CN108078810A - The skin care cosmetic composition of Whitening, spot - Google Patents
The skin care cosmetic composition of Whitening, spot Download PDFInfo
- Publication number
- CN108078810A CN108078810A CN201711366173.5A CN201711366173A CN108078810A CN 108078810 A CN108078810 A CN 108078810A CN 201711366173 A CN201711366173 A CN 201711366173A CN 108078810 A CN108078810 A CN 108078810A
- Authority
- CN
- China
- Prior art keywords
- parts
- spot
- whitening
- skin care
- cosmetic composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of skin care cosmetic compositions of Whitening, spot, are prepared by following raw materials：0.4 4 parts of Troxerutin, 0.5 5 parts of papain, 1 10 parts of glycerine, 1 10 parts of 1,3 propylene glycol, 0.5 1.5 parts of serine, 5 15 parts of caprylic/capric triglyceride, 15 parts of cetostearyl alcohol, 13 parts of dimethyl silicone polymer, 0.1 1 parts of Phenoxyethanol, 0.1 0.5 parts of EDETATE SODIUM, 10 20 parts of surfactant, 0.01 0.1 parts of bacteriostatic agent, 50 60 parts of water.The skin care cosmetic composition of Whitening, spot of the present invention is with the addition of the excellent skin whitening that reached of Troxerutin, serine and papain, desalinates spot, the effect of bright color.
Description
Technical field
The present invention relates to cosmetic technical fields, and in particular to a kind of skin care cosmetic composition of Whitening, spot.
Background technology
The 5-15% of skin total weight percentage of liveweight, the gross area are 1.5-2 square metres, and skin covering whole body, skin has two
The barrier action of a aspect：On the one hand the loss of internal water, electrolyte and other substances is prevented；On the other hand the external world is prevented to have
The intrusion of evil substance.The stabilization of human internal environment is remain, is physiologically playing important defencive function, while skin also assists in
The metabolic process of human body.If it is desired to possessing the beautiful skin of health, the habits and customs except to form health will also properly protect
Maintenance work particularly with usually exposed skin, such as face, neck, hand, arm, more will be takeed good care of carefully.With ring
Gradual increase of the factors such as border, season to skin effects, people increasingly pay attention to the protection to skin, especially to it is exposed outside
Skin protection, good skin can not only promote the confidence of people, while can make one to obtain in social life more
Favor.
At present, there are many product in the market for beauty, skin care, mainly including products such as anti-aging, beauty treatment, whitenings.This
A little products by environmental change and industrial pollution for being influenced caused skin aging, cortex aging, colour-darkening, tarnish
Deng with improvement result.However, most of in these products is all chemicals, it is water-soluble poor, it is therefore desirable to a large amount of or long
Phase uses, and could really effectively achieve whitening anti-aging effect, and due to being chemicals, a large amount of or long-time service certainly will
Larger side effect can be brought, price is also expensive, it is difficult to reach the target treated both principal and secondary aspect of disease.
The content of the invention
For above-mentioned deficiency in the prior art, the first technical problem to be solved by the present invention is to provide a kind of U.S.
The skin care cosmetic composition of white light spot.
The two of the technical issues of solution of the present invention are to provide a kind of skin care cosmetic composition of Whitening, spot
Preparation method.
The present invention seeks to what is be achieved through the following technical solutions：
A kind of skin care cosmetic composition of Whitening, spot, is prepared by the raw material of following weight parts：Qu Kelu
0.4-4 parts of fourth, 0.5-5 parts of papain, 1-10 parts of glycerine, 1-10 parts of 1,3- propylene glycol, 0.5-1.5 parts of serine, octanoic acid/
5-15 parts of Triglyceride DDD, 1-5 parts of cetostearyl alcohol, 1-3 parts of dimethyl silicone polymer, 0.1-1 parts of Phenoxyethanol, EDTA bis-
0.1-0.5 parts of sodium, 10-20 parts of surfactant, 0.01-0.1 parts of bacteriostatic agent, 50-60 parts of water.
Preferably, the surfactant is wool isopropyl propionate, one in isopropyl stearate, isopropyl myristate
Kind or a variety of mixtures.
It is highly preferred that the surfactant is mixed by wool isopropyl propionate, isopropyl stearate, isopropyl myristate
It closes, the wool isopropyl propionate, isopropyl stearate, the mass ratio of isopropyl myristate are (1-3)：(1-3)：(1-
3)。
Preferably, the bacteriostatic agent is mixtures one or more in galuteolin, ursin, astragalin.
It is highly preferred that the bacteriostatic agent is mixed by galuteolin, ursin, astragalin, the galuteolin,
Ursin, the mass ratio of astragalin are (1-3)：(1-3)：(1-3).
Specifically, in the present invention：
Wool isopropyl propionate, also known as：Isopropyl lanolate, No. CAS：63393-93-1.
Isopropyl stearate, No. CAS：112-10-7.
Isopropyl myristate, No. CAS：110-27-0.
Galuteolin, No. CAS：5373-11-5.
Ursin, No. CAS：497-76-7.
Astragalin, No. CAS：480-10-4.
Troxerutin, No. CAS：7085-55-4 uses Xi'an Jim Press bioengineering Co., Ltd in the embodiment of the present invention
The Troxerutin of offer.
Papain, No. CAS：9001-73-4, it is limited using Nanning Dong Henghua roads biotechnology in the embodiment of the present invention
The cosmetics-stage papain that responsible company provides, enzyme activity are 400,000 u/g.
Glycerine, No. CAS：56-81-5.
Serine, i.e. Serine, No. CAS：56-45-1.
Caprylic/capric triglyceride, No. CAS：65381-09-1.
Cetostearyl alcohol, No. CAS：67762-27-0 is provided using German BASF (former section is peaceful) in the embodiment of the present invention
LanetteD cetostearyl alcohols.
Dimethyl silicone polymer, No. CAS：63148-62-9 uses Ba Tai chemical industry limited public affairs in Guangzhou in the embodiment of the present invention
The dimethyl silicone polymer of the model BT200-350cs provided is provided.
Phenoxyethanol, i.e. ethylene glycol phenyl ether, No. CAS：122-99-6.
EDETATE SODIUM, i.e. disodium ethylene diamine tetraacetate, No. CAS：139-33-3.
1,3-PD, No. CAS：504-63-2.
The skin care cosmetic composition of Whitening, spot of the present invention is with the addition of Troxerutin, serine and Papain
Enzyme has reached excellent skin whitening, desalinates spot, the effect of bright color.
Specific embodiment
With reference to embodiment, the present invention is described further, as described below, is only the preferable implementation to the present invention
Example, not limits the present invention, any person skilled in the art is possibly also with the disclosure above
Technology contents be changed to the equivalent embodiment changed on an equal basis.It is every without departing from the present invention program content, according to the present invention
Any simple modification for being made to following embodiment of technical spirit or equivalent variations, all fall in protection scope of the present invention.
Embodiment 1
The skin care cosmetic composition raw material (parts by weight) of Whitening, spot：2 parts of Troxerutin, 3 parts of papain,
6 parts of glycerine, 4 parts of 1,3- propylene glycol, 1 part of serine, 10 parts of caprylic/capric triglyceride, 3 parts of cetostearyl alcohol, poly dimethyl
1.5 parts of siloxanes, 0.4 part of Phenoxyethanol, 0.2 part of EDETATE SODIUM, 15 parts of surfactant, 0.21 part of bacteriostatic agent, 55 parts of water.
The surfactant is in mass ratio by wool isopropyl propionate, isopropyl stearate, isopropyl myristate
1：1：1 is uniformly mixed to obtain.
The bacteriostatic agent is 1 in mass ratio by galuteolin, ursin, astragalin：1：1 is uniformly mixed
It arrives.
The preparation method of the skin care cosmetic composition of above-mentioned Whitening, spot, comprises the following steps：
(1) homogeneous emulsifying machine (model provided using Guangzhou joint automated machine Science and Technology Ltd. is provided
For the vacuum homogeneous emulsifying machine of VME-300L) water phase pot in, add in EDETATE SODIUM, 1,3-PD, glycerine is with 400 revs/min
Stirring 15 minutes, is heated to 75 DEG C, obtains water and mutually expect；
(2) by caprylic/capric triglyceride, cetostearyl alcohol, dimethyl silicone polymer, Phenoxyethanol, surfactant,
Bacteriostatic agent sequentially adds homogeneous emulsifying machine (the model VME- provided using Guangzhou joint automated machine Science and Technology Ltd.
The vacuum homogeneous emulsifying machine of 300L) oil phase pot in, be heated to 75 DEG C, with 400 revs/min stirring 15 minutes be uniformly mixed, obtain
Oil phase material；
(3) 75 DEG C of water is mutually expected to be pumped into homogeneous emulsifying machine (using Guangzhou joint automated machine Science and Technology Ltd.
The vacuum homogeneous emulsifying machine of the model VME-300L of offer) emulsification pot in, stir and 75 DEG C of oil phase material be pumped under homogeneous,
Then homogeneous 6 minutes at 75 DEG C keep the temperature 20 minutes at 75 DEG C；Then be cooled to 35 DEG C, add in Troxerutin, papain,
It is uniformly mixed within 20 minutes with 400 revs/min of stirrings after serine.Obtain the skin care cosmetics group of the Whitening, spot of embodiment 1
Close object.
Embodiment 2
It is substantially the same manner as Example 1, it differs only in：The bacteriostatic agent by ursin, astragalin in mass ratio
For 1：1 is uniformly mixed to obtain.Obtain the skin care cosmetic composition of the Whitening, spot of embodiment 2.
Embodiment 3
It is substantially the same manner as Example 1, it differs only in：The bacteriostatic agent presses quality by galuteolin, astragalin
Than for 1：1 is uniformly mixed to obtain.Obtain the skin care cosmetic composition of the Whitening, spot of embodiment 3.
Embodiment 4
It is substantially the same manner as Example 1, it differs only in：The bacteriostatic agent by galuteolin, ursin in mass ratio
For 1：1 is uniformly mixed to obtain.Obtain the skin care cosmetic composition of the Whitening, spot of embodiment 4.
Embodiment 5
It is substantially the same manner as Example 1, it differs only in：The surfactant is by isopropyl stearate, nutmeg
Isopropyl propionate is 1 in mass ratio：1 is uniformly mixed to obtain.Obtain the skin care cosmetics group of the Whitening, spot of embodiment 5
Close object.
Embodiment 6
It is substantially the same manner as Example 1, it differs only in：The surfactant is by wool isopropyl propionate, nutmeg
Isopropyl propionate is 1 in mass ratio：1 is uniformly mixed to obtain.Obtain the skin care cosmetics group of the Whitening, spot of embodiment 6
Close object.
Embodiment 7
It is substantially the same manner as Example 1, it differs only in：The surfactant is by wool isopropyl propionate, stearic acid
Isopropyl ester is 1 in mass ratio：1 is uniformly mixed to obtain.Obtain the skin care cosmetics combination of the Whitening, spot of embodiment 7
Object.
Test case 1
Keratoderma hydration rate is tested：Operation principle is using capacitor as instrument probe, since water is medium on skin
The substance of constant maximum, when skin moisture content changes, the capacitance of skin also changes, it is possible to pass through survey
Determine skin pricktest capacitance, analyzing skin surface moisture content.Instrument used is CorneometerCM825.By measuring using production
Before and after product the variation of water content of stratum corneum is weighed in the variation of keratoderma capacitance, so as to evaluate the skin of Whitening, spot
Such method of moisture-keeping efficacy for nursing cosmetic composition carries out quantification to the moisture of keratoderma, can be delicately
The variation of skin moisture content, and favorable reproducibility are reacted, is that skin care cosmetic composition effect of current Whitening, spot is commented
One of common method of valency.
Experimental method：Side, which is bent, in candidate or so forearm marks 3 × 3cm2The square Experimental Area of size, is made with left arm
For the test zone of moisturizer, the uniform skin care cosmetic composition 0.1g for smearing Whitening, spot every square centimeter, right arm
Corresponding symmetrical region is blank control, and the moisture that each experiment position is then detected with CorneometerCM825 tests contains
Amount, is repeated 5 times, draws average value respectively.With formula (1) calculated hydration rate.
The formula (1) of hydration rate=(test value-blank value)/blank value × 100%
The detection of moistening effect, the results are shown in Table 1：
Table 1：Moistening effect test result table
| Time | 1 it is small when | 4 it is small when | 8 it is small when |
| Embodiment 1 | 92 | 67 | 63 |
| Embodiment 2 | 85 | 55 | 50 |
| Embodiment 3 | 87 | 57 | 53 |
| Embodiment 4 | 84 | 54 | 49 |
| Embodiment 5 | 81 | 50 | 41 |
| Embodiment 6 | 82 | 53 | 46 |
| Embodiment 7 | 81 | 51 | 44 |
Comparing embodiment 1 and embodiment 2-4, embodiment 1 (galuteolin, ursin, astragalin compounding) moistening effect
It is substantially better than embodiment 2-4 (both arbitrary compounding in galuteolin, ursin, astragalin)；Comparing embodiment 1 and embodiment
5-7, embodiment 1 (wool isopropyl propionate, isopropyl stearate, isopropyl myristate compounding) moistening effect are substantially better than implementation
Example 5-7 (both arbitrary compounding in wool isopropyl propionate, isopropyl stearate, isopropyl myristate).
Test case 2
By the skin care cosmetic composition of Whitening, spot made from embodiment 1-7, respectively with dark brown vial into
Row is filling, opens wide bottle cap, is placed in preservation 90 days under 40 DEG C of environment temperature, 85% environment of relative humidity, then carries out golden yellow Portugal
Grape coccus (ATCC6538) total plate count is tested, and is surveyed with reference to GBT4789.2-2008 microbiological test of food hygiene total plate count
It is fixed.Specific test result is shown in Table 2.
Table 2：Total plate count tests table
| S. aureus colonies sum, cfu/g | |
| Embodiment 1 | 227 |
| Embodiment 2 | 783 |
| Embodiment 3 | 826 |
| Embodiment 4 | 872 |
| Embodiment 5 | 549 |
| Embodiment 6 | 613 |
| Embodiment 7 | 597 |
Comparing embodiment 1 and embodiment 2-4, embodiment 1 (galuteolin, ursin, astragalin compounding) antiseptic property
It is substantially better than embodiment 2-4 (both arbitrary compounding in galuteolin, ursin, astragalin)；Comparing embodiment 1 and embodiment
5-7, embodiment 1 (wool isopropyl propionate, isopropyl stearate, isopropyl myristate compounding) antiseptic property are substantially better than implementation
Example 5-7 (both arbitrary compounding in wool isopropyl propionate, isopropyl stearate, isopropyl myristate).
Claims (5)
1. a kind of skin care cosmetic composition of Whitening, spot, which is characterized in that by the raw material preparation of following weight parts
Into：0.4-4 parts of Troxerutin, 0.5-5 parts of papain, 1-10 parts of glycerine, 1-10 parts of 1,3- propylene glycol, serine 0.5-
1.5 parts, 5-15 parts of caprylic/capric triglyceride, 1-5 parts of cetostearyl alcohol, 1-3 parts of dimethyl silicone polymer, Phenoxyethanol
0.1-1 parts, 0.1-0.5 parts of EDETATE SODIUM, 10-20 parts of surfactant, 0.01-0.1 parts of bacteriostatic agent, 50-60 parts of water.
2. the skin care cosmetic composition of Whitening, spot as described in claim 1, it is characterised in that：It lives on the surface
Property agent be wool isopropyl propionate, isopropyl stearate, mixtures one or more in isopropyl myristate.
3. the skin care cosmetic composition of Whitening, spot as claimed in claim 2, it is characterised in that：It lives on the surface
Property agent is mixed by wool isopropyl propionate, isopropyl stearate, isopropyl myristate, the wool isopropyl propionate, tristearin
Isopropyl propionate, the mass ratio of isopropyl myristate are（1-3）：（1-3）：（1-3）.
4. the skin care cosmetic composition of the Whitening, spot as any one of claim 1-3, it is characterised in that：Institute
The mixture that the bacteriostatic agent stated is galuteolin, one or more in ursin, astragalin.
5. the skin care cosmetic composition of Whitening, spot as claimed in claim 4, it is characterised in that：The bacteriostatic agent
It is mixed by galuteolin, ursin, astragalin, the galuteolin, ursin, the mass ratio of astragalin are（1-
3）：（1-3）：（1-3）.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711366173.5A CN108078810A (en) | 2017-12-18 | 2017-12-18 | The skin care cosmetic composition of Whitening, spot |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711366173.5A CN108078810A (en) | 2017-12-18 | 2017-12-18 | The skin care cosmetic composition of Whitening, spot |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108078810A true CN108078810A (en) | 2018-05-29 |
Family
ID=62177059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711366173.5A Pending CN108078810A (en) | 2017-12-18 | 2017-12-18 | The skin care cosmetic composition of Whitening, spot |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108078810A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108524316A (en) * | 2018-07-18 | 2018-09-14 | 张永 | A kind of Whitening, spot composition and preparation method thereof |
| CN110964070A (en) * | 2019-12-05 | 2020-04-07 | 广州汀兰生物科技有限公司 | Preparation method of troxerutin and application of troxerutin in whitening and skin-care products |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030206932A1 (en) * | 1994-09-07 | 2003-11-06 | Jue-Chen Liu | Novel topical compositions |
| CN103442567A (en) * | 2011-03-23 | 2013-12-11 | 巴斯夫欧洲公司 | Compositions containing polymeric, ionic compounds comprising imidazolium groups |
| CN105030586A (en) * | 2015-07-07 | 2015-11-11 | 海南海润生物科技股份有限公司 | Whitening spot-fading cosmetic containing marine active peptide and preparation method thereof |
| CN105168055A (en) * | 2015-09-19 | 2015-12-23 | 浙江大学 | Skin whitening and spot banishing cosmetic containing sweet osmanthus phenylethanoid glycosides and preparation method of skin whitening and spot banishing cosmetic |
| CN105193641A (en) * | 2015-11-03 | 2015-12-30 | 广州市高姿化妆品有限公司 | Skin whitening and fleck removing skin-care composition |
-
2017
- 2017-12-18 CN CN201711366173.5A patent/CN108078810A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030206932A1 (en) * | 1994-09-07 | 2003-11-06 | Jue-Chen Liu | Novel topical compositions |
| CN103442567A (en) * | 2011-03-23 | 2013-12-11 | 巴斯夫欧洲公司 | Compositions containing polymeric, ionic compounds comprising imidazolium groups |
| CN105030586A (en) * | 2015-07-07 | 2015-11-11 | 海南海润生物科技股份有限公司 | Whitening spot-fading cosmetic containing marine active peptide and preparation method thereof |
| CN105168055A (en) * | 2015-09-19 | 2015-12-23 | 浙江大学 | Skin whitening and spot banishing cosmetic containing sweet osmanthus phenylethanoid glycosides and preparation method of skin whitening and spot banishing cosmetic |
| CN105193641A (en) * | 2015-11-03 | 2015-12-30 | 广州市高姿化妆品有限公司 | Skin whitening and fleck removing skin-care composition |
Non-Patent Citations (8)
| Title |
|---|
| 俞志明: "《中国化工商品大全》", 31 March 1996, 中国物资出版社 * |
| 化学工业出版社编: "《中国化工产品大全 第三版》", 31 January 2005, 化学工业出版社 * |
| 叶伊琳: "《美容医学概论》", 30 April 2012, 郑州大学出版社 * |
| 朱洪法等: "《精细化工产品制造技术》", 31 January 2002, 金盾出版社 * |
| 林育华: "《周超凡论中药 第2版》", 30 November 2014, 人民军医出版社 * |
| 王昌涛等: "《化妆品植物添加剂的开发与应用》", 30 April 2013, 中国轻工业出版社 * |
| 王锦鸿等: "《临床实用中药辞典》", 30 November 2003, 金盾出版社 * |
| 马振友等: "《皮肤美容化妆品制剂手册》", 31 March 2004, 中医古籍出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108524316A (en) * | 2018-07-18 | 2018-09-14 | 张永 | A kind of Whitening, spot composition and preparation method thereof |
| CN110964070A (en) * | 2019-12-05 | 2020-04-07 | 广州汀兰生物科技有限公司 | Preparation method of troxerutin and application of troxerutin in whitening and skin-care products |
| CN110964070B (en) * | 2019-12-05 | 2022-09-27 | 广州汀兰生物科技有限公司 | Preparation method of troxerutin and application of troxerutin in whitening and skin-care products |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69637240T2 (en) | ANTIBACTERIAL / BACTERICIDES / ANTISEPTIC AGENT, DERMATOLOGICAL PREPARATION AND TENSID COMPOSITION | |
| CN109453096A (en) | A kind of antisenility skin care facial mask essence and preparation method thereof | |
| CN109498481A (en) | A kind of antisenility skin care hydrogel mask matrix and preparation method thereof | |
| CN107095843A (en) | A kind of facial mask containing fermented tea | |
| CN108078810A (en) | The skin care cosmetic composition of Whitening, spot | |
| CN109316363A (en) | A method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation | |
| JP2012513389A (en) | Antimicrobial agents, compositions and products containing the same, and methods of using these compositions and products | |
| KR102228171B1 (en) | Sanitizer mix composition | |
| KR20180032479A (en) | Nano Liposome Composition Comprising Peptide for Easy Penetrating into Skin | |
| KR20150064454A (en) | Skin External Agent Formulation Containing High Concentrated Hyaluronic Acid and Preparing Method Thereof | |
| KR20130058901A (en) | Skin external composition having excellent bactericidal activities | |
| CN104255721B (en) | A kind of anticorrosion and bactericidal agent composition containing 2,4,4 '-three chloro-2 '-dihydroxy diphenyl ether and purposes | |
| KR100666830B1 (en) | Alginate microcapsule encapsulated extract of horseradish and preparation method thereof | |
| CN108812690A (en) | A kind of anti-mite preparation and preparation method thereof | |
| KR20150058604A (en) | Antiseptic composition for water tissue | |
| KR102093827B1 (en) | Cosmetic compositions containing poly(butyl cyanoacrylate) | |
| Amnuaikit et al. | Formulation development and facial skin evaluation of serum containing jellose from tamarind seeds | |
| KR102198696B1 (en) | Method for the production of external application sanitizer composition with high content of ethanol and moisturizing effect | |
| KR101674512B1 (en) | Cosmetic composition with effect of proliferation of lactic acid bacteria and anti-bacterial activity and manufacturing method thereof | |
| CN105770999B (en) | A kind of composite biological material for eliminating bacterial biofilm | |
| CN107137306A (en) | A kind of Nano Silver purification, which is washed, unloads two-in-one solution | |
| CN108743502B (en) | A kind of bamboo vinegar toothpaste and preparation method thereof | |
| CN108078838A (en) | Skin whitening, moisturizing skin care item | |
| CN109350570A (en) | A kind of cosmetics preservative and its application based on natural plant composition | |
| CN108030711A (en) | Skin whitening care cosmetics |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20180529 |