CN108186891A - A kind of red capsule formula living and preparation method thereof - Google Patents

A kind of red capsule formula living and preparation method thereof Download PDF

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Publication number
CN108186891A
CN108186891A CN201810267289.1A CN201810267289A CN108186891A CN 108186891 A CN108186891 A CN 108186891A CN 201810267289 A CN201810267289 A CN 201810267289A CN 108186891 A CN108186891 A CN 108186891A
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China
Prior art keywords
preparation
capsule
red
living
formula
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CN201810267289.1A
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Chinese (zh)
Inventor
赵丙辉
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Beijing Zhongbokang Medical Technology Co Ltd
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Beijing Zhongbokang Medical Technology Co Ltd
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Priority to CN201810267289.1A priority Critical patent/CN108186891A/en
Publication of CN108186891A publication Critical patent/CN108186891A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

A kind of red living capsule formula of the present invention and preparation method thereof, the formula by:American Ginseng (1), the fruit of Chinese wolfberry (2), prepared rehmannia root (3), puncture vine (4), Herba Epimedii (5), sealwort (6) forms, it is characterized in that, described American Ginseng (1) 150g, the fruit of Chinese wolfberry (2) 100g, prepared rehmannia root (3) 100g, puncture vine (4) 120g, Herba Epimedii (5) 50g, sealwort (6) 50g, 1000 are fabricated to by its preparation process, every weight 0.3g, the technical problem to be solved in the present invention is to provide a kind of red capsule formula living and preparation method thereof, purpose is to alleviate the fatigue that the mankind bring by work or other labour.

Description

A kind of red capsule formula living and preparation method thereof
Technical field:
The invention belongs to pharmaceutical formulation and preparing technical fields, and in particular to a kind of red capsule formula living and its preparation side Method.
Background technology:
With the changes of the times, earth-shaking variation all has occurred in the field of people's work and property, particularly intelligently Popularizing for equipment, can work, staff is caused to feel exhausted, in order to alleviate the fatigue of body, on the market whenever and wherever possible Largely can not be with the health products and drug of fatigue-relieving to having weeded out the old and bring forth the new, but these products are also multifarious, the good and the bad It is uneven in addition also have there may be side effect or according to lazyness, for me therefore have studied a red capsule formula living and its preparation Method, the product not only have the feeling of fatigue for alleviating personal body, also have the function of mitigating brain fatigue, the selection of this formula is equal For Chinese medicine, so being even more not according to lazyness and side effect.
Invention content:
The technical problem to be solved in the present invention is to provide a kind of red capsule formula living and preparation method thereof, it is therefore intended that slow The fatigue that the solution mankind bring by work or other labour.
In order to achieve the above objectives, a kind of red living capsule formula of the present invention and preparation method thereof, the formula by: American Ginseng (1), the fruit of Chinese wolfberry (2), prepared rehmannia root (3), puncture vine (4), Herba Epimedii (5), sealwort (6) composition, which is characterized in that described American Ginseng (1) 150g, the fruit of Chinese wolfberry (2) 100g, prepared rehmannia root (3) 100g, puncture vine (4) 120g, Herba Epimedii (5) 50g, sealwort (6) 50g is fabricated to 1000, every weight 0.3g by its preparation process.
In order to achieve the above objectives, a kind of red capsule formula living of the present invention and preparation method thereof, which is characterized in that will The American Ginseng (1) cleans slice, into pulverizer in fully crushed, sieve with 100 mesh sieve, obtain spare ginseng powder.
In order to achieve the above objectives, a kind of red capsule formula living of the present invention and preparation method thereof, which is characterized in that press Formula rate weighs the fruit of Chinese wolfberry (2), prepared rehmannia root (3), puncture vine (4), Herba Epimedii (5), and sealwort (6) is washed and chopped, will cut Broken mixture is placed in extractor, adds in the water of 10 times of amounts of medicinal material total weight, and under conditions of 100 DEG C of constant temperature, extraction 2 is small When, the remaining dregs of a decoction repeat to extract once, are then combined with leaching liquor twice, and will extraction according still further to aforesaid operations after extraction 2 hours After liquid stands 24 hours, clear liquid is obtained by filtration.
In order to achieve the above objectives, a kind of red capsule formula living of the present invention and preparation method thereof, which is characterized in that will Above-mentioned clear liquid filtering is concentrated under reduced pressure into concentrate (80 DEG C of temperature, the vacuum degree 0.06- that relative density is 1.20~1.25 0.09MPa)。
In order to achieve the above objectives, a kind of red capsule formula living of the present invention and preparation method thereof, which is characterized in that will The spare ginseng powder, which is added in above-mentioned concentrate, to be sufficiently mixed uniformly, through 60 DEG C of dryings, crushing, is crossed 80 mesh sieve, is obtained Products material powder.
In order to achieve the above objectives, a kind of red capsule formula living of the present invention and preparation method thereof, which is characterized in that will The products material powder fills capsule with automatic tire bagger, and capsule inner stuffing specification is 300mg/, by filled glue Capsule is polished, and obtains finished capsule product.
In order to achieve the above objectives, a kind of red capsule formula living of the present invention and preparation method thereof, which is characterized in that will The finished capsule product is transferred in plastic bottle or aluminum-plastic packaged to get to packaged red living capsule product.
In order to achieve the above objectives, a kind of red capsule formula living of the present invention and preparation method thereof, which is characterized in that will Described packaged red capsule product living, carries out 60Coradiation sterilizing, and average overall absorption amount is 4KGY, unevenness≤2, It is last to be fitted into according to the rules in box up to final red capsule finished product living.
The ingredient in a kind of red capsule formula living of the present invention and preparation method thereof, meeting national Chinese medicine specification will It asks.
Specific embodiment:
In a kind of red living capsule formula of the present invention and preparation method thereof embodiment, the formula by:The West Join (1), the fruit of Chinese wolfberry (2), prepared rehmannia root (3), puncture vine (4), Herba Epimedii (5), sealwort (6) composition, which is characterized in that described the West Join (1) 150g, the fruit of Chinese wolfberry (2) 100g, prepared rehmannia root (3) 100g, puncture vine (4) 120g, Herba Epimedii (5) 50g, sealwort (6) 50g, lead to It crosses its preparation process and is fabricated to 1000, every weight 0.3g.
It further, will be described in a kind of red capsule formula living of the present invention and preparation method thereof embodiment American Ginseng (1) clean slice, into pulverizer in fully crushed, sieve with 100 mesh sieve, obtain spare ginseng powder.
Further, in a kind of red capsule formula living of the present invention and preparation method thereof embodiment, by recipe ratio Example weighs the fruit of Chinese wolfberry (2), and prepared rehmannia root (3), puncture vine (4), Herba Epimedii (5), sealwort (6) is washed and chopped, by the mixed of chopping It closes object to be placed in extractor, adds in the water of 10 times of amounts of medicinal material total weight, under conditions of 100 DEG C of constant temperature, extract 2 hours, extraction 2 The remaining dregs of a decoction repeat to extract once, are then combined with leaching liquor twice, and leaching liquor is stood 24 according still further to aforesaid operations after hour After hour, clear liquid is obtained by filtration.
It further, will be above-mentioned clear in a kind of red capsule formula living of the present invention and preparation method thereof embodiment Liquid filtering is concentrated under reduced pressure into the concentrate (80 DEG C of temperature, vacuum degree 0.06-0.09MPa) that relative density is 1.20~1.25.
It further, will be described in a kind of red capsule formula living of the present invention and preparation method thereof embodiment Spare ginseng powder, which is added in above-mentioned concentrate, to be sufficiently mixed uniformly, through 60 DEG C of dryings, crushing, is crossed 80 mesh sieve, is obtained product original Feed powder.
It further, will be described in a kind of red capsule formula living of the present invention and preparation method thereof embodiment Products material powder fills capsule with automatic tire bagger, and capsule inner stuffing specification is 300mg/, and filled capsule is carried out Polishing, obtains finished capsule product.
It further, will be described in a kind of red capsule formula living of the present invention and preparation method thereof embodiment Finished capsule product is transferred in plastic bottle or aluminum-plastic packaged to get to packaged red living capsule product.
It further, will be described in a kind of red capsule formula living of the present invention and preparation method thereof embodiment Packaged red capsule product living carries out 60Coradiation sterilizing, and average overall absorption amount is 4KGY, and unevenness≤2 are finally pressed It is fitted into box up to final red capsule finished product living according to regulation.
The technical problem to be solved in the present invention is to provide a kind of red capsule formula living and preparation method thereof, it is therefore intended that slow The fatigue that the solution mankind bring by work or other labour.

Claims (8)

1. a kind of red living capsule formula and preparation method thereof, the formula by:American Ginseng (1), the fruit of Chinese wolfberry (2), prepared rehmannia root (3), puncture vine (4), Herba Epimedii (5), sealwort (6) composition, which is characterized in that described American Ginseng (1) 150g, the fruit of Chinese wolfberry (2) 100g, prepared rehmannia root (3) 100g, puncture vine (4) 120g, Herba Epimedii (5) 50g, sealwort (6) 50g are fabricated to by its preparation process 1000, every weight 0.3g.
2. a kind of red capsule formula living according to claim 1 and preparation method thereof, which is characterized in that by described the West Join (1) clean slice, into pulverizer in fully crushed, sieve with 100 mesh sieve, obtain spare ginseng powder.
3. a kind of red capsule formula living according to claim 1 and preparation method thereof, which is characterized in that claim by formula rate The fruit of Chinese wolfberry (2) is taken, prepared rehmannia root (3), puncture vine (4), Herba Epimedii (5), sealwort (6) is washed and chopped, by the mixture of chopping It is placed in extractor, adds in the water of 10 times of amounts of medicinal material total weight, under conditions of 100 DEG C of constant temperature, extract 2 hours, extract 2 hours The remaining dregs of a decoction repeat to extract once, are then combined with leaching liquor twice, and leaching liquor is stood 24 hours according still further to aforesaid operations afterwards Afterwards, clear liquid is obtained by filtration.
4. a kind of red capsule formula living according to claim 1 or 3 and preparation method thereof, which is characterized in that will be above-mentioned clear Liquid filtering is concentrated under reduced pressure into the concentrate (80 DEG C of temperature, vacuum degree 0.06-0.09MPa) that relative density is 1.20~1.25.
5. a kind of red capsule formula living according to claim 2 or 4 and preparation method thereof, which is characterized in that will be described Spare ginseng powder, which is added in above-mentioned concentrate, to be sufficiently mixed uniformly, through 60 DEG C of dryings, crushing, is crossed 80 mesh sieve, is obtained product original Feed powder.
6. a kind of red capsule formula living and preparation method thereof according to claim 1 or 5, which is characterized in that will be described Products material powder fills capsule with automatic tire bagger, and capsule inner stuffing specification is 300mg/, and filled capsule is carried out Polishing, obtains finished capsule product.
7. a kind of red capsule formula living according to claim 1 or 6 and preparation method thereof, which is characterized in that will be described Finished capsule product is transferred in plastic bottle or aluminum-plastic packaged to get to packaged red living capsule product.
8. a kind of red capsule formula living according to claim 1 or 7 and preparation method thereof, which is characterized in that will be described Packaged red capsule product living carries out 60Coradiation sterilizing, and average overall absorption amount is 4KGY, and unevenness≤2 are finally pressed It is fitted into box up to final red capsule finished product living according to regulation.
CN201810267289.1A 2018-03-28 2018-03-28 A kind of red capsule formula living and preparation method thereof Pending CN108186891A (en)

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Application Number Priority Date Filing Date Title
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CN108186891A true CN108186891A (en) 2018-06-22

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050276872A1 (en) * 2001-08-31 2005-12-15 Chan Pui-Kwong Composition comprising Xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof
CN101773606A (en) * 2010-03-15 2010-07-14 武汉代代木生物科技有限公司 Preparation capable of nursing essence, replenishing qi, refreshing spirit and balancing yin and yang and preparation method thereof
CN103211219A (en) * 2013-04-25 2013-07-24 福建永生活力生物工程有限公司 Health food for relieving physical fatigue and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050276872A1 (en) * 2001-08-31 2005-12-15 Chan Pui-Kwong Composition comprising Xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof
CN101773606A (en) * 2010-03-15 2010-07-14 武汉代代木生物科技有限公司 Preparation capable of nursing essence, replenishing qi, refreshing spirit and balancing yin and yang and preparation method thereof
CN103211219A (en) * 2013-04-25 2013-07-24 福建永生活力生物工程有限公司 Health food for relieving physical fatigue and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
平水胡: "辅酶QIO", 《百度文库》 *

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Application publication date: 20180622

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