CN106749877B - A kind of high oxygen permeability optical lens material and preparation method thereof - Google Patents
A kind of high oxygen permeability optical lens material and preparation method thereof Download PDFInfo
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- CN106749877B CN106749877B CN201611186366.8A CN201611186366A CN106749877B CN 106749877 B CN106749877 B CN 106749877B CN 201611186366 A CN201611186366 A CN 201611186366A CN 106749877 B CN106749877 B CN 106749877B
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
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- C08F220/22—Esters containing halogen
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
- C08F283/12—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polysiloxanes
- C08F283/124—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polysiloxanes on to polysiloxanes having carbon-to-carbon double bonds
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
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Abstract
The invention discloses a kind of high oxygen permeability optical lens materials, the molar percentage of raw material contained by the material and each raw material are as follows: methacryl T- structure siloxanes 1~30%, fluorine-containing methacrylate class monomer 30~60%, methacryl (trimethyl silicane alkoxy) silane 20~40%, hydrophilic monomer 3~15%, the siloxanes 5~30% of methacryl end group, crosslinking agent 1~10%, radical initiator 0.01~0.5%, ultraviolet absorber 0.1~5%.Material of the present invention has the properties such as high oxygen permeability, comfort, wetability, anti-proteinosis.
Description
Technical field
The present invention relates to technical field of polymer materials, more particularly, to a kind of by polymerizable methacryl T- structure
Siloxanes and the preferable monomer copolymerization of other oxygen permeabilities high oxygen permeability optical lens material is made.
Background technique
Gas permeability hard Contact Lens, i.e., usually said RGP (Rigid Gas Permeable) material, i.e.,
" gas permeability hard material ", it is grown up on the basis of PMMA (poly- polymethacrylic acid methyl ester material).Earliest period hard angle
Material used in film contact lense is PMMA, it has good optical property, but completely airtight, and patient can not match for a long time
It wears, in order to improve permeability, in terms of overcoming the shortcomings of PMMA permeability, researcher develops new containing silica gel and fluorine
High oxygen permeability material-RGP, it have biocompatibility, without force characteristic, surface characteristic.
RGP eyeglass is to wear day, and DK is necessarily greater than 18, and the material that moulding mirror should select oxygen flow some higher, DK value is at least
It is greater than 50；Ortho-K piece is larger compared with common RGP eyeglass, it is thick, and more patients can select night to wear, and night wears
The material DK of piece is typically greater than 90, and thickness is less than 0.3mm, to meet security requirement；
Ortho-K is by using special designing, and symmetrically, gradual change Central corneal surface shape lowers
Myopia, the effect that cornea moulding generates is provisional and recoverable, although Ortho-K can help most people to improve view
Power, but it is be more good to the effect within the scope of specific luminosity prescription, cornea hardness, cornea shape, intraocular pressure water including individual
Flat, corneal astigmatism situation and contact lens wear can be suitble to, use the end-to-end of advanced modernization eye examination equipment
It could determine that wearer moulds mirror if appropriate for cornea is worn；Influence Ortho-K wear comfort and effect mainly there are two because
Number: the surface moisture of mirror surface and the hardness of material, if the excessive high hardness of material, wearing cornea modeling mirror can be quite uncomfortable；Such as
The hardness of fruit material is too low, and it is poor to wear effect brought by cornea modeling mirror；If the surface moisture of mirror surface is lower, cornea is worn
Moulding mirror can be quite uncomfortable, can damage cornea；If the surface moisture of mirror surface is higher, wearing cornea modeling mirror can be very comfortable, shadow
Ring effect brought by its oxygen permeability.
Is the necessity of contact lenses oxygen transmission rate measurement at which? it is known that importance of the oxygen to cornea, therefore in people
Selection oxygen permeability preferable product can be inclined to when choosing contact lenses.When the manufacturers of contact lenses publicizes product parameters, just comprising
The OTR oxygen transmission rate coefficient of conductivity, usual optist can be the product that wearer's selection is most suitable for their demands according to this parameter.
Transmitance generally indicates that transmission coefficient is generally described with DK/t with unit DK.Here: D--- material diffusion coefficient, k---- oxygen
Solubility, t---- lens thickness.
Known contact lens material, the absorbability of its oxygen molecule depend on the size of K value, while higher D, material
Diffusivity can also assist in ensuring that oxygen can be quickly through eyeglass.Eyeglass is thicker, and oxygen is interrupted more, therefore permeability meeting
Weaken.
Glasses generally all need to measure using the diffusivity of material.Ultra-thin high transmittance eyeglass usually has preferable saturating
The property crossed, but this does not imply that we only need to select the most thin highest material of transmitance so simple.Every pair contact lens material
The shape and thickness of material have subtle difference, when oxygen permeability coefficient is tested, the eyeglass conduct of our usual diopters -3.00
Standard testing object.The center thickness of eyeglass we it should be appreciated that because this is direct covering pupil region.
The performance of hard contact lens (RGP) optically is even better than common soft contact lens, can preferably protect
Corner protector film.Although initial stage, which wears, might have uncomfortable feeling compared to soft lens, this kind of eyeglass possesses as soft lens
Transmitance, while longer life expectancy save the use cost of wearer.In early stage contact lenses in use, being particularly
From the initial stage eighties, people also gradually recognize oxygen to the importance of cornea.Namely since at that time, Ren Menkai
Begin to formulate relevant international standard.Early stage to have ISO 9913-1:1996 and 9913-2:2000 to teach contact lenses respectively saturating
The test method of oxygen quotient, polarography and coulometry.However the silicone resin eyeglass of some high DK values is difficult precise measurement, therefore new
Standard be modified on the basis of original coulometry.Ultimately form the ISO 18369-4:2006 contact lenses of today
Testing standard.DK/t is used to describe the eyeglass of finished product here unlike standard before, and is no longer substrate.And pass through
The thickness t of eyeglass is measured, unit directly develops into DK value.
The solution of Xi Shidai instrument (Systech Illinois), Systechillinois researched and developed 8003 thoroughly
Oxygen instrument can accurately measure the oxygen permeability coefficient of contact lenses.Oxygen is detected using the sensor of the coulomb electricity principle of its patent
Transmitance, sample has special attachment that can place, is detailed in diagram.99.9% pure oxygen can be passed through epicoele, and cavity of resorption is passed through height
Purity nitrogen N2 after oxygen molecule is permeated by mirror surface, is carried by the High Purity Nitrogen N2 of cavity of resorption to sensor, and directly measure oxygen by sensor
The content of gas, to obtain mirror surface oxygen transit dose.The unit of usual sample oxygen permeating amount is CC/M2/DAY or CC/
100INCH2/DAY.U.S. ILLINOIS8003 contact lenses oxygen flow instrument test scope: 3 × 10-11~4.94 × 10-7cm3/
cm2.s.mmHg, 2 × 10-11~3.7 × 10-7cm3/cm2.s.hPa.Test method: after sample is packed into test chamber, test chamber
It is divided into two parts up and down, the certain test gas of oxygen content is filled in epicoele, carrier gas flows into coulomb sensing after flowing through cavity of resorption
In device, the pressure on sample both sides is equal, but oxygen partial pressure is different, and oxygen enters carrier gas stream through film under concentration difference effect,
It is sent in coulomb sensor, the amount of oxygen carried in nitrogen stream is accurately measured by coulomb sensor, to calculate material
OTR oxygen transmission rate.
It is known that oxygen, to the importance of cornea, DK is that (D is dispersion coefficient to oxygen permeability coefficient, i.e., gas molecule is in object
The speed moved in matter.K is solubility factor, i.e., at a particular pressure, the gas flow that can be dissolved in unit volume substance), it indicates
The oxygen permeability of lens materials, it is unrelated with thickness.The oxygen permeability of evaluation particular optic must take into account lens thickness, DK/L
Value is the actual speed that oxygen passes through certain thickness particular optic, and DK/L value is higher, and the oxygen permeability of eyeglass is better.L refers to eyeglass
Thickness, unit are centimetre.The center thickness of -3.00D eyeglass is usually used when calculating negative eyeglass, is printed on most of lens prescriptions
The center thickness of L value only representative -3.00D eyeglass, unit are millimeters, and when calculating must be converted into centimetre.
It is ensured well in short, the oxygen permeability of strict control contact lens material is one for consumer, at present state
Interior major contact lenses manufacturer gradually starts to pay attention to, we wait in expectation a safer contact lenses production and
Test atmosphere allows consumer to trust safe use.
Summary of the invention
In view of the above-mentioned problems existing in the prior art, the applicant provide a kind of high oxygen permeability optical lens material and its
Preparation method.Material of the present invention has the properties such as high oxygen permeability, comfort, wetability, anti-proteinosis.
Technical scheme is as follows:
A kind of high oxygen permeability optical lens material, the molar percentage of raw material and each raw material contained by the material are as follows:
After above-mentioned raw materials are mixed in proportion, when being evenly stirred until mixed liquor bleach shape liquid, continue to stir, and be passed through
Mixed liquor is transferred in sheet mold by nitrogen at least 30min then under the conditions of nitrogen protection, and is put into constant temperature oven, if
Setting polymerizing condition is to react above to get the high oxygen permeability optical lens material for 24 hours at 60~150 DEG C.
The methacryl T- structure siloxanes is
One of or it is a variety of.
The fluorine-containing methacrylate class monomer is methacrylic acid hexafluoro isopropyl ester, acrylic acid hexafluoro isopropyl
Ester, seven fluorine butyl ester of methacrylic acid, methacrylic acid octafluoro isobutyl ester, acrylic acid octafluoro isobutyl ester, methacrylic acid perfluor
One of Arrcostab, perfluoroalkyl acrylate are a variety of.
The siloxanes of the methacryl end group is
One of or it is a variety of.
The crosslinking agent is
(Alkylene glycol dimethacrylate) wherein, R C1-8Alkyl.
The hydrophilic monomer is one of methacrylic acid, acrylic acid, methacrylic acid -2- hydroxyethyl ester or a variety of.
The ultraviolet absorber is the ultraviolet absorber containing benzophenone or benzotriazole group.
The ultraviolet absorber is 2- [3- (2H- benzotriazole -2- base) -4- hydroxy phenyl] ethyl methacrylate (2-
[3- (2H-Benzotriazol-2-yl) -4-hydroxyphenyl] ethyl methacrylate), acrylic acid (4- benzoyl
Base -3- hydroxyphenoxy) one of ethyl ester (2- (4-Benzoyl-3-hydroxyphenoxy) ethyl acrylate) or
Two kinds of compositions.
The radical initiator is azodiisobutyronitrile, azocyclohexane, benzoyl peroxide, cumyl peroxide
One of or it is a variety of.
The high oxygen permeability optical lens material can be used for preparing nearsighted eyeglass, Ortho-K piece or RGP eyeglass.
The present invention is beneficial to be had the technical effect that
The solvability (i.e. k value) of O2 in the material can be improved in fluorine-containing methacrylate class monomer of the present invention, with dimension
High oxygen permeability energy is held, but also the lipophilic disadvantage of organosilicon material can be made up；Methacryl propyl T- structure siloxanes
T- structure siloxane group be a big branched group, increase the space of reticular structure, to increase the oxygen permeability of material；
Methacryl (trimethyl silicane alkoxy) silane can also be improved the oxygen permeability of material, while part increases its netted knot
The space of structure also partially increases the oxygen permeability of material.
The dimethyl silicone polymer of methacryl propyl end group of the present invention, a kind of crosslinking agent of bigger molecule, one side
Face increases the oxygen permeability of material, while the also hardness of adjustable material；It adjusts material with small molecule crosslinking agent jointly
The hardness of reticular structure and material.
The raw material that the present invention chooses, synergistic effect, common compatibility have final high oxygen permeability optical lens material preferable
The properties such as oxygen permeability, comfort, wetability, anti-proteinosis.
Detailed description of the invention
Fig. 1 is process flow chart of the invention.
Specific embodiment
With reference to the accompanying drawings and examples, the present invention is specifically described.
Embodiment 1
In the three-necked bottle of a round bottom, it is put into 0.273mol methacrylic acid hexafluoro isopropyl ester, 0.112mol methyl
Acryloyl (trimethyl silicane alkoxy) silane, 0.0127mol methacryl T- structure siloxanes (B), 0.004mol methyl-prop
The siloxanes (F) of alkene acyl end group, 0.01mol ethylene glycol dimethacrylate diester, 0.058mol methacrylic acid,
0.0046mol acrylic acid (4- benzoyl -3- hydroxyphenoxy) ethyl ester, 0.001mol azodiisobutyronitrile, stirring to mixing
Liquid bleach liquid, continues to stir, and is passed through nitrogen 50 minutes, and then under the conditions of nitrogen protection, mixed liquor is transferred to piece
In shape mold, and it is put into constant temperature oven, setting polymerizing condition is at 65 DEG C at 8 hours, 90 DEG C 8 hours at 8 hours, 13 DEG C, most
The high oxygen permeability optical lens material is made eventually.
Embodiment 2
In the three-necked bottle of a round bottom, seven fluorine butyl ester of 0.30mol methacrylic acid, 0.13mol metering system is added
Acyl (trimethyl silicane alkoxy) silane, 0.014mol methacryl T- structure siloxanes (A), 0.011mol methacryl end
The siloxanes (E) of base, 0.058mol methacrylic acid, 0.003mol acrylic acid (4- benzoyl -3- hydroxyphenoxy) ethyl ester,
0.001mol azodiisobutyronitrile, 0.056mol ethylene glycol dimethacrylate diester, stirring to mixed liquor bleach liquid, after
Continuous stirring, and it is passed through nitrogen 60 minutes, then under the conditions of nitrogen protection, mixed liquor is transferred in sheet mold, and is put into
Constant temperature oven, setting polymerizing condition be at 60 DEG C at 8 hours, 85 DEG C 8 hours at 8 hours, 120 DEG C be finally made it is described it is high thoroughly
Oxygen optical lens material.
Embodiment 3
In the three-necked bottle of a round bottom, 0.47mol methacrylic acid hexafluoro isopropyl ester, 0.24mol methyl-prop is added
Alkene acyl (trimethyl silicane alkoxy) silane, 0.034mol methacryl T- structure siloxanes (C), 0.048mol methacryl
The siloxanes (E) of end group, 0.12mol methacrylic acid, 0.003mol 2- [3- (2H- benzotriazole -2- base) -4- hydroxy benzenes
Base] ethyl methacrylate, 0.002mol azodiisobutyronitrile, stir to mixed liquor bleach liquid, continue to stir, and be passed through
Nitrogen 60 minutes, then under the conditions of nitrogen protection, mixed liquor is transferred in sheet mold, and be put into constant temperature oven, is arranged
Polymerizing condition be 75 DEG C at 12 hours at 12 hours, 130 DEG C, the high oxygen permeability optical lens material is finally made.
Embodiment 4
In the three-necked bottle of a round bottom, 0.49mol methacrylic acid hexafluoro isopropyl ester, 0.24mol methyl-prop is added
Alkene acyl (trimethyl silicane alkoxy) silane, 0.034mol methacryl T- structure siloxanes (D), 0.048mol methacryl
The siloxanes (F) of end group, 0.051mol ethylene glycol dimethacrylate diester, 0.12mol methacrylic acid, 0.0062mol third
Olefin(e) acid (4- benzoyl -3- hydroxyphenoxy) ethyl ester, 0.002mol azodiisobutyronitrile, stirring to mixed liquor bleach liquid
Body continues to stir, and is passed through nitrogen 80 minutes, and then under the conditions of nitrogen protection, mixed liquor is transferred in sheet mold, and
It is put into constant temperature oven, setting polymerizing condition is at 60 DEG C at 8 hours, 85 DEG C 8 hours at 8 hours, 120 DEG C, final to be made described
High oxygen permeability optical lens material.
Embodiment 5
In the three-necked bottle of a round bottom, 0.49mol methacrylic acid hexafluoro isopropyl ester, 0.24mol methyl-prop is added
Alkene acyl (trimethyl silicane alkoxy) silane, 0.034mol methacryl T- structure siloxanes (B), 0.048mol methacryl
The siloxanes (E) of end group, 0.02mol ethylene glycol dimethacrylate diester, bis- (the 3- methacryls) four-(three of 0.009mol
Methyl) disiloxane, 0.062mol methacrylic acid -2- hydroxyethyl ester, 0.093mol methacrylic acid, 0.0062mol 2-
[3- (2H- benzotriazole -2- base) -4- hydroxy phenyl] ethyl methacrylate, 0.002mol azodiisobutyronitrile are stirred to mixed
Liquid bleach liquid is closed, continues to stir, and be passed through nitrogen 50 minutes, then under the conditions of nitrogen protection, mixed liquor is transferred to
In sheet mold, and it being put into constant temperature oven, setting polymerizing condition is at 75 DEG C at 8 hours, 95 DEG C 8 hours at 8 hours, 140 DEG C,
The high oxygen permeability optical lens material is finally made.
The high oxygen permeability optical lens material is made it is 11.0 inches long and wide, with a thickness of 4.5 millimeters of flaky material,
And flaky material is cut into round coarse-grain piece, the extractable matter in coarse-grain piece is removed by extraction, then drying has extracted
Coarse-grain piece finally tests coarse crystal blank.Test result is as shown in table 1.
Embodiment 6
In the three-necked bottle of a round bottom, 0.49mol methacrylic acid hexafluoro isopropyl ester, 0.24mol methyl-prop is added
Alkene acyl (trimethyl silicane alkoxy) silane, 0.034mol methacryl T- structure siloxanes (A), 0.048mol methacryl
The siloxanes (F) of end group, 0.02mol ethylene glycol dimethacrylate diester, bis- (the 3- methacryls) four-(three of 0.026mol
Methyl) disiloxane, 0.062mol methacrylic acid -2- hydroxyethyl ester, 0.093mol methacrylic acid, 0.0062mol2- [3-
(2H- benzotriazole -2- base) -4- hydroxy phenyl] ethyl methacrylate, 0.002mol azodiisobutyronitrile, stirring to mixing
Liquid bleach liquid, continues to stir, and is passed through nitrogen 80 minutes, and then under the conditions of nitrogen protection, mixed liquor is transferred to piece
In shape mold, and it is put into constant temperature oven, setting polymerizing condition is at 60 DEG C at 8 hours, 85 DEG C 8 hours at 8 hours, 120 DEG C, most
The high oxygen permeability optical lens material is made eventually.
Test case:
(1) by high oxygen permeability optical lens material made from Examples 1 to 6 be respectively prepared it is long and it is wide be 11.0 inches,
With a thickness of 4.5 millimeters of flaky material, and flaky material is cut into round coarse-grain piece, by extraction remove coarse-grain piece in can
Extract, then the dry coarse-grain piece extracted, is made coarse crystal blank and is tested (GB11417) it.Test result
As shown in table 1.
Table 1
(2) anti-proteinosis test
By the resulting high oxygen permeability optical lens material of Examples 1 to 6 be respectively prepared it is long and it is wide be 11.0 inches, thickness
For 4.5 millimeters of flaky material, and flaky material is cut into round coarse-grain piece, passes through extraction and remove extracting in coarse-grain piece
Object, then the dry coarse-grain piece extracted, is made coarse crystal blank, finally by coarse crystal blank in the PBS solution that pH is 7.4
It impregnates for 24 hours, then moves into 10ml bovine serum albumen solution (protein concentration 4.00mg/ml), 37 DEG C are placed for 24 hours, surface
The material for having adsorbed protein rinses three times in the PBS solution of pH7.4, and 10 minutes every time, to remove the unadsorbed albumen in surface
Then coarse crystal blank is immersed in solution of the 10ml containing 1%SDS by matter, shake 4h, make the egg of coarse crystal blank adsorption
White matter completely falls off into solution.
Absorbance of the solution at 570nm is tested in microplate reader, Proteins In Aqueous Solutions concentration is calculated according to standard curve,
The amount of coarse crystal blank adsorption protein is learnt into calculating.The results are shown in Table 2.
Table 2
| Protein adsorbance/(μ g/cm2) | |
| Embodiment 1 | 15 |
| Embodiment 2 | 13 |
| Embodiment 3 | 18 |
| Embodiment 4 | 20 |
| Embodiment 5 | 12 |
| Embodiment 6 | 15 |
(3) swelling ratio is tested
By high oxygen permeability optical lens material made from Examples 1 to 6 be respectively prepared it is long and it is wide be 11.0 inches, thickness
For 4.5 millimeters of flaky material, and flaky material is cut into round coarse-grain piece, passes through extraction and remove extracting in coarse-grain piece
Object, then the dry coarse-grain piece extracted, is made coarse crystal blank, and its room temperature is placed in physiological saline 48h, inhales it sufficiently
Then water dips in the Free water of blank surface with absorbent cotton, weighs blank weight in wet base to being saturated；Then wet hair base vacuum is placed in dry
Dry in case, the weight after weighing dehydration calculates swelling ratio, i.e. swelling ratio=(weight in wet base-dry weight)/dry weight * 100%.
Table 3
| Swelling ratio/% | |
| Embodiment 1 | 5 |
| Embodiment 2 | 3 |
| Embodiment 3 | 6 |
| Embodiment 4 | 5 |
| Embodiment 5 | 4 |
| Embodiment 6 | 6 |
Claims (7)
1. a kind of high oxygen permeability optical lens material, it is characterised in that the molar percentage of raw material contained by the material and each raw material
Are as follows:
After above-mentioned raw materials are mixed in proportion, when being evenly stirred until mixed liquor bleach shape liquid, continue to stir, and be passed through nitrogen
Mixed liquor is transferred in sheet mold by least 30min then under the conditions of nitrogen protection, and is put into constant temperature oven, and setting is poly-
Conjunction condition is to react above to get the high oxygen permeability optical lens material for 24 hours at 60~150 DEG C；
The methacryl T- structure siloxanes is
M be 1~20 integer,
M be the integer that 1~20, n is 1~20,
M be 1~100 integer,
M is the integer that 1~100, n is 1~50
One of or it is a variety of；
The fluorine-containing methacrylate class monomer is methacrylic acid hexafluoro isopropyl ester, acrylic acid hexafluoro isopropyl ester, first
Seven fluorine butyl ester of base acrylic acid, methacrylic acid octafluoro isobutyl ester, acrylic acid octafluoro isobutyl ester, methacrylic acid perfluoroalkyl
One of ester, perfluoroalkyl acrylate are a variety of；
The siloxanes of the methacryl end group is
M be 1~100 integer,
M be the integer that 1~100, n is 1~50,
One of or it is a variety of.
2. high oxygen permeability optical lens material according to claim 1, it is characterised in that the crosslinking agent is
Wherein, R C1-8Alkyl.
3. high oxygen permeability optical lens material according to claim 1, it is characterised in that the hydrophilic monomer is methyl-prop
One of olefin(e) acid, acrylic acid, methacrylic acid -2- hydroxyethyl ester are a variety of.
4. high oxygen permeability optical lens material according to claim 1, it is characterised in that the ultraviolet absorber be containing
The ultraviolet absorber of benzophenone or benzotriazole group.
5. high oxygen permeability optical lens material according to claim 4, it is characterised in that the ultraviolet absorber is 2- [3-
(2H- benzotriazole -2- base) -4- hydroxy phenyl] ethyl methacrylate, acrylic acid (4- benzoyl -3- hydroxyphenoxy)
One or both of ethyl ester composition.
6. high oxygen permeability optical lens material according to claim 1, it is characterised in that the radical initiator is even
One of nitrogen bis-isobutyronitrile, azocyclohexane, benzoyl peroxide, cumyl peroxide are a variety of.
7. the application of high oxygen permeability optical lens material described in a kind of claim 1, it is characterised in that the material can be used for making
Standby nearsighted eyeglass, Ortho-K piece or RGP eyeglass.
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| ES2934410T3 (en) * | 2018-06-28 | 2023-02-21 | Acuity Polymers Inc | Material with ultra-high Dk |
| CN114516942A (en) * | 2020-11-18 | 2022-05-20 | 亨泰光学股份有限公司 | Hard oxygen-permeable contact lens polymer material and polymerization method thereof |
| CN114516941A (en) * | 2020-11-18 | 2022-05-20 | 亨泰光学股份有限公司 | Polymerization method of hard oxygen permeable contact lens polymer material |
| CN113698552A (en) * | 2021-09-06 | 2021-11-26 | 无锡蕾明视康科技有限公司 | High-oxygen-permeability polyacrylate material and preparation method and application thereof |
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| CN1537249A (en) * | 2001-10-09 | 2004-10-13 | 可乐丽股份有限公司 | Oxygen-permeable hard contact lens |
| US8133960B2 (en) * | 2009-06-16 | 2012-03-13 | Bausch & Lomb Incorporated | Biomedical devices |
| CN102675561B (en) * | 2011-03-07 | 2014-10-22 | 远东新世纪股份有限公司 | silicone hydrogel with high water content |
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