CN108143882A - 一种治疗肾虚引起的腰膝酸软的中药组合物及制备方法 - Google Patents

一种治疗肾虚引起的腰膝酸软的中药组合物及制备方法 Download PDF

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CN108143882A
CN108143882A CN201810035938.5A CN201810035938A CN108143882A CN 108143882 A CN108143882 A CN 108143882A CN 201810035938 A CN201810035938 A CN 201810035938A CN 108143882 A CN108143882 A CN 108143882A
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waist
chinese medicine
soreness
weakness
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夏瑜
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Chengdu Fuhaosi Biotechnology Co Ltd
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Abstract

本发明属于中药制剂领域，目的是根据中医治疗肾虚引起的腰膝酸软的认识机理而提供一种治疗肾虚引起的腰膝酸软的中药组合物，所述中药组合物的各个组分及其质量份比如下：淫羊藿30～120g、熟地黄120～350g、菟丝子（盐炒）100～160g、山萸肉60～150g、枸杞子50～160g、泽泻60～100g、冬虫夏草30～100g、茯苓100～160g、肉苁蓉100～160g、红景天30～70g、山药150～350g、黄茋100～350g、北沙参50～100g、西红花10～45g、牡丹皮60～150g；本发明提供的药物是一个很好的中药组方。

Description

一种治疗肾虚引起的腰膝酸软的中药组合物及制备方法
技术领域
本发明属于中药制剂领域，具体涉及一种治疗肾虚引起的腰膝酸软的中药组合物，特别是供肾虚引起的腰膝酸软患者使用的中药组合物及制备方法的领域。
背景技术
据有关文献显示：腰膝酸软（soreness and weakness of waist and knees）为中医肝肾亏损的一种症状。表现为腰部和膝部的酸软无力，同时可伴腰痛发凉、手脚凉、四肢无力，头晕目眩、视物昏花等其他肾虚症状。治疗宜排除泌尿系统、骨骼及其他器质性疾病，采用中医辨证调理方法，给予通畅气血、补益肝肾，滋阴壮阳。
那么，就如何找到一种可有效治疗肾虚引起的腰膝酸软的中药组合物，是本领域技术人员亟待要解决的问题。
发明内容
随着我国中医中药学的不断发展，在治疗肾虚引起的腰膝酸软上，人们逐渐意识到了中医治疗肾虚引起的腰膝酸软的优点，且在治疗过程中疗效好、见效快、毒副作用小等优势，针对现有西医治疗肾虚引起的腰膝酸软的现状，本发明的目的是在于提供一种治疗肾虚引起的腰膝酸软的中药组合物，以解决肾虚引起的腰膝酸软患者早日恢复健康的问题。该药物是以常见的中药为原料，通过选择合理的药物及质量份比，可有效治疗上述肾虚引起的腰膝酸软。
为达到上述发明的目的，本发明所采用的技术方案为：提供一种治疗肾虚引起的腰膝酸软的中药组合物及制备方法，其特征在于，所述中药组合物的各个组分及质量份比如下所示：
淫羊藿30～120g、熟地黄120～350g、菟丝子（盐炒）100～160g、山萸肉60～150g、枸杞子50～160g、泽泻60～100g、冬虫夏草30～100g、茯苓100～160g、肉苁蓉100～160g、红景天30～70g、山药150～350g、黄茋100～350g、北沙参50～100g、西红花10～45g、牡丹皮60～150g，辅料：微粉硅胶、微晶纤维素和淀粉适量。
一种治疗肾虚引起的腰膝酸软的中药组合物及制备方法，其特征在于，所述中药组合物的各个组分及质量份比如下所示：
淫羊藿36～105g、熟地黄135～310g、菟丝子（盐炒）115～140g、山萸肉70～130g、枸杞子56～140g、泽泻70～90g、冬虫夏草36～90g、茯苓115～140g、肉苁蓉115～140g、红景天36～60g、山药180～310g、黄茋115～310g、北沙参56～90g、西红花12～40g、牡丹皮70～130g，辅料：微粉硅胶、微晶纤维素和淀粉适量。
一种治疗肾虚引起的腰膝酸软的中药组合物及制备方法，其特征在于，所述中药组合物的各个组分及质量份比如下所示：
淫羊藿95g、熟地黄280g、菟丝子（盐炒）120g、山萸肉115g、枸杞子120g、泽泻80g、冬虫夏草80g、茯苓120g、肉苁蓉120g、红景天52g、山药280g、黄茋280g、北沙参80g、西红花35g、牡丹皮115g，辅料：微粉硅胶、微晶纤维素和淀粉适量。
一种治疗肾虚引起的腰膝酸软的中药组合物及制备方法，其特征在于，所述方法包括如下步骤制备而成：
A、将上述原料中药拣去杂质和粉尘后，按照质量份比共粉碎成（30～50目）颗粒状包煎；
B、①将包好的原料中药放入冷开水中浸泡50min，然后再将浸泡好的药物放入砂锅内，加入原料中药重量7～9倍的冷开水进行第一次武火煎煮，待煎煮到18min时，转文火熬制120min，滤取药液；②药渣中再次加入原料中药重量6～8 倍的冷开水进行第二次武火煎煮，待煎煮到15min时，转文火熬制110min，滤取药液；③将二次药液混合浓缩成相对密度为1.08 的清膏，然后干燥、研末和消毒后备用；
C、①按照传统制备中药胶囊剂的方法，将B中研磨好的细末过筛后，加入适量的微粉硅胶、微晶纤维素和淀粉混合均匀，然后制备成胶囊剂（其胶囊锁合后总长度为23.3mm，药粉容量0.4～0.5g/粒），②继而抛光，消毒，分装密封即可。
一种治疗肾虚引起的腰膝酸软的中药组合物及制备方法，其特征在于，所述服用方法为：将制备好的胶囊剂药物以每日三次服用，早中晚各服一次，给药量2.5g（5粒）/次，饭前服。30天为一个疗程，服药1～3个疗程，症状逐渐好转，并痊愈。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料，充分发挥各组分的药理功效：
淫羊藿，性味：味辛、甘、性温，具有补肾壮阳、祛风除湿、强筋键骨之功效，用于治疗阳痿遗精、虚冷不育、尿频失楚、肾虚喘咳、腰膝酸软、风湿痹痛、半身不遂、四肢不仁等症；
熟地黄，性味：甘、微温，具有滋阴补血、益精填髓之功效，用于治疗肝肾阴虚、腰膝酸软、骨蒸潮热、盗汗遗精、内热消渴、血虚萎黄、心悸怔忡、月经不调、崩漏下血、眩晕、耳鸣、须发早白；
菟丝子（盐炒），性味：温、甘，具有滋补肝肾、安胎、明目、止泻的功效，用于阳痿遗精、尿有余沥、遗尿尿频、腰膝酸软、目昏耳鸣、肾虚胎漏、胎动不安、脾肾虚泻，外治白癜风；
山萸肉，性味：酸、涩、微温，具有补益肝肾、涩精固脱之功效，用于治疗眩晕耳鸣、腰膝酸痛、阳痿遗精、遗尿尿频、崩漏带下、大汗虚脱、内热消渴；
枸杞子，性味：味甘、性平，具有养肝、滋肾、润肺之功效，用于治疗肝肾亏虚、头晕目眩、目视一清、腰膝酸软、阳痿贵精、虚劳咳嗽、消渴引饮；
泽泻，性味：甘、寒，具有利小便、清湿热之功效，用于治疗小便不利、水肿胀满、泄泻尿少、痰饮眩晕、热淋涩痛，高血脂等症；
冬虫夏草，性味：甘、平，具有补肺益肾、止血、化痰之功效，属补虚药下属分类的补阳药，用于治疗久咳虚喘、劳嗽咯血、阳痿遗精、腰膝酸痛；
茯苓，性味：味甘、淡、性平，具有利水渗湿、健脾、宁心之功效，用于治疗水肿尿少、痰饮眩悸、脾虚食少、便溏泄泻、心神不安、惊悸失眠；
肉苁蓉，性味：味甘、咸、性温，具有补肾阳、益精血、润肠道之功效，用于治疗肾阳虚衰、精血不足之阳痿、遗精、白浊、尿频余沥、腰痛脚弱、耳鸣目花、月经衍期、宫寒不孕、肠燥便秘；
红景天，性味：味甘、苦、性平，具有益气活血、通脉平喘之功效，用于治疗气虚血瘀、胸痹心痛、中风偏瘫、倦怠气喘；
山药，味辛、性平、味甘，具有补脾养胃、生津益肺、补肾涩精之功效，属补虚药下属分类的补气药，用于治疗脾虚食少、久泻不止、肺虚喘咳、肾虚遗精、带下、尿频、虚热消渴等，麸炒山药补脾健胃，用治脾虚食少、泄泻便溏、白带过多；
黄茋，性味：甘、微温，具有补气固表、利尿托毒、排脓、敛疮生肌之功效，用于治疗气虚乏力、食少便溏、中气下陷、久泻脱肛、便血崩漏、表虚自汗、气虚水肿、痈疽难溃、久溃不敛、血虚痿黄、内热消渴、慢性肾炎蛋白尿、糖尿病等症；
北沙参，性味：味甘、微苦、性微寒，具有养阴清肺、益胃生津之功效，属补虚药下属分类的补阴药，用于治疗肺热燥咳、劳嗽痰血、热病津伤口渴；
西红花，性味：味甘、性平，具有活血化瘀、凉血解毒、解郁安神之功效，用于治疗经闭症瘕、产后瘀阻、温毒发斑、忧郁痞闷、惊悸发狂；
牡丹皮，性味：苦、辛、微寒，具有清热凉血、活血化瘀之功效，用于治疗热入营血、温毒发斑、吐血衄血、夜热早凉、无汗骨蒸、经闭痛经、跌扑伤痛、痈肿疮毒。
本发明药物是基于中医治疗肾虚引起的腰膝酸软的原则，从依据肾虚引起的腰膝酸软的病理机制及药理作用认为：就肾虚引起的腰膝酸软，本发明所提供的药物中的各原料中药药效共奏，对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述肾虚引起的腰膝酸软的治疗而提出的一种中药配方，采用该配方制备的药物药效好，见效快，是一个很好的中药组方，特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述：
实施例1：
一种治疗肾虚引起的腰膝酸软的中药组合物，其特征在于，所述中药组合物的各个组分及质量份比如下所示：
淫羊藿95g、熟地黄280g、菟丝子（盐炒）120g、山萸肉115g、枸杞子120g、泽泻80g、冬虫夏草80g、茯苓120g、肉苁蓉120g、红景天52g、山药280g、黄茋280g、北沙参80g、西红花35g、牡丹皮115g，辅料：微粉硅胶、微晶纤维素和淀粉适量。
实施例2：
一种治疗肾虚引起的腰膝酸软的中药组合物，其特征在于，所述中药组合物的各个组分及质量份比如下所示：
淫羊藿105g、熟地黄310g、菟丝子（盐炒）140g、山萸肉130g、枸杞子140g、泽泻90g、冬虫夏草90g、茯苓140g、肉苁蓉140g、红景天60g、山药310g、黄茋310g、北沙参90g、西红花40g、牡丹皮130g，辅料：微粉硅胶、微晶纤维素和淀粉适量。
实施例3：
一种治疗肾虚引起的腰膝酸软的中药组合物，其特征在于，所述中药组合物的各个组分及质量份比如下所示：
淫羊藿120g、熟地黄350g、菟丝子（盐炒）160g、山萸肉150g、枸杞子160g、泽泻100g、冬虫夏草100g、茯苓160g、肉苁蓉160g、红景天70g、山药350g、黄茋350g、北沙参100g、西红花45g、牡丹皮60～150g，辅料：微粉硅胶、微晶纤维素和淀粉适量。
典型病例：
经临床诊断治疗肾虚引起的腰膝酸软患者共1310例，年龄为49岁以上的675例，只有635例为49岁以下。1310例患者中痊愈的有1000例，有效的258例，无效的52例。总有效率达96%。

Claims (3)

1.一种治疗肾虚引起的腰膝酸软的中药组合物，其特征在于，所述中药组合物的各个组分及质量份比如下所示：
淫羊藿30～120g、熟地黄120～350g、菟丝子（盐炒）100～160g、山萸肉60～150g、枸杞子50～160g、泽泻60～100g、冬虫夏草30～100g、茯苓100～160g、肉苁蓉100～160g、红景天30～70g、山药150～350g、黄茋100～350g、北沙参50～100g、西红花10～45g、牡丹皮60～150g，辅料：微粉硅胶、微晶纤维素和淀粉适量。
2.根据权利要求1所述的治疗肾虚引起的腰膝酸软的中药组合物，其特征在于，所述中药组合物的各个组分及质量份比如下所示：
淫羊藿36～105g、熟地黄135～310g、菟丝子（盐炒）115～140g、山萸肉70～130g、枸杞子56～140g、泽泻70～90g、冬虫夏草36～90g、茯苓115～140g、肉苁蓉115～140g、红景天36～60g、山药180～310g、黄茋115～310g、北沙参56～90g、西红花12～40g、牡丹皮70～130g，辅料：微粉硅胶、微晶纤维素和淀粉适量。
3.根据权利要求1至2所述的治疗肾虚引起的腰膝酸软的中药组合物，，其特征在于，所述中药组合物的各个组分及质量份比如下所示：
淫羊藿95g、熟地黄280g、菟丝子（盐炒）120g、山萸肉115g、枸杞子120g、泽泻80g、冬虫夏草80g、茯苓120g、肉苁蓉120g、红景天52g、山药280g、黄茋280g、北沙参80g、西红花35g、牡丹皮115g，辅料：微粉硅胶、微晶纤维素和淀粉适量。
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Publication number Priority date Publication date Assignee Title
CN111658720A (zh) * 2020-07-10 2020-09-15 张家口义王堂生物科技有限责任公司 用于养生的中药组合物、养生丸以及制备方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111658720A (zh) * 2020-07-10 2020-09-15 张家口义王堂生物科技有限责任公司 用于养生的中药组合物、养生丸以及制备方法

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