CN108114129A - 一种用于治疗痛风的丸剂药物及其制备方法 - Google Patents

一种用于治疗痛风的丸剂药物及其制备方法 Download PDF

Info

Publication number
CN108114129A
CN108114129A CN201810045997.0A CN201810045997A CN108114129A CN 108114129 A CN108114129 A CN 108114129A CN 201810045997 A CN201810045997 A CN 201810045997A CN 108114129 A CN108114129 A CN 108114129A
Authority
CN
China
Prior art keywords
chinese
pill medicine
gout
root
desmodium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201810045997.0A
Other languages
English (en)
Inventor
夏瑜
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chengdu Feilong Water Treatment Technology Research Institute Qingbaijiang First Branch
Original Assignee
Chengdu Feilong Water Treatment Technology Research Institute Qingbaijiang First Branch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chengdu Feilong Water Treatment Technology Research Institute Qingbaijiang First Branch filed Critical Chengdu Feilong Water Treatment Technology Research Institute Qingbaijiang First Branch
Priority to CN201810045997.0A priority Critical patent/CN108114129A/zh
Publication of CN108114129A publication Critical patent/CN108114129A/zh
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238—Saposhnikovia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/37—Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/744—Gardenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/756—Phellodendron, e.g. corktree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/86—Violaceae (Violet family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/894—Dioscoreaceae (Yam family)
    • A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

本发明属于中药制剂领域，目的是根据中医治疗痛风的认识机理而提供一种用于治疗痛风的丸剂药物，所述丸剂药物的各个组分及其质量份比如下：黄茋100～350g、苍术30～100g、防风50～120g、黄柏80～160g、牛膝50～160g、茵陈60～160g、栀子60～120g、地丁250～560g、天葵150～260g、桃仁80～160g、川芎50～120g、萆薢50～150g、当归60～150g、牛蒡子50～100g、海风藤60～150g、独一味30～70g、地骨皮60～150g、延胡索30～100g、雷公藤90～130g、金钱草150～650g；本发明提供的药物是一个很好的中药组方。

Description

一种用于治疗痛风的丸剂药物及其制备方法
技术领域
本发明属于中药制剂领域，具体涉及一种用于治疗痛风的丸剂药物，特别是供痛风患者使用的丸剂药物及其制备方法的领域。
背景技术
医者认为，痛风是嘌呤代谢异常致使尿酸合成增加而导致的代谢性疾病。肾功能异常时，由于肾脏的尿酸清除率下降也会引起尿酸水平上升。血浆中的尿酸达到饱和，导致尿酸单钠结晶沉积在远端关节周围相对缺乏血管的组织中。这种结晶的出现可导致单关节或者多关节的急性炎性滑膜炎，痛风在男性中较为多见，拇趾是最常见的受累区域，50％～70％的初次发病就在于此。90％的痛风患者在其一生中的某个时期会发生第一跖趾关节受累。其他可能受累的足部区域有足背部、足跟以及踝部。除了累及关节之外，尿酸结晶还可以沉积在皮下，被称作痛风结节。
就目前而言，痛风尚无根治的方法，临床上多用甾体类抗炎药、糖皮质激素、别嘌呤醇、秋水仙碱等，这类药品能迅速缓解疼痛。但也存在一定的缺陷，治标不治本，副作用大，长期服用，还对人体的胃肠道、肝肾功能有较大的损害。
那么，就如何找到一种可有效治疗痛风的中药组合物，是本领域技术人员亟待要解决的问题。
发明内容
随着我国中医中药学的不断发展，在治疗痛风上，人们逐渐意识到了中医治疗痛风的优点，且在治疗过程中疗效好、见效快、毒副作用小等优势，针对现有西医治疗痛风的现状，本发明的目的是在于提供一种用于治疗痛风的丸剂药物，以解决痛风患者早日恢复健康的问题。该药物是以常见的中药为原料，通过选择合理的药物及质量份比，可有效治疗上述痛风。
为达到上述发明的目的，本发明所采用的技术方案为：提供一种用于治疗痛风的丸剂药物及其制备方法，其特征在于，所述丸剂药物的各个组分及质量份比如下所示：
黄茋100～350g、苍术30～100g、防风50～120g、黄柏80～160g、牛膝50～160g、茵陈60～160g、栀子60～120g、地丁250～560g、天葵150～260g、桃仁80～160g、川芎50～120g、萆薢50～150g、当归60～150g、牛蒡子50～100g、海风藤60～150g、独一味30～70g、地骨皮60～150g、延胡索30～100g、雷公藤90～130g、金钱草150～650g，辅料：淀粉适量。
一种用于治疗痛风的丸剂药物及其制备方法，其特征在于，所述丸剂药物的各个组分及质量份比如下所示：
黄茋115～310g、苍术36～90g、防风56～105g、黄柏90～140g、牛膝56～140g、茵陈70～140g、栀子70～105g、地丁280～500g、天葵180～230g、桃仁90～140g、川芎56～105g、萆薢56～130g、当归70～130g、牛蒡子56～90g、海风藤70～130g、独一味36～60g、地骨皮70～130g、延胡索36～90g、雷公藤100～115g、金钱草180～560g，辅料：淀粉适量。
一种用于治疗痛风的丸剂药物及其制备方法，其特征在于，所述丸剂药物的各个组分及质量份比如下所示：
黄茋280g、苍术80g、防风95g、黄柏120g、牛膝120g、茵陈120g、栀子95g、地丁430g、天葵200g、桃仁120g、川芎95g、萆薢118g、当归118g、牛蒡子80g、海风藤118g、独一味52g、地骨皮118g、延胡索80g、雷公藤110g、金钱草500g，辅料：淀粉适量。
一种用于治疗痛风的丸剂药物及其制备方法，其特征在于，所述方法包括如下步骤制备而成：
A、除淀粉外，将上述原料中药拣去杂质、粉尘及其干燥后，按照质量份比共研为极细末待用；
B、按照传统制备中药水丸剂的方法，将研磨好的极细末药物和淀粉过筛后，放入药器中混合拌均，然后制备成水丸剂（其水丸的粒度为：3.9mm～4.0mm），进而烘干、消毒，分装密封即得。
一种用于治疗痛风的丸剂药物及其制备方法，其特征在于，所述服用方法为：将制备好的水丸剂药物以每日三次服用，早中晚各服一次，给药量6.5g/次，饭后半小时温开水送服。（忌烟、酒、生葱、生蒜、辛辣刺激性食物）。26天为一个疗程，治疗3～6个疗程后，检查：血尿酸降至正常范围，临床症状及体征消失，病获临时痊愈。
本发明组方中的各原料中药在中国药典、中国辞典以及其中华本草中均有详细的记载。本发明选用其中最常见的中药为原料，充分发挥各组分的药理功效：
黄茋，性味：甘、微温，具有补气固表、利尿托毒、排脓、敛疮生肌之功效，用于治疗气虚乏力、食少便溏、中气下陷、久泻脱肛、便血崩漏、表虚自汗、气虚水肿、痈疽难溃、久溃不敛、血虚痿黄、内热消渴、慢性肾炎蛋白尿、糖尿病等症；
苍术，性味：辛、苦、温，具有燥湿健脾、去风湿之功效，用于治疗脾为湿困引起的运化失调、食欲不振、呕恶烦闷、腹胀泄泻、关节肢体疼痛；
防风，性味：味辛、甘、性微温，具有祛风解表、胜湿止痛、止痉定搐之功效，用于治疗外感表证、风疹瘙痒、风湿痹痛、破伤风等症；
黄柏，性味：苦、寒，具有清热燥湿、泻火解毒、除骨蒸清虚热之功效，用于治疗湿热泻痢、黄疸、带下、热淋、脚气、痿辟、骨蒸劳热、盗汗、遗精、疮疡肿毒、湿疹瘙痒；
牛膝，性味：苦、酸、性平，具有补肝肾、强筋骨、活血通经、引敌国(火)下行、利尿通淋之功效，用于治疗腰膝酸痛、下肢痿软、血滞经闭、痛经、产后血瘀腹痛、徵瘕、胞衣不下、热淋、血淋、跌打损伤、痈肿恶疮、咽喉肿痛，还用于腰膝酸痛、筋骨无力、经闭癥瘕、肝阳眩晕；
茵陈，性味：味苦、辛、性微寒，具有清利湿热、利胆退黄之功效，用于治疗黄疸尿少、湿温暑湿、湿疮瘙痒；
栀子，性味：苦、寒，具有泻火除烦、清热利湿、凉血解毒、外用消肿止痛之功效，用于治疗热病心烦、湿热黄疸、淋证涩痛、血热吐衄、目赤肿痛、火毒疮疡，外治扭挫伤痛；
地丁，性味：苦、寒，具有清热利湿、解毒消肿之功效，用于治疗疔疮、痈肿、瘰疬、黄疸、痢疾、腹泻、目赤、喉痹、毒蛇咬伤等病症；
天葵，性味：甘苦、寒，具有清热、解毒、消肿、散结、利尿之功效，用于治疗痈肿、瘰疬、疔疮、淋浊、带下、肺虚咳嗽、疝气、癫痫、小儿惊风、痔疮、跌打损伤、毒蛇咬伤；
桃仁，性味：苦甘、平，无毒，具有破血行瘀、润燥滑肠之功效，用于治疗经闭、癥瘕、热病蓄血、风痹、疟疾、跌打损伤、瘀血肿痛、血燥便秘；
川芎，性味：辛、温，具有行气开郁、法风燥湿、活血止痛之功效，用于治疗风冷头痛旋晕、胁痛腹疼、寒痹筋挛、经闭、难产、产后瘀阻块痛、痈疽疮疡、月经不调、瘕腹痛、胸胁刺痛、跌扑肿痛、风湿痹痛；
萆薢，性味：苦甘、平，具有利湿去浊、祛风除痹之功效，用于治疗淋浊白带、腰膝痹痛、湿热疮毒；
当归，性味：味甘、辛、苦、性温，具有补血、活血、调经止痛、润燥滑肠之功效，用于治疗血虚诸证、月经不调、经闭、痛经、癥瘕结聚、崩漏、虚寒腹痛、痿痹、肌肤麻木、肠燥便难、赤痢后重、痈疽疮疡、跌扑损伤；
牛蒡子，性味：味辛、苦、性寒，具有疏散风热、宣肺透疹、解毒利咽之功效，用于治疗风热感冒、咳嗽痰多、麻疹、风疹、荨麻疹、疹出不畅、咽喉肿痛、痄腮、流行性腮腺炎、丹毒、痈肿疮毒；
海风藤，性味：味辛、苦、性微温，具有祛风湿、通经络、止痹痛之功效，用于治疗风寒湿痹、肢节疼痛、筋脉拘挛、屈伸不利；
独一味，性味：味甘、苦、性平，具有活血止血、祛风止痛之功效，用于治疗跌打损伤、外伤出血、风湿痹痛、黄水病等症；
地骨皮，性味：甘、寒，具有清热凉血、退骨蒸潮热之功效，用于治疗骨蒸劳热、肺热咳嗽、血热出血症；
延胡索，性味：辛、苦、温，具有活血、利气、止痛之功效，用于治疗胸胁、脘腹疼痛、经闭痛经、产后瘀阻、跌扑肿痛；
雷公藤，性味：味苦、辛、性凉，大毒，具有祛风除湿、活血通络、消肿止痛、杀虫解毒之功效，用于治疗类风湿性关节炎、风湿性关节炎、肾小球肾炎、肾病综合征、红斑狼疮、口眼干燥综合征、白塞病、湿疹、银屑病、麻风病、疥疮、顽癣等症；
金钱草，性味：甘、咸、微寒，具有清利湿热、通淋、消肿之功效，用于治疗热淋、沙淋、尿涩作痛、黄疸尿赤、痈肿疔疮、毒蛇咬伤、肝胆结石、尿路结石。
本发明药物是基于中医治疗痛风的原则，从依据痛风的病理机制及药理作用认为：就痛风，本发明所提供的药物中的各原料中药药效共奏，对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述痛风的治疗而提出的一种中药配方，采用该配方制备的药物药效好，见效快，是一个很好的中药组方，特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述：
实施例1：
一种用于治疗痛风的丸剂药物，其特征在于，所述丸剂药物的各个组分及质量份比如下所示：
黄茋280g、苍术80g、防风95g、黄柏120g、牛膝120g、茵陈120g、栀子95g、地丁430g、天葵200g、桃仁120g、川芎95g、萆薢118g、当归118g、牛蒡子80g、海风藤118g、独一味52g、地骨皮118g、延胡索80g、雷公藤110g、金钱草500g，辅料：淀粉适量。
实施例2：
一种用于治疗痛风的丸剂药物，其特征在于，所述丸剂药物的各个组分及质量份比如下所示：
黄茋310g、苍术90g、防风105g、黄柏140g、牛膝140g、茵陈140g、栀子105g、地丁500g、天葵230g、桃仁140g、川芎105g、萆薢130g、当归130g、牛蒡子90g、海风藤130g、独一味60g、地骨皮130g、延胡索90g、雷公藤115g、金钱草560g，辅料：淀粉适量。
实施例3：
一种用于治疗痛风的丸剂药物，其特征在于，所述丸剂药物的各个组分及质量份比如下所示：
黄茋350g、苍术100g、防风120g、黄柏160g、牛膝160g、茵陈160g、栀子120g、地丁560g、天葵260g、桃仁160g、川芎120g、萆薢150g、当归150g、牛蒡子100g、海风藤150g、独一味70g、地骨皮150g、延胡索100g、雷公藤130g、金钱草650g，辅料：淀粉适量。
典型病例：
经临床诊断治疗痛风患者共1595例，年龄为56岁以上的990例，只有605例为56岁以下。1595例患者中症状及体征消失的有1005例，有效的510例，无效的80例。总有效率达95%。

Claims (3)

1.一种用于治疗痛风的丸剂药物，其特征在于，所述丸剂药物的各个组分及质量份比如下所示：
黄茋100～350g、苍术30～100g、防风50～120g、黄柏80～160g、牛膝50～160g、茵陈60～160g、栀子60～120g、地丁250～560g、天葵150～260g、桃仁80～160g、川芎50～120g、萆薢50～150g、当归60～150g、牛蒡子50～100g、海风藤60～150g、独一味30～70g、地骨皮60～150g、延胡索30～100g、雷公藤90～130g、金钱草150～650g，辅料：淀粉适量。
2.根据权利要求1所述的用于治疗痛风的丸剂药物，其特征在于，所述丸剂药物的各个组分及质量份比如下所示：
黄茋115～310g、苍术36～90g、防风56～105g、黄柏90～140g、牛膝56～140g、茵陈70～140g、栀子70～105g、地丁280～500g、天葵180～230g、桃仁90～140g、川芎56～105g、萆薢56～130g、当归70～130g、牛蒡子56～90g、海风藤70～130g、独一味36～60g、地骨皮70～130g、延胡索36～90g、雷公藤100～115g、金钱草180～560g，辅料：淀粉适量。
3.根据权利要求1至2所述的用于治疗痛风的丸剂药物，其特征在于，所述丸剂药物的各个组分及质量份比如下所示：
黄茋280g、苍术80g、防风95g、黄柏120g、牛膝120g、茵陈120g、栀子95g、地丁430g、天葵200g、桃仁120g、川芎95g、萆薢118g、当归118g、牛蒡子80g、海风藤118g、独一味52g、地骨皮118g、延胡索80g、雷公藤110g、金钱草500g，辅料：淀粉适量。
CN201810045997.0A 2018-01-17 2018-01-17 一种用于治疗痛风的丸剂药物及其制备方法 Withdrawn CN108114129A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810045997.0A CN108114129A (zh) 2018-01-17 2018-01-17 一种用于治疗痛风的丸剂药物及其制备方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810045997.0A CN108114129A (zh) 2018-01-17 2018-01-17 一种用于治疗痛风的丸剂药物及其制备方法

Publications (1)

Publication Number Publication Date
CN108114129A true CN108114129A (zh) 2018-06-05

Family

ID=62233956

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810045997.0A Withdrawn CN108114129A (zh) 2018-01-17 2018-01-17 一种用于治疗痛风的丸剂药物及其制备方法

Country Status (1)

Country Link
CN (1) CN108114129A (zh)

Similar Documents

Publication Publication Date Title
CN107441372A (zh) 一种治疗糖尿病的丸剂药物及其制备方法
CN107537015A (zh) 一种治疗风湿寒热所致痹病的丸剂药物及制备方法
CN108159176A (zh) 一种治疗退行性骨关节病的丸剂药物及其制备方法
CN106729429A (zh) 一种活血化瘀的中药组合物及其制备方法
CN106267098A (zh) 一种可有效治疗痛风的中药组合物及其制备方法
CN108114129A (zh) 一种用于治疗痛风的丸剂药物及其制备方法
CN101797291B (zh) 治疗骨质增生的中药药物
CN107582964A (zh) 一种可有效治疗类风湿关节炎的丸剂药物及制备方法
CN107582794A (zh) 一种可有效治疗痛风病的丸剂药物及其制备方法
CN108159231A (zh) 一种治疗痛风的丸剂药物及其制备方法
CN107638465A (zh) 一种治疗关节疼痛的中药组合物及其制备方法
CN107335021A (zh) 一种治疗黄疸型肝炎的丸剂药物及制备方法
CN107596189A (zh) 一种治疗痛风和关节炎的胶囊剂药物及其制备方法
CN108143981A (zh) 一种用于治疗痛风的丸剂药物及制备方法
CN108096517A (zh) 一种治疗痛风的新型中药组合物及制备方法
CN107397833A (zh) 一种可有效治疗骨病的中药组合物及制备方法
CN108096338A (zh) 一种治疗痛风的中药组合物丸剂及制备方法
CN107519457A (zh) 一种可有效治疗关节炎的内服药物及其制备方法
CN107519369A (zh) 一种用于治疗骨关节炎的丸剂药物及其制备方法
CN107551223A (zh) 一种治疗老年肺气肿的中药组合物及制备方法
CN107412638A (zh) 一种治疗风湿热痹的中药组合物及其制备方法
CN107343948A (zh) 一种可有效治疗乙型肝炎的丸剂药物及其制备方法
CN107397861A (zh) 一种用于治疗腰椎间盘突出的中药组合物及制备方法
CN107982499A (zh) 一种用于治疗痛风的中药组合物及制备方法
CN108785607A (zh) 一种治疗类风湿关节炎的药物及其制备方法

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication

Application publication date: 20180605

WW01 Invention patent application withdrawn after publication