CN1466934A - Intraocular phototropism lens and implantation method - Google Patents
Intraocular phototropism lens and implantation method Download PDFInfo
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- CN1466934A CN1466934A CNA031154980A CN03115498A CN1466934A CN 1466934 A CN1466934 A CN 1466934A CN A031154980 A CNA031154980 A CN A031154980A CN 03115498 A CN03115498 A CN 03115498A CN 1466934 A CN1466934 A CN 1466934A
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Abstract
An intra-ocular refraction lens is composed of a circular optical body and at least one supporter. The curvature radius for the front surface of said optical body is determined by actual diopter. The back surface of said refraction lens appears as a concave curved surface. A method for reversibly transplanting said refraction lens into eye is also disclosed, which is suitable for the patient of high-level myopia or hyperopia.
Description
Technical field
The present invention relates to a kind of ophthalmic crystal and method for implantation thereof.More particularly, the present invention relates to a kind ofly can to implant in the eyes, exist jointly, in order to the dioptric lens of corrective ophthalmic refractive error with a kind of these ophthalmic dioptric lens are implanted method in eyes with people's natural crystal.
Background technology
In order correctly to describe content of the present invention, at first following term is made explanations or define.
Nature crystal: be meant the natural crystal mirror in mankind's (or extensively referring to mammal) eyes.Nature crystal outside is surrounded by the elastic membrane vesicle of one deck, also is the capsule bag sometimes.Mention among the present invention actual being meant on the membrane vesicle of natural crystal front surface on the natural plane of crystal.The nature crystal is transparent and can regulates focusing power that it can make closely the object of (or far away) distance can drop on imaging on the retina.When the mankind enter beginning in 40 years old, this adjusting focusing power fell into a decline, and began to completely lose this adjusting focusing power to about 50 years old, Here it is our said presbyopia.
Cataract: be meant that the natural crystal of mankind's (or extensively referring to mammal) begins to be changed to muddiness by pellucidity gradually, cause incident beam can not arrive retina, cause visual deterioration or as blind as a bat thus.The general treatment method is to extract the natural crystal of cataract patient, replace with synthetical crystal, and rectification is by behind the cataract extraction and the refractive error that causes.Correctly select the artificial intraocular lenses for use, can after operation, can wear nearly (or far away) glasses and just can see the world on every side clearly.
Artificial intraocular lenses: refer to the eyeglass that artificial material is made, can be used to replace the natural crystal mirror of cataract patient.Generally be placed on the crystalline original position of nature, promptly in the capsule bag.
Refractive error: or claim vision refractive error, refraction of eye error.Human eyes are polynary optical bodies.Cornea is the convex surface type, the nature crystal is asymmetrical biconvex mirror body, the close coordination of the curvature of cornea and crystalline naturally curvature and the distance between them just can make correct the dropping on the retina of imaging, and any eye eyesight decline that causes owing to optical parallax all is loosely referred to as refractive error.It comprises: myopia, hypermetropia and astigmatism etc.
Face: refer to the vision health state, promptly do not have myopia, also do not have hypermetropia or astigmatism, become image focus just in time to drop on the retina.
Ophthalmic dioptric lens: or be called for short dioptric lens, be meant that implanting human (or extensively referring to mammal) ophthalmic and natural crystal exists simultaneously and work simultaneously and correct the optical glass of vision refractive error.In general, the ophthalmic dioptric lens are made up of an optical bodies and at least one supporter.
Optical bodies: being meant the center ingredient of ophthalmic dioptric lens, can be biconvex mirror, biconcave mirror, concave mirror behind preceding recessed back convex lens or the lordosis.It is used for making incident beam to gather on the retina, and its diopter D commonly used represents.As ,-1D is exactly myopia 100 degree of often saying, and+1D is exactly hypermetropia 100 degree of often saying.
Supporter: directly be connected, be used for the structure division of support of optical body desired center position in eye with optical bodies.
Cornea: the curved face type tissue of eyes transparent front.
Iris: the annular pigmented film of facies posterior corneae, in be pupil.
Ciliary zonule: or be called for short little band, refer to be bonded at ciliary zonule around the nature crystal equator.
Camera oculi anterior: the locus between cornea and iris.
Camera oculi posterior: general reference is positioned at the locus of facies posterior iridis.In the present invention, often refer to be located at the locus of facies posterior iridis and natural crystal front.Iris neither belongs to the anterior chamber, does not belong to back room again, but as the demarcation line of distinguishing forward and backward room.
Pocket knife otch: cataract operation surgeon Essential Terms.Refer generally on cornea or the long otch of the about 3mm of edge slit, the artificial intraocular lenses of an about 6mm diameter can implant this otch after contraction.This operation does not need suture in the ordinary course of things, and wound can oneself be sewed up.
During the Second World War, many Britain ophthalmologists are diagnosing by polyacrylate (as polymethyl methacrylate, when protruding into the injury that eyes cause, the aircraft windows door shell body fragment of PMMA) making notices, outside hindering when protruding into except fragment, PMMA itself does not cause any side effect that brings owing to rejection to eye tissue.Therefore, common processing method is that PMMA is stayed in the eyes, is not taken out and do not carry out surgical operation, causes new infection to avoid performing the operation.People recognize the relative inertness of PMMA to eye tissue thus.Soon, the sharp doctor of Britain Harold Reed (Dr.Harold Ridley) is on November 29th, 1949, interplantation first artificial intraocular lenses who makes with PMMA in the eyes of cataract patient.This indicates the birth of artificial intraocular lenses's new technique.
Since the sharp doctor of Harold's Reed invented first artificial intraocular lenses, the artificial intraocular lenses had obtained very big progress.The first, time accepted cataract operation calendar year 2001 nearly 1,000 5 million peoples in the whole world, this is all surgical operation kind apoplexy due to endogenous wind maximum a kind of of number that undergo surgery.In addition, the success rate of cataract operation is more than 99%, the patient after being treated surgically 15-30 minute, the just world that can look around with eyes.The second, the late nineteen eighties, the folding artificial intraocular lenses is come out.Folding artificial intraocular lenses's use has reduced the size of operating scissors otch, and reduce degree only about half of about.For example, with the 6mm diameter artificial intraocular lenses that hard PMMA makes, need the long operating scissors otch of 6mm at least; And with the 6mm diameter artificial intraocular lenses that soft material is made, it is wide to be folded into 3mm, just means that also the sheared edge of this operation only needs 3mm long.The folding artificial intraocular lenses remains present cataract and operates on state-of-the-art technology in the surgical technic field.At present, the soft material in leading market is generally soft polypropylene acid esters material or silastic material.
More than said all artificial intraocular lensess all to be cataract patients extracing the artificial crystal that is used for replacing behind its natural crystal.Simultaneously, the artificial intraocular lenses also brings great convenience for cataract patient's vision restoration.For example, the cataract patient of myopia 1000 degree (or hypermetropia 500 degree) does not just need to wear 1000 degree myopia (or 500 degree hypermetropias) glasses after operation.This is because artificial intraocular lenses's optical mirror can be corrected patient at preoperative refractive error.Yet same patient if do not do pioneering operation, just can't correct the refractive error that is produced by the eyeball structure of modification, have to correct defects of vision by wearing glasses.
In recent years, do not need the problem of wearing glasses, produced many new refractive surgeries in order to solve myopia (or hypermetropia) patient.Refractive surgery is meant that the ophthalmologist uses different surgical operations to change myopia (or hypermetropia, or presbyopia) patient's eye structure, the patient light beam that enters eyes focused on the retina, so that can all can clearly see image under the situation of not wearing glasses.Such as, laser technology has been widely applied on the cornea refractive surgery, abbreviates the LASIK technology as, is used for modifying the refractive index of cornea with myopia correction, hypermetropia or astigmatism.With regard to the U.S., will there be nearly 1.5 million peoples time accept laser therapy in 2002.In China, laser surgery is extensively promoted in each big and medium-sized cities, the whole nation.Yet laser surgery only is confined to minuent or medium myopia, farsighted person.For being higher than the near-sighted of 800 degree or being higher than 500 hypermetropias of spending, laser surgery can't thoroughly be corrected defects of vision.This is that under the normal condition, the average thickness of cornea is 0.5mm because by the laser corrective procedure, the minimum thickness that all patients should keep cornea is 0.25mm.For the high myopia patient, the thickness of center cornea will excise more than the 0.25mm, effectively myopia correction.But if the above cornea of excision 0.25mm, the corneal thickness that stays is too thin, easily causes other wound.Therefore, the high myopia patient only is remedied to low myopia with laser usually, and the patient must wear the low myopia glasses and correct remaining myopia.In addition, reach the rectification diopter because laser surgery is a part of excising cornea, it is irreversible, that is to say, the cornea that cuts away can't refill.
Chinese patent publication number CN1162254, open day on October 15th, 1997, the name of innovation and creation is called intraocular contact lens and method for implantation thereof, this application case discloses a kind of intraocular contact lens, its basic feature is that this intraocular contact lens has a transition between glasses portion and glasses our department, to reduce the formation at edge as far as possible.The technical scheme weak point of this invention is: the first, and this intraocular contact lens only is applicable to camera oculi posterior, and does not mention any ophthalmic dioptric lens that are applicable to camera oculi anterior.The second, it mainly is to the narration of the structure of this contact lens front surface, and is unclean to the narration of contact lens rear surface structure.Because have only directly contact iris back of front surface, and the rear surface is bumped at all less than the iris back.
Under normal conditions, the side effect of irrational intraocular contact lens design most probable generation is exactly because intraocular contact lens directly touches the nature crystal to cause nature crystal generation mutation, it is muddy that consequently natural crystal gradually becomes, the cataract of promptly early turning white.
Up to now, for high myopia (or high hypermetropia) patient, no matter be, also without any the refractive surgery or the product of the national medical instrument management of a kind of process department approval listing in China or in the U.S..Yet for high myopia (or high hypermetropia) patient, they are once lose glasses, and life and action will be very limited, severe patient even can't carry out any activity.Concerning the younger generation people, many industries (police, bodyguard, soldier, athlete etc.) all can be kept high myopia (or high hypermetropia) patient outside of the door.Therefore, high myopia (or high hypermetropia) is actually a kind of " with visual disabilities ".
Therefore, conquering the refractive surgery of this " with visual disabilities ", is a kind of challenge to ophthalmology optometry expert not only, also is a difficult problem that presses for solution in our modern life.The present invention utilizes to implant the visual problems that the dioptric lens in the eyes are corrected high myopia (or high hypermetropia) patient, makes them not need wear a pair of spectacles just can clearly see the world on every side.In addition, the present invention not only is suitable for high myopia (or high hypermetropia) patient, also is applicable to low myopia (or hypermetropia) patient certainly.Also have, different with cataract operation, the ophthalmic dioptric lens among the present invention are to use after not people's natural lens extraction, but use when existing jointly with people's natural crystal.Therefore, crystalline naturally adjusting focusing power is still constant.Come therefrom, the ophthalmic dioptric lens that relate among the present invention give myopia (or hypermetropia) patient particularly high myopia (or high hypermetropia) patient a kind of new refractive surgery technology is provided.
Summary of the invention
Primary and foremost purpose of the present invention is to overcome deficiency of the prior art, provide a kind of diopter wide range, can avoid the cataractous ophthalmic dioptric lens of early onset that cause owing to foreign body well.
The present invention also aims to provide a kind of ophthalmic dioptric lens that utilize biocompatible materials to make.
Further aim of the present invention is to provide a kind of ophthalmic dioptric lens of being made by flexible material, and this soft ophthalmic dioptric lens can shrink (folding, curl, stretching or compression etc.) back and implant eyes by the pocket knife otch.
Further object of the present invention is to provide a kind of method of simple implantation ophthalmic dioptric lens.
A further object of the invention provides a kind of method of reversible implantation ophthalmic dioptric lens.By this method, can realize repeatedly using the ophthalmic dioptric lens refractive error of correcting defects of vision.
In order to solve the problems of the technologies described above, the present invention is achieved by the following technical solutions:
The invention provides a kind of ophthalmic dioptric lens, be connected with at least one supporter by optical bodies and form, described optical bodies and supporter have front surface and rear surface, optical bodies be shaped as circle, its front surface radius of curvature size is decided according to its diopter size.The rear surface of described dioptric lens is concave curved surface shape, the optical bodies rear surface fuse glossily with supporter first rear surface and both radius of curvature identical.
The present invention also provides a kind of ophthalmic dioptric lens, form by a circular optical bodies and at least two linear supporters, described linear supporter directly is connected with optical bodies, so that optical bodies stably is fixed on eyes anterior chamber space pupil center location, avoid described optical bodies to contact with the cornea interior surface layers.
The biocompatible materials that ophthalmic dioptric lens among the present invention use can be firm material, as PMMA.Be more preferably the material that has elasticity and shape-memory properties, in the serviceability temperature scope, is elastic stage in this class material, include but is not limited to soft polypropylene esters of gallic acid, silicone rubber kinds, gel-like and other macromolecule soft materials.
The invention provides a kind of method of simple, reversible implantation ophthalmic dioptric lens,, can realize repeatedly using the ophthalmic dioptric lens refractive error of correcting defects of vision by this method.May further comprise the steps: on the eyes cornea or its edge slit one opening; Described dioptric lens are shunk (folding, curl, stretching or compression etc.) and reduce its sectional dimension; Dioptric lens after shrinking are implanted ophthalmic by the pocket knife otch; The dioptric lens that shrink are returned to the diopter of original shape and expectation.
Compared with prior art, the invention has the beneficial effects as follows:
The ophthalmic dioptric lens rear surface curved surface that the present invention describes is slick, and the surface curvature radius is roughly the same with human natural crystal front surface radius of curvature thereafter.Therefore, when the ophthalmic dioptric lens were implanted to camera oculi posterior, the surface was attached to nature crystal surface before basically after its whole lens, has the very thin aqueous humour of one deck between the two; On the other hand, because the aqueous humour of ophthalmic is to flow to the anterior chamber from back room by pupil, this hydatoid flowing makes the thin water layer that is clipped between ophthalmic dioptric lens and the natural crystal obtain constantly replenishing and replacing upgrading, and avoided this typical side effect of early onset cataract that is caused by foreign body well.
The ophthalmic dioptric lens that the present invention describes are in the common existence of people's natural crystal and are used for correcting refractive error.Concerning young patient, crystalline naturally adjusting focusing power still exists.It can not change because of implanting dioptric lens.This is because dioptric lens just are attached on the crystalline naturally front surface that is convex.
The ophthalmic dioptric lens that use the present invention to describe can make myopia (or hypermetropia) patient not need to wear glasses just can clearly see the world on every side.It is applicable to from low myopia (as 100 degree) to any myope between the myopia (as 3000 degree) highly, and simultaneously it is applicable to that also slight hypermetropia (as 100 degree) is to any farsighted person between the height hypermetropia (as 2000 degree).The ophthalmologist can report according to the patient's vision refractive error that optometrist provides, and selects corresponding ophthalmic dioptric lens exactly, implants in the patient's eye to make its vision correction for facing.
The method that the application of the invention is described can will be implanted ophthalmic by shrinking (folding, curling, stretching or compression etc.) method with it greater than the ophthalmic dioptric lens of operative incision.In general, skilled operative doctor only needs just can finish the operation of implanting the ophthalmic dioptric lens with ten minutes time.So, collapsible ophthalmic dioptric lens had both been corrected patient's refractive error, and the side effect that also makes operation bring simultaneously is reduced to a minimum.
The reversibility of the ophthalmic dioptric lens among the present invention is used extremely important.After myopia (or hypermetropia) patient accepted the operation of ophthalmic dioptric lens, owing to any reason, this patient was if wish to return to the ophthalmic dioptric lens state in the past of implanting, and the doctor just can take out the ophthalmic dioptric lens of having implanted by the pocket knife otch.Because people's vision changes in time, if some myopia patients have deepened or have reduced the near-sighted number of degrees after the several years, the doctor can be according to the test report of optometrist, select new ophthalmic dioptric lens, by the pocket knife otch, old ophthalmic dioptric lens are taken out, implant new ophthalmic dioptric lens.This reversibility of using the ophthalmic dioptric lens be use at present in the refractive surgery unique.By contrast, the laser refractive surgery is behind the cut-out cornea, and the doctor can't partly refill the cornea of removing at all.
Description of drawings
The invention will be further described below in conjunction with drawings and Examples.
Fig. 1 is the cutaway view of a kind of embodiment that is implanted in the ophthalmic dioptric lens of camera oculi posterior position.
Fig. 2 is the cutaway view of a kind of embodiment that is implanted in the ophthalmic dioptric lens of camera oculi anterior position.
Fig. 3 is the cutaway view of a kind of a kind of embodiment of the ophthalmic dioptric lens that are used for correction of myopia.
Fig. 4 is the vertical view of a kind of embodiment of ophthalmic dioptric lens among Fig. 3, and its supporter broadside is a curve.
Fig. 5 is the vertical view as a kind of embodiment of ophthalmic dioptric lens among Fig. 3, but the broadside of its supporter is a straight line.
Fig. 6 is a kind of cutaway view that is used to correct a kind of embodiment of presbyopic ophthalmic dioptric lens.
Fig. 7 is the vertical view of a kind of embodiment of ophthalmic dioptric lens among Fig. 6, and its supporter broadside is a curve.
Fig. 8 is the vertical view as a kind of embodiment of ophthalmic dioptric lens among Fig. 6, but the broadside of its supporter is a straight line.
Fig. 9 is the cutaway view of a kind of embodiment of the another kind ophthalmic dioptric lens that are used for correction of myopia.
Figure 10 is the vertical view of a kind of embodiment of ophthalmic dioptric lens among Fig. 9, and the broadside of its supporter is a curve.
Figure 11 is the vertical view as a kind of embodiment of ophthalmic dioptric lens among Fig. 9, but the broadside of its supporter is a straight line.
Figure 12 is the cutaway view that another kind is used to correct a kind of embodiment of presbyopic ophthalmic dioptric lens.
Figure 13 is the vertical view of a kind of embodiment of ophthalmic dioptric lens among Figure 12, and the broadside of its supporter is a curve.
Figure 14 is the vertical view as a kind of embodiment of ophthalmic dioptric lens among Figure 12, but the broadside of its supporter is a straight line.
Figure 15 is the vertical view as a kind of embodiment of ophthalmic dioptric lens among Fig. 5, Fig. 8, Figure 11, Figure 14, but respectively there is an aperture on the both sides of its supporter.
Figure 16 is the vertical view as a kind of embodiment of ophthalmic dioptric lens among Fig. 4, Fig. 7, Figure 10, Figure 13, but respectively there is an aperture on the both sides of its supporter.
Figure 17 is the vertical view as a kind of embodiment of ophthalmic dioptric lens among Fig. 3, Fig. 6, Fig. 9, Figure 12, but its supporter is oval-shaped, and respectively there is an aperture on both sides.
Figure 18 is the vertical view as a kind of embodiment of ophthalmic dioptric lens among Fig. 3, Fig. 6, Fig. 9, Figure 12, and its supporter has four outstanding fixing points.
Figure 19 is the vertical view of a kind of embodiment of the ophthalmic dioptric lens with two linear supporters of symmetry.
Figure 20 is the vertical view that another kind has the embodiment of two the linear supporter ophthalmic of symmetry dioptric lens.
Figure 21 is a kind of vertical view with embodiment of two asymmetric linear supporter ophthalmic dioptric lens.
Figure 22 is the vertical view of a kind of embodiment of the ophthalmic dioptric lens with three linear supporters.
The specific embodiment
As mentioned above, main purpose of the present invention provides a kind of ophthalmic dioptric lens, by simple, reversible operation these ophthalmic dioptric lens is implanted in camera oculi anterior or camera oculi posterior, to reach the effect of correcting defects of vision.Make myopia (or hypermetropia) patient not need the eyes fixing upward eyeball just can clearly see the world on every side.
One of the present invention is used for the specific embodiment 1 of ophthalmic dioptric lens of myopia correction shown in Fig. 1-5.
In Fig. 3, the ophthalmic dioptric lens are made up of optical bodies 30 institute that is connected with supporter 31, and optical bodies 30 is concave-concave curved surfaces, and the interlude radius of curvature of supporter 31 front surfaces is all the time greater than the radius of curvature of its rear surface.
The main design feature of present embodiment is an optical bodies 30 when being connected with supporter 31, and both rear surface curved surfaces are slick basically, its radius of curvature R
pBetween 9mm and 11mm, be preferably 10mm.So, the rear surface radius of curvature of optical bodies 30 is roughly the same with human natural crystal 12 front surface radius of curvature.Therefore, when ophthalmic dioptric lens 11 were implanted to camera oculi posterior, surface 101 was attached to nature crystal surface 102 before basically after its whole lens, has the very thin aqueous humour of one deck between the two.Relation and the relation between contact lens and the cornea between ophthalmic dioptric lens 11 and the natural crystal 12 are closely similar.On the one hand, contact lenses is attached to anterior corneal surface basically, on the other hand because anterior corneal surface always has tear lubricated, so, the very thin tear layer of one deck is always arranged between contact lens and anterior corneal surface.Similarly, no matter owing to be that anterior chamber 10 or back room all are full of aqueous humour in the eyeball, after ophthalmic dioptric lens 11 are implanted, its rear surface is the front surface that is attached to nature crystal 12 on the one hand basically, on the other hand, because the aqueous humour of ophthalmic is to flow to anterior chamber 10 from back room by pupil, this hydatoid flowing makes the thin water layer that is clipped between ophthalmic dioptric lens 11 and the natural crystal 12 obtain constantly replenishing and replacing upgrading, and this is the principal character reason place of the design of intraocular lens among the present invention.
Under normal conditions, the side effect of irrational ophthalmic dioptric lens design most probable generation is exactly because the ophthalmic dioptric lens directly touch the nature crystal to cause nature crystal generation mutation, it is muddy that consequently natural crystal gradually becomes, the cataract of promptly early turning white.This typical side effect of early onset cataract of being caused by foreign body has been avoided in the design of ophthalmic dioptric lens well among the present invention.
Other design features of ophthalmic dioptric lens are in the specific embodiment 1:
The scope of ophthalmic dioptric lens 11 total length L between the 13mm, is preferably 11mm at 10mm.
The scope of the width W of supporter 31 be 4.5mm between the 6.5mm, be preferably 6mm.
The thickness T of supporter 31
hScope be 0.15mm between the 0.3mm, be preferably 0.2mm.
The interlude radius of curvature R of supporter 31 front surfaces
hAlways greater than supporter rear surface radius of curvature R
p, R in the ordinary course of things
h=R
p+ T
h
One of the present invention is used for correcting the specific embodiment 2 of ophthalmic dioptric lens of hypermetropia shown in Fig. 6-8.
In Fig. 6, the ophthalmic dioptric lens by optical bodies 40 be connected with supporter 41 institute form.The optical bodies 40 of ophthalmic dioptric lens is concave curved surfaces behind the lordosis among the embodiment 2.
Dioptric lens length is lacked 0.5mm to 1.5mm than the corresponding lens that are used for myopia correction in the hypermetropia.
Other design features of specific embodiment 2 are identical with specific embodiment 1.
Ophthalmic dioptric lens among the present invention can be corrected any degree myopia or hypermetropia.Concerning near-sighted lens, the concave curved surface radius of optical bodies front surface is the refractive power of these lens of decision.In general, these lens can be corrected from 100 degree (1D) to 3000 degree (myopia 30D).Usually, the front surface concave curved surface radius of optical bodies can be according to the refractive index of material, and known facts such as diopter are calculated and got by the optical theory equation.In addition, the edge thickness T of concave surface optical bodies
eMust not preferably be not more than 0.7mm greater than 1mm generally speaking.In order to reach the ultimate value that is no more than this edge thickness, for the high myopia lens, just must reduce the diameter of optical bodies to bottom line 4.5mm.When making high dioptric lens, the optical bodies diameter sometimes even can reduce to 4mm.
Similarly, concerning distance-lens, usually its diopter can correct 100 degree (+1D) to 2000 degree (+20D) hypermetropiaes.In general, the optical bodies of distance-lens is the biconvex curved surface, and its center thickness is not more than 1mm.In order to be no more than this highest thickness limit value, when making extra-high-speed degree distance-lens, the diameter that can reduce optical bodies reaches this purpose.Same, the diameter of optical bodies at least will be at 4mm.
Based on common ultimate principle of the present invention, the present invention has exemplified shown in Fig. 9-11 another and has been used for the specific embodiment 3 of ophthalmic dioptric lens of myopia correction.
Similar to the design of specific embodiment 1,2, the optical bodies rear surface radius of curvature R of the ophthalmic dioptric lens of specific embodiment 3
pBetween 9mm and 11mm, preferred version is 10mm.Different with specific embodiment 1,2 is that the outside of the supporter of present embodiment also is connected with and first's supporter rear surface radius of curvature second portion supporter inequality.First's supporter 901 length greatly about 2mm between the 4mm, and the curvature of the curvature of its rear surface and optical bodies rear surface is basic identical.Therefore constitute smooth, a successive curved surface, can be attached to the crystalline front surface of nature.Outer end at first's supporter 901 also is connected with second portion supporter 902.The curvature of its curved surface is obviously different with first supporter 901.The length of second portion supporter 902 will be lacked than first's supporter 901, generally at 0.5mm between the 2mm.
When the ophthalmic dioptric lens of specific embodiment 3 were used for camera oculi posterior, the design of second portion supporter helped this part to be supported on above the ciliary zonule 15, thereby further reduced the ophthalmic dioptric lens to crystalline naturally pressure.On the other hand, when the lens of this design were used for camera oculi anterior, the length of first's supporter 901 will shorten 0mm to 2mm, and second portion supporter 902 will increase to 2mm to about the 4mm.So, just can avoid the optical bodies front surface of ophthalmic dioptric lens to run into the cornea interior surface layers.Will cause serious adverse because any foreign body brushes up against the endodermis cell of cornea interior surface layers, even cause cornea to become muddy and lose one's sight.In this design, second portion supporter 902 is to be used for fixing the support of optical body in pupil center location, brushes up against the endodermis cell of cornea to prevent optical bodies from leaning forward.For this reason, second portion supporter 902 length and width must suit, and are stretched over and are fixed on lightly anterior chamber's sunk area 16, to reach the purpose of fixing whole lens.An aperture can also be respectively established on the supporter both sides, its diameter d at 0.5mm between the 2.5mm, shown in Figure 15-17.During operation, the doctor can pierce into aperture to a branch of iris tissue with tweezers, and nail is the same to be fixed on whole lens in the anterior chamber space with regard to liking, and neither leans forward and runs into the cornea interior surface layers, and the nature crystal is run in not hypsokinesis again.Therefore the ophthalmic dioptric lens of this design also can be called the iris fixation lens.
Other design features are identical with specific embodiment 1 and 2 in the present embodiment.
Specific embodiment 4 is shown in Figure 12-14.Its design is similar to specific embodiment 3, and different is, and its optical bodies is a lordosis recurve curved-surface structure, is used to correct hypermetropia.
Basic principle and purpose according to the present invention, the supporter of the ophthalmic dioptric lens among the specific embodiment 1-4 all can adopt the contour structures shown in Figure 15-17.On the supporter aperture can be set.Aperture can be circular but be not limited to circle that its diameter range is that 0.5mm is to 2.5mm when being circle.When being used for the camera oculi posterior lens, the effect of this aperture is to be convenient to the doctor in when operation operation on the one hand, catch on aperture can mobile lens to correct position.On the other hand, aperture also can reduce lens and crystalline naturally contact surface and amasss.In addition, because the ophthalmic aqueous humour is constantly to flow to the anterior chamber by back room by pupil at any time, the existence of aperture also helps guaranteeing the unobstructed property of the preceding stream of aqueous humour.
Specific embodiment 5 as shown in figure 18.There are four fixing points 181,182,183,184 to be used for fixing whole lens on the supporter of these ophthalmic dioptric lens.But four fixing points must be slick and sly and not have the shape of very sharp an angle of 90 degrees, in order to avoid muscular tissue is on every side caused stimulation and brings side effect.Its optical bodies can be a bi-concave mirror body, also can be other shape mirror bodies such as lordosis recurve, its supporting body structure and length, width etc. the design can with specific embodiment 1-4 in any identical.
Specific embodiment 1-5 provided by the invention both had been applicable to the implantation camera oculi anterior, also was applicable to the implantation camera oculi posterior.For example Fig. 1 has described to be implanted in the cutaway view of the ophthalmic dioptric lens of iris back room position in the specific embodiment 1, and ophthalmic dioptric lens 11 are positioned at the back of iris 13, depend on the front surface of nature crystal 12.Fig. 2 has described to be implanted in the cutaway view of the ophthalmic dioptric lens of iris anterior chamber position, anterior chamber locus 10 places of ophthalmic dioptric lens 11 between iris 13 and cornea 14.
Specific embodiment 6-9 is shown in Figure 19-22.These ophthalmic dioptric lens mainly are applicable to the implantation camera oculi anterior.Be for simplicity equally, these embodiment only provide vertical view.In these embodiments, optical bodies 190,200,210,220 can be a biconcave mirror, also can be biconvex mirror or lordosis recurve combined lens, and its diameter D scope is that 4mm is to 6mm.Optical bodies is connected with two or more supporters.The material that is used to make supporter can be identical or different with the material of making optical bodies.The structure of supporter and shape are diversified.As the supporter among Figure 19 191 and 192 is symmetric.Supporter is inequality among Figure 20.Though and but two supporters among Figure 21 are identical asymmetric.Figure 22 then is the design example of plural supporter.In a word, although the structure of supporter and shape can be ever-changing, its purpose all be for the fixed optics body in anterior chamber's pupil center location, it is neither leaned forward runs into corneal endothelial layer, the nature crystal is run in not hypsokinesis again.The length L of supporter is defined as diagonal distance between the solstics, supporter two ends.Supporter length range among the specific embodiment of the invention 6-9 at 9mm between the 13mm.
Above-mentioned ophthalmic dioptric lens, its optical bodies can also can be made with whippy flexible material by rigid material such as polymethacrylates manufacturing, particularly utilizes the biocompatibility soft material to make the ophthalmic dioptric lens.Normally used biocompatibility soft material comprises (but being not restricted to) soft polypropylene esters of gallic acid, silicone rubber kinds, gel-like etc.This intraocular lens of being made by flexible material can reduce its sectional dimension by shrinking (folding, curl, stretching or compression etc.), so that can be by the pocket knife otch with its implantation camera oculi anterior or camera oculi posterior.Behind the folding implanted eyes of intraocular lens, because the elasticity of material and memory character, it can return to shape and the original diopter of estimating before folding.So, collapsible soft ophthalmic dioptric lens have not only been corrected patient's refractive error, and the side effect that also makes operation bring simultaneously is reduced to a minimum.
In addition, the above optical material can also contain and is used for absorbing ultraviolet chemical analysis.Can absorb ultraviolet material and contain benzotriazole class or Benzophenones chromophore usually, about the report of UV absorbent is seen United States Patent (USP) and pertinent literature (as US 4,985,559 and 5,194,544).
The present invention provides a kind of ophthalmic dioptric lens method for implantation with thorough solution refractive error (particularly high myopia, high hypermetropia) for the ophthalmologist very effectively.This method may further comprise the steps:
(1) on the eyes cornea or its edge slit one opening;
(2) dioptric lens of the present invention are shunk (folding, curl, stretching or compression etc.) and reduce its sectional dimension;
(3) dioptric lens after will shrinking are implanted ophthalmic by the pocket knife otch;
(4) dioptric lens that shrink are returned to the diopter of original shape and expectation.
Therefore, this use the ophthalmic dioptric lens method can with greater than the lens of operative incision by shrinking (folding, curl, stretching or compression etc.) with this ophthalmic dioptric lens implantation ophthalmic.In general, skilled operative doctor only needs just can finish the operation of implanting the ophthalmic dioptric lens with ten minutes time.
It should be noted that also it is reversible utilizing ophthalmic dioptric lens of the present invention to correct refractive error, this also is one of feature of ophthalmic dioptric lens using method provided by the invention.Present popular laser or other refractive surgery all belong to irreversible in general.After accepting the laser refractive surgery, if the patient is owing to any reason wishes to return to original state before the laser surgery, the doctor will feel simply helpless such as, the patient of myopia 500 degree.And concerning the operation of ophthalmic dioptric lens, the doctor just can take out the ophthalmic dioptric lens of having implanted by the pocket knife otch, and this patient just can return to the state of original near-sighted 500 degree.This reversible more significance is, myopia (or hypermetropia) patient particularly diopter of young patient is with advancing age and changing, the ophthalmologist can be according to the optometry report of optometrist, select new ophthalmic dioptric lens, by the pocket knife otch, old lens are taken out, implant new dioptric lens and make patient's vision correction for facing.It should be noted that equally: the ophthalmic dioptric lens can be corrected serious myopia or hypermetropia.For now, all popular refractive surgeries on market all can not be solved high myopia or high hypermetropia patient's refractive error.This also is unique another key characters of ophthalmic dioptric lens.
It should be noted that: ophthalmic dioptric lens of the present invention are in the common existence of people's natural crystal and are used for correcting refractive error.Concerning young patient, crystalline naturally adjusting focusing power still exists.It can not change because of implanting dioptric lens.This is because dioptric lens just are attached on the crystalline naturally front surface that is convex.
At last, it is also to be noted that what more than enumerate only is specific embodiments of the invention.Obviously, the invention is not restricted to above embodiment, many distortion can also be arranged.All distortion that those of ordinary skill in the art can directly derive or associate from content disclosed by the invention all should be thought protection scope of the present invention.
Claims (30)
1. ophthalmic dioptric lens, be connected with at least one supporter and form by being shaped as circular optical bodies, described optical bodies and supporter have front surface and rear surface, it is characterized in that, the rear surface of described dioptric lens is concave curved surface shape, and the optical bodies rear surface is identical with the smooth connection in supporter rear surface and both radius of curvature.
2. ophthalmic dioptric lens as claimed in claim 1 is characterized in that, the rear surface radius of curvature of described optical bodies and supporter is 9mm to 11mm.
3. ophthalmic dioptric lens as claimed in claim 1 is characterized in that, the rear surface radius of curvature of described optical bodies and supporter is 10mm.
4. ophthalmic dioptric lens as claimed in claim 1 is characterized in that, the interlude radius of curvature of described supporter front surface is all the time greater than the radius of curvature of its rear surface.
5. ophthalmic dioptric lens as claimed in claim 1 is characterized in that, described supporter outside also is connected with and this part supporter rear surface radius of curvature second portion supporter inequality.
6. ophthalmic dioptric lens as claimed in claim 5 is characterized in that, the length of described first supporter is 2mm to 4mm, and the length of described second portion supporter is 0.5mm to 2mm.
7. ophthalmic dioptric lens as claimed in claim 5 is characterized in that, the length of described first supporter is 0mm to 2mm, and the length of described second portion supporter is 2mm to 4mm.
8. as the described any ophthalmic dioptric lens of claim 1 to 7, it is characterized in that described dioptric lens total length is 10mm to 13mm.
9. as the described any ophthalmic dioptric lens of claim 1 to 7, it is characterized in that described dioptric lens total length is 11mm.
10. as the described any ophthalmic dioptric lens of claim 1 to 7, it is characterized in that the diameter of described optical bodies is 4mm to 6mm.
11., it is characterized in that the diameter of described optical bodies is 5mm as the described any ophthalmic dioptric lens of claim 1 to 7.
12., it is characterized in that the width of described supporter is 4.5mm to 6.5mm as the described any ophthalmic dioptric lens of claim 1 to 7.
13., it is characterized in that the width of described supporter is 6mm as the described any ophthalmic dioptric lens of claim 1 to 7.
14., it is characterized in that the thickness of described supporter is 0.15mm to 0.3mm as the described any ophthalmic dioptric lens of claim 1 to 7.
15., it is characterized in that the thickness of described supporter is 0.2mm as the described any ophthalmic dioptric lens of claim 1 to 7.
16., it is characterized in that when described optical bodies was the concave-concave toroidal lens, its center thickness was 0.01mm to 0.2mm as the described any ophthalmic dioptric lens of claim 1 to 7.
17., it is characterized in that when described optical bodies was the concave-concave toroidal lens, its center thickness was 0.1mm as the described any ophthalmic dioptric lens of claim 1 to 7.
18. as the described any ophthalmic dioptric lens of claim 1 to 7, it is characterized in that described supporter is shaped as rectangle, four summits are arc rather than rectangular-shaped.
19. ophthalmic dioptric lens as claimed in claim 18 is characterized in that the broadside of described supporter is arcual, its arc radius scope is 5mm to 7mm.
20., it is characterized in that described supporter is shaped as ellipse as the described any ophthalmic dioptric lens of claim 1 to 7.
21., it is characterized in that described supporter has four outstanding fixing points as the described any ophthalmic dioptric lens of claim 1 to 7.
22., it is characterized in that more than one aperture is arranged on the described supporter as the described any ophthalmic dioptric lens of claim 1 to 7.
23. ophthalmic dioptric lens as claimed in claim 22 is characterized in that, described aperture is circular, and its diameter range is 0.5mm to 2.5mm.
24. ophthalmic dioptric lens, form by a circular optical bodies and at least two linear supporters, it is characterized in that, described linear supporter directly is connected with optical bodies, so that optical bodies stably is fixed on eyes anterior chamber space pupil center location, avoid described optical bodies to contact with the cornea interior surface layers.
25. ophthalmic dioptric lens as claimed in claim 24 is characterized in that, the diameter range of described optical bodies is 4mm to 6mm.
26. ophthalmic dioptric lens as claimed in claim 24 is characterized in that, the total length scope of described lens is 9mm to 13mm.
27. the method for implantation such as the described any ophthalmic dioptric lens of claim 1 to 6 comprises the following steps:
On the eyes cornea or its edge slit one opening;
Described dioptric lens are shunk to reduce its sectional dimension;
Dioptric lens after shrinking are implanted the camera oculi posterior position of ophthalmic by the pocket knife otch;
The dioptric lens that shrink are returned to the diopter of original shape and expectation.
28. the method for the described any ophthalmic dioptric lens of implantation as claimed in claim 27 such as claim 1 to 6 is characterized in that, the mode that dioptric lens are shunk is folding, curling, stretching, compression.
29. the method for implantation such as claim 1,2,3,4,5,7 or 24 described any ophthalmic dioptric lens comprises the following steps:
On the eyes cornea or its edge slit one opening;
Described dioptric lens are shunk to reduce its sectional dimension;
Dioptric lens after shrinking are implanted the camera oculi anterior position of ophthalmic by the pocket knife otch;
The dioptric lens that shrink are returned to the diopter of original shape and expectation.
30. the method for implantation as claimed in claim 29 such as claim 1,2,3,4,5,7 or 24 described any ophthalmic dioptric lens is characterized in that, the mode that dioptric lens are shunk is folding, curling, stretching, compression.
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| CN 03115498 CN1248661C (en) | 2003-02-21 | 2003-02-21 | Intraocular phototropism lens and implantation method |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 03115498 CN1248661C (en) | 2003-02-21 | 2003-02-21 | Intraocular phototropism lens and implantation method |
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| CN1248661C CN1248661C (en) | 2006-04-05 |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103284831A (en) * | 2012-02-29 | 2013-09-11 | 北京大学第三医院 | Foldable glaucoma aqueous humor drainage device |
| US8778022B2 (en) | 2004-11-02 | 2014-07-15 | E-Vision Smart Optics Inc. | Electro-active intraocular lenses |
| WO2014108101A1 (en) * | 2013-01-14 | 2014-07-17 | Wang Qingyang | Intraocular lens |
| US9801709B2 (en) | 2004-11-02 | 2017-10-31 | E-Vision Smart Optics, Inc. | Electro-active intraocular lenses |
| CN107920920A (en) * | 2015-06-12 | 2018-04-17 | 综合医院公司 | Cornea filler for correction of refractive errors |
| CN108078652A (en) * | 2017-01-06 | 2018-05-29 | 爱博诺德（北京）医疗科技有限公司 | Posterior chamber type has crystal eye intraocular lens |
| CN109789241A (en) * | 2016-06-23 | 2019-05-21 | 麦迪凯姆研究所有限股份公司 | The hydrogel of tunable optical and biosimulation intraocular lens |
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2003
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US8778022B2 (en) | 2004-11-02 | 2014-07-15 | E-Vision Smart Optics Inc. | Electro-active intraocular lenses |
| US9801709B2 (en) | 2004-11-02 | 2017-10-31 | E-Vision Smart Optics, Inc. | Electro-active intraocular lenses |
| US10729539B2 (en) | 2004-11-02 | 2020-08-04 | E-Vision Smart Optics, Inc. | Electro-chromic ophthalmic devices |
| CN103284831A (en) * | 2012-02-29 | 2013-09-11 | 北京大学第三医院 | Foldable glaucoma aqueous humor drainage device |
| WO2014108101A1 (en) * | 2013-01-14 | 2014-07-17 | Wang Qingyang | Intraocular lens |
| CN107920920A (en) * | 2015-06-12 | 2018-04-17 | 综合医院公司 | Cornea filler for correction of refractive errors |
| CN107920920B (en) * | 2015-06-12 | 2021-05-25 | 综合医院公司 | Corneal filler for correcting ametropia |
| CN109789241A (en) * | 2016-06-23 | 2019-05-21 | 麦迪凯姆研究所有限股份公司 | The hydrogel of tunable optical and biosimulation intraocular lens |
| CN108078652A (en) * | 2017-01-06 | 2018-05-29 | 爱博诺德（北京）医疗科技有限公司 | Posterior chamber type has crystal eye intraocular lens |
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| CN1248661C (en) | 2006-04-05 |
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