CN206526052U - A kind of Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor - Google Patents

Abstract

A kind of Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor, is related to the wearable device for medical science, is made up of blood glucose sensor component and the emitter assemblies connection of built-in blood glucose sensor；Blood glucose sensor component and emitter assemblies use separable structure, and all circuit blocks of described emitter assemblies are packed using biocompatible materials, pack the outside contact V+ for leaving connecting portion, V, S+, S, for connecting blood glucose sensor component；Described blood glucose sensor component and emitter assemblies are connected by connecting portion, constitute the Wearable blood glucose transmitter for Dynamic Blood Glucose Monitoring.Motion and the sleep info of wearer is obtained by 3-axis acceleration sensor, the identification for providing hypoglycemic coma is saved oneself with wake-up, glucose monitor data is sent to the intelligent handheld device of radio transmission-receiving function or other external reception terminals by wireless transmission mode, DDA analysis and remote-end alarm emergency service is carried out.

Description

A kind of Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor

Technical field

The utility model is related to the wearable device for medical science, more particularly to a kind of dynamic glucose that is used for is surveyed Electronic circuit and its body-worn device that amount and athletic posture are detected.

Background technology

Blood sugar monitoring is the important component in diabetes management, and the result of blood sugar monitoring helps to assess patient of diabetes The degree of person's carbohydrate metabolism disturbance, specifies hypoglycemic scheme, while the effect for showing treatment and guides the adjustment to therapeutic scheme.Blood glucose Concentration is relevant with several factors, such as moves, diet, medication etc..Traditional blood sugar monitoring methods are that collection refers to blood monitoring, but this Method can not react patient's whole day blood glucose collection of illustrative plates, there is monitoring blind area.Therefore, developed recently goes out a kind of Dynamic Blood Glucose Monitoring production Product, can realize the blood sugar monitoring of whole day.For example, Chinese invention patent application " implanted low-consumption wireless blood sugar monitoring instrument " (application for a patent for invention number：201410277574.3, publication number：CN104055525A a kind of implanted low-consumption wireless) is disclosed Blood sugar monitoring instrument, including et al. Ke component and external component, the et al. Ke component include implantable glucose sensor, The implantable glucose sensor is connected with signal processing circuit, and the signal processing circuit is connected with microprocessor, described Microprocessor is connected with the first wireless communication module, the implantable glucose sensor, and the signal processing circuit is described micro- Processor and first wireless communication module are all connected with power supply module, the signal processing circuit, the microprocessor institute State wireless communication module and the power supply module is all coated in shell；The external component include the second wireless communication module and Host computer, the second wireless communication module and the host computer connection.A kind of Chinese utility model patent " wireless, real-time blood Sugared recorder " (utility model patent number：ZL201520192338.1 Authorization Notice No.：CN204618248U a kind of nothing) is disclosed Line, real time blood sugar recorder, it is mainly made up of monitoring side and APP terminals, and described monitoring side includes glucose inductive probe And wireless data transmitter；Described wireless data transmitter is connected with glucose inductive probe, and by glucose inductive probe The blood glucose level data of offer reaches APP terminals；Described APP terminals can analyze blood glucose level data and be shown on APP terminal screens Blood sugar concentration.When glucose inductive probe detects electric current, electric signal numerical value is closely sent to APP by wireless data transmitter Terminal, APP terminals can analyze blood glucose level data and blood sugar concentration, generation data and curves are shown on APP terminal screens, are provided just True insulin dosage.The technical scheme can realize 24 hours monitoring blood sugar concentrations in real time；By being wirelessly transferred, can effectively it solve Implantation subcutaneous position is too low to cause the problem of probe loosens；Pass through APP terminal data processings, it is possibility to have effect solves equipment and carried Inconvenient, flimsy problem.

Although above-mentioned prior art solves the continuous real-time test problems of blood glucose, realizes blood sugar in diabetic patients The dynamic monitoring of level.But, such dynamic glucose product function is single, is only used for monitoring blood sugar for human body.And with blood glucose phase The motion of pass, diet, the information such as medication can only be recorded manually.Chinese utility model patent " wireless blood glucose meter walks instrument " (utility model patent number：ZL201220166396.3 Authorization Notice No.：CN202568265U) disclose a kind of with wireless biography The blood-glucose meter step instrument of transmission function.It is through main control module to connect Keysheet module and display module, main control module respectively by power module Connection blood glucose measurement module, note walk module wireless transport module and memory module respectively, and power module is above-mentioned module for power supply.Note Step is recorded simultaneously with glucose monitor data, and data are wirelessly transmitted into host computer according to one day or week age interval is stored With analysis.Blood glucose value and amount of exercise are monitored simultaneously, and with wireless transmission function, not only contribute to user to blood glucose value Long term monitoring and tracking, can also be diabetic and its people at highest risk by analyzing the relation between blood glucose and amount of exercise Kinesiatrics is formulated, so as to delay or reduce diabetes and its generation of complication.

Although above-mentioned prior art solves some technical problems that blood glucose value is monitored with amount of exercise respectively, These prior arts perform blood sugar test using according to default time interval, and note step module therein is also only will The function of pedometer is simply integrated into blood glucose meter, for realizing that the amount of exercise of wearer is recorded, does not embody both in function On mutual support.

On the other hand, hypoglycemic coma be in Course of Diabetes Treatment it is most common, be also most important complication.Hypoglycemia Stupor is that venous plasma concentration of glucose is less than patient's stupor caused during 2.8mmol/L (50mg/dl).With diabetes disease People increases increasingly and the old hypoglycemic coma patient of aging population increases year by year, is counted according to certain emergency department of institute over 5 years, emergency treatment is just The old stupor person examined accounts for 9%-12%, and which part patient obtains and treated in time because medical early, and another part patient is but because of hair Now with medical delay treatment not in time, cause irreversible cerebral lesion even dead.Therefore, hypoglycemic coma must be carried out promptly Processing, is badly in need of a kind of wearable smart machine that disclosure satisfy that diabetic's nursing need.

Utility model content

The purpose of this utility model is to provide a kind of Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor, can be even While continuous collection and record blood sugar for human body, obtain wearer motion and sleep info there is provided the identification of hypoglycemic coma with Wake-up is saved oneself, and glucose monitor data is sent into the intelligent handhold with radio transmission-receiving function by way of wireless transmission set Standby or other host computer terminals, carry out DDA analysis and remote-end alarm emergency service.

The utility model solves the technical scheme that is used of above-mentioned technical problem：

A kind of Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor, by the blood glucose sensor group of built-in blood glucose sensor Part and emitter assemblies connection composition；It is characterized in that described blood glucose sensor component and emitter assemblies are using separable knot Structure, all circuit blocks of described emitter assemblies are packed using biocompatible materials, are packed outside and are left Contact V+, V-, S+, the S- of connecting portion, for connecting blood glucose sensor component；Described blood glucose sensor component and transmitter group Part is connected by connecting portion, constitutes the Wearable blood glucose transmitter for Dynamic Blood Glucose Monitoring.

A kind of preferably technical scheme of the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor of the present utility model, its It is characterised by that described emitter assemblies also include battery charging module, lithium battery and power management module；Described blood glucose is passed The contact V '+and V ' of sensor component connecting portion-between be connected with switch element；When emitter assemblies and blood glucose sensor component it Between connecting portion when disconnecting, the contact V+ and V- of connecting portion constitutes the charging input end of emitter assemblies, can access charging voltage Lithium battery is charged by battery charging module；When emitter assemblies charging end removes charging voltage and not connected blood glucose During sensor cluster, the lithium battery of emitter assemblies is connected to power management module and powered with being disconnected inside power management module Each circuit module of output end is in power failure state；When needing to carry out blood sugar monitoring, in described blood glucose sensor component The blood glucose sensor put is connected to emitter assemblies by the contact S+ and S- of connecting portion, and lithium battery passes through blood glucose sensor component Internal switch element is connected to electricity start-up operation on power management module, each circuit module of emitter assemblies.

A kind of superior technique scheme of the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor of the present utility model, its Be characterised by described switch element be connected to the contact V '+and V ' of the connecting portion-between PCB short-circuit lines.

A kind of improved technical scheme of the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor of the present utility model, its Be characterised by described switch element be connected to the contact V '+and V ' of the connecting portion-between touch switch, the switch Element is negative logic pattern, and when switch element disconnects, blood glucose transmitter works on power；Blood glucose is launched when the switching element is closed Device dead electricity is stopped, and transmitter remains powered off state；By the closure of the switch element and back off, realize to wireless The power on reset operation of SoC modules.

A kind of preferred technical scheme of the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor of the present utility model, its It is characterised by that described emitter assemblies also include acceleration sensor module and motor wakes up alarm module；Described acceleration Sensor assembly obtains motion and the sleep info of human body, realizes that the identification and wake-up of hypoglycemic coma are saved oneself and alert help work( Energy.

The beneficial effects of the utility model are：

1st, the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor of the present utility model, can be in continuous acquisition and record While blood sugar for human body, there is provided hypoglycemic coma for motion and sleep info by 3-axis acceleration sensor acquisition wearer Identification saved oneself with wake-up, and glucose monitor data is sent to radio transmission-receiving function by way of wireless transmission Intelligent handheld device or other external reception terminals, carry out DDA analysis and remote-end alarm emergency service.

2nd, the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor of the present utility model, motor wake-up alarm module is put In the emitter assemblies of blood glucose transmitter, directly it is worn on human body；When detecting dangerous blood glucose signal, even if departing from Wireless receiver, blood glucose transmitter still can wake up alarm module by motor and directly send the appreciable alarm of human body, Improve the reliability for waking up self-rescue function.

3rd, the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor of the present utility model, blood glucose sensor component and transmitting Device assembly uses separable structure, by disposable blood glucose sensor component and the repeatable emitter assemblies utilized point Open, it is reusable after emitter assemblies charging, cost can be greatlyd save, glucose monitor data is transmitted by transmitting wirelessly To mobile phone APP terminals, blood Sugar Monitoring and statistical analysis are realized by mobile phone A PP terminal softwares, it is convenient to omit special blood glucose prison The cost of control terminal, further mitigates patient medical burden.

Brief description of the drawings

Fig. 1 is the circuit block diagram of the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor of the present utility model；

Fig. 2 is the structural representation for the Dynamic Blood Glucose Monitoring instrument that mobile phone A PP of the present utility model is directly monitored；

Fig. 3 is the mobile phone A PP functional block diagrams for the Dynamic Blood Glucose Monitoring instrument that mobile phone A PP is directly monitored；

Fig. 4 is the control method flow of the Dynamic Blood Glucose Monitoring circuit of the built-in acceleration transducer for the utility model Figure；

Fig. 5 is dynamic glucose Concentration Testing data acquisition process flow chart；

Fig. 6 is human body attitude detection and Activity recognition and the control flow chart for waking up relief；

Fig. 7 is the flow chart of glucose monitor data wireless transmission；

Fig. 8 is the battery charging module of the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor of the present utility model；

Fig. 9 is the power management module of the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor of the present utility model；

Figure 10 is the blood glucose Acquisition Circuit of the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor of the present utility model；

Figure 11 is the ADC of the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor of the present utility model；

Figure 12 is the acceleration transducer mould of the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor of the present utility model Block；

Figure 13 is that the motor of the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor of the present utility model wakes up alarm mould Block；

Figure 14 is the wireless SoC modules of the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor of the present utility model.

In figure, 100- blood glucose transmitters, 110- blood glucose sensor components, 120- emitter assemblies, 111- switch elements, 112- blood glucose sensors, 113- connecting portions, 121- sensor excitation modules, 122- sampling conditioning modules, 123- batteries charging mould Block, 124- lithium batteries, 125- power management modules, 126- flash memory modules, 127- motors wake-up alarm module, 128-ADC modules, SoC modules that 129- is wireless, 130- acceleration sensor modules, 200- mobile phone A PP terminals, 210- user's registrations login module, 220- blood glucose level data monitoring modules, 230- event input modules, 240- data memory modules, 250- blood glucose level data sharing modules, 260- blood glucose level data statistical analysis modules, 270- nursing salvage service modules, the storage of 300- high in the clouds, 400- distal ends APP terminals.

Embodiment

For better understanding of above-mentioned technical proposal of the present utility model, traveling one is entered with reference to the accompanying drawings and examples It is described in detail on step ground.

One embodiment of the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor of the present utility model as shown in figure 1, Described Dynamic Blood Glucose Monitoring circuit is connected by the blood glucose sensor component 110 and emitter assemblies 120 of built-in blood glucose sensor 112 Connect composition.Described blood glucose sensor component 110 and emitter assemblies 130 uses separable structure, described emitter assemblies 120 all circuit blocks are packed using biocompatible materials, pack the outside contact V for leaving connecting portion 113 +, V-, S+, S-, for connecting blood glucose sensor component 110；Described blood glucose sensor component 110 passes through the correspondence of connecting portion 113 Contact V '+, V '-, S '+, S '-be connected to emitter assemblies 120, constitute that mobile phone A PP of the present utility model directly monitors is dynamic The Wearable blood glucose transmitter 100 of state blood sugar monitoring instrument.The utility model as the blood glucose of disposable consumptive material by passing Sensor component 110 is separated with as repeatable using the emitter assemblies 120 of component, can be greatly saved client cost.In Fig. 1 V+, V-, S+, S- for the side of emitter assemblies 120 connecting portion 113 contact, V '+, V '-, S '+, S '-be connecting portion 113 The electrical contact of connection corresponding with blood glucose sensor component 110.

Embodiment according to Fig. 1, described emitter assemblies 120 include sensor excitation module 121, sampling conditioning Module 122, ADC 128, wireless SoC modules 129, flash memory module 126；Described emitter assemblies 120 also include acceleration Sensor assembly 130 and motor wake up alarm module 127.

Described emitter assemblies 120 also include battery charging module 123, lithium battery 124 and power management module 125； The connecting portion contact V '+and V ' of described blood glucose sensor component 110-between be connected with switch element 111；Work as emitter assemblies When connecting portion 113 between 120 and blood glucose sensor component 110 is disconnected, the electrical contact V+ and V- of connecting portion 113 are constituted The charging input end of emitter assemblies 120, can access 5V charging voltages, passes through the battery charging module 123 of emitter assemblies 120 Lithium battery 124 is charged；

After 124 charging complete of lithium battery of emitter assemblies 120, remove 5V charging voltages, emitter assemblies 120 due to It is not connected with blood glucose sensor component 110, lithium battery 124 and the inside of power management module 125 disconnect, and are connected to power management Each circuit module of the power supply output end of module 125 is in power failure state.This connected mode of emitter assemblies 120 can be real Existing emitter assemblies 120 are automatically powered off, so that extend the stand-by time of emitter assemblies 120, the product of extension blood glucose transmitter 100 Stock's shelf cycle；

When needing to carry out blood sugar monitoring, the blood glucose sensor component 110 of blood glucose transmitter 100 is implanted into human body, blood glucose Sensor cluster 110 is connected in emitter assemblies 120 by connecting portion 113, and lithium battery 124 passes through blood glucose sensor component Switch element 111 inside 110 is connected on power management module 125, each circuit module of emitter assemblies 120 and establishes beginning work by cable Make.

According to one embodiment of blood glucose sensor component 110 of the present utility model, described switch element 111 is connection The connecting portion 113 contact V '+and V '-between PCB short-circuit lines.

According to another embodiment of blood glucose sensor component 110 of the present utility model, described switch element 111 is company Be connected on the contact V '+and V ' of the connecting portion 113-between contact-making switch, the switch element 111 is operated in negative logic mould Formula：When switch element 111 disconnects, blood glucose transmitter 100 works on power；When the switching element is closed, blood glucose launches 100 dead electricity It is stopped, emitter assemblies 110 remain powered off state；By the closure of the switch element 111 and back off, Neng Goushi Now to the power on reset operation of wireless SoC modules 129.In the present embodiment, described emitter assemblies 120 set short circuit equipped with interior The contact protection lid of line, when described contact protection lid closes the connecting portion 113 of emitter assemblies 120, described short-circuit line By contact V+ and V- short circuit, emitter assemblies 120 are made to remain powered off state, so that extend the stand-by time of emitter assemblies 120, Extend stock's shelf cycle of the product of blood glucose transmitter 100.

Described wireless SoC modules 129 send instructions to sensor excitation module 121, it is applied suitable to sensor Voltage, the blood glucose sensor 112 in blood glucose sensor component 110 starts working, and blood glucose sensor 112 produces faint electric current Signal, this current signal reflects human body level.

The sampled conditioning module 122 of current signal that blood glucose sensor 112 is produced is converted into voltage signal, filtered, send To the circuit analog-to-digital conversion of ADC 128, it is converted into data signal and sends the wireless SoC modules 129 of governor circuit to, passes through fortune Calculate and calculate human blood glucose concentration value, be stored in flash memory module 126, or be sent to by wireless connection mobile phone A PP in real time Terminal 200.

One embodiment of the battery charging module 123 is as shown in figure 8, be chargeable lithium cell between wherein J1 and J2 124.U1 is charging management chip, preferably BQ24041, selection resistance R18 resistance setting battery charging rated current.Selection electricity R21 resistance setting battery charge cutoff electric current is hindered, selection R22 sets the maximum current amplitude limit of charging.R23 pull down resistors, make Can charging chip./ SHDN signals open shut-off for electric power management circuit, and specific logic is to work as V+, during V- short circuits ,/SHDN Low level is pulled down to by R4 and D1, turning off system is powered；Charge power supply meets V+, during V- or hanging ,/SHDN outputs by R1 and R4 is pulled to high voltage, and signal delivers to electric power management circuit, and open system is powered.When in charging, CHG_PG output signals are Height, CHG output signals are low.CHG exports high level when charging is complete；When CHG_PG is high, expression does not access charge power supply. Pass through CHG_PG signals and CHG signal state, it can be determined that the working condition and charged state of transmitter, these states are sent to SOC computings, it is then bright by the breath light progress connected on SOC, go out, flash to indicate corresponding state.

One embodiment of the power management module 125 is as shown in Figure 9：The rated output voltage of lithium battery 124 is 3.7V or so, but wireless SOC power supply and the power supply of amplifier are 3V, and the reference voltage of transducer excitation voltage For 1.25V.So the effect of power management module 125 is by power supply chip U2 (preferably UM1560DB) that 3.7V lithium batteries is defeated Go out and be depressured to 3V, and accurately 1.25V reference voltages are given for utilization Precision reference power supply chip U3 (preferably REF3312) generations one Sensor excitation circuit.Because there is analog portion and numerical portion in circuit.In order to improve sampling precision and Immunity Performance, power supply The PCB of management module 125 is using the measure of simulation ground/power supply and digitally/isolated from power, and using inductance L1, L2, L3 is isolation Numerical portion and analog portion afterwards is connected, C2, C3, and C4, C5 is power filtering capacitor.

Embodiment according to Figure 10, the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor of the present utility model Blood glucose Acquisition Circuit includes sensor excitation module 121 and sampling conditioning module 122：Blood glucose sensor 112 is to be based on electrochemistry Principle work, it is necessary to apply the voltage drive of different gears to sensor positive electrode S+ during normal work, wherein, Q2, R10, R12 constitutes voltage gear selection circuit.Q2 gate pole V_SEL is connected to the I/O pin of SoC chip, and voltage gear is selected by single-chip microcomputer Position.When Q2 is turned on, R10 does not participate in discharge circuit computing, produces voltage V1 to sensor positive pole S+.When Q2 is not turned on, R10 will join With discharge circuit computing, S+ can produce voltage V2 to sensor positive pole S+.If also needing to the voltage of more grades, it can increase again Plus voltage order one gear selection circuit.：The signal that blood glucose sensor 112 is exported is current signal, it is necessary to sampled conditioning module 122 processing, could generate the input voltage signal for being directly used in ADC 128.Due to the current level of blood glucose sensor 112 It is very faint, it is nA ranks, therefore signal is nursed one's health using current/voltage discharge circuit.R5 is feedback resistance in figure, and C7 is Feedback capacity, C7 is used for the influence for offsetting input capacitance, the response time is improved, while it is normal that the regular hour is also provided together with R5 Number.U4 should select the accurate amplifier of Low-bias Current, the preferred 1M~2M Europe precision resistances of U4 preferred TSV712, wherein R5, it is considered to Bandwidth is not high needed for sensor signal, the preferred 10nF~100nF of C7.The conditioned circuit conversion of current signal is into voltage signal Afterwards, output ADC_GLU is connected to adc circuit and carries out analog-to-digital conversion.According to the empty short principle of amplifier, the Pin5 of amplifier connects 1.25V electricity Pressure, is connected on reference potential 1.25V equivalent to sensor negative pole S-.

One embodiment of the ADC 128 is as shown in figure 11：In order to improve AD sampling precisions, the present embodiment is used A piece of special Differential Input high resolution A/D C conversion chips, preferably ADS1220, the output ADC_GLU of over-sampling modulate circuit and Sensor negative pole S- reference voltage 1.25V can effectively reduce sampling noiset as two Differential Inputs of ADC, this mode, Improve the reliability of sampled result.ADS1220 result is output to SOC governor circuits by way of SPI and carries out computing.R14, R16, C22, C27, C28 constitute signal filter circuit, can effectively filter out the common mode and differential mode noise of sampled signal.C20 and C21 are Power filtering capacitor.According to another embodiment of the present utility model, described ADC 128 uses wireless SoC modules 129 Built-in ADC functional modules.

Described acceleration sensor module 130 is connected to wireless SoC modules 129, and wireless SoC modules 129 are by accelerating Spend the detection three-dimensional acceleration signal of sensor assembly 130, the steric acceleration data of the wearer of collection blood glucose transmitter 100, warp Attitude measurement feature and movement statistics feature are extracted in data processing, obtain motion and the sleep info of human body；By based on posture The tumble for measuring feature judges, before and after human body, it is lateral fall and fall after it is rapid stand in the case of, can in time send and fall The signal of falling alert help, and relevant information record is sent to mobile phone A PP terminals 200 in flash memory module 126, or in real time. In view of influence of noise and fall detection algorithm to the high request of detection accuracy, it can also be carried using Kalman filter algorithm High algorithm accuracy.

One embodiment of acceleration sensor module 130 is as shown in figure 12：Sensed in this example using 3-axis acceleration Device U7 can be transported as acceleration test components, preferably model LSH3DH, 3-axis acceleration sensor not knowing object in advance Under the occasion in dynamic direction, by detecting the steric acceleration of three-dimensional acceleration signal measurement object, so as to accurately reflect thing comprehensively The kinetic property of body, for example, extracting attitude measurement feature and motion system by the processing of the steric acceleration data to collecting Feature, including standard deviation, threshold value, the degree of bias, kurtosis etc. are counted, standing, seat, prone position state and walking, race, the jump of identification wearer is calculated Action, obtains motion and the sleep info of human body.The data communication interface of acceleration transducer and wireless SOC circuits supports SPI Or I2C interfaces, the present embodiment selection SPI interface, because SPI speed is far above I2C.C29 and C30 is power filter electricity Hold.

The embodiment of the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor of the present utility model according to Fig. 1, The emitter assemblies 120 also include motor and wake up alarm module 127；Described motor wakes up alarm module 127 and is connected to nothing Line SoC modules 129, when finding that wearer has hypoglycemic coma risk, described Dynamic Blood Glucose Monitoring circuit passes through motor Wake up the startup wake-up of alarm module 127 to save oneself, pass through external reception terminal and send low sugar stupor distress signal.

One embodiment that the motor wakes up alarm module 127 is as shown in figure 13：The pull down resistor of metal-oxide-semiconductor input R26 is used to ensure restarting momentary motor remains stationary, because pin is high level after electricity on chip, MOS is in the conduction state, So that there are of short duration vibrations in motor.M+, M- connect eccentric vibrating motor.Pin Motor is connected to wireless SoC modules 129 Corresponding pin.D3 is fly-wheel diode when motor Q3 disconnects.

It is extremely dangerous that at night hypoglycemia, which occurs, for diabetic.After especially patient sleep soundly, caused by hypoglycemia Hypoglycemic coma can not find that patient is powerless to save oneself or cried for help to others, may be delayed rescue opportunity or even can endanger in time And life.Warning circuit is generally placed in wireless receiver by the existing blood glucose meter with warning function, but is due to wirelessly to connect The connection received between device and blood glucose transmitter may disconnect, even if now blood glucose transmitter detects dangerous blood glucose signal, the blood Sugared data can be because connection disconnection can not be timely transmitted to wireless receiver；Wireless receiver not can know that patient is currently at In dangerous blood sugar condition, thus alarm can not be made.The Dynamic Blood Glucose Monitoring electricity of built-in acceleration sensor of the present utility model Road, motor wake-up alarm module 127 is placed in the emitter assemblies 120 of blood glucose transmitter 100, is directly worn on human body； When detecting dangerous blood glucose signal, even if departing from wireless receiver, blood glucose transmitter 100 still can be waken up by motor Alarm module 127 directly sends the appreciable alarm of human body.

The technical solution of the utility model takes gradual wake-up mode according to sleep state, can greatly improve user's body Test, it is to avoid patient is because existing warning function often wakes up generation unhealthy emotion directly by it from sleep, and then can close night Between hypoglycemia warning function and produce potential risk.

Embodiment according to Figure 14, described wireless SoC modules 129 are integrated with microprocessor cotex-M0 and bluetooth Low energy consumption module (bluetooth BLE modules).Y2, C12, C14 composition low-frequency clock source, Y1, C10, C11 composition high frequency clocks source. Pin19~Pin23 is the data communication interface of SOC and adc circuit, Pin8~Pin11, and Pin25, Pin26 is SOC and acceleration The data communication interface of sensor assembly 130.The voltage gear that Pin4 is used for sensor excitation module 121 is selected.Gone here and there on Pin5 R17 and D2 have been met, as the breath light of whole system, the instruction of the simple state of blood glucose transmitter 100 has been realized.Pin6, Pin7 are The detection of battery status, can detect that battery is in charging, and charging is full still not to access the states such as charge power supply.TP1~TP4 For program burn writing and emulation input port.L4, L5, L6, C17, C18, C19, C26 are balun circuit, while playing antenna impedance With effect.E1 is antenna.R13 and R15 is connected to SOC AD pin Pin48, the detection for battery electric quantity by partial pressure.

Although the wireless transmit/receive units in the present embodiment built in wireless SoC modules are preferably bluetooth BLE modules, in fact, Wireless transmit/receive units can also use zigbee, wifi, or based on the ISM433/868/915Mhz frequency ranges for exempting to license Communication；Can also be using near-field communication modes similar NFC/RFID.

The technical solution of the utility model can also provide step function and derivative using acceleration sensor module 130 Energy consumption function, and apply it in glycemic control.For example, being counted to certain a period of time, when counting this section Between patient step number and energy expenditure number to the relation of change of blood sugar amount, excavate the step number and change of blood sugar amount of patient itself Rule.If current blood glucose is higher, patient knows that blood glucose could be dropped to safe range by needs how many step number.

Fig. 2 is the one embodiment for the Dynamic Blood Glucose Monitoring instrument that mobile phone A PP of the present utility model is directly monitored, including one Blood glucose transmitter 100, as at least one mobile phone A PP terminals 200 of Dynamic Blood Glucose Monitoring exterior terminal, and passes through mobile phone The high in the clouds storage 300 that APP terminals 200 are connected；

Described blood glucose transmitter 100 uses above-mentioned Dynamic Blood Glucose Monitoring circuit, including blood glucose sensor 112, sensor Module 121 is encouraged, sample conditioning module 122, ADC 128, wireless SoC modules 129, and acceleration sensor module 130 Alarm module 127 is waken up with motor；Described sensor excitation module 121 applies driving voltage to blood glucose sensor 112；Institute The sampling conditioning module 122 stated nurses one's health into the current signal of blood glucose sensor 112 voltage signal matched with ADC 128； Voltage signal after conditioning is converted into being sent to the master control core of the wireless SoC modules 129 of transmitter after data signal by ADC 128 Piece, main control chip calculates blood sugar concentration according to the data signal of sample conversion, by being integrated in wireless SoC modules 129 Bluetooth BLE modules are sent to mobile phone A PP terminals 200；Described acceleration sensor module 130 is connected to wireless SoC modules 129, motion and the sleep info of human body are obtained, realizes that the identification and wake-up of hypoglycemic coma are saved oneself and alert help function；

Described mobile phone A PP terminals 200 are connected to blood glucose transmitter 100 by bluetooth mode, realize the dynamic of blood sugar concentration State is monitored；Described mobile phone A PP terminals 200 are connected to high in the clouds storage 300 by mobile communication network；

Described high in the clouds storage 300 is used for storing the blood glucose level datas of blood glucose transmitter collection, and by authorized user Push the network share for realizing glucose monitor data.

The embodiment for the Dynamic Blood Glucose Monitoring instrument that mobile phone A PP of the present utility model according to Fig. 2 is directly monitored, is also wrapped Include at least one distal end APP terminals 400 as Dynamic Blood Glucose Monitoring exterior terminal；Described distal end APP terminals 400 are at least wrapped Include blood glucose level data monitoring module, blood glucose level data statistical analysis module and nursing relief alarm module；When mobile phone A PP terminals 200 are awarded Weigh to after distal end APP terminals 400, distal end APP terminals 400 receive blood glucose transmitter 100 and uploaded by mobile phone A PP terminals 200 Data, realize blood glucose transmitter strange land monitoring and statistical analysis；It is whole that described nursing relief alarm module receives mobile phone A PP The nursing relief warning message that end 200 is sent, realizes the distal end nursing relief alert service of hypoglycemic coma.Described distal end APP terminals 400 include the kinsfolk of wearer or mobile phone, tablet personal computer or the desktop computer of medical personnel.

According to one of the mobile phone A PP of the present utility model Dynamic Blood Glucose Monitoring instrument directly monitored implementation, as shown in figure 3, Described mobile phone A PP terminals 200 include following functions module：User's registration logins module 210, blood glucose level data monitoring module 220, Event input module 230, data memory module 240, blood glucose level data sharing module 250, blood glucose level data statistical analysis module 260, Nurse salvage service module 270；

Described user's registration, which logins module 210, is used for management and the user data authorized agreement of the system user account； Described blood glucose level data monitoring module 220 is sent out for controlling the action of blood glucose transmitter 100, and receiving blood glucose transmitter 100 The blood sugar concentration data sent, show blood sugar concentration data in real time；

Described event input module 230 supports word input and speech recognition input, is capable of various dimensions record patient's Life event, medical information is provided for diagnosis, and described life event includes motion exercise, medication, diet and daily life letter Breath；

The described record blood sugar monitoring historical data of data memory module 240 and described life event, for understanding pair The favourable habits and customs of blood sugar level；

Described blood glucose level data sharing module 250 is by high in the clouds storage 300 by blood glucose level data real time propelling movement to kinsfolk Or medical personnel, realize the long-range monitoring to wearer's dynamic glucose；

Described blood glucose level data statistical analysis module 260 is used to count blood sugar history data, during obtaining blood sugar monitoring Change of blood sugar statistical law；

Described nursing salvage service module 270 is used for the tumble alert help signal for receiving the transmission of blood glucose transmitter 100 With low sugar stupor distress signal, nursing alert help information is sent to distal end APP terminals 400.

Fig. 4 is the flow chart of the control method of the Dynamic Blood Glucose Monitoring circuit for above-mentioned built-in acceleration sensor, bag Include following steps；

S100：The collection and pretreatment of dynamic glucose Concentration Testing data；

S200：The collection of human body attitude data and behavior act identification；

S300：The identification of hypoglycemic coma is saved oneself and alert help with wake-up；

S400：The wireless transmission of glucose monitor data.

Dynamic glucose Concentration Testing data acquisition process flow chart according to Fig. 5, described step S100 include with Lower action：

S110：Blood glucose transmitter power-up initializing；

S120：Bluetooth BLE modules built in blood glucose transmitter set up data by bluetooth BLE modes and mobile phone A PP terminals Communication connection；

S130：Start blood glucose sensor, current time, synchronous blood glucose sampling period are write to blood glucose transmitter；

S140：Blood glucose transmitter applies predetermined voltage drive to blood glucose sensor；

S150：Blood glucose sensor enters the polarization stand-by period；After the completion of polarization, mobile phone A PP terminals 200 are by reference blood glucose It is written to blood glucose sensor；

S160：Blood glucose transmitter starts to gather the current signal in blood glucose sensor, after sampled conditioning module conditioning, leads to Cross ADC sample conversion and be sent to wireless SoC modules into data signal, calculate the blood glucose value for being converted to and representing blood sugar concentration；

S170：Blood glucose value is sent to mobile phone A PP terminals by built-in bluetooth BLE modules by bluetooth approach.

The embodiment of the control method of Dynamic Blood Glucose Monitoring circuit according to Fig. 6, described step S200 include with Lower action：

S210：Blood glucose transmitter reads 3-axis acceleration by acceleration transducer and detects data；

S220：Detect that data carry out posture analysis and human action identification according to 3-axis acceleration, by wearer's posture or Operating state is sent to mobile phone A PP terminals；

S230：If recognition result is walking or running state, gathers and send wearer's exercise data to mobile phone APP ends End, described exercise data at least includes the step number of walking or running；

S240：If recognition result is wearer's tumble event, tumble alert help signal is sent by mobile phone A PP terminals To distal end APP terminals；

Described step S300 includes following action：

S310：If recognition result is stupor or sleep state, S320 is gone to step；Otherwise return to step S210；

S320：If blood sugar monitoring result is hypoglycemia, judges that wearer has hypoglycemic coma risk, go to step S330；Otherwise return to step S210；

S330：Alarm module is waken up by the motor built in blood glucose transmitter and starts the wake-up service of saving oneself；

S340：If wake-up is saved oneself effectively, return to step S210；Otherwise, low sugar stupor is sent by mobile phone A PP terminals to ask Signal is rescued to distal end APP terminals.

Embodiment according to Fig. 7, the wireless transmission of glucose monitor data uses bluetooth mode.Because Bluetooth signal subtracts The reason for weak loss or software requirement, in euglycemia gatherer process, the Bluetooth transmission module built in blood glucose transmitter 100 Connection status or off-state are likely to be at mobile phone A PP terminals 200.Therefore, glucose monitor data is sent by two ways To mobile phone A PP terminals 200.Described step S400 includes following action：

S410：Blood glucose transmitter judges connection status, if bluetooth connection is in connection status, goes to step S420 and otherwise returns Blood glucose transmitter 100 and mobile phone A PP terminals 200 is waited to re-establish connection；Because now blood glucose signal can not be sent in real time Blood glucose value in collection, is generally first stored temporarily in SOC flash memory module 126 by mobile phone A PP terminals 200；

S420：Mobile phone A PP terminals are inquired about and read historical data from flash memory module 126 first；

S430：If historical data is all sent completely, enters and send state in real time, blood glucose transmitter 100 is adopted newest The glucose monitor data of collection is sent to mobile phone A PP terminals.

Mobile phone A PP terminals 200 are received after the blood glucose concentration value of transmitter, are shown in real time on mobile phone, while data are sent out It is sent to high in the clouds storage 300.After blood glucose concentration value samples certain amount, APP user can select the side with precession diagram Formula is shown so Historical Monitoring value.

When life event occurs for user, user can directly use word input or voice mode by the life thing Part typing mobile phone A PP terminals 200, described life event includes diet, takes exercise, the medication life thing relevant with blood sugar level Part.Mobile phone A PP terminals 200 can be on the basis of the time point of event typing, the blood glucose collection of illustrative plates of 3~5 hours before and after display event, For judging influence of the life event to blood sugar concentration.And each corresponding continuous blood sugar collection of illustrative plates of life event can be folded Plus, to compare observation.

After the completion of monitoring, mobile phone A PP terminals 200 send the order for terminating monitoring, blood glucose transmitter to blood glucose transmitter 100 100 are stopped, and user can remove blood glucose transmitter 100 from human body, or disconnect emitter assemblies 120 and blood glucose biography Connecting portion 113 between sensor component 110, emitter assemblies 120 are removed from human body, terminate whole blood sugar monitoring process.

Those of ordinary skill in the art is it should be appreciated that the embodiment of the above is intended merely to illustrate that this practicality is new The technical scheme of type, and be not used as it is of the present utility model limit, it is any based on connotation of the present utility model to Change, modification that the upper embodiment is made, will all fall in scope of the claims of the present utility model.

Claims (5)

1. a kind of Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor, by the blood glucose sensor component of built-in blood glucose sensor Connect and constitute with emitter assemblies；It is characterized in that described blood glucose sensor component and emitter assemblies are using separable knot Structure, all circuit blocks of described emitter assemblies are packed using biocompatible materials, are packed outside and are left Contact V+, V-, S+, the S- of connecting portion, for connecting blood glucose sensor component；Described blood glucose sensor component and transmitter group Part is connected by connecting portion, constitutes the Wearable blood glucose transmitter for Dynamic Blood Glucose Monitoring.

2. the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor according to claim 1, it is characterised in that described Emitter assemblies also include battery charging module, lithium battery and power management module；Described blood glucose sensor component connecting portion Contact V '+and V '-between be connected with switch element；When the connecting portion between emitter assemblies and blood glucose sensor component disconnects When, the contact V+ and V- of connecting portion constitutes the charging input end of emitter assemblies, can access charging voltage and is charged mould by battery Block charges to lithium battery；When charging voltage and not connected blood glucose sensor component are removed in emitter assemblies charging end, The lithium batteries of emitter assemblies is connected to power management module and powered each circuit of output end with being disconnected inside power management module Module is in power failure state；When needing to carry out blood sugar monitoring, the blood glucose sensor built in described blood glucose sensor component Emitter assemblies, the switch element that lithium battery passes through blood glucose sensor component internal are connected to by the contact S+ and S- of connecting portion It is connected to electricity start-up operation on power management module, each circuit module of emitter assemblies.

3. the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor according to claim 2, it is characterised in that described Switch element be connected to the contact V '+and V ' of the connecting portion-between PCB short-circuit lines.

4. the Dynamic Blood Glucose Monitoring circuit of built-in acceleration sensor according to claim 2, it is characterised in that described Switch element be connected to the contact V '+and V ' of the connecting portion-between contact-making switch, the switch element is operated in negative patrol The pattern of collecting：When switch element disconnects, blood glucose transmitter works on power；When the switching element is closed, blood glucose transmitter dead electricity is stopped Only work, transmitter remains powered off state；By the closure of the switch element and back off, realize to wireless SoC modules Power on reset operation.

5. the Dynamic Blood Glucose Monitoring circuit of the built-in acceleration sensor according to any claim of Claims 1-4, It is characterized in that described emitter assemblies also include acceleration sensor module and motor wakes up alarm module；Described acceleration Motion and sleep info that sensor assembly obtains human body are spent, realizes that the identification and wake-up of hypoglycemic coma are saved oneself and alert help Function.