CN108102047A - Hydrogel - Google Patents
Hydrogel Download PDFInfo
- Publication number
- CN108102047A CN108102047A CN201611054914.1A CN201611054914A CN108102047A CN 108102047 A CN108102047 A CN 108102047A CN 201611054914 A CN201611054914 A CN 201611054914A CN 108102047 A CN108102047 A CN 108102047A
- Authority
- CN
- China
- Prior art keywords
- hydrogel
- monomer
- methyl
- hydrophilic
- hydrogel according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F289/00—Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds not provided for in groups C08F251/00 - C08F287/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/04—Oxygen-containing compounds
- C08K5/05—Alcohols; Metal alcoholates
- C08K5/053—Polyhydroxylic alcohols
-
- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C7/00—Optical parts
- G02C7/02—Lenses; Lens systems ; Methods of designing lenses
- G02C7/04—Contact lenses for the eyes
- G02C7/049—Contact lenses having special fitting or structural features achieved by special materials or material structures
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K2201/00—Specific properties of additives
- C08K2201/014—Additives containing two or more different additives of the same subgroup in C08K
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Ophthalmology & Optometry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- General Health & Medical Sciences (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention relates to a kind of hydrogel, the hydrophilic hydrogel is composed of the following components according to weight percent：Silicon-containing monomer：25~55%；Hydrophilic monomer：35~65%；Polyethyleneglycol diacrylate：1~3%；Crosslinking agent：1~2%；Adhesive：1~2%；Moisturizer：5~10%.Preparation process of the present invention is simple to operation, is suitble to large-scale production.
Description
Technical field
The present invention relates to a kind of hydrogels.
Background technology
, it is necessary to carry out moisturizing during contact lenses use, the contact lenses that common material makes cannot expire
The wearing demand of sufficient people to improve the oxygen permeability of hydrogel, achievees the purpose that eyeglass is enable to wear overnight, researcher
The silicone-hydrogel of high oxygen flow is capable of in research hotspot steering one after another.Silicone hydrogel material can combine organosilicon material
The flexibility of high oxygen permeability and hydrogel material can meet consumer's comfort and the needs of continuously wearing, and eliminate because wearing
Related symptoms caused by anoxic.Current many researchers are directed to silicon rubber or silicone-hydrogel surface hydrophilic modification, effect are good
Good but process conditions are complicated, are not suitable for scale processing.
In view of drawbacks described above, it is necessary to propose a kind of preparation method of new hydrophilic hydrogel.
The content of the invention
The object of the present invention is to provide a kind of preparation methods of new hydrogel.
Technical scheme is as follows：
A kind of hydrogel, which is characterized in that the hydrophilic hydrogel is composed of the following components according to weight percent：
Silicon-containing monomer：25~55%；
Hydrophilic monomer：35~65%；
Polyethyleneglycol diacrylate：1~3%；
Crosslinking agent：1~2%；
Adhesive：1~2%；
Moisturizer：5~10%.
Further, the silicon-containing monomer is methyl-two (trimethylsiloxane group)-methyl propyl methyl acid
Glyceride or methyl-two (trimethylsiloxane group)-methyl propyl methyl acid glyceride and methacryloxypropyl third
The mixture of base three (trimethylsiloxy group) silane composition.
Further, the hydrophilic monomer is one in caprolactone monomer, trimethylene carbonate monomer, glycolide monomer
Kind is a variety of.
Further, the crosslinking agent is styrene, a- methyl styrenes, acrylonitrile, acrylic acid, methacrylic acid, second
Any one of dialdehyde, aziridine.
Further, described adhesive is gelatin.
Further, the moisturizer is the one or more in glycerine, propylene glycol, sorbierite.
According to the above aspect of the present invention, the present invention has at least the following advantages：
In the present invention and hydrophilic monomers content is high.The embodiment of the present invention can be by preparing the hydrophilic water with moisturizer
Gel, anti-proteinosis performance is good, human eye comfortable wearing.And prepare silicone-hydrogel without surface be modified etc. post processings, can be straight
Connect wearing.Preparation process is simple to operation, is suitble to large-scale production.
Specific embodiment
With reference to embodiment, the invention will be further described.
Specific embodiment formula：
Silicon-containing monomer：25~55%；
Hydrophilic monomer：35~65%；
Polyethyleneglycol diacrylate：1~3%；
Crosslinking agent：1~2%；
Adhesive：1~2%；
Moisturizer：5~10%.
Specifically preparation method is：
Hydrophilic monomer, silicon-containing monomer, polyethyleneglycol diacrylate are dispersed in moisturizing dosage form under agitation
Into component A, crosslinking agent is formed into B component under agitation, B component and adhesive are added in component A, in vacuum condition
Lower formation gel layer, obtains hydrophilic hydrogel.
Embodiment 1
By-two (trimethylsiloxane group)-methyl propyl methyl acid glyceride of 25% methyl, 65% trimethylene
Carbonate monomer, 3% polyethyleneglycol diacrylate, which are scattered in after stirring evenly in 5% glycerine, forms component A, by 1%
Styrene forms B component under stiring, and the gelatin of B component and 1% is added in component A, forms gel under vacuum
Layer, obtains hydrophilic hydrogel.
Embodiment 2
By 55% methacryloxypropyl three (trimethylsiloxy group) silane, 35% glycolide monomer, 1% polyethylene glycol
Diacrylate, which is scattered in after stirring evenly in 7% propylene glycol, forms component A, and 2% titanium dioxide is formed B under stiring
The gelatin of B component and 1% is added in component A, forms gel layer under vacuum, obtains hydrophilic hydrogel by component.
Embodiment 3
By-two (trimethylsiloxane group)-methyl propyl methyl acid glyceride of 42% methyl and methacryl
Mixture, 44% trimethylene carbonate monomer, the 2% polyethylene glycol dipropyl of oxygen propyl group three (trimethylsiloxy group) silane composition
Olefin(e) acid ester, which is scattered in after stirring evenly in 10% propylene glycol, forms component A, and 2% acrylonitrile is formed B component under stiring,
The gelatin of B component and 1% is added in component A, forms gel layer under vacuum, obtains hydrophilic hydrogel.
The above is only the preferred embodiment of the present invention, is not intended to limit the invention, it is noted that for this skill
For the those of ordinary skill in art field, without departing from the technical principles of the invention, can also make it is several improvement and
Modification, these improvements and modifications also should be regarded as protection scope of the present invention.
Claims (6)
1. a kind of hydrogel, which is characterized in that the hydrophilic hydrogel is composed of the following components according to weight percent：
Silicon-containing monomer：25~55%；
Hydrophilic monomer：35~65%；
Polyethyleneglycol diacrylate：1~3%；
Crosslinking agent：1~2%；
Adhesive：1~2%；
Moisturizer：5~10%.
2. a kind of hydrogel according to claim 1, it is characterised in that：The silicon-containing monomer is the (trimethyl of methyl-two
Siloxy group)-methyl propyl methyl acid glyceride or methyl-two (trimethylsiloxane group)-methyl propyl first
The mixture of base glycerol acrylate and methacryloxypropyl three (trimethylsiloxy group) silane composition.
3. a kind of hydrogel according to claim 1, it is characterised in that：The hydrophilic monomer is caprolactone monomer, Sanya
One or more in methyl carbonic acid ester monomer, glycolide monomer.
4. a kind of hydrogel according to claim 1, it is characterised in that：The crosslinking agent is styrene, a- methylbenzene second
Any one of alkene, acrylonitrile, acrylic acid, methacrylic acid, glyoxal, aziridine.
5. a kind of hydrogel according to claim 1, it is characterised in that：Described adhesive is gelatin.
6. a kind of hydrogel according to claim 1, it is characterised in that：The moisturizer is glycerine, propylene glycol, sorbierite
In one or more.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611054914.1A CN108102047A (en) | 2016-11-25 | 2016-11-25 | Hydrogel |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611054914.1A CN108102047A (en) | 2016-11-25 | 2016-11-25 | Hydrogel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108102047A true CN108102047A (en) | 2018-06-01 |
Family
ID=62204269
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611054914.1A Pending CN108102047A (en) | 2016-11-25 | 2016-11-25 | Hydrogel |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108102047A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102964532A (en) * | 2012-11-29 | 2013-03-13 | 海昌隐形眼镜有限公司 | Organic silicon hydrogel material of contact lenses and preparation method thereof |
-
2016
- 2016-11-25 CN CN201611054914.1A patent/CN108102047A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102964532A (en) * | 2012-11-29 | 2013-03-13 | 海昌隐形眼镜有限公司 | Organic silicon hydrogel material of contact lenses and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPS58169127A (en) | Contact lens material containing silicon and contact lens made of same | |
| ATE406594T1 (en) | CONTACT LENS | |
| CN102964532A (en) | Organic silicon hydrogel material of contact lenses and preparation method thereof | |
| CN106062043B (en) | Hydrophilic organic silicon composition | |
| CN1119413A (en) | Cosmetic or topical use of an aqueous dispersion based on non-volatile organopolysiloxanes and an acrylamide or homopolymeric copolymer type cross-linked methacryloyloxyethyl trimethylammonium ...... | |
| JPS5977411A (en) | Oxygen permeating hard contact lens | |
| US20170176642A1 (en) | Contact lens material | |
| CN109212777A (en) | Contact lenses with surface modifications and methods of making the same | |
| CN104142581A (en) | Ophthalmic devices with stabilization features | |
| CN108102038A (en) | A kind of hydrogel | |
| CN108102049A (en) | The preparation method of hydrogel | |
| JP6510497B2 (en) | Anionic drug-containing medical device | |
| CN1312067A (en) | Cosmetic composition containing vinyl-dimethyl-polyorganosiloxane/dimethyl-polyorganosiloxane copolymer water milk and thickening agent and use thereof | |
| CN108102047A (en) | Hydrogel | |
| CN106749877B (en) | A kind of high oxygen permeability optical lens material and preparation method thereof | |
| CN108102039A (en) | A kind of preparation method of hydrogel | |
| CN108102037A (en) | A kind of preparation method of hydrophilic hydrogel | |
| CN102675561A (en) | Silicone hydrogel with high water content | |
| CN108642895A (en) | A kind of aqueous coating automobile artificial leather and preparation method thereof | |
| CN104138340B (en) | It is a kind of to be used to be impregnated in more effect cosmetic breasts of sponge material and preparation method thereof | |
| CN203930243U (en) | A kind of novel high oxygen permeability contact lens | |
| TWI612093B (en) | Silicone hydrogel contact lens and method for making same | |
| CN112812243A (en) | Oxygen-permeable fluorosilicone hydrogel contact lens and preparation method thereof | |
| CN104945570B (en) | A kind of Silica hydrogel contact lens and its surface reversion processing method | |
| TWI421306B (en) | Silicone hydrogel with high water content |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20180601 |
|
| WD01 | Invention patent application deemed withdrawn after publication |