CN108113909A - Composition based on red autumnal leaves algae extract and preparation method thereof - Google Patents

Composition based on red autumnal leaves algae extract and preparation method thereof Download PDF

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Publication number
CN108113909A
CN108113909A CN201810107585.5A CN201810107585A CN108113909A CN 108113909 A CN108113909 A CN 108113909A CN 201810107585 A CN201810107585 A CN 201810107585A CN 108113909 A CN108113909 A CN 108113909A
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Prior art keywords
parts
composition
autumnal leaves
red autumnal
algae extract
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CN201810107585.5A
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Chinese (zh)
Inventor
葛啸虎
陈海佳
王飞
王一飞
王小燕
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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Priority to CN201810107585.5A priority Critical patent/CN108113909A/en
Publication of CN108113909A publication Critical patent/CN108113909A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/496Triazoles or their condensed derivatives, e.g. benzotriazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4966Triazines or their condensed derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/004Aftersun preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Composition based on a kind of algae extract by red autumnal leaves and preparation method thereof, wherein composition include first composition, second composition and the 3rd ingredient;First composition includes:Double ethylhexylphenol methylamino benzene piperazines, octyl methoxycinnamate, sucrose fatty ester, cetostearyl alcohol, hexadecanol and isobutyl palmitate;Second composition includes:Di-2-ethylhexylphosphine oxide benzotriazole base tetramethyl butyl phenol, xanthans, nano-titanium dioxide, mannitol, hydroxyethyl cellulose and deionized water;3rd ingredient includes following component:Red autumnal leaves algae extract, fibroblast growth factor and sterile water.It is above-mentioned with composition, preferable moistening effect can be played, additionally it is possible to play preferable sun-proof result, it is preferable to the shield effectiveness of the ultraviolet light of 280nm~400nm wavelength.In addition, it can also alleviate the problem of blackening that skin occurs because of being exposed to the sun, there is certain repair to the skin of sunburn.

Description

Composition based on red autumnal leaves algae extract and preparation method thereof
Technical field
The present invention relates to daily technical field, more particularly to the composition based on a kind of algae extract by red autumnal leaves and its Preparation method.
Background technology
With the continuous improvement of people's living standards, the skin care idea of people is also constantly enhancing.Especially ultraviolet light pair The injury of skin, also has attracted increasing attention.Correlative study shows that skin is chronically exposed in the ultraviolet light in sunlight Afterwards, the aging of skin can be accelerated, also easily so that skin damages.Although many people can not discover in the short time, need not Doubt, can accelerate dermopathic risk occur or even have the risk for inducing cutaneum carcinoma.
Contain floridosides in red autumnal leaves algae (DELESSERIA SANGUINEA), with preferable moistening effect, have latent Power is applied in cosmetics.Floridosides also has the effects that anti-oxidant, anti-inflammatory, immunological regulation.In addition, floridosides is to biology The inhibitory action that body melanin generates.Therefore, it is necessary to a kind of being extracted with red autumnal leaves algae based on developing algae extract by red autumnal leaves Composition based on object and preparation method thereof.
The content of the invention
Based on this, it is necessary to composition based on providing a kind of algae extract by red autumnal leaves and preparation method thereof.
Composition based on a kind of algae extract by red autumnal leaves, including first composition, second composition and the 3rd ingredient;
The first composition includes each component of following mass parts:Double-ethylhexylphenol methylamino benzene piperazine 11 parts~14 Part, 4 parts~6 parts of octyl methoxycinnamate, 4.5 parts~4.9 parts of sucrose fatty ester, 1.5 parts~2.1 parts of cetostearyl alcohol, 8.5 parts~10 parts of 1.1 parts~1.25 parts of hexadecanol and isobutyl palmitate;
The second composition includes each component of following mass parts:Methylene bis-benzotriazolyl tetramethyl butyl phenol 7.5 Part~8.5 parts, 0.15 part~0.25 part of xanthans, 2.5 parts~3.1 parts of nano-titanium dioxide, 2 parts~2.5 parts of mannitol, hydroxyl second 34 parts~35 parts of 0.1 part~0.12 part of base cellulose and deionized water;
3rd ingredient includes each component of following mass parts:70 parts~85 parts of red autumnal leaves algae extract, fibroblast 80 parts~85 parts of 0.00015 part~0.00032 part of growth factor and sterile water;
Wherein, the first composition, the second composition and the ternary mass ratio are 1:1:" 0.2~ 0.25”。
It should be noted that composition also can be regarded as sunscreen.In other words, composition is sunscreen.
In one of the embodiments, the 3rd ingredient further includes 5 parts~9 parts of epidermal stem cells active ingredient.
In one of the embodiments, the fibroblast growth factor for recombination human basic fibroblast growth because Son.
In one of the embodiments, the first composition, the second composition and the ternary mass ratio are 1:1:" 0.22~0.24 ".
In one of the embodiments, the first composition, the second composition and the ternary mass ratio are 1:1:0.23.
The preparation method of composition based on a kind of algae extract by red autumnal leaves, based on the algae extract by red autumnal leaves Composition is the as above composition based on red autumnal leaves algae extract described in any embodiment, and the preparation method is included such as Lower step:
80 degrees Celsius~84 degrees Celsius are heated to after each component in the first composition is mixed, obtains the first product;
It is heated to seething with excitement after each component of the second composition is mixed, and is obtained after being cooled to 80 degrees Celsius~84 degrees Celsius To the second product;
Second product is added in the first product and is uniformly mixed, and is obtained after being cooled to 43 degrees Celsius~46 degrees Celsius To third product;
It is added in third product and is uniformly mixed after ternary each component is mixed, obtain the 4th product;
4th product is cooled to after room temperature to get to the composition based on the algae extract by red autumnal leaves.
In one of the embodiments, after each component in the first composition is mixed 80 degrees Celsius~82 are heated to take the photograph Family name's degree obtains first product.
In one of the embodiments, 81.5 degrees Celsius are heated to after each component in the first composition is mixed, is obtained To first product.
In one of the embodiments, second product is added in the first product and be uniformly mixed, and be cooled to The third product is obtained after 44.5 degrees Celsius.
Composition based on the above-mentioned algae extract by red autumnal leaves, by being prepared based on red autumnal leaves algae extract, energy Enough play preferable moistening effect;By with double-ethylhexylphenol methylamino benzene piperazine and di-2-ethylhexylphosphine oxide-benzotriazole base tetramethyl Base butylphenol is basic substance having sun-screening function, and double-ethylhexylphenol methylamino benzene piperazine nearby has maximum absorption band at 342 nanometers, But it is poor to the absorption after 370 nanometers, and methylene bis-benzotriazolyl tetramethyl butyl phenol can with sorption enhanced ultraviolet light, There is certain reflection and scatters ultraviolet simultaneously, especially in methylene bis-benzotriazolyl tetramethyl butyl phenol 7.5 parts~8.5 parts when being used in conjunction with double -11 parts~14 parts of ethylhexylphenol methylamino benzene piperazine, di-2-ethylhexylphosphine oxide-benzotriazole Base tetramethyl butyl phenol can make up double-ethylhexylphenol methylamino benzene piperazine to wavelength in 370 nanometers or more of ultraviolet light The problem of poor is absorbed, so that the sun-proof result of the composition based on red autumnal leaves algae extract is more preferably.In addition, red autumnal leaves algae Floridosides in extract is on the basis of moisturizing, with methylene bis-benzotriazolyl tetramethyl butyl phenol 7.5 parts~8.5 When part and common double -11 parts~14 parts of ethylhexylphenol methylamino benzene piperazine, di-2-ethylhexylphosphine oxide-benzotriazole base tetramethyl is enabled to The time lengthening of the sun-proof result of base butylphenol and double-ethylhexylphenol methylamino benzene piperazine.Also, in red autumnal leaves algae extract Floridosides has melanin certain inhibitory action, the problem of can alleviating the blackening that skin occurs because of being exposed to the sun, red When 0.00015 part~0.00032 part of 70 parts~85 parts of leaf algae extract and fibroblast growth factor are common, additionally it is possible to shining The skin of wound has certain repair.Composition based on the above-mentioned algae extract by red autumnal leaves, can play preferable guarantor Wet effect, additionally it is possible to preferable sun-proof result is played, it is preferable to the shield effectiveness of the ultraviolet light of 280nm~400nm wavelength.This Outside, the problem of blackening that skin occurs because of being exposed to the sun can also be alleviated, there is certain repair to the skin of sunburn. Also, its also have preferable radical scavenging activity, can the free chain reaction caused by ultraviolet light play further Suspension effect, so as to be further reduced injury of the ultraviolet light to skin.
Description of the drawings
The step of Fig. 1 is the preparation method of the red autumnal leaves algae extract of one embodiment of the invention is schemed.
The step of Fig. 2 is the preparation method of the composition based on red autumnal leaves algae extract of one embodiment of the invention is schemed.
Specific embodiment
For the ease of understanding the present invention, the present invention is described more fully below with reference to relevant drawings.In attached drawing Give the better embodiment of the present invention.But the present invention can realize in many different forms, however it is not limited to herein Described embodiment.On the contrary, the purpose of providing these embodiments is that make to understand more the disclosure Add thorough and comprehensive.Certainly, they are merely examples, and is not intended to limit the present invention.In addition, the present invention can be in difference Repeat reference numerals and/or letter in example.This repetition is for purposes of simplicity and clarity, itself not indicate to be discussed Relation between various embodiments and/or setting.It should be noted that when element is referred to as " being fixed on " another element, it It can be directly on another element or there may also be elements placed in the middle.When an element be considered as " connection " another Element, it can be directly to another element or may be simultaneously present centering elements.Term as used herein " is hung down It is straight ", " horizontal ", "left", "right" and similar statement for illustrative purposes only, be not offered as being uniquely to implement Mode.In the description of the present invention, it is necessary to which explanation, unless otherwise prescribed and limits, term " installation ", " connected ", " company Connect " it should be interpreted broadly, for example, it may be the connection inside mechanical connection or electrical connection or two elements, Ke Yishi It is connected directly, can also be indirectly connected by intermediary, it for the ordinary skill in the art, can be according to specific Situation understands the concrete meaning of above-mentioned term.In addition, term " first ", " second " be only used for description purpose, and it is not intended that Indicate or imply relative importance or the implicit quantity for indicating indicated technical characteristic." first ", " are defined as a result, At least one this feature can be expressed or be implicitly included to two " feature.In the description of invention, " multiple " be meant that It is two few, such as two, three etc., unless otherwise specifically defined.In the description of the present invention, " several " are meant that It is at least one, such as one, two etc., unless otherwise specifically defined.Unless otherwise defined, it is used herein all Technical and scientific term have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs.Made herein Term is intended merely to the purpose of description specific embodiment, it is not intended that in the limitation present invention.Art used herein Language " and/or " include the arbitrary and all combinations of one or more relevant Listed Items.
For example, the composition based on a kind of algae extract by red autumnal leaves, including first composition, second composition and the three one-tenth Point;The first composition, the second composition and the ternary mass ratio are 1:1:" 0.2~0.25 ".Wherein:
The first composition includes each component of following mass parts:Double-ethylhexylphenol methylamino benzene piperazine 11 parts~14 Part, 4 parts~6 parts of octyl methoxycinnamate, 4.5 parts~4.9 parts of sucrose fatty ester, 1.5 parts~2.1 parts of cetostearyl alcohol, 8.5 parts~10 parts of 1.1 parts~1.25 parts of hexadecanol and isobutyl palmitate;
The second composition includes each component of following mass parts:Methylene bis-benzotriazolyl tetramethyl butyl phenol 7.5 Part~8.5 parts, 0.15 part~0.25 part of xanthans, 2.5 parts~3.1 parts of nano-titanium dioxide, 2 parts~2.5 parts of mannitol, hydroxyl second 34 parts~35 parts of 0.1 part~0.12 part of base cellulose and deionized water;
3rd ingredient includes each component of following mass parts:70 parts~85 parts of red autumnal leaves algae extract, fibroblast 80 parts~85 parts of 0.00015 part~0.00032 part of growth factor and sterile water.
It should be noted that composition also can be regarded as sunscreen.In other words, composition is sunscreen.
Composition based on the above-mentioned algae extract by red autumnal leaves, by being prepared based on red autumnal leaves algae extract, energy Enough play preferable moistening effect;By with double-ethylhexylphenol methylamino benzene piperazine and di-2-ethylhexylphosphine oxide-benzotriazole base tetramethyl Base butylphenol is basic substance having sun-screening function, and double-ethylhexylphenol methylamino benzene piperazine nearby has maximum absorption band at 342 nanometers, But it is poor to the absorption after 370 nanometers, and methylene bis-benzotriazolyl tetramethyl butyl phenol can with sorption enhanced ultraviolet light, There is certain reflection and scatters ultraviolet simultaneously, especially in methylene bis-benzotriazolyl tetramethyl butyl phenol 7.5 parts~8.5 parts when being used in conjunction with double -11 parts~14 parts of ethylhexylphenol methylamino benzene piperazine, di-2-ethylhexylphosphine oxide-benzotriazole Base tetramethyl butyl phenol can make up double-ethylhexylphenol methylamino benzene piperazine to wavelength in 370 nanometers or more of ultraviolet light The problem of poor is absorbed, so that the sun-proof result of the composition based on red autumnal leaves algae extract is more preferably.In addition, red autumnal leaves algae Floridosides in extract is on the basis of moisturizing, with methylene bis-benzotriazolyl tetramethyl butyl phenol 7.5 parts~8.5 When part and double -11 parts~14 parts of ethylhexylphenol methylamino benzene piperazine are used in conjunction with, di-2-ethylhexylphosphine oxide-benzotriazole base is enabled to The time lengthening of the sun-proof result of tetramethyl butyl phenol and double-ethylhexylphenol methylamino benzene piperazine.By adding in nano-silica Change titanium, medium wave (280nm~320nm) have preferable shielding action, especially 2.5 parts~3.1 parts of nano-titanium dioxide, 7.5 parts of double -11 parts~14 parts of ethylhexylphenol methylamino benzene piperazine and methylene bis-benzotriazolyl tetramethyl butyl phenol~ 8.5 parts when being used together so that sun-proof result is more preferable, preferable to the shield effectiveness of the ultraviolet light of 280nm~400nm wavelength. Also, the floridosides in red autumnal leaves algae extract has certain inhibitory action to melanin, can alleviate skin because being exposed to the sun And 0.00015 part of the problem of blackening of appearance, 70 parts~85 parts of red autumnal leaves algae extract and fibroblast growth factor~ 0.00032 part it is common when, additionally it is possible to there is certain repair to the skin of sunburn.Especially needed further explanation, Floridosides in red autumnal leaves algae extract also has the function of certain anti-oxidant and homeo-osmosis, and ultraviolet light can be caused Free chain reaction play the role of certain suspension, so as to be further reduced injury of the ultraviolet light to skin.Especially Be red autumnal leaves algae extract when mannitol is used together, radical scavenging activity is further enhanced, can be to ultraviolet light Caused by free chain reaction play the role of further suspension, so as to be further reduced wound of the ultraviolet light to skin Evil.Certainly, nano-titanium dioxide can also be substituted with titanium dioxide.
Composition based on the above-mentioned algae extract by red autumnal leaves, can play preferable moistening effect, additionally it is possible to play compared with Good sun-proof result, it is preferable to the shield effectiveness of the ultraviolet light of 280nm~400nm wavelength.In addition, it can also alleviate skin The problem of blackening occurred because of being exposed to the sun, has certain repair to the skin of sunburn.Also, it also has preferable Radical scavenging activity, can the free chain reaction caused by ultraviolet light play the role of further suspension, so as to It is further reduced injury of the ultraviolet light to skin.
For example, double-ethylhexylphenol methylamino benzene piperazine is purchased from BASF (Germany, BASF SE), trade name Tinosorb S.For another example, methylene bis-benzotriazolyl tetramethyl butyl phenol is purchased from BASF (Germany, BASF SE), business The name of an article is Tinosorb M.It should be noted that in cetostearyl alcohol, C16:C18=3:7, the i.e. body of hexadecanol and octadecyl alcolol Product is than being 3:7.For another example, cetostearyl alcohol is purchased from the happy Industrial Co., Ltd.s of Shanghai Jin Jin.
In one embodiment, the fibroblast growth factor is recombination human basic fibroblast growth factor.It is in this way, different Source property is smaller, and use is safer, can have better repairing effect and inhibition to the skin of sunburn.
In one embodiment, the first composition, the second composition and the ternary mass ratio are 1:1:“0.22 ~0.24 ".For another example, the first composition, the second composition and the ternary mass ratio are 1:1:0.23.In this way, Better moistening effect can be played, additionally it is possible to preferable sun-proof result is played, to the ultraviolet light of 280nm~400nm wavelength Shield effectiveness it is preferable.In addition, it can also alleviate the problem of blackening that skin occurs because of being exposed to the sun, have to the skin of sunburn There is certain repair.Also, its also have preferable radical scavenging activity, can caused by ultraviolet light free radical chain Further suspension is played the role of in formula reaction, so as to be further reduced injury of the ultraviolet light to skin.
In one embodiment, the first composition includes each component of following mass parts:Double-ethylhexylphenol methylamino benzene 13.5 parts of piperazine, 4.5 parts of octyl methoxycinnamate, 4.7 parts of sucrose fatty ester, 1.9 parts of cetostearyl alcohol, 1.18 parts of hexadecanol And 8.7 parts of isobutyl palmitate;For another example, the second composition includes each component of following mass parts:Di-2-ethylhexylphosphine oxide-benzotriazole 7.8 parts of base tetramethyl butyl phenol, 0.22 part of xanthans, 2.8 parts of nano-titanium dioxide, 2.3 parts of mannitol, hydroxyethyl cellulose 0.11 part and 34.9 parts of deionized water;For another example, the 3rd ingredient includes each component of following mass parts:Red autumnal leaves algae extract 84 parts of 77.5 parts, 0.00029 part of fibroblast growth factor and sterile water.It so, it is possible to play better moistening effect, Preferable sun-proof result can also be played, it is preferable to the shield effectiveness of the ultraviolet light of 280nm~400nm wavelength.In addition, it is also The problem of blackening that skin occurs because of being exposed to the sun can be alleviated, has certain repair to the skin of sunburn.Also, its Also there is preferable radical scavenging activity, can the free chain reaction caused by ultraviolet light play and further stop to make With so as to be further reduced injury of the ultraviolet light to skin.
In one embodiment, the 3rd ingredient further includes 5 parts~9 parts of epidermal stem cells active ingredient.It so, it is possible to damage The cell of wound plays further repair, can enhance the cell metabolism function of Skin Cell especially epidermal cell, increases Strong cutaneous immunisation power, reduces the appearance of erythema etc., also has anti-aging and other effects.Especially epidermal stem cells active ingredient with When red autumnal leaves algae extract and fibroblast growth factor are used in conjunction with, there is synergistic effect to the reparation of skin, it can be into one Cutaneous immunisation power is walked, inhibitory action is played to the inflammation of skin to a certain extent, additionally it is possible to reduce the appearance of erythema etc..It is preferred that , the mass parts of epidermal stem cells active ingredient are 7.8 parts~9 parts, it is furthermore preferred that the mass parts of epidermal stem cells active ingredient For 8.5 part, further cutaneous immunisation power is so, it is possible, inhibitory action is played to the inflammation of skin to a certain extent, additionally it is possible to Reduce the appearance of erythema etc..
In one embodiment, the 3rd ingredient further includes 1.1 parts~1.77 parts of Pimenta racemosa leaf oil, hydrolyzed wheat protein 0.4 part~0.9 part and 0.6 part~1.05 parts of olibanum resin extract;By adding in many fragrant ((PIMENTA the ACRIS)) trees of spiceleaf 1.1 parts~1.77 parts of leaf oil, can play preferable flavouring effect, simultaneously, additionally it is possible to play inhibitory action for some viruses. By adding in 0.4 part~0.9 part of hydrolyzed wheat protein, hydrolyzed wheat protein contains abundant cystine, has preferable moisturizing And antioxidant effect, additionally it is possible to which softness refinement skin reduces wrinkle.By adding in 0.6 part~1.05 parts of olibanum resin extract, With certain detumescence effect, additionally it is possible to reduce the shouting pain of skin, thorn when being especially adapted for use in dry and comfortable weather after skin dehydration Bitterly.Especially 1.1 parts~1.77 parts of Pimenta racemosa leaf oil, 0.4 part~0.9 part of hydrolyzed wheat protein and olibanum resin extract 0.6 part~1.05 parts collaborations play inhibitory action in use, can further enhance for some viruses, possess better moisturizing And antioxidant effect and the shouting pain that skin can be further reduced.Preferably, the mass parts of Pimenta racemosa leaf oil are 1.34 Part~1.76 parts, the mass parts of hydrolyzed wheat protein are 0.63 part~0.7 part, and the mass parts of olibanum resin extract are 0.61 part ~0.97 part;It is furthermore preferred that the mass parts of Pimenta racemosa leaf oil are 1.42 parts, the mass parts of hydrolyzed wheat protein are 0.67 Part, the mass parts of olibanum resin extract are 0.71 part, so, it is possible to further enhance and play inhibition work for some viruses With possessing better moisturizing and antioxidant effect and the shouting pain of skin can be further reduced.
In one embodiment, the 3rd ingredient further includes 0.8 part~1.74 parts of Sage extract and Acacia decurrens extract 0.6 part~1.4 parts, by adding in 0.8 part~1.74 parts of Sage extract, Sage extract can delay to a certain extent Solution causes vasomotor dysfunction by autonomic nerve system dysfunction, can alleviate vegetative nervous disorder, so as to reduce hidrosis The problem of, it is particularly suitable for some easily nervous users to perspire.In addition, Sage extract also has anti-aging, mitigates pain Pain acts on, and can also alleviate the discomfort of skin.By adding in 0.6 part~1.4 parts of Acacia decurrens extract, can further enhance with The moistening effect of composition based on red autumnal leaves algae extract, especially, in 70 parts~85 parts of red autumnal leaves algae extract and coralline algae It is better, on the one hand, to enable to moistening effect more preferable, the opposing party can make when extract and Sage extract share The problem of obtaining on the basis of moisturizing, being further reduced hidrosis, can inhibit to perspire to a certain extent.Preferably, mouse The mass parts of tail grass extract are 1.14 parts~1.28 parts, and the mass parts of Acacia decurrens extract are 0.75 part~1.01 parts, more excellent Choosing, the mass parts of Sage extract are 1.23 parts, and the mass parts of Acacia decurrens extract are 0.94 part, so, it is possible so that Moistening effect is more preferable, enables on the basis of moisturizing, the problem of being further reduced hidrosis, can be to a certain extent Inhibit to perspire.
In one embodiment, 2 parts~6 parts of Nymphaea caerulea extract and cloves alabastrum extract are further included in the 3rd ingredient 3.4 parts~5.6 parts, in this way, by adding in 2 parts~6 parts of Nymphaea caerulea extract, Nymphaea caerulea extract has preferable ABTS freedom Base Scavenging activity, ABTS radicals scavengings vigor can be further enhanced up to more than 80% based on red autumnal leaves algae extract The anti-oxidation function of composition, so as to enhance the senile-resistant efficacy of the composition based on red autumnal leaves algae extract and whitening effect Fruit.Especially 2 parts~6 parts of Nymphaea caerulea extract makes together with epidermal stem cells active ingredient, red autumnal leaves algae extract and mannitol Used time, activity are held time longer, can extend bioactivity in red autumnal leaves algae extract and epidermal stem cells active ingredient The storage time of substance, also with certain bacteriostasis so that during the preservation of the composition based on red autumnal leaves algae extract Between it is longer.By adding in 3.4 parts~5.6 parts of cloves alabastrum extract, with 2 parts~6 parts of Nymphaea caerulea extract and mannitol and When red autumnal leaves algae extract is used together, there is certain inhibitory action to skin ulcer, it is especially suitable also with certain analgesic activity For sensitive skin, there are the skin of acne or dry and cracked and pain skin for some, discomfort can be reduced, additionally it is possible to skin Certain facilitation is played in the reparation of skin ulcer.Especially when epidermal stem cells active ingredient is used together, effect It becomes apparent.Preferably, the mass parts of the Nymphaea caerulea extract are 4.5 parts~5.7 parts, the matter of the cloves alabastrum extract It is 4.8 parts~5.2 parts to measure part, it is furthermore preferred that the mass parts of the Nymphaea caerulea extract are 5.4 parts, the cloves bud extraction The mass parts of object are 5.1 parts, in this way, better.
In one embodiment, the 3rd ingredient further includes 0.7 part~0.9 part of sturgeon roe sauce extract, Murraya jasminorage leaf extraction 2 parts~2.8 parts of 1.2 parts~1.5 parts of object, 1.2 parts~1.7 parts of coptis root extract and bitter almond oil, in this way, sturgeon roe sauce It, being capable of preferably skin care containing abundant trace element, mineral salt, protein, amino acid and aliphatic acid, additionally it is possible to make skin Skin is more fine and smooth, and Murraya jasminorage leaf extract relieves pain effect and detumescence effect with certain, is used for red autumnal leaves algae When in the composition based on extract, the discomfort of skin can be alleviated, especially alleviate feeling of pain during skin dehydration, the coptis Root extract has the function of certain antibacterial anti-inflammatory, has certain inhibitory action to psoriasis etc., can so keep skin table The health in face, and the growth of skin surface microorganism can be reduced, especially in 0.7 part~0.9 part of sturgeon roe sauce extract, nine 2 parts~2.8 parts 1.2 parts~1.5 parts of Herba Pelargonii Graveolentis extract, 1.2 parts~1.7 parts of coptis root extract and bitter almond oil combinations When, there is preferable synergistic effect, the discomfort of skin can be further reduced, there is preferable nutrition moisten effect to skin, It can further provide for certain anti-ageing crease-resistant health-care effect, additionally it is possible to improve the surface tension of skin.Preferably, sturgeon roe sauce The mass parts of extract are 0.76 part~0.88 part, and the mass parts of Murraya jasminorage leaf extract are 1.32 parts~1.49 parts, coptis root The mass parts of extract are 1.25 parts~1.51 parts, and the mass parts of bitter almond oil are 2 parts~2.78 parts, it is furthermore preferred that sturgeon The mass parts of sub- sauce extract are 0.82 part, and the mass parts of Murraya jasminorage leaf extract are 1.47 parts, the quality of coptis root extract Part is 1.33 parts, and the mass parts of bitter almond oil are 2.1 parts, so, it is possible to be further reduced the discomfort of skin, have to skin Preferable nutrition moisten effect, can further provide for certain anti-ageing crease-resistant health-care effect, additionally it is possible to improve the surface of skin Tension.
In one embodiment, the 3rd ingredient further includes 0.5 part~0.9 part of citron fruit powder, 0.5 part of gynostemma pentaphyllum leaf extract ~0.8 part and 0.2 part~0.8 part of peach resin extract, in this way, citron fruit powder has preferable skin conditioning functions, gynostemma pentaphylla Leaf extract has a variety of gynosaponins, can enhance body immune function, additionally it is possible to reduce the grease of skin surface, simultaneously Also there is preferable anti-oxidation function, additionally it is possible to reduce the generation of skin ulcer, peach resin extract has skin preferable Crease-resistant tender skin effect, especially in 0.5 part~0.9 part of citron fruit powder, 0.5 part~0.8 part of gynostemma pentaphyllum leaf extract and peach fat It is better during 0.2 part~0.8 part combination of extract.Preferably, the mass parts of citron fruit powder are 0.54 part~0.77 part, are twisted The mass parts of the blue leaf extract of stock are 0.63 part~0.72 part, and the mass parts of peach resin extract are 0.47 part~0.63 part, more Preferably, the mass parts of citron fruit powder are 0.72 part, and the mass parts of gynostemma pentaphyllum leaf extract are 0.65 part, peach resin extract Mass parts are 0.57 part, so, it is possible further have preferable skin conditioning functions, can enhance body immune function, The grease of skin surface can also be reduced, while also there is preferable anti-oxidation function, additionally it is possible to reduce the generation of skin ulcer And with preferable crease-resistant tender skin effect.
In one embodiment, the 3rd ingredient further includes 0.3 part~1.1 part, mao nozzle label of flat peach Cactus Pedicel extract and carries Take 0.9 part~1.6 parts of 0.5 part~1.2 parts of object and Semen Coicis extract.By adding in flat peach Cactus Pedicel extract (Opuntia Ficus-indica Stem Extract) 0.3 part~1.1 parts, enable to composition based on red autumnal leaves algae extract Moistening effect further enhances, and peach Cactus Pedicel extract can also soothe the skin surface so that and skin surface is more elastic, this Outside, peach Cactus Pedicel extract also has certain antiallergic effect, can improve the inferior health of skin.It is carried by adding in hair nozzle label 0.5 part~1.2 parts of object is taken, when being shared with flat peach Cactus Pedicel extract and coral algae extract, can be further enhanced with red The moistening effect of composition based on leaf algae extract.By adding in 0.9 part~1.6 parts of Semen Coicis extract, have preferable Whitening, freckle effect, also with extremely strong anti-oxidation characteristics, with flat peach Cactus Pedicel extract, coral algae extract and Hair nozzle label extract is when being used in conjunction with, can whitening, freckle effect it is more preferable.Preferably, the quality of flat peach Cactus Pedicel extract Part is 0.41 part~0.84 part, and the mass parts of hair nozzle label extract are 0.58 part~0.88 part, the mass parts of Semen Coicis extract For 0.97 part~1.28 parts;It is furthermore preferred that the mass parts of flat peach Cactus Pedicel extract are 0.49 part, the matter of hair nozzle label extract It is 0.73 part to measure part, and the mass parts of Semen Coicis extract are 1.22 parts, so, it is possible to further enhance using red autumnal leaves algae extract as The moistening effect of the composition on basis, and with preferable whitening, freckle effect, also with extremely strong anti-oxidation characteristics.
In one embodiment, the 3rd ingredient further includes 0.42 part~0.51 part of African pendent lamp tree bark extract and poly- paddy 0.01 part~0.04 part of propylhomoserin, in this way, by adding in African 0.42 part of pendent lamp tree (KIGELIA AFRICANA) bark extract ~0.51 part, activity to cyclooxygenase and there is certain inhibitory action to the release of interleukin, so as to certain Antiphlogistic effects during applied in shin moisturizer, help against gravity caused damaging side effect on the skin;It is poly- by adding in 0.01 part~0.04 part of glutamic acid, polyglutamic acid can form network of rivers film on the skin of surface layer, can reduce the loss of moisture, tool There is the effect of highly effective water-keeping, polyglutamic acid can enhance African pendent lamp when African pendent lamp tree bark extract is used together Bark extract is set to the antiphlogistic effects of skin so that skin is more easy to repair from damage, be particularly suitable for some ulcer or The skin of slight acne rash class.Preferably, the mass parts of African pendent lamp tree bark extract are 0.43 part~0.5 part, polyglutamic acid Mass parts be 0.02 part~0.04 part;It is furthermore preferred that the mass parts of African pendent lamp tree bark extract are 0.46 part, polyglutamic The mass parts of acid are 0.03 part, so, it is possible to further enhance African pendent lamp tree bark extract to the antiphlogistic effects of skin, make Skin is obtained to be more easy to repair from damage, through experiment, the composition based on using the above-mentioned algae extract by red autumnal leaves in a continuous week Afterwards, whelk and blackening can be made to be obviously reduced more than 30%.
In one embodiment, the 3rd ingredient further includes 0.000025 part~0.000039 part of oligopeptides -6 and streptococcus lactis peptide It 0.00008 part~0.00012 part, so, it is possible to promote the synthesis of skin surface collagen so that skin is more elastic, and By adding in 0.00008 part~0.00012 part of streptococcus lactis peptide, wherein streptococcus lactis peptide (Nisin), also known as nisin is right Various bacteria has good inhibiting effect, can reduce the enrichment of skin surface pernicious bacteria, enable to skin surface more For health.Preferably, the mass parts of oligopeptides -6 are 0.000032 part~0.000035 part, and the mass parts of streptococcus lactis peptide are 0.000097 part~0.000105 part, it is preferred that the mass parts of oligopeptides -6 are 0.000034 part, and the mass parts of streptococcus lactis peptide are It 0.000103 part, so, it is possible so that skin is more elastic, additionally it is possible to the enrichment of skin surface pernicious bacteria is further reduced, Enable to skin surface more healthy.
Composition based on the above-mentioned algae extract by red autumnal leaves, can play preferable moistening effect, additionally it is possible to play compared with Good sun-proof result, it is preferable to the shield effectiveness of the ultraviolet light of 280nm~400nm wavelength.In addition, it can also alleviate skin The problem of blackening occurred because of being exposed to the sun, has certain repair to the skin of sunburn.Also, it also has preferable Radical scavenging activity, can the free chain reaction caused by ultraviolet light play the role of further suspension, so as to It is further reduced injury of the ultraviolet light to skin.
It should be noted that the content of the floridosides in red autumnal leaves algae extract is to the group based on red autumnal leaves algae extract Closing moistening effect and sun-proof result of object etc. has important influence.In order to improve containing for the floridosides in red autumnal leaves algae extract Amount, the present invention also provides a kind of preparation methods of red autumnal leaves algae extract.For another example, as above described in any embodiment with red autumnal leaves algae The red autumnal leaves algae extract of composition based on extract is prepared using the preparation method of red autumnal leaves algae extract.For another example, please Refering to Fig. 1, the preparation method of red autumnal leaves algae extract includes the following steps:
S110:Collect fresh red autumnal leaves algae;
For example, fresh red autumnal leaves algae refer to acquisition after 0.1 it is small when~48 it is small when red autumnal leaves algae.Preferably, fresh red autumnal leaves Algae refer to acquisition after 0.1 it is small when~24 it is small when red autumnal leaves algae.In this way, convenient for improving in the red autumnal leaves algae extract being subsequently prepared The content of floridosides.
S120:The red autumnal leaves algae is crushed into operation, obtains red autumnal leaves algae powder;
For example, the red autumnal leaves algae is operated by low-temperature grinding, red autumnal leaves algae powder is obtained;For another example, it is Celsius 2 degrees Celsius~10 Operation is crushed to fresh red autumnal leaves algae at a temperature of degree.For another example, the average grain diameter of red autumnal leaves algae powder is 0.4 millimeter~1.2 millis Rice, it is preferred that the average grain diameter of red autumnal leaves algae powder is 0.5 millimeter~0.8 millimeter, it is furthermore preferred that the average grain diameter of red autumnal leaves algae powder is 0.6 millimeter~0.7 millimeter.It so, it is possible to further improve containing for floridosides in the red autumnal leaves algae extract being subsequently prepared Amount.
S130:The red autumnal leaves algae powder is added in the ethanol solution of sodium acetate and extracts operation, obtains mixed extract;
Operation is extracted in ethanol solution by the way that the red autumnal leaves algae powder to be added in sodium acetate, obtains mixed extract, In order to which the red autumnal leaves algae sugar in red autumnal leaves algae is extracted.It is to be particularly noted that compared with traditional only by ethyl alcohol The floridosides in red autumnal leaves algae is extracted, by using the ethanol solution of sodium acetate extracts the floridosides in red autumnal leaves algae, energy Enough further improve the content of floridosides in the red autumnal leaves algae extract being subsequently prepared.For example, the ethyl alcohol is concentration is 75% ethanol solution.For another example, the time of the extraction operation for 3.5 it is small when~6 it is small when.For another example, the temperature of the extraction operation It spends for 55 degrees Celsius~70 degrees Celsius.For another example, the mass volume ratio of the sodium acetate and described 75% ethanol solution is:0.8 Gram:1000 milliliters, i.e., the concentration that 0.8 gram of sodium acetate is dissolved to 1000 milliliters be in 75% ethanol solution so, it is possible into The content of floridosides, can make floridosides yield 3.2% in the red autumnal leaves algae extract that the raising of one step is subsequently prepared Above the dry weight of red autumnal leaves algae powder (be subject to).
In one embodiment, the solid-liquid ratio of the red autumnal leaves algae powder and the ethanol solution of the sodium acetate is 1g:(16ml~ 19ml), it is preferred that the solid-liquid ratio of the red autumnal leaves algae powder and the ethanol solution of the sodium acetate is 1g:(17.8ml~18.2ml), It is furthermore preferred that the solid-liquid ratio of the red autumnal leaves algae powder and the ethanol solution of the sodium acetate is 1g:18.1ml so, it is possible into one Step improves the content of floridosides in the red autumnal leaves algae extract that is subsequently prepared, can make floridosides yield 3.22% with Upper the dry weight of red autumnal leaves algae powder (be subject to).
In order to further improve the content of floridosides in the red autumnal leaves algae extract being subsequently prepared, in an embodiment, The extraction operation operates for ultrasonic extraction, and for another example, the temperature of the ultrasonic extraction operation is 55 degrees Celsius~65 degrees Celsius, again Such as, the time of the ultrasonic extraction operation is 40 minutes~70 minutes, and for another example, the supersonic frequency is 50kHz~70kHz, such as This, on the one hand, the time of extraction operation can be shortened, on the other hand, additionally it is possible on the basis of the operating time is shortened, further The content of floridosides in the red autumnal leaves algae extract being subsequently prepared is improved, floridosides yield can be made more than 3.25% The dry weight of red autumnal leaves algae powder (be subject to).
S140:The mixed extract is filtered operation, obtains filtered fluid;
In the present embodiment, the mixed extract is subjected to the filter operation using multilayer gauze.For another example, using three layers Gauze~six layer gauze is filtered operation.Preferably, it is filtered operation using three layers of gauze.
S150:The filtered fluid is subjected to concentration operation, obtains concentrate;
For example, the concentration operation is carried out using revolving evaporimeter.For another example, the volume of the concentrate and the filtered fluid Than for 1:10, i.e., by ten times of the filtered fluid volume concentration.In this way, facilitate subsequent extraction operation, additionally it is possible to reduce or go Except the amount of ethyl alcohol in concentrate.
S160:The concentrate is added in into ethyl acetate and carries out extracting operation, obtains extract liquor;
For example, the volume ratio of the concentrate and the ethyl acetate is 1:1.For another example, the extracting operation is in extractor Middle progress.It is to be particularly noted that operation is extracted to red autumnal leaves algae powder in ethanol solution by adding in sodium acetate early period, When Extracting temperature is 55 degrees Celsius or more, can make to carry upper part sodium ion on the hydroxyl of floridosides, so as to make Solubility higher of the floridosides in concentrate in ethyl acetate is obtained, is conducive to subsequent extracting operation, extraction can be improved The efficiency taken reduces the number of extracting operation, it is only necessary to which single extraction operates, you can has preferable effect of extracting, can make red algae The glucosides yield dry weight of red autumnal leaves algae powder (be subject to) more than 3.2%.
S170:The extract liquor using filter membrane is filtered, obtains filtrate;Wherein, the molecular weight of the filter membrane is 500 The dalton of dalton~5000.
By the way that the extract liquor is filtered using filter membrane, filtrate is obtained, to remove most of albumen in extract liquor Matter.Preferably, the molecular weight of the filter membrane is 5000 dalton.It so, it is possible most of egg in the removal extract liquor built up White matter, and the rate of filtration is very fast.
S180:Operation is dried in the filtrate, obtains red autumnal leaves algae extract.
For example, the filtrate is dried operation using Rotary Evaporators, red autumnal leaves algae extract is obtained.Especially needed theory It is bright, during Rotary Evaporators are dried, wherein remaining ethyl acetate can volatilize totally.
The preparation method of above-mentioned red autumnal leaves algae extract, compared with it is traditional extract only by ethyl alcohol it is red in red autumnal leaves algae Algae glucosides extracts the floridosides in red autumnal leaves algae by using the ethanol solution of sodium acetate, can further improve follow-up system The content of floridosides in standby obtained red autumnal leaves algae extract.
It is for another example, described with red the present invention also provides a kind of preparation method of the composition based on algae extract by red autumnal leaves Composition based on leaf algae extract is the as above composition based on red autumnal leaves algae extract described in any embodiment. For another example, the composition based on red autumnal leaves algae extract as above described in any embodiment is used using red autumnal leaves algae extract as base The preparation method of the composition of plinth is prepared.For another example, referring to Fig. 2, composition based on the algae extract by red autumnal leaves Preparation method include the following steps:
S210:80 degrees Celsius~84 degrees Celsius are heated to after each component in the first composition is mixed, obtains first Product.
For example, the step S210 is specially:80 degrees Celsius are heated to after each component in the first composition is mixed ~82 degrees Celsius, obtain the first product.For another example, the step S210 is specially:Each component in the first composition is mixed After be heated to 81.5 degrees Celsius, obtain the first product.It so, it is possible to make each component in first composition preferably to mix, and energy Follow-up first composition and second composition is enough made preferably to be mixed to form lotion.
S220:It is heated to seething with excitement after each component of the second composition is mixed, and it is Celsius to be cooled to 80 degrees Celsius~84 The second product is obtained after degree.
For example, the step S220 is specially:It is heated to seething with excitement after each component of the second composition is mixed, and cools down The second product is obtained after to 80 degrees Celsius~82 degrees Celsius.For another example, the step S220 is specially:By each of the second composition It is heated to seething with excitement after component mixing, and the second product is obtained after being cooled to 81.5 degrees Celsius.It so, it is possible to make in first composition Each component preferably mixes, and follow-up first composition and second composition can be made preferably to be mixed to form lotion.For another example, the boiling It is 100 degrees Celsius to rise to temperature, and for another example, each component by the second composition is heated to boiling after mixing and is specially:It will 100 degrees Celsius are heated to after each component mixing of the second composition.
S230:Second product is added in the first product and is uniformly mixed, and it is Celsius to be cooled to 43 degrees Celsius~46 Third product is obtained after degree.
For example, the S230 is specially:Second product is added in the first product and is uniformly mixed, and is cooled to 44 Degree Celsius~45 degrees Celsius after obtain third product.For another example, the S230 is specially:Second product is added to the first production It is uniformly mixed in object, and third product is obtained after being cooled to 44.5 degrees Celsius.
S240:It is added in third product and is uniformly mixed after ternary each component is mixed, obtain the 4th product.
S250:4th product is cooled to after room temperature to get to the combination based on the algae extract by red autumnal leaves Object.
For example, the room temperature is 7 degrees Celsius~30 degrees Celsius.
The preparation method of composition based on the above-mentioned algae extract by red autumnal leaves be prepared using red autumnal leaves algae extract as The composition on basis, can play preferable moistening effect, additionally it is possible to preferable sun-proof result is played, to 280nm~400nm The shield effectiveness of the ultraviolet light of wavelength is preferable.In addition, it can also alleviate the problem of blackening that skin occurs because of being exposed to the sun, it is right The skin of sunburn has certain repair.Also, it also has preferable radical scavenging activity, and ultraviolet light can be made Into free chain reaction play the role of further suspension, so as to be further reduced injury of the ultraviolet light to skin.
In order to further illustrate the composition based on the above-mentioned algae extract by red autumnal leaves, continue in conjunction with specific embodiments To be explained.
Embodiment 1:Composition based on a kind of algae extract by red autumnal leaves, including first composition, second composition and the 3rd Ingredient;The first composition, the second composition and the ternary mass ratio are 1:1:0.23.The first composition bag Include each component of following mass parts:Double -13.5 parts of ethylhexylphenol methylamino benzene piperazine, 4.5 parts of octyl methoxycinnamate, sugarcane 8.7 parts of 4.7 parts of sugar fatty acid ester, 1.9 parts of cetostearyl alcohol, 1.18 parts of hexadecanol and isobutyl palmitate.The second composition Include each component of following mass parts:7.8 parts of methylene bis-benzotriazolyl tetramethyl butyl phenol, xanthans 0.22 part, nanometer 34.9 parts of 2.8 parts of titanium dioxide, 2.3 parts of mannitol, 0.11 part of hydroxyethyl cellulose and deionized water.The three one-tenth subpackages Include each component of following mass parts:77.5 parts of red autumnal leaves algae extract, 0.00029 part of fibroblast growth factor and sterile water 84 parts.Wherein, the preparation method of the composition based on red autumnal leaves algae extract is as follows:By each component in the first composition 80 degrees Celsius~84 degrees Celsius are heated to after mixing, obtains the first product.It is heated after each component of the second composition is mixed To boiling, and the second product is obtained after being cooled to 81.5 degrees Celsius.Second product is added in the first product and is mixed It is even, and obtain third product after being cooled to 44.5 degrees Celsius.It is added to after ternary each component is mixed in third product It is uniformly mixed, obtains the 4th product.By the 4th product be cooled to after room temperature to get to described using red autumnal leaves algae extract as base The composition of plinth.
Embodiment 2:On the basis of the composition based on red autumnal leaves algae extract of embodiment 1, in the 3rd ingredient also Including 8.5 parts of epidermal stem cells active ingredient.
Embodiment 3:On the basis of the composition based on red autumnal leaves algae extract of embodiment 2, in the 3rd ingredient also Include the component of following mass parts:0.67 part of 1.42 parts of Pimenta racemosa leaf oil and hydrolyzed wheat protein.
Embodiment 4:On the basis of the composition based on red autumnal leaves algae extract of embodiment 3, in the 3rd ingredient also Include the component of following mass parts:0.94 part of 1.23 parts of Sage extract and Acacia decurrens extract.
Embodiment 5:On the basis of the composition based on red autumnal leaves algae extract of embodiment 4, in the 3rd ingredient also Include the component of following mass parts:5.1 parts of 5.4 parts of Nymphaea caerulea extract and cloves alabastrum extract.
Embodiment 6:On the basis of the composition based on red autumnal leaves algae extract of embodiment 5, in the 3rd ingredient also Include the component of following mass parts:0.82 part of sturgeon roe sauce extract, 1.47 parts of Murraya jasminorage leaf extract, coptis root extract 1.33 parts and 2.1 parts of bitter almond oil.
Embodiment 7:On the basis of the composition based on red autumnal leaves algae extract of embodiment 6, in the 3rd ingredient also Include the component of following mass parts:0.57 part of 0.72 part of citron fruit powder, 0.65 part of gynostemma pentaphyllum leaf extract and peach resin extract.
Embodiment 8:On the basis of the composition based on red autumnal leaves algae extract of embodiment 7, in the 3rd ingredient also Include the component of following mass parts:0.49 0.73 part of part, mao nozzle label extract of flat peach Cactus Pedicel extract and coix seed extraction 1.22 parts of object.
Embodiment 9:On the basis of the composition based on red autumnal leaves algae extract of embodiment 8, in the 3rd ingredient also Include the component of following mass parts:0.03 part of 0.46 part of African pendent lamp tree bark extract and polyglutamic acid.
Embodiment 10:On the basis of the composition based on red autumnal leaves algae extract of embodiment 9, in the 3rd ingredient also Include the component of following mass parts:0.000103 part of -60.000034 parts of oligopeptides and streptococcus lactis peptide.
Comparative example 1:Glycerine.
By the composition based on red autumnal leaves algae extract that embodiment 1 to embodiment 10 is prepared according to《QB/T 1684-2015 cosmetics inspection rules》After qualification of testing, using 11 groups of volunteers, skin of face is continued respectively It is on probation, fortnight is used continuously, respectively the skin after its use of questionnaire survey, specifically includes that skin is more fine and smooth, makes It is tailed off with rear salubrious sensation, small pox, whitening function, sun-proof result.It is carried out according to fabulous, good, general and invalid four grades Questionnaire survey, statistical average situation.Invalid, general, good, fabulous four grades that using effect is divided into, the results are shown in table below.
Table 1:1 Questionnaire results figure of 1~embodiment of embodiment 10 and comparative example
It can be seen that the composition based on the above-mentioned algae extract by red autumnal leaves, can play preferable moistening effect, moreover it is possible to The problem of enough playing preferable sun-proof result, the blackening that skin occurs because of being exposed to the sun can also be alleviated, to the skin of sunburn With certain repair.Also, its also have preferable radical scavenging activity, can caused by ultraviolet light free radical Further suspension is played the role of in chain reaction, so as to be further reduced injury of the ultraviolet light to skin.
The present invention also provides a kind of applicator system, the applicator system include as above described in any embodiment with red autumnal leaves Composition based on algae extract.For another example, the as above combination based on red autumnal leaves algae extract described in any embodiment Object is smeared using applicator system and used, and so, it is possible preferably to use based on red autumnal leaves algae extract convenient for user's smearing Composition, to play its function.For another example, the applicator system includes control painting pen and the combination based on red autumnal leaves algae extract Object, composition based on the algae extract by red autumnal leaves for as above described in any embodiment using red autumnal leaves algae extract as base The composition of plinth.The painting pen includes cylinder, Massage Department, spring, ball and supports bar, and the cylinder offers accommodating cavity, The accommodating cavity is equipped with the as above composition based on red autumnal leaves algae extract described in any embodiment, in other words, institute The composition based on red autumnal leaves algae extract is stated to be placed in the accommodating cavity.The Massage Department connects the cylinder, described Massage Department has hollow structure, and the Massage Department is provided with fixed link adjacent to one end of the cylinder, and the Massage Department is away from institute The end for stating cylinder offers sample outlet hole, and the ball part is placed in the sample outlet hole, and the first end for supporting bar connects The ball is connect, the second end for supporting bar connects the first end of the spring, and the second end connection of the spring is described solid Fixed pole, the ball are described to open for supporting the bar compression spring described in the drive when the ball is subject to external pressure Sample outlet hole, the ball are additionally operable to go out sample described in closing under the action of the restoring force of the spring when external pressure disappears Hole.In this way, applicator system described above, can preferably smear the composition based on red autumnal leaves algae extract.For another example, The shape adaptation of the sample outlet hole is in the shape of the ball.For another example, the cylinder is spirally connected the Massage Department.
In order to preferably install the spring, in an embodiment, storage tank is provided in the fixed link, the spring Second end is placed in the storage tank, and for another example, the second end of the spring is abutted with the bottom wall of the storage tank.For another example, institute The second end of spring is stated in the storage tank, for another example, the second end of the spring is embedded in the storage tank and institute The second end for stating spring is abutted with the bottom wall of the storage tank.For another example, the bar that supports is provided with mounting groove, and the of the spring One end is placed in the mounting groove, and for another example, the first end of the spring is abutted with the bottom wall of the mounting groove.For another example, it is described The first end of spring is in the mounting groove, and for another example, the first end of the spring is in the mounting groove and described The first end of spring is abutted with the bottom wall of the mounting groove, so, it is possible preferably to install the spring.
In order to which the ball is enable preferably to close and open the sample outlet hole, in an embodiment, it is described go out sample Hole has circular cross-section, and for another example, the sample outlet hole has arc shaped inside wall, and for another example, the sample outlet hole is along close to the cylinder Direction gradually broadens, and for another example, the diameter in the section at the most narrow place of the sample outlet hole is less than the diameter of the ball, so, it is possible to make The ball preferably can close and open the sample outlet hole.
In order to play preferable massage effect, in an embodiment, the lateral wall of the Massage Department is provided with burr, again Such as, the lateral wall of the Massage Department is provided with several burrs, and for another example, several burrs are circularly and evenly distributed in the massage On the lateral wall in portion, it so, it is possible to make the Massage Department that can also play preferable massage effect.
It is understood that during ball use, surface easily grows bacterium.In one embodiment, the ball surface Antimicrobial coating is provided with, so, it is possible to set antimicrobial coating on the ball surface, it can be inhibited during ball use The growth and breeding of surface bacteria.For another example, the antimicrobial coating includes following ingredient:Nano titanium powder and polyureas-resinous copolymeric siloxane Object, wherein, the mass ratio of the nano titanium powder and polyureas-resinous copolymeric siloxane object is 1:(3~4.5), it is preferred that the nano-titanium The mass ratio of powder and polyureas-resinous copolymeric siloxane object is 1:(3.9~4.2), it is furthermore preferred that the nano titanium powder and polyureas-silicon tree The mass ratio of resin copolymer is 1:4.1, it so, it is possible preferably to inhibit the growth of ball surface bacteria during ball use And breeding.
It is described with red autumnal leaves algae extract in order to which the ball is enable preferably to smear when the sample outlet hole is opened Based on composition, in an embodiment, the first end for supporting bar offers rolling groove, and the ball part is placed in institute It states in rolling groove, and the ball can roll in the rolling groove, in this way, compressing institute when the ball is subject to external pressure State spring so that ball is to the direction displacement close to the cylinder, to open the sample outlet hole so that flow in accommodating cavity described Composition based on the algae extract by red autumnal leaves of the hollow structure of Massage Department is flowed out by the sample outlet hole, is then passed through The ball is rolled, can preferably smear the composition based on red autumnal leaves algae extract.For another example, opened in the ball When opening the sample outlet hole, the ball can roll.
In order to preferably preserve the composition based on red autumnal leaves algae extract, avoid based on red autumnal leaves algae extract The active ingredient of composition inactivates, and in an embodiment, the lateral wall of the cylinder, which is sticked, thermoelectric module, and thermoelectric module is used In providing refrigerating function to the cylinder, in this way, by thermoelectric module, accommodating cavity can be made to maintain relatively low temperature.Again Such as, the thermoelectric module is also referred to as semiconductor chilling plate.For another example, the cylinder is additionally provided with power module, the power supply mould Block connects the thermoelectric module.For another example, side of the thermoelectric module away from the accommodating cavity, which is also sticked, heat dissipation graphite Film, in this way, by the graphite film that radiates the heat of the heating side of thermoelectric module can quickly scattered away, so as to further improve Thermoelectric module is to the refrigeration effect of accommodating cavity.For another example, the thickness of the heat dissipation graphite film is 0.05 millimeter~3 millimeters, preferably , the thickness of the heat dissipation graphite film is 0.8 millimeter~1.4 millimeters, it is furthermore preferred that the thickness of the heat dissipation graphite film is 1.2 Millimeter, the heat that so, it is possible the heating side for making thermoelectric module are quickly scattered away, so, it is possible to further improve thermoelectricity system The cold refrigeration effect to accommodating cavity.So, it is possible preferably to preserve the composition based on red autumnal leaves algae extract, slow down with The active ingredient inactivation of composition based on red autumnal leaves algae extract.For another example, the lateral wall of the cylinder is sticked the thermoelectricity system Cold.It so, it is possible preferably to preserve the composition based on red autumnal leaves algae extract, avoid based on red autumnal leaves algae extract Composition active ingredient inactivation.
Composition based on the above-mentioned algae extract by red autumnal leaves, can play preferable moistening effect, additionally it is possible to play compared with Good sun-proof result, it is preferable to the shield effectiveness of the ultraviolet light of 280nm~400nm wavelength.In addition, it can also alleviate skin The problem of blackening occurred because of being exposed to the sun, has certain repair to the skin of sunburn.Also, it also has preferable Radical scavenging activity, can the free chain reaction caused by ultraviolet light play the role of further suspension, so as to It is further reduced injury of the ultraviolet light to skin.
It should be noted that the mass parts can be understood as gram, milligram, kilogram, jin, kilogram, pound, ton etc..With gram Exemplified by, for example, 1 mass parts can be 0.001g, 0.01g, 0.02g, 0.05g, 0.1g, 0.2g, 0.5g, 1g, 2g, 3g, 4g, 5g, 10g, 15g, 20g, 30g, 50g, 80g, 100g, 500g, 1000g, 5000g, 10000g or 50000g etc., and it is without being limited thereto. And so on.
Each technical characteristic of embodiment described above can be combined arbitrarily, to make description succinct, not to above-mentioned reality It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited In contradiction, the scope that this specification is recorded all is considered to be.
Embodiment described above only expresses the several embodiments of the present invention, and description is more specific and detailed, but simultaneously It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that come for those of ordinary skill in the art It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the protection of the present invention Scope.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.

Claims (9)

1. the composition based on a kind of algae extract by red autumnal leaves, which is characterized in that including first composition, second composition and the 3rd Ingredient;
The first composition includes each component of following mass parts:Double -11 parts~14 parts of ethylhexylphenol methylamino benzene piperazine, first 4 parts~6 parts of oxygroup cinnamic acid monooctyl ester, 4.5 parts~4.9 parts of sucrose fatty ester, 1.5 parts~2.1 parts of cetostearyl alcohol, hexadecanol 1.1 parts~1.25 parts and 8.5 parts~10 parts of isobutyl palmitate;
The second composition includes each component of following mass parts:7.5 parts of methylene bis-benzotriazolyl tetramethyl butyl phenol~ 8.5 parts, 0.15 part~0.25 part of xanthans, 2.5 parts~3.1 parts of nano-titanium dioxide, 2 parts~2.5 parts of mannitol, ethoxy it is fine Dimension plain 0.1 part~0.12 part and 34 parts~35 parts of deionized water;
3rd ingredient includes each component of following mass parts:70 parts~85 parts of red autumnal leaves algae extract, fibroblastic growth 80 parts~85 parts of 0.00015 part~0.00032 part of the factor and sterile water;
Wherein, the first composition, the second composition and the ternary mass ratio are 1:1:" 0.2~0.25 ".
2. the composition based on the algae extract according to claim 1 by red autumnal leaves, which is characterized in that the 3rd ingredient Further include 5 parts~9 parts of epidermal stem cells active ingredient.
3. the composition based on the algae extract according to claim 1 by red autumnal leaves, which is characterized in that the fibrocyte Growth factor is recombination human basic fibroblast growth factor.
4. the composition based on the algae extract according to claim 1 by red autumnal leaves, which is characterized in that the first one-tenth described Divide, the second composition and the ternary mass ratio are 1:1:" 0.22~0.24 ".
5. the composition based on the algae extract according to claim 1 by red autumnal leaves, which is characterized in that the first one-tenth described Divide, the second composition and the ternary mass ratio are 1:1:0.23.
6. the preparation method of the composition based on a kind of algae extract by red autumnal leaves, which is characterized in that described to be extracted with red autumnal leaves algae Composition based on object is the composition based on red autumnal leaves algae extract as described in claim 1, the preparation method Include the following steps:
80 degrees Celsius~84 degrees Celsius are heated to after each component in the first composition is mixed, obtains the first product;
Will the second composition each component mix after be heated to seething with excitement, and the is obtained after being cooled to 80 degrees Celsius~84 degrees Celsius Two products;
Second product is added in the first product and is uniformly mixed, and the is obtained after being cooled to 43 degrees Celsius~46 degrees Celsius Three products;
It is added in third product and is uniformly mixed after ternary each component is mixed, obtain the 4th product;
4th product is cooled to after room temperature to get to the composition based on the algae extract by red autumnal leaves.
7. the preparation method of the composition based on the algae extract according to claim 6 by red autumnal leaves, which is characterized in that will 80 degrees Celsius~82 degrees Celsius are heated to after each component mixing in the first composition, obtains first product.
8. the preparation method of the composition based on the algae extract according to claim 7 by red autumnal leaves, which is characterized in that will 81.5 degrees Celsius are heated to after each component mixing in the first composition, obtains first product.
9. the preparation method of the composition based on the algae extract according to claim 6 by red autumnal leaves, which is characterized in that will Second product is added in the first product and is uniformly mixed, and the third product is obtained after being cooled to 44.5 degrees Celsius.
CN201810107585.5A 2018-02-02 2018-02-02 Composition based on red autumnal leaves algae extract and preparation method thereof Withdrawn CN108113909A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112494352A (en) * 2020-12-22 2021-03-16 珠海伊斯佳科技股份有限公司 Composition for resisting aging and repairing aged skin and preparation method and application thereof

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Publication number Priority date Publication date Assignee Title
CN105395434A (en) * 2015-12-21 2016-03-16 宁波大学 Application of floridoside to cosmetics
CN105434327A (en) * 2016-01-22 2016-03-30 蔡婷婷 Total-effect type skin-moistening sun cream
CN106333867A (en) * 2016-10-27 2017-01-18 广州市玮弘祺生物科技有限责任公司 Sun-screening composition and preparation method and application thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105395434A (en) * 2015-12-21 2016-03-16 宁波大学 Application of floridoside to cosmetics
CN105434327A (en) * 2016-01-22 2016-03-30 蔡婷婷 Total-effect type skin-moistening sun cream
CN106333867A (en) * 2016-10-27 2017-01-18 广州市玮弘祺生物科技有限责任公司 Sun-screening composition and preparation method and application thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112494352A (en) * 2020-12-22 2021-03-16 珠海伊斯佳科技股份有限公司 Composition for resisting aging and repairing aged skin and preparation method and application thereof

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