CN108114322A - A kind of porous tooth implant of surface inserting biodegradable layer and preparation method thereof - Google Patents

A kind of porous tooth implant of surface inserting biodegradable layer and preparation method thereof Download PDF

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Publication number
CN108114322A
CN108114322A CN201711250259.1A CN201711250259A CN108114322A CN 108114322 A CN108114322 A CN 108114322A CN 201711250259 A CN201711250259 A CN 201711250259A CN 108114322 A CN108114322 A CN 108114322A
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CN
China
Prior art keywords
implant
biodegradable layer
thread groove
spherical pore
porous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201711250259.1A
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Chinese (zh)
Inventor
季方秋
张春雨
陈贤帅
王亚玲
颜瑜
冯科瀚
冯伟
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GUANGZHOU JIANCHI BIOTECHNOLOGY Co Ltd
Original Assignee
GUANGZHOU JIANCHI BIOTECHNOLOGY Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GUANGZHOU JIANCHI BIOTECHNOLOGY Co Ltd filed Critical GUANGZHOU JIANCHI BIOTECHNOLOGY Co Ltd
Priority to CN201711250259.1A priority Critical patent/CN108114322A/en
Priority to PCT/CN2018/073414 priority patent/WO2019104852A1/en
Publication of CN108114322A publication Critical patent/CN108114322A/en
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A61L27/06—Titanium or titanium alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/12—Materials or treatment for tissue regeneration for dental implants or prostheses

Abstract

The invention discloses a kind of porous tooth implants of surface inserting biodegradable layer and preparation method thereof.Preparation method includes：(1) implant abutment is printed using pure titanium by SLM technologies, surface is equipped with spherical pore or thread groove；(2) internal thread by way of mechanical processing to implant abutment and hexagon link slot finish；(3) metal magnesium granules of the fusing point less than pure titanium are put into spherical pore or thread groove, irradiating heating magnesium granules using laser makes its temperature moment be increased to fusing point, cause melt that can be attached to rapidly on spherical pore or thread groove and form biodegradable layer, tooth implant is can obtain after implant abutment cooling.Biodegradable layer can cover the rough surface of the pure titanium implant foundation pile of SLM printings well, reduce the processing request of SLM printings；The elasticity modulus of magnesium, yield strength be close to bone tissue simultaneously, the problem of avoiding the occurrence of stress shielding；And magnesium has bioactivity, magnesium ion can promote cells grown.

Description

A kind of porous tooth implant of surface inserting biodegradable layer and preparation method thereof
Technical field
The present invention relates to tooth implantation technology fields.
Background technology
Traditional tooth implant is the pure titanium of solid construction or titanium alloy material, and elasticity modulus, yield strength are much larger than Bone tissue, the problem of easily causing stress shielding, and then the regeneration of bone tissue is influenced, and it is unfavorable for synosteosis, it is final to influence plantation The stability and service life of body.The planting body of existing porous structure is manufactured using 3D printing, is influenced by machining accuracy Easily there is manufacturing deficiency, occur the situation of stress concentration at hole, the tooth implant for ultimately resulting in porous structure is being planted The mechanical strength at initial stage is not up to standard.
The content of the invention
For disadvantage mentioned above, the present invention devises a kind of porous tooth implant of surface inserting biodegradable layer material, leads to Cross filling biodegradable layer made of magnesium in the hole of porous tooth implant so that planting body is solid knot in initial planting Structure ensures that it has enough mechanical strengths.After planting, biodegradable layer will voluntarily degrade, and so as to vacate hole, induce bone group It knits and grows into, final planting body and alveolus ostosis synosteosis.
A kind of preparation method of the porous tooth implant of surface inserting biodegradable layer, comprises the following steps：
(1) implant abutment is printed using pure titanium by SLM technologies, surface is equipped with spherical pore or thread groove；
(2) internal thread by way of mechanical processing to implant abutment and hexagon link slot finish；
(3) metal magnesium granules of the fusing point less than pure titanium are put into spherical pore or thread groove, heating magnesium is irradiated using laser Particle makes its temperature moment be increased to fusing point, cause melt can be attached to rapidly on spherical pore or thread groove formed it is degradable Layer can obtain tooth implant after implant abutment cooling.
The porous tooth implant of the surface inserting biodegradable layer as made from above-mentioned preparation method, including implant abutment, institute Stating has porous structure in implant abutment, the spherical pore or thread groove on implant abutment surface are connected with the porous structure, Biodegradable layer penetrates into filling partially or fully porous structure.
Further, fill spherical pore or the biodegradable layer of thread groove protrudes from implant abutment surface.
The porous tooth implant of surface inserting biodegradable layer disclosed by the invention, the biodegradable layer of surface inserting is metal Magnesium heats fusing by laser and adheres to realize, can cover the rough surface of the pure titanium implant foundation pile of SLM printings well, Reduce the processing request of SLM printings；The elasticity modulus of magnesium, yield strength are close to bone tissue simultaneously, so that porous Dental implantion Body the problem of stress shielding will not occur in initial planting；And magnesium has bioactivity, magnesium ion can promote cells grown, Be conducive to accelerate the process of synosteosis.
Description of the drawings
To describe the technical solutions in the embodiments of the present invention more clearly, make required in being described below to embodiment Attached drawing is briefly described.Obviously, described attached drawing is the part of the embodiment of the present invention rather than all implements Example, those skilled in the art without creative efforts, can also be obtained according to these attached drawings other designs Scheme and attached drawing.
Fig. 1 is the implant abutment schematic diagram of embodiment 1；
Fig. 2 is the structure diagram of the porous tooth implant of the surface inserting biodegradable layer of embodiment 1；
Fig. 3 is the implant abutment schematic diagram of embodiment 2；
Fig. 4 is the structure diagram of the porous tooth implant of the surface inserting biodegradable layer of embodiment 2.
Specific embodiment
The technique effect of the design of the present invention, concrete structure and generation is carried out below with reference to embodiment and attached drawing clear Chu is fully described by, to be completely understood by the purpose of the present invention, feature and effect.Obviously, described embodiment is this hair Bright part of the embodiment rather than whole embodiments, the embodiment of the present invention, those skilled in the art are not paying creation Property work on the premise of the other embodiment that is obtained, belong to the scope of protection of the invention.In addition, what is be previously mentioned in text is all Connection/connection relation not singly refers to component and directly connects, and refer to can be according to specific implementation situation, by adding or reducing connection Auxiliary is connect, to form more preferably coupling structure.Each technical characteristic in the invention, in the premise of not conflicting conflict Under can be with combination of interactions.
Embodiment 1：As illustrated in fig. 1 and 2, a kind of porous tooth implant of surface inserting biodegradable layer, is made by SLM technologies Implant abutment 1 is printed with pure titanium, there is porous structure in the implant abutment 1, surface is equipped with spherical pore a2, plantation The spherical pore a2 on 1 surface of body foundation pile is connected with the porous structure, to the interior spiral shell of implant abutment 1 by way of mechanical processing Line and hexagon link slot are finished, and metal magnesium granules of the fusing point less than pure titanium are put into spherical pore a2, using sharp Light irradiation heating magnesium granules make its temperature moment be increased to fusing point, cause melt that can rapidly be attached on spherical pore a2 and ooze Entering filling, partially or fully porous structure forms biodegradable layer a3, and the biodegradable layer a3 of filling spherical pore a2 cools down processus aboralis for kind 1 surface of implant foundation pile.Stephanoporate implant evenly distributed spherical pore a2, the planting body can ensure the sufficient interference volume of offer, And ensure planting body uniform force.
Embodiment 2：As shown in Figures 3 and 4, it is spherical pore being substituted for thread groove b2 with the distinctive points of embodiment 1.It fills out Interim ridge can be served as by filling the biodegradable layer b3 of thread groove b2 and protrusion, and installation is facilitated to fix.
SLM technologies combine the mode of machining and Laser Processing, shorten the process-cycle of tooth implant, ensure that its is whole Body and structural strength.And this processing method can ignore SLM manufacturing tolerances, reduce cost.That inlays is degradable Layer protrudes from surface, is uniformly distributed, and ensures planting body uniform force, and surgical procedure is convenient, so as to ensure that planting body Primary stability and structural strength.Initial planting high stability and good biocompatibility, biodegradable layer degradation release magnesium from Son promotes the regeneration of osteocyte.Growing into for hole induction osteocyte is vacated simultaneously, finally ensure that the generation of synosteosis.So as to Improve the success rate of implant operation.And the planting body scope of application of the present invention is wider.
The better embodiment of the present invention is illustrated above, but the invention is not limited to the implementation Example, those skilled in the art can also make a variety of equivalent modifications on the premise of without prejudice to spirit of the invention or replace It changes, these equivalent modifications or replacement are all contained in the application claim limited range.

Claims (4)

1. a kind of preparation method of the porous tooth implant of surface inserting biodegradable layer, it is characterised in that comprise the following steps：
(1) implant abutment is printed using pure titanium by SLM technologies, surface is equipped with spherical pore or thread groove；
(2) internal thread by way of mechanical processing to implant abutment and hexagon link slot finish；
(3) metal magnesium granules of the fusing point less than pure titanium are put into spherical pore or thread groove, heating magnesium granules is irradiated using laser Its temperature moment is made to be increased to fusing point, causes melt that can be attached to rapidly on spherical pore or thread groove and forms biodegradable layer, treat Tooth implant is can obtain after implant abutment cooling.
2. a kind of porous tooth implant of the surface inserting biodegradable layer as made from preparation method described in claim 1.
3. porous tooth implant according to claim 2, it is characterised in that：Including implant abutment, the planting body base There is porous structure, the spherical pore or thread groove on implant abutment surface are connected with the porous structure, and biodegradable layer oozes in stake Enter filling partially or fully porous structure.
4. porous tooth implant according to claim 2, it is characterised in that：Fill the biodegradable layer of spherical pore or thread groove Protrude from implant abutment surface.
CN201711250259.1A 2017-12-01 2017-12-01 A kind of porous tooth implant of surface inserting biodegradable layer and preparation method thereof Pending CN108114322A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201711250259.1A CN108114322A (en) 2017-12-01 2017-12-01 A kind of porous tooth implant of surface inserting biodegradable layer and preparation method thereof
PCT/CN2018/073414 WO2019104852A1 (en) 2017-12-01 2018-01-19 Porous dental implant having surface inlaid with degradable layer and preparation method therefor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711250259.1A CN108114322A (en) 2017-12-01 2017-12-01 A kind of porous tooth implant of surface inserting biodegradable layer and preparation method thereof

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Publication Number Publication Date
CN108114322A true CN108114322A (en) 2018-06-05

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019104853A1 (en) * 2017-12-01 2019-06-06 广州市健齿生物科技有限公司 Porous dental implant capable of degrading so as to release magnesium ions
CN110614369A (en) * 2018-06-20 2019-12-27 韩国生产技术研究院 One-step method for producing a laminated porous member
CN110614372A (en) * 2018-06-20 2019-12-27 韩国生产技术研究院 One-step manufacturing method of laminated porous member with curved surface
CN110742705A (en) * 2019-10-28 2020-02-04 西安交通大学 Porous ultrashort implant filled with degradable ceramic and preparation method thereof
WO2021103286A1 (en) * 2019-11-29 2021-06-03 佛山市安齿生物科技有限公司 Method for preparing dental implant blank
US11872105B1 (en) 2022-12-01 2024-01-16 Robert Parker Dental implant device for regeneration of dental pulp and dentin
US11931224B1 (en) 2022-12-19 2024-03-19 Robert Parker Tooth pod

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101352370A (en) * 2007-07-27 2009-01-28 精工爱普生株式会社 Method for maufacturing dental implant and dental implant
KR20090014027A (en) * 2007-08-03 2009-02-06 쿱케앤볼프주식회사 코리아 Members for dental implant and method of fabricating the same, and dental implant comprising the members
CN101495057A (en) * 2006-08-02 2009-07-29 于利奇研究中心有限公司 Implants with porous outer layer, and process for the production thereof
CN102715960A (en) * 2012-06-01 2012-10-10 上海交通大学 Dental implant and preparation method thereof
CN103357063A (en) * 2012-04-10 2013-10-23 中国科学院金属研究所 Metal composite material capable of inducing bone growth and application thereof
CN105603277A (en) * 2015-12-28 2016-05-25 青岛博泰美联化工技术有限公司 Easily-degraded medical magnesium-alloy material and preparation method thereof
CN105662621A (en) * 2016-02-23 2016-06-15 浙江工业大学 Porous dental implant capable of carrying drug sustained release system and manufacturing method thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016176448A1 (en) * 2015-04-29 2016-11-03 DENTSPLY SIRONA, Inc. Method for creating a mineral trioxide aggregate material with improved biological effects
CN205698065U (en) * 2016-02-23 2016-11-23 浙江工业大学 The porous tooth implant of drug-carrying slow-released system
CN106109032A (en) * 2016-06-27 2016-11-16 西北有色金属研究院 A kind of gradient porous structure tooth implant
CN107126281A (en) * 2017-05-17 2017-09-05 上海交通大学 A kind of high intensity Low rigidity porous titanium implant

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101495057A (en) * 2006-08-02 2009-07-29 于利奇研究中心有限公司 Implants with porous outer layer, and process for the production thereof
CN101352370A (en) * 2007-07-27 2009-01-28 精工爱普生株式会社 Method for maufacturing dental implant and dental implant
KR20090014027A (en) * 2007-08-03 2009-02-06 쿱케앤볼프주식회사 코리아 Members for dental implant and method of fabricating the same, and dental implant comprising the members
CN103357063A (en) * 2012-04-10 2013-10-23 中国科学院金属研究所 Metal composite material capable of inducing bone growth and application thereof
CN102715960A (en) * 2012-06-01 2012-10-10 上海交通大学 Dental implant and preparation method thereof
CN105603277A (en) * 2015-12-28 2016-05-25 青岛博泰美联化工技术有限公司 Easily-degraded medical magnesium-alloy material and preparation method thereof
CN105662621A (en) * 2016-02-23 2016-06-15 浙江工业大学 Porous dental implant capable of carrying drug sustained release system and manufacturing method thereof

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019104853A1 (en) * 2017-12-01 2019-06-06 广州市健齿生物科技有限公司 Porous dental implant capable of degrading so as to release magnesium ions
CN110614369A (en) * 2018-06-20 2019-12-27 韩国生产技术研究院 One-step method for producing a laminated porous member
CN110614372A (en) * 2018-06-20 2019-12-27 韩国生产技术研究院 One-step manufacturing method of laminated porous member with curved surface
CN110614372B (en) * 2018-06-20 2021-11-19 韩国生产技术研究院 One-step manufacturing method of laminated porous member with curved surface
CN110742705A (en) * 2019-10-28 2020-02-04 西安交通大学 Porous ultrashort implant filled with degradable ceramic and preparation method thereof
CN110742705B (en) * 2019-10-28 2021-04-13 西安交通大学 Porous ultrashort implant filled with degradable ceramic and preparation method thereof
WO2021103286A1 (en) * 2019-11-29 2021-06-03 佛山市安齿生物科技有限公司 Method for preparing dental implant blank
US11872105B1 (en) 2022-12-01 2024-01-16 Robert Parker Dental implant device for regeneration of dental pulp and dentin
US11931224B1 (en) 2022-12-19 2024-03-19 Robert Parker Tooth pod

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