CN108078570A - The Dynamic Blood Glucose Monitoring circuit and its control method of a kind of built-in acceleration sensor - Google Patents
The Dynamic Blood Glucose Monitoring circuit and its control method of a kind of built-in acceleration sensor Download PDFInfo
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
- A61B5/1477—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means non-invasive
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- A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
- A61B5/1116—Determining posture transitions
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- A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
- A61B5/1118—Determining activity level
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- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
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- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
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- A61B5/74—Details of notification to user or communication with user or patient ; user input means
- A61B5/746—Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms
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- A61B5/747—Arrangements for interactive communication between patient and care services, e.g. by using a telephone network in case of emergency, i.e. alerting emergency services
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Abstract
The Dynamic Blood Glucose Monitoring circuit and its control method of a kind of built-in acceleration sensor, are related to the wearable device and its control method for medical science, are connected and formed with emitter assemblies by the blood glucose sensor component of built-in blood glucose sensor；Emitter assemblies include sensor excitation module, sample conditioning module, ADC module, wireless SoC modules, flash memory module connects with emitter assemblies by the blood glucose sensor component of built-in blood glucose sensor and formed；Emitter assemblies include sensor excitation module, sample conditioning module, ADC module, wireless SoC modules and flash memory module, it can be while continuous acquisition and record blood sugar for human body, movement and the sleep info of wearer is obtained by 3-axis acceleration sensor, the identification for providing hypoglycemic coma is saved oneself with wake-up, glucose monitor data is sent to the intelligent handheld device of radio transmission-receiving function or other external reception terminals by wireless transmission mode, displays data analysis and remote-end alarm emergency service.
Description
Technical field
The present invention relates to the wearable device for medical science and its control methods more particularly to one kind to be used to move
State blood glucose measurement and the electronic circuit and its body-worn device of athletic posture detection.
Background technology
Blood sugar monitoring is the important component in diabetes management, and the result of blood sugar monitoring helps to assess patient of diabetes
The degree of person's carbohydrate metabolism disturbance specifies hypoglycemic scheme, while the effect for showing treatment and guides the adjustment to therapeutic scheme.Blood glucose
Concentration is related with several factors, such as moves, diet, medication etc..Traditional blood sugar monitoring methods are that acquisition refers to blood monitoring, but this
Method can not react patient's whole day blood glucose collection of illustrative plates, and there are monitoring blind areas.Therefore, developed recently goes out a kind of Dynamic Blood Glucose Monitoring production
Product can realize the blood sugar monitoring of whole day.For example, Chinese invention patent application " implanted low-consumption wireless blood sugar monitoring instrument "
(application for a patent for invention number：201410277574.3 publication number：CN104055525A a kind of implanted low-consumption wireless) is disclosed
Blood sugar monitoring instrument, including et al. Ke component and external component, the et al. Ke component includes implantable glucose sensor,
The implantable glucose sensor is connected with signal processing circuit, and the signal processing circuit is connected with microprocessor, described
Microprocessor is connected with the first wireless communication module, the implantable glucose sensor, and the signal processing circuit is described micro-
Processor and first wireless communication module are all connected with power supply module, the signal processing circuit, the microprocessor institute
It states wireless communication module and the power supply module all coats inside the shell；The external component include the second wireless communication module and
Host computer, second wireless communication module are connected with the host computer.A kind of Chinese utility model patent " wireless, real-time blood
Sugared recorder " (utility model patent number：ZL201520192338.1 Authorization Notice No.：CN204618248U a kind of nothing) is disclosed
Line, real time blood sugar recorder, are mainly made of monitoring side and APP terminals, and the monitoring side includes glucose inductive probe
And wireless data transmitter；The wireless data transmitter is connected with glucose inductive probe, and by glucose inductive probe
The blood glucose level data of offer reaches APP terminals；The APP terminals can analyze blood glucose level data and be shown on APP terminal screens
Blood sugar concentration.When glucose inductive probe detects electric current, electric signal numerical value is closely sent to APP by wireless data transmitter
Terminal, APP terminals can analyze blood glucose level data and blood sugar concentration, generation data and curves shown on APP terminal screens, are provided just
True insulin dosage.The technical solution can realize 24 it is small when monitor blood sugar concentration in real time；By wireless transmission, can effectively solve
Implantation subcutaneous position is too low to cause the problem of loosening of popping one's head in；Pass through APP terminal data processings, it is possibility to have effect solves equipment and carries
Inconvenient, flimsy problem.
Although above-mentioned prior art solves the continuous real-time test problems of blood glucose, realize blood sugar in diabetic patients
Horizontal dynamic monitoring.But such dynamic glucose product function is single, is only used for monitoring blood sugar for human body.And with blood glucose phase
The information such as the movement of pass, diet, medication can only be recorded manually.Chinese utility model patent " wireless blood glucose meter walks instrument "
(utility model patent number：ZL201220166396.3 Authorization Notice No.：CN202568265U) disclose a kind of with wireless biography
The blood-glucose meter step instrument of transmission function.It is to connect Keysheet module and display module, main control module respectively through main control module by power module
Blood glucose measurement module, note step module wireless transport module and memory module are connected respectively, and power module is above-mentioned module for power supply.Note
Step records simultaneously with glucose monitor data, and data are wirelessly transmitted to host computer according to one day or week age interval stores
With analysis.Blood glucose value and amount of exercise are monitored simultaneously, and with wireless transmission function, not only contribute to user to blood glucose value
Long term monitoring and tracking can also be diabetic and its people at highest risk by analyzing the relation between blood glucose and amount of exercise
Kinesiatrics is formulated, so as to delay or reduce the generation of diabetes and its complication.
Although above-mentioned prior art solves blood glucose value and some technical problems of amount of exercise monitoring respectively,
These prior arts perform blood sugar test using according to default time interval, and note step module therein is also only will
The function of pedometer is simply integrated into blood glucose meter, is used to implement the amount of exercise record of wearer, does not embody the two in function
On mutual support.
On the other hand, hypoglycemic coma is most common and most important complication in Course of Diabetes Treatment.Hypoglycemia
Stupor is that venous plasma concentration of glucose is less than patient's stupor caused during 2.8mmol/L (50mg/dl).With diabetes disease
The day for human beings becomes to increasing and aging of population old age hypoglycemic coma patient increases year by year, is counted according to certain emergency department of institute over 5 years, emergency treatment is just
The old stupor person examined accounts for 9%-12%, and which part patient obtains due to medical morning and treats in time, and another part patient is but because of hair
Now with medical delay treatment not in time, cause irreversible cerebral lesion even dead.Therefore, hypoglycemic coma must carry out promptly
A kind of wearable smart machine that disclosure satisfy that diabetic's nursing need is badly in need of in processing.
The content of the invention
The object of the present invention is to provide a kind of Dynamic Blood Glucose Monitoring circuits of built-in acceleration sensor, can continuously adopt
While collection and record blood sugar for human body, movement and the sleep info of wearer are obtained, the identification and wake-up of hypoglycemic coma are provided
Save oneself, and by way of wireless transmission by glucose monitor data be sent to intelligent handheld device with radio transmission-receiving function or
Other host computer terminals display data analysis and remote-end alarm emergency service.
Technical solution is used by the present invention solves above-mentioned technical problem：
A kind of Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor, by the blood glucose sensor group of built-in blood glucose sensor
Part connects composition with emitter assemblies；The emitter assemblies include sensor excitation module, sample conditioning module, ADC moulds
Block, wireless SoC modules and flash memory module, the sensor excitation module, which is connected to blood glucose sensor and provides voltage for it, to swash
It encourages, the sampled conditioning module of current signal of blood glucose sensor output is converted to voltage signal, and number is converted to by ADC module
Signal is transmitted to wireless SoC modules, and calculating blood glucose concentration value by computing is stored in flash memory module or by wirelessly connecting
Sending and receiving are sent to external reception terminal, it is characterised in that：
The emitter assemblies further include acceleration sensor module and motor wakes up alarm module；
The acceleration sensor module is connected to wireless SoC modules, and the wireless SoC modules are passed by acceleration
Sensor module gathers acceleration information, extracts the attitude measurement feature of wearer and movement statistics feature through data processing, obtains
The movement of human body and sleep info；
The motor wakes up alarm module and is connected to wireless SoC modules, and when finding wearer, there are hypoglycemic coma wind
When dangerous, the Dynamic Blood Glucose Monitoring circuit wakes up alarm module startup wake-up by motor and saves oneself, and passes through external reception terminal
Send low sugar stupor distress signal.
A kind of preferable technical solution of the Dynamic Blood Glucose Monitoring circuit of the built-in acceleration sensor of the present invention, feature
It is the blood glucose sensor component and emitter assemblies using separable structure, all circuits of the emitter assemblies
Component is packed using biocompatible materials, external contact V+, V-, S+, the S- for leaving connecting portion is packed, for even
Connect blood glucose sensor component；The blood glucose sensor component and emitter assemblies is connected and composed by connecting portion for dynamic blood
The Wearable blood glucose transmitter of glucose monitor.
A kind of superior technique scheme of the Dynamic Blood Glucose Monitoring circuit of the built-in acceleration sensor of the present invention, feature
It is that the emitter assemblies further include battery charging module, lithium battery and power management module；The blood glucose sensor
The contact V '+and V ' of component connecting portion-between be connected with switch element；When between emitter assemblies and blood glucose sensor component
When connecting portion disconnects, the contact V+ and V- of connecting portion form the charging input end of emitter assemblies, and accessible charging voltage passes through
Battery charging module charges to lithium battery；Terminate to remove charging voltage and not connected blood glucose sensing when emitter assemblies charge
During device assembly, the lithium battery of emitter assemblies is connected to power management module for electricity output with being disconnected inside power management module
Each circuit module at end is in power failure state；When needing to carry out blood sugar monitoring, built in the blood glucose sensor component
Blood glucose sensor is connected to emitter assemblies by the contact S+ and S- of connecting portion, and lithium battery passes through blood glucose sensor component internal
Switch element be connected to power management module, each circuit module of emitter assemblies powers on start-up operation.
A kind of improved technical solution of the Dynamic Blood Glucose Monitoring circuit of the built-in acceleration sensor of the present invention, feature
Be the switch element be connected to the contact V '+and V ' of the connecting portion-between PCB short-circuit lines.
A kind of further improved technical solution of the Dynamic Blood Glucose Monitoring circuit of the built-in acceleration sensor of the present invention,
It is characterized in that the switch element be connected to the contact V '+and V ' of the connecting portion-between touch switch, it is described to open
Pass element is negative logic pattern, and blood glucose transmitter works on power when switch element disconnects；Blood glucose is sent out when the switching element is closed
Emitter dead electricity is stopped, and transmitter remains powered off state；It by the closure of the switch element and backs off, realizes to nothing
The power on reset operation of line SoC modules.
It is a further object to provide a kind of Dynamic Blood Glucose Monitoring controls for above-mentioned Dynamic Blood Glucose Monitoring circuit
Method processed, used technical solution are：
A kind of Dynamic Blood Glucose Monitoring control method for above-mentioned Dynamic Blood Glucose Monitoring circuit, it is characterised in that including following
Step；
S100：The acquisition and pretreatment of dynamic glucose Concentration Testing data；
S200：The acquisition of human body attitude data and behavior act identification；
S300：The identification of hypoglycemic coma is saved oneself with wake-up and alert help；
S400：The wireless transmission of glucose monitor data.
A kind of preferable technical solution of the Dynamic Blood Glucose Monitoring control method of the present invention, it is characterised in that the step
S100 includes following action：
S110：Blood glucose transmitter power-up initializing；
S120：Bluetooth BLE modules built in blood glucose transmitter establish data by bluetooth BLE modes and mobile phone APP terminal
Communication connection；
S130：Start blood glucose sensor, current time, synchronous blood glucose sampling period are write to blood glucose transmitter；
S140：Blood glucose transmitter applies predetermined voltage drive to blood glucose sensor；
S150：Blood glucose sensor enters the polarization stand-by period；After the completion of polarization, mobile phone APP terminal writes reference blood glucose
Enter to blood glucose sensor；
S160：Blood glucose transmitter starts to gather the current signal in blood glucose sensor, after sampled conditioning module conditioning, leads to
It crosses ADC module sample conversion and is transmitted to wireless SoC modules into digital signal, calculate the blood glucose value for being converted to and representing blood sugar concentration；
S170：Blood glucose value is sent to mobile phone APP terminal by built-in bluetooth BLE modules by bluetooth approach.
A kind of superior technique scheme of the Dynamic Blood Glucose Monitoring control method of the present invention, it is characterised in that：
The step S200 includes following action：
S210：Blood glucose transmitter reads 3-axis acceleration by acceleration transducer and detects data；
S220：Data are detected according to 3-axis acceleration and carry out posture analysis and human action identification, by wearer's posture or
Operating state is sent to mobile phone APP terminal；
S230：If recognition result is walking or running state, gathers and send wearer's exercise data to cell phone application end
End, the exercise data include at least the step number of walking or running；
S240：If recognition result is wearer's tumble event, tumble alert help signal is sent by mobile phone APP terminal
To distal end APP terminals；
The step S300 includes following action：
S310：If recognition result is stupor or sleep state, S320 is gone to step；Otherwise return to step S210；
S320：If blood sugar monitoring result is hypoglycemia, judge that wearer there are hypoglycemic coma risk, goes to step
S330；Otherwise return to step S210；
S330：Alarm module is waken up by the motor built in blood glucose transmitter and starts the wake-up service of saving oneself；
S340：If wake-up is saved oneself effectively, return to step S210；Otherwise, low sugar stupor is sent by mobile phone APP terminal to ask
Signal is rescued to distal end APP terminals.
A kind of improved technical solution of the Dynamic Blood Glucose Monitoring control method of the present invention, it is characterised in that the step
S400 includes following action：
S410：Blood glucose transmitter judges connection status, if bluetooth connection is in connection status, goes to step S420 and otherwise returns
Blood glucose transmitter and mobile phone APP terminal is waited to re-establish connection；Since blood glucose signal can not be sent to cell phone application in real time at this time
Blood glucose value in acquisition is usually first stored temporarily in the flash memory module of SOC by terminal；
S420：Mobile phone APP terminal inquires about and reads historical data from flash memory module first；
S430：If historical data is all sent completely, into state is sent in real time, blood glucose transmitter will be most freshly harvested
Glucose monitor data is sent to mobile phone APP terminal.
The beneficial effects of the invention are as follows：
1st, the Dynamic Blood Glucose Monitoring circuit and its control method of built-in acceleration sensor of the invention, can continuously adopt
While collection and record blood sugar for human body, movement and the sleep info of wearer are obtained by 3-axis acceleration sensor, is provided low
The identification of blood glucose stupor is saved oneself with wake-up, and is sent to glucose monitor data by way of wireless transmission and is received with wireless
The intelligent handheld device or other external reception terminals of function are sent out, displays data analysis and remote-end alarm emergency service.
Motor is waken up and reported by the 2nd, the Dynamic Blood Glucose Monitoring circuit and its control method of built-in acceleration sensor of the invention
Alert module is placed in the emitter assemblies of blood glucose transmitter, is directly worn on human body；When detecting dangerous blood glucose signal, i.e.,
Make departing from wireless receiver, blood glucose transmitter still can directly send human body by motor wake-up alarm module and can perceive
Alarm, improve wake up self-rescue function reliability.
3rd, the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor of the invention, blood glucose sensor component and transmitter group
Part uses separable structure, and disposable blood glucose sensor component and the repeatable emitter assemblies utilized are separated, sent out
Emitter assemblies are reusable after charging, and can greatly save cost, by transmit wirelessly glucose monitor data transmitted it is in one's hands
Machine APP terminals pass through mobile phone APP terminal software and realize blood Sugar Monitoring and statistical analysis, it is convenient to omit special blood Sugar Monitoring is whole
The cost at end further mitigates patient medical burden.
Description of the drawings
Fig. 1 is the circuit block diagram of the Dynamic Blood Glucose Monitoring circuit of the built-in acceleration sensor of the present invention；
Fig. 2 is the structure diagram of the Dynamic Blood Glucose Monitoring instrument of the cell phone application direct monitoring of the present invention；
Fig. 3 is the cell phone application functional block diagram of the Dynamic Blood Glucose Monitoring instrument of cell phone application direct monitoring；
Fig. 4 is the control method flow chart of the Dynamic Blood Glucose Monitoring circuit of the built-in acceleration transducer for the present invention；
Fig. 5 is dynamic glucose Concentration Testing data acquisition process flow chart；
Fig. 6 is human body attitude detection and Activity recognition and the control flow chart for waking up relief；
Fig. 7 is the flow chart of glucose monitor data wireless transmission；
Fig. 8 is the battery charging module of the Dynamic Blood Glucose Monitoring circuit of the built-in acceleration sensor of the present invention；
Fig. 9 is the power management module of the Dynamic Blood Glucose Monitoring circuit of the built-in acceleration sensor of the present invention；
Figure 10 is the blood glucose Acquisition Circuit of the Dynamic Blood Glucose Monitoring circuit of the built-in acceleration sensor of the present invention；
Figure 11 is the ADC module of the Dynamic Blood Glucose Monitoring circuit of the built-in acceleration sensor of the present invention；
Figure 12 is the acceleration sensor module of the Dynamic Blood Glucose Monitoring circuit of the built-in acceleration sensor of the present invention；
Figure 13 is that the motor of the Dynamic Blood Glucose Monitoring circuit of the built-in acceleration sensor of the present invention wakes up alarm module；
Figure 14 is the wireless SoC modules of the Dynamic Blood Glucose Monitoring circuit of the built-in acceleration sensor of the present invention.
In figure, 100- blood glucose transmitters, 110- blood glucose sensor components, 120- emitter assemblies, 111- switch elements,
112- blood glucose sensors, 113- connecting portions, 121- sensor excitation modules, 122- sampling conditioning modules, 123- battery charging moulds
Block, 124- lithium batteries, 125- power management modules, 126- flash memory modules, 127- motors wake-up alarm module, 128-ADC modules,
SoC modules that 129- is wireless, 130- acceleration sensor modules, 200- mobile phone APP terminals, 210- user's registrations login module,
220- blood glucose level data monitoring modules, 230- event input modules, 240- data memory modules, 250- blood glucose level data sharing modules,
260- blood glucose level data statistical analysis modules, 270- nursing salvage service modules, the storage of 300- high in the clouds, 400- distal ends APP terminals.
Specific embodiment
For better understanding of the above-mentioned technical proposal of the present invention, carry out with reference to the accompanying drawings and examples further
It is described in detail.
One embodiment of the Dynamic Blood Glucose Monitoring circuit of the built-in acceleration sensor of the present invention is as shown in Figure 1, described
Dynamic Blood Glucose Monitoring circuit by built-in blood glucose sensor 112 120 connection group of blood glucose sensor component 110 and emitter assemblies
Into.The blood glucose sensor component 110 and emitter assemblies 130 use separable structure, the emitter assemblies 120
All circuit blocks are packed using biocompatible materials, pack the external contact V+, V-, S for leaving connecting portion 113
+, S-, for connecting blood glucose sensor component 110；The blood glucose sensor component 110 passes through 113 corresponding contact of connecting portion
V '+, V '-, S '+, S '-be connected to emitter assemblies 120, form the present invention cell phone application direct monitoring Dynamic Blood Glucose Monitoring
The Wearable blood glucose transmitter 100 of instrument.The present invention is by being used as the blood glucose sensor component 110 of disposable consumptive material with making
It is separated to be repeatable using the emitter assemblies 120 of component, client cost can be greatly saved.V+ in Fig. 1, V-, S+, S- are
The contact of the connecting portion 113 of 120 one side of emitter assemblies, V '+, V '-, S '+, S '-it is connecting portion 113 and blood glucose sensor component
110 electrical contacts being correspondingly connected with.
Embodiment according to figure 1, the emitter assemblies 120 include sensor excitation module 121, sampling conditioning
Module 122, ADC module 128, wireless SoC modules 129, flash memory module 126；The emitter assemblies 120 further include acceleration
Sensor assembly 130 and motor wake up alarm module 127.
The emitter assemblies 120 further include battery charging module 123, lithium battery 124 and power management module 125；
The connecting portion contact V '+and V ' of the blood glucose sensor component 110-between be connected with switch element 111；Work as emitter assemblies
When connecting portion 113 between 120 and blood glucose sensor component 110 disconnects, the electrical contact V+ and V- of connecting portion 113 are formed
The charging input end of emitter assemblies 120 can access 5V charging voltages, pass through the battery charging module 123 of emitter assemblies 120
It charges to lithium battery 124；
After 124 charging complete of lithium battery of emitter assemblies 120, remove 5V charging voltages, emitter assemblies 120 due to
It is not connected with blood glucose sensor component 110, lithium battery 124 and 125 inside of power management module disconnect, and are connected to power management
Each circuit module of the power supply output terminal of module 125 is in power failure state.This connection mode of emitter assemblies 120 can be real
Existing emitter assemblies 120 automatically power off, and so as to extend the stand-by time of emitter assemblies 120, extend 100 product of blood glucose transmitter
Stock's shelf cycle；
When needing to carry out blood sugar monitoring, the blood glucose sensor component 110 of blood glucose transmitter 100 is implanted into human body, blood glucose
Sensor module 110 is connected to by connecting portion 113 in emitter assemblies 120, and lithium battery 124 passes through blood glucose sensor component
Switch element 111 inside 110 is connected to power management module 125, and each circuit module of emitter assemblies 120 powers on beginning work
Make.
One embodiment of blood glucose sensor component 110 according to the present invention, the switch element 111 is is connected to
State the contact V '+and V ' of connecting portion 113-between PCB short-circuit lines.
Another embodiment of blood glucose sensor component 110 according to the present invention, the switch element 111 are to be connected to
The contact V '+and V ' of the connecting portion 113-between contact-making switch, the switch element 111 is operated in negative logic pattern：When
When switch element 111 disconnects, blood glucose transmitter 100 works on power；When the switching element is closed, blood glucose emits 100 dead electricity and stops
Work, emitter assemblies 110 remain powered off state；It by the closure of the switch element 111 and backs off, can realize pair
The power on reset operation of wireless SoC modules 129.In the present embodiment, the emitter assemblies 120 set short-circuit line equipped with interior
Contact protection lid, when the connecting portion 113 of the contact protection lid closing emitter assemblies 120, the short-circuit line will touch
Point V+ and V- short circuits, make emitter assemblies 120 remain powered off state, so as to extend the stand-by time of emitter assemblies 120, extend
Stock's shelf cycle of 100 product of blood glucose transmitter.
The wireless SoC modules 129 send instructions to sensor excitation module 121, it are made to apply sensor suitable
Voltage, the blood glucose sensor 112 in blood glucose sensor component 110 starts to work, and blood glucose sensor 112 generates faint electric current
Signal, this current signal reflect human body level.
The sampled conditioning module 122 of current signal that blood glucose sensor 112 generates is converted into voltage signal, filtered, send
To 128 circuit analog-to-digital conversion of ADC module, it is converted into digital signal and sends the wireless SoC modules 129 of governor circuit to, pass through fortune
Calculate and calculate human blood glucose concentration value, be stored in flash memory module 126 or cell phone application is sent to by wireless connection in real time
Terminal 200.
One embodiment of the battery charging module 123 is as shown in figure 8, be rechargeable lithium battery between wherein J1 and J2
124.U1 is charging management chip, preferably BQ24041, selects the resistance value setting battery charging rated current of resistance R18.Selection electricity
The resistance value setting battery charge cutoff electric current of R21 is hindered, selects R22 that the maximum current amplitude limit to charge is set.R23 pull down resistors, make
It can charging chip./ SHDN signals open shut-off for electric power management circuit, and specific logic is to work as V+, during V- short circuits ,/SHDN
Low level, turning off system power supply are pulled down to by R4 and D1；Charge power supply meets V+, during V- or hanging ,/SHDN outputs by R1 and
R4 is pulled to high voltage, and signal is sent to electric power management circuit, open system power supply.When in charging, CHG_PG output signals are
Height, CHG output signals are low.CHG exports high level when charging is complete；When CHG_PG is high, expression does not access charge power supply.
Pass through CHG_PG signals and CHG signal state, it can be determined that the working condition and charged state of transmitter, these states are sent to
SOC computings, it is then bright by the breath light progress connected on SOC, it goes out, flickers to indicate corresponding state.
One embodiment of the power management module 125 is as shown in Figure 9：The rated output voltage of lithium battery 124 is
3.7V or so, but the power supply of wireless SOC and the power supply of amplifier are 3V, and the reference voltage of transducer excitation voltage
For 1.25V.So the effect of power management module 125 is by power supply chip U2 (preferably UM1560DB) that 3.7V lithium batteries is defeated
Go out and be depressured to 3V, and accurately 1.25V reference voltages are given for utilization Precision reference power supply chip U3 (preferably REF3312) generations one
Sensor excitation circuit.Due to circuit, there are analog portions and numerical portion.In order to improve sampling precision and Immunity Performance, power supply
The PCB of management module 125 is using the measure of simulation ground/power supply and digitally/isolated from power, and using inductance L1, L2, L3 are isolation
Numerical portion and analog portion afterwards connects, and C2, C3, C4, C5 are power filtering capacitor.
According to embodiment shown in Fig. 10, the blood glucose of the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor of the invention
Acquisition Circuit includes sensor excitation module 121 and sampling conditioning module 122：Blood glucose sensor 112 is based on electrochemical principle
Work, it is necessary to apply the voltage drive of different stalls to sensor positive electrode S+ during normal work, wherein, Q2, R10, R12
Form voltage gear selection circuit.The gate pole V_SEL of Q2 is connected to the I/O pin of SoC chip, and voltage gear is selected by microcontroller.
When Q2 is turned on, R10 does not participate in operational amplifier circuit computing, generates voltage V1 to sensor anode S+.When Q2 is not turned on, R10 will be participated in
Operational amplifier circuit computing, S+ can generate voltage V2 to sensor anode S+.If also needing to the voltage of more grades, can be further added by
Voltage order one gear selection circuit.：The signal that blood glucose sensor 112 exports is current signal, it is necessary to sampled conditioning module 122
Processing, could generate the input voltage signal for being directly used in ADC module 128.Since the current level of blood glucose sensor 112 is very micro-
It is weak, it is nA ranks, therefore signal is nursed one's health using current/voltage operational amplifier circuit.R5 is feedback resistance in figure, and C7 is feedback
Capacitance, C7 are used to offset the influence of input capacitance, improve the response time, while regular hour constant is also provided together with R5.
U4 should select the accurate amplifier of Low-bias Current, the preferred 1M~2M Europe precision resistances of U4 preferred TSV712, wherein R5, it is contemplated that pass
Bandwidth is not high needed for sensor signal, the preferred 10nF~100nF of C7.The conditioned circuit conversion of current signal is defeated into after voltage signal
Go out ADC_GLU and be connected to adc circuit progress analog-to-digital conversion.According to the short principle of void of amplifier, the Pin5 of amplifier connects 1.25V voltages, phase
It is connected to when in sensor cathode S- on reference potential 1.25V.
One embodiment of the ADC module 128 is as shown in figure 11：In order to improve AD sampling precisions, the present embodiment uses
A piece of dedicated Differential Input high resolution A/D C conversion chips, preferably ADS1220, the output ADC_GLU of over-sampling modulate circuit and
The reference voltage 1.25V of sensor cathode S- can effectively reduce sampling noise as two Differential Inputs of ADC, this mode,
Improve the reliability of sampled result.The result of ADS1220 is output to SOC governor circuits by way of SPI and carries out computing.R14,
R16, C22, C27, C28 form signal filter circuit, can effectively filter out the common mode and differential mode noise of sampled signal.C20 and C21 are
Power filtering capacitor.According to another embodiment of the invention, the ADC module 128 is using built in wireless SoC modules 129
ADC function modules.
The acceleration sensor module 130 is connected to wireless SoC modules 129, and wireless SoC modules 129 pass through acceleration
It spends sensor assembly 130 and detects three-dimensional acceleration signal, the steric acceleration data of 100 wearer of acquisition blood glucose transmitter, warp
Attitude measurement feature and movement statistics feature are extracted in data processing, obtain movement and the sleep info of human body；By being based on posture
The tumble for measuring feature judges, before and after human body, it is lateral fall and stand rapidly after falling in the case of, can send and fall in time
The signal of falling alert help, and relevant information is recorded in flash memory module 126 or is sent to mobile phone APP terminal 200 in real time.
In view of influence of noise and fall detection algorithm to the high request of detection accuracy, can also be carried using Kalman filter algorithm
High algorithm accuracy.
One embodiment of acceleration sensor module 130 is as shown in figure 12：It is sensed in this example using 3-axis acceleration
Device U7 can be transported as acceleration test components, preferably model LSH3DH, 3-axis acceleration sensor not knowing object in advance
Under the occasion in dynamic direction, by detecting the steric acceleration of three-dimensional acceleration signal measurement object, so as to accurately reflect object comprehensively
The kinetic property of body, for example, extracting attitude measurement feature and movement system by the processing of the steric acceleration data to collecting
Feature is counted, including standard deviation, threshold value, the degree of bias, kurtosis etc., calculates standing, seat, prone position state and walking, race, the jump of identification wearer
Action obtains movement and the sleep info of human body.The data communication interface of acceleration transducer and wireless SOC circuits supports SPI
Or I2C interface, the present embodiment selection SPI interface, because the rate of SPI is far above I2C.C29 and C30 is power filter electricity
Hold.
The embodiment of the Dynamic Blood Glucose Monitoring circuit of the built-in acceleration sensor of the present invention according to figure 1, it is described
Emitter assemblies 120 further include motor and wake up alarm module 127；The motor wakes up alarm module 127 and is connected to wireless SoC
Module 129, when finding wearer there are during hypoglycemic coma risk, the Dynamic Blood Glucose Monitoring circuit is waken up by motor and reported
Alert module 127, which starts to wake up, saves oneself, and low sugar stupor distress signal is sent by external reception terminal.
One embodiment that the motor wakes up alarm module 127 is as shown in figure 13：The pull down resistor of metal-oxide-semiconductor input terminal
R26 is for ensureing restarting momentary motor remains stationary, because pin is high level to chip after the power is turned on, MOS is in the conduction state,
So that there are of short duration vibrations for motor.M+, M- connect eccentric vibrating motor.Pin Motor is connected to wireless SoC modules 129
Corresponding pin.D3 is fly-wheel diode when motor Q3 is disconnected.
It is extremely dangerous that at night hypoglycemia, which occurs, for diabetic.After especially patient sleep soundly, caused by hypoglycemia
Hypoglycemic coma cannot find that patient is powerless to save oneself or cry for help to others, and may be delayed rescue opportunity can even endanger in time
And life.Warning circuit is usually placed in wireless receiver by the existing blood glucose meter with warning function, but due to wirelessly connecing
The connection received between device and blood glucose transmitter may disconnect, even if blood glucose transmitter detects dangerous blood glucose signal at this time, the blood
Sugared data can be because connection, which disconnects, cannot be timely transmitted to wireless receiver；Wireless receiver not can know that patient is currently at
In dangerous blood sugar condition, thus alarm cannot be made.The Dynamic Blood Glucose Monitoring circuit of the built-in acceleration sensor of the present invention, will
Motor wakes up alarm module 127 and is placed in the emitter assemblies 120 of blood glucose transmitter 100, is directly worn on human body；Work as detection
During to dangerous blood glucose signal, even if departing from wireless receiver, blood glucose transmitter 100 still can wake up alarm mould by motor
Block 127 directly sends the appreciable alarm of human body.
Technical scheme takes gradual wake-up mode according to sleep state, can greatly improve user experience,
Patient is avoided because existing warning function often wakes up directly by it from sleep generates unhealthy emotion, and then it is low to close night
Blood glucose warning function and generate potential risk.
Embodiment according to Figure 14, the wireless SoC modules 129 are integrated with microprocessor cotex-M0 and bluetooth
Low energy consumption module (bluetooth BLE modules).Y2, C12, C14 composition low-frequency clock source, Y1, C10, C11 composition high frequency clocks source.
Pin19~Pin23 is the data communication interface of SOC and adc circuit, and Pin8~Pin11, Pin25, Pin26 is SOC and acceleration
The data communication interface of sensor assembly 130.Pin4 selects for the voltage gear of sensor excitation module 121.It is gone here and there on Pin5
R17 and D2 have been met, as the breath light of whole system, has realized the instruction of 100 simple state of blood glucose transmitter.Pin6, Pin7 are
The detection of battery status can detect that battery is in charging, charges and does not completely still access the states such as charge power supply.TP1~TP4
For program burn writing and emulation input port.L4, L5, L6, C17, C18, C19, C26 are balun circuit, while play antenna impedance
With effect.E1 is antenna.R13 and R15 is connected to the AD pin Pin48 of SOC by partial pressure, for the detection of battery capacity.
Although the wireless transmit/receive units in the present embodiment built in wireless SoC modules are preferably bluetooth BLE modules, in fact,
Wireless transmit/receive units can also be using zigbee, wifi or based on the ISM433/868/915Mhz frequency ranges for exempting to license
Communication；The near-field communication modes that NFC/RFID can also be used similar.
Technical scheme can also utilize acceleration sensor module 130 to provide step function and derivative energy
Function is consumed, and is applied it in glycemic control.For example, being counted for a period of time to certain, this section of time disease is counted
The step number and energy expenditure number of people excavates the step number of patient itself and the rule of change of blood sugar amount to the relation of change of blood sugar amount
Rule.If current blood glucose is higher, patient, which knows, needs how many step number that could blood glucose be dropped to safe range.
Fig. 2 is one embodiment of the Dynamic Blood Glucose Monitoring instrument of the cell phone application direct monitoring of the present invention, including a blood glucose
Transmitter 100, it is as at least one mobile phone APP terminal 200 of Dynamic Blood Glucose Monitoring exterior terminal and whole by cell phone application
The high in the clouds storage 300 of 200 connection of end；
The blood glucose transmitter 100 uses above-mentioned Dynamic Blood Glucose Monitoring circuit, including blood glucose sensor 112, sensor
Module 121 is encouraged, samples conditioning module 122, ADC module 128, wireless SoC modules 129 and acceleration sensor module 130
Alarm module 127 is waken up with motor；The sensor excitation module 121 applies driving voltage to blood glucose sensor 112；Institute
The sampling conditioning module 122 stated by the conditioning of the current signal of blood glucose sensor 112 into 128 matched voltage signal of ADC module；
Voltage signal after conditioning is converted into being sent to the master control core of the wireless SoC modules 129 of transmitter after digital signal by ADC module 128
Piece, main control chip calculate blood sugar concentration according to the digital signal of sample conversion, by being integrated in wireless SoC modules 129
Bluetooth BLE modules are sent to mobile phone APP terminal 200；The acceleration sensor module 130 is connected to wireless SoC modules
129, movement and the sleep info of human body are obtained, realizes that the identification of hypoglycemic coma and wake-up are saved oneself and alert help function；
The mobile phone APP terminal 200 is connected to blood glucose transmitter 100 by bluetooth mode, realizes the dynamic of blood sugar concentration
State monitors；The mobile phone APP terminal 200 is connected to high in the clouds storage 300 by mobile communication network；
Described high in the clouds storage 300 is used for storing the blood glucose level datas of blood glucose transmitter acquisition, and by authorized user
The network share of glucose monitor data is realized in push.
According to the embodiment of the Dynamic Blood Glucose Monitoring instrument of the cell phone application direct monitoring of the present invention shown in Fig. 2, work is further included
For at least one distal end APP terminals 400 of Dynamic Blood Glucose Monitoring exterior terminal；The distal end APP terminals 400 include at least blood
Sugared data monitoring module, blood glucose level data statistical analysis module and nursing relief alarm module；When mobile phone APP terminal 200 licenses to
After distal end APP terminals 400, distal end APP terminals 400 receive the number that blood glucose transmitter 100 is uploaded by mobile phone APP terminal 200
According to the strange land monitoring and statistical analysis of realization blood glucose transmitter；The nursing relief alarm module receives mobile phone APP terminal
The 200 nursing relief warning messages sent realize the distal end nursing relief alert service of hypoglycemic coma.The distal end APP
Terminal 400 includes the kinsfolk of wearer or mobile phone, tablet computer or the desktop computer of medical staff.
One implementation of the Dynamic Blood Glucose Monitoring instrument of cell phone application direct monitoring according to the present invention, as shown in figure 3, described
Mobile phone APP terminal 200 include following functions module：User's registration logins module 210, blood glucose level data monitoring module 220, event
Input module 230, data memory module 240, blood glucose level data sharing module 250, blood glucose level data statistical analysis module 260, nursing
Salvage service module 270；
The user's registration logins module 210 for the management of the system user account and user data authorized agreement；
The blood glucose level data monitoring module 220 is used to control the action of blood glucose transmitter 100, and receives blood glucose transmitter 100 and send out
The blood sugar concentration data sent, real-time display blood sugar concentration data；
The event input module 230 supports word input and speech recognition input, is capable of various dimensions record patient's
Life event provides medical information for diagnosis, and the life event includes motion exercise, medication, diet and daily life letter
Breath；
The data memory module 240 records blood sugar monitoring historical data and the life event, for understanding pair
The favourable habits and customs of blood glucose level；
The blood glucose level data sharing module 250 is by high in the clouds storage 300 by blood glucose level data real time propelling movement to kinsfolk
Or medical staff, realize the long-range monitoring to wearer's dynamic glucose；
The blood glucose level data statistical analysis module 260 is for counting blood sugar history data, during obtaining blood sugar monitoring
Change of blood sugar statistical law；
The nursing salvage service module 270 is used to receive the tumble alert help signal of the transmission of blood glucose transmitter 100
With low sugar stupor distress signal, nursing alert help information is sent to distal end APP terminals 400.
Fig. 4 is for the flow chart of the control method of the Dynamic Blood Glucose Monitoring circuit of above-mentioned built-in acceleration sensor, bag
Include following steps；
S100：The acquisition and pretreatment of dynamic glucose Concentration Testing data；
S200：The acquisition of human body attitude data and behavior act identification；
S300：The identification of hypoglycemic coma is saved oneself with wake-up and alert help；
S400：The wireless transmission of glucose monitor data.
Dynamic glucose Concentration Testing data acquisition process flow chart according to Fig. 5, the step S100 include with
Lower action：
S110：Blood glucose transmitter power-up initializing；
S120：Bluetooth BLE modules built in blood glucose transmitter establish data by bluetooth BLE modes and mobile phone APP terminal
Communication connection；
S130：Start blood glucose sensor, current time, synchronous blood glucose sampling period are write to blood glucose transmitter；
S140：Blood glucose transmitter applies predetermined voltage drive to blood glucose sensor；
S150：Blood glucose sensor enters the polarization stand-by period；After the completion of polarization, mobile phone APP terminal 200 is by reference blood glucose
It is written to blood glucose sensor；
S160：Blood glucose transmitter starts to gather the current signal in blood glucose sensor, after sampled conditioning module conditioning, leads to
It crosses ADC module sample conversion and is transmitted to wireless SoC modules into digital signal, calculate the blood glucose value for being converted to and representing blood sugar concentration；
S170：Blood glucose value is sent to mobile phone APP terminal by built-in bluetooth BLE modules by bluetooth approach.
The embodiment of the control method of Dynamic Blood Glucose Monitoring circuit according to Fig. 6, the step S200 include with
Lower action：
S210：Blood glucose transmitter reads 3-axis acceleration by acceleration transducer and detects data；
S220：Data are detected according to 3-axis acceleration and carry out posture analysis and human action identification, by wearer's posture or
Operating state is sent to mobile phone APP terminal；
S230：If recognition result is walking or running state, gathers and send wearer's exercise data to cell phone application end
End, the exercise data include at least the step number of walking or running；
S240：If recognition result is wearer's tumble event, tumble alert help signal is sent by mobile phone APP terminal
To distal end APP terminals；
The step S300 includes following action：
S310：If recognition result is stupor or sleep state, S320 is gone to step；Otherwise return to step S210；
S320：If blood sugar monitoring result is hypoglycemia, judge that wearer there are hypoglycemic coma risk, goes to step
S330；Otherwise return to step S210；
S330：Alarm module is waken up by the motor built in blood glucose transmitter and starts the wake-up service of saving oneself；
S340：If wake-up is saved oneself effectively, return to step S210；Otherwise, low sugar stupor is sent by mobile phone APP terminal to ask
Signal is rescued to distal end APP terminals.
According to embodiment shown in Fig. 7, the wireless transmission of glucose monitor data uses bluetooth mode.Since Bluetooth signal subtracts
The reason for weak loss or software requirement, in euglycemia gatherer process, the Bluetooth transmission module built in blood glucose transmitter 100
Connection status or off-state are likely to be at mobile phone APP terminal 200.Therefore, glucose monitor data is sent by two ways
To mobile phone APP terminal 200.The step S400 includes following action：
S410：Blood glucose transmitter judges connection status, if bluetooth connection is in connection status, goes to step S420 and otherwise returns
Blood glucose transmitter 100 and mobile phone APP terminal 200 is waited to re-establish connection；Since blood glucose signal can not be sent in real time at this time
Blood glucose value in acquisition is usually first stored temporarily in the flash memory module 126 of SOC by mobile phone APP terminal 200；
S420：Mobile phone APP terminal inquires about and reads historical data from flash memory module 126 first；
S430：If historical data is all sent completely, into state is sent in real time, blood glucose transmitter 100 is adopted newest
The glucose monitor data of collection is sent to mobile phone APP terminal.
After mobile phone APP terminal 200 receives the blood glucose concentration value of transmitter, real-time display is on mobile phone, while data are sent out
It is sent to high in the clouds storage 300.After blood glucose concentration value samples certain amount, APP user can select the side with precession diagram
Formula is shown so Historical Monitoring value.
When life event occurs for user, user can directly use word input or voice mode by the life thing
Part typing mobile phone APP terminal 200, the life event include diet, take exercise, the medication life thing related with blood glucose level
Part.Mobile phone APP terminal 200 can on the basis of the time point of event typing, before and after display event 3~5 it is small when blood glucose collection of illustrative plates,
For judging influence of the life event to blood sugar concentration.And each corresponding continuous blood sugar collection of illustrative plates of life event can be folded
Add, to compare observation.
After the completion of monitoring, mobile phone APP terminal 200 sends the order for terminating monitoring, blood glucose transmitter to blood glucose transmitter 100
100 are stopped, and blood glucose transmitter 100 from human body can be removed or disconnected emitter assemblies 120 and be passed with blood glucose by user
Connecting portion 113 between sensor component 110, emitter assemblies 120 are removed from human body, terminate entire blood sugar monitoring process.
Those of ordinary skill in the art it should be appreciated that more than embodiment be intended merely to illustrate the present invention's
Technical solution, and be not used as limitation of the invention, any connotation based on the present invention is to embodiment described above
Variation, the modification made will all fall in the scope of the claims of the present invention.
Claims (9)
1. a kind of Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor, by the blood glucose sensor component of built-in blood glucose sensor
Composition is connected with emitter assemblies；The emitter assemblies include sensor excitation module, sample conditioning module, ADC module,
Wireless SoC modules and flash memory module, the sensor excitation module are connected to blood glucose sensor and provide voltage drive, blood for it
The sampled conditioning module of current signal of sugared sensor output is converted to voltage signal, and digital signal is converted to by ADC module
Wireless SoC modules are transmitted to, calculating blood glucose concentration value by computing is stored in flash memory module or is sent out by wireless connection
It is sent to external reception terminal, it is characterised in that：
The emitter assemblies further include acceleration sensor module and motor wakes up alarm module；
The acceleration sensor module is connected to wireless SoC modules, and the wireless SoC modules pass through acceleration transducer
Module gathers acceleration information, extracts the attitude measurement feature of wearer and movement statistics feature through data processing, obtains human body
Movement and sleep info；
The motor wakes up alarm module and is connected to wireless SoC modules, when finding wearer there are during hypoglycemic coma risk,
The Dynamic Blood Glucose Monitoring circuit wakes up alarm module startup wake-up by motor and saves oneself, and is sent by external reception terminal low
Sugar stupor distress signal.
2. the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor according to claim 1, it is characterised in that described
Blood glucose sensor component and emitter assemblies are using separable structure, and all circuit blocks of the emitter assemblies are using life
Object compatibility material packs, and packs external contact V+, V-, S+, the S- for leaving connecting portion, for connecting blood glucose sensing
Device assembly；The blood glucose sensor component is connected with emitter assemblies by connecting portion, is formed for Dynamic Blood Glucose Monitoring
Wearable blood glucose transmitter.
3. the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor according to claim 2, it is characterised in that described
Emitter assemblies further include battery charging module, lithium battery and power management module；The blood glucose sensor component connecting portion
Contact V '+and V '-between be connected with switch element；When the connecting portion between emitter assemblies and blood glucose sensor component disconnects
When, the contact V+ and V- of connecting portion forms the charging input end of emitter assemblies, can access charging voltage and is charged mould by battery
Block charges to lithium battery；Terminate to remove charging voltage and during not connected blood glucose sensor component when emitter assemblies charge,
The lithium battery of emitter assemblies is connected to each circuit of power management module power supply output terminal with being disconnected inside power management module
Module is in power failure state；When needing to carry out blood sugar monitoring, the blood glucose sensor built in the blood glucose sensor component
Emitter assemblies, the switch element that lithium battery passes through blood glucose sensor component internal are connected to by the contact S+ and S- of connecting portion
Power management module is connected to, each circuit module of emitter assemblies powers on start-up operation.
4. the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor according to claim 3, it is characterised in that described
Switch element be connected to the contact V '+and V ' of the connecting portion-between PCB short-circuit lines.
5. the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor according to claim 3, it is characterised in that described
Switch element be connected to the contact V '+and V ' of the connecting portion-between contact-making switch, the switch element is operated in negative patrol
The pattern of collecting：When switch element disconnects, blood glucose transmitter works on power；When the switching element is closed, blood glucose transmitter dead electricity is stopped
It only works, transmitter remains powered off state；It by the closure of the switch element and backs off, realizes to wireless SoC modules
Power on reset operation.
6. a kind of Dynamic Blood Glucose Monitoring of the Dynamic Blood Glucose Monitoring circuit described in any claim for claim 1- to 5
Control method, it is characterised in that comprise the following steps：
S100：The acquisition and pretreatment of dynamic glucose Concentration Testing data；
S200：The acquisition of human body attitude data and behavior act identification；
S300：The identification of hypoglycemic coma is saved oneself with wake-up and alert help；
S400：The wireless transmission of glucose monitor data.
7. Dynamic Blood Glucose Monitoring control method according to claim 6, it is characterised in that the step S100 include with
Lower action：
S110：Blood glucose transmitter power-up initializing；
S120：Bluetooth BLE modules built in blood glucose transmitter establish data communication by bluetooth BLE modes and mobile phone APP terminal
Connection；
S130：Start blood glucose sensor, current time, synchronous blood glucose sampling period are write to blood glucose transmitter；
S140：Blood glucose transmitter applies predetermined voltage drive to blood glucose sensor；
S150：Blood glucose sensor enters the polarization stand-by period；After the completion of polarization, mobile phone APP terminal 200 writes reference blood glucose
To blood glucose sensor；
S160：Blood glucose transmitter starts to gather the current signal in blood glucose sensor, after sampled conditioning module conditioning, passes through
ADC module sample conversion is transmitted to wireless SoC modules into digital signal, calculates the blood glucose value for being converted to and representing blood sugar concentration；
S170：Blood glucose value is sent to mobile phone APP terminal by built-in bluetooth BLE modules by bluetooth approach.
8. Dynamic Blood Glucose Monitoring control method according to claim 6, it is characterised in that：
The step S200 includes following action：
S210：Blood glucose transmitter reads 3-axis acceleration by acceleration transducer and detects data；
S220：Data are detected according to 3-axis acceleration and carry out posture analysis and human action identification, by wearer's posture or action
State is sent to mobile phone APP terminal；
S230：If recognition result is walking or running state, gathers and send wearer's exercise data to mobile phone APP terminal,
The exercise data includes at least the step number of walking or running；
S240：If recognition result is wearer's tumble event, tumble alert help signal is sent to far by mobile phone APP terminal
Hold APP terminals；
The step S300 includes following action：
S310：If recognition result is stupor or sleep state, S320 is gone to step；Otherwise return to step S210；
S320：If blood sugar monitoring result is hypoglycemia, judge that wearer there are hypoglycemic coma risk, goes to step S330；
Otherwise return to step S210；
S330：Alarm module is waken up by the motor built in blood glucose transmitter and starts the wake-up service of saving oneself；
S340：If wake-up is saved oneself effectively, return to step S210；Otherwise, low sugar stupor emergency letter is sent by mobile phone APP terminal
Number to distal end APP terminals.
9. Dynamic Blood Glucose Monitoring control method according to claim 6, it is characterised in that the step S400 include with
Lower action：
S410：Blood glucose transmitter judges connection status, if bluetooth connection is in connection status, goes to step S420 and otherwise returns to waiting for
Blood glucose transmitter and mobile phone APP terminal re-establish connection；Since blood glucose signal can not be sent to cell phone application end in real time at this time
Blood glucose value in acquisition, is usually first stored temporarily in the flash memory module of SOC by end；
S420：Mobile phone APP terminal inquires about and reads historical data from flash memory module first；
S430：If historical data is all sent completely, into state is sent in real time, blood glucose transmitter will most freshly harvested blood glucose
Monitoring data are sent to mobile phone APP terminal.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111381540A (en) * | 2020-03-19 | 2020-07-07 | 乐普医学电子仪器股份有限公司 | Control device applied to continuous blood glucose monitoring sensor |
| WO2020221331A1 (en) * | 2019-04-30 | 2020-11-05 | 苏州百孝医疗科技有限公司 | Dynamic blood glucose monitoring transmitter and system with separate power supply, and signal sampling method |
| CN113274003A (en) * | 2019-08-19 | 2021-08-20 | 上海移宇科技股份有限公司 | Intelligent detection device |
| CN113892948A (en) * | 2021-09-30 | 2022-01-07 | 南京康博智慧健康研究院有限公司 | Intelligent blood sugar monitoring watch and working method |
| CN114748065A (en) * | 2022-04-28 | 2022-07-15 | 深圳可孚生物科技有限公司 | Self-powered implantable blood glucose monitoring device and method |
| WO2023103647A1 (en) * | 2021-12-07 | 2023-06-15 | 上海微创生命科技有限公司 | Blood glucose monitoring circuit and medical device |
Citations (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6175752B1 (en) * | 1998-04-30 | 2001-01-16 | Therasense, Inc. | Analyte monitoring device and methods of use |
| KR20050025882A (en) * | 2004-04-20 | 2005-03-14 | 주식회사 헬스피아 | Blood sugar management system |
| CN1960670A (en) * | 2004-04-01 | 2007-05-09 | 威廉·C·托奇 | Biosensors, communicators, and controllers for monitoring eye movement and methods for using them |
| CN2904945Y (en) * | 2006-04-14 | 2007-05-30 | 张金水 | Medical electronic thermometer and general purpose sensor thereof |
| US20070231846A1 (en) * | 2006-04-03 | 2007-10-04 | Cosentino Daniel L | Glucose meter communication method and system |
| CN101304697A (en) * | 2005-11-11 | 2008-11-12 | 爱森斯有限公司 | Method and apparatus for insertion of a sensor |
| KR20090103312A (en) * | 2008-03-28 | 2009-10-01 | 한국생명공학연구원 | Wireless Module Embedded Blood Glucose Test Meter |
| CN101600391A (en) * | 2007-02-01 | 2009-12-09 | Ric投资有限责任公司 | The metabolism measuring system that comprises function airway adapter |
| CN101627304A (en) * | 2007-03-14 | 2010-01-13 | 爱-森斯株式会社 | Electrochemical biosensor measuring system |
| US20100035334A1 (en) * | 2007-12-12 | 2010-02-11 | Eiji Okuda | Biological sample measurement apparatus |
| US7727147B1 (en) * | 2004-05-14 | 2010-06-01 | Flint Hills Scientific Llc | Method and system for implantable glucose monitoring and control of a glycemic state of a subject |
| US20110053121A1 (en) * | 2007-06-18 | 2011-03-03 | Roche Diagnostics International Ag | Method and glucose monitoring system for monitoring individual metabolic response and for generating nutritional feedback |
| WO2011075711A1 (en) * | 2009-12-17 | 2011-06-23 | Glumetrics, Inc. | System and method for maintaining glycemic control based on glucose activity measurements |
| US20130281796A1 (en) * | 2012-04-20 | 2013-10-24 | Broadmaster Biotech Corp. | Biosensor with exercise amount measuring function and remote medical system thereof |
| KR20140070486A (en) * | 2012-11-30 | 2014-06-10 | 에스디 바이오센서 주식회사 | Blood glucose measuring system using NFC and thereof method |
| CN104055525A (en) * | 2014-06-20 | 2014-09-24 | 中国科学院苏州生物医学工程技术研究所 | Implantable type low-consumption wireless blood glucose monitor |
| CN104323781A (en) * | 2014-11-10 | 2015-02-04 | 上海翰临电子科技有限公司 | Blood glucose analysis method and monitoring equipment |
| CN104732722A (en) * | 2015-04-19 | 2015-06-24 | 吴文灏 | Intelligent hypoglycemia monitoring alarm |
| CN204496656U (en) * | 2015-04-19 | 2015-07-22 | 吴文灏 | Hypoglycemia intelligent monitoring and alarming device |
| WO2016080911A1 (en) * | 2014-11-18 | 2016-05-26 | Nanyang Technological University | Server apparatus and wearable device for blood glucose monitoring and associated methods |
| US20160262707A1 (en) * | 2013-10-27 | 2016-09-15 | Blacktree Fitness Technologies Inc. | Portable devices and methods for measuring nutritional intake |
| KR20160109510A (en) * | 2015-03-11 | 2016-09-21 | 에스디 바이오센서 주식회사 | Device and method of blood glucose management for diabetic patients |
-
2016
- 2016-11-21 CN CN201611021436.4A patent/CN108078570B/en active Active
Patent Citations (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6175752B1 (en) * | 1998-04-30 | 2001-01-16 | Therasense, Inc. | Analyte monitoring device and methods of use |
| CN1960670A (en) * | 2004-04-01 | 2007-05-09 | 威廉·C·托奇 | Biosensors, communicators, and controllers for monitoring eye movement and methods for using them |
| KR20050025882A (en) * | 2004-04-20 | 2005-03-14 | 주식회사 헬스피아 | Blood sugar management system |
| US7727147B1 (en) * | 2004-05-14 | 2010-06-01 | Flint Hills Scientific Llc | Method and system for implantable glucose monitoring and control of a glycemic state of a subject |
| CN101304697A (en) * | 2005-11-11 | 2008-11-12 | 爱森斯有限公司 | Method and apparatus for insertion of a sensor |
| US20070231846A1 (en) * | 2006-04-03 | 2007-10-04 | Cosentino Daniel L | Glucose meter communication method and system |
| CN2904945Y (en) * | 2006-04-14 | 2007-05-30 | 张金水 | Medical electronic thermometer and general purpose sensor thereof |
| CN101600391A (en) * | 2007-02-01 | 2009-12-09 | Ric投资有限责任公司 | The metabolism measuring system that comprises function airway adapter |
| CN101627304A (en) * | 2007-03-14 | 2010-01-13 | 爱-森斯株式会社 | Electrochemical biosensor measuring system |
| US20110053121A1 (en) * | 2007-06-18 | 2011-03-03 | Roche Diagnostics International Ag | Method and glucose monitoring system for monitoring individual metabolic response and for generating nutritional feedback |
| US20100035334A1 (en) * | 2007-12-12 | 2010-02-11 | Eiji Okuda | Biological sample measurement apparatus |
| KR20090103312A (en) * | 2008-03-28 | 2009-10-01 | 한국생명공학연구원 | Wireless Module Embedded Blood Glucose Test Meter |
| WO2011075711A1 (en) * | 2009-12-17 | 2011-06-23 | Glumetrics, Inc. | System and method for maintaining glycemic control based on glucose activity measurements |
| US20130281796A1 (en) * | 2012-04-20 | 2013-10-24 | Broadmaster Biotech Corp. | Biosensor with exercise amount measuring function and remote medical system thereof |
| KR20140070486A (en) * | 2012-11-30 | 2014-06-10 | 에스디 바이오센서 주식회사 | Blood glucose measuring system using NFC and thereof method |
| US20160262707A1 (en) * | 2013-10-27 | 2016-09-15 | Blacktree Fitness Technologies Inc. | Portable devices and methods for measuring nutritional intake |
| CN104055525A (en) * | 2014-06-20 | 2014-09-24 | 中国科学院苏州生物医学工程技术研究所 | Implantable type low-consumption wireless blood glucose monitor |
| CN104323781A (en) * | 2014-11-10 | 2015-02-04 | 上海翰临电子科技有限公司 | Blood glucose analysis method and monitoring equipment |
| WO2016080911A1 (en) * | 2014-11-18 | 2016-05-26 | Nanyang Technological University | Server apparatus and wearable device for blood glucose monitoring and associated methods |
| KR20160109510A (en) * | 2015-03-11 | 2016-09-21 | 에스디 바이오센서 주식회사 | Device and method of blood glucose management for diabetic patients |
| CN104732722A (en) * | 2015-04-19 | 2015-06-24 | 吴文灏 | Intelligent hypoglycemia monitoring alarm |
| CN204496656U (en) * | 2015-04-19 | 2015-07-22 | 吴文灏 | Hypoglycemia intelligent monitoring and alarming device |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020221331A1 (en) * | 2019-04-30 | 2020-11-05 | 苏州百孝医疗科技有限公司 | Dynamic blood glucose monitoring transmitter and system with separate power supply, and signal sampling method |
| AT17919U1 (en) * | 2019-04-30 | 2023-07-15 | Suzhou Diascience Medical Co Ltd | Dynamic blood glucose measurement and transmission device with separate power supply and system |
| CN113274003A (en) * | 2019-08-19 | 2021-08-20 | 上海移宇科技股份有限公司 | Intelligent detection device |
| CN113274003B (en) * | 2019-08-19 | 2023-09-12 | 上海移宇科技股份有限公司 | Intelligent detection device |
| CN111381540A (en) * | 2020-03-19 | 2020-07-07 | 乐普医学电子仪器股份有限公司 | Control device applied to continuous blood glucose monitoring sensor |
| CN113892948A (en) * | 2021-09-30 | 2022-01-07 | 南京康博智慧健康研究院有限公司 | Intelligent blood sugar monitoring watch and working method |
| WO2023103647A1 (en) * | 2021-12-07 | 2023-06-15 | 上海微创生命科技有限公司 | Blood glucose monitoring circuit and medical device |
| CN114748065A (en) * | 2022-04-28 | 2022-07-15 | 深圳可孚生物科技有限公司 | Self-powered implantable blood glucose monitoring device and method |
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