CN108079192A - 一种治疗慢性胆囊炎的药剂的制备方法 - Google Patents
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Abstract
本发明涉及一种治疗慢性胆囊炎的药剂的制备方法，该方法包括下列步骤：取八楞木60克、三爪金龙50克、墙草根50克、石壁莲50克、八宝茶45克、天青地白40克、山花生40克、飞蛾树30克、水蔓青30克、红门兰30克、芙蓉花35克、卤地菊35克、泥胡菜35克、四照花30克和甘草20克，加入水15000毫升，在装有冷凝器的烧瓶中在90℃下加热6小时，过滤，滤液即得。本发明所述的治疗慢性胆囊炎的药剂组成合理，效果明确，十分适于在临床上大规模推广。
Description
技术领域
本发明涉及医药领域，具体来说涉及一种治疗慢性胆囊炎的药剂的制备方法。
背景技术
慢性胆囊炎是较常见的胆囊疾病，发病率较高。常与胆石症合并存在。但也有一些为非结石性的慢性胆囊炎，慢性胆囊炎常见治疗方法有：药物治疗和手术治疗。行胆囊切除术是慢性胆囊炎的根本治疗，但是手术治疗创伤大，有心、肝、肺等严重疾病或全身情况不能耐受手术，不可以进行手术的治疗。西药治疗对肝、胃等身体其它器官损伤大。目前临床多发，需要新的治疗药物。
发明内容
本发明的目的是提供一种治疗慢性胆囊炎的药剂的制备方法。
为了实现本发明的目的，本发明提供一种治疗慢性胆囊炎的药剂的制备方法，该方法包括下列步骤：取八楞木60克、三爪金龙50克、墙草根50克、石壁莲50克、八宝茶45克、天青地白40克、山花生40克、飞蛾树30克、水蔓青30克、红门兰30克、芙蓉花35克、
卤地菊35克、泥胡菜35克、四照花30克和甘草20克，加入水15000毫升，在装有冷凝器的烧瓶中在90℃下加热6小时，过滤，滤液即得。
本发明还提供组合物在制备治疗慢性胆囊炎的荮剂中的用途，它是由下列原料药按重量份计制成：八楞木60份、三爪金龙50份、墙草根50份、石壁莲50份、八宝茶45份、天青地白40份、山花生40份、飞蛾树30份、水蔓青30份、红门兰30份、芙蓉花35份、卤地菊35份、泥胡菜35份、四照花30份和甘草20份。
优选地，所述药剂可以是片剂、分散片、崩解片、速溶片、肠溶片、胶囊剂或汤剂。
在本发明的组合物中，八楞木、三爪金龙为君药，墙草根、石壁莲、八宝茶、天青地白、山花生为臣药，飞蛾树、水蔓青、红门兰、芙蓉花、卤地菊、泥胡菜、四照花为佐药，甘草调和诸药，为使药。各种成分发挥协同作用以产生最佳效果。
本发明所述的治疗慢性胆囊炎的药剂组成合理，效果明确，十分适于在临床上大规模推广。
具体实施方式
下面通过实施例进一步说明本发明。应该理解的是，本发明的实施例是用于说明本发明而不是对本发明的限制。根据本发明的实质对本发明进行的简单改进都属于本发明要求保护的范围。除非另有说明，否则本发明中的百分数是重量百分数。
实施例本发明的汤剂
取八楞木60克、三爪金龙50克、墙草根50克、石壁莲50克、八室茶45克、天青地白40克、山花生40克、飞蛾树30克、水蔓青30克、红门兰30克、芙蓉花35克、卤地菊35克、泥胡菜35克、四照花30克和甘草20克，加入水15000毫升，在装有冷凝器的烧瓶中在90℃下加热6小时，过滤，滤液即得。
实验例
诊断标准。
参照卫生部《中药新药临床研究指导原则》拟定：①持续性右上腹隐痛或不适感，疼痛可向右背肩部放射；②有恶心、嗳气、反酸、腹胀和胃部灼热等消化不良症状，进食油腻食物后加重，而且病程长，病情经过有急性发作和缓解交替的特点；③胆囊区触痛明显，右上腹肌紧张，莫非氏征阳性；④B超可见胆囊壁增厚，胆囊缩小或变形，胆囊收缩功能不良，或胆囊显影淡薄等。
选择符合上述标准的患者150例，其中女性80例，男性70例，年龄29-58岁，平均41岁。
使用实施例中制得的汤剂来进行治疗，一天两次，每次口服150毫升，连续治疗50天。
疗效判定标准
①治愈：临床症状体征消失，B超检查或胆囊造影恢复正常，观察半年无复发；②显效：症状体征基本消失，B超检查或胆囊造影明显改变；③无效：治疗期间症状和体征减轻或无改善，停止治疗后又复发。
结果
经过治疗，发现全部患者临床症状体征消失，B超检查或胆囊造影恢复正常，在治疗之后观察半年无复发，因此全部符合治愈的疗效判定标准。
舆型病例
李某，女，42岁，政府公务员，患者右肋部胀痛，恶心欲吐1月，伴腹胀咯气，大便质粘不爽，每日一次(无粘液、脓血)。B超检查：胆囊7.7cm×3.8cm，壁厚0.9cm，囊内模糊。
使用实施例中制得的汤剂来进行治疗，一天两次，每次口服150毫升，连续治疗50天。经过治疗后，患者临床症状体征消失，B超检查或胆囊造影恢复正常，在治疗之后观察半年无复发。
Claims (3)
1.一种治疗慢性胆囊炎的药剂的制备方法，该方法包括下列步骤：取八楞木60克、三爪金龙50克、墙草根50克、石壁莲50克、八宝茶45克、天青地白40克、山花生40克、飞蛾树30克、水蔓青30克、红门兰30克、芙蓉花35克、卤地菊35克、泥胡菜35克、四照花30克和甘草20克，加入水15000毫升，在装有冷凝器的烧瓶中在90℃下加热6小时，过滤，滤液即得。
2.组合物在制备治疗慢性胆囊炎的药剂中的用途，其特征在于，它是由下列原料药按重量份计制成：八楞木60份、三爪金龙50份、墙草根50份、石壁莲50份、八宝茶45份、天青地白40份、山花生40份、飞蛾树30份、水蔓青30份、红门兰30份、芙蓉花35份、卤地菊35份、泥胡菜35份、四照花30份和甘草20份。
3.根据权利要求2所述的用途，其特征在于，所述药剂可以是片剂、分散片、崩解片、速溶片、肠溶片、胶囊剂或汤剂。
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Application publication date: 20180529 |