CN108159304A - A kind of decoction medicine and preparation method that can effectively treat climacteric syndrome - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of decoction medicine that can effectively treat climacteric syndrome according to the understanding mechanism of Chinese traditional treatment climacteric syndrome, each component and its mass parts ratio of the drug are as follows：3~12g of radix bupleuri, 15~35g of Fructus Tritici Levis, 3~12g of Radix Glycyrrhizae, 10~16g of jujube, 3~12g of radix scutellariae, 6~16g of Radix Paeoniae Alba, 8~16g of Radix Angelicae Sinensis, 15~35g of prepared rehmannia root, 10~16g of Poria cocos, 6~12g of rhizoma alismatis, 5~16g of Rhizoma Atractylodis Macrocephalae, 5~12g of Rhizoma Chuanxiong, 15~55g of calcined CONCHA HALIOTIDIS, 6~15g of lily, 10~16g of radix scrophulariae, 10~16g of calcined Dragon's bone, 20~35g of calcined oyster shell, 8~16g of Radix Salviae Miltiorrhizae, 10~16g of mulberry fruit, 10~25g of Polygonum multiflower knotweed；Drug provided by the invention is a good Chinese prescription.

Description

A kind of decoction medicine and preparation method that can effectively treat climacteric syndrome

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of decoction medicine that can effectively treat climacteric syndrome, The decoction medicine particularly used for climacteric syndrome patient and the field of preparation method.

Background technology

Motherland's medicine thinks：Perimenopausal syndrome is also known as menopausal syndrome（MPS）, refer to appearance property before and after postmenopausal women It is a series of based on function disorder of autonomic nervous system caused by hormonal fluctuations or reduction, with one group of disease of neuropsychological symptom Hou Qun.Menopause can be divided into two kinds of natural menopause and artificial menopause.Natural menopause refers to ovarian follicle in ovary and uses up or remaining ovarian follicle pair Promoting sexual gland hormone loses reaction, and estrogen is no longer developed and secreted to ovarian follicle, it is impossible to stimulate endometrial growth, lead to menopause. Artificial menopause refers to operation excision bilateral ovaries or stops ovarian function, such as radiotherapy and chemotherapy with other methods.Individually It cuts off uterus and retains side or bilateral ovaries person, not as artificial menopause.

Most typical symptom is hectic fever, flush in perimenopausal syndrome.45~55 years old is mostly occurred in, most of women can There is the symptom that weight does not wait, someone has started to occur in menopause transition symptom, continues to post menopausal 2~3 years, a few peoples can Continue to that 5~10 years symptoms of post menopausal are just mitigated or disappeared.Artificial menopause person often may occur in which for 2 weeks after surgery to be enclosed absolutely Menstrual period syndrome, postoperative 2 months reach peak, sustainable 2 years as long as.

1. change in menstrual cycle characteristics

Change in menstrual cycle is that climacteric earliest clinical symptoms occurs, is divided into 3 types：

（1）Menstrual cycle extends, and is reduced through amount, last menopause.

（2）Menstrual cycle is irregular, and menostaxis, menorrhagia or even massive haemorrhage or bleeding dripping urine endlessly, then gradually It reduces and stops.

（3）Menstruation stops suddenly, more rare.Due to ovary No-clay weak interbed, endometrium easily occurs for estrogen level fluctuation Cancer.For abnormal bleeding person, should row diagnostic curettage, exclude canceration.

2. vasomotor symptoms

Clinical manifestation is：Hectic fever, perspiration are the unstable performances of vasomotoricity, are that perimenopausal syndrome is most prominent Characteristic symptom.Hectic fever is risen from shirtfront, is poured into incidence, is then involved whole body, a small number of women are limited to head, neck and breast. Feel scorching hot in the region patient of flush, rubefaction is and then explosive to perspire.Last for several seconds is differed to several minutes, is broken out Frequency is daily for several times to 30~50 times.Night or stress situation easily inspire.Such vascular function is unstable to last 1 year, sometimes It is as long as five years or longer.

So, it is people in the art with regard to how to find a kind of Chinese medicine composition that can effectively treat climacteric syndrome The problem of member is urgently to be resolved.

Invention content

With the continuous development of China's traditional Chinese medicine, in treatment climacteric syndrome, during people gradually appreciate The advantages for the treatment of climacteric syndrome is cured, and good effect, the advantages such as quick, toxic side effect is small over the course for the treatment of, for existing There is the present situation of western medical treatment climacteric syndrome, the purpose of the invention is to provide one kind can effectively treat climacteric syndrome Decoction medicine, to solve the problems, such as that climacteric syndrome patient gets well early.The drug is using common Chinese medicine as original Material, by selecting rational drug and mass parts ratio, can effectively treat above-mentioned climacteric syndrome.

To achieve the purpose that foregoing invention, the technical solution adopted in the present invention is：Climacteric can effectively be treated by providing one kind The decoction medicine and preparation method of phase syndrome, which is characterized in that each component and mass parts of the drug are than as follows：

3~12g of radix bupleuri, 15~35g of Fructus Tritici Levis, 3~12g of Radix Glycyrrhizae, 10~16g of jujube, 3~12g of radix scutellariae, 6~16g of Radix Paeoniae Alba, when Return 8~16g, 15~35g of prepared rehmannia root, 10~16g of Poria cocos, 6~12g of rhizoma alismatis, 5~16g of Rhizoma Atractylodis Macrocephalae, 5~12g of Rhizoma Chuanxiong, calcined CONCHA HALIOTIDIS 15~55g, 6~15g of lily, 10~16g of radix scrophulariae, 10~16g of calcined Dragon's bone, 20~35g of calcined oyster shell, 8~16g of Radix Salviae Miltiorrhizae, mulberry fruit 10 ~16g, 10~25g of Polygonum multiflower knotweed.

A kind of decoction medicine and preparation method that can effectively treat climacteric syndrome, which is characterized in that the drug Each component and mass parts are than as follows：

4~11g of radix bupleuri, 16~31g of Fructus Tritici Levis, 4~11g of Radix Glycyrrhizae, 11~14g of jujube, 4~11g of radix scutellariae, 7~14g of Radix Paeoniae Alba, when Return 9~14g, 16~31g of prepared rehmannia root, 11~14g of Poria cocos, 7~11g of rhizoma alismatis, 6~14g of Rhizoma Atractylodis Macrocephalae, 6~11g of Rhizoma Chuanxiong, calcined CONCHA HALIOTIDIS 16~48g, 7~14g of lily, 11~14g of radix scrophulariae, 11~14g of calcined Dragon's bone, 23~31g of calcined oyster shell, 9~14g of Radix Salviae Miltiorrhizae, mulberry fruit 11 ~15g, 11~22g of Polygonum multiflower knotweed.

A kind of decoction medicine and preparation method that can effectively treat climacteric syndrome, which is characterized in that the drug Each component and mass parts are than as follows：

Radix bupleuri 10g, Fructus Tritici Levis 28g, Radix Glycyrrhizae 10g, jujube 13g, radix scutellariae 10g, Radix Paeoniae Alba 13g, Radix Angelicae Sinensis 13g, 16~31g of prepared rehmannia root, 11~14g of Poria cocos, 7~11g of rhizoma alismatis, 6~14g of Rhizoma Atractylodis Macrocephalae, 6~11g of Rhizoma Chuanxiong, calcined CONCHA HALIOTIDIS 42g, lily 13g, radix scrophulariae 13g, dragon is forged Bone 13g, calcined oyster shell 28g, Radix Salviae Miltiorrhizae 13g, mulberry fruit 13g, Polygonum multiflower knotweed 20g.

A kind of decoction medicine and preparation method that can effectively treat climacteric syndrome, which is characterized in that the method packet Following steps are included to be prepared：

A, it after above-mentioned raw materials Chinese medicine being picked impurity and dust, is respectively crushed into coarse according to mass parts ratio and decocts a drug wrapped；

B, 1. the raw material Chinese medicine wrapped is put into cold boiling water and impregnates 45min, then again by soaked drug and soak medicine Clarified solution be put into marmite together, the cold boiling water for injecting medicine 66mm carries out first time high heat decoction, waits to decoct to 15min When, turn slow boiling and boil 35 min, leaching liquid；2. the slightly warm water that medicine 62mm was re-injected in the dregs of a decoction carries out second of intense fire It decocts, when decocting to 10min, turns slow boiling and boil 30 min, leaching liquid；It is condensed into 50% 3. liquid twice is mixed Liquid 540ml（Milliliter）.

A kind of decoction medicine and preparation method that can effectively treat climacteric syndrome, which is characterized in that the side of taking Method is：The Chinese medicine liquid prepared was taken with one day, once a dose in the morning, afternoon and evening, dosage 180ml（Milliliter）/ time, it takes advantage of and warmly takes, together Shi Peihe mental and psychological treatments.30 days as a treatment course, 2~6 courses for the treatment of of taking medicine, symptom disappear, and disease accuses recovery from illness.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine It carries.It is raw material that the present invention, which selects one of the most common Chinese medicine, gives full play to the pharmacological effect of each component：

Radix bupleuri, nature and flavor：There is inducing diaphoresis to bring down a fever, soothing liver-qi stagnation, rise the effect of lifting yang-energy for bitter, pungent, cold nature, outer for treating Feel fever, fevers and chills alternate, malaria, liver-depressed hypochondrium pain mammary swelling, have a headache dizzy, irregular menstruation, the rectal prolapse of collapse from qi deficiency, the prolapse of uterus, The diseases such as gastroptosis；

Fructus Tritici Levis, nature and flavor：It is sweet in flavor, cool in nature, there is the effect of except abnormal heat, hidroschesis, for treating hectic fever due to yin labor heat, spontaneous sweating；

Radix Glycyrrhizae, nature and flavor：It is sweet, flat, have invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription the effect of, use It swells in treatment burnout deficiency of food, the thin face Huang of flesh, palpitation, abdominal pain loose stool, four limbs contraction, hysteria, cough and asthma, throat Bitterly, ulcerative carbuncle swelling and pain, infant fetal toxin and drug, food poisoning；

Jujube, nature and flavor：It is sweet, warm, there is tonifying spleen and stomach, replenishing qi and blood, tranquilizing mind, adjust the effect of Ying Wei and pharmacological property, for treating taste The diseases such as weakness, insufficiency of vital energy and blood, anorexia and loose stool, lassitude hypodynamia, palpitation and insomnia, hysteria of womam, disharmony between ying and wei；

Radix rehmanniae recen, nature and flavor：It is sweet in flavor, bitter, cold in nature, there is the effect of heat-clearing, cool blood, enter ying blood, high fever for treating warm heat disease heat Coma, dry tongue are deep red；

Radix scutellariae, nature and flavor：It is bitter, cold in nature, there is the effect of heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis, tocolysis, for treating damp-warm syndrome, heat Wet, chest tightness and emesis, damp and hot feeling of fullness, rush down dysentery, jaundice, cough with lung heat, hyperpyrexia polydipsia, blood-head tells nosebleed, carbuncle sore tumefacting virus, fetal irritability；

Radix Paeoniae Alba, nature and flavor：Hardship, is slightly cold at acid, has the effect of smooth liver and relieve pain, nourishing blood for regulating menstruation, astringing YIN to stop sweating, dizzy for treating headache The diseases such as dizzy, hypochondriac pain, abdominal pain, four limbs contraction pain, blood deficiency chlorosis, irregular menstruation, spontaneous perspiration, night sweat；

Radix Angelicae Sinensis, nature and flavor：Warm-natured, acrid-sweet flavor, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation the effect of, for treat the deficiency of blood, Sallow complexion, dizziness palpitaition, the deficiency of blood have the stagnant irregular menstruation of the stasis of blood, Amenorrhea, dysmenorrhoea, deficient cold type abdominal pain, coronary heart disease heart strand concurrently Bitterly, arthralgia pain due to rheumatism, traumatic injury；

Prepared rehmannia root, nature and flavor：Sweet, tepor has the effect of nourishing yin and supplementing blood, beneficial to spirit and marrow, for treating the deficiency of liver-yin and kidney-yin, waist and knee acid Soft, osteopyrexia and fever, night sweat seminal emission, Heat Diabetes, blood deficiency chlorosis, palpitation and severe palpitation, irregular menstruation, metrostaxis, dizziness, tinnitus, Poliosis；

Poria cocos, nature and flavor：It is sweet in flavor, light, mild-natured, there is the effect of clearing damp and promoting diuresis, invigorating the spleen, calming heart, for treating oedema oliguria, phlegm and retained fluid Feel dizzy and heart palpitations, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear；

Rhizoma alismatis, nature and flavor：It is sweet in flavor, light, cold in nature, have clearing damp and promoting diuresis, expel the heat-evil, change the effect of turbid lipid-loweringing, for treat difficult urination, Oedema turgor, oliguria of having loose bowels, phlegmatic vertigo, puckery pain of heat gonorrhea, hyperlipidemia；

Rhizoma Atractylodis Macrocephalae, nature and flavor：It is bitter, sweet, warm, there is the effect of air making-up and spleen enlivening, eliminate dampness and have diuretic effect, hidroschesis, tocolysis, for treating Spleen-Qi Deficiency Weak, anorexia and loose stool, phlegm and retained fluid oedema, exterior deficiency spontaneous perspiration, fetal irritability；

Rhizoma Chuanxiong, nature and flavor：It is pungent, warm, there is the effect of wet promote breath and open depression, method wind-dryness, promoting blood circulation and stopping pain, for treating air-cooled headache rotation Dizzy, hypochondriac pain abdomen pain, arthritis muscle contraction, Amenorrhea, difficult labour, postpartum stasis block pain, ulcer sores, irregular menstruation, lump in the abdomen abdominal pain, chest side of body thorn Bitterly, tumbling and swelling, arthralgia pain due to rheumatism；

Calcined CONCHA HALIOTIDIS, nature and flavor：It is micro- it is salty, be slightly cold, there is the effect of tonifying liver cloudy, removing heat from the liver, for treating yin deficiency yang hyperactivity or liver-yang The solely diseases such as high caused twitch, dizziness, glaucoma night blindness, cataract；

Lily, nature and flavor：It is sweet in flavor, cold in nature, there is the effect of Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing, for treating deficiency of Yin cough caused by dryness, overstrain cough cough It is blood, dysphoria palpitates with fear, insomnia and dreamful sleep, absent-minded；

Radix scrophulariae, nature and flavor：It is sweet, bitter, salty, be slightly cold, have clearing heat and cooling blood, nourishing yin and lessening fire, detoxicating and resolving a mass the effect of, for treat warm Sick heat and ying blood, body heat, polydipsia, tongue is deep red, hair spot, hectic fever due to yin labor is coughed, puckery dim-sighted, the throat larynx of awake, Tianjin hinder constipation, mesh does not swell dysphoria Bitterly, scrofula subcutaneous nodule, skin sore；

Calcined Dragon's bone, nature and flavor：It is puckery, sweet, mild-natured, there is the effect of tranquillizing the mind by relieving convulsion, arrest sweating controlling nocturnal emission with astringent drugs, the puckery intestines of hemostasis, myogenic sore, use In treatment frightened epilepsy is demented, palpitation is forgetful, insomnia and dreamful sleep, spontaneous sweating, seminal emission stranguria with turbid discharge, hematemesis are had blood in stool, under uterine bleeding band, rush down dysentery takes off Anus, ulcer do not close up long；

Calcined oyster shell, nature and flavor：It is salty wet, cool, there is the effect of holding back the moon, checking exuberance of yang, hidroschesis, puckery essence, resolving sputum, softening hard masses, for treat frightened epilepsy, Dizziness, spontaneous perspiration, night sweat, seminal emission, stranguria with turbid discharge, uterine bleeding, band under, scrofula, goiter and tumor；Calcined oyster shell restrains astringent method, for spontaneous sweating, seminal emission Collapse band, stomachache acid regurgitation；

Radix Salviae Miltiorrhizae, nature and flavor：Bitter, cold nature have the effect of promoting blood circulation, menstruction regulating and pain relieving, nourishing blood and tranquilization, cool blood to disappear carbuncle, are used for Treat menoxenia, dysmenorrhoea, Amenorrhea, postpartum stasis of blood, trusted subordinate's pain, a lump in the abdomen causing distension and pain, the swelling and pain of hot numbness, traumatic injury, Heat enters ying blood, dysphoria, vexed insomnia, ulcerative carbuncle pyogenic infections；

Pigs Hearts, nature and flavor：It is sweet in flavor, salty, mild-natured, there is the effect of mental-tranquilization, relieving convulsion, for treating palpitation with fear palpitation, spontaneous perspiration, mistake It sleeps, wandering, the illnesss such as insane, mad, epilepsy；

Mulberry fruit, nature and flavor：Nature and flavor are sweet, sour, cold, have the effect of enriching blood enriching yin, fluid dryness, for treating dizziness and tinnitus, palpitaition Insomnia, poliosis, injury thirst, Heat Diabetes, blood deficiency and constipation；

Polygonum multiflower knotweed, nature and flavor：It is sweet in flavor, slight bitter, mild-natured, there is the effect of mental-tranquilization, wind-dispelling, dredging collateral, for treating insomnia, more Dream, deficiency of blood bodily pain, numbness, arthralgia pain due to rheumatism, rubella itch.

Drug of the present invention is the principle based on Chinese traditional treatment climacteric syndrome, from the pathology machine according to climacteric syndrome System and pharmacological action are thought：With regard to climacteric syndrome, each raw material herbal medicine efficacy in drug provided by the present invention is played altogether, to upper Stating disease has good therapeutic effect.

Specific embodiment

A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned climacteric syndrome, using the formula system Standby medicine effect is good, quick, is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the present invention's Specific embodiment is described in further detail：

Embodiment 1：

A kind of decoction medicine that can effectively treat climacteric syndrome, which is characterized in that each component and quality of the drug Part is than as follows：

Radix bupleuri 10g, Fructus Tritici Levis 28g, Radix Glycyrrhizae 10g, jujube 13g, radix scutellariae 10g, Radix Paeoniae Alba 13g, Radix Angelicae Sinensis 13g, 16~31g of prepared rehmannia root, 11~14g of Poria cocos, 7~11g of rhizoma alismatis, 6~14g of Rhizoma Atractylodis Macrocephalae, 6~11g of Rhizoma Chuanxiong, calcined CONCHA HALIOTIDIS 42g, lily 13g, radix scrophulariae 13g, dragon is forged Bone 13g, calcined oyster shell 28g, Radix Salviae Miltiorrhizae 13g, mulberry fruit 13g, Polygonum multiflower knotweed 20g.

Embodiment 2：

A kind of decoction medicine that can effectively treat climacteric syndrome, which is characterized in that each component and quality of the drug Part is than as follows：

Radix bupleuri 11g, Fructus Tritici Levis 31g, Radix Glycyrrhizae 11g, jujube 14g, radix scutellariae 11g, Radix Paeoniae Alba 14g, Radix Angelicae Sinensis 14g, prepared rehmannia root 31g, Poria cocos 14g, rhizoma alismatis 11g, Rhizoma Atractylodis Macrocephalae 14g, Rhizoma Chuanxiong 11g, calcined CONCHA HALIOTIDIS 48g, lily 14g, radix scrophulariae 14g, calcined Dragon's bone 14g, calcined oyster shell 31g, Radix Salviae Miltiorrhizae 14g, mulberry fruit 15g, Polygonum multiflower knotweed 22g.

Embodiment 3：

A kind of decoction medicine that can effectively treat climacteric syndrome, which is characterized in that each component and quality of the drug Part is than as follows：

Radix bupleuri 12g, Fructus Tritici Levis 35g, Radix Glycyrrhizae 12g, jujube 16g, radix scutellariae 12g, Radix Paeoniae Alba 16g, Radix Angelicae Sinensis 16g, prepared rehmannia root 35g, Poria cocos 16g, rhizoma alismatis 12g, Rhizoma Atractylodis Macrocephalae 16g, Rhizoma Chuanxiong 12g, calcined CONCHA HALIOTIDIS 55g, lily 15g, radix scrophulariae 16g, calcined Dragon's bone 16g, calcined oyster shell 35g, Radix Salviae Miltiorrhizae 16g, mulberry fruit 16g, Polygonum multiflower knotweed 25g.

Model case：

Through clinical conditions climacteric syndrome patient totally 1390, the age is 725 of 57 years old or more, and only 665 are Less than 57 years old.That fully recovers in 1390 patients has 1060, effective 261, invalid 69.Total effective rate is up to 95%.

Claims (3)

1. a kind of decoction medicine that can effectively treat climacteric syndrome, which is characterized in that each component and matter of the drug Part is measured than as follows：

3~12g of radix bupleuri, 15~35g of Fructus Tritici Levis, 3~12g of Radix Glycyrrhizae, 10~16g of jujube, 3~12g of radix scutellariae, 6~16g of Radix Paeoniae Alba, when Return 8~16g, 15~35g of prepared rehmannia root, 10~16g of Poria cocos, 6~12g of rhizoma alismatis, 5~16g of Rhizoma Atractylodis Macrocephalae, 5~12g of Rhizoma Chuanxiong, calcined CONCHA HALIOTIDIS 15~55g, 6~15g of lily, 10~16g of radix scrophulariae, 10~16g of calcined Dragon's bone, 20~35g of calcined oyster shell, 8~16g of Radix Salviae Miltiorrhizae, mulberry fruit 10 ~16g, 10~25g of Polygonum multiflower knotweed.

2. the decoction medicine according to claim 1 that can effectively treat climacteric syndrome, which is characterized in that the drug Each component and mass parts than as follows：

4~11g of radix bupleuri, 16~31g of Fructus Tritici Levis, 4~11g of Radix Glycyrrhizae, 11~14g of jujube, 4~11g of radix scutellariae, 7~14g of Radix Paeoniae Alba, when Return 9~14g, 16~31g of prepared rehmannia root, 11~14g of Poria cocos, 7~11g of rhizoma alismatis, 6~14g of Rhizoma Atractylodis Macrocephalae, 6~11g of Rhizoma Chuanxiong, calcined CONCHA HALIOTIDIS 16~48g, 7~14g of lily, 11~14g of radix scrophulariae, 11~14g of calcined Dragon's bone, 23~31g of calcined oyster shell, 9~14g of Radix Salviae Miltiorrhizae, mulberry fruit 11 ~15g, 11~22g of Polygonum multiflower knotweed.

3. the decoction medicine that can effectively treat climacteric syndrome according to claim 1 to 2, which is characterized in that described The each component and mass parts of drug are than as follows：

Radix bupleuri 10g, Fructus Tritici Levis 28g, Radix Glycyrrhizae 10g, jujube 13g, radix scutellariae 10g, Radix Paeoniae Alba 13g, Radix Angelicae Sinensis 13g, 16~31g of prepared rehmannia root, 11~14g of Poria cocos, 7~11g of rhizoma alismatis, 6~14g of Rhizoma Atractylodis Macrocephalae, 6~11g of Rhizoma Chuanxiong, calcined CONCHA HALIOTIDIS 42g, lily 13g, radix scrophulariae 13g, dragon is forged Bone 13g, calcined oyster shell 28g, Radix Salviae Miltiorrhizae 13g, mulberry fruit 13g, Polygonum multiflower knotweed 20g.