CN108078652A - Posterior chamber type has crystal eye intraocular lens - Google Patents
Posterior chamber type has crystal eye intraocular lens Download PDFInfo
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- CN108078652A CN108078652A CN201710010110.XA CN201710010110A CN108078652A CN 108078652 A CN108078652 A CN 108078652A CN 201710010110 A CN201710010110 A CN 201710010110A CN 108078652 A CN108078652 A CN 108078652A
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- intraocular lens
- rear surface
- opticator
- lens
- curvature
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1602—Corrective lenses for use in addition to the natural lenses of the eyes or for pseudo-phakic eyes
- A61F2/161—Posterior chamber lenses for use in addition to the natural lenses of the eyes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea
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- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Ophthalmology & Optometry (AREA)
- Chemical & Material Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Prostheses (AREA)
Abstract
The present invention discloses a kind of back room embedded types crystal eye intraocular lens, the intraocular lens is made of high index of refraction acrylate materials, it is made of opticator and support section, it is implanted between natural lens and iris, is supported on by the button loop to match with ciliary groove size in ciliary groove.Intraocular lens's rear surface of the present invention is mellow and full, has the face shape of concave-concave, itself spherical aberration is small, and opticator is big.The intraocular lens not only can guarantee after the implantation with the gap of ocular tissue safety, but also can guarantee free from glare, preferable image quality.
Description
Technical field
The present invention relates to there is crystal eye intraocular lens, relating more specifically to posterior chamber type has crystal eye intraocular lens.
Background technology
Posterior chamber type is made of crystal eye intraocular lens opticator and support section, be implanted to natural lens with
Between iris, button loop is supported in ciliary groove, as shown in Figure 1, to change the refractive status of human eye, it is near particularly to correct height
Depending on.
For having crystal eye intraocular lens, except realize correction of refractive errors function in addition to, it is important the considerations of factor be
The structure of intraocular lens is for the security after implantation.
Enough spacing must be kept between corneal endothelium, natural lens after having crystal eye intraocular lens implantation, prevented
Only trigger corneal endothelium damage or natural lens muddy due to intraocular lens contacts with corneal endothelium and natural lens.By
Space is extremely limited between iris and natural lens, therefore surgical procedure difficulty is big, and to the size of intraocular lens just like
Lower strict requirements:
1)Spacing between intraocular lens and natural lens is enough, prevents two kinds of crystalline lenses from contacting with each other, causes contact
Cataract, this requires intraocular lens to have enough springs of arch;
2)Spacing is enough between intraocular lens and corneal endothelium, prevents intraocular lens from being contacted with corneal endothelium, causes cornea
Endothelial injuries, this requires the spring of arch of intraocular lens cannot be excessively high;
3)Intraocular lens's overall length must be matched with ciliary groove size so that intraocular lens can be just stuck in ciliary groove.
If intraocular lens is long compared with ciliary groove, intraocular lens will arch upward, though away from natural lens, in cornea
Bark graft is near, easily causes corneal endothelium damage, and room angle is oppressed, and easily causes room angle closure, and causes the complication such as glaucoma;
And if intraocular lens is too short compared with ciliary groove, easily cause intraocular lens's support force insufficient, under iris compressing with day
Right lens contact, and cause cataract.
In addition, there is following Consideration in the design aspect of intraocular lens:
1)Room angle:As intraocular lens is implanted, human eye iris is influenced by intraocular implants' shape, is arched upward slightly, will be made
Human eye room angle becomes smaller, as shown in Figure 2.If room angle is closed, i.e., iris is extremely close with cornea interior surface, and room angle approaches to turn off shape
State(Nearly 0 degree of room corner connection), then the complication such as room angle closed intraocular hypertension, glaucoma are caused, therefore intraocular lens should in design
Reduce the influence caused by room angle as far as possible, the room angle of bigger is reserved for human eye.
2)Opticator:Refer to the circular diameter containing optical design features for being concentric with intraocular lens's optical axis, human eye is dim
Under the conditions of pupil expand, to prevent glare problem, the opticator of intraocular lens should try one's best greatly.
In conclusion in order to ensure the security and validity after artificial lens implanting, it should ensure intraocular lens
As far as possible big opticator, as far as possible more intraocular lens with natural lens and with the gap of corneal endothelium, it is as far as possible big surplus
Remaining room angle.However, there is mutually restriction between opticator size and remaining room angle and between spring of arch and remaining room angle
Relation, for an equal amount of human eye, intraocular lens's opticator is bigger, then the point that intraocular lens contacts with iris is got over
Close to room angle, the degree that iris is arched upward is higher, and remaining room angle is smaller.Likewise, intraocular lens vault Gao Yuegao, then iris
The degree to be arched upward is higher, and remaining room angle is also smaller.
Existing ciliary groove support at present, posterior chamber type have the ICL of crystal eye intraocular lens only STAAR companies production.For
Make intraocular lens with corneal endothelium distance enough, existing posterior chamber type have crystal eye intraocular lens using it is preceding it is flat after it is recessed
Structure realizes the diopter that intraocular lens bears.
The problem of this design, is that, when intraocular lens's diopter is larger, rear surface radius of curvature is smaller, optical section
Point edge is easily contacted with human eye natural lens, and causes natural lens that friction is locally subject to cause cataract.In order to reduce
This risk can take the mode of increase sagitta, make intraocular lens's rear surface whole with natural lens keep safety away from
From.However, with the angle that the increase of sagitta, human eye iris are formed with cornea interior surface, i.e. room angle becomes smaller, and room angle is easily caused to be closed
Mould assembly glaucoma.Therefore existing intraocular lens reduces opticator, so as to reduce light by the way of opticator size is sacrificed
It learns part edge to thicken caused by diopter, ensures to leave sufficient space between intraocular lens and natural lens, and
Keep the stabilization at room angle.For example the ICL of STAAR, the diameter maximum of intraocular lens's opticator are only capable of reaching 5.5mm, with
The increase opticator of diopter constantly reduces, and is only capable of maintaining the opticator of a diameter of 4.65mm big for the diopter of -20D
It is small.
Intraocular lens's opticator small the problem of causing dazzle, influence contrast sensitivity, especially pupil of human compared with
In the case of big, such as dim, night-environment, existing posterior chamber type have the complication of the common postoperative dazzle of crystal eye intraocular lens.And
And clinical medicine statistical result shows that the pupil of high myopia is generally bigger than normal eye, therefore existing intraocular lens
The smaller design of the higher opticator of diopter more easily causes glare problem.
Fig. 3 shows that two panels has the intraocular lens 1,2 of preceding flat back concave surface shape.The high phase of vault of intraocular lens 1,2
Together.The absolute value of the diopter of intraocular lens 1 is less than the absolute value of the diopter of intraocular lens 2, after intraocular lens 1
Surface curvature radius R1 is more than the rear surface radius of curvature R 2 of intraocular lens 2.At identical diameter, intraocular lens 1 from
The spacing of natural lens is more than spacing of the intraocular lens 2 from natural lens.In order to increase intraocular lens 2 and natural crystalline
The spacing of shape body is, it is necessary to reduce the opticator of intraocular lens 2.
That is, the intraocular lens that the absolute value of diopter is bigger, rear surface radius of curvature is smaller, and rear surface is steeper
It is high and steep, it is nearer from natural lens at identical optical diameter, in order to increase gap, using the method for reducing opticator.
In addition, for the intraocular lens of double spherical designs, the spherical aberration entrained by intraocular lens itself will
Human eye vision quality can be impacted, the big intraocular lens of spherical aberration generates dazzle easily at night or larger pupil of human and shows
As.Fig. 4 shows the relation of intraocular implants' body front surface of negative diopter and the face shape of rear surface and self-contained spherical aberration.It can
See, the self-contained spherical aberration of preceding flat rear recessed negative diopter intraocular lens is maximum.Therefore existing at present there is the crystal eye manually brilliant
A large amount of spherical aberrations can be brought to human eye after the implantation of shape body, influence human eye vision quality, especially dim condition or pupil of human is larger
In the case of visual quality.
The content of the invention
The present invention, which proposes a kind of posterior chamber type, crystal eye intraocular lens, while with big opticator,
It can ensure gap enough between intraocular lens and natural lens, larger room angle can be kept.That is, this hair
It is safe with the gap of ocular tissue after the implantation that bright posterior chamber type has crystal eye intraocular lens not only to can guarantee, but also can guarantee free from glare
With preferable image quality.
Specifically, the present invention, which proposes a kind of posterior chamber type, crystal eye intraocular lens, and the intraocular lens is implanted
To between natural lens and iris, the intraocular lens includes opticator and support section, and the support section is propped up
Support matches in ciliary groove and with ciliary groove size, and the opticator has front surface and rear surface, and the front surface is
The intraocular lens is implanted to nearer from eye cornea that surface after human eye, and the rear surface is the intraocular lens
That surface from eye cornea farther out after human eye is implanted to, the intraocular lens has negative diopter, the front surface
It is concave surface with the rear surface.
According to one embodiment of present invention, the ratio between the front surface and radius of curvature of the rear surface are arrived 0.11
In the range of 184.22.
According to one embodiment of present invention, the ratio between the front surface and radius of curvature of the rear surface are arrived 0.39
In the range of 184.22.
According to one embodiment of present invention, the diameter of the opticator is more than or equal to 5.5mm.
According to one embodiment of present invention, the intraocular lens is made of flexible folding acrylate materials.
According to one embodiment of present invention, the refractive index of the flexible folding acrylate materials for 1.46 ~
1.55。
According to one embodiment of present invention, the refractive index of the flexible folding acrylate materials for 1.48 ~
1.52。
According to one embodiment of present invention, the rear surface radius of curvature of the intraocular lens is more than or equal to 8.0mm.
According to one embodiment of present invention, the rear surface radius of curvature of the intraocular lens is more than or equal to 8.5mm.
According to one embodiment of present invention, the rear surface radius of curvature of the intraocular lens is more than or equal to 10.0mm.
Description of the drawings
Fig. 1 is the schematic diagram for the implantation position that posterior chamber type has crystal eye intraocular lens;
Fig. 2 is the schematic diagram that posterior chamber type has crystal eye intraocular lens gap after the implantation and room angle;
Fig. 3 shows that two panels has the schematic diagram of the intraocular lens of preceding flat back concave surface shape after the implantation;
Fig. 4 shows the relation of intraocular implants' body front surface of negative diopter and the face shape of rear surface and self-contained spherical aberration;
Fig. 5 a show conventional preceding flat back concave surface shape(Namely front surface is plane, rear surface is concave surface)Intraocular lens exist
Position in human eye;
Figure 5b shows that the bi-concave shapes with the intraocular lens of Fig. 5 a with identical diopter(Namely front surface and rear surface it is equal
For concave surface)Position of the intraocular lens in human eye;
Fig. 6 shows the specific technical solution of the present invention.
Specific embodiment
Inventive concept according to the present invention, using the face shape of concave-concave, by intraocular lens in rear surface(Close to natural crystalline
That surface of shape body)The thickened edges of opticator move to front surface(Close to that surface of cornea), make intraocular implants
Body is on the premise of identical diopter is kept, the gap increase between rear surface and natural lens;Sagitta is reduced simultaneously, is increased
Big opticator, so as to keep stable room angle.
Fig. 5 a show conventional preceding flat back concave surface shape(Namely front surface is plane, rear surface is concave surface)Intraocular implants
Position of the body in human eye, wherein H1 are the spacing of intraocular lens rear surface opticator center and natural lens, and H2 is
The spacing at intraocular lens rear surface opticator edge and natural lens.Due to natural lens rear surface radius of curvature compared with
Small, face shape is more precipitous, and intraocular lens approaches rapidly at opticator edge with natural lens, and because natural lens
Front surface is convex surface, makes this close to being amplified rapidly, easily generates annular and sharply contacts, natural lens is caused to be rubbed
It is and muddy.
Figure 5b shows that the bi-concave shapes with the intraocular lens of Fig. 5 a with identical diopter(Namely front surface and rear table
Face is concave surface)Position of the intraocular lens in human eye, wherein H1 for intraocular lens rear surface opticator center with
The spacing of natural lens, H2 are the spacing of intraocular lens rear surface opticator edge and natural lens.Due to concave-concave
The trend of concavees lens thickened edges is moved to front surface by the intraocular lens of face shape, and intraocular lens's rear surface is made to become relatively more
Add flat, so that the gap between intraocular lens and natural lens becomes larger, and make intraocular lens's rear surface more
It is mellow and full, the hidden danger that annular sharply contacts is eliminated, reduces incidence of cataract.Intraocular lens is in entire rear surface and natural lens
The spacing of body reaches unanimity, and the risk of point-like contacts does not occur, it is possible to which the whole sagitta for reducing intraocular lens makes one
The lenticular room angle of work obtains space.On the other hand, if room angle is kept not increase, opticator diameter can be increased.
For the technical characteristic of the accurate characterization present invention, using the ratio between radius of curvature of a front surface and a rear surface as characterization
Parameter:
Wherein, Ra, Rp are respectively the front surface of intraocular lens and the radius of curvature of rear surface, and the front surface of intraocular lens is
Refer to after intraocular lens is implanted to human eye, light is by first optical surface of intraocular lens, i.e., nearer from eye cornea
That surface;After intraocular lens's rear surface refers to that intraocular lens is implanted to human eye, light pass through intraocular lens second
A optical surface, i.e. that surface from eye cornea farther out.
Fig. 6 shows the specific technical solution of the present invention.As shown in fig. 6, the intraocular lens of the present invention is divided into optics
Part and support section, support section are supported in ciliary groove and are matched with ciliary groove size.The intraocular implants of the present invention
Body has negative diopter.The opticator of the intraocular lens of the present invention is bi-concave shape namely intraocular implants of the invention
The front surface and rear surface of the opticator of body are concave surface.Preferably, in some embodiments, intraocular lens of the invention
The ratio between the radius of curvature of a front surface and a rear surface of opticator K in the range of 0.11 to 184.22.It is furthermore preferred that one
In a little embodiments, the ratio between radius of curvature of a front surface and a rear surface of opticator of intraocular lens of the invention K is 0.39
To in the range of 184.22.By the way that K values are chosen within the above range, it can further reduce the aberration of intraocular lens, together
When can ensure it is constant at room angle and minimum clearance on the premise of, obtain the opticator diameter of bigger, ensureing implantation safety
On the premise of property, reduce dazzle.
The intraocular lens of the present invention can be made of flexible folding acrylate material.In some embodiments, should
The refractive index of flexible folding acrylate material is more than or equal to 1.46.Preferably, in some embodiments, the flexible folding
The refractive index of acrylate material is 1.46 ~ 1.55.It is furthermore preferred that in some embodiments, the flexible folding acrylate
The refractive index of material is 1.48 ~ 1.52.By the way that refractive index is chosen within the above range, intraocular lens of the invention not only may be used
To ensure relatively thin thickness, increase the gap of intraocular lens and eye inner tissue, reduce intraocular lens and contact natural lens
Risk, moreover it is possible to ensure relatively low aberration, reduce dazzle, improve intraocular lens's optical quality.In some embodiments,
Diopter of the intraocular lens of the present invention in aqueous humor is -30.0D ~ 0.
In some embodiments, the rear surface radius of curvature of intraocular lens of the invention is more than or equal to 8.0mm.It is preferred that
, in some embodiments, the rear surface radius of curvature of intraocular lens of the invention is more than or equal to 8.5mm.It is furthermore preferred that
In some embodiments, the rear surface radius of curvature of intraocular lens of the invention is more than or equal to 10.0mm.The artificial crystalline substance of the present invention
Shape body is more mellow and fuller compared with natural lens profile, reaches unanimity in the spacing of entire rear surface and natural lens, does not send out
The risk of raw point-like contacts eliminates the hidden danger that annular sharply contacts, and reduces incidence of cataract.Intraocular implants' physical efficiency of the present invention
Enough diameters for ensureing the opticator in whole power ranges are more than or equal to 5.5mm.
Table 1 shows the specific embodiment based on technical scheme, wherein, Ra be front surface radius of curvature, Rp
For rear surface radius of curvature, and room angle, minimum clearance(Intraocular lens and the distance of natural lens closest approach)All in accordance with
Iso standard human-eye model calculates, the only prediction as design effect.When used human-eye model difference, room angle and minimum
The result in gap may be different, but trend is similar.In contrast, minimum clearance is that have crystal eye intraocular lens's security most heavy
The index wanted, with reference to clinical manifestation, it is believed that minimum clearance is relatively reasonable not less than 0.5mm.And the minimum requirements at room angle is
" not being closed ", it is generally recognized that 10 degree or more of room angle is safer, and 15 degree or more of room angle is more outstanding.
Table 2 shows the opticator diameter of intraocular lens and the prior art intraocular lens of the present invention, Fang Jiao, most
The control of small―gap suture, spherical aberration.As it can be seen that the intraocular lens of the present invention can ensure at room angle and the constant premise of minimum clearance
Under, the opticator diameter of bigger is obtained, on the premise of being implanted into security in guarantee, reduces dazzle.With existing skill
Art is compared, and the identical diopter opticator diameter of intraocular lens of the invention can obtain the increase of 0.8mm or so.
Under technical scheme, the rear surface face shape of intraocular lens is more mellow and full, can reduce being in contact property
The risk of cataract.
In addition, as can also be seen from Table 2, with bi-concave shape intraocular lens per se with spherical aberration smaller,
More outstanding optical quality can be obtained after implantation human eye.
Table 3 is assumes that the intraocular lens of the present invention is made with prior art intraocular lens of identical material, two
The control of the opticator diameter, Fang Jiao, minimum clearance, spherical aberration of kind intraocular lens.As it can be seen that bi-concave proposed by the invention
Shape can be individually for crystal eye intraocular lens and bring the increase of about 0.3mm or so opticator diameters, and can show simultaneously
It writes and reduces spherical aberration.
Although reference(It is one or more)Exemplary embodiment describes the present invention, but those skilled in the art will
Understand, wanted the invention is not restricted to precise structure described herein and component, and without departing from such as appended right
In the case of the spirit and scope of the invention for asking restriction, various modifications, variation and deformation are understood that from the description of front.The present invention
From the limitation of the shown sequence of step because some steps can in a different order and/or with other steps simultaneously into
Row.Therefore, the invention is not restricted to disclosed(It is one or more)Specific embodiment, but will include falling wanting in appended right
All embodiments in the range of asking.
Claims (10)
1. a kind of posterior chamber type has a crystal eye intraocular lens, the intraocular lens be implanted to natural lens and iris it
Between, the intraocular lens includes opticator and support section, and the support section is supported in ciliary groove and and eyelash
Shape ditch size matches, and the opticator has front surface and rear surface, and the front surface is that the intraocular lens is implanted to
That surface nearer from eye cornea after human eye, the rear surface are that the intraocular lens is implanted to after human eye from human eye angle
That surface of film farther out, the intraocular lens have negative diopter, which is characterized in that the front surface and the rear table
Face is concave surface.
2. intraocular lens according to claim 1, which is characterized in that the curvature half of the front surface and the rear surface
The ratio between footpath is in the range of 0.11 to 184.22.
3. intraocular lens according to claim 2, which is characterized in that the curvature half of the front surface and the rear surface
The ratio between footpath is in the range of 0.39 to 184.22.
4. intraocular lens according to claim 1, which is characterized in that the diameter of the opticator is more than or equal to
5.5mm。
5. intraocular lens according to claim 1, which is characterized in that the intraocular lens is by flexible folding propylene
Esters of gallic acid material is made.
6. intraocular lens according to claim 5, which is characterized in that the flexible folding acrylate materials
Refractive index is 1.46 ~ 1.55.
7. intraocular lens according to claim 5, which is characterized in that the flexible folding acrylate materials
Refractive index is 1.48 ~ 1.52.
8. intraocular lens according to claim 1, which is characterized in that the rear surface radius of curvature of the intraocular lens
More than or equal to 8.0mm.
9. intraocular lens according to claim 1, which is characterized in that the rear surface radius of curvature of the intraocular lens
More than or equal to 8.5mm.
10. intraocular lens according to claim 1, which is characterized in that the rear surface curvature of the intraocular lens half
Footpath is more than or equal to 10.0mm.
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CN201710010110.XA CN108078652A (en) | 2017-01-06 | 2017-01-06 | Posterior chamber type has crystal eye intraocular lens |
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CN201710010110.XA CN108078652A (en) | 2017-01-06 | 2017-01-06 | Posterior chamber type has crystal eye intraocular lens |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN112494175A (en) * | 2020-11-25 | 2021-03-16 | 杭州爱晶伦科技有限公司 | Posterior chamber type aspheric intraocular lens with lens |
CN113040976A (en) * | 2021-03-04 | 2021-06-29 | 天津世纪康泰生物医学工程有限公司 | Ultrathin zero-spherical-aberration implantable myopia lens |
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CN205831963U (en) * | 2016-04-05 | 2016-12-28 | 西安浦勒生物科技有限公司 | There is crystal camera oculi posterior artificial intraocular lenses |
CN207492838U (en) * | 2017-01-06 | 2018-06-15 | 爱博诺德(北京)医疗科技有限公司 | Posterior chamber type has crystal eye intraocular lens |
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WO1998005273A1 (en) * | 1996-08-06 | 1998-02-12 | Chiron Vision Corporation | Foldable intraocular lens |
WO2001008606A1 (en) * | 1999-08-02 | 2001-02-08 | Ioltechnologie-Production | Intraocular implant for crystalline lens |
CN1387422A (en) * | 1999-11-10 | 2002-12-25 | Iol技术产品有限责任公司 | Pre-crystalline intraocular implant |
CN1550225A (en) * | 1999-11-10 | 2004-12-01 | IOL������Ʒ�������ι�˾ | Pre-crystalline intraocular implant |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN112494175A (en) * | 2020-11-25 | 2021-03-16 | 杭州爱晶伦科技有限公司 | Posterior chamber type aspheric intraocular lens with lens |
CN113040976A (en) * | 2021-03-04 | 2021-06-29 | 天津世纪康泰生物医学工程有限公司 | Ultrathin zero-spherical-aberration implantable myopia lens |
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