CN108136199A - For the phototherapy apparatus of the treating skin disease of scalp - Google Patents
For the phototherapy apparatus of the treating skin disease of scalp Download PDFInfo
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- CN108136199A CN108136199A CN201680054311.3A CN201680054311A CN108136199A CN 108136199 A CN108136199 A CN 108136199A CN 201680054311 A CN201680054311 A CN 201680054311A CN 108136199 A CN108136199 A CN 108136199A
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- phototherapy apparatus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/0616—Skin treatment other than tanning
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00642—Sensing and controlling the application of energy with feedback, i.e. closed loop control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00791—Temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/03—Automatic limiting or abutting means, e.g. for safety
- A61B2090/033—Abutting means, stops, e.g. abutting on tissue or skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/06—Measuring instruments not otherwise provided for
- A61B2090/061—Measuring instruments not otherwise provided for for measuring dimensions, e.g. length
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/06—Measuring instruments not otherwise provided for
- A61B2090/064—Measuring instruments not otherwise provided for for measuring force, pressure or mechanical tension
- A61B2090/065—Measuring instruments not otherwise provided for for measuring force, pressure or mechanical tension for measuring contact or contact pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/08—Accessories or related features not otherwise provided for
- A61B2090/0804—Counting number of instruments used; Instrument detectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/08—Accessories or related features not otherwise provided for
- A61B2090/0814—Preventing re-use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/063—Radiation therapy using light comprising light transmitting means, e.g. optical fibres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0632—Constructional aspects of the apparatus
- A61N2005/0633—Arrangements for lifting or hinging the frame which supports the light sources
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0635—Radiation therapy using light characterised by the body area to be irradiated
- A61N2005/0643—Applicators, probes irradiating specific body areas in close proximity
- A61N2005/0645—Applicators worn by the patient
- A61N2005/0647—Applicators worn by the patient the applicator adapted to be worn on the head
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/065—Light sources therefor
- A61N2005/0651—Diodes
- A61N2005/0652—Arrays of diodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0662—Visible light
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/0616—Skin treatment other than tanning
- A61N5/0617—Hair treatment
Abstract
Provide the dermopathic modulation phototherapy apparatus for treating scalp.Example devices include the flexible printed circuit board (FPCB) of at least one luminaire of the support with transmitter height.FPCB includes multiple interconnection panels and is limited to the bending region at least some interconnection panels and between them, FPCB to be allowed to be configured to concave shape to cover at least part of the calvarium of patient.At least one photic zone close to FPCB is configured to transmit (for example, incoherent) light emitting generated by least one luminaire.At least one stent is configured to be arranged between FPCB and the scalp of patient, and wherein at least one stent includes the support height more than transmitter height.
Description
The statement of related application
This application claims the power of U.S. Provisional Patent Application Serial No. 62/197,736 submitted on July 28th, 2015
Benefit, the disclosure of which are hereby incorporated by reference in its entirety by reference.
Technical field
This disclosure relates to local skin disorders (such as androgenetic alopecia, acne, psoriasis, skin for phototherapy treatment scalp
Scorching and other health status) device and method.
Background
Androgenetic alopecia is the common alopecia form of male and female.In male, this health status is also referred to as
" male pattern alopecia " or type alopecia (patternhairloss).This alopecia form only just affects the 6000 of estimation in the U.S.
Ten thousand people.Although leading to the risk factors of this health status, researcher is it has been determined that androgenetic takes off still among research
Hair is related with the hormone of referred to as androgen, particularly related with the androgen of referred to as dihydrotestosterone.Androgen water in hair follicle
Flat increase can lead to the shorter more sparse growth of the shortening and hair in natural on-off cycles of hair growth period.Most of males think
Bald head is disagreeable and poignant experience.Although the baldness caused by androgenetic alopecia is in women be not as normal as male
See, but for women alopecia psychological impact often bigger.It is taken off although androgenetic alopecia may not be most of women
The main reason for hair, it is reported that female alopecia can influence about 20,000,000 women of the U.S..
Early stage alopecia can be slowed down or be reversed with drug.The drug of FDA approvals includes minoxidil (minoxidil) and non-
That male amine (finasteride).Other treatment selection includes vitamin A acid joint minoxidil, ketoconazole shampoo and spirolactone.
Late period alopecia case may generate drug therapy drug resistance or ineffective.Many patient's selections carry out operation hair transplant.
The various phototherapy apparatus for solving androgenetic alopecia are developed.The treatment that term " phototherapy " is related to light is used
On the way.Not necessarily for hair growth, various light therapy (e.g., including low-level light therapy (LLLT) and photodynamic therapies
(PDT)) it has disclosed report or claims and the various relevant medical benefits of health are provided, including but not limited to:Treat skin or group
Tissue inflammation;Promote tissue or skin healing or rejuvenate;Enhance wound healing;Pain management;Reduce wrinkle, scar, gestation
Line, varication and spider vein;Improve mood;Treat microorganism infection;Treat hyperbilirubinemia;And treat various tumours
With non-neoplastic conditions or disease.
It is recommended that included by phototherapy to provide the various mechanism for the treatment of benefit:Increase blood circulation (such as it is new by increasing
The formation of capillary);The generation of stimulation collagen;Stimulate the release of atriphos (ATP);Enhance porphyrin generation;Drop
The excitability of low neural system tissue;Stimulate fibroblasts;Increase phagocytic function;Induce fuel factor;Stimulate tissue meat
The protrusion of bud and connective tissue;It reduces inflammation;And stimulate the release of acetylcholine.Phototherapy is also proposed to be used in stimulation cell and generates
Nitric oxide.Nitric oxide production various biological functions include following role:The courier of signal, cytotoxin, anti-apoptotic
Agent, antioxidant and microcirculation conditioning agent.Nitric oxide is considered as to loosen vascular smooth muscle, expansion blood vessel, inhibit blood platelet
Aggregation and the immune response of regulatory T-cell mediation.Nitric oxide is generated by the various kinds of cell type in skin, and
It is formed by amino acid L-arginine to L-citrulline and nitric oxide production conversion, by the enzymatic of nitricoxide synthase (NOS)
Effect mediation.
Be intended for solve alopecia commercially available phototherapy apparatus another example isLaser hair regenerative system is (beautiful
The ApiraScience in the Boca Raton city of state Florida State), utilize two pole of red laser for being operated in 655nm ± 5nm
The combination with light emitting diode is managed to implement the rigid helmet (appearance for being similar to bicycle helmet).It is intended for solving alopecia
Another example of commercially available phototherapy apparatus is TheradomeTMThe LH80Pro helmets (appearance for being similar to bicycle helmet), profit
The laser (the Theradome companies of the Pu Laisendun of California, USA) for being 678nm with 80 peak wavelengths.It is intended to
Another example for solving the commercially available phototherapy apparatus of alopecia isLaser cap (CapillusLLC, Miami,
Florida State, the U.S.), it implements and fits in conventional head covering (such as baseball cap, scarf or nothing with being arranged to
Eaves beanie) below with 650nm work 272 laser diodes rigid cap insertion piece.It is intended for solving alopecia
Other commercially available phototherapy apparatus include laser comb, such asLaser comb be (the Boca Raton city of Fla.
LexingtonInt.LLC).It is various7 to 12 laser that laser comb use is worked with 655nm ± 10nm
Module.
Existing phototherapy apparatus has the limitation for influencing its effectiveness.For many users, rigid helmet-type phototherapy is set
It is standby may be uncomfortable and unsightly, and such equipment may manufacture it is pretty troublesome.For the conventional phototherapy helmet, cap and comb
For son (for example, because they need user mobile and biddability), provided on entire region to be treated it is substantially uniform and/
Or continual covering is also likely to be challenging.Heat management is also likely to be that the conventional phototherapy helmet and cap are of interest.
This field continues to look for improved phototherapy apparatus, can simultaneously be overcome with to provide desired photocurrent versus light intensity and be set with conventional phototherapy
Standby relevant challenge.
It summarizes
All aspects of this disclosure be related to for luminous energy is delivered to patient scalp wearable device and manufacture and make
With the method for this equipment.
In a first aspect, this disclosure relates to for the phototherapy of scalp that light emitting (for example, luminous energy) is delivered to patient to be set
Standby, which includes flexible printed circuit board (FPCB), at least one photic zone (for example, sealant or lens) and multiple
Frame.FPCB includes proximal face, which is supported at least one hair above the proximal face with transmitter height
Light device, wherein, FPCB includes multiple interconnection panels and multiple bending regions, and multiple bending region is limited at the multiple
So that FPCB is allowed to provide concave shape to cover the calvarium of patient at least between the neutralization of at least some of interconnection panel
A part.At least one photic zone is arranged in FPCB nearby and is configured as transmiting what is generated by least one luminaire
At least some light emittings.The multiple stent is configured to be arranged between FPCB and the scalp of patient, in plurality of stent
At least some stents include more than transmitter height support height.
In certain embodiments, phototherapy apparatus further includes drive circuit, which is configured as excitation at least
One luminaire is to generate light emitting.In certain embodiments, at least one luminaire includes multiple luminaires.
In certain embodiments, phototherapy apparatus further includes formed parts, which, which has, is arranged to receive FPCB's
Generally concave inside.In certain embodiments, phototherapy apparatus further includes the fabric cover for being arranged over FPCB.Certain
In embodiment, FPCB is arranged to the scalp for adapting to expand outwardly and allowing multiple stent contact patients to contract.At certain
In a little embodiments, phototherapy apparatus further includes the fabric cap being located near the distal surface of FPCB, and wherein fabric cap defines hole,
The hole is configured to receive at least part of electric-device housing for including drive circuit.
In certain embodiments, phototherapy apparatus further includes the energy storage device for being electrically coupled to drive circuit.Certain
In embodiment, energy storage device includes battery, and battery is kept by the battery holder for being coupled to electric-device housing.
In certain embodiments, phototherapy apparatus further includes power circuit, and it is at least one which is arranged to offer
Power signal after the adjustment, for the use of at least one of the microcontroller of phototherapy apparatus or at least one luminaire, wherein,
In the access times specified for detecting phototherapy apparatus, which is instructed to prevent the further operating of phototherapy apparatus.
In certain embodiments, phototherapy apparatus is configured to the disabling signal that generation is adapted to irreversibly disable power circuit.
In some embodiments, power circuit includes being arranged to connect at least one fuse that at least one luminaire is electrically connected, and
And disabling signal is adapted to disconnect at least one fuse connection so that electric current to be prevented to be supplied at least one luminaire.
In certain embodiments, at least one luminaire is made of incoherent luminaire.In certain embodiments, when
When being energized to shine, which provides the energy density (fluence) of at least erg-ten every square centimeter.
In certain embodiments, at least one luminaire, which includes being arranged to, generates first of the light with the first peak wavelength
Luminaire array and the second luminaire array for being arranged to light of the generation with the second peak wavelength, wherein, the second peak
Value wavelength differs at least 20nm with the first peak wavelength.
In certain embodiments, the first peak wavelength and the second peak wavelength are selected from one of following combination (a) to (f):(a)
First peak wavelength is in the range of 615nm to 635nm, and the second peak wavelength is in the range of 650nm to 670nm;(b)
One peak wavelength is in the range of 520nm to 540nm, and the second peak wavelength is in the range of 650nm to 670nm;(c) first
Peak wavelength is in the range of 410nm to 430nm, and the second peak wavelength is in the range of 620nm to 640nm;(d) first peak
It is worth wavelength in the range of 410nm to 430nm, and the second peak wavelength is in the range of 650nm to 670nm;(e) the first peak value
Wavelength is in the range of 410nm to 430nm, and the second peak wavelength is in the range of 495nm to 515nm;Or (f) first peak value
Wavelength is in the range of 410nm to 430nm, and the second peak wavelength is in the range of 520nm to 540nm.
In certain embodiments, at least one luminaire, which includes being arranged to, generates the light with the first peak wavelength
First luminaire array and the second luminaire array for being arranged to light of the generation with the second peak wavelength, and second
Peak wavelength differs at least 50nm with the first peak wavelength.
In certain embodiments, the first luminaire array, which provides, has the first peak wavelength value and the first full width at half maximum value
Spectrum output, wherein the first peak wavelength value subtract the first full width at half maximum value half be more than 400 nanometers;And second shines
Equipment array provides the spectrum output with the second peak wavelength value and the second full width at half maximum value, wherein second peak wavelength
The half that value subtracts the second full width at half maximum value is more than 450 nanometers.
In certain embodiments, phototherapy apparatus further includes proximity sensor, which indicates light into sensing
Equipment is treated close to the situation of the placement of the scalp of patient, startup, termination or the modification of the operation of wherein at least one luminaire
At least one of be in response to output signal in proximity sensor.
In certain embodiments, phototherapy apparatus further includes temperature sensor, which is arranged to sensing in phototherapy
Temperature regime in a part for equipment or near it, the startup of the operation of wherein at least one luminaire, the deviation of operation
Or at least one of termination of operation is in response to the output signal in temperature sensor.
In certain embodiments, phototherapy apparatus further includes:(a) the appreciable optical signal element of user, is arranged to
Generate optical signal;And/or the appreciable earcon element of (b) user, it is arranged to generation earcon, wherein, it can
Depending on mode of operation, the charged state of phototherapy apparatus or the operation of phototherapy apparatus of signal and/or earcon instruction phototherapy apparatus
The counting in period.
In certain embodiments, multiple stents are combined at least one photic zone.In certain embodiments, it is multiple
Stent is attached at least one photic zone.
In certain embodiments, phototherapy apparatus is embodied in the wearable cap for being arranged to and being worn on patients head,
Wherein, the outmost surface of wearable cap includes fabric cover.
In certain embodiments, from the proximal end of at least some of multiple stents stent to the distance of the proximal face of FPCB
More than at least one euphotic thickness.In certain embodiments, multiple stents are between FPCB and at least one photic zone.
In certain embodiments, at least one photic zone includes flexible biconvex lens (flexible lenticular lens).
In certain embodiments, include phototherapy apparatus being placed on patient's for treating at least one dermopathic method
Head, and encourage at least one luminaire light emitting is radiated at least part of the scalp of patient.
On the other hand, this disclosure relates to for light emitting to be delivered to the phototherapy apparatus of the scalp of patient.Phototherapy apparatus packet
Flexible substrate is included, which includes supporting the proximal face of at least one luminaire array and be configured to transmission by least
At least some photoemissive photic zones that one luminaire array generates.The equipment, which further includes, is positioned in flexible substrate and trouble
Multiple stents between the scalp of person.The equipment further includes energy storage elements, is arranged to what is be electrically connected with energy storage elements
And it is configured to the drive circuit for driving at least one luminaire array and the fabric for being arranged over flexible substrate
Covering.Flexible substrate and fabric cover are arranged to adaptation and expand outwardly and to contract, to allow phototherapy apparatus adjustable
Site preparation fits to the head of patient.
In certain embodiments, from the proximal end of at least some of multiple stents stent to the proximal face of flexible substrate
Distance is more than euphotic thickness.In certain embodiments, multiple stents are located between flexible substrate and photic zone.At certain
In a little embodiments, photic zone includes flexible biconvex lens.
In certain embodiments, flexible substrate includes multiple interconnection panels and including multiple bending regions, multiple bending
Region is limited between the neutralization of at least some of multiple interconnection panels panel.
In certain embodiments, flexible substrate includes flexible printed circuit board (FPCB).In certain embodiments, at least one
Luminaire in a luminaire array includes transmitter height, and phototherapy apparatus includes being arranged on FPCB and/or light transmission
Multiple stents on layer, multiple stents are raised relative to proximal face, wherein, at least some of multiple stents stent includes
More than the support height of transmitter height.
In certain embodiments, gap is provided between the part of the adjacent panels in multiple interconnection panels to adapt to outward
It expands and to contract, and the heat generated by least one luminaire array can be distributed.
In certain embodiments, phototherapy apparatus further includes the fabric cap for limiting hole, which is configured to receive comprising driving
At least part of electric-device housing of device circuit.In certain embodiments, energy storage elements include battery, and battery
It is fixed to electric-device housing or the battery holder by being pivotally coupled to electric-device housing is kept.
In certain embodiments, in the access times specified for detecting phototherapy apparatus, phototherapy apparatus is additionally configured to
Generation is adapted to irreversibly disable the disabling signal of phototherapy apparatus, to prevent the further operating of phototherapy apparatus.Certain
In embodiment, disabling signal includes due to voltage spikes and/or current spike.
In certain embodiments, phototherapy apparatus further includes power circuit, which is arranged to offer and is set by phototherapy
At least one power signal after the adjustment that standby microcontroller and/or at least one luminaire array use, wherein, disabling letter
Number sent further operating to prevent phototherapy apparatus.
In certain embodiments, phototherapy apparatus, which further includes, is arranged to be electrically connected at least at least one luminaire array
One fuse connection, wherein disabling signal is adapted to disconnect at least one fuse connection, electric current to be prevented to be provided to this extremely
A few luminaire array.
In certain embodiments, at least one luminaire array is made of incoherent solid luminous device.In certain realities
It applies in example, at least one solid luminous device array provides the energy density of at least erg-ten every square centimeter.In some embodiments
In, at least one solid luminous device array includes being arranged to the first solid luminescent for generating the light with the first peak wavelength
Equipment array and the second solid luminous device array for being arranged to generate the light with the second peak wavelength, and the second peak value wave
It is long to differ at least 20nm with the first peak wavelength.
In certain embodiments, the first peak wavelength and the second peak wavelength are selected from one of following combination (a) to (f):(a)
First peak wavelength is in the range of 615nm to 635nm, and the second peak wavelength is in the range of 650nm to 670nm;(b)
One peak wavelength is in the range of 520nm to 540nm, and the second peak wavelength is in the range of 650nm to 670nm;(c) first
Peak wavelength is in the range of 410nm to 430nm, and the second peak wavelength is in the range of 620nm to 640nm;(d) first peak
It is worth wavelength in the range of 410nm to 430nm, and the second peak wavelength is in the range of 650nm to 670nm;(e) the first peak value
Wavelength is in the range of 410nm to 430nm, and the second peak wavelength is in the range of 495nm to 515nm;Or (f) first peak value
Wavelength is in the range of 410nm to 430nm, and the second peak wavelength is in the range of 520nm to 540nm.
In certain embodiments, at least one solid luminous device array includes being arranged to generation with the first peak value wave
First solid luminous device array of long light is set with the second solid luminescent for being arranged to generate the light with the second peak wavelength
Standby array, and the second peak wavelength differs at least 50nm with the first peak wavelength.
In certain embodiments, the first solid luminous device array provides complete with the first peak wavelength value and the first half-peak
The spectrum output of width values, wherein, the half that the first peak wavelength value subtracts the first full width at half maximum value is more than 400 nanometers;And the
Two solid luminous device arrays provide the spectrum output with the second peak wavelength value and the second full width at half maximum value, wherein, second
The half that peak wavelength value subtracts the second full width at half maximum value is more than 450 nanometers.
In certain embodiments, phototherapy apparatus further includes optical sensor, which is arranged to sensing instruction
Phototherapy apparatus is placed on the situation near the scalp of patient, wherein, the startup of the operation of at least one luminaire array terminates
And/or modification is in response to the output signal in optical sensor.
In certain embodiments, phototherapy apparatus further includes temperature sensor, which is arranged to sensing in phototherapy
In a part for equipment or neighbouring temperature regime, wherein, the startup of the operation of at least one luminaire array, operation
The termination of modification and/or operation is in response in the output signal of temperature sensor.
In certain embodiments, phototherapy apparatus further includes:(a) the appreciable optical signal element of user, is arranged to produce
Raw optical signal;And/or the appreciable earcon element of (b) user, it is arranged to generate earcon, wherein, visually
The mode of operation of signal and/or earcon instruction phototherapy apparatus, the charged state of phototherapy apparatus or the operation week of phototherapy apparatus
The counting of phase.
In certain embodiments, phototherapy apparatus further includes:(a) the appreciable optical signal element of user, is arranged to produce
Raw optical signal;And/or the appreciable earcon element of (b) user, it is arranged to generate earcon, wherein visual letter
Number and/or earcon instruction phototherapy apparatus operation cycle counting.
In certain embodiments, phototherapy apparatus is implemented in the wearable cap on the head for being arranged to and being worn on patient
In, wherein, the outmost surface of wearable cap includes fabric cover.
In certain embodiments, include phototherapy apparatus being placed on patient's for treating at least one dermopathic method
On head, and at least one luminaire array is encouraged to be radiated at luminous energy at least part of the scalp of patient.
In another aspect, this disclosure relates to for treating at least one dermopathic method, the method includes will be as
Phototherapy apparatus disclosed herein is placed on the head of patient, and at least one luminaire array is encouraged to be radiated at luminous energy
In at least part of the scalp of patient.
On the other hand, this disclosure relates to for light emitting to be delivered to the phototherapy apparatus of the scalp of patient.The equipment includes
Flexible lens, flexible lens include proximal lens surface and distal lens surface;Flexible printed circuit board (FPCB), the flexibility
Printed circuit board is included at least one luminaire in its proximal face;And multiple stents, the multiple stent are determined
Position is between the distal lens surface and the FPCB between at least one luminaire and the distal lens surface
Keep minimum range.Phototherapy apparatus is configured as transmiting the light emitting generated by least one luminaire by flexible lens
To the scalp of patient.
In certain embodiments, from the proximal end of each stent in the multiple stent to the proximal face of flexible lens
Distance is more than the thickness of flexible lens.In certain embodiments, photic zone includes flexible biconvex lens.
In certain embodiments, phototherapy apparatus further includes communication module, is configured as and the electronics outside phototherapy apparatus
Equipment carries out electronic communication.
In certain embodiments, the light emitting of at least one luminaire is about in the range of 410nm to 455nm
It is interior.In certain embodiments, the light emitting of at least one luminaire about exists in the range of 620nm to 700nm or about
In the range of 620nm to 900nm.In certain embodiments, light emitting is configured to treat or prevent the alopecia of patient.
In certain embodiments, include phototherapy apparatus being placed on patient's for treating at least one dermopathic method
On head, and encourage at least one luminaire light emitting is delivered at least part of the scalp of patient.
In certain embodiments, phototherapy apparatus further includes drive circuit, which is configured as excitation at least
One luminaire is to generate light emitting.In certain embodiments, at least one luminaire includes multiple luminaires.
In certain embodiments, phototherapy apparatus further includes fabric cap, and wherein FPCB is located in fabric cap and flexible lens
Between, and FPCB includes expansion joint to allow the aperture perimeter of adjustment fabric cap.In certain embodiments, fabric cap limits
It is configured to receive the hole of at least part of electric-device housing comprising drive circuit.In certain embodiments, FPCB
It is arranged to adaptation to expand outwardly and to contract.
In certain embodiments, phototherapy apparatus further includes the energy storage device for being electrically coupled to drive circuit, wherein, energy
It measures storage device and includes battery, and battery is kept by the battery holder for being coupled to electric-device housing.
In certain embodiments, phototherapy apparatus further includes power circuit, which is arranged to provide at least one
Power signal after the adjustment, for the use of at least one of the microcontroller of phototherapy apparatus or at least one luminaire, wherein,
Disabling signal is adapted to irreversibly disable power circuit.
In certain embodiments, multiple stents are combined with flexible lens.In certain embodiments, multiple stents are attached
It is connected to flexible lens.
In certain embodiments, phototherapy apparatus includes substrate, which includes multiple interconnection panels and multiple bending regions,
The multiple bending region is limited between the neutralization of multiple panels in multiple interconnection panels.
In certain embodiments, in the access times specified for detecting phototherapy apparatus, phototherapy apparatus is additionally configured to
Generation is adapted to irreversibly disable the disabling signal of phototherapy apparatus, to prevent the further operating of phototherapy apparatus.Certain
In embodiment, disabling signal includes due to voltage spikes and/or current spike.
In certain embodiments, phototherapy apparatus, which further includes, is arranged as at least one luminaire (for example, at least one hair
Light device array) at least one fuse connection for being electrically connected, wherein, disabling signal is adapted to disconnect at least one fuse connection
Electric current to be prevented to be supplied at least one luminaire.
In certain embodiments, phototherapy apparatus further includes optical sensor, and the optical sensor is arranged to sensing and refers to
Show that the phototherapy apparatus is placed on the situation near the scalp of patient, wherein, at least one luminaire is (for example, at least
One array of light emitting devices) at least one of startup, termination or the modification of operation be in response to output in optical sensor
Signal.
In certain embodiments, phototherapy apparatus further includes temperature sensor, which is arranged to sensing in light
In a part for equipment or neighbouring temperature regime is treated, wherein, at least one luminaire is (for example, at least one hair
Light device array) startup, the modification of operation or at least one of the termination of operation of operation be in response in temperature sensor
Output signal.
In certain embodiments, flexible lens include flexible biconvex lens.In certain embodiments, multiple stents are integrally
It is attached to flexible biconvex lens.In certain embodiments, flexible lens and FPCB be in size and/or shape it is adjustable with
Adapt to various head sizes.In certain embodiments, flexible biconvex lens and multiple stents are formed by moulding.
In another aspect, this disclosure relates to a kind of phototherapy apparatus for the scalp for being used to luminous energy being delivered to patient.Phototherapy
Equipment includes fabric cap, including the flexible biconvex lens of multiple stents that extend from its distal surface and is positioned in flexible pair
Between convex lens and fabric cap flexible printed circuit board (FPCB) (FPCB include limit recess portion multiple interconnection panels) and
It is arranged at least one luminaire that is in the proximal face of FPCB and being configurable to generate incoherent light.Multiple stent quilts
It is configured to the interval of the minimum range between the distal surface for maintaining at least one luminaire and flexible biconvex lens.Phototherapy
Equipment is configured as being worn on to cover at least part of the calvarium of patient on the head of patient, to transmit by least one hair
At least part of the incoherent light of light device generation is to be radiated on the scalp of patient.In another aspect, this disclosure relates to
A kind of method for the scalp that luminous energy is delivered to patient.This method includes the above-head that phototherapy apparatus is located in patient, light
Equipment is treated to include the flexible lens with distal lens surface, cover flexible lens at least partly and support at least one hair
The flexible printed circuit board (FPCB) of light device and be positioned between the distal lens surface and the FPCB with maintain
Multiple stents of minimum range between at least one luminaire and the distal lens surface;Adjust phototherapy apparatus
Size and/or shape to be bonded the head of patient;From at least one luminaire generation light for being installed to the FPCB
Transmitting;And by photoemissive at least part that the transmission of at least one light transmission parts of the flexible lens is generated to shine
It penetrates on the scalp of patient.
In another aspect, this disclosure relates to assemble the method for phototherapy apparatus.This method is included in flexible lens at least
A part of top placement of flexible printed circuit board (FPCB), the FPCB include at least one luminaire being mounted thereon,
Plurality of stent is positioned between distal lens surface and FPCB at least one luminaire and the distal side
Minimum range is kept between lens surface and fabric cap is arranged in above at least part of the FPCB, wherein described
FPCB is fixed between the fabric cap and the flexible lens.
In another aspect, this disclosure relates to a kind of capacitor.The capacitor includes:First flexible circuit panel element,
Including the first conductive material layer and the first dielectric material layer;Second flexible circuit panel element, including the second conductive material layer
With the second dielectric material layer;And at least one solid spacer, it is connected in the first flexible circuit panel element and second soft
Between property circuit board component.
In certain embodiments, at least one solid spacer has dielectric constant values, and the dielectric constant values are about 2
To in the range of about 5.In certain embodiments, at least one solid spacer is adhered to the first flexible circuit panel element and second
Between flexible circuit panel element.
In certain embodiments, the first flexible circuit panel element is extended continuously portion including the second flexible circuit panel element
Point, there is the recurvate flexure area being disposed between the first flexible circuit panel element and the second flexible circuit panel element
Domain.In certain embodiments, the first conductive material layer has the extending transversely of bigger than the second conductive material layer.
In certain embodiments, at least one solid spacer, the first dielectric material layer and the second dielectric material layer
Distance between the first conductive material layer and the second conductive material layer is maintained in the range of about 0.2mm to about 2mm.At certain
In a little embodiments, the distance is in the range of about 0.3mm to about 1.9mm.
In certain embodiments, proximity sensor includes capacitor.
In another aspect, any in terms of foregoing as described herein and/or various individual aspect and feature can be combined
To obtain additional advantage.Any feature and element in various features disclosed herein and element can with it is one or more its
Feature disclosed in him and element combination, unless opposite instruction herein.
From subsequent disclosure and appended claims, other aspects of the invention, feature and embodiment will more fill
It is clearly demarcated aobvious.
Brief description
Fig. 1 is implemented in be regarded for delivering the decomposition of the luminaire in photoemissive wearable cap to the scalp of patient
Figure, the equipment include multiple photophores of the FPCB being configured by arrangement concavity supports and stent, are configured to receive and FPCB and match
It is set to the spill formed parts of support battery and control module and is arranged over supporting member and the fabric of flexible substrate covers
Cover material.
Fig. 2A is the perspective upper view of spill formed parts combined with the control module of Fig. 1 (charged pool).
Fig. 2 B are the spill formed parts of Fig. 2A and the top plan view of control module.
Fig. 2 C are the spill formed parts of Fig. 2A and 2B and the front view of control module.
Fig. 2 D are the spill formed parts of Fig. 2A -2C and the left side view of control module.
Fig. 2 E are the spill formed parts of Fig. 2A -2D and the lower perspective view of control module.
Fig. 2 F are the spill formed parts of Fig. 2A -2E and the bottom plan view of control module (charged pool).
Fig. 3 A are the bottom plan views of the FPCB shown in Fig. 1, before FPCB to be configured to spill configuration, the FPCB
With the photophore and stent being disposed thereon.
Fig. 3 B are the bottom plan views of the FPCB of Fig. 3 A, installation photophore and formed stent before and FPCB into
Before shape, which has the electric trace being disposed thereon and transmitter installation region.
Fig. 3 C are the electric marks that the top side along FPCB is shown from the viewgraph of cross-section of the FPCB of Fig. 3 A and 3B in terms of bottom
Line.
Fig. 3 D are the bottom plan views of the FPCB profiles of Fig. 3 A-3C, show FPCB being configured to concave shape
To be bonded bending region and the bending angle around the scalp of user.
Fig. 3 E are that concave shape, Fig. 3 D being suitable for around the scalp of fitting user are formed after bending or forming step
FPCB perspective upper view.
Fig. 3 F are the lower flat views of the forming FPCB of Fig. 3 E, wherein for convenience of description, there is no transmitter, marks
Line, transmitter installation region or stent.
Fig. 3 G are the left side view of the forming FPCB of Fig. 3 E and 3F.
Fig. 3 H are the top front face perspective views of the forming FPCB of Fig. 3 E-3G.
Fig. 4 A are the perspective upper views of the luminaire of the assembling in Fig. 1.
Fig. 4 B are the top plan views of the luminaire of the assembling in Fig. 4 A.
Fig. 4 C are the front views of the luminaire of the assembling of Fig. 4 A and 4B.
Fig. 4 D are the left side views of the luminaire assembled in Fig. 4 A-4C.
Fig. 5 A are the front views for the luminaire for being superimposed upon assembling above simulation human head, in Fig. 4 A-4D.
Fig. 5 B are the side views of a part for the luminaire in Fig. 1,4A-4D and 5A, be omitted spill formed parts and
Fabric cover.
Fig. 6 is the schematic views for the fabric cover for including adjustable closure member, which is arranged to fair
Perhaps the aperture perimeter of fabric cover is adjusted.
Fig. 7 A are the side sectional views of a part for the first luminaire, which includes having more from supporting
The stent of the circular structure being bent upwards of the FPCB extensions of the encapsulation of a light-emitting component.
Fig. 7 B are the side sectional views of a part for the second luminaire, which includes having more from supporting
The stent of the round column structure of the FPCB extensions of the encapsulation of a light-emitting component.
Fig. 7 C are the side sectional views of a part for third luminaire, which includes having more from supporting
The stent of the taper column structure of the FPCB extensions of the encapsulation of a light-emitting component.
Fig. 7 D are the side sectional views of a part for the 4th luminaire, and the 4th luminaire includes having more from supporting
The stent of the concave cone construction of the FPCB extensions of the encapsulation of a light-emitting component.
Fig. 7 E are the side sectional views of a part for the 5th luminaire, and the 5th luminaire includes having more from supporting
The stent of the flat addendum cone construction of the FPCB extensions of the encapsulation of a light-emitting component.
Fig. 7 F are the side sectional views of a part for the 6th luminaire, and the 6th luminaire includes having more from supporting
The stent of the circular structure of the FPCB extensions of the encapsulation of a light-emitting component.
Fig. 8 is to show to be used between the component of the luminaire of the scalp delivering luminous energy of patient according to one embodiment
Interconnection schematic diagram.
Fig. 9 is to describe being suitable for operating and set for luminous energy to be delivered to the luminous of scalp of patient according to one embodiment
The schematic diagram of interface between standby hardware driver, functional unit and software application.
Figure 10 A are being embodied in for into the wearable cap of the scalp of patient delivering luminous energy according to one embodiment
For the perspective upper view of the luminaire of phototherapy, phototherapy apparatus includes flexible cap, has at least one luminaire (LED)
Flexible printed circuit board (FPCB), flexible biconvex lens and multiple stents.
Figure 10 B are the lower perspective views of the phototherapy apparatus of Figure 10 A.
Figure 10 C are the right side views of the phototherapy apparatus of Figure 10 A and 10B.
Figure 10 D are the bottom plan views of the phototherapy apparatus of Figure 10 A-10C.
Figure 10 E are the decomposition views of the phototherapy apparatus of Figure 10 A-10D.
Figure 11 A are the rearviews of flexible printed circuit board (FPCB) component shown in Figure 10 E, and FPCB components include panel
Sub-component and electronic device sub-component.
Figure 11 B are the side sectional views intercepted along the section line AA shown in Figure 11 A of the FPCB components in Figure 11 A.
Figure 11 C are the decomposition views of the FPCB components of Figure 11 A and 11B.
Figure 12 A are the bottom perspective views of the panel sub-component in curved configuration, Figure 11 A, wherein between various panels
Bending is formed to form recess portion.
Figure 12 B are the bottom plan views of the panel sub-component in curved configuration, Figure 12 A.
Figure 12 C are along the face in taken through section line C-C, curved configuration, Figure 12 A and Figure 12 B shown in Figure 12 B
The side cross-sectional side view of plank component.
Figure 12 D are the top plan views of the panel sub-component in flat configuration, Figure 12 A-12C, and plate is shown
Between be bent region.
Figure 12 E be flat configuration, Figure 12 A-12D panel sub-component bottom plan view.
Figure 12 F are comprising for the manufacture capacitor before folding printed circuit board (FPCB) and adherency capacitor element
The viewgraph of cross-section of the flexible FPCB of element.
Figure 12 G be by the FPCB shown in Figure 12 F and the capacitor of element manufacture (including flexible printed circuit board element and
Spacer element between) viewgraph of cross-section (along the taken through section line B-B in Figure 12 F).
Figure 12 H are the circuit diagrams for including IC chip and the proximity sensor according to the capacitor of Figure 12 G.
Figure 13 A are the front views for the patient for wearing the phototherapy apparatus according to Figure 10 A-10E.
Figure 13 B are along the transversal of the patient in taken through section line B-B, Figure 13 A shown in Figure 13 A and phototherapy apparatus
Surface side view.
Figure 14 A are the perspective upper views of the packaging comprising the phototherapy apparatus according to Figure 10 A-10E.
Figure 14 B are packaging after head cover is removed from the bottom cover of packaging, in Figure 14 A and the exploded perspective of phototherapy apparatus
Figure.
Figure 14 C are the decomposition views according to one embodiment, the packaging of the phototherapy apparatus with Figure 14 A and Figure 14 B.
The side sectional view for the phototherapy apparatus that Figure 14 D have been the packagings of Figure 14 A-14C.
The perspective upper view of the charging base part for the phototherapy apparatus that Figure 15 A have been the packagings of Figure 14 A-14D.
Figure 15 B are the lower perspective views of the charging base of Figure 15 A.
Figure 15 C are the side views of the charging base of Figure 15 A and 15B.
Figure 15 D are the top plan views of the charging base of Figure 15 A-15C.
Detailed description
Embodiments set forth below expression enables those skilled in the art to put into practice the necessary information of embodiment, and show
Put into practice the optimal mode of embodiment.After reading is described below with reference to the accompanying drawings, it should be appreciated by those skilled in the art that the disclosure
Concept and the application that will be recognized that these concepts that not should be particularly mentioned that herein.It should be understood that these concepts and application fall into this
In open and scope of the appended claims.
It should be understood that although term " first ", " second " etc. are possibly used for describing each element herein, these elements
It should not be limited by these terms.These terms are used only to distinguish an element with another.For example, not departing from this public affairs
In the case of the range opened, first element can be referred to as second element, moreover, similarly, second element can be referred to as
One element.As it is used herein, term "and/or" includes one or more arbitrary groups in associated listed item
Conjunction and all combinations.
It should be understood that when element is referred to as being "connected" or "coupled" to another element, it can be connected directly
Or it is coupled to another element or there may be elements between.On the contrary, be referred to as being " directly connected " when element or
When " direct-coupling " is to another element, there is no elements between.
It should be understood that although term " top ", " lower part ", " bottom ", " centre ", " middle part ", " top " etc. can in this paper
For describing each element, but these elements should not be limited by these terms.These terms be used only to by an element with it is another
One distinguishes.For example, without departing from the scope of the disclosure, first element can be referred to as " top " element, and
And similarly, second element can be referred to as " top " element, this depends on the relative direction of these elements.
The term as used herein is intended merely to description specific embodiment, is not intended to the limitation disclosure.As herein
It is used, singulative " one (a) ", " one (an) " and " (the) " are also intended to including plural form, unless context is another
It clearly indicates.It will further be understood that term " including (comprises) ", " including (comprising) ", " including
(includes) " and/or " including (including) " herein in use, enumerating stated feature, integer, step, behaviour
The presence of work, element and/or component, but do not preclude the presence or addition of one or more of the other feature, integer, step, operation, member
Part, component and/or their group.
Unless otherwise defined, all terms (including technical and scientific term) used herein have disclosure fields
The normally understood equivalent of those of ordinary skill.It will further be understood that term as used herein should be interpreted have
Have the meaning consistent with their meanings under the background of this specification and related field and will not be interpreted as it is Utopian or
The meaning excessively formalized, unless clearly definition so herein.
All aspects of this disclosure be related to for luminous energy is delivered to patient scalp wearable device and manufacture and make
With the method for this equipment.
Various embodiments disclosed herein includes supporting the flexible printed circuit board (FPCB) of at least one luminaire.
In some embodiments, FPCB can include layer and at least one layer of copper or another conductive material containing polyimides.In certain realities
Apply in example, can arrange photic zone (for example, sealant or lens) with cover and/or be arranged to at least part of FPCB and
Any photophore contact being supported on.Preferred sealant material is silicones, can pass through any suitable means
(such as molding, dipping, spraying, distribution (dispensing), printing etc.) applies.In certain embodiments, FPCB's is basic
Upper all surfaces (for example, front surface and rear surface) can be covered with sealant material.In certain embodiments, including embedded
The overall thickness of the flexible LED of the encapsulation of photophore can be in the range of 1mm to 5mm or in the range of 1mm to 3mm, no
Including stent.In certain embodiments, FPCB includes flexible polymeric film, polyester (PET), polyimides (PI), poly- naphthalene diformazan
Sour glycol ester (PEN), polyetherimide (PEI), fluoropolymer (FEP), copolymer etc..
In certain embodiments, at least one stent is configured to be arranged between FPCB and the scalp of patient, and extremely
A few stent includes support height, which is more than the height by the FPCB transmitters supported.Preferably, it is at least one
Stent includes the translucent material of such as silicones, PET, PET-G etc..
In certain embodiments, the step of forming the FPCB for having standoff encapsulation, which can be included on FPCB, limits electric mark
Line;It installed on FPCB, formed or otherwise fix one or more light-emitting components, form stent or holder part;
And it encapsulates and includes light-emitting component, the various structures of FPCB and optionally package support or holder part.In some embodiments
In, thus it is possible to vary the sequence of abovementioned steps, and in certain embodiments, at least some stents can partly or entirely be free of
Sealant.
In certain embodiments, stent or holder part can be molded, place, formed, print, adhere to before encapsulation
Or be otherwise applied on the face of FPCB, and stent or holder part then can partially or even wholly with one or
One or more partial encapsulations of more each light-emitting components and FPCB are together.
In certain embodiments, after FPCB and light-emitting component have been packaged, stent or holder part can be placed,
It is formed, printed, adhered to or is otherwise applied on the face of FPCB.
In certain embodiments, stent or holder part can with packaging technology (such as by mould, print, spray or its
His deposition method) it is formed simultaneously.
In certain embodiments, crosslinkable materials can apply or be formed selectively along the region of FPCB, and this
The material of sample can by appropriate means (for example, heat, photon energy, chemokinesis etc.) before the packaging step, among or
It is activated to form stent or holder part later.
In certain embodiments, support height, stent shape, light-emitting component interval and optical element optical profile can be chosen
It is selected to that adjacent light-emitting component is allowed to provide overlapping bundles of rays pattern on the scalp of patient.
In certain embodiments, the array of multiple stents can be formed on sealant material, in sealant material or
Above sealant material.In certain embodiments, each stent in array have essentially identical size, shape and/or
Hardness.In other embodiments, the different support in array can include different sizes, shape and/or hardness.
In certain embodiments, one or more stents can include suitable shape and/or material is gathered with providing light
Burnt effectiveness, light diffusion effectiveness and/or light scattering effectiveness.In certain embodiments, one or more stents can include one kind
Or more kind wavelength conversion material (such as fluorophor, quantum dot, fluorogen etc.) and provide wavelength convert effectiveness.In certain implementations
In example, one or more stents can include suitable shape and/or material to provide light reflection effectiveness.
In certain embodiments, one or more stents can be placed with and one or more light-emitting components point
It opens.In other embodiments, one or more stents can be strategically placed on one or more light-emitting components or
Its top, stent are used to transmiting, shape and/or otherwise influencing the light received from one or more light-emitting components.
Various types of light-emitting components can be used together with phototherapy apparatus, for luminous energy to be delivered to the head of patient
Skin.In certain embodiments, the transmitting of phototherapy apparatus can be made of incoherent light (for example, the spy of light emitting diode transmitting
Sign).In certain embodiments, the transmitting of phototherapy apparatus can be made of (for example, feature of Laser emission) coherent light.Certain
In embodiment, the transmitting of phototherapy apparatus can include the combination of coherent light and incoherent light.In certain embodiments, phototherapy apparatus
Any laser diode not being arranged on the scalp for light shining patient.
In certain embodiments, for luminous energy is delivered to the phototherapy apparatus of the scalp of patient can include it is one or more
A solid luminous device.The example of solid luminous device includes but is not limited to light emitting diode, laser, thin film electroluminescence
Equipment, powder electroluminescence equipment, field cause responsive polymer electroluminescence device and macromolecular LED electrochemical cell.
In certain embodiments, multiple transmitters with different peak wavelengths (for example, with difference at least about 10nm,
The peak of at least about 20nm, at least about 30nm, at least about 50nm, at least about 75nm, about 100nm or another threshold value specified herein
Value wavelength) it can be provided.
In certain embodiments, the light of different peak wavelengths can be packed by being included in single (for example, solid-state) transmitter
In different transmitters generation, wherein the tight spacing between adjacent transmitter can provide integral color mixing.In certain realities
It applies in example, one or more luminaire arrays can be provided.In certain embodiments, the first luminaire array can be by
It is configured to provide the light of the first peak wavelength, and the second luminaire array may be configured to provide the second peak wavelength
Light.In some embodiments it is possible to provide the array of multi-emitter packaging, the wherein transmitter in individual packaging can provide phase
Same or different peak wavelength.In certain embodiments, the array of soild state transmitter packaging can implement to further include second, third,
The packaging of 4th and/or the 5th soild state transmitter so that the single array of soild state transmitter packaging can implement soild state transmitter
Two, three, four or five arrays, wherein each array is arranged to transmitting of the generation with different peak wavelengths.
In certain embodiments, can include turning without wavelength for luminous energy to be delivered to the phototherapy apparatus of the scalp of patient
One or more luminaires of conversion materials.In other embodiments, one or more luminaires can be arranged to
Stimulate wavelength conversion material, such as phosphor material, fluorescent dye materials, quanta point material and fluorescent material.
In certain embodiments, one or more luminaires can be arranged to provide substantially monochromatic light.
In some embodiments, one or more luminaires can include having full width at half maximum value be less than 25nm (or less than 20nm or
Less than 15nm or in the range of 5nm to 25nm or in the range of 10nm to 25nm or in the range of 15nm to 25nm)
Spectrum output.
In some embodiments, one or more luminaires can be arranged to offer and have in 400nm extremely
In the range of 900nm or in the range of 500nm to 900nm or in the range of 500nm to 800nm or in 600nm extremely
Peak wavelength in the range of 700nm or in the range of 620nm to 670nm.
In certain embodiments, at least one luminaire can be arranged to offer have 620nm to 645nm (or
From 615nm to 635nm) in the range of peak wavelength transmitting, and it is at least one transmitting equipment offer tool can be provided
There is the transmitting of the peak wavelength in the range of 645nm to 670nm (or 650nm to 670nm).In certain embodiments, at least one
A first luminaire can be arranged to the transmitting for providing the peak wavelength with about 630nm, and at least one second hair
Light device can be arranged to the transmitting for providing the peak wavelength with about 660nm.Such wavelength potentially contributes to provide anti-
Inflammation effect and/or promotion vasodilation.Anti-inflammatory effect can be used for promoting wound healing, reduce acne blemish, promote face esthetic,
And/or treat atopic dermatitis and other local skin disorders.Vasodilation may also be beneficial to treat androgenetic alopecia or its
His local skin disorders.
In certain embodiments, at least one luminaire (or multiple luminaires) can be configured as generation in wavelength
Bacterium in the living mammalian tissue for receiving light or thereon or other microorganisms can be changed in terms of range and flux
In the presence of, aggregation or growth light.UV light and nearly UV light (such as with from 400nm to 435nm or more preferably 410nm to 430nm
Peak wavelength) can especially influence microorganism growth.Influence to microorganism growth is likely to be dependent on wave-length coverage and dosage.
In certain embodiments, the light of transmitting can include the nearly UV light with peak wavelength in the range of from 410nm to 430nm with
Bacteriostasis is provided (for example, having<9mW/cm2Radiation flux pulsed light), it is (such as logical with radiation to provide bactericidal effect
Amount is in 9mW/cm2To 17mW/cm2In the range of substantially stable state light) or provide anti-microbial effect (for example,
With radiation flux more than 17mW/cm2In the range of, such as in 18mW/cm2To 60mW/cm2In the range of).In certain realities
It applies in example, the transmitting light of near-UV range (for example, 400nm to 420nm or 410nm to 420nm) can also influence microorganism growth
(either in scope of restraining fungi, bactericidal range or antimicrobial range) for such as wound healing, reduces acne blemish
Or treatment atopic dermatitis.
In certain embodiments, at least one luminaire (or multiple luminaires) can be configured as generation in wavelength
Nitric oxide is can trigger in terms of range and flux to store (for example, nitrosoglutathione, nitrosoalbumin, blood from endogenous
At least one of Lactoferrin, nitrosothiols, nitrosamine and metal nitrosyl complexes) release light.In certain implementations
In example, have in 400nm to 435nm or 410nm to 430nm or 430nm to 490nm or 510nm to 550nm or 520nm
The light of peak wavelength in the range of to 540nm can be used for this purpose.
In some embodiments it is possible to using having any one of values below, two, three or more peak value wave
Long light:About 415nm, about 505nm, about 530nm, about 630nm and/or 660nm.
In some embodiments it is possible to any suitable combination of peak wavelength disclosed herein is applied in combination for the phase
(such as vasodilation, inflammation mitigation, enzymatic, nitric oxide generate the therapeutic effect of prestige, nitric oxide releasing and antimicrobial work(
Can).In some embodiments it is possible to during same time window, overlapping but non-coincidence time window during or non-heavy
The combination of wavelength is provided during folded time window.
In some embodiments it is possible to arrange at least one first photophore and at least one second photophore, (it can be with
Implement in the first photophore array and the second photophore array) with a group in combination of the offer selected from following (a) to (f)
The different peak wavelengths closed:(a) the first peak wavelength is in the range of 620nm to 640nm (or 615nm to 635nm), and
Two peak wavelengths are in the range of 650nm to 670nm;(b) the first peak wavelength is in the range of 520nm to 540nm, and second
Peak wavelength is in the range of 650nm to 670nm;(c) the first peak wavelength is at 400nm to 420nm (or 410nm to 430nm)
In the range of, and the second peak wavelength is in the range of 620nm to 640nm;(d) the first peak wavelength 400nm to 420nm (or
410nm to 430nm) in the range of, and the second peak wavelength is in the range of 650nm to 670nm;(e) the first peak wavelength is in 400nm
To 420nm (or 410nm to 430nm), and the second peak wavelength is in the range of 495nm to 515nm;(f)
One peak wavelength is in the range of 400nm to 420nm (or 410nm to 430nm), and the second peak wavelength is in 520nm to 540nm
In the range of.
In certain embodiments, the first luminaire array, which provides, has the first peak wavelength value and the first full width at half maximum value
Spectrum output, wherein the first peak wavelength value subtract the first full width at half maximum value half be more than 400nm.In addition, second shines
Equipment array provides the spectrum output with the second peak wavelength value and the second full width at half maximum value, wherein the second peak wavelength value subtracts
The half of the second full width at half maximum value is gone to be more than 450nm.
In certain embodiments, when being energized to shine, one or more luminaires can provide every square centimeter
At least erg-ten, the energy density of at least 3 joules every square centimeter or at least 5 joules every square centimeter.In certain embodiments,
One or more luminaires can provide 5mW/cm2To 60mW/cm2In the range of radiation flux.
In certain embodiments, one or more luminaires can be arranged to provide basicly stable state
Light.In certain embodiments, one or more luminaires, which can be arranged to, provides multiple discrete light pulses.
In certain embodiments, it can include that there are multiple interconnection panels for delivering the equipment of luminous energy to the scalp of patient
And the FPCB in multiple bending regions limited between multiple panels in multiple panels, FPCB to be allowed to provide concave shape
To cover at least part of patient's calvarium.In certain embodiments, opening is provided between the part of adjacent panels to allow
The conveying of heat and fluid (such as sweat).In certain embodiments, fabric cover may be disposed to covering FPCB, fabric covering
Object is preferably breathable to allow the conveying of heat and fluid conveying (for example, evaporating sweat).In certain embodiments, fabric
Covering can include adjustable closure, be arranged to that the aperture perimeter of fabric cover is allowed to be adjusted.If FPCB
It is comprised in fabric cover, then the adjustment of closure can selectively compress a part of FPCB, and therefore also allow
The aperture perimeter of FPCB is adjusted.In certain embodiments, FPCB and fabric cover be arranged to adaptation expand outwardly and to
Contract with allow the stent of FPCB contact patient scalp.
In certain embodiments, the flexible forming component with generally concave inside, which can be arranged to, receives FPCB.
In some embodiments, flexible forming component can be provided between FPCB and fabric cover.In certain embodiments, FPCB and
Formed parts can be arranged to the scalp for adapting to expand outwardly and allowing multiple stent contact patients to contract.
In certain embodiments, flexible forming component includes central frame and is attached to multiple ribs of frame.It is the multiple
Rib can include at least one preceding rib, at least one aft rib and at least two cross ribs, wherein, each rib in the multiple rib
It is substantially protruded outward from central frame, to limit the outside of generally concave inside.In certain embodiments, fabric cover can
To include multiple bags (pockets), the multiple bagging is set to the multiple ribs of reception and is completely covered so that fabric cover is maintained at
The position of flexible forming component and FPCB.In certain embodiments, fabric cover includes being arranged to the head for being worn on patient
The outmost surface of wearable cap in portion.
In certain embodiments, other than multiple ribs, flexible forming component can include the panel of multiple bendings, described
The panel of multiple bendings generally outwards and is downwardly projected the part to substantially conform to calvarium from central frame, wherein, it is multiple curved
The panel being each bent in bent panel is arranged between two different ribs in multiple ribs.In certain embodiments, may be used
To provide gap between the part of adjacent rib and the panel of bending to adapt to expand outwardly and to contract, and can dissipate
The heat generated by least one luminaire associated with the FPCB being maintained in flexible forming component.In some embodiments
In, flexible forming component can be made of suitable polymer material.
In certain embodiments, the central frame of flexible forming component include be configured to receive electric-device housing hole or
Opening.In certain embodiments, electric-device housing can include drive circuit (or at least part of drive circuit),
It is configured as encouraging at least one luminaire so that illumination is mapped on the scalp of patient.In certain embodiments, electronics device
Part shell can include one or more user interfaces, Sensing interface, charging interface, data-interface, signal input part, signal
Output terminal and/or display element.In certain embodiments, energy storage device (for example, battery) can be by pivotally (or with it
His mode is movably) battery holder that is coupled to electric-device housing keeps.It is such removably coupled to allow
Relative movement between battery holder and electric-device housing, phototherapy apparatus to be allowed to adapt to that there is different head sizes and shape
The various patients of shape.
In certain embodiments, the operation of equipment as disclosed herein can in response to by one or more sensors or
One or more signals that other elements generate.It is expected that various types of sensors, including temperature sensor, photoelectric sensing
Device, imaging sensor, proximity sensor, pressure sensor, chemical sensor, biosensor, accelerometer, humidity sensor
Device, oximeter, current sensor, voltage sensor etc..The operation of the irradiation and/or equipment disclosed herein that may influence light
Other elements include timer, cycle rate counter, the control element of manual operation, radio transmitter and/or receiver (can be with
Implement in a transceiver), laptop or tablet computer, mobile phone or other portable digital devices.It can be herein
Wired and or wireless communications are provided between disclosed equipment and the generation of one or more signals or signal receiving element.
In certain embodiments, luminaire as disclosed herein may be configured to prevent controlling beyond authorized quantity
The unauthorized for treating the period uses.In certain embodiments, the quantity of the treatment cycle of equipment can be increased and be stored in counting
In device or other memory components.In certain embodiments, when the quantity for the treatment of cycle reaches scheduled limitation, the behaviour of equipment
Work reversibly or can be disabled irreversibly.It in certain embodiments, can when the quantity for the treatment of cycle reaches preset limit
User is notified to reach the preset limit of the quantity for the treatment of cycle, and user can be carried to transmit a signal to user
Show:I) new equipment or its component are bought or (ii) purchase is continuing with equipment up to the additional period of specified quantity or refers to
The ability of fixed extra time section.In certain embodiments, it is related that use outside purchase volume is used and/or allowed users to the period
One or more signals can be transmitted via wired or wireless way.In certain embodiments, user can be following
The application used on personal computer, tablet computer, mobile phone or another portable digital device is loaded in, and the application can
To provide period use information and/or the period outside user's purchase volume or the usage time outside purchase volume allowed to be continuing with setting
It is standby.
In certain embodiments, in the access times specified for detecting equipment, luminaire can be configured as life
Into the disabling signal for being adapted to irreversibly disablement device, to prevent the further operating of equipment.In certain embodiments, prohibit
It can be included being arranged at least one of due to voltage spikes and current spike for damaging at least one circuit element with signal.
In some embodiments, luminaire include power circuit, the power circuit be arranged to provide for equipment microcontroller and/or
At least one power signal after the adjustment that at least one luminaire uses, and disable signal and can be adapted to irreversibly
Disable at least one element of power circuit.In certain embodiments, the connection of at least one fuse can be arranged to at least
One luminaire is electrically connected, and disables signal and can be adapted to disconnect at least one fuse connection to prevent electric current from being supplied
At least one luminaire should be arrived.In certain embodiments, at least one fuse connection can be arranged to and at least one hair
Light device and/or photophore drive circuit are electrically connected.
In certain embodiments, the irradiation of the light in living tissue and/or operation equipment as disclosed herein can be rung
It should be in one or more temperature signals.It for example, can be on FPCB or its proximity sensing temperature regime;Instruction temperature can be generated
At least one signal of degree situation;And it can control to deliver to the scalp of patient in response at least one signal
The operation of the equipment of luminous energy.Such control can include the startup of the operation of light-emitting component, operation deviation (or change) or
The termination of person's operation.In some embodiments it is possible to threshold temperature (such as>42 ° Celsius) under heat be provided turn back protection, to prevent
Only user is subjected to burning or uncomfortable.In certain embodiments, heat protection of turning back may be in response to receive instruction excess temperature situation
Signal and trigger luminaire carry out termination operation, reduce electric current or change mode of operation.
In certain embodiments, proximity sensor can be disposed proximate to a part of FPCB, when to determine FPCB
Close to surface to be illuminated (for example, scalp) and for by when keeping off in the surface reduce flux come realize for
The safety of patient.
In certain embodiments, can include being arranged to generate visual letter for delivering the equipment of luminous energy to the scalp of patient
Number the appreciable optical signal element of user (for example, one or more lamps, light-emitting diode display, aplhanumeric visual display, shifting
Dynamic application program etc.) and/or be arranged to generate earcon the appreciable earcon element of user (such as loud speaker,
Buzzer, alarm generator etc.).In certain embodiments, at least one of optical signal and earcon indicating equipment
Mode of operation or charged state.In certain embodiments, the behaviour of at least one of optical signal and earcon indicating equipment
Make the counting in period.
In certain embodiments, the equipment for being used for the scalp delivering luminous energy to patient as disclosed herein can include using
The memory component of the information of one or more sensor signals is indicated in storage.Such information can be used for detection device
Using, assessment patient's states, assessment patient improve and assessment equipment function.In certain embodiments, one or more is indicated
The information of multiple sensor signals can be via wired or wireless device (for example, suitable via bluetooth, WiFi, Zigbee or another
The agreement of conjunction) it is transferred to mobile phone, computer, data recording equipment or local area network, wide area network can be alternatively coupled to
Another suitable equipment of network, telephone network or other communication networks.In some embodiments it is possible to provide data port (example
Such as, micro USB or other types) to allow to extract or inquire the information included in memory.
The following describe for luminous energy to be delivered to the details of the illustrative device of the scalp of patient.
Fig. 1 is to implement the decomposition of the luminaire 5 in the wearable cap for luminous energy to be delivered to the scalp of patient to regard
Figure.Equipment 5 is included by the FPCB10 multiple photophores supported and stent, and FPCB10 includes multiple interconnection of arrangement concavity configuration
Panel 12A-12F (for example, multiple interconnection elements).Spill formed parts 30 (include the face of frame 31, rib 32A-32D and bending
Plate 34A-34D) it is configured as receiving FPCB10.Fabric cover 60 is configured to covering spill formed parts 30 and is included in
FPCB10.Battery 50 and battery holder 51 are configured between FPCB10 and spill formed parts 30.Electric-device housing
40 are arranged to be contained in opening 31A, and opening 31A is limited in the frame 31 of spill formed parts 30.It is pivotally connected element
41A, 51A (for example, cylindrical tab) are arranged to battery holder 51 being pivotally coupled to electric-device housing 40.Electronics
Device board 41 can be inserted into electric-device housing 40, and electric-device housing 40 is covered by 42 closings.In electronic panels 41
It is disposed with cycle rate counter 43, control button 44, charging/data port 45 and status lamp 46.With electric-device housing 40 and electricity
The sub- associated various elements of device board 41 may be generally referred to as " control module ".Window 42A defined in covering 42 is carried
For the access to cycle rate counter 43, control button 44, charging/data port 45 and status lamp 46.Fabric cover 60 includes
Fabric body 61 and the multiple inner bag 62A-62D for being arranged to receive a part of rib 32A-32D.At the top of fabric cover 60
Opening 68 be arranged to receive covering 42.
The other of spill formed parts 30, electric-device housing 40 and battery holder 51 is provided in Fig. 2A -2F
View.Fig. 2A is perspective upper view, and Fig. 2 B are top plan views, and Fig. 2 C are front views, and Fig. 2 D are left side views, under Fig. 2 E are
Portion's perspective view and Fig. 2 F are bottom plan views.As shown in Figure 2 A, rib 32A-32D and the panel 34A-34D of bending are from frame
31 generally outwards and are downwardly projected.The panel 34A-34D of bending does not preferably extend downwardly to rib 32A-32D.It is provided in Fig. 2 B
Top plan view shows that when viewed from above, spill formed parts 30 have roughly elliptical shape.In some embodiments
In, rib 32A-32D, the panel 34A-34D of bending and frame 31 can by suitable method (such as molding) and by one or
More material pieces are made.As shown in Fig. 2 B-2D, gap 33A1 to 33D2 be arranged on adjacent rib 32A-32D part and
Between the panel 34A-34D of bending, to adapt to expand outwardly and to contract, and can transmit heat and/or fluid (such as
The sweat of evaporation).Covering 42 can be flushed substantially with the top edge of central frame 31 or almost be flushed.Such as Fig. 2 C and 2D
Shown, preceding rib 32A can be shorter than cross rib 32B, 32D and aft rib 32C.
As illustrated in figures 2 e and 2f, electric-device housing 40 can be received including interstitial hole 40A, 40B with accommodating
The fastener (not shown) of FPCB10.Electric-device housing 40 further includes corner apertures 40C, and corner apertures 40C, which is arranged to receive, to be used to incite somebody to action
Covering 42 is attached to the additional fasteners (not shown) of electric-device housing 40.It is shown in Fig. 2 E by pivoting coupling member
Pivots of the part 51A between battery holder 51 and electric-device housing 40 couples.As illustrated in figures 2 e and 2f, battery holder 51
The lower section of panel 34B, 34C being bent after aft rib 32C and two are located substantially at, battery 50 has thin low profile shape.One
In a embodiment, battery 50 preferably provides at least 3.7V and at least flexible battery of 1000mAh.
Show that FPCB10 or part thereof is in the various views of flat configuration in Fig. 3 A-3D.
Fig. 3 A are the bottom plan views with the photophore 20 being disposed thereon and the FPCB10 of stent 25.FPCB10 packets
Include polyimide substrate 11, inner surface 11A and outer surface 11B (as shown in Fig. 1,3E, 3G and 3H).Preferably, FPCB10 along
Front and back is encapsulated with suitable translucent material (such as PETG or silicone (not shown)).In one embodiment, photophore 20
Including 280 light emitting diodes in total, the light emitting diode be arranged to 56 series connection 5 LED, string voltage be 11V, electric current
It is 3.08 watts to be limited to 5mA and power consumption.Fig. 3 A show 36 stents 25 from the inner surface 11A extensions of FPCB10.
FPCB10 includes the panel 12A-12F of six interconnection, and panel 12A-12F is connected to each other by the tab area 13B-13F to narrow.
Gap 14A-14F is arranged between each panel 12A-12F, and (it is close to the tab area to narrow by these gaps 14A-14F
13B-13F extends) available for allowing the conveying (such as evaporation of sweat) of heat and/or fluid between panel 12A-12F.Such as
Shown in Fig. 3 A, hole 15A, 15B be defined through FPCB10 with receive for by FPCB10 engagements to being limited to electric-device housing
The fastener (not shown) of corresponding hole 40A, 40B in 40.In addition opening 15C can be provided for being configured to spill
It communicates during construction in sensor of the proximity sensor (for example, photoelectric sensor) between the inside of FPCB10.
Fig. 3 B are the bottom plan views of the substrate 11 of FPCB10, show before photophore is installed and are forming branch
The electric trace 17 and transmitter installing zone arranged before frame and on the substrate 11 before substrate 11 is configured to concave configuration
Domain 18.As shown in Figure 3B, each transmitter installation region 18 includes two anodes and two cathodes, enables to installation and includes
More LED soild state transmitters packaging of the LED of different peak wavelengths.At each transmitter installation region 18 there are multiple anodes and
Cathode allows the LED of different peak wavelengths differently to be controlled.Fig. 3 C are from bottom (for example, as substrate 11 is transparent)
The viewgraph of cross-section of the FPCB10 arrived shows the electric trace 16 along the top side of substrate 11.
Fig. 3 D are the bottom plan views of FPCB10 profiles, show that substrate 11 is configured to concave shape to be bonded
Bending region and bending angle around the scalp of user.As shown in Figure 3D, buckled zone is provided between each panel 12A-12F
Domain, and each panel 12A-12F includes additional bending region.First panel 12A include two longitudinal bend areas and
Angular distortion region.Second panel 12B includes five bending regions.Third panel 12C and fourth face plate 12D includes a bending
Region.5th panel 12E and the 6th panel 12F includes four bending regions.
Fig. 3 E to 3H provide the various views of the FPCB10 of concave configuration, including perspective upper view (Fig. 3 E), lower flat
View (Fig. 3 F), left side view (Fig. 3 G) and top front perspective view (Fig. 3 H).Fig. 3 E, 3G and 3H show forming FPCB10
Outer surface 11B, and Fig. 3 F show inner surface 11A.As the concave shape shown in from Fig. 3 E-3H will become apparent from, the first face
Plate 12A is configured to the calvarium of covering user, and second panel 12B is configured to a part for covering user's forehead, third panel and the
Four panel 12C, 12D are configured to the eyelid of covering user, and the 5th panel and the 6th panel 12E, 12F are arranged over using account
The rear portion in portion.
Fig. 4 A-4D provide the various views of the equipment 5 of the assembling of Fig. 1, including perspective upper view (Fig. 4 A), top planes
View (Fig. 4 B), front view (Fig. 4 C) and left side view (Fig. 4 D).Most of outer surface of equipment 5 includes fabric cover
60, the covering 42 for electric-device housing 40 is implemented in uppermost outer surface.Fabric cover 60 includes fabric body 61
With multiple (inside) the bag 62A-62D for being arranged to the part for receiving rib 32A-32D.
Fig. 5 A are the front views for the luminaire for being superimposed upon assembling above simulation human head, in Fig. 4 A-4D.Such as figure
Shown in 5A, equipment 5 is implemented in the cap above ear of its lower edge between the forehead and hair line of user and in user
In.Fig. 5 B are the side views of a part for the luminaire of Fig. 1,4A-4D and 5A, and spill formed parts and fabric covering are omitted
Object is to show FPCB10, electronics housing 40, covering 42, battery holder 51 and battery 50 relative to the head of user
Plan is placed.As shown in Figure 5 B, at least part of the calvarium of FPCB10 and patient closely conforms to.
Fig. 6 is the schematic diagram for the fabric covering member 60A for including adjustable closure member, which is included by cloth
It is set to part 68A, 68B of the aperture perimeter for allowing to adjust fabric covering member 60A.In certain embodiments, it can adjust and be closed
Part can include hook and loop straps, snap closure, the alternative compression fitting operated or the fabric ends that can be tied in a knot.
Fig. 7 A-7F illustrate the viewgraph of cross-section of the part of flexible light emitting device, respectively include from the multiple luminous members of support
The stent of the FPCB extensions of the encapsulation of part, wherein stent have different shape and volume in each case.
Fig. 7 A are to include the branch with the circular structure being bent upwards from the FPCB10 extensions for supporting multiple photophores 20
The side viewgraph of cross-section of a part for the first luminaire of frame 25A.The transmitting of multiple photophores 20 weight above stent 25A
It is folded.The inner surface 11A and outer surface 11B of FPCB10 is covered by sealant material 19A, 19B.The volume of stent 25A is 22.42
Cubic millimeter.
Fig. 7 B are the side sectional views of a part for the second luminaire, which includes having more from supporting
The stent 25B of the round column structure of the FPCB10 extensions of a photophore 20.The transmitting of multiple photophores 20 weight above stent 25B
It is folded.The inner surface 11A and outer surface 11B of FPCB10 is covered by sealant material 19A, 19B.The volume of stent 25B is 34.89
Cubic millimeter.
Fig. 7 C are the side sectional views of a part for third luminaire, which includes having more from supporting
The stent 25C of the taper column structure of the FPCB10 extensions of a photophore 20.The transmitting of multiple photophores 20 weight above stent 25C
It is folded.The inner surface 11A and outer surface 11B of FPCB10 is covered by sealant material 19A, 19B.Stent 25C has 35.5 cubes
The volume of millimeter.
Fig. 7 D are the side sectional views of a part for the 4th luminaire, and the 4th luminaire includes having more from supporting
The stent 25D of the concave conical configuration of the FPCB10 extensions of a photophore 20.The transmitting of multiple photophores 20 weight above stent 25D
It is folded.The inner surface 11A and outer surface 11B of FPCB10 is covered by sealant material 19A, 19B.Stent 25D has 62.89 cubes
The volume of millimeter.
Fig. 7 E are the side sectional views of a part for the 5th luminaire, and the 5th luminaire includes having more from supporting
The stent 25E of the flat addendum cone construction of the FPCB10 extensions of a photophore 20.The transmitting of multiple photophores 20 is above stent 25E
Overlapping.The inner surface 11A and outer surface 11B of FPCB10 is covered by sealant material 19A, 19B.The volume of stent 25E is
77.31 cubic millimeters.
Fig. 7 F are the side sectional views of a part for the 6th luminaire, and the 6th luminaire includes having more from supporting
The stent 25F of the circular structure of the FPCB10 extensions of a photophore 20.The transmitting of multiple photophores 20 weight above stent 25F
It is folded.The inner surface 11A and outer surface 11B of FPCB10 is covered by sealant material 19A, 19B.The volume of stent 25F is 92.82
Cubic millimeter.
As shown in Fig. 7 A-7F, according to such as users'comfort, material volume and light interaction and/or photoresist characteristic
Consider, various stent shape and size can be used.
Fig. 8 is to show to be used between the component of the luminaire of the scalp delivering luminous energy of patient according to one embodiment
Interconnection schematic diagram.Microcontroller 102 is arranged to be received via 5V booster circuits 112 from battery 122 (nominally 3.7V)
Electric power.Microcontroller 102 can be arranged to the charging that control is arranged between Minimized USB connector 116 and battery 122 and integrate
Circuit 114, wherein Minimized USB connector 116 can be used to receive electric current to charge to battery 122.In certain implementations
In example, Minimized USB connector 116 can be also used for being to and from microcontroller 102 and/or associated memory transmission data
And/or instruction.Microcontroller 102 is also arranged to control 12V booster circuits 118 to increase one or more LED arrays 120
Voltage.Microcontroller 102, which also controls, to be arranged to one or more LED for driving one or more LED arrays 120 and drives
Dynamic device circuit 110.Microcontroller 102 is also arranged in receiving from user's load button 104, temperature sensor 124 and close biography
The input of sensor 126 (it includes infrared LED 128).Microcontroller 102 is also arranged in output signal being supplied to LCD display
106 and buzzer 108.Certain components are located at relative to controller FPCB outside plate, as shown in the vertical dotted line in Fig. 8.It is shining
In the operation of equipment, user can press button 104 to start to operate.If proximity sensor 126 detect equipment by
It is placed on the head of user, then microcontroller 102 can trigger one or more LED driver circuits 110 to encourage one
A or more LED array 120.With temperature sensor 124 come the temperature during monitoring operation.If detecting overheating conditions,
Then microcontroller 102 can take appropriate action and be supplied to one by one or more LED driver circuits 110 to reduce
Or more LED array 120 electric current.Operation can continue, until timer (for example, inside microcontroller 102) makes operation
It is automatic to terminate.One or more indicator LED (not shown) can provide the visual letter of the charged state of instruction battery 122
Number.Earcon for starting and terminating operation can be provided by buzzer 108 or suitable loud speaker.It is related to use week
The information of phase, usage time or any other suitable parameters can be shown by LCD display 106.
Fig. 9 be describe according to one embodiment be suitable for operation for luminous energy is delivered to patient scalp luminaire
Hardware driver, interface between functional unit and software application schematic diagram.Application including timer and counter 107
Performing function 103 can be performed using one or more integrated circuits (microcontroller 102 such as shown in Fig. 8).Hardware
Driver 105 can be used for outputting and inputting element interface with various, for example, one or more LED arrays 120, loud speaker
Or buzzer 108, LCD display 106, temperature sensor 124, user's load button 104 (for example, button push), indicator
LED109 and optical sensor 126.
The phototherapy of scalp that Figure 10 A-10E illustrate according to another embodiment for luminous energy to be delivered to patient is set
It is standby.More specifically, Figure 10 A are the perspective upper views of phototherapy apparatus, Figure 10 B are lower perspective views, and Figure 10 C are right side views, figure
10D is bottom plan view, and Figure 10 E are decomposition views.As discussed in more detail below, phototherapy apparatus 210 can include
Flexible cap 212, flexible printed circuit board (FPCB) component 214, flexible biconvex lens 216, multiple stent 218a, 218b, foam
Filler 220a, 220b and jointing edge 221 (as illustrated in figures 13 a and 13b).
Flexible cap 212 can include one or more of different fabrics or material (for example, cotton, trepanning or the poly- second of closed pore
Alkene foam, polyester, artificial silk etc.), and can be formed according to the head sizes of patient with a variety of different shape and size.
In some embodiments, flexible cap 212 includes Stretch material to adapt to various head sizes.Flexible cap 212 includes proximal face
222 (for example, can differently be described as bottom surface, lower surface, inner surface, interior surface or the surface close to patient) and distal side table
Face 224 is (for example, it can differently be described as top surface, upper surface, outer surface, outer surface or the table from patient farther out
Face).Flexible cap 212 forms general size and shape is designed to receive the recess portion 226 of the upper part of patients head, and can
To include being configured as rear extension 228 (e.g., nape, rear hair line, the occipital bone protrusion of the lower rear portion of covering patients head
And/or near it etc.).Close to rear extension 228 (but being directed towards the center of flexible cap 212), flexible cap 212 can include bending
Arc (for example, left arc of curvature 229a and right arc of curvature 229b), extension 228 is easier to be bent outwardly to adapt to difference after allowing
Head sizes.
In certain embodiments, flexible cap 212 can include sealing-plug 232, which is removably attached to simultaneously
Cover the electronics connectivity port 230 at the top of flexible cap 212.Electronics connectivity port 230 is attached mechanically to be arranged in flexibility
Electronic receptacle 234 at the top of cap 212.Sealing-plug 232 covers and protects electronics connectivity port 230 from damage when not in use
It is bad.Electronic receptacle 234 may be configured to receive FPCB components 214 and (be shown in Figure 11 A and 11B and in further detail below
Ground discussion) electronic sub-component 250, with to electronic sub-component 250 provide mechanical stability.For example, electronic receptacle 234 can be with machine
It is attached to tool and fixed to electronic sub-component 250, to prevent the relative movement between them.Electronics connectivity port 230 (has electricity
Sub-socket 234) electronic sub-component 250 can be provided with the electronic equipment outside phototherapy apparatus 210 (for example, computer, intelligence electricity
Words etc.) or electric power connector (for example, power cord, USB line etc.) between machinery and/or electronics connection, with receive electric power and/or
Electronic data (for example, operating parameter).In some embodiments it is possible to provide nothing between phototherapy apparatus 210 and electronic equipment
Line communicates.In certain embodiments, the battery for being operatively coupled to FPCB components 214 can be by induction charging (for example, wireless charging
Electricity).
Including proximal face 236, (it can differently be referred to as bottom table to FPCB components 214 (being discussed more fully below)
Face, lower surface, inner surface, interior surface or the surface close to patient) and distal surface 237 (it can differently be referred to as pushing up
Surface, upper surface, outer surface, outer surface or the surface far from patient).FPCB components 214 form general size and shape quilt
The recess portion 238 of at least upper part of patients head is configured to receive, and rear extension 239, the rear extension can be included
239 be configured to covering patients head lower part rear portion (for example, nape, rear hair line, occipital bone protrusion and/or its near
Deng).Proximal face 236 includes at least one luminaire (for example, LED), and can include being configured as generating have one
Multiple LED devices of the transmitting (for example, red LED and/or blue led) of a or more peak wavelength are such as begged in detail above
Opinion.
Flexible biconvex lens 216 include proximal face 252 (such as inner surface, interior surface, surface close to patient) and
Distal surface 254 (for example, outer surface, outer surface, surface far from patient).Flexible biconvex lens 216 forms general size
Be designed to the recess portion 256 on head for being suitble to patient with shape, and may include rear extension 258, the rear extension 258 by with
Be set to covering patient head back low portion (for example, nape, rear hair line, occipital bone protrusion and/or its nearby etc.).It connects
Extension 258 (but being directed towards the center of flexible biconvex lens 216) after near, flexible biconvex lens 216 can include arc of curvature
259a, 259b, extension 258 is easier to be bent outwardly to adapt to different head sizes after allowing.Flexible biconvex lens 216
It can be molded, can have the thickness of about 0.02 inch to 0.06 inch (such as about 0.033 inch), and can have
There are about 20 to about 60 lens of about 10 to about 80 lens of per inch or per inch or per inch about 30 to about
The lens density of about 40 lens (LPI) of 50 lens or per inch, but other sizes can also be used.According to the material used,
If the thickness of flexible biconvex lens 216 is less than about 0.02 inch, undesirable corrugation or curling may be caused, and if
The thickness of flexible biconvex lens 216 is more than 0.02 inch, then may be not flexible enough or stretchable to adapt to the head of different patients
Size.
In certain embodiments, flexible biconvex lens 216 can include filling out along the peripheral edge of flexible biconvex lens 216
Recess 260 is filled, to receive foam insert 220a, 220b (so that foam fills out the flexible biconvex lens nearside of object 220a, 220b contact
Surface 252).In this way, filling recess 260 and foam insert 220a, 220b can be in size and/or shapes each other
It is substantially complementary.In certain embodiments, filling recess 260 and foam insert 220a, 220b can be configured as along flexibility
Entire periphery edge or the part of it extension of biconvex lens 216.Foam insert 220a, 220b provide additional comfort liner and
Compressible stratum, to improve the stickiness with the head of patient.In certain embodiments, foam insert 220a, 220b can
It is attached to flexible biconvex lens proximal face 252 (such as by Velcro (Velcro)) with removing so that foam-filled
Object 220a, 220b can be washable and/or replaceable.
FPCB components 214 are located between flexible cap 212 and flexible biconvex lens 216.More specifically, FPCB components
214 are positioned in flexible cap recess portion 226 so that FPCB components distal surface 237 is close to flexible cap proximal face 222.It is flexible
Biconvex lens 216 is positioned in FPCB components recess portion 238 so that flexible biconvex lens distal surface 254 is positioned proximate to
FPCB components proximal face 236.In this way, when flexible cap 212, FPCB components 214 and flexible biconvex lens 216 are assembled
When together, recess portion and peripheral edge are usually in alignment with each other.In an identical manner, flexible cap recess portion 226, FPCB recess portions 238
It is all substantially in alignment with each other with flexible biconvex lens recess portion 256;Extension 239 and soft after extension 228, FPCB components after flexible cap
Extension 258 is all substantially in alignment with each other after property biconvex lens;And flexible cap arc of curvature 229a, 229b and flexible biconvex lens are curved
Bent arc 259 is usually in alignment with each other.It can be along the peripheral edge of flexible cap 212, FPCB components 214 and flexible biconvex lens 216
Positioning combination edge pressed from both sides for 221 (as shown in Figure 13 B) so that they to be fixed together (for example, the inwardly biasing of jointing edge folder 221).
Multiple stent 218a, 218b can include being located at the top of flexible biconvex lens 216 or along flexible double
The top-support 218a of the top positioning of convex lens 216 and it is positioned in the side of flexible biconvex lens 216 or along flexibility
The side stand 218b of the side of biconvex lens 216.Each stent 218a, 218b include proximal end 262 and distal end 264.Stent 218a,
218b is positioned between flexible biconvex lens 216 and FPCB components 214.In certain embodiments, stent 218a, 218b can be with
To flexible biconvex lens 216 or (example can be integrally formed with flexible biconvex lens 216 in attachment (such as passing through adhesive)
Such as, by with flexible biconvex lens 216 molded support 218a, 218b simultaneously).More specifically, for each stent 218a,
218b, mount proximal end 262 contacts flexible biconvex lens distal surface 254 (and therefrom stretching out), and rack far end 264 can connect
Touch FPCB components proximal face 236 so that between FPCB components proximal face 236 and flexible biconvex lens distal surface 254
Distance is not less than the height of stent 218a, 218b.The height of stent 218a, 218b can be more than the height of LED (in multiple LED)
Degree, to prevent flexible biconvex lens distal surface 254 from contacting LED (and/or any one of multiple LED).Stent 218a,
218b keeps the minimum range between flexible biconvex lens distal surface 254 and FPCB components proximal face 236, such as following more detailed
Carefully discuss.
Figure 11 A-11C are the views of FPCB components 214.More specifically, Figure 11 A are the rearviews of FPCB components 214, figure
11B is side sectional view, and Figure 11 C are decomposition views.FPCB components 214 include panel sub-component 240 (for example, multiple interconnection
FPCB panels or element) and electronic sub-component 250.Electronic sub-component 250 is attached to panel sub-component 240 by installed part 266,
Installed part 266 also accommodates electronic circuit wherein.Installed part 266 includes the multiple attachmentes extended from its bottom surface, wherein more
A attachment includes lug 268a, 268b, engagement pin 270, screw pole 272, pin receptacle 274 etc..Installed part 266, which further includes, to be prolonged
Extend through electric ports 275 therein.In certain embodiments, electric ports 275 may be embodied as in external electronic device or
The electric power connector both mechanically and electrically to communicate is provided between connector and electronic sub-component 250 (explaining in further detail below).
The bottom surface that electronic sub-component 250 is additionally included in installed part 266 surrounds the O-ring that electric ports 275 position
276.Electronic sub-component 250 further includes control printed circuit board (PCB) 278, include being used for control panel sub-component 240 (with
And the LED being mounted thereto) operation drive circuit.PCB278 is controlled to include multiple attachmentes, including screw hole 280 and fork
Hole 282.Screw hole 280 accommodates the screw 284 passed through, extends in mounting screw column 272, so as to control PCB278
It is attached to the bottom surface (although any other suitable fastener or attached device can be used) of installed part 266.Lug 268b
And/or spine 269 corresponding thereto will further be controlled by preventing control PCB278 relative to the transverse shifting of installed part 266
PCB278 processed is fixed to installed part 266 (lug 268b can also be inserted into the groove in panel sub-component 240 or hole).
The connector circuit of electric ports 275 and control PCB278 and the (institute in Figure 10 E of flexible cap socket for electronic part 234
Show) alignment, it is linked into external electronic device (for example, computer, smart phone etc.) to provide PCB electronic device connectors or connects
Enter to electric power connector (for example, power cord, USB line etc.) to receive electric power and/or electronic communication (for example, instruction, software are more
Newly, operating parameter, operation data etc.).
Electronic sub-component 250 further comprises being attached by battery package 288 (for example, binder film, mechanical organ etc.)
To the battery 286 of the bottom surface of installed part 266.FPCB locking pads 290 are located in FPCB components proximal face 236 and and FPCB
Snap lock 292 is aligned.FPCB snap locks 292 include extending through the slit 304 of panel sub-component 240, across control PCB entries
282 and across installation pin receptacle 274 engagement pin 294 (such as outwardly biased), so as to by panel sub-component 240, control
PCB278 and installed part 266 processed are fixed to one another.Therefore, PCB278 and battery 286 is controlled to be oriented adjacent to each other, and the two
All contact (or being positioned proximal to) FPCB components distal surfaces 237.
Figure 12 A-12E show panel sub-component (also being shown in Figure 11 A-11C).More specifically, Figure 12 A are bending structures
The bottom perspective view of panel sub-component made, Figure 12 B are the bottom plan views of the panel sub-component of curved configuration, and Figure 12 C are
The side cross-sectional view of panel sub-component, Figure 12 D are the panel of construction for having the flat of shown bending region and being fully deployed
The top plan view of component, and Figure 12 E are the bottom plan views of the panel sub-component of construction that is flat and being fully deployed.
Panel sub-component 240 includes the FPCB panels of multiple interconnection, can be bent and move relative to each other (for example,
The region that reduces along width uses hinge shape structure) to form different dihedral angles.Panel sub-component 240 includes having quilt
It is positioned at the main body 300 (for example, one or more main body panels) of the reinforcer part 302 between two straight slots 304.As above
Described, straight slot 304 receives FPC snap locks engagement pin 294 (show and be discussed above in Figure 11 A-11C) and and electronics
Sub-component control PCB entries 282 and electronic sub-component installation pin receptacle 274 are aligned.
Main body 300 includes the multiple radially extending portion (examples generally circumferentially positioned around the peripheral edge of main body 300
Such as, a series of panel of interconnections).More specifically, main body 300 includes forward extension 306, rear extension 324 (with preceding extension
Portion 306 relatively extends), left extension 328a (between forward extension 306 and rear extension 324 and left side), right extension
Portion 328b (being located between 306 and rear extension 324 and right side of forward extension point), left front extension portion 332a (prolong before being located at
Extending portion is point between 306 and left extension 328a), left rear extension portion 338a (be located at rear extension 324 and left extension 328a
Between), behind right forward extension 332b (between forward extension 306 and right extension 328b) and the right side extension 338b (positions
Between rear extension 324 and right extension 328b).Each extension can include separately curved to allow by being bent region
One or more panels of other relative movements (for example, forming the dihedral angle of variation) that are bent or allowing therebetween.
Forward extension 306 is attached to main body 300 in proximal end, and its distal end (opposite with proximal end) includes reinforcer part
308 and the active pad 322 of capacitance touch.Reinforcer part 308 is arranged at distal surface 237 (for example, top surface), and
The active pad 322 of capacitance touch is arranged at proximal face 236 (for example, bottom surface), reinforcer part 308 and capacitive touch
It touches with source pad 322 relatively but is in alignment with each other.Forward extension 306 further includes the left side in the left side for the distal end for being attached at forward extension 306
Side flap 312a and be attached at forward extension 306 distal end right side right flank piece 312b.
Capacitance connector (capacitive tab) 316 is attached to the distal end of forward extension 306 by neck 318.Capacitance connects
First 316 are included in the reinforcer part 320 in distal surface 237 and the signal protection part 310 in proximal face 236, wherein
Reinforcer part 320 and signal protection part 310 are arranged to relative to each other but are in alignment with each other.Capacitance connector 316 can pass through neck
Portion 318 is bent outwardly so that capacitance joint reinforcing part part 320 and preceding extension reinforcer part 308 are in contact with each other.Such
In construction, capacitance joint reinforcing part part 320, signal protection part 310, preceding extension reinforcer part 308 and preceding extension condenser type
Active pad 322 is touched to be in alignment with each other.In an alternative embodiment, capacitance connector 316 can be curved inwardly by neck 318.At this
In the configuration of sample, extension reinforcer part 308 and capacitance joint reinforcing part part 320 can be arranged along proximal face, preceding to prolong
Signal protection part can be included, and capacitance connector 316 can include capacitance at distal surface at distal surface by stretching part 306
Formula touches active pad.
Extension 324 is attached to main body 300 in proximal end afterwards, and includes left wing piece 326a and right flank piece in far-end
326b.Left extension 328a is attached to main body 300 in proximal end and includes forward tab 330a in far-end.Right extension
328b is attached to main body 300 in proximal end, and includes forward tab 330b in distal end.Left front extension 332a is attached in proximal end
Main body 300, and include forward tab 334a with after to fin 336a in distal end.Left back extension 338a is attached to master in proximal end
Body 300, and to fin 340a after distally including.Right forward extension 332b is attached to main body 300 in proximal end, and in distal end
Including forward tab 334b and backward fin 336b.Extension 338b is attached to main body 300 in proximal end behind the right side, and is wrapped in distal end
Include backward fin 340b.
Extension and fin can respectively include one or more panels and/or bending region 352a, 352b.More specifically
Say that as indicated in fig. 12d, extension and fin can respectively include one or more horizontal curvature region 352a (for example, horizontal in ground
To in the radius bend of main body 300).At least part of each extension can be by vertical curve region 352b (along master
The radius bend of body 300) it is connected at least part of respective airfoil.Being bent region 352a, 352b allows panel sub-component 240
Meet the shape on the head of patient (for example, vertical curve region 352b makes panel sub-component 240 and the circumference one on the head of patient
It causes).Fin can be attached to its corresponding extension along the entire side of fin or part of it.
Panel sub-component 240 in its proximal face 236 include it is multiple reservation region (keep-outareas) 350a,
350b.When FPCB components 214 and flexible biconvex lens 216 fit together, retain region 350a, 350b usually with multiple
The distal end 264 of frame 218a, 218b are aligned (and being larger than), with the circuit of protection panels sub-component 240, and prevent stent
218a, 218b contact the photophore for being installed to panel assembly 240.More specifically, top retains region 350a and top-support
218a is aligned and contacts, and side retains region 350b and is aligned and contacts with side supports 218b.In certain embodiments, panel
Sub-component 240 can include sealant layer.
Figure 12 F-12H show capacitor.More specifically, Figure 12 F are the cross sections of flexible printed circuit board (FPCB)
View, the flexible printed circuit board combine for before FPCB is folded (in the direction of curved arrow C, along fold line
AA it) manufactures capacitor and bonds the element of capacitor element.Figure 12 F show to be arranged in FPCB306 that (it can be embodied in forepart
In extension board) coating 305A and carrier (for example, polyimides) layer 305B between layers of copper 305C, capacitance touch is active
Pad 322 and signal protection part 310 be further mounted to FPCB306 (preferably above the first surface of carrier layer 305B, and
It is electrically connected with the trace formed by layers of copper 305A).Along extension reinforcer part 308 before the second surface setting of carrier layer 305B
With capacitance joint reinforcing part part 320, respectively close to signal protection part 310 and the active pad 322 of capacitance touch.When along folding
When line A-A folds FPCB in the direction of curved arrow C, adhesive (or double faced adhesive tape) 325 is along one or more reinforcers
Part 308,320 is arranged, to provide nonconducting bonding therebetween.Figure 12 G are folded and reinforcer part in FPCB306
The capacitor 353 manufactured after bonding between (or spacer element) 308,320 by the FPCB306 shown in Figure 12 F and element
Viewgraph of cross-section.In certain embodiments, the front of fold line A-A extension FPCB306 it is a part of can implement with
The continuous capacitance connector 316 of rest part of FPCB306.In other embodiments, capacitance connector 316 may be embodied as relative to
The discontinuous 2nd FPCB panels of FPCB306.
In certain embodiments, including forward extension 306, (it can be embodied in preceding extension to the capacitor 353 shown in Figure 12 G
In panel, the first FPCB panels, the first FPCB elements etc.), it is preceding extension reinforcer part 308 (for example, first reinforcer part),
The preceding extension active pad 322 of capacitance touch (for example, capacitive character pad), (it can be embodied in capacitive character connector 316 to carrier layer 305B
Or in capacitive character connector panel, the 2nd FPCB panels, the 2nd FPCB elements etc.), capacitance joint reinforcing part part 320 is (for example,
Two reinforcer parts), signal protection part 310 (such as signal ground mouth) and be located in forepart extension reinforcer part 308 with
Adhesive (or double faced adhesive tape) 325 between capacitance joint reinforcing part part 320.Preceding extension reinforcer part 308, capacitance connector
Reinforcer part 320 and adhesive (or double faced adhesive tape) 325 are in the preceding extension active pad 322 of capacitance touch and signal protection part
Non-conductive separation is provided between 310.As shown in fig. 12g, carrier layer 305B (for example, 0.1 to 1.5mm is thick), forepart extension are strengthened
Part part 308 (such as 0.25 to 2.5mm thickness), capacitance joint reinforcing part part 320 (such as 0.25 to 2.5mm thickness) and adhesive
The active pad 322 of extension capacitance touch and signal protection before (or double faced adhesive tape) 325 (for example, 0.01 to 0.25mm) limits together
The distance between part 310 (for example, predetermined distance d in following equation 1) corresponds to scheduled capacitance, as follows:
In equation 1, L is the length of conducting element, and W is the width of conducting element, and Er is relative dielectric constant, and d
It is the dielectric thickness between conducting element.In one embodiment, length is about 3.0 centimetres, and width is about 2.0 centimetres, and
Thickness is about 0.75 to 1.00 millimeter.This provides about 25 to 33pF capacitance for capacitor 353.In certain embodiments, believe
Number guard member 310 can have the lateral dimension for the lateral dimension 20% to 40% for being more than the preceding extension active pad 322 of capacitance touch
(for example, width).First FPCB panels and the 2nd FPCB panels can include polyimides, and the first reinforcer part and the
Two reinforcer parts can have the dielectric constant of between 2.5 and 5 (such as between 4 and 4.5),
It should be noted that two reinforcers can be replaced using single reinforcer.For example, preceding extension reinforcer part
308 can be twice of thickness so that not need to capacitance joint reinforcing part part 320.Reinforcer (such as non-conductive space part)
Can be any non-conducting material (for example, foam, PCB etc.), and can be by fastener or adhesive (for example, glue, glue
Band etc.) it is attached to their own FPCB elements.Extension reinforcer part 308 and/or electricity before adhesive 325 can be applied to
In at least part for holding joint reinforcing part part 320.Further, it is possible to use any kind of adhesive 325 is (for example, two-sided
Adhesive tape, glue etc.), and the other kinds of attachment in addition to adhesive 325 can be used, such as fastener (such as spiral shell
Nail, nail etc.).In such a case, it is possible to omit adhesive 325.
In certain embodiments, capacitor 353 may be used as proximity sensor (for example, capacitance type sensor) so that light
Treating equipment 210 can be by the variation of capacitance and/or voltage (for example, the phase interaction due to the electric field with the skin close to patient
With) come determine phototherapy apparatus 210 whether close to patient forehead.In certain embodiments, the skin of patient can it is short away from
From far from changing capacitance (and generated voltage) in the case of without contacting capacitor 353.
The panel of panel sub-component 240 as flexible circuit is very thin (for example, about 0.10mm or smaller).Due to capacitance
Too high, the thickness is typically too thin and appropriate capacitance cannot be provided for proximity sensor.Therefore, folding capacitance connector 316 makes
Signal protection part 310 is aligned, and minimum range therebetween is by preceding extension reinforcer with the preceding extension active pad 322 of capacitance touch
Part 308, capacitance joint reinforcing part part 320 and/or adhesive (dielectric substance is preferably implemented in it) 325 are kept.Therefore, exist
Generated between the two conductive plates (for example, signal protection part 310 and the active pad 322 of preceding extension capacitance touch) bigger away from
From, and capacitance is changed.It is alternatively possible to by two plates (for example, signal protection part 310 and preceding extension condenser type
Touch active pad 322) between added material layer (for example, double faced adhesive tape 325) further adjust capacitance, wherein addition in this way
Material be preferably used as dielectric.
In certain embodiments, capacitor 353 provides two-way sensing function so that extension capacitance touch is active before only
The capacitance of pad 322 changes due to the close of its skin.In certain embodiments, signal protection part 310 can be configured as with
It is driven, and the size of signal protection part 310 can with the opposite polarity polarity of the preceding active liner 322 of extension capacitance touch
With the size bigger than the active pad 322 of preceding extension capacitance touch with the active pad 322 of extension capacitance touch before extending beyond
Edge.Which ensure that the degree of approach of skin to signal protection part 310 extends the electricity of the active pad 322 of capacitance touch before will not changing
Hold.In other words, the preceding extension active pad 322 of capacitance touch is configured as the capacitance change that sensing is originated from inside phototherapy apparatus 210
Change (since skin approaches), and signal protection part 310 prevents from detecting the approach signal of mistake (for example, from due to phototherapy
Capacitance variations caused by source outside equipment 210).This prevent touch the outside of phototherapy apparatus 210 (for example, capacitance connector
316) patient triggers the operation of phototherapy apparatus 210.Phototherapy apparatus 210 will be merely due to wear phototherapy apparatus 210 and (the example that is triggered
Such as, because of the capacitance that the skin of patient will change capacitor 353).Preceding extension signal protection part 310 can pattern together with copper
(such as with shade, grid etc.) is to form faraday cup, so that (it can include connecting the active pad 322 of preceding extension capacitance touch
Continuous (for example, solid copper) conductive surface) insulation.
Figure 12 H show the circuit 354 of capacitor 353 (or proximity sensor).It can be integrated circuit that circuit 354, which includes,
(IC) capacitive touch controller 355 (for example, microcontroller).Circuit 354 may be coupled to preceding extension capacitive touch and touch with
Source pad 322, signal protection part 310 and power circuit 356 (including positive voltage and ground connection).In addition, circuit 354 can connect
It is connected to one or more data sources 357 (for example, serial data line (SDA), serial time clock line (SCL) etc.) and interruption 358
(INT).When interrupt 358 be triggered when, interrupt 358 to mainboard send signal so that mainboard from dormant state (for example, in order to save
Electricity) into active state.In ambulatory situations, mainboard can check wireless (for example, bluetooth) signal and/or electrical connection, check
Account (for example, state) and/or the operation for enabling phototherapy apparatus 210.In certain embodiments, circuit 354 can keep continuous work
It is dynamic and provide feedback to controller so that when voltage and/or capacitance are such as since the capacitance variations of capacitor 353 are more than predetermined
Triggering interrupts 358 when being worth (for example, between 12-50pF).In some embodiments it is possible to via capacitive touch controller
355 adjust the threshold of sensitivity.
Figure 13 A and 13B show to wear and the patient of phototherapy apparatus 210 using Figure 10 A-10E.More specifically, Figure 13 A are
The front view of the patient of phototherapy apparatus 210 is worn, and Figure 13 B are the cross-sectional side views for the patient for wearing phototherapy apparatus 210.Such as
Shown in figure, the forepart of phototherapy apparatus 210 is located in the top of patient's eye, and the rear portion of phototherapy apparatus 210 is (for example, rear portion is prolonged
Extending portion) extend along the lower back portion on head so that the front base edge and rear base edge of phototherapy apparatus 210 are when in use
The height different in two.This allows phototherapy apparatus 210 to increase the overlay area of phototherapy apparatus 210 to cover patient's 360
The desired hair formation zone of scalp.As discussed above, flexible cap 212, FPCB components 214 and flexible biconvex lens 216
Size and shape can adjust (for example, perimeter can change) to adapt to various users.For example, interior perimeter can be at 54 centimetres
Change in 64 centimetres.
In use, the LED of phototherapy apparatus 210 provides therapeutic light emitting to the scalp 362 of patient 360.More specifically
Ground, for the optical transport of the LED in FPCB components proximal face 236 by flexible biconvex lens 216, this defocuses light emitting
To increase light emitting being uniformly distributed on patient's scalp 362.Although using flexible biconvex lens 216 in certain embodiments,
But other translucent materials or layer for including diffusing globe can be used.In order to which best light emitting distribution and performance are (for example, avoid
LED is positioned to too far from flexible biconvex lens 216 or too near), flexible biconvex lens 216 is preferably positioned on away from LED's
At preset distance, and safe distance is kept between the scalp 362 and LED (for example, heat that LED is generated) of patient.It should be away from
It is kept from (for example, in certain embodiments, 3.5mm between LED and flexible biconvex lens 216) by multiple stent 218a, 218b,
Wherein gravity promotes FPCB components 214 towards flexible biconvex lens 216 and multiple stent 218a, 218b contact FPCB naturally
Component 214 (is protected, for optical optimization and/or for hot from the scalp of patient with the minimum range of holding therebetween for LED
Separation).
In certain embodiments, LED can provide such as about 620nm to 660nm and/or 660nm to one of 670nm etc. or
More peak wavelengths (for example, red emission and/or blue emission) etc..For example, multiple LED can include generation about
420nm and 620nm or 420nm and 660nm or 420nm, 625nm and 660nm peak wavelength LED.
Figure 14 A-14D are the views of packaging and phototherapy apparatus.More specifically, Figure 14 A are the packagings for including phototherapy apparatus
Perspective upper view.Figure 14 B be by top cover from bottom cover removal after packaging and phototherapy apparatus decomposition perspective view (for
The purpose of explanation, top cover is transparent).Figure 14 C are the decomposition of the packaging of the phototherapy apparatus with Figure 14 A and 14B
View (for illustrative purposes, top cover is transparent).Figure 14 D are the side viewgraph of cross-section of the phototherapy apparatus of packaging.
The equipment 400 of packaging include top cover 402, bottom cover 404, charging base 406 therebetween and positioned at bottom cover 404 with charging
Accessory case 408 between pedestal 406, wherein phototherapy apparatus 410 are located on charging base 406 in charging base 406 and top
Between portion's covering 402.
Top cover 402 can be configured to variously-shaped and size.In certain embodiments, top cover 402
It can include roof 412, roof 412 has the side wall 416 extended downwardly from its periphery.In certain embodiments, side wall can be with
It is connect including string holes 418 with receiving the electric power connector passed through with phototherapy apparatus 410.In certain embodiments, top
Covering 402 can include one or more positioning tabs of near the opening of top cover 402 (but having distance)
420, receive a part for bottom cover 404 to provide enough gaps.Positioning tabs 420 are helped to stablize phototherapy apparatus 410 and be prevented
Only its transverse shifting.In certain embodiments, top cover 402 can include with bottom wall 424 and prolong upwards from its periphery
The insertion piece 422 for the side wall 426 stretched.Insertion piece 422 includes mesopore 428 in its approximate center, to receive phototherapy wherein
The part at the top of equipment 410.Therefore, top cover insertion piece 422 prevents the transverse shifting of phototherapy apparatus 410, and
Phototherapy apparatus 410 is fixed between insertion piece 422 and charging base 406.
Bottom cover 404 can be arranged to variously-shaped and size.Bottom cover 404 can include bottom wall 430, bottom wall 430 have from
The side wall 432 that its periphery upwardly extends.In certain embodiments, bottom cover 404 may include insertion piece 434, and insertion piece 434 has bottom
Wall 436, along its outer periphery outer wall 438 and along inner circumference and limit internal holes 442 (extending through bottom wall 436) it is interior
Wall 440.In certain embodiments, insertion piece outer wall 438 can be than 432 higher of bottom cover side wall so that insertion piece outer wall 438 contacts
Top cover 402 (to be frictionally fixed to the upper and prevented lateral shifting therebetween by the inside of top cover side wall 416
It is dynamic).Bottom cover insertion piece inner wall 440 can receive accessory case 408 (accessory case 408 to be frictionally fixed to wherein simultaneously wherein
Prevent transverse shifting therebetween).Accessory case 408 can include top packet, USB cable, AC adapters etc..
Figure 15 A-15D are the views of charging base 406.More specifically, Figure 15 A are the charging bottoms of the phototherapy apparatus of packaging
The perspective upper view of seat, Figure 15 B are the lower perspective views of charging base, and Figure 15 C are the side views of charging base, and Figure 15 D are to fill
The top plan view of electric pedestal.Charging base 406 may include the pedestal 444 with the shape complementation of bottom cover insertion piece outer wall 438
(frictionally be fixed to the upper charging base 406 and prevent transverse shifting therebetween).In certain embodiments, charging bottom
Seat 406 can be included in the recess 446 in the leading edge of pedestal 444, (scheme in order to remove charging base 406 from bottom cover 404
It shows and is discussed above in 14A-14D).In certain embodiments, charging base 406 can be included from charging base 406
One or more footing 448 of bottom surface extension.Footing 448 can be integrally formed with pedestal 444 or be attached to pedestal 444.
Pedestal 444 has wave tops 452 substantially consistent with the shape of the proximal face of phototherapy apparatus 410 (for example, convex
The top risen), and pedestal 444 can include antelabium 450, the periphery edge 410 substantially one of the antelabium 450 and phototherapy apparatus
It causes.Therefore, the contoured top 452 of charging base 406 and antelabium 450 stablize phototherapy apparatus 410 when placed thereon.In addition,
Contoured top 452 is inscribed in the inside limited by contoured top 452 receives accessory case 408.Charging base 406 can be used for without using
When and/or charging when keep phototherapy apparatus 410, so as to phototherapy apparatus 410 is supported in a manner of shielded and prevent its shape become
Shape.In certain embodiments, charging base 406 can be provided when phototherapy apparatus 410 is located in thereon passes through contoured top
The radio induction charging of 452 pairs of phototherapy apparatus 410.
Those skilled in the art will appreciate that improvement and modification to preferred embodiment of the present disclosure.All such improvement
It is considered in the range of concept and following claims disclosed herein with modification.
Claims (38)
1. a kind of for light emitting to be delivered to the phototherapy apparatus of the scalp of patient, the phototherapy apparatus includes:
Flexible printed circuit board (FPCB), the flexible printed circuit board include proximal face, and the proximal face is supported on institute
Stating has at least one luminaire of transmitter height above proximal face, wherein, the FPCB includes multiple interconnection panels
With at least some interconnection panels be limited at least some of the multiple interconnection panel interconnection panel and described it
Between multiple bending regions, the FPCB to be allowed to provide concave shape to cover at least part of the calvarium of patient;
At least one photic zone, at least one photic zone are disposed adjacent to the FPCB and are configured as transmission by institute
State at least some light emittings that at least one luminaire generates;And
Multiple stents, the multiple stent are arranged between the FPCB and the scalp of patient, wherein, it is the multiple
At least some of stent stent includes the support height more than the transmitter height.
2. phototherapy apparatus according to claim 1, further includes covering, the covering includes being arranged over described
Foam, fabric or the flexiplast of FPCB.
3. phototherapy apparatus according to claim 1, wherein, the FPCB is arranged to adaptation and expands outwardly and inwardly receive
Contracting.
4. phototherapy apparatus according to claim 1, further includes power circuit, the power circuit is arranged to provide at least
One power signal after the adjustment, for by the microcontroller of the phototherapy apparatus or at least one luminaire extremely
A few use, wherein, in the access times specified for detecting the phototherapy apparatus, the phototherapy apparatus is instructed to prevent
The further operating of the phototherapy apparatus.
5. phototherapy apparatus according to claim 1, wherein, at least one luminaire includes incoherent shine and sets
It is standby.
6. phototherapy apparatus according to claim 1, wherein, at least one luminaire includes being arranged to generation tool
There is the first luminaire array of the light of the first peak wavelength and be arranged to and generate second of the light with the second peak wavelength
Luminaire array, wherein, second peak wavelength differs at least 20nm with first peak wavelength.
7. phototherapy apparatus according to claim 6, wherein, first peak wavelength and second peak wavelength be from
Combine what is selected in a combination in (a) to (f) below:
(a) first peak wavelength is in the range of 615nm to 635nm, and second peak wavelength in 650nm extremely
In the range of 670nm;
(b) first peak wavelength is in the range of 520nm to 540nm, and second peak wavelength in 650nm extremely
In the range of 670nm;
(c) first peak wavelength is in the range of 410nm to 430nm, and second peak wavelength in 620nm extremely
In the range of 640nm;
(d) first peak wavelength is in the range of 410nm to 430nm, and second peak wavelength in 650nm extremely
In the range of 670nm;
(e) first peak wavelength is in the range of 410nm to 430nm, and second peak wavelength in 495nm extremely
In the range of 515nm;Or
(f) first peak wavelength is in the range of 410nm to 430nm, and second peak wavelength in 520nm extremely
In the range of 540nm.
8. phototherapy apparatus according to claim 1, further includes proximity sensor, the proximity sensor is arranged to sense
Indicate the situation of placement of the phototherapy apparatus close to the scalp of patient, wherein, the operation of at least one luminaire
Start, terminate or at least one of modification is in response to output signal in the proximity sensor.
9. phototherapy apparatus according to claim 1, further includes temperature sensor, the temperature sensor is arranged to sensing
Temperature regime on or near a part for the phototherapy apparatus, wherein, the startup of the operation of at least one luminaire,
At least one of the deviation of operation or the termination of operation are in response to the output signal in the temperature sensor.
10. phototherapy apparatus according to claim 1, wherein, the multiple stent is integrated at least one photic zone
Together.
11. phototherapy apparatus according to claim 1, wherein, from the proximal end of at least some of the multiple stent stent
Distance to the proximal face of the FPCB is more than at least one euphotic thickness.
12. phototherapy apparatus according to claim 1, wherein, the multiple stent be located in the FPCB with it is described extremely
Between a few photic zone.
13. phototherapy apparatus according to claim 1, wherein, at least one photic zone includes flexible biconvex lens.
14. phototherapy apparatus according to claim 1, further include communication module, the communication module be configured as with it is described
Electronic equipment outside phototherapy apparatus carries out electronic communication.
15. a kind of for light emitting to be delivered to the phototherapy apparatus of the scalp of patient, the phototherapy apparatus includes:
Flexible substrate, the flexible substrate include the proximal face for supporting at least one luminaire array;
Photic zone, the photic zone are configured to transmission at least some light as caused by least one luminaire array
Transmitting;
Multiple stents, the multiple stent are positioned between the flexible substrate and the scalp of patient;
Energy storage elements;
Drive circuit, the drive circuit are arranged to that driving institute is electrically connected and be configured as with the energy storage elements
State at least one luminaire array;And
Covering, the covering are arranged to the covering flexible substrate;
Wherein, the flexible substrate and the covering are arranged to adaptation and expand outwardly and to contract, to allow the light
It is adjustably to fit to the head of patient to treat equipment.
16. phototherapy apparatus according to claim 15, wherein, the covering includes foam, fabric or flexiplast shell
Body.
17. it is a kind of for light emitting to be delivered to the phototherapy apparatus of the scalp of patient, including:
Flexible lens, the flexible lens include proximal lens surface and distal lens surface;
Flexible printed circuit board (FPCB), the flexible printed circuit board are included in the flexible printed circuit board proximal face
At least one luminaire;With
Multiple stents, the multiple stent are positioned between the distal lens surface and the FPCB, with it is described at least
Keep minimum range between one luminaire and the distal lens surface, wherein, the phototherapy apparatus be configured to by by
The light emitting that at least one luminaire generates is transmitted to the scalp of patient by the flexible lens.
18. phototherapy apparatus according to claim 17, wherein, from the proximal end of each stent of the multiple stent to described
The distance on the proximal lens surface of flexible lens is more than the thickness of the flexible lens.
19. phototherapy apparatus according to claim 17, wherein, the light emitting of at least one luminaire about exists
In the range of 410nm to 455nm.
20. phototherapy apparatus according to claim 17, wherein, the light emitting of at least one luminaire about exists
In the range of 620nm to 700nm.
21. a kind of method for treating at least one skin disorder, the method includes will be according to claim 17
Phototherapy apparatus is placed on the head of patient, and encourages at least one luminaire that light emitting is delivered to the head of patient
At least part of skin.
22. phototherapy apparatus according to claim 17, wherein, the FPCB is arranged to adaptation and expands outwardly and inwardly receive
Contracting.
23. phototherapy apparatus according to claim 17, wherein, at least one luminaire includes incoherent shine and sets
It is standby.
24. phototherapy apparatus according to claim 17, wherein, at least one luminaire includes being arranged to generation
First luminaire array of the light with the first peak wavelength and it is arranged to and generates the of the light with the second peak wavelength
Two luminaire arrays, wherein, second peak wavelength differs at least 20nm with first peak wavelength.
25. phototherapy apparatus according to claim 24, wherein, first peak wavelength and second peak wavelength are
It is selected from a combination in following combination (a) to (f):
(a) first peak wavelength is in the range of 615nm to 635nm, and second peak wavelength in 650nm extremely
In the range of 670nm;
(b) first peak wavelength is in the range of 520nm to 540nm, and second peak wavelength in 650nm extremely
In the range of 670nm;
(c) first peak wavelength is in the range of 410nm to 430nm, and second peak wavelength in 620nm extremely
In the range of 640nm;
(d) first peak wavelength is in the range of 410nm to 430nm, and second peak wavelength in 650nm extremely
In the range of 670nm;
(e) first peak wavelength is in the range of 410nm to 430nm, and second peak wavelength in 495nm extremely
In the range of 515nm;Or
(f) first peak wavelength is in the range of 410nm to 430nm, and second peak wavelength in 520nm extremely
In the range of 540nm.
26. phototherapy apparatus according to claim 17, further includes proximity sensor, the proximity sensor is arranged to sense
The situation for indicating placement of the phototherapy apparatus close to the scalp of patient is surveyed, wherein, the operation of at least one luminaire
At least one of startup, termination or modification be in response to output signal in the proximity sensor.
27. phototherapy apparatus according to claim 17, further includes temperature sensor, the temperature sensor is arranged to sense
The temperature regime on or near a part for the phototherapy apparatus is surveyed, wherein, the operation of at least one luminaire is opened
At least one of termination of dynamic, operation deviation or operation is in response to the output signal in the temperature sensor.
28. phototherapy apparatus according to claim 17, wherein, the flexible lens include flexible biconvex lens.
29. phototherapy apparatus according to claim 28, wherein, the multiple stent is integrally attached to the flexible biconvex
Lens.
30. phototherapy apparatus according to claim 29, wherein, the flexibility biconvex lens and the multiple stent are to pass through
It moulds and is formed.
31. phototherapy apparatus according to claim 17, further include communication module, the communication module be configured as with it is described
Electronic equipment outside phototherapy apparatus carries out electronic communication.
32. a kind of capacitor, including:
First flexible circuit panel element, including the first conductive material layer and the first dielectric material layer;
Second flexible circuit panel element, including the second conductive material layer and the second dielectric material layer;With
At least one spacer, at least one spacer are connected to the first flexible circuit panel element and described second soft
Between property circuit board component.
33. capacitor according to claim 32, wherein, at least one spacer has between about 2 to about 5 ranges
Interior dielectric constant values.
34. capacitor according to claim 32, wherein, at least one spacer is adhered to first flexible electrical
Between road panel element and the second flexible circuit panel element.
35. capacitor according to claim 32, wherein, it is flexible that the first flexible circuit panel element includes described second
Circuit board component is extended continuously part, and recurvate flexion zones are arranged in the first flexible circuit panel element and institute
It states between the second flexible circuit panel element.
36. capacitor according to claim 32, wherein, at least one spacer, first dielectric substance
Layer and second dielectric material layer are by the distance between first conductive material layer and second conductive material layer guarantor
It holds in the range of about 0.2mm to about 2mm.
37. capacitor according to claim 32, wherein, first conductive material layer has than second conduction material
The extending transversely of bed of material bigger.
38. a kind of proximity sensor for including capacitor according to claim 32.
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US201562197736P | 2015-07-28 | 2015-07-28 | |
US62/197,736 | 2015-07-28 | ||
PCT/US2016/044403 WO2017019839A1 (en) | 2015-07-28 | 2016-07-28 | Phototherapy devices for treatment of dermatological disorders of the scalp |
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CN108136199A true CN108136199A (en) | 2018-06-08 |
CN108136199B CN108136199B (en) | 2022-03-01 |
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CN201680054311.3A Active CN108136199B (en) | 2015-07-28 | 2016-07-28 | Phototherapy device for dermatological treatment of the scalp |
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US (6) | US10688315B2 (en) |
EP (2) | EP3851162A1 (en) |
CN (1) | CN108136199B (en) |
BR (1) | BR112018001857B1 (en) |
CA (1) | CA177607S (en) |
ES (1) | ES2836266T3 (en) |
WO (1) | WO2017019839A1 (en) |
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---|---|---|---|---|
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USD907858S1 (en) * | 2018-09-17 | 2021-01-12 | Park & Diamond, Inc. | Helmet |
USD962458S1 (en) * | 2018-10-17 | 2022-08-30 | Kumho Electric, Inc. | Scalp care device |
US11033752B2 (en) | 2018-10-22 | 2021-06-15 | Joovv, Inc. | Photobiomodulation therapy systems and methods |
US10478635B1 (en) | 2018-10-22 | 2019-11-19 | Joovv, Inc. | Photobiomodulation therapy systems and methods |
US11458328B2 (en) | 2018-10-22 | 2022-10-04 | Joovv, Inc. | Photobiomodulation therapy device accessories |
US11207543B2 (en) | 2018-10-22 | 2021-12-28 | Joovv, Inc. | Photobiomodulation therapy device accessories |
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US11147984B2 (en) | 2020-03-19 | 2021-10-19 | Know Bio, Llc | Illumination devices for inducing biological effects |
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US11654294B2 (en) | 2021-03-15 | 2023-05-23 | Know Bio, Llc | Intranasal illumination devices |
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USD998897S1 (en) * | 2021-11-30 | 2023-09-12 | Davinci Ii Csj, Llc | Helmet |
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USD1017817S1 (en) * | 2022-01-27 | 2024-03-12 | Dongguan Huifeng Technology Co., Ltd. | Physiotherapy lamp hat |
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Citations (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5616140A (en) * | 1994-03-21 | 1997-04-01 | Prescott; Marvin | Method and apparatus for therapeutic laser treatment |
US20020128648A1 (en) * | 1999-12-30 | 2002-09-12 | Pearl Technology Holdings Ii, Llc | Tissue-lifting device |
US20030076281A1 (en) * | 1997-08-26 | 2003-04-24 | Frederick Marshall Morgan | Diffuse illumination systems and methods |
US20060287696A1 (en) * | 2005-06-21 | 2006-12-21 | Wright David W | Heat and light therapy treatment device and method |
US20070179571A1 (en) * | 2006-01-30 | 2007-08-02 | Luis De Taboada | Light-emitting device and method for providing phototherapy to the brain |
US20080269849A1 (en) * | 2007-04-19 | 2008-10-30 | Mergenet Medical, Inc. | Temporal control in phototherapy |
CN101495182A (en) * | 2006-02-06 | 2009-07-29 | 法洛斯生命公司 | Therapy device and system and method for reducing harmful exposure to electromagnetic radiation |
CN101795634A (en) * | 2007-04-23 | 2010-08-04 | 透皮帽公司 | Phototherapy light cap |
CN102300606A (en) * | 2008-12-01 | 2011-12-28 | 安比卡尔保健有限公司 | Light Emitting Apparatus |
CN102348425A (en) * | 2006-03-10 | 2012-02-08 | 帕洛玛医疗技术公司 | Photocosmetic device |
CN102371031A (en) * | 2010-08-23 | 2012-03-14 | 汉唐集成股份有限公司 | Method and device for exciting brain waves by using light energy |
CN102380169A (en) * | 2011-10-28 | 2012-03-21 | 东莞市横沥天兆电子经营部 | LED (light emitting diode) hair increasing membrane |
CN102590899A (en) * | 2011-01-04 | 2012-07-18 | 三炬富工业股份有限公司 | Light equalizing lens |
CN203169848U (en) * | 2013-03-20 | 2013-09-04 | 东莞市朵露曼美光电子科技有限公司 | LED head membrane cap |
US20140128941A1 (en) * | 2012-11-08 | 2014-05-08 | Applied Biophotonics Ltd. | Phototherapy System And Process Including Dynamic LED Driver With Programmable Waveform |
CN103930162A (en) * | 2011-09-08 | 2014-07-16 | 拉卢米埃有限公司 | Light therapy platform system |
CN104167592A (en) * | 2009-07-17 | 2014-11-26 | 苹果公司 | Electronic devices with capacitive proximity sensors |
CN204317834U (en) * | 2014-12-22 | 2015-05-13 | 惠州市凯瑞科技有限公司 | A kind of cover used during hair washing with magnetic therapy functions |
Family Cites Families (136)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2333987A (en) * | 1941-06-18 | 1943-11-09 | Walter E Dandy | Protective cap |
USD267287S (en) | 1980-09-11 | 1982-12-21 | The Regents Of The University Of Michigan | Pneumatic liner for protective headgear |
USD369668S (en) | 1990-02-14 | 1996-05-07 | Branislav Stojanovic | Device for accumulating, amplifying and directing cosmical energy |
US5228431A (en) | 1990-04-26 | 1993-07-20 | Giarretto Ralph R | Drug-free method for treatment of the scalp for therapeutic purposes |
GB2272278B (en) | 1992-10-23 | 1997-04-09 | Cancer Res Campaign Tech | Light source |
USD348520S (en) | 1992-11-20 | 1994-07-05 | Owen Wolf | Therapeutic appliance for stress relief |
US5549639A (en) | 1994-09-16 | 1996-08-27 | Sandia Corporation | Non-invasive hyperthermia apparatus including coaxial applicator having a non-invasive radiometric receiving antenna incorporated therein and method of use thereof |
USD382671S (en) * | 1996-02-12 | 1997-08-19 | Biokinetics And Associates Ltd. | Helmet |
RU2145247C1 (en) | 1998-04-10 | 2000-02-10 | Жаров Владимир Павлович | Photomatrix therapeutic device for treatment of extended pathologies |
IL124722A0 (en) | 1998-06-02 | 1999-01-26 | Oron Amir | Ischemia laser treatment |
US6096066A (en) | 1998-09-11 | 2000-08-01 | Light Sciences Limited Partnership | Conformal patch for administering light therapy to subcutaneous tumors |
US20060212025A1 (en) | 1998-11-30 | 2006-09-21 | Light Bioscience, Llc | Method and apparatus for acne treatment |
US6676655B2 (en) | 1998-11-30 | 2004-01-13 | Light Bioscience L.L.C. | Low intensity light therapy for the manipulation of fibroblast, and fibroblast-derived mammalian cells and collagen |
US6887260B1 (en) | 1998-11-30 | 2005-05-03 | Light Bioscience, Llc | Method and apparatus for acne treatment |
US9192780B2 (en) | 1998-11-30 | 2015-11-24 | L'oreal | Low intensity light therapy for treatment of retinal, macular, and visual pathway disorders |
US6663659B2 (en) | 2000-01-13 | 2003-12-16 | Mcdaniel David H. | Method and apparatus for the photomodulation of living cells |
US6283956B1 (en) | 1998-11-30 | 2001-09-04 | David H. McDaniels | Reduction, elimination, or stimulation of hair growth |
US6936044B2 (en) | 1998-11-30 | 2005-08-30 | Light Bioscience, Llc | Method and apparatus for the stimulation of hair growth |
US6290713B1 (en) | 1999-08-24 | 2001-09-18 | Thomas A. Russell | Flexible illuminators for phototherapy |
GB2360459B (en) | 2000-03-23 | 2002-08-07 | Photo Therapeutics Ltd | Therapeutic light source and method |
US7201764B2 (en) | 2001-03-06 | 2007-04-10 | Lexington Lasercomb Ip Ag | Apparatus and method for stimulating hair growth |
US9561386B2 (en) | 2001-03-06 | 2017-02-07 | Lexington International, Llc | Apparatus and method for stimulating hair growth |
US8771327B2 (en) | 2001-03-06 | 2014-07-08 | Lexington Lasercomb Ipag | Apparatus and method for stimulating hair growth |
US6497719B2 (en) | 2001-03-06 | 2002-12-24 | Henry Pearl | Apparatus and method for stimulating hair growth |
EP1414516A2 (en) | 2001-06-26 | 2004-05-06 | Photomed Technologies, Inc. | Therapeutic methods using electromagnetic radiation |
US7303578B2 (en) | 2001-11-01 | 2007-12-04 | Photothera, Inc. | Device and method for providing phototherapy to the brain |
US20040162596A1 (en) | 2002-10-07 | 2004-08-19 | Palomar Medical Technologies, Inc. | Methods and apparatus for performing photobiostimulation |
US7081128B2 (en) | 2002-03-04 | 2006-07-25 | Hart Barry M | Phototherapy device and method of use |
US6955684B2 (en) | 2002-03-29 | 2005-10-18 | Savage Jr Henry C | Portable light delivery apparatus and methods |
US20030236487A1 (en) | 2002-04-29 | 2003-12-25 | Knowlton Edward W. | Method for treatment of tissue with feedback |
US7304201B2 (en) | 2002-06-12 | 2007-12-04 | University Of Florida Research Foundation, Inc. | Phototherapy bandage |
JP2005535370A (en) | 2002-06-19 | 2005-11-24 | パロマー・メディカル・テクノロジーズ・インコーポレイテッド | Method and apparatus for treating skin and subcutaneous conditions |
US6860896B2 (en) | 2002-09-03 | 2005-03-01 | Jeffrey T. Samson | Therapeutic method and apparatus |
US20070213792A1 (en) | 2002-10-07 | 2007-09-13 | Palomar Medical Technologies, Inc. | Treatment Of Tissue Volume With Radiant Energy |
US7931028B2 (en) | 2003-08-26 | 2011-04-26 | Jay Harvey H | Skin injury or damage prevention method using optical radiation |
AU2003291469A1 (en) * | 2002-11-12 | 2004-06-03 | Palomar Medical Tech Inc | Apparatus for performing optical dermatology |
US7267673B2 (en) | 2002-12-12 | 2007-09-11 | Pacific Biosciences Laboratories, Inc. | System for treatment of acne skin condition using a narrow band light source |
CA2531099A1 (en) | 2003-04-10 | 2004-10-28 | Light Bioscience, Llc | Photomodulation methods and devices for regulating cell proliferation and gene expression |
US6989023B2 (en) | 2003-07-08 | 2006-01-24 | Oralum, Llc | Hygienic treatments of body structures |
CN101247768A (en) | 2003-07-31 | 2008-08-20 | 莱特生物科学有限公司 | System and method for the photodynamic treatment of burns, wounds, and related skin disorders |
CN100577236C (en) | 2003-08-18 | 2010-01-06 | 皇家飞利浦电子股份有限公司 | Device and method for low intensity optical hair growth control |
US20050143792A1 (en) * | 2003-12-24 | 2005-06-30 | Harvey Jay | Hair treatment method |
KR101277022B1 (en) | 2004-08-06 | 2013-06-24 | 파로스 라이프 코오포레이션 | Therapy device and related accessories, compositions, and treatment methods |
US20060030908A1 (en) | 2004-08-09 | 2006-02-09 | Lumiport, Llc | Skin treatment phototherapy device |
US20070248930A1 (en) | 2005-02-17 | 2007-10-25 | Biolux Research Ltd. | Light therapy apparatus and methods |
US20090319008A1 (en) | 2005-03-31 | 2009-12-24 | Esther Mayer | Probe device, system and method for photobiomodulation of tissue lining a body cavity |
US7460578B2 (en) * | 2005-04-11 | 2008-12-02 | Finisar Corporation | On-chip lenses for diverting vertical cavity surface emitting laser beams |
CA2504857A1 (en) * | 2005-04-22 | 2006-10-22 | Infinity Brands Inc. | Portable rechargeable therapeutic device and method of using the same |
BRPI0616167A2 (en) | 2005-09-15 | 2011-06-07 | Palomar Medical Tech Inc | optical skin characterization device |
JP4713304B2 (en) | 2005-11-07 | 2011-06-29 | 富士通テン株式会社 | Data management device |
USD536814S1 (en) | 2005-11-14 | 2007-02-13 | Hjc Co. Ltd. | LED lamp for helmet |
US10695579B2 (en) | 2006-01-30 | 2020-06-30 | Pthera LLC | Apparatus and method for indicating treatment site locations for phototherapy to the brain |
US20070208396A1 (en) | 2006-03-03 | 2007-09-06 | Gary Whatcott | Systems and methods for providing a dynamic light pad |
WO2007106856A2 (en) * | 2006-03-14 | 2007-09-20 | Allux Medical, Inc. | Phototherapy device and method of providing phototherapy to a body surface |
US20070233208A1 (en) | 2006-03-28 | 2007-10-04 | Eastman Kodak Company | Light therapy bandage with imbedded emitters |
EP2029229A1 (en) | 2006-06-07 | 2009-03-04 | Koninklijke Philips Electronics N.V. | Light device and method of manufacturing a light device |
USD556951S1 (en) * | 2006-07-07 | 2007-12-04 | Ricky James Gath | Sports helmet |
US20080269848A1 (en) | 2007-04-24 | 2008-10-30 | Conopco, Inc. D/B/A Unilever | Scalp treatment device |
US20100331928A1 (en) | 2007-05-11 | 2010-12-30 | Clarimedix | Visible light modulation of mitochondrial function in hypoxia and disease |
US20080319430A1 (en) | 2007-06-21 | 2008-12-25 | Palomar Medical Technologies, Inc. | Eye-Safe Device For Treatment Of Skin Tissue |
US8146607B2 (en) | 2007-08-01 | 2012-04-03 | Rabin Michael I | Ventilated device for delivery of agents to and through the human scalp |
GB0718677D0 (en) * | 2007-09-25 | 2007-10-31 | 3M Innovative Properties Co | Capacitive sensor and proximity detector using it |
WO2009088550A2 (en) | 2007-10-19 | 2009-07-16 | Lockheed Martin Corporation | System and method for conditioning animal tissue using laser light |
US8280484B2 (en) | 2007-12-18 | 2012-10-02 | The Invention Science Fund I, Llc | System, devices, and methods for detecting occlusions in a biological subject |
US8641702B2 (en) | 2008-01-04 | 2014-02-04 | L'oreal | System for treatment of skin conditions using at least one narrow band light source in a skin brush having an oscillating brushhead |
US20090177253A1 (en) * | 2008-01-08 | 2009-07-09 | Oregon Aesthetic Technologies | Skin therapy system |
KR100971358B1 (en) | 2008-07-01 | 2010-07-20 | 광주과학기술원 | Invasive Dual-wavelength Laser Acupuncture |
US8192473B2 (en) | 2008-09-19 | 2012-06-05 | Apira Science, Inc. | Phototherapy apparatus for hair, scalp and skin treatment |
US20110160814A2 (en) * | 2008-09-19 | 2011-06-30 | Apira Science, Inc. | Phototherapy apparatus for hair, scalp and skin treatment |
US20120065709A1 (en) | 2008-09-30 | 2012-03-15 | The Regents Of The University Of Colorado | Methods and devices for visible light modulation of mitochondrial function in hypoxia and disease |
USD599954S1 (en) | 2009-02-24 | 2009-09-08 | Lexington Lasercomb Ipag | Laser comb |
US20100242155A1 (en) | 2009-03-25 | 2010-09-30 | Carullo Jr John F | Headgear equipped with laser hair care apparatus |
CN102448372B (en) | 2009-06-03 | 2014-09-24 | 皇家飞利浦电子股份有限公司 | Titrating a phototherapy regime using real-time eeg readings |
FR2946845B1 (en) | 2009-06-18 | 2011-08-19 | Oreal | DEVICE FOR TREATING HUMAN KERATINIC MATERIALS |
US9415237B2 (en) | 2009-06-30 | 2016-08-16 | Koninklijke Philips N.V. | Light treatment system |
USD631604S1 (en) | 2009-08-10 | 2011-01-25 | Lexington Lasercomb Ipag | Laser comb |
US8690933B2 (en) | 2009-08-31 | 2014-04-08 | Brigham Young University | System and method for treating symptoms of restless legs syndrome |
US8747446B2 (en) | 2009-10-12 | 2014-06-10 | Chung-Yang Chen | Hair restoration caring device |
USD631971S1 (en) | 2009-10-27 | 2011-02-01 | Anodyne Therapy, L.L.C. | Plantar fasciitus IR-LED apparatus |
US20120059440A1 (en) | 2009-11-25 | 2012-03-08 | Theradome Inc. | Portable light hair restoration helmet |
US9833633B2 (en) | 2009-11-25 | 2017-12-05 | Theradome, Inc. | Laser phototherapy device for illumination of the scalp to promote hair growth |
US20150005854A1 (en) | 2013-06-27 | 2015-01-01 | Hamid Tamim Said | Portable light hair restoration helmet |
US20110144727A1 (en) | 2009-12-15 | 2011-06-16 | Mellen Thomas Benedict | Portable phototherapy device and method for using a portable therapy device |
US9215921B2 (en) | 2010-01-06 | 2015-12-22 | L'oreal | Packaging and applicator device including an applicator member |
FR2956817B1 (en) | 2010-02-26 | 2020-11-20 | Oreal | USE OF ORIGAN OR ROSEWOOD ESSENTIAL OIL, OR THEIR CONSTITUENTS, IN THE THERAPEUTIC TREATMENT OF KERATOSES |
WO2011153328A1 (en) | 2010-06-02 | 2011-12-08 | Nike International, Ltd. | Light therapy systems and methods |
CN103025380A (en) | 2010-08-11 | 2013-04-03 | 皇家飞利浦电子股份有限公司 | Phototherapy method and device |
EP2605829B1 (en) | 2010-08-17 | 2017-12-06 | Koninklijke Philips N.V. | Flexible light therapy device, a plaster and a bandage |
USD635686S1 (en) | 2010-09-03 | 2011-04-05 | Apira Science, Inc. | Phototherapy device |
USD639751S1 (en) | 2010-09-16 | 2011-06-14 | Apira Science, Inc. | Phototherapy control device |
USD640793S1 (en) | 2010-11-12 | 2011-06-28 | James Britt | Portable therapeutic light device |
USD682437S1 (en) | 2010-12-13 | 2013-05-14 | Venous Health Systems, Inc. | Constellation of chambers for distributing pneumatic pressure |
CN103269751B (en) | 2010-12-21 | 2016-10-05 | 皇家飞利浦电子股份有限公司 | Light therapy apparatus |
EP2508229A1 (en) | 2011-04-07 | 2012-10-10 | Koninklijke Philips Electronics N.V. | Method and device for biostimulating irradiation |
CN102247656A (en) | 2011-04-07 | 2011-11-23 | 顾英 | Novel light-emitting diode (LED) phototherapy health-care device |
USD670869S1 (en) | 2011-05-09 | 2012-11-13 | A7 Helmet Systems, Llc | Helmet padding |
EP2540345A1 (en) | 2011-06-28 | 2013-01-02 | Koninklijke Philips Electronics N.V. | Device for light therapy with improved wearing comfort |
US20130041432A1 (en) | 2011-08-08 | 2013-02-14 | Gavin Tucker | Device for promoting growth of eyebrow hair |
US10434325B2 (en) | 2011-09-08 | 2019-10-08 | Johnson & Johnson Consumer Inc. | Light therapy platform mobile device applications |
US9789333B2 (en) * | 2011-09-08 | 2017-10-17 | Johnson & Johnson Consumer Inc. | Light therapy platform system |
US9467141B2 (en) * | 2011-10-07 | 2016-10-11 | Microchip Technology Incorporated | Measuring capacitance of a capacitive sensor with a microcontroller having an analog output for driving a guard ring |
CA2854923C (en) | 2011-11-08 | 2021-10-19 | Biophotas, Inc. | Shapeable light therapy device and method |
USD669638S1 (en) | 2012-02-28 | 2012-10-23 | Mark Martinez | Helmet |
USD704338S1 (en) | 2012-04-17 | 2014-05-06 | Orfit Industries | Radiotherapy mask |
US8702772B2 (en) * | 2012-09-11 | 2014-04-22 | Derma Dream Group Ltd. | Device for dermatological use with a failsafe control |
US9295854B2 (en) | 2012-11-28 | 2016-03-29 | Point Source, Inc. | Light and bioelectric therapy pad |
CA151931S (en) | 2013-01-09 | 2014-06-06 | Philips Electronics Ltd | Light therapy device |
US9636521B2 (en) * | 2013-07-12 | 2017-05-02 | Jonathan Isserow | Heat and light treatment device using nanotechnology |
US20140243933A1 (en) | 2013-02-25 | 2014-08-28 | Medos International Sarl | Modulation of the Activity of Mitochondria in Brown Adipose Tissue By Photobiomodulation for the Treatment of Obesity |
USD695966S1 (en) | 2013-03-06 | 2013-12-17 | Pse Technology, Llc | Head protective gear |
CN103169848A (en) | 2013-03-11 | 2013-06-26 | 刘晓燕 | Traditional Chinese medicine for treating intractable aphtha |
WO2014146029A1 (en) | 2013-03-15 | 2014-09-18 | Jones Gary W | Multispectral therapeutic light source |
DK3446743T3 (en) | 2013-03-15 | 2020-12-14 | Carewear Corp | Ultrasonic transducer device |
WO2014169006A1 (en) | 2013-04-09 | 2014-10-16 | Haarlander Michael E | Phototherapy device |
US20140350643A1 (en) | 2013-05-23 | 2014-11-27 | Apira Science, Inc. | Phototherapy apparatus for skin treatment |
WO2014204511A2 (en) * | 2013-06-18 | 2014-12-24 | Isonea Limited | Compliance monitoring for asthma inhalers |
US20160151639A1 (en) | 2013-07-10 | 2016-06-02 | Oxys Ag | Devices and methods for delivery of therapeutic energy |
USD724232S1 (en) * | 2013-08-29 | 2015-03-10 | Pediatric Innovations USA, LLC | Therapeutic helmet |
US20150112411A1 (en) | 2013-10-18 | 2015-04-23 | Varaya Photoceuticals, Llc | High powered light emitting diode photobiology compositions, methods and systems |
US20150127072A1 (en) * | 2013-11-07 | 2015-05-07 | Espansione Marketing S.P.A. | Device for emitting light by means of leds of the continuous and pulsed type for aesthetic and therapeutic treatments |
US9724536B1 (en) | 2014-04-22 | 2017-08-08 | Michael I. Rabin | Embedded fiber phototherapy light cap |
USD716493S1 (en) | 2014-06-09 | 2014-10-28 | Lexington International, Llc | Laser comb |
USD762870S1 (en) | 2014-07-30 | 2016-08-02 | Vijay Singh | LED light therapy tape |
USD754897S1 (en) | 2014-10-20 | 2016-04-26 | Lexington International, Llc | Light emitting hands free unit |
JP2017530850A (en) | 2014-10-20 | 2017-10-19 | レキシントン インターナショナル エルエルシーLexington International,LLC | Hands-free light emitting device |
US9616013B2 (en) | 2014-12-24 | 2017-04-11 | L'oreal | Photo-activated hydrogels |
USD790723S1 (en) | 2015-03-18 | 2017-06-27 | Courtney Ventures Inc. | Phototherapy mask |
US10099065B2 (en) * | 2015-03-20 | 2018-10-16 | Capillus, Llc | Laser therapy apparatus and method |
EP3069762B1 (en) | 2015-03-20 | 2018-08-08 | Capillus LLC | Laser therapy apparatus |
AU2016100390A4 (en) | 2015-03-20 | 2016-07-07 | Capillus Llc | Laser therapy apparatus and method |
USD778456S1 (en) | 2015-04-07 | 2017-02-07 | Meditech International Inc. | Treatment head |
USD763461S1 (en) * | 2015-05-28 | 2016-08-09 | Shenzhen Breo Technology Co., Ltd. | Head massager |
CN111701144B (en) | 2015-07-28 | 2023-03-21 | 诺欧生物有限责任公司 | Systems and methods for phototherapy modulation of nitric oxide |
USD777339S1 (en) | 2015-11-12 | 2017-01-24 | Wellmike Technology Corporation | Wearable phototherapy apparatus for hair and scalp treatment |
USD804047S1 (en) | 2016-04-08 | 2017-11-28 | Lexington International, Llc | Curved light emitting hands free device |
USD812308S1 (en) * | 2016-10-03 | 2018-03-06 | Revision Military S.A.R.L. | Helmet |
-
2016
- 2016-07-28 WO PCT/US2016/044403 patent/WO2017019839A1/en active Application Filing
- 2016-07-28 EP EP20194978.1A patent/EP3851162A1/en active Pending
- 2016-07-28 CN CN201680054311.3A patent/CN108136199B/en active Active
- 2016-07-28 BR BR112018001857-0A patent/BR112018001857B1/en active IP Right Grant
- 2016-07-28 US US15/222,292 patent/US10688315B2/en active Active
- 2016-07-28 EP EP16831334.4A patent/EP3328492B8/en active Active
- 2016-07-28 ES ES16831334T patent/ES2836266T3/en active Active
-
2017
- 2017-04-13 US US29/600,518 patent/USD849959S1/en active Active
- 2017-10-10 CA CA177607F patent/CA177607S/en active Active
-
2020
- 2020-05-27 US US16/884,858 patent/US11400309B2/en active Active
-
2022
- 2022-05-23 US US17/750,872 patent/US20220280809A1/en active Pending
-
2023
- 2023-05-11 US US18/315,819 patent/US20230277867A1/en active Pending
- 2023-05-11 US US18/315,795 patent/US20230310880A1/en active Pending
Patent Citations (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5616140A (en) * | 1994-03-21 | 1997-04-01 | Prescott; Marvin | Method and apparatus for therapeutic laser treatment |
US20030076281A1 (en) * | 1997-08-26 | 2003-04-24 | Frederick Marshall Morgan | Diffuse illumination systems and methods |
US20020128648A1 (en) * | 1999-12-30 | 2002-09-12 | Pearl Technology Holdings Ii, Llc | Tissue-lifting device |
US20060287696A1 (en) * | 2005-06-21 | 2006-12-21 | Wright David W | Heat and light therapy treatment device and method |
US20070179571A1 (en) * | 2006-01-30 | 2007-08-02 | Luis De Taboada | Light-emitting device and method for providing phototherapy to the brain |
CN101495182A (en) * | 2006-02-06 | 2009-07-29 | 法洛斯生命公司 | Therapy device and system and method for reducing harmful exposure to electromagnetic radiation |
CN102348425A (en) * | 2006-03-10 | 2012-02-08 | 帕洛玛医疗技术公司 | Photocosmetic device |
US20080269849A1 (en) * | 2007-04-19 | 2008-10-30 | Mergenet Medical, Inc. | Temporal control in phototherapy |
CN101795634A (en) * | 2007-04-23 | 2010-08-04 | 透皮帽公司 | Phototherapy light cap |
CN102300606A (en) * | 2008-12-01 | 2011-12-28 | 安比卡尔保健有限公司 | Light Emitting Apparatus |
CN104167592A (en) * | 2009-07-17 | 2014-11-26 | 苹果公司 | Electronic devices with capacitive proximity sensors |
CN102371031A (en) * | 2010-08-23 | 2012-03-14 | 汉唐集成股份有限公司 | Method and device for exciting brain waves by using light energy |
CN102590899A (en) * | 2011-01-04 | 2012-07-18 | 三炬富工业股份有限公司 | Light equalizing lens |
CN103930162A (en) * | 2011-09-08 | 2014-07-16 | 拉卢米埃有限公司 | Light therapy platform system |
CN102380169A (en) * | 2011-10-28 | 2012-03-21 | 东莞市横沥天兆电子经营部 | LED (light emitting diode) hair increasing membrane |
US20140128941A1 (en) * | 2012-11-08 | 2014-05-08 | Applied Biophotonics Ltd. | Phototherapy System And Process Including Dynamic LED Driver With Programmable Waveform |
CN203169848U (en) * | 2013-03-20 | 2013-09-04 | 东莞市朵露曼美光电子科技有限公司 | LED head membrane cap |
CN204317834U (en) * | 2014-12-22 | 2015-05-13 | 惠州市凯瑞科技有限公司 | A kind of cover used during hair washing with magnetic therapy functions |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109289128A (en) * | 2018-08-29 | 2019-02-01 | 南京新生医疗科技有限公司 | Laser hair care all-in-one machine |
CN109771841A (en) * | 2019-03-16 | 2019-05-21 | 张倜然 | A kind of baldness therapeutic device and its application method |
CN110538384A (en) * | 2019-09-12 | 2019-12-06 | 黄斌 | Health-care luminous cap |
CN110538384B (en) * | 2019-09-12 | 2022-08-09 | 黄斌 | Health-care luminous cap |
CN110665126A (en) * | 2019-10-09 | 2020-01-10 | 丹阳慧创医疗设备有限公司 | Equipment and system for transcranial light regulation and control |
CN110975167A (en) * | 2019-12-19 | 2020-04-10 | 中国科学院苏州生物医学工程技术研究所 | Hair growth instrument with imaging system |
CN111601459A (en) * | 2020-05-29 | 2020-08-28 | 深圳半岛医疗有限公司 | Hair growing cap, circuit board constructed by hair growing cap and manufacturing method of hair growing cap |
TWI813208B (en) * | 2022-03-16 | 2023-08-21 | 瑞愛生醫股份有限公司 | Wearable laser phototherapy device with safety protection function |
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US20220280809A1 (en) | 2022-09-08 |
CA177607S (en) | 2019-07-03 |
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EP3328492A4 (en) | 2019-06-19 |
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