae.
4. intervertebral prescription according to claim 3, it is characterised in that:It is made of by mass parts number scale following components, river processed 1.5 parts of crow, 1.5 parts of wild aconite root, 6 parts of the root of Chinese clematis, 9 parts of Radix Astragali, 15 parts of smilax, 10 parts of Radix Paeoniae Alba, 15 parts of Cortex Eucommiae and radix achyranthis bidentatae 15 Part.
5. intervertebral prescription according to claim 3, it is characterised in that:It is made of by mass parts number scale following components, river processed 17 parts of 2 parts of crow, 2 parts of wild aconite root, 7 parts of the root of Chinese clematis, 15 parts of Radix Astragali, 20 parts of smilax, 12 parts of Radix Paeoniae Alba, 17 parts of Cortex Eucommiae and radix achyranthis bidentatae.
6. intervertebral prescription according to claim 3, it is characterised in that:It is made of by mass parts number scale following components, river processed 2.5 parts of crow, 2.5 parts of wild aconite root, 8 parts of the root of Chinese clematis, 20 parts of Radix Astragali, 35 parts of smilax, 15 parts of Radix Paeoniae Alba, 20 parts of Cortex Eucommiae and radix achyranthis bidentatae 20 Part.
7. intervertebral prescription according to claim 2, it is characterised in that:It is made of by mass parts number scale following components, river processed 22 parts of 3 parts of crow, 3 parts of wild aconite root, 9 parts of the root of Chinese clematis, 25 parts of Radix Astragali, 45 parts of smilax, 17 parts of Radix Paeoniae Alba, 22 parts of Cortex Eucommiae and radix achyranthis bidentatae.
8. intervertebral prescription according to claim 2, it is characterised in that:It is made of by mass parts number scale following components, river processed 25 parts of 3 parts of crow, 3 parts of wild aconite root, 9 parts of the root of Chinese clematis, 30 parts of Radix Astragali, 60 parts of smilax, 20 parts of Radix Paeoniae Alba, 25 parts of Cortex Eucommiae and radix achyranthis bidentatae.
9. intervertebral prescription according to any one of claims 1 to 8, it is characterised in that:Prepared by a kind of preparation method and Into the preparation method includes the following steps, (1) crushes raw material with pulverizer;(2) aconiti preparata,radix, wild aconite root after crushing add Clear water, after impregnating 1 hour, vigorous fire boils, and then slow boiling boils 3 hours;(3) liquid in step (2), which removes slag, takes juice spare; (4) remaining drug adds clear water, impregnates 1 hour, after vigorous fire boils, adds in aconiti preparata,radix, wild aconite root concoction, slow boiling is boiled 1 hour, gone Slag takes juice, is condensed into 600ml;(5) above-mentioned concentrated medicament is made the laggard luggage bag of medicament to seal, the medicament can be decoction, Pill, powder, spray or tablet, pack seal process is using automatic packer.
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